Browse by Current Cardiff authors

Ahmed, Rochelle D., Vitsupakorn, Danoo, Hartwell, Kieran D., Albalawi, Karma, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Watson, Peter D. ORCID: https://orcid.org/0000-0003-0250-7852 and Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2025. Chromophore charge-state switching through copper-dependent homodimerisation of an engineered green fluorescent protein. Chemical Science 10.1039/D5SC06589E

Dolton, Garry, Bulek, Anna, Wall, Aaron, Thomas, Hannah, Hopkins, Jade R, Rius, Cristina, Galloway, Sarah A.E., Whalley, Thomas, Tan, Li Rong, Morin, Theo, Omidvar, Nader, Fuller, Anna, Topley, Katie, Hasan, Samiul, Jain, Shika, D’Souza, Nirupa, Hodges-Hoyland, Tom, Spiller, Owen B. ORCID: https://orcid.org/0000-0002-9117-6911, Kronenberg-Versteeg, Deborah, Szomolay, Barbara ORCID: https://orcid.org/0000-0002-5375-5533, van den Berg, Hugo A., Jones, Lucy C. ORCID: https://orcid.org/0000-0002-3872-4376, Peakman, Mark, Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369 and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 2024. HLA A*24:02-restricted T-cell receptors cross recognise bacterial and preproinsulin peptides in type 1 diabetes. Journal of Clinical Investigation 134 (18) , e164535. 10.1172/JCI164535

Owens, Helen A., Thorburn, Lauren M., Walsby, Elisabeth ORCID: https://orcid.org/0000-0001-8523-5017, Moon, Owen R., Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Sherwani, Subuhi, Tinsley, Caroline L., Rogers, Louise, Cerutti, Camilla, Ridley, Anne J., Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259, Knäuper, Vera ORCID: https://orcid.org/0000-0002-3965-9924 and Ager, Ann ORCID: https://orcid.org/0000-0002-5763-8908 2024. Alzheimer’s disease-associated P460L variant of EphA1 dysregulates receptor activity and blood brain barrier function. Alzheimer's & Dementia: The Journal of the Alzheimer's Association 20 (3) , pp. 2016-2033. 10.1002/alz.13603

Hulin-Curtis, Sarah, Geary, James, MacLachlan, Bruce, Altmann, Danny, Baillon, Laury, Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Greenshields-Watson, Alex, Hesketh, Sophie, Humphreys, Ian ORCID: https://orcid.org/0000-0002-9512-5337, Jones, Ian, Lauder, Sarah, Mason, Georgina, Smart, Kathryn, Scourfield, Oliver, Scott, Jake, Sukhova, Ksenia, Stanton, Richard ORCID: https://orcid.org/0000-0002-6799-1182, Wall, Aaron, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Barclay, Wendy, Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567 2024. A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4+ T cell activation. Cell Reports 43 (6) , 114259. 10.1016/j.celrep.2024.114259

Williamson, Lainey J., Galchenkova, Marina, Best, Hannah L., Bean, Richard J., Munke, Anna, Awel, Salah, Pena, Gisel, Knoska, Juraj, Schubert, Robin, Dörner, Katerina, Park, Hyun-Woo, Bideshi, Dennis K., Henkel, Alessandra, Kremling, Viviane, Klopprogge, Bjarne, Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611, Young, Mark T. ORCID: https://orcid.org/0000-0002-9615-9002, Valerio, Joana, Kloos, Marco, Sikorski, Marcin, Mills, Grant, Bielecki, Johan, Kirkwood, Henry, Kim, Chan, de Wijn, Raphael, Lorenzen, Kristina, Xavier, Paul Lourdu, Rahmani Mashhour, Aida, Gelisio, Luca, Yefanov, Oleksandr, Mancuso, Adrian P., Federici, Brian A., Chapman, Henry N., Crickmore, Neil, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Berry, Colin ORCID: https://orcid.org/0000-0002-9943-548X and Oberthür, Dominik 2023. Structure of the Lysinibacillus sphaericus Tpp49Aa1 pesticidal protein elucidated from natural crystals using MHz-SFX. Proceedings of the National Academy of Sciences 120 (49) , e2203241120. 10.1073/pnas.2203241120

Mundy, Rosie M., Baker, Alexander T. ORCID: https://orcid.org/0000-0001-8232-0531, Bates, Emily A., Cunliffe, Tabitha G., Teijeira Crespo, Alicia, Moses, Elise, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2023. Broad sialic acid usage amongst species D human adenovirus. npj Viruses 1 , 1. 10.1038/s44298-023-00001-5

Chen, Yuan, Mason, Georgina H., Scourfield, D. Oliver, Greenshields-Watson, Alexander, Haigh, Tracey A., Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135, Long, Heather M., Gallimore, Awen M. ORCID: https://orcid.org/0000-0001-6675-7004, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, MacLachlan, Bruce J. and Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567 2023. Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4+ T cell immunity. Cell Reports 42 (8) , 112827. 10.1016/j.celrep.2023.112827

