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Varley, Melanie ORCID: https://orcid.org/0000-0002-5702-9205, Euden, Joanne ORCID: https://orcid.org/0000-0002-2844-6878, Adams, Richard ORCID: https://orcid.org/0000-0003-3915-7243, Barnes, Eleanor, Bodman, Craig, Choy, Ernest ORCID: https://orcid.org/0000-0003-4459-8609, Cicconi, Paola, Dagley, Vivien, Ewer, Katie, Griffin, Sian, Harris, Debbie ORCID: https://orcid.org/0000-0002-7073-7724, Hill, Adrian, Hood, Kerenza ORCID: https://orcid.org/0000-0002-5268-8631, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Pringle, Shirley, Porter, Catherine, Ottensmeier, Christian H, Raisanen, Lawrence, Ray, Ruby, Tangney, Rebecca, Wilson, Keith, Nixon, Lisette Sheena ORCID: https://orcid.org/0000-0002-1270-6970, Thomas-Jones, Emma ORCID: https://orcid.org/0000-0001-7716-2786 and Tuthill, Mark 2025. Adaptive clinical trial of AZD7442 and SARS-CoV-2 vaccination in immunosuppressed patients highly vulnerable to infection with SARS-CoV-2 virus (RAPID-PROTECTION): protocol for a multicentre, interventional open-label, randomised controlled trial. BMJ Open 15 (1) , e084345. 10.1136/bmjopen-2024-084345
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Versluis, Jurjen, Metzner, Marlen, Wang, Ariel, Gradowska, Patrycja, Thomas, Abin ORCID: https://orcid.org/0000-0002-8283-6762, Jakobsen, Niels Asger, Kennedy, Alison, Moore, Rachel, Boertjes, Emma, Vonk, Christian M., Kavelaars, Francois G., Rijken, Melissa, Gilkes, Amanda, Schwab, Claire, Beverloo, H. Berna, Manz, Markus, Visser, Otto, Van Elssen, Catharina H.M.J., de Weerdt, Okke, Tick, Lidwine W., Biemond, Bart J., Vekemans, Marie-Christiane, Freeman, Sylvie D., Harrison, Christine J., Cook, Jonathan A., Dennis, Mike, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Thomas, Ian, Craddock, Charles, Ossenkoppele, Gert J., Löwenberg, Bob, Russell, Nigel, Valk, Peter J.M. and Vyas, Paresh 2024. Risk stratification in older intensively treated patients with AML. Journal of Clinical Oncology 42 (34) , pp. 4084-4094. 10.1200/JCO.23.02631
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Russell, Nigel H., Thomas, Abin ORCID: https://orcid.org/0000-0002-8283-6762, Hills, Robert K., Thomas, Ian, Gilkes, Amanda, Marquez Almuina, Nuria, Burns, Sarah, Marsh, Lucy, Vyas, Paresh, Metzner, Marlen, McCarthy, Nicholas, Andrew, Georgia, Byrne, Jennifer, Sellar, Rob S., Kelly, Richard, Cahalin, Paul, Malthe Overgaard, Ulrik, Mehta, Priyanka, Dennis, Mike, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441 and Freeman, Sylvie D. 2024. Treatment intensification with either fludarabine, AraC, G-CSF and idarubicin, or cladribine plus daunorubicin and AraC on the basis of residual disease status in older patients With AML: Results From the NCRI AML18 Trial. Journal of Clinical Oncology 10.1200/JCO.24.00259
