Browse by Current Cardiff authors

Almehdi, Ahmed M., Damiati, Samar, Shehadi, Ihsan A., El‐Sadek, Mohamed, Jones, Arwyn T. ORCID: https://orcid.org/0000-0003-2781-8905, El‐Kabalawy, Abdalla, Lashine, Yasmina, Nayak, Yogendra, Soliman, Sameh S. M., Westwell, Andrew D. ORCID: https://orcid.org/0000-0002-5166-9236 and Hamdy, Rania 2025. Next-generation Bcl-2 inhibitors: design and evaluation of indolyl-triazole derivatives with anticancer potential. ChemMedChem , e202500265. 10.1002/cmdc.202500265 Item availability restricted.

Alsulaimany, Marwa, Keniya, Mikhail V., Alanazi, Rehab S., Ruma, Yasmeen N., Hughes, Carwyn S., Jones, Arwyn T. ORCID: https://orcid.org/0000-0003-2781-8905, Tyndall, Joel D. A., Parker, Josie E., Monk, Brian C. and Simons, Claire ORCID: https://orcid.org/0000-0002-9487-1100 2025. Exploring long arm amide-linked side chains in the design of antifungal azole inhibitors of sterol 14α-demethylase (CYP51). Journal of Medicinal Chemistry 10.1021/acs.jmedchem.4c02922

Truyts, Alma, Du Preez, Ilse, Maesela, Eldas M., Scriba, Manfred R., Baillie, Les ORCID: https://orcid.org/0000-0002-8186-223X, Jones, Arwyn T. ORCID: https://orcid.org/0000-0003-2781-8905, Land, Kevin J., Verschoor, Jan A. and Lemmer, Yolandy 2024. Application of monoclonal anti-mycolate antibodies in serological diagnosis of tuberculosis. Tropical Medicine and Infectious Disease 9 (11) , p. 269. 10.3390/tropicalmed9110269

Rizzo, Siân, Varache, Mathieu ORCID: https://orcid.org/0000-0001-7166-2253, Sayers, Edward J. ORCID: https://orcid.org/0000-0002-2621-1119, Jones, Arwyn T. ORCID: https://orcid.org/0000-0003-2781-8905, Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976, Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 and Ferguson, Elaine L. ORCID: https://orcid.org/0000-0002-0125-0234 2024. Modification of the antibiotic, colistin, with dextrin causes enhanced cytotoxicity and triggers apoptosis in myeloid leukemia. International Journal of Nanomedicine 19 , pp. 5419-5437. 10.2147/IJN.S449185

Varache, Mathieu ORCID: https://orcid.org/0000-0001-7166-2253, Rizzo, Siân, Sayers, Edward J. ORCID: https://orcid.org/0000-0002-2621-1119, Newbury, Lucy, Mason, Anna, Liao, Chia-Te, Chiron, Emilie, Bourdiec, Nathan, Jones, Adam, Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342, Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421, Jones, Arwyn T. ORCID: https://orcid.org/0000-0003-2781-8905, Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 and Ferguson, Elaine L. ORCID: https://orcid.org/0000-0002-0125-0234 2024. Dextrin conjugation to colistin inhibits its toxicity, cellular uptake and acute kidney injury in vivo. RSC Pharmaceutics 1 , pp. 68-79. 10.1039/D3PM00014A

Hunter, Morag Rose, Cui, Lili, Porebski, Benjamin Thomas, Pereira, Sara, Sonzini, Silvia, Odunze, Uchechukwu, Iyer, Preeti, Engkvist, Ola, Lloyd, Rebecca Louise, Peel, Samantha, Sabirsh, Alan, Ross‐Thriepland, Douglas, Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 and Desai, Arpan Shailesh 2023. Understanding Intracellular Biology to Improve mRNA Delivery by Lipid Nanoparticles. small methods , 2201695. 10.1002/smtd.202201695

Lambourne, Olivia A., Bell, Shane, Wilhelm, Léa P., Yarbrough, Erika B., Holly, Gabriel G., Russell, Oliver M., Alghamdi, Arwa M., Fdel, Azeza M., Varricchio, Carmine ORCID: https://orcid.org/0000-0002-1673-4768, Lane, Emma L. ORCID: https://orcid.org/0000-0001-8800-3764, Ganley, Ian G., Jones, Arwyn T. ORCID: https://orcid.org/0000-0003-2781-8905, Goldberg, Matthew S. and Mehellou, Youcef ORCID: https://orcid.org/0000-0001-5720-8513 2023. PINK1-Dependent mitophagy inhibits elevated ubiquitin phosphorylation caused by mitochondrial damage. Journal of Medicinal Chemistry 66 (11) , pp. 7645-7656. 10.1021/acs.jmedchem.3c00555

Birch, Ditlev, Sayers, Edward J. ORCID: https://orcid.org/0000-0002-2621-1119, Christensen, Malene V., Jones, Arwyn T. ORCID: https://orcid.org/0000-0003-2781-8905, Franzyk, Henrik and Nielsen, Hanne M. 2023. Stereoisomer-dependent membrane association and capacity for insulin delivery facilitated by Penetratin. Pharmaceutics 15 (6) , 1672. 10.3390/pharmaceutics15061672

Daniele, Raffaella, Brazzale, Chiara, Arpac, Busra, Tognetti, Francesco, Pesce, Cristiano, Malfanti, Alessio, Sayers, Edward ORCID: https://orcid.org/0000-0002-2621-1119, Mastrotto, Francesca, Jones, Arwyn T. ORCID: https://orcid.org/0000-0003-2781-8905, Salmaso, Stefano and Caliceti, Paolo 2023. Influence of folate-targeted gold nanoparticles on subcellular localization and distribution into lysosomes. Pharmaceutics 15 (3) , 864. 10.3390/pharmaceutics15030864

Griffiths, Gareth, Gruenberg, Jean, Marsh, Mark, Wohlmann, Jens, Jones, Arwyn T. ORCID: https://orcid.org/0000-0003-2781-8905 and Parton, Robert G. 2022. Nanoparticle entry into cells; the cell biology weak link. Advanced Drug Delivery Reviews 188 , 114403. 10.1016/j.addr.2022.114403

Allemann, Rudolf K. ORCID: https://orcid.org/0000-0002-1323-8830, Samperio, Raquel, Mart, Robert ORCID: https://orcid.org/0000-0003-2196-5840, Luk, Louis ORCID: https://orcid.org/0000-0002-7864-6261, Tsai, Yu-Hsuan ORCID: https://orcid.org/0000-0003-0589-5088, Jones, Arwyn ORCID: https://orcid.org/0000-0003-2781-8905 and Cruz Samperio, Raquel 2022. Spatio-temporal control of cell death by selective delivery of photo-activatable proteins. ChemBioChem 23 (12) , e202200115. 10.1002/cbic.202200115

Aikman, Brech, Bonsignore, Riccardo, Woods, Ben, Doellerer, Daniel, Scotti, Riccardo, Schmidt, Claudia, Heidecker, Alexandra A., Pöthig, Alexander, Sayers, Edward J. ORCID: https://orcid.org/0000-0002-2621-1119, Jones, Arwyn T. ORCID: https://orcid.org/0000-0003-2781-8905 and Casini, Angela 2022. Highly-fluorescent BODIPY-functionalised metallacages as drug delivery systems: synthesis, characterisation and cellular accumulation studies. Dalton Transactions 51 (19) , pp. 7476-7490. 10.1039/D2DT00337F

Sayers, Edward John ORCID: https://orcid.org/0000-0002-2621-1119, Palmer, Iwan, Hope, Lucy, Hope, Paul, Watson, Peter ORCID: https://orcid.org/0000-0003-0250-7852 and Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2022. Fluid-phase endocytosis and lysosomal degradation of bovine lactoferrin in lung cells. Pharmaceutics 14 (4) , 855. 10.3390/pharmaceutics14040855

Sayers, Edward J. ORCID: https://orcid.org/0000-0002-2621-1119, Barlow, Victoria L., Tsai, Yu-Hsuan ORCID: https://orcid.org/0000-0003-0589-5088 and Jones, Arwyn T. ORCID: https://orcid.org/0000-0003-2781-8905 2022. Quantitative subcellular analysis of cyclic cell-penetrating peptide EJP18 in nonadherent cells. Cell Penetrating Peptides, Vol. 2383. Methods in Molecular Biology book series, Springer, pp. 211-228. (10.1007/978-1-0716-1752-6_14)

Gurney, Leo, Robson, Stephen C., Sweeney, Michèle, Jones, Arwyn T. ORCID: https://orcid.org/0000-0003-2781-8905 and Taggart, Michael J. 2022. Strategies for peptide-mediated cargo delivery to human smooth muscle cells. Langel, Ulo, ed. Cell Penetrating Peptides, Vol. 2383. Methods in Molecular Biology book series, Springer, pp. 459-471. (10.1007/978-1-0716-1752-6_29)

Padalino, Gilda, El-Sakkary, Nelly, Liu, Lawrence J., Liu, Chenxi, Harte, Danielle S.G., Barnes, Rachel E., Sayers, Edward ORCID: https://orcid.org/0000-0002-2621-1119, Forde-Thomas, Josephine, Whiteland, Helen, Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868, Ferla, Salvatore, Johnson, George, Jones, Arwyn T. ORCID: https://orcid.org/0000-0003-2781-8905, Caffrey, Conor R., Chalmers, Iain, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 and Hoffmann, Karl F. 2021. Anti-schistosomal activities of quinoxaline-containing compounds: From hit identification to lead optimisation. European Journal of Medicinal Chemistry 226 , 113823. 10.1016/j.ejmech.2021.113823

Hamdy, Rania, Jones, Arwyn T. ORCID: https://orcid.org/0000-0003-2781-8905, El-Sadek, Mohamed, Hamoda, Alshaimaa M., Shakartalla, Sarra B., AL Shareef, Zainab M., Soliman, Sameh S. M. and Westwell, Andrew D. ORCID: https://orcid.org/0000-0002-5166-9236 2021. New bioactive fused triazolothiadiazoles as Bcl-2-targeted anticancer agents. International Journal of Molecular Sciences 22 (22) , 12272. 10.3390/ijms222212272

Mills, Emily M., Barlow, Victoria L., Jones, Arwyn T. ORCID: https://orcid.org/0000-0003-2781-8905 and Tsai, Yu-Hsuan ORCID: https://orcid.org/0000-0003-0589-5088 2021. Development of mammalian cell logic gates controlled by unnatural amino acids. Cell Reports Methods 1 (6) , 100073. 10.1016/j.crmeth.2021.100073

Herkert, Ediz, Slesiona, Nicole, Recchia, Martina Elisena, Deckert, Thomas, Garcia-Parajo, Maria F., Fantuzzi, Eric Michele, Pruccoli, Andrea, Ragupathy, Imaiyan Chitra, Gudavičius, Dominykas, Rigneault, Hervé, Majer, Jan, Zumbusch, Andreas, Munger, Eleanor, Brasselet, Sophie, Jones, Arwyn T. ORCID: https://orcid.org/0000-0003-2781-8905, Watson, Peter ORCID: https://orcid.org/0000-0003-0250-7852, Boppart, Stephen A., Singh, Vikramdeep, Borkar, Saurabh, Quintela Rodriguez, Frank E., Langbein, Wolfgang, Petropoulos, Vasilis, van Hulst, Niek F., Maiuri, Margherita, Cerullo, Giulio, Brida, Daniele, Troiani, Filippo, Rozzi, Carlo Andrea, Molinari, Elisa, Vengris, Mikas and Borri, Paola ORCID: https://orcid.org/0000-0002-7873-3314 2021. Roadmap on bio-nano-photonics. Journal of Optics 23 (7) , 073001. 10.1088/2040-8986/abff94

Hamdy, Rania, Elseginy, Samia A., Ziedan, Noha I., El-Sadek, Mohamed, Lashin, Elsaid, Jones, Arwyn T. ORCID: https://orcid.org/0000-0003-2781-8905 and Westwell, Andrew D. ORCID: https://orcid.org/0000-0002-5166-9236 2020. Design, synthesis and evaluation of new bioactive oxadiazole derivatives as anticancer agents targeting Bcl-2. International Journal of Molecular Sciences 21 (23) , 8980. 10.3390/ijms21238980

Nödling, Alexander, Mills, Emily M., Li, Xuefei, Cardella, Davide, Sayers, Edward J. ORCID: https://orcid.org/0000-0002-2621-1119, Wu, Shih-Hsiung, Jones, Arwyn T. ORCID: https://orcid.org/0000-0003-2781-8905, Luk, Louis Y. P. ORCID: https://orcid.org/0000-0002-7864-6261 and Tsai, Yu-Hsuan ORCID: https://orcid.org/0000-0003-0589-5088 2020. Cyanine dye mediated mitochondrial targeting enhances the anti-cancer activity of small-molecule cargoes. Chemical Communications 56 (34) , pp. 4672-4675. 10.1039/C9CC07931A

Wymant, Jennifer Mary, Sayers, Edward John ORCID: https://orcid.org/0000-0002-2621-1119, Muir, Duncan and Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2020. Strategic trastuzumab mediated crosslinking driving concomitant HER2 and HER3 endocytosis and degradation in breast cancer. Journal of Cancer 11 (11) , pp. 3288-3302. 10.7150/jca.32470

Giannakopoulou, Naya, Williams, Joseph B., Moody, Paul R. ORCID: https://orcid.org/0000-0002-0191-2912, Sayers, Edward J. ORCID: https://orcid.org/0000-0002-2621-1119, Magnusson, Johannes P., Pope, Iestyn ORCID: https://orcid.org/0000-0002-4104-0389, Payne, Lukas, Alexander, Cameron, Jones, Arwyn T. ORCID: https://orcid.org/0000-0003-2781-8905, Langbein, Wolfgang ORCID: https://orcid.org/0000-0001-9786-1023, Watson, Peter ORCID: https://orcid.org/0000-0003-0250-7852 and Borri, Paola ORCID: https://orcid.org/0000-0002-7873-3314 2020. Four-wave-mixing microscopy reveals non-colocalisation between gold nanoparticles and fluorophore conjugates inside cells. Nanoscale 12 (7) , pp. 4622-4635. 10.1039/C9NR08512B

Eissa, N.G., Sayers, E.J. ORCID: https://orcid.org/0000-0002-2621-1119, Birch, D., Patel, S.G., Tsai, Y.-H. ORCID: https://orcid.org/0000-0003-0589-5088, Nielsen, H. Mørck and Jones, Arwyn ORCID: https://orcid.org/0000-0003-2781-8905 2020. EJP18 peptide derived from the juxtamembrane domain of epidermal growth factor receptor represents a novel membrane-active cell-penetrating peptide. Biochemical Journal 477 (1) , pp. 45-60. 10.1042/BCJ20190452

Sayers, Edward J. ORCID: https://orcid.org/0000-0002-2621-1119, Peel, Samantha E., Schantz, Anna, England, Richard M., Beano, Maya, Bates, Stephanie M., Desai, Arpan S., Puri, Sanyogitta, Ashford, Marianne B. and Jones, Arwyn T. ORCID: https://orcid.org/0000-0003-2781-8905 2019. Endocytic profiling of cancer cell models reveals critical factors influencing lipid nanoparticle mediated mRNA delivery and protein expression. Molecular Therapy 27 (11) , pp. 1950-1962. 10.1016/j.ymthe.2019.07.018

Woods, Ben, Dollerer, Daniel, Aikman, Brech, Wenzel, Margot ORCID: https://orcid.org/0000-0001-6411-1816, Sayers, Edward J. ORCID: https://orcid.org/0000-0002-2621-1119, Kühn, Fritz E., Jones, Arwyn T. ORCID: https://orcid.org/0000-0003-2781-8905 and Casini, Angela ORCID: https://orcid.org/0000-0003-1599-9542 2019. Highly luminescent metallacages featuring bispyridyl ligands functionalised with BODIPY for imaging in cancer cells. Journal of Inorganic Biochemistry 199 , 110781. 10.1016/j.jinorgbio.2019.110781

Lorenzer, Cornelia, Streußnig, Sonja, Tot, Emilia, Winkler, Anna-Maria, Merten, Hannes, Brandl, Fabian, Sayers, Edward J. ORCID: https://orcid.org/0000-0002-2621-1119, Watson, Peter ORCID: https://orcid.org/0000-0003-0250-7852, Jones, Arwyn T. ORCID: https://orcid.org/0000-0003-2781-8905, Zangemeister-Wittke, Uwe, Plückthun, Andreas and Winkler, Johannes 2019. Targeted delivery and endosomal cellular uptake of DARPin-siRNA bioconjugates: Influence of linker stability on gene silencing. European Journal of Pharmaceutics and Biopharmaceutics 141 , pp. 37-50. 10.1016/j.ejpb.2019.05.015

Wahlich, J., Desai, A., Greco, F., Hill, Kathryn, Jones, Arwyn T. ORCID: https://orcid.org/0000-0003-2781-8905, Mrsny, R., Pasut, G., Perrie, Y., Seib, F. P., Seymour, L. W. and Uchegbu, I. F. 2019. Nanomedicines for the delivery of biologics. Pharmaceutics 11 (5) , 210. 10.3390/pharmaceutics11050210

Patel, Sanjay G., Sayers, Edward J. ORCID: https://orcid.org/0000-0002-2621-1119, He, Lin, Narayan, Rohan, Williams, Thomas L., Mills, Emily M., Allemann, Rudolf K. ORCID: https://orcid.org/0000-0002-1323-8830, Luk, Louis Y. P. ORCID: https://orcid.org/0000-0002-7864-6261, Jones, Arwyn T. ORCID: https://orcid.org/0000-0003-2781-8905 and Tsai, Yu-Hsuan ORCID: https://orcid.org/0000-0003-0589-5088 2019. Cell-penetrating peptide sequence and modification dependent uptake and subcellular distribution of green florescent protein in different cell lines. Scientific Reports 9 (1) , -. 10.1038/s41598-019-42456-8

Hamdy, Rania, Elseginy, Samia, Ziedan, Noha, Jones, Arwyn ORCID: https://orcid.org/0000-0003-2781-8905 and Westwell, Andrew ORCID: https://orcid.org/0000-0002-5166-9236 2019. New quinoline-based heterocycles as anticancer agents targeting Bcl-2. Molecules 24 (7) , p. 1274. 10.3390/molecules24071274

Gurney, Leo R. I., Taggart, Julie, Tong, Wing-Chiu, Jones, Arwyn T. ORCID: https://orcid.org/0000-0003-2781-8905, Robson, Stephen C. and Taggart, Michael J. 2018. Inhibition of inflammatory changes in human myometrial cells by cell penetrating peptide and small molecule inhibitors of NFκB. Frontiers in Immunology 9 , 2966. 10.3389/fimmu.2018.02966

Sasso, Luana, Purdie, Laura, Grabowska, Anna, Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 and Alexander, Cameron 2018. Time and cell-dependent effects of endocytosis inhibitors on the internalization of biomolecule markers and nanomaterials. Journal of Interdisciplinary Nanomedicine 3 (2) , pp. 67-81. 10.1002/jin2.39

He, L., Sayers, E. J. ORCID: https://orcid.org/0000-0002-2621-1119, Watson, P. ORCID: https://orcid.org/0000-0003-0250-7852 and Jones, A. T. ORCID: https://orcid.org/0000-0003-2781-8905 2018. Contrasting roles for actin in the cellular uptake of cell penetrating peptide conjugates. Scientific Reports 8 (1) , 7318. 10.1038/s41598-018-25600-8

Sayers, Edward J. ORCID: https://orcid.org/0000-0002-2621-1119, Magnusson, Johannes P., Moody, Paul R. ORCID: https://orcid.org/0000-0002-0191-2912, Mastrotto, Francesca, Conte, Claudia, Brazzale, Chiara, Borri, Paola ORCID: https://orcid.org/0000-0002-7873-3314, Caliceti, Paolo, Watson, Peter ORCID: https://orcid.org/0000-0003-0250-7852, Mantovani, Giuseppe, Aylott, Jonathan, Salmaso, Stefano, Jones, Arwyn T ORCID: https://orcid.org/0000-0003-2781-8905 and Alexander, Cameron 2018. Switching of macromolecular ligand display by thermoresponsive polymers mediates endocytosis of multi-conjugate nanoparticles. Bioconjugate Chemistry 29 (4) , pp. 1030-1046. 10.1021/acs.bioconjchem.7b00704

Kjos, Ingrid, Borg Distefano, Marita, Sætre, Frank, Repnik, Urska, Holland, Petter, Jones, Arwyn T. ORCID: https://orcid.org/0000-0003-2781-8905, Engedal, Nikolai, Simonsen, Anne, Bakke, Oddmund and Progida, Cinzia 2017. Rab7b modulates autophagic flux by interacting with Atg4B. EMBO reports 18 (10) , pp. 1727-1739. 10.15252/embr.201744069

Roberts-Dalton, H. D. ORCID: https://orcid.org/0000-0003-4331-6067, Cocks, A., Falcon-Perez, J. M., Sayers, E. J. ORCID: https://orcid.org/0000-0002-2621-1119, Webber, J. P. ORCID: https://orcid.org/0000-0003-4772-3014, Watson, P. ORCID: https://orcid.org/0000-0003-0250-7852, Clayton, A. ORCID: https://orcid.org/0000-0002-3087-9226 and Jones, A. T. ORCID: https://orcid.org/0000-0003-2781-8905 2017. Fluorescence labelling of extracellular vesicles using a novel thiol-based strategy for quantitative analysis of cellular delivery and intracellular traffic. Nanoscale 9 (36) , pp. 13693-13706. 10.1039/C7NR04128D

Brazzale, C., Mastrotto, F., Moody, P., Watson, P. D. ORCID: https://orcid.org/0000-0003-0250-7852, Balasso, A., Malfanti, A., Mantovani, G., Caliceti, P., Alexander, C., Jones, A. T. ORCID: https://orcid.org/0000-0003-2781-8905 and Salmaso, S. 2017. Control of targeting ligand display by pH-responsive polymers on gold nanoparticles mediates selective entry into cancer cells. Nanoscale 9 (31) , pp. 11137-11147. 10.1039/C7NR02595E

Hamdy, Rania, Ziedan, Noha, Ali, Samina, Bordoni, Cinzia, El-Sadek, Mohamed, Lashin, Elsaid, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 and Westwell, Andrew D ORCID: https://orcid.org/0000-0002-5166-9236 2017. Synthesis and evaluation of 5-(1H-indol-3-yl)-N-aryl-1,3,4-oxadiazol-2-amines as Bcl-2 inhibitory anticancer agents. Bioorganic & Medicinal Chemistry Letters 27 (4) , pp. 1037-1040. 10.1016/j.bmcl.2016.12.061

Ziedan, Noha I, Hamdy, Rania, Cavaliere, Alessandra, Kourti, Malamati, Prencipe, Filippo, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Jones, Arwyn T ORCID: https://orcid.org/0000-0003-2781-8905 and Westwell, Andrew ORCID: https://orcid.org/0000-0002-5166-9236 2017. Virtual screening, SAR and discovery of 5-(indole-3-yl)-2-[(2-nitrophenyl)amino] [1,3,4]-oxadiazole as a novel Bcl-2 inhibitor. Chemical Biology and Drug Design 10.1111/cbdd.12936

Wymant, Jennifer, Moody, P., Sayers, Edward ORCID: https://orcid.org/0000-0002-2621-1119 and Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2017. Poster 433: Receptor-antibody clustering induced endocytosis of HER2 has therapeutic potential in breast cancer. Presented at: EACR-AACR-SIC Special Conference 2017: The Challenges of Optimising Immuno and Targeted Therapies From Cancer Biology to the Clinic, Florence, Italy, 24-27 June 2017.

Wymant, Jennifer, Hiscox, Stephen ORCID: https://orcid.org/0000-0003-0105-2702, Westwell, Andrew ORCID: https://orcid.org/0000-0002-5166-9236, Urbe, Sylvie, Clague, Michael and Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2016. The Role of BCA2 in the endocytic trafficking of EGFR and significance as a prognostic biomarker in cancer. Journal of Cancer 7 (15) , pp. 2388-2407. 10.7150/jca.15055

Kandil, Sahar ORCID: https://orcid.org/0000-0003-1806-9623, Wymant, Jennifer, Kariuki, Benson ORCID: https://orcid.org/0000-0002-8658-3897, Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905, McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X and Westwell, Andrew David ORCID: https://orcid.org/0000-0002-5166-9236 2016. Novel cis-selective and non-epimerisable C3 hydroxy azapodophyllotoxins targeting microtubules in cancer cells. European Journal of Medicinal Chemistry 110 , pp. 311-325. 10.1016/j.ejmech.2015.12.037

Gurney, Leo R. I., Robson, Stephen ORCID: https://orcid.org/0000-0003-3156-1487, Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 and Taggart, Michael 2016. Use of cell penetrating peptides to treat inflammatory responses in human uterine cells. Reproductive Sciences 23 , 292A-292A. 10.1177/1933719116641257

Moody, Paul R. ORCID: https://orcid.org/0000-0002-0191-2912, Sayers, Edward J. ORCID: https://orcid.org/0000-0002-2621-1119, Magnusson, Johannes P., Alexander, Cameron, Borri, Paola ORCID: https://orcid.org/0000-0002-7873-3314, Watson, Peter ORCID: https://orcid.org/0000-0003-0250-7852 and Jones, Arwyn T. ORCID: https://orcid.org/0000-0003-2781-8905 2015. Receptor crosslinking: a general method to trigger internalization and lysosomal targeting of therapeutic receptor: ligand complexes. Molecular Therapy 23 (12) , pp. 1888-1898. 10.1038/mt.2015.178

Lemmer, Yolandy, Kalombo, Lonji, Pietersen, Ray-Dean, Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905, Semete-Makokotlela, Boitumelo, Van Wyngaardt, Sandra, Ramalapa, Bathabile, Stoltz, Anton C., Baker, Bienyameen, Verschoor, Jan A., Swai, Hulda S. and de Chastellier, Chantal 2015. Mycolic acids, a promising mycobacterial ligand for targeting of nanoencapsulated drugs in tuberculosis. Journal of Controlled Release 211 , pp. 94-104. 10.1016/j.jconrel.2015.06.005

Cilibrasi, Vincenzo, Tsang, Kwok Ying Ingrid, Morelli, Matteo, Solfa, Francesca, Wiggins, Helen, Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 and Westwell, Andrew David ORCID: https://orcid.org/0000-0002-5166-9236 2015. Synthesis of substituted carbamo(dithioperoxo)thioates as potential BCA2-inhibitory anticancer agents. Tetrahedron Letters 56 (20) , pp. 2583-2585. 10.1016/j.tetlet.2015.03.132

Bahnsen, Jesper Soborg, Franzyk, Henrik, Sayers, Edward John ORCID: https://orcid.org/0000-0002-2621-1119 and Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2015. Cell-penetrating antimicrobial peptides - prospectives for targeting intracellular infections. Pharmaceutical Research 32 (5) , pp. 1546-1556. 10.1007/s11095-014-1550-9

Pereira, Paula, Pedrosa, Sílvia S., Wymant, Jennifer M., Sayers, Edward, Correia, Alexandra, Vilanova, Manuel, Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 and Gama, Francisco M. 2015. siRNA inhibition of endocytic pathways to characterize the cellular uptake mechanisms of folate functionalized glycol chitosan nanogels. Molecular Pharmaceutics 12 (6) , pp. 1970-1979. 10.1021/mp500785t

Wiggins, Helen L., Wymant, Jennifer M., Solfa, Francesca, Hiscox, Stephen E. ORCID: https://orcid.org/0000-0003-0105-2702, Taylor, Kathryn M. ORCID: https://orcid.org/0000-0002-9576-9490, Westwell, Andrew D. ORCID: https://orcid.org/0000-0002-5166-9236 and Jones, Arwyn T. ORCID: https://orcid.org/0000-0003-2781-8905 2015. Disulfiram-induced cytotoxicity and endo-lysosomal sequestration of zinc in breast cancer cells. Biochemical Pharmacology 93 (3) , pp. 332-342. 10.1016/j.bcp.2014.12.014

Webber, J. P. ORCID: https://orcid.org/0000-0003-4772-3014, Spary, L. K., Sanders, A. J. ORCID: https://orcid.org/0000-0002-7997-5286, Chowdhury, R., Jiang, W. G. ORCID: https://orcid.org/0000-0002-3283-1111, Steadman, R. ORCID: https://orcid.org/0000-0002-1303-2496, Wymant, J., Jones, A. T. ORCID: https://orcid.org/0000-0003-2781-8905, Kynaston, H. ORCID: https://orcid.org/0000-0003-1902-9930, Mason, M. D. ORCID: https://orcid.org/0000-0003-1505-2869, Tabi, Z. and Clayton, A. ORCID: https://orcid.org/0000-0002-3087-9226 2015. Differentiation of tumour-promoting stromal myofibroblasts by cancer exosomes. Oncogene 34 (3) , pp. 290-302. 10.1038/onc.2013.560

He, Lin, Watson, Peter Duncan ORCID: https://orcid.org/0000-0003-0250-7852 and Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2015. Visualizing actin architectures in cells incubated with cell-penetrating peptides. Langel, Ulo, ed. Cell-Penetrating Peptides: Methods and Protocols, Vol. 1324. Methods in Molecular Biology, vol. 1324. Springer, pp. 247-259. (10.1007/978-1-4939-2806-4_16)

Sayers, Edward John ORCID: https://orcid.org/0000-0002-2621-1119, Cleal, Kez, Eissa, Noura Gamal, Watson, Peter Duncan ORCID: https://orcid.org/0000-0003-0250-7852 and Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2014. Distal phenylalanine modification for enhancing cellular delivery of fluorophores, proteins and quantum dots by cell penetrating peptides. Journal of Controlled Release 195 , pp. 55-62. 10.1016/j.jconrel.2014.07.055

Kothayer, Hend, Elshanawani, Abdalla A., Abu Kull, Mansour E., El-Sabbagh, Osama I., Shekhar, Malathy P. V., Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 and Westwell, Andrew D. ORCID: https://orcid.org/0000-0002-5166-9236 2013. Design, synthesis and in vitro anticancer evaluation of 4,6-diamino-1,3,5-triazine-2-carbohydrazides and -carboxamides. Biorganic and Medicinal Chemistry Letters 23 (24) , pp. 6886-6889. 10.1016/j.bmcl.2013.09.087

Mart, Robert J. ORCID: https://orcid.org/0000-0003-2196-5840, Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376, Watkins, Catherine Louise, Chappell, Sally Claire, Wiltshire, Marie, Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905, Smith, Paul James and Allemann, Rudolf Konrad ORCID: https://orcid.org/0000-0002-1323-8830 2013. BH3 helix-derived biophotonic nanoswitches regulate cytochrome c release in permeabilised cells. Molecular BioSystems 9 (11) , pp. 2597-2603. 10.1039/c3mb70246d

Hamdy, Rania, Ziedan, Noha, Ali, Samia, El-Sadek, Mohamed, Lashin, Elsaid, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 and Westwell, Andrew D. ORCID: https://orcid.org/0000-0002-5166-9236 2013. Synthesis and evaluation of 3-(benzylthio)-5-(1H-indol-3-yl)-1,2,4-triazol-4-amines as Bcl-2 inhibitory anticancer agents. Biorganic and Medicinal Chemistry Letters 23 (8) , pp. 2391-2394. 10.1016/j.bmcl.2013.02.029

Cleal, Kez, He, Lin, Watson, Peter Duncan ORCID: https://orcid.org/0000-0003-0250-7852 and Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2013. Endocytosis, intracellular traffic and fate of cell penetrating peptide based conjugates and nanoparticles. Current Pharmaceutical Design 19 (16) , pp. 2878-2894. 10.2174/13816128113199990297

Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 and Sayers, Edward John ORCID: https://orcid.org/0000-0002-2621-1119 2012. Cell entry of cell penetrating peptides and tales of tails wagging dogs. Journal of Controlled Release 161 (2) , pp. 582-591. 10.1016/j.jconrel.2012.04.003

Al Soraj, M., He, Lin, Peynshaert, Karen, Cousaert, Julie, Vercauteren, D., Braeckmans, K., De Smedt, S. C. and Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2012. siRNA and pharmacological inhibition of endocytic pathways to characterize the differential role of macropinocytosis and the actin cytoskeleton on cellular uptake of dextran and cationic cell penetrating peptides octaarginine (R8) and HIV-Tat. Journal of Controlled Release 161 (1) , pp. 132-141. 10.1016/j.jconrel.2012.03.015

Bailey, D., Carpenter, E. P., Coker, A., Coker, S., Read, J., Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905, Erskine, P., Aguilar, C. F., Badasso, M., Toldo, L., Rippmann, F., Sanz-Aparicio, J., Albert, A., Blundell, T. L., Roberts, N. B., Wood, S. P. and Cooper, J. B. 2012. An analysis of subdomain orientation, conformational change and disorder in relation to crystal packing of aspartic proteinases. Acta Crystallographica Section D: Biological Crystallography 68 (5) , pp. 541-552. 10.1107/S0907444912004817

Watkins, Catherine Louise, Sayers, Edward John ORCID: https://orcid.org/0000-0002-2621-1119, Allender, Christopher John, Barrow, David Anthony ORCID: https://orcid.org/0000-0003-2096-7262, Fegan, Christopher Daniel ORCID: https://orcid.org/0000-0001-9685-0621, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499 and Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2011. Co-operative membrane disruption between cell-penetrating peptide and cargo: implications for the therapeutic use of the Bcl-2 converter peptide D-NuBCP-9-r8. Molecular Therapy 19 (12) , pp. 2124-2132. 10.1038/mt.2011.175

Vercauteren, Dries, Deschout, Hendrik, Remaut, Katrien, Engbersen, Johan F.J., Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905, Demeester, Jo, De Smedt, Stefaan C. and Braeckmans, Kevin 2011. Dynamic colocalization microscopy to characterize intracellular trafficking of nanomedicines. ACS Nano 5 (10) , pp. 7874-7884. 10.1021/nn2020858

Vercauteren, Dries, Piest, Martin, van der Aa, Leonardus J., Alsoraj, Monerah, Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905, Engbersen, Johan F. J., De Smedt, Stefaan C. and Braeckmans, Kevin 2011. Flotillin-dependent endocytosis and a phagocytosis-like mechanism for cellular internalization of disulfide-based poly(amido amine)/DNA polyplexes. Biomaterials 32 (11) , pp. 3072-3084. 10.1016/j.biomaterials.2010.12.045

Fricke, Thomas, Mart, Robert J. ORCID: https://orcid.org/0000-0003-2196-5840, Watkins, Catherine Louise, Wiltshire, Marie, Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376, Smith, Paul James, Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 and Allemann, Rudolf Konrad ORCID: https://orcid.org/0000-0002-1323-8830 2011. Chemical synthesis of cell-permeable apoptotic peptides from in vivo produced proteins. Bioconjugate Chemistry 22 (9) , pp. 1763-1767. 10.1021/bc200338u

Fricke, Thomas, Mart, Robert J. ORCID: https://orcid.org/0000-0003-2196-5840, Watkins, Catherine Louise, Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 and Allemann, Rudolf Konrad ORCID: https://orcid.org/0000-0002-1323-8830 2010. Click chemistry for the generation of cell permeable apoptotic peptides. Drug Discovery Today 15 (23-24) , p. 1088. 10.1016/j.drudis.2010.09.375

Sweeney, Michele, Watkins, Catherine Louise, Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 and Taggart, Michael J. 2010. Octaarginine mediated delivery of fluorescent cargo to human smooth muscle cells. Drug Discovery Today 15 (23-24) , p. 1085. 10.1016/j.drudis.2010.09.367

Gumbleton, Mark ORCID: https://orcid.org/0000-0002-7386-311X and Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2010. Cellular delivery of therapeutic macromolecules (CDTM) international Symposium 2010: lessons and progress from inter-disciplinary science. Drug Discovery Today 15 (23-24) , pp. 1079-180. 10.1016/j.drudis.2010.10.010

Al-Soraj, Monerah H., Watkins, Catherine Louise, Vercauteren, Dries, De Smedt, Stefaan, Braeckmans, Kevin and Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2010. siRNA versus pharmacological inhibition of endocytic pathways for studying cellular uptake of cell penetrating peptides and other drug delivery vectors. Drug Discovery Today 15 (23-24) , p. 1103. 10.1016/j.drudis.2010.09.411

Vercauteren, Dries, Vandenbroucke, Roosmarijn E., Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905, Rejman, Joanna, Demeester, Joseph, De Smedt, Stefaan C., Sanders, Niek N. and Braeckmans, Kevin 2010. The use of inhibitors to study endocytic pathways of gene carriers: Optimization and pitfalls. Molecular Therapy 18 (3) , pp. 561-569. 10.1038/mt.2009.281

Bruyere, Helene, Westwell, Andrew ORCID: https://orcid.org/0000-0002-5166-9236 and Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2010. Tuning the pH sensitivities of orthoester based compounds for drug delivery applications by simple chemical modification. Bioorganic & Medicinal Chemistry Letters 20 (7) , pp. 2200-2203. 10.1016/j.bmcl.2010.02.035

Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2010. Uptake and intracellular dynamics of proteins internalized by cell-penetrating peptides. Weissig, Volkmar and D'Souza, Gerard G. M., eds. Organelle-Specific Pharmaceutical Nanotechnology, Hoboken, NJ.: John Wiley & Sons, pp. 263-288. (10.1002/9780470875780.ch15)

Watkins, Catherine Louise, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Fegan, Christopher Daniel ORCID: https://orcid.org/0000-0001-9685-0621, Takayama, Kentaro, Nakase, Ikuhiko, Futaki, Shiroh and Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2009. Cellular uptake, distribution and cytotoxicity of the hydrophobic cell penetrating peptide sequence PFVYLI linked to the proapoptotic domain peptide PAD. Journal of Controlled Release 140 (3) , pp. 237-244. 10.1016/j.jconrel.2009.04.028

Hughes, Mary Louise ORCID: https://orcid.org/0000-0001-9723-3975, John, David Neale ORCID: https://orcid.org/0000-0002-4721-6170 and Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2009. Information provided with dispensed medicines: What role does language choice play? A perspective from Wales [Abstract]. International Journal of Pharmacy Practice 17 (S2) , B44-B45. 10.1211/096176709789037128

Hughes, Mary Louise ORCID: https://orcid.org/0000-0001-9723-3975, John, David Neale ORCID: https://orcid.org/0000-0002-4721-6170, Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905, Jones, Elen and Wilkins, Megan Lowri 2009. Language issues in the community pharmacy: a perspective from Wales. International Journal of Pharmacy Practice 17 (3) , pp. 157-163. 10.1211/ijpp.17.03.0006

Hughes, Mary Louise ORCID: https://orcid.org/0000-0001-9723-3975, John, David Neale ORCID: https://orcid.org/0000-0002-4721-6170 and Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2009. Medicines use reviews and language choice. International Journal of Pharmacy Practice 17 (s1) , A41. 10.1211/096176709787640689

Watkins, Catherine Louise, Schmaljohann, Dirk, Futaki, Shiroh and Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2009. Low concentration thresholds of plasma membranes for rapid energy-independent translocation of a cell-penetrating peptide. Biochemical Journal 420 (2) , pp. 179-189. 10.1042/BJ20090042

Jin, J. and Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2009. The pH sensitive probe 5-(and-6)-carboxyl seminaphthorhodafluor is a substrate for the multidrug resistance-related protein MRP1. International Journal of Cancer 124 (1) , pp. 233-238. 10.1002/ijc.23892

Kosuge, Michie., Takeuchi, Toshihide, Nakase, Ikuhiko, Jones, Arwyn ORCID: https://orcid.org/0000-0003-2781-8905 and Futaki, Shiroh 2008. Cellular internalization and distribution of arginine-rich peptides as a function of extracellular peptide concentration, serum, and plasma membrane associated proteoglycans. Bioconjugate Chemistry 19 (3) , pp. 656-664. 10.1021/bc700289w

Jin, J., Pastrello, D., Penning, N. A. and Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2008. Clustering of endocytic organelles in parental and drug-resistant myeloid leukaemia cell lines lacking centrosomally organised microtubule arrays. The International Journal of Biochemistry & Cell Biology 40 (10) , pp. 2240-2252. 10.1016/j.bioce1.2008.03.004

Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2008. Gateways and tools for drug delivery: Endocytic pathways and the cellular dynamics of cell penetrating peptides. International Journal of Pharmaceutics 354 (1-2) , pp. 34-38. 10.1016/j.ijpharm.2007.10.046

Hughes, Mary Louise ORCID: https://orcid.org/0000-0001-9723-3975, John, David Neale ORCID: https://orcid.org/0000-0002-4721-6170 and Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2008. The role of the Welsh language in community pharmacy service provision in Wales. London: Pharmacy Practice Research Trust.

McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X, Pathirana, Ranjith N., Migliore, Marco, Adak, Rina, Luoni, Giovanna maria, Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905, Díez-Torrubia, Alberto, Camarasa, Maria-Jose, Velázquez, Sonsoles, Henson, Geoffrey, Verbeken, Erik, Sienaer, Rebecca, Naesens, Lieve, Snoeck, Robert, Andrei, Graciela and Balzarini, Jan 2007. Preclinical development of bicyclic nucleoside analogues as potent and selective inhibitors of varicella zoster virus. Journal of Antimicrobial Chemotherapy 60 (6) , pp. 1316-1330. 10.1093/jac/dkm376

Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2007. Enclocytic pathways: gateways for intracellular drug delivery [Abstract]. Journal of Pharmacy and Pharmacology 59 (S1) , A72. 10.1211/002235707781850023

Fretz, Marjan M., Penning, Neal Aart, Al-Taei, Saly, Futaki, Shiroh, Takeuchi, Toshihide, Nakase, Ikuhiko, Storm, Gert and Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2007. Temperature-, concentration- and cholesterol-dependent translocation of L- and D-octa-arginine across the plasma and nuclear membrane of CD34+ leukaemia cells. Biochemical Journal 403 (2) , pp. 335-342. 10.1042/BJ20061808

Futaki, S., Nakase, I., Taclokoro, A., Takeuchi, T. and Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2007. Arginine-rich peptides and their internalization mechanisms. Biochemical Society Transactions 35 (4) , pp. 784-787.

Greco, F., Vicent, M. J., Gee, S., Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905, Gee, Julia Margaret Wendy ORCID: https://orcid.org/0000-0001-6483-2015, Nicholson, Robert Ian and Duncan, Ruth 2007. Investigating the mechanism of enhanced cytotoxicity of HPMA copolymer-Dox-AGM in breast cancer cells. Journal of Controlled Release 117 (1) , pp. 28-39. 10.1016/j.jconrel.2006.10.012

Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2007. Macropinocytosis: searching for an endocytic identity and role in the uptake of cell penetrating peptides. Journal of Cellular and Molecular Medicine 11 (4) , pp. 670-684. 10.1111/j.1582-4934.2007.00062.x

Maiti, K. K., Lee, W. S., Takeuchi, T., Watkins, Catherine Louise, Fretz, M., Kim, D. C., Futaki, S., Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905, Kim, K. T. and Chung, S. K. 2007. Guanidine-containing molecular transporters: Sorbitol-based transporters show high intracellular selectivity toward mitochondria. Angewandte Chemie International Edition 46 (31) , pp. 5880-5884. 10.1002/anie.200701346

Manunta, M., Izzo, L., Duncan, Ruth and Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2007. Establishment of subcellular fractionation techniques to monitor the intracellular fate of polymer therapeutics II. Identification of endosomal and lysosomal compartments in HepG2 cells combining single-step subcellular fractionation with fluorescent imaging. Journal of Drug Targeting 15 (1) , pp. 37-50. 10.1080/10611860601010330

Peeters, L., Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905, Demeester, J., De Smedt, S. and Sanders, N. 2007. Post-PEGylated lipoplexes are promising vehicles for gene delivery in RPE cells. Human Gene Therapy 18 (10) , pp. 1046-1047.

Peeters, L., Sanders, N. N., Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905, Demeester, J. and De Smedt, S. C. 2007. Post-pegylated lipoplexes are promising vehicles for gene delivery in RPE cells. Journal of Controlled Release 121 (3) , pp. 208-217. 10.1016/j.jconrel.2007.05.033

Seib, F. P., Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 and Duncan, Ruth 2007. Comparison of the endocytic properties of linear and branched PEIs, and cationic PAMAM dendrimers in B16f10 melanoma cells. Journal of Controlled Release 117 (3) , pp. 291-300. 10.1016/j.jconrel.2006.10.020

Berna, Manuela, Dalzoppo, Daniele, Pasut, Gianfranco, Manunta, Maria, Izzo, Lorella, Jones, Arwyn ORCID: https://orcid.org/0000-0003-2781-8905, Duncan, Ruth and Veronese, Francesco M. 2006. Novel monodisperse PEG-dendrons as new tools for targeted drug delivery: Synthesis, characterisation and cellular uptake. Biomacromolecules 7 (1) , pp. 146-153. 10.1021/bm050480s

Fretz, Marjan Maria, Jin, Jing, Conibere, Robin John, Penning, Neal Aart, Al-Taei, Saly, Storm, Gert, Futaki, Shiroh, Takeuchi, Toshihide, Nakase, Ikuhiko and Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2006. Effects of Na+/H+ exchanger inhibitors on subcellular localisation of endocytic organelles and intracellular dynamics of protein transduction domains HIV-TAT peptide and octaarginine. Journal of Controlled Release 116 (2) , pp. 247-254. 10.1016/j.jconrel.2006.07.009

Al-Taei, Saly, Penning, Neal Aart, Simpson, Jeremy C., Futaki, Shiroh, Takeuchi, Toshihide, Nakase, Ikuhiko and Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2006. Intracellular traffic and fate of protein transduction domains HIV-1 TAT peptide and octaarginine. Implications for their utilization as drug delivery vectors. Bioconjugate Chemistry 17 (1) , pp. 90-100. 10.1021/bc050274h

Seib, Friedrich Philipp, Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 and Duncan, Ruth 2006. Establishment of subcellular fractionation techniques to monitor the intracellular fate of polymer therapeutics I. Differential centrifugation fractionation B16F10 cells and use to study the intracellular fate of HPMA copolymer-doxorubicin. Journal of drug targeting 14 (6) , pp. 375-390. 10.1080/10611860600833955

Hughes, Mary Louise ORCID: https://orcid.org/0000-0001-9723-3975, John, David Neale ORCID: https://orcid.org/0000-0002-4721-6170, Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905, Wilkins, M. L. and Jones, E. H. 2005. Patients' views on use of the Welsh language in community pharmacy: an exploratory study. International Journal of Pharmacy Practice 13 (s1) , R93. 10.1211/096176705777341217/pdf

Hughes, Mary Louise ORCID: https://orcid.org/0000-0001-9723-3975, John, David Neale ORCID: https://orcid.org/0000-0002-4721-6170 and Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2005. Exploring the role of the Welsh language in community pharmacy: the professionals' views. International Journal of Pharmacy Practice 13 (s1) , R94. 10.1211/096176705777341217/pdf

Watson, Peter Duncan ORCID: https://orcid.org/0000-0003-0250-7852, Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 and Stephens, David J. 2005. Intracellular trafficking pathways and drug delivery: fluorescence imaging of living and fixed cells. Advanced Drug Delivery Reviews 57 (1) , pp. 43-61. 10.1016/j.addr.2004.05.003

Simpson, Jeremy C. and Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2005. Early endocytic Rabs: functional prediction to functional characterization. McIlhinney, Jeff and Hooper, Nigel, eds. Biochemical Society Symposia Volume 72: Lipids, Rafts and Traffic, Portland Press, pp. 99-108.

Nakase, Ikuhiko, Niwa, Miki, Takeuchi, Toshihide, Sonomura, Kazuhiro, Ueda, Kunihiro, Simpson, Jeremy C., Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905, Sugiura, Yukio and Futaki, Shiroh 2004. Cellular uptake of arginine-rich peptides: roles for macropinocytosis and actin rearrangement. Molecular Therapy 10 (6) , pp. 1011-22. 10.1016/j.ymthe.2004.08.010

Simpson, Jeremy C., Griffiths, Gareth, Wessling-Resnick, Marianne, Fransen, Jack A. M., Bennett, Holly and Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2004. A role for the small GTPase Rab21 in the early endocytic pathway. Journal of cell science 117 (26) , pp. 6297-6311. 10.1242/jcs.01560

Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905, Gumbleton, Mark ORCID: https://orcid.org/0000-0002-7386-311X and Duncan, Ruth 2003. Understanding endocytic pathways and intracellular trafficking: a prerequisite for effective design of advanced drug delivery systems. Advanced Drug Delivery Reviews 55 (11) , pp. 1353-1367. 10.1016/j.addr.2003.07.002

Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2001. Intracellular drug delivery. Workshop teport from the 28th International Symposium on Controlled Release of Bioactive Materials, San Diego, 23-24 June 2001. Traffic 2 (12) , pp. 917-920. 10.1034/j.1600-0854.2001.21207.x

Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905, Mills, Ian G., Scheidig, Axel J., Alexandrov, Kirill and Clague, Michael J. 1998. Inhibition of endosome fusion by wortmannin persists in the presence of activated rab5. Molecular Biology of the Cell 9 (2) , pp. 323-332. 10.1091/mbc.9.2.323

Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 and Wessling-Resnick, M. 1998. Inhibition of in vitro endosomal vesicle fusion activity by aminoglycoside antibiotics. Journal of Biological Chemistry 273 (39) , pp. 25301-25309. 10.1074/jbc.273.39.25301

Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 and Clague, Michael J. 1997. Regulation of early endosome fusion by phospholipase D activity. Biochemical and Biophysical Research Communications 236 (2) , pp. 285-288. 10.1006/bbrc.1997.6962

Gaffet, P., Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 and Clague, M. J. 1997. Inhibition of calcium-independent mannose 6-phosphate receptor incorporation into trans-Golgi network-derived clathrin-coated vesicles by wortmannin. Journal of Biological Chemistry 272 (39) , pp. 24170-24175. 10.1074/jbc.272.39.24170