Dolton, Garry, Rius, Cristina, Wall, Aaron, Szomolay, Barbara ORCID: https://orcid.org/0000-0002-5375-5533, Bianchi, Valentina, Galloway, Sarah A.E., Hasan, MD Samiul, Morin, Theo, Caillaud, Marine, Thomas, Hannah L., Theaker, Sarah, Tan, Li Rong, Fuller, Anna, Topley, Katie, Legut, Mateusz, Attaf, Merriem, Hopkins, Jade R., Behiry, Enas, Zabkiewicz, Joanna ORCID: https://orcid.org/0000-0003-0951-3825, Alvares, Caroline ORCID: https://orcid.org/0000-0003-4391-9802, Lloyd, Angharad, Rogers, Amber, Henley, Peter, Fegan, Chris ORCID: https://orcid.org/0000-0001-9685-0621, Ottmann, Oliver ORCID: https://orcid.org/0000-0001-9559-1330, Man, Stephen ORCID: https://orcid.org/0000-0001-9103-1686, Crowther, Michael D., Donia, Marco, Svane, Inge Marie, Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Brown, Paul E., Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369 and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 2023. Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy. Cell 186 (16) , pp. 3333-3349. 10.1016/j.cell.2023.06.020

Best, Hannah L., Williamson, Lainey J., Lipka-Lloyd, Magdalena, Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064, Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369 and Berry, Colin ORCID: https://orcid.org/0000-0002-9943-548X 2022. The crystal structure of Bacillus thuringiensis Tpp80Aa1 and its interaction with galactose-containing glycolipids. Toxins 14 (12) , 863. 10.3390/toxins14120863

Dolton, Garry, Rius, Cristina, Hasan, Md Samiul, Wall, Aaron, Szomolay, Barbara ORCID: https://orcid.org/0000-0002-5375-5533, Behiry, Enas, Whalley, Thomas, Southgate, Joel, Fuller, Anna, Morin, Théo, Topley, Katie, Tan, Li Rong, Goulder, Philip J.R., Spiller, Owen B. ORCID: https://orcid.org/0000-0002-9117-6911, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Jones, Lucy C. ORCID: https://orcid.org/0000-0002-3872-4376, Connor, Thomas R. ORCID: https://orcid.org/0000-0003-2394-6504 and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 2022. Emergence of immune escape at dominant SARS-CoV-2 killer T cell epitope. Cell 185 (16) , pp. 2936-2951. 10.1016/j.cell.2022.07.002

Bates, Emily A., Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Vánová, Jana, Nestic, Davor, Meniel, Valerie S., Koushyar, Sarah, Cunliffe, Tabitha G., Mundy, Rosie M., Moses, Elise, Uusi-Kerttula, Hanni K., Baker, Alexander T. ORCID: https://orcid.org/0000-0001-8232-0531, Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Majhen, Dragomira, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916, Chester, John D. ORCID: https://orcid.org/0000-0002-7830-3840 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2022. Development of a low seroprevalence, αvβ6 integrin selective virotherapy based on human adenovirus type 10. Molecular Therapy - Oncolytics 25 , pp. 43-56. 10.1016/j.omto.2022.03.007

Noby, Nehad, Johnson, Rachel L., Tyzack, Jonathan D., Embaby, Amira M., Saeed, Hesham, Hussein, Ahmed, Khattab, Sherine N., Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369 and Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2022. Structure-guided engineering of a family IV cold-adapted esterase expands its substrate range. International Journal of Molecular Sciences 23 (9) , 4703. 10.3390/ijms23094703

Noby, Nehad, Auhim, Husam Sabah, Winter, Samuel, Worthy, Harley L., Embaby, Amira M., Saeed, Hesham, Hussein, Ahmed, Pudney, Christopher R., Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Wells, Stephen A. and Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2021. Structure and in silico simulations of a cold-active esterase reveals its prime cold-adaptation mechanism. Open Biology 11 (12) , 210182. 10.1098/rsob.210182

Baker, Alexander T., Boyd, Ryan J., Sarkar, Daipayan, Teijeira Crespo, Alicia, Chan, Chun Kit, Bates, Emily, Waraich, Kasim, Vant, John, Wilson, Eric, Truong, Chloe D., Lipka-Lloyd, Magdalena, Fromme, Petra, Vermaas, Josh, Williams, Dewight, Machiesky, LeeAnn, Heurich, Meike ORCID: https://orcid.org/0000-0003-0105-2702, Nagalo, Bolni M., Coughlan, Lynda, Umlauf, Scott, Chiu, Po-Lin, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Cohen, Taylor S., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Singharoy, Abhishek and Borad, Mitesh J. 2021. ChAdOx1 interacts with CAR and PF4 with implications for thrombosis with thrombocytopenia syndrome. Science Advances 7 (49) , eabl8213. 10.1126/sciadv.abl8213

Griffiths, James S., White, P Lewis, Czubala, Magdalena A. ORCID: https://orcid.org/0000-0001-9881-1095, Simonazzi, Elena, Bruno, Mariolina, Thompson, Aiysha, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Gurney, Mark ORCID: https://orcid.org/0000-0003-1119-6638, da Fonseca, Diogo M., Naglik, Julian R., Ingram, Wendy, Wilson, Keith, van de Veerdonk, Frank L., Barnes, Rosemary, Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421 and Orr, Selinda J. 2021. A human Dectin-2 deficiency associated with invasive aspergillosis. Journal of Infectious Diseases 224 (7) , pp. 1219-1224. 10.1093/infdis/jiab145