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Russell, Nigel H., Wilhelm-Benartzi, Charlotte ORCID: https://orcid.org/0000-0003-4927-6158, Othman, Jad, Dillon, Richard, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Batten, Leona M., Canham, Joanna ORCID: https://orcid.org/0000-0003-3482-0990, Hinson, Emily L., Betteridge, Sophie, Overgaard, Ulrik Malthe, Gilkes, Amanda, Potter, Nicola, Mehta, Priyanka, Kottaridis, Panagiotis, Cavenagh, Jamie, Hemmaway, Claire, Arnold, Claire, Freeman, Sylvie D., Dennis, Mike, Kallenbach, Maria, Severinsen, Marianne, Holm, Mette, Maxwell Norgaard, Jan, Beier Ommen, Hans, Culligan, Dominic, Tighe, Jane, Craig, Jenny, Crawley, Charles, Krishnamurthy, Pramila, Sadik, Walid, Smith, Jeffery, Dasgupta, Ranjit, Berkhan, Leanne, Bowett, Peter, Doocey, Richard, Emmett, Shannon, Hawkins, Timothy, Patton, Nigel, Pemberton, Lucy, Milne, Alison, Roy, Ashok, Simpson, Sylwia, Arnold, Claire, Cuthbert, Robert, Finnegan, Damian, Francis McMullin, Mary, Pechey, Victoria, Lovell, Richard, Milligan, Donald, Paneesha, Shankara, Cahalin, Paul, Kelsey, P., Ackroyd, Sam, Wiliams, Adrian, Evely, Roger, Marks, David, Mehta, Priyanka, Fletcher, Andrew, Al-Ani, Maryam, Ahmed, Khalil, Lush, Richard, Rye, Adam, Cutting, Robert, Fletcher, Andrew, Welch, Emma, Wodzinski, Mark, Butler, Andrew, Fernyhough, Liam, Ganly, Peter, Gibbons, Steve, Smith, Mark, Spearing, Ruth, Peniket, Andy, Hatcliffe, Faye, Patel, Amit, Lindsay, Kathrine, Brearton, Gillian, Tuegar, Salah, Gandhi Anna Cowley, S., Copplestone, Adrian, Hunter, Hannah, Medd, Patrick, Nokes, Tim, Rule, Simon, Thomas, Wayne, Cutting, Robert, Joseph, Joe, Kaul, Stuti, Sorour, Youssef, Chvuka, Shingi, Mangos, Hilda, Neylon, Annette, Farrell, Katrina, Edwards, Hugh, Hanlon, Katharine, Fail, Tom, Goodrick, Margaret, Heartin, Earnest, Hoyle, Christine, Rye, Adam, Carr, Robert, Raj, Kavita, Krogh Jensen, Morten, Janmohamed, Riaz, Kaczmarski, Richard, Sugai, Taku, Ademokun, Debo, Chalmers, Isobel, Hodson, Andrew, Gomez, Cesar, Sadullah, Shala, Kwan, Mark, Longmuir, Karyn, Wilson-Morkeh, Isaac, Hunter, Ann, Martin, Murray, Saravanamuttu, Kandeepan, Sidra, Gamal, Burns, Sarah, Gibbs, Simon, Tholouli, Eleni, Aldouri, Maadh, Andrews, Vivienne, Eden, Ayed, Dungarwalla, Moez, White, Denise, Laird, Jane, Mitchell, Lindsey, Murphy, John, Paterson, Pamela, Raafat, Alaeddin, Mannari, Deepak, Davies, Simon, Austen, Belinda, Allford, Sarah, Kakalamudi, Sudhakar, Basu, Supratik, Hada, Sunil, Jacob, Abraham, MacWhonell, Alan, McCaig, Alison, Gelly, Keith, Kerr, Ron, Meiklejohn, David, Tauro, Sudhir, Lawes, Matthew, Bowen, Angela, Krishnamurthy, Suchitra, Byrne, Jenny, Dasgupta, Emma, Russell, Nigel, Stokley, Simone, Friis, Lone, Marcher, Claus, Bake, Bart, Chapple, Mary, Moreton, Paul, Omran, Asad, Patil, Kavita, Wright, David, Jack, Fergus, Maddams, Rebecca, Corser, Robert, Cranfield, Tanya, Dignum, Helen, Ganczakowski, Mary, Jones, Christopher, Craddock, Charles, Moss, Paula, Murray, Jim, Hemmaway, Claire, Craig, Joanne, Forsyth, Peter, Lush, Chris, Wei Bjerrum, Ole, Borregaard, Niels, Kampmann, Peter, Kjeldsen, Lars, Juul Nielsen, Ove, Niemann, Carsten, Lykke Petersen, Soeren, Udby Peter Møller, Lene, Alfred, Arun, Barker, Helen, Went, Richard, Groch, Henri, Mucklow, Stuart, Sampson, Rebecca, Chacko, Joseph, Hall, Rachel, Walewska, Renata, Creach, Desmond, Pottinger, Bryson, Addada, Juanah (Jo), Hamilton, Malcolm, Kerr, Paul, Ngu, Loretta, Rudin, Claudius, Ruell, Jackie, Dalley, Chris, Kaur, Harpreet, Reilly, John, Snowden, John, Ferguson, Paul, Dyer, Peter, Chandra, Deepak, DeVos, Johannes, Grey-Davies, Elisabeth, Hendry, Louise, Corbett, Timothy, Crowe, Josephine, Knechtli, Christopher, Wexler, Sarah, Fernandes, Savio, Neilson, Jeff, Houghton, John, Jowitt, Simon, Thomas-Dewing, Rowena, Williams, Mark, Zaman, Sonya, Cullis, Jonathan, Everington, Tamara, Grand, Effie, Hasan, Yasmin, Murrin, Richard, Wandoo, Farooq, Ismail, Saad, Mohite, Unmesh, Sati, Hamdi, Jenner, Matthew, Orchard, Kim, Richardson, Deborah, McCloskey, Kayleigh, Xu Chin, Kate, Fenella Willis, Neoh, Sud, Amit, Gharib, Maged, Nicholson, Toby, Bowen, David, Janes, Sarah, Eagleton, Helen, O'Hea, Anne-Marie, Pattinson, Jonathan, Hervey, Victoria, Lyons, Simon, Marshall, Scott, Nicolle, Annette, Vavyla, Maria, Burgess, Jordan, Somervaille, Tim, Somerfield, Sven, Mamat, Mohd, Tomlins, Jo, Salesh, Sana, David, Marianna, Maddox, Jamie, Plews, Diane, Dang, Ray, Potter, Mike, Ellis, Lauren, Nicholson, Emma, Keat, Sally, Ahmed Alhassani, Thubeena M., Anjum, Farahn, Chatterjee, Poulami, Stanchev, Atanas, Peters, Jayne, Lindsay-Holmes Srividhya, Sarah, Chodhouri, Senthil S., Eve, Heather, Smith, Steve, Roberts, Patrick, Rymes, Nicholas, Zhao New Oo, Rui, Ardeshna, Kirit, Blombery, Piers, Khwaja, Asim, Linch, David, Popat, Rakesh, Virchis, Andres, Yong, Kwee, McIntyre, Victoria, Horne, Gillian, Bokhari, Syed, Borg, Anton, Chapman, Oliver, Harrison, Beth, Jackson, Nicholas, Jobanputra, Shailesh, Narayanan, Mekkali, Rose, Peter, Oun, Hajer, Powell, Matthew, Gilles, Julie, Laing, Alison, Devanny, Ian, Horne, Gillian, Haskins, Lea, Micallef-Eynaud, Paul, Maclean, Peter, Alvares, Caroline, Kell, Jonathan, Knapper, Steve, Davidson, Kerri, McLintock, Lorna, Rogers, Stephen, Williamson, Peter, Corbett, Gillian, Goodman, Hugh, Islam, Shahid, Pullon, Humphrey, Johnson, Peter, Roddie, P.H., Maughan, Elizabeth, Mills, Juliet, Shafeek, Salim, Narat, Santosh, Aitchison, Robin, Pattinson, Jonathan, Bond, Lee, Munro, Laura and Edwards, David 2024. Fludarabine, cytarabine, granulocyte colony-stimulating factor, and idarubicin with gemtuzumab ozogamicin improves event-free survival in younger patients with newly diagnosed aml and overall survival in patients with npm1 and flt3 mutations. Journal of Clinical Oncology 42 (10) , pp. 1158-1168. 10.1200/JCO.23.00943
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Brunner, Andrew M., Esteve, Jordi, Porkka, Kimmo, Knapper, Steve ORCID: https://orcid.org/0000-0002-6405-4441, Traer, Elie, Scholl, Sebastian, Garcia-Manero, Guillermo, Vey, Norbert, Wermke, Martin, Janssen, Jeroen J. W. M., Narayan, Rupa, Fleming, Shaun, Loo, Sun, Tovar, Natalia, Kontro, Mika, Ottmann, