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Number of items: 22.

McPhail, Darius K., Alzahrani, Mohammad A.M., Martin, Katie R., Calver, Brian L., Harwood, Adrian J. ORCID: https://orcid.org/0000-0003-3124-5169, MacKeigan, Jeffrey P., Davies, David M. and Tee, Andrew R. ORCID: https://orcid.org/0000-0002-5577-4631 2025. Loss of tuberous sclerosis complex 2 confers inflammation via dysregulation of nuclear factor kappa-light-chain-enhancer of activated B cells. Journal of Inflammation 22 (1) , 38. 10.1186/s12950-025-00464-8
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Tahsin, Tasmia, McPhail, Darius K., Champion, Jesse D., Alzahrani, Mohammad A. M., Hilditch, Madeleine L., Faris-Orr, Alexandre, Calver, Brian L., Cronin, James G., Mareque-Rivas, Juan C., Sexton, Darren W., Hughes, Stephen Fôn, Conlan, Robert Steven, Davies, David Mark and Tee, Andrew R. 2025. Targeting NRF2 and FSP1 to overcome ferroptosis resistance in TSC2-deficient and cancer cells. Cancers 17 (16) , 2714. 10.3390/cancers17162714
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Da'as, Sahar I., Thanassoulas, Angelos, Calver, Brian L., Saleh, Alaaeldin, Abdelrahman, Doua, Hasan, Waseem, Safieh‐Garabedian, Bared, Kontogianni, Iris, Nasrallah, Gheyath K., Nounesis, George, Lai, F. Anthony ORCID: https://orcid.org/0000-0003-2852-8547 and Nomikos, Michail 2024. Divergent biochemical properties and disparate impact of arrhythmogenic calmodulin mutations on zebrafish cardiac function. Journal of Cellular Biochemistry 125 (8) , e30619. 10.1002/jcb.30619
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Thanassoulas, Angelos, Vassilakopoulou, Vyronia, Calver, Brian L., Buntwal, Luke, Smith, Adrian, Lai, Christopher, Kontogianni, Iris, Livaniou, Evangelia, Nounesis, George, Lai, F. Anthony and Nomikos, Michail 2023. Life-threatening arrhythmogenic CaM mutations disrupt CaM binding to a distinct RyR2 CaM-binding pocket. BBA - General Subjects 1867 (4) , 130313. 10.1016/j.bbagen.2023.130313
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Gampala, Silpa, Shah, Fenil, Zhang, Chi, Rhodes, Steven D., Babb, Olivia, Grimard, Michelle, Wireman, Randall S., Rad, Ellie, Calver, Brian, Bai, Ren-Yuan, Staedtke, Verena, Hulsey, Emily L., Saadatzadeh, M. Reza, Pollok, Karen E., Tong, Yan, Smith, Abbi E., Clapp, D. Wade, Tee, Andrew R. ORCID: https://orcid.org/0000-0002-5577-4631, Kelley, Mark R. and Fishel, Melissa L. 2021. Exploring transcriptional regulators Ref-1 and STAT3 as therapeutic targets in malignant peripheral nerve sheath tumours. British Journal of Cancer 124 (9) , pp. 1566-1580. 10.1038/s41416-021-01270-8
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Da'as, Sahar I., Thanassoulas, Angelos, Calver, Brian, Beck, Konrad ORCID: https://orcid.org/0000-0001-5098-9484, Salem, Rola, Saleh, Alaaeldin, Kontogianni, Iris, Al-Maraghi, Ali, Nasrallah, Gheyath K., Safieh-Garabedian, Bared, Toft, Egon, Nounesis, George, Lai, F A ORCID: https://orcid.org/0000-0003-2852-8547 and Nomikos, Michail 2019. Arrhythmogenic calmodulin E105A mutation alters cardiac RyR2 regulation leading to cardiac dysfunction in zebrafish. Annals of the New York Academy of Sciences 1448 (1) , pp. 19-29. 10.1111/nyas.14033
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Daas, Sahar I, Fakhro, Khalid, Thanassoulas, Angelos, Krishnamoorthy, Navaneethakrishnan, Saleh, Alaaeldin, Calver, Brian L, Safiehgarabedian, Bared, Toft, Egon, Nounesis, George, Lai, Anthony and Nomikos, Michail 2018. Hypertrophic cardiomyopathy-linked variants of cardiac myosin binding protein C3 display altered molecular properties and actin interaction. Biochemical Journal 475 (24) , pp. 3933-3948. 10.1042/BCJ20180685
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Calver, Brian 2018. The role of calmodulin in the regulation of calcium signalling proteins in health and disease. PhD Thesis, Cardiff University.
Item availability restricted.
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Nomikos, Michail, Stamatiadis, Panagiotis, Sanders, Jessica Rose, Beck, Konrad ORCID: https://orcid.org/0000-0001-5098-9484, Calver, Brian Lewis, Buntwal, Luke, Lofty, Morgan, Sideratou, Zili, Swann, Karl ORCID: https://orcid.org/0000-0002-4355-1449 and Lai, Francis Anthony ORCID: https://orcid.org/0000-0003-2852-8547 2017. Male infertility-linked point mutation reveals a vital binding role for the C2 domain of sperm PLCζ. Biochemical Journal 474 (6) , pp. 1003-1016. 10.1042/BCJ20161057
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Nomikos, Michail, Thanassoulas, Angelos, Beck, Konrad ORCID: https://orcid.org/0000-0001-5098-9484, Theodoridou, Maria, Kew, Jasmine, Kashir, Junaid, Calver, Brian Lewis, Matthews, Emily, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Sideratou, Zili, Nounesis, George and Lai, Francis Anthony ORCID: https://orcid.org/0000-0003-2852-8547 2016. Mutations in PLCd1 associated with hereditary leukonychia display divergent PIP2 hydrolytic function. FEBS Journal 283 (24) , pp. 4502-4514. 10.1111/febs.13939
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Nomikos, Michail, Sanders, Jessica Rose, Parthimos, Dimitris ORCID: https://orcid.org/0000-0003-3852-323X, Buntwal, Luke, Calver, Brian Lewis, Stamatiadis, Panagiotis, Smith, Adrian, Clue, Matthew, Sideratou, Zili, Swann, Karl ORCID: https://orcid.org/0000-0002-4355-1449 and Lai, Francis Anthony ORCID: https://orcid.org/0000-0003-2852-8547 2015. Essential role of the EF-hand domain in targeting sperm phospholipase Cζ to membrane phosphatidylinositol 4,5-bisphosphate (PIP2). Journal of Biological Chemistry 290 (49) , pp. 29519-29530. 10.1074/jbc.M115.658443
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Vassilakopoulou, Vyronia, Calver, Brian, Thanassoulas, Angelos, Beck, Konrad ORCID: https://orcid.org/0000-0001-5098-9484, Hu, Handan, Buntwal, Luke, Smith, Adrian, Theodoridou, Maria, Kashir, Junaid, Blayney, Lynda, Livaniou, Evangelia, Nounesis, George, Lai, Francis ORCID: https://orcid.org/0000-0003-2852-8547 and Nomikos, Michail 2015. Distinctive malfunctions of calmodulin mutations associated with heart RyR2-mediated arrhythmic disease. Biochimica et Biophysica Acta (BBA) - General Subjects 1850 (11) , pp. 2168-2176. 10.1016/j.bbagen.2015.07.001

Nomikos, Michail, Thanassoulas, Angelos, Beck, Konrad ORCID: https://orcid.org/0000-0001-5098-9484, Vassilakopoulou, Vyronia, Hu, Handan, Calver, Brian Lewis, Theodoridou, Maria, Kashir, Junaid, Blayney, Lynda Mary, Livaniou, Evangelia, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Nounesis, George and Lai, Francis Anthony ORCID: https://orcid.org/0000-0003-2852-8547 2014. Altered RyR2 regulation by the calmodulin F90L mutation associated with idiopathic ventricular fibrillation and early sudden cardiac death. Febs Letters 588 (17) , pp. 2898-2902. 10.1016/j.febslet.2014.07.007

Nomikos, Michail, Theodoridou, Maria, Elgmati, Khalil, Parthimos, Dimitris ORCID: https://orcid.org/0000-0003-3852-323X, Calver, Brian L., Buntwal, Luke, Nounesis, George, Swann, Karl ORCID: https://orcid.org/0000-0002-4355-1449 and Lai, F. Anthony ORCID: https://orcid.org/0000-0003-2852-8547 2014. Human PLCζ exhibits superior fertilization potency over mouse PLCζ in triggering the Ca2+ oscillations required for mammalian oocyte activation. Molecular Human Reproduction 20 (6) , pp. 489-498. 10.1093/molehr/gau011

Theodoridou, Maria, Nomikos, Michail, Parthimos, Dimitris ORCID: https://orcid.org/0000-0003-3852-323X, Gonzalez-Garcia, J., Elgmati, K., Calver, Brian Lewis, Sideratou, Z., Nounesis, G., Swann, Karl ORCID: https://orcid.org/0000-0002-4355-1449 and Lai, Francis Anthony ORCID: https://orcid.org/0000-0003-2852-8547 2013. Chimeras of sperm PLCζ reveal disparate protein domain functions in the generation of intracellular Ca2+ oscillations in mammalian eggs at fertilization. Molecular Human Reproduction 19 (12) , pp. 852-864. 10.1093/molehr/gat070

Nomikos, Michail ORCID: https://orcid.org/0000-0001-9761-6327, Elgmati, Khalil, Theodoridou, Maria, Calver, Brian Lewis, Nounesis, George, Swann, Karl ORCID: https://orcid.org/0000-0002-4355-1449 and Lai, Francis Anthony ORCID: https://orcid.org/0000-0003-2852-8547 2011. Phospholipase C binding to PtdIns(4,5)P2 requires the XY-linker region. Journal of Cell Science 124 (15) , pp. 2582-2590. 10.1242/jcs.083485

Nomikos, Michail, Elgmati, Khalil, Theodoridou, Maria, Calver, Brian Lewis, Cumbes, Bevan ORCID: https://orcid.org/0000-0001-8529-0040, Nounesis, George, Swann, Karl ORCID: https://orcid.org/0000-0002-4355-1449 and Lai, Francis Anthony ORCID: https://orcid.org/0000-0003-2852-8547 2011. Male infertility-linked point mutation disrupts the Ca2+oscillation-inducing and PIP2hydrolysis activity of sperm PLCζ. Biochemical Journal 434 (2) , pp. 211-217. 10.1042/BJ20101772

Nomikos, Michail, Elgmati, Khalil, Theodoridou, Maria, Calver, Brian Lewis, Cumbes, Bevan ORCID: https://orcid.org/0000-0001-8529-0040, Nounesis, George, Swann, Karl ORCID: https://orcid.org/0000-0002-4355-1449 and Lai, Francis Anthony ORCID: https://orcid.org/0000-0003-2852-8547 2011. Male infertility-linked point mutation disrupts the Ca2+ oscillation-inducing and PIP2 hydrolysis activity of sperm PLCζ [Erratum]. The Biochemical Journal 435 (3) , p. 791.

Hubbard, Ruth Eleanor, O'Mahony, Marcella Sinead, Savva, George M., Calver, Brian Lewis and Woodhouse, Kenneth Walter 2009. Inflammation and frailty measures in older people. Journal of Cellular and Molecular Medicine 13 (9b) , pp. 3103-3109. 10.1111/j.1582-4934.2009.00733.x
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Hubbard, Ruth Eleanor, O'Mahony, Marcella Sinead, Calver, Brian Lewis and Woodhouse, Kenneth Walter 2008. Nutrition, inflammation, and leptin levels in aging and frailty. Journal of the American Geriatrics Society 56 (2) , pp. 279-284. 10.1111/j.1532-5415.2007.01548.x

Hubbard, Ruth Eleanor, O'Mahony, Marcella Sinead, Calver, Brian Lewis and Woodhouse, Kenneth Walter 2008. Plasma esterases and inflammation in ageing and frailty. European Journal of Clinical Pharmacology 64 (9) , pp. 895-900. 10.1007/s00228-008-0499-1

White, Susan V., Calver, Brian Lewis, Newsway, Vicky, Wade, R., Patel, Sarju, Bayer, Antony James ORCID: https://orcid.org/0000-0002-7514-248X and O'Mahony, Marcella Sinead 2005. Enzymes of drug metabolism during delirium. Age and Ageing 34 (6) , pp. 603-608. 10.1093/ageing/afi189

This list was generated on Fri Oct 31 15:21:07 2025 GMT.


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