ORCA
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Up a levelNumber of items: 10.
Chiriches, Claudia  ORCID: https://orcid.org/0000-0003-3758-1892, Nicolaisen, Nathalie, Wieske, Maria, Elhaddad, Heba, Mehmetbeyoglu, Ecmel, Alvares, Caroline ORCID: https://orcid.org/0000-0003-4391-9802, Becher, Dörte, Hole, Paul, Ottmann, Oliver Gerhard ORCID: https://orcid.org/0000-0001-9559-1330 and Ruthardt, Martin ORCID: https://orcid.org/0000-0003-1021-3811
2022.
Understanding a high-risk acute myeloid leukemia by analyzing the interactome of its major driver mutation.
PLoS Genetics
18
(10)
, e1010463.
10.1371/journal.pgen.1010463
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| Jones, Nicholas, Vincent, Emma E., Felix, Lindsey C., Cronin, James G., Scott, Louis M., Hole, Paul S., Lacy, Paige and Thornton, Catherine A. 2020. Interleukin-5 drives glycolysis and reactive oxygen species-dependent citric acid cycling by eosinophils. Allergy 75 (6) , pp. 1361-1370. 10.1111/all.14158 |
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Robinson, Andrew J., Hopkins, Goitseone L., Rastogi, Namrata, Hodges, Marie, Doyle, Michelle, Davies, Sara, Hole, Paul S., Omidvar, Nader, Darley, Richard L. ORCID: https://orcid.org/0000-0003-0879-0724 and Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976
2020.
Reactive oxygen species drive proliferation in acute myeloid leukemia via the glycolytic regulator PFKFB3.
Cancer Research
80
(5)
, pp. 937-949.
10.1158/0008-5472.CAN-19-1920
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| Wadley, Alex J., Morgan, Rhys G., Heesom, Kate J., Hole, Paul S. and Coles, Steven J. 2018. Detecting intracellular thiol redox state in leukaemia and heterogeneous immune cell populations: An optimised protocol for digital flow cytometers. MethodsX 5 , pp. 1473-1483. 10.1016/j.mex.2018.10.013 |
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Khan, Naeem, Hills, Robert ORCID: https://orcid.org/0000-0003-0166-0062, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Steadman, Lora, Qureshi, Ushna, Rector, Jerrold L., Bradbury, Charlotte, Russell, Nigel H., Vyas, Paresh, Burnett, Alan K., Grimwade, David, Hole, Paul and Freeman, Sylvie D.
2016.
Normal hematopoietic progenitor subsets have distinct reactive oxygen species, BCl2 and cell-cycle profiles that are decoupled from maturation in acute myeloid leukemia.
PLOS ONE
11
(9)
, e0163291.
10.1371/journal.pone.0163291
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Agathanggelou, A., Weston, V. J., Perry, T., Davies, N. J., Skowronska, A., Payne, D. T., Fossey, J. S., Oldreive, C. E., Wei, W., Pratt, G., Parry, H., Oscier, D., Coles, Steven, Hole, Paul Spencer, Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724, McMahon, M., Hayes, J. D., Moss, P., Stewart, G., Taylor, A. M. R. and Stankovic, T.
2015.
Targeting the ataxia telangiectasia mutated-null phenotype in chronic lymphocytic leukemia with pro-oxidants.
Haematologica
100
(8)
, pp. 1076-1085.
10.3324/haematol.2014.115170
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Hole, Paul Spencer, Zabkiewicz, Joanna ORCID: https://orcid.org/0000-0003-0951-3825, Munje, Chinmay, Newton, Zarabeth, Pearn, Lorna, White, Paul Charles ORCID: https://orcid.org/0000-0002-6562-4696, Marquez, Nuria, Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062, Burnett, Alan Kenneth, Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724
2013.
Overproduction of NOX-derived ROS in AML promotes proliferation and is associated with defective oxidative stress signaling.
Blood
122
(19)
, pp. 3322-3330.
10.1182/blood-2013-04-491944
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Hole, Paul Spencer, Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 and Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976
2011.
Do reactive oxygen species play a role in myeloid leukemias?
Blood
117
(22)
, pp. 5816-5826.
10.1182/blood-2011-01-326025
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Hole, Paul Spencer, Pearn, Lorna, Tonks, Amanda Jayne ORCID: https://orcid.org/0000-0002-6073-4976, James, Philip Eurig, Burnett, Alan Kenneth, Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 and Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976
2010.
Ras-induced reactive oxygen species promote growth factor-independent proliferation in human CD34+ hematopoietic progenitor cells.
Blood
115
(6)
, pp. 1238-1246.
10.1182/blood-2009-06-222869
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Hole, Paul Spencer
2010.
Role of reactive oxygen species in ras-mediated leukaemogenesis.
PhD Thesis,
Cardiff University.
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