Man, Stephen ORCID: https://orcid.org/0000-0001-9103-1686, Redman, James E. ORCID: https://orcid.org/0000-0001-5492-2869, Cross, Deborah L., Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Can, Ilona, Davies, Bethan, Hashimdeen, Shaikh Shimaz, Reid, Reiss, Llewellyn-Lacey, Sian, Miners, Kelly L., Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Lissina, Anya, Brown, Paul E., Wooldridge, Linda, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737 and Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369 2021. Synthetic peptides with inadvertent chemical modifications can activate potentially autoreactive T cells. The Journal of Immunology 207 (4) , pp. 1009-1017. 10.4049/jimmunol.2000756

Worthy, Harley L., Williamson, Lainey J., Auhim, Husam Sabah, Leppla, Stephen H., Sastalla, Inka, Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369 and Berry, Colin ORCID: https://orcid.org/0000-0002-9943-548X 2021. The crystal sructure of Bacillus cereus HblL1. Toxins 13 (4) , 253. 10.3390/toxins13040253

Baker, Alexander T. ORCID: https://orcid.org/0000-0001-8232-0531, Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Bates, Emily A., Moses, Elise, Mundy, Rosie M., Marlow, Gareth ORCID: https://orcid.org/0000-0002-7608-9086, Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Bliss, Carly M., Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2021. The fiber knob protein of human adenovirus type 49 mediates highly efficient and promiscuous infection of cancer cell lines using a novel cell entry mechanism. Journal of Virology 95 (4) , e01849-20. 10.1128/JVI.01849-20

Pope, Jacob R. ORCID: https://orcid.org/0000-0001-6478-5378, Johnson, Rachel L., Jamieson, W. David ORCID: https://orcid.org/0000-0001-8260-5211, Worthy, Harley L., Kailasam, Senthilkumar, Ahmed, Rochelle D., Taban, Ismail, Auhim, Husam Sabah, Watkins, Daniel W. ORCID: https://orcid.org/0000-0003-3825-5036, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Castell, Oliver ORCID: https://orcid.org/0000-0002-6059-8062 and Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2021. Association of fluorescent protein pairs and it's significant impact on fluorescence and energy transfer. Advanced Science 8 (1) , 2003167. 10.1002/advs.202003167

Mowbray, N. G., Ansell, J., Horwood, J., Cornish, J., Rizkallah, P. ORCID: https://orcid.org/0000-0002-9290-0369, Parker, A. ORCID: https://orcid.org/0000-0002-9302-1761, Wall, P., Spinelli, A. and Torkington, J. 2020. Safe management of surgical smoke in the age of COVID-19. British Journal of Surgery 107 (11) , pp. 1406-1413. 10.1002/bjs.11679

Bovay, Amandine, Zoete, Vincent, Rizkallah, Pierre J ORCID: https://orcid.org/0000-0002-9290-0369, Beck, Konrad ORCID: https://orcid.org/0000-0001-5098-9484, Delbreil, Philippe, Speiser, Daniel E, Cole, David K ORCID: https://orcid.org/0000-0003-0028-9396 and Fuertes Marraco, Silvia A 2020. Identification of a superagonist variant of the immunodominant Yellow fever virus epitope NS4b214-222 by combinatorial peptide library screening. Molecular Immunology 125 , pp. 43-50. 10.1016/j.molimm.2020.06.025

Greenshields-Watson, Alexander, Attaf, Meriem, MacLachlan, Bruce J., Whalley, Thomas, Rius, Cristina ORCID: https://orcid.org/0000-0002-1896-1649, Wall, Aaron, Lloyd, Angharad, Hughes, Hywel, Strange, Kathryn E., Mason, Georgina H., Schauenburg, Andrea J., Hulin-Curtis, Sarah L. ORCID: https://orcid.org/0000-0003-0889-964X, Geary, James, Chen, Yuan, Lauder, Sarah N., Smart, Kathryn, Vijaykrishna, Dhanasekaran, Grau, Miguel L., Shugay, Mikhail, Andrews, Robert, Dolton, Garry, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Gallimore, Awen M. ORCID: https://orcid.org/0000-0001-6675-7004, Godkin, Andrew J. ORCID: https://orcid.org/0000-0002-1910-7567, Sewell, Andrew J. ORCID: https://orcid.org/0000-0003-3194-3135 and Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396 2020. CD4 + T cells recognize conserved influenza A epitopes through shared patterns of V-Gene usage and complementary biochemical features. Cell Reports 32 (2) , 107885. 10.1016/j.celrep.2020.107885

Holland, Christopher J., Crean, Rory M., Pentier, Johanne M., de Wet, Ben, Lloyd, Angharad, Srikannathasan, Velupillai, Lissin, Nikolai, Lloyd, Katy A., Blicher, Thomas H., Conroy, Paul J., Hock, Miriam, Pengelly, Robert J., Spinner, Thomas E., Cameron, Brian, Potter, Elizabeth A., Jeyanthan, Anitha, Molloy, Peter E., Sami, Malkit, Aleksic, Milos, Liddy, Nathaniel, Robinson, Ross A., Harper, Stephen, Lepore, Marco, Pudney, Chris R., van der Kamp, Marc W., Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Jakobsen, Bent K., Vuidepot, Annelise and Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396 2020. Specificity of bispecific T cell receptors and antibodies targeting peptide-HLA. Journal of Clinical Investigation 130 (5) , 2673–2688. 10.1172/JCI130562

Cresser-Brown, Joel, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Jin, Yi ORCID: https://orcid.org/0000-0002-6927-4371, Roth, Christian, Miller, David J. and Allemann, Rudolf K. ORCID: https://orcid.org/0000-0002-1323-8830 2020. An unexpected co-crystal structure of the calpain PEF(S) domain with Hfq reveals a potential chaperone function of Hfq. Acta Crystallographica Section F: Structural Biology Communications 76 (2) , pp. 81-85. 10.1107/S2053230X20001181

MacLachlan, Bruce J., Dolton, Garry, Papakyriakou, Athanasios, Greenshields-Watson, Alexander, Mason, Georgina H., Schauenburg, Andrea, Besneux, Matthieu, Szomolay, Barbara ORCID: https://orcid.org/0000-0002-5375-5533, Elliott, Tim, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135, Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396 and Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567 2019. Human leukocyte antigen (HLA) class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope. Journal of Biological Chemistry 294 (52) , pp. 20246-20258. 10.1074/jbc.RA119.009437

Worthy, Harley L., Sabah Auhim, Husam, Jamieson, W. David ORCID: https://orcid.org/0000-0001-8260-5211, Pope, Jacob R. ORCID: https://orcid.org/0000-0001-6478-5378, Wall, Aaron, Batchlor, Robert, Johnson, Rachel L., Watkins, Daniel W. ORCID: https://orcid.org/0000-0003-3825-5036, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Castell, Oliver K. ORCID: https://orcid.org/0000-0002-6059-8062 and Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2019. Positive functional synergy of structurally integrated artificial protein dimers assembled by Click chemistry. Communications Chemistry 2 , 83. 10.1038/s42004-019-0185-5

Madura, Florian, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Legut, Mateusz, Holland, Christopher J., Fuller, Anna, Bulek, Anna, Schauenburg, Andrea J., Trimby, Andrew, Hopkins, Jade R., Wells, Stephen A., Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567, Miles, John J., Sami, Malkit, Li, Yi, Liddy, Nathaniel, Jakobsen, Bent K., Loveridge, E. Joel, Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396 and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 2019. TCR-induced alteration of primary MHC peptide anchor residue. European Journal of Immunology 49 (7) , pp. 1052-1066. 10.1002/eji.201948085

Kalvaitis, Mindaugas E., Johnson, Luke A. ORCID: https://orcid.org/0000-0002-6697-6589, Mart, Robert J. ORCID: https://orcid.org/0000-0003-2196-5840, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369 and Allemann, Rudolf K. ORCID: https://orcid.org/0000-0002-1323-8830 2019. A noncanonical chromophore reveals structural rearrangements of the light-oxygen-voltage domain upon photoactivation. Biochemistry 58 (22) , pp. 2608-2616. 10.1021/acs.biochem.9b00255

Scott, Alan F., Cresser-Brown, Joel, Williams, Thomas L., Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Jin, Yi ORCID: https://orcid.org/0000-0002-6927-4371, Luk, Louis Y.-P. ORCID: https://orcid.org/0000-0002-7864-6261 and Allemann, Rudolf K. ORCID: https://orcid.org/0000-0002-1323-8830 2019. Crystal structure and biophysical analysis of furfural detoxifying aldehyde reductase from clostridium beijerinkii. Applied and Environmental Microbiology 10.1128/AEM.00978-19

Galloway, Sarah A. E., Dolton, Garry, Attaf, Meriem, Wall, Aaron, Fuller, Anna, Rius, Cristina, Bianchi, Valentina, Theaker, Sarah, Lloyd, Angharad, Caillaud, Marine E., Svane, Inge Marie, Donia, Marco, Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Szomolay, Barbara ORCID: https://orcid.org/0000-0002-5375-5533, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369 and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 2019. Peptide super-agonist enhances T-cell responses to melanoma. Frontiers in Immunology 10 , 319. 10.3389/fimmu.2019.00319

Baker, Alexander T. ORCID: https://orcid.org/0000-0001-8232-0531, Greenshields-Watson, Alexander, Coughlan, Lynda, Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Uusi-Kerttula, Hanni, Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2019. Diversity within the adenovirus fiber knob hypervariable loops influences primary receptor interactions. Nature Communications 10 , 741. 10.1038/s41467-019-08599-y

Uusi-Kerttula, Hanni, Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Thompson, Jill M., Wongthida, Phonphimon, Evgin, Laura, Shim, Kevin G., Bradshaw, Angela, Baker, Alexander T. ORCID: https://orcid.org/0000-0001-8232-0531, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Jones, Rachel, Hanna, Louise, Hudson, Emma, Vile, Richard, Chester, John D. ORCID: https://orcid.org/0000-0002-7830-3840 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2018. Ad5NULL-A20 - a tropism-modified, αvβ6 integrin-selective oncolytic adenovirus for epithelial ovarian cancer therapies. Clinical Cancer Research 24 (17) , pp. 4215-4224. 10.1158/1078-0432.CCR-18-1089

Tungatt, Katie, Dolton, Garry, Morgan, Sophie B., Attaf, Meriem, Fuller, Anna, Whalley, Thomas, Hemmink, Johanneke D., Porter, Emily, Szomolay, Barbara ORCID: https://orcid.org/0000-0002-5375-5533, Montoya, Maria, Hammond, John A., Miles, John J., Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Townsend, Alain, Bailey, Mick, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Charleston, Bryan, Tchilian, Elma and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 2018. Induction of influenza-specific local CD8 T-cells in the respiratory tract after aerosol delivery of vaccine antigen or virus in the Babraham inbred pig. PLoS Pathogens 14 (5) , e1007017. 10.1371/journal.ppat.1007017

Holland, Christopher J., MacLachlan, Bruce J., Bianchi, Valentina, Hesketh, Sophie J., Morgan, Richard, Vickery, Owen, Bulek, Anna M., Fuller, Anna, Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Wells, Stephen and Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396 2018. In silico and structural analyses demonstrate that intrinsic protein motions guide T cell receptor complementarity determining region loop flexibility. Frontiers in Immunology 9 , 674. 10.3389/fimmu.2018.00674

Miles, John J., Tan, Mai Ping, Dolton, Garry, Edwards, Emily S. J. ORCID: https://orcid.org/0000-0002-0240-4370, Galloway, Sarah A. E., Laugel, Bruno, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Makinde, Julia, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Matthews, Katherine K., Watkins, Thomas S., Tungatt, Katie, Wong, Yide, Lee, Han Siean, Clark, Richard J., Pentier, Johanne M., Attaf, Meriem, Lissina, Anya, Ager, Ann ORCID: https://orcid.org/0000-0002-5763-8908, Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Gras, Stephanie, Rossjohn, Jamie ORCID: https://orcid.org/0000-0002-2020-7522, Burrows, Scott R., Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737 and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 2018. Peptide mimic for influenza vaccination using nonnatural combinatorial chemistry. Journal of Clinical Investigation 128 (4) , pp. 1569-1580. 10.1172/JCI91512

Bovay, Amandine, Zoete, Vincent, Dolton, Garry, Bulek, Anna M., Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Fuller, Anna, Beck, Konrad ORCID: https://orcid.org/0000-0001-5098-9484, Michielin, Olivier, Speiser, Daniel E., Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 and Fuertes Marraco, Silvia A. 2018. T cell receptor alpha variable 12-2 bias in the immunodominant response to Yellow fever virus. European Journal of Immunology 48 (2) , pp. 258-272. 10.1002/eji.201747082

Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Fuller, Anna, Dolton, Garry, Zervoudi, Efthalia, Legut, Mateusz, Miles, Kim, Blanchfield, Lori, Madura, Florian, Holland, Christopher J., Bulek, Anna M., Bridgeman, John S., Miles, John J., Schauenburg, Andrea J. A., Beck, Konrad ORCID: https://orcid.org/0000-0001-5098-9484, Evavold, Brian D., Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369 and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 2017. Dual molecular mechanisms govern escape at immunodominant HLA A2-restricted HIV epitope. Frontiers in Immunology 8 , 1503. 10.3389/fimmu.2017.01503

MacLachlan, Bruce J., Greenshields-Watson, Alexander, Mason, Georgina H., Schauenburg, Andrea J., Bianchi, Valentina, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135, Fuller, Anna and Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396 2017. Using X-ray crystallography, biophysics, and functional assays to determine the mechanisms governing T-cell receptor recognition of cancer antigens. Journal of Visualized Experiments (120) , e54991. 10.3791/54991

Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, van den Berg, Hugo A., Lloyd, Angharad, Crowther, Michael D., Beck, Konrad ORCID: https://orcid.org/0000-0001-5098-9484, Ekeruche-Makinde, Julia, Miles, John J., Bulek, Anna M., Dolton, Garry, Schauenburg, Andrea J., Wall, Aaron, Fuller, Anna, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Laugel, Bruno, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Wooldridge, Linda and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 2017. Structural mechanism underpinning cross-reactivity of a CD8+ T-cell clone that recognises a peptide derived from human telomerase reverse transcriptase. Journal of Biological Chemistry 292 (3) , pp. 802-813. 10.1074/jbc.M116.741603

Nomikos, Michail, Thanassoulas, Angelos, Beck, Konrad ORCID: https://orcid.org/0000-0001-5098-9484, Theodoridou, Maria, Kew, Jasmine, Kashir, Junaid, Calver, Brian Lewis, Matthews, Emily, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Sideratou, Zili, Nounesis, George and Lai, Francis Anthony ORCID: https://orcid.org/0000-0003-2852-8547 2016. Mutations in PLCd1 associated with hereditary leukonychia display divergent PIP2 hydrolytic function. FEBS Journal 283 (24) , pp. 4502-4514. 10.1111/febs.13939

Hartley, Andrew M., Worthy, Harley L., Reddington, Samuel C., Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369 and Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2016. Molecular basis for functional switching of GFP by two disparate non-native post-translational modifications of a phenyl azide reaction handle. Chemical Science 7 (10) , pp. 6484-6491. 10.1039/C6SC00944A

Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Bulek, Anna M., Dolton, Garry, Schauenberg, Andrea J., Szomolay, Barbara ORCID: https://orcid.org/0000-0002-5375-5533, Rittase, William, Trimby, Andrew, Jothikumar, Prithiviraj, Fuller, Anna, Skowera, Ania, Rossjohn, Jamie ORCID: https://orcid.org/0000-0002-2020-7522, Zhu, Cheng, Miles, John J., Peakman, Mark, Wooldridge, Linda, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369 and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 2016. Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity. Journal of Clinical Investigation 126 (6) , pp. 2191-2204. 10.1172/JCI85679

Bianchi, Valentina, Bulek, Anna, Fuller, Anna, Lloyd, Angharad, Attaf, Meriem, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Dolton, Garry, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 and Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396 2016. A molecular switch abrogates glycoprotein 100 (gp100) T-cell Receptor (TCR) targeting of a human melanoma antigen. Journal of Biological Chemistry 291 (17) , pp. 8951-8959. 10.1074/jbc.M115.707414

Raman, Marine C. C., Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Simmons, Ruth, Donnellan, Zoe, Dukes, Joseph, Bossi, Giovanna, Le Provost, Gabrielle S., Todorov, Penio, Baston, Emma, Hickman, Emma, Mahon, Tara, Hassan, Namir, Vuidepot, Annelise, Sami, Malkit, Cole, David ORCID: https://orcid.org/0000-0003-0028-9396 and Jakobsen, Bent K. 2016. Direct molecular mimicry enables off-target cardiovascular toxicity by an enhanced affinity TCR designed for cancer immunotherapy. Scientific Reports 6 , 18851. 10.1038/srep18851

Adams, S.E., Robinson, E.J., Miller, David James, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X and Allemann, Rudolf Konrad ORCID: https://orcid.org/0000-0002-1323-8830 2015. Conformationally restricted calpain inhibitors. Chemical Science 6 (12) , pp. 6865-6871. 10.1039/c5sc01158b

Motozono, Chihiro, Pearson, James A. ORCID: https://orcid.org/0000-0002-2867-2269, De Leenheer, Evy, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Beck, Konrad ORCID: https://orcid.org/0000-0001-5098-9484, Trimby, Andrew, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396 2015. Distortion of the major histocompatibility complex class I binding groove to accommodate an insulin-derived 10-Mer peptide. Journal of Biological Chemistry 290 (31) , pp. 18924-18933. 10.1074/jbc.M114.622522

Reid, Reiss, Redman, James Edward ORCID: https://orcid.org/0000-0001-5492-2869, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Fegan, Christopher Daniel ORCID: https://orcid.org/0000-0001-9685-0621, Pepper, Christopher John and Man, Stephen Tzekwung ORCID: https://orcid.org/0000-0001-9103-1686 2015. CD8+ T-cell recognition of a synthetic epitope formed by t-butyl modification. Immunology 144 (3) , pp. 495-505. 10.1111/imm.12398

Madura, Florian, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Holland, Christopher J., Fuller, Anna, Bulek, Anna Marta, Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567, Schauenburg, Andrea J., Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396 and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 2015. Structural basis for ineffective T-cell responses to MHC anchor residue-improved 'heteroclitic' peptides. European Journal of Immunology 45 (2) , pp. 584-591. 10.1002/eji.201445114

Reddington, Samuel C., Driezis, Sarunas, Hartley, Andrew M., Watson, Peter Duncan ORCID: https://orcid.org/0000-0003-0250-7852, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369 and Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2015. Genetically encoded phenyl azide photochemistry drives positive and negative functional modulation of a red fluorescent protein. RSC Advances 5 (95) , pp. 77734-77738. 10.1039/C5RA13552D

Kløverpris, Henrik N., Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Fuller, Anna, Carlson, Jonathan, Beck, Konrad ORCID: https://orcid.org/0000-0001-5098-9484, Schauenburg, Andrea J. A., Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Buus, Søren, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 and Goulder, Philip 2015. A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape. Retrovirology 12 (1) , 20. 10.1186/s12977-015-0149-5

Adams, Sarah Elizabeth, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Miller, David James, Robinson, Emma J., Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X and Allemann, Rudolf Konrad ORCID: https://orcid.org/0000-0002-1323-8830 2014. The structural basis of differential inhibition of human calpain by indole and phenyl α--mercaptoacrylic acids. Journal of Structural Biology 187 (3) , pp. 236-241. 10.1016/j.jsb.2014.07.004

Nomikos, Michail, Thanassoulas, Angelos, Beck, Konrad ORCID: https://orcid.org/0000-0001-5098-9484, Vassilakopoulou, Vyronia, Hu, Handan, Calver, Brian Lewis, Theodoridou, Maria, Kashir, Junaid, Blayney, Lynda Mary, Livaniou, Evangelia, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Nounesis, George and Lai, Francis Anthony ORCID: https://orcid.org/0000-0003-2852-8547 2014. Altered RyR2 regulation by the calmodulin F90L mutation associated with idiopathic ventricular fibrillation and early sudden cardiac death. Febs Letters 588 (17) , pp. 2898-2902. 10.1016/j.febslet.2014.07.007

Arpino, James Alexander Joseph, Reddington, Samuel C., Halliwell, Lisa Marie, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369 and Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2014. Random single amino acid deletion sampling unveils structural tolerance and the benefits of helical registry shift on GFP folding and structure. Structure 22 (6) , pp. 889-898. 10.1016/j.str.2014.03.014

Motozono, Chihiro, Kuse, N, Sun, X., Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Fuller, Anna, Oka, S., Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 and Takiguchi, M. 2014. Molecular basis of a dominant T cell response to an HIV reverse transcriptase 8-mer epitope presented by the protective allele HLA-B*51:01. The Journal of Immunology 192 (7) , pp. 3428-3434. 10.4049/jimmunol.1302667

Arpino, James Alexander Joseph, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369 and Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2014. Structural and dynamic changes associated with beneficial engineered single-amino-acid deletion mutations in enhanced green fluorescent protein. Acta Crystallographica Section D Biological Crystallography 70 (8) , pp. 2152-2162. 10.1107/S139900471401267X

Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Sami, Malkit, Scott, David, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Borbulevych, Oleg Y., Todorov, Penio T., Moysey, Ruth K., Jakobsen, Bent K., Boulter, Jonathan M., Baker, Brian M. and Li, Yi 2013. Increased peptide contacts govern high affinity binding of a modified TCR whilst maintaining a native pMHC docking mode. Frontiers in Immunology 4 , 168. 10.3389/fimmu.2013.00168

Madura, Florian, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Miles, Kim Michelle, Holland, Christopher J., Bulek, Anna Marta, Fuller, Anna, Schauenburg, Andrea J. A., Miles, John James, Liddy, Nathaniel, Sami, M., Li, Y., Hossain, M., Baker, B. M., Jakobsen, B. K., Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 and Cole, David ORCID: https://orcid.org/0000-0003-0028-9396 2013. T-cell receptor specificity maintained by altered thermodynamics. Journal of Biological Chemistry 288 (26) , pp. 18766-18775. 10.1074/jbc.M113.464560

Reddington, Samuel C., Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Watson, Peter Duncan ORCID: https://orcid.org/0000-0003-0250-7852, Pearson, Rachel, Tippmann, Eric Michael and Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2013. Different photochemical events of a genetically encoded phenyl azide define and modulate GFP fluorescence. Angewandte Chemie - International Edition 52 (23) , pp. 5974-5977. 10.1002/anie.201301490

Eukeruche-Makinde, Julia, Miles, John J., Van Den Berg, Hugo A., Skowera, Ania, Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Dolton, Garry Michael, Schauenburg, Andrea, Tan, Mai Ping, Pentier, Johanne, Llewellyn-Lacey, Sian, Miles, Kim M., Bulek, Anna, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Dockree, Tamsin, Trimby, Andrew R., Bailey, Mick, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Rossjohn, Jamie ORCID: https://orcid.org/0000-0002-2020-7522, Peakman, Mark, Burrows, Scott, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 and Wooldridge, Linda 2013. Peptide length determines the outcome of TCR/peptide-MHCI engagement. Blood -New York- 121 (7) , pp. 1112-1123. 10.1182/blood-2012-06-437202

Ekeruche, Julia, Miles, John James, van den Berg, Hugo A., Skowera, Ania, Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Dolton, Garry Michael, Schauenburg, Andrea J. A., Tan, Mai Ping, Pentier, Johanne, Llewellyn-Lacey, Sian, Miles, Kim Michelle, Bulek, Anna Marta, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Williams, Tamsin, Trimby, Andrew R., Bailey, Mick, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Rossjohn, Jamie ORCID: https://orcid.org/0000-0002-2020-7522, Peakman, Mark, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Burrows, Scott R., Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 and Wooldridge, Linda 2013. Peptide length determines the outcome of TCR/peptide-MHCI engagement. Blood 121 (7) , pp. 1112-1123. 10.1182/blood-2012-06-437202

Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Miles, Kim Michelle, Madura, Florian, Holland, Christopher J., Schauenburg, Andrea J. A., Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567, Bulek, Anna Marta, Fuller, Anna, Akpovwa, Hephzibah, Pymm, Phillip G., Liddy, N., Sami, M., Li, Y., Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Jakobsen, B. K. and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 2013. T-cell Receptor (TCR)-Peptide Specificity Overrides Affinity-enhancing TCR-Major Histocompatibility Complex Interactions. Journal of Biological Chemistry 289 (2) , pp. 628-638. 10.1074/jbc.M113.522110

Reddington, Samuel C., Watson, Peter Duncan ORCID: https://orcid.org/0000-0003-0250-7852, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Tippmann, Eric Michael and Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2013. Genetically encoding phenyl azide chemistry: new uses and ideas for classical biochemistry. Biochemical Society Transactions 41 (5) , pp. 1177-1182. 10.1042/BST20130094

Ekeruche-Makinde, Julia, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Edwards, Emily S. J. ORCID: https://orcid.org/0000-0002-0240-4370, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Miles, John J., Matthews, Katherine K., Fuller, Anna, Lloyd, Katy A., Madura, Florian, Dolton, Garry M., Pentier, Johanne, Lissina, Anna, Gostick, Emma, Baxter, Tiffany K., Baker, Brian M., Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Wooldridge, Linda and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 2012. T-cell receptor-optimized peptide skewing of the T-cell repertoire can enhance antigen targeting. Journal of Biological Chemistry 287 (44) , pp. 37269-37281. 10.1074/jbc.M112.386409

Ekeruche, Julia, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Edwards, Emily S. J. ORCID: https://orcid.org/0000-0002-0240-4370, Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Miles, John James, Matthews, Katherine K., Fuller, Anna, Lloyd, Katy A., Madura, Florian, Dolton, Garry Michael, Pentier, Johanne, Lissina, Anna, Gostick, Emma, Baxter, Tiffany K., Baker, Brian M., Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Wooldridge, Linda and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 2012. T-cell receptor-optimized peptide skewing of the T-cell repertoire can enhance antigen targeting. Journal of Biological Chemistry 287 (44) , pp. 37269-37281. 10.1074/jbc.M112.386409

Holland, Christopher J., Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Vollers, Sabrina, Calvo-Calle, J. Mauricio, Madura, Florian, Fuller, Anna, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135, Stern, Lawrence J., Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567 and Cole, David ORCID: https://orcid.org/0000-0003-0028-9396 2012. Minimal conformational plasticity enables TCR cross-reactivity to different MHC class II heterodimers. Scientific Reports 2 , 629. 10.1038/srep00629

Bulek, Anna Marta, Madura, Florian, Fuller, Anna, Holland, Christopher J., Schauenburg, Andrea J. A., Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369 and Cole, David ORCID: https://orcid.org/0000-0003-0028-9396 2012. TCR/pMHC optimized protein crystallization screen. Journal of Immunological Methods 382 (1-2) , pp. 203-210. 10.1016/j.jim.2012.06.007

Yang, Sihai, Lin, Xiang, Lewis, William, Suyetin, Mikhail, Bichoutskaia, Elena, Parker, Julia E., Tang, Chiu C., Allan, David R., Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Hubberstey, Peter, Champness, Neil R., Thomas, K. Mark, Blake, Alexander J. and Schröder, Martin 2012. A partially interpenetrated metal-organic framework for selective hysteretic sorption of carbon dioxide. Nature Materials 11 (8) , pp. 710-716. 10.1038/nmat3343

Bulek, Anna, Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Skowera, Ania, Dolton, Garry, Gras, Stephanie, Madura, Florian, Fuller, Anna, Miles, John, Gostick, Emma, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Drijfhout, Jan W, Knight, Robin R, Huang, Guo C, Lissin, Nikolai, Molloy, Peter E, Wooldridge, Linda, Jakobsen, Bent K, Rossjohn, Jamie ORCID: https://orcid.org/0000-0002-2020-7522, Peakman, Mark, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369 and Sewell, Andrew ORCID: https://orcid.org/0000-0003-3194-3135 2012. Structural basis for the killing of human beta cells by CD8+ T cells in type 1 diabetes. Nature Immunology 13 (3) , pp. 283-289. 10.1038/ni.2206

Bulek, Anna Marta, Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Skowera, Ania, Dolton, Garry Michael, Gras, Stephanie, Madura, Florian, Fuller, Anna, Miles, John James, Gostick, Emma, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Drijfhout, Jan W., Knight, Robin R., Huang, Guo C., Lissin, Nikolai, Molloy, Peter E., Wooldridge, Linda, Jakobsen, Bent K., Rossjohn, Jamie, Peakman, Mark, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369 and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 2012. Structural basis for the killing of human beta cells by CD8+ T cells in type 1 diabetes. Nature Immunology 13 (3) , pp. 283-289. 10.1038/ni.2206

Tadesse, Haregewine, Blake, Alexander J., Champness, Neil R., Warren, John E., Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369 and Licence, Peter 2012. Supramolecular architectures of symmetrical dicationic ionic liquid based systems. Crystengcomm 14 (15) , pp. 4886-4893. 10.1039/c2ce25106j

Arpino, James, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369 and Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2012. Crystal structure of enhanced green fluorescent protein to 1.35 Å resolution reveals alternative conformations for Glu222. PLoS ONE 7 (10) , e47132. 10.1371/journal.pone.0047132

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Ronson, Tanya K., Carruthers, Christopher, Fisher, Julie, Brotin, Thierry, Harding, Lindsay P., Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369 and Hardie, Michaele J. 2010. Tripodal 4-pyridyl-derived host ligands and their metallo-supramolecular chemistry: stella octangula and bowl-shaped assemblies. Inorganic Chemistry -American Chemical Society- 49 (2) , pp. 675-685. 10.1021/ic901972h

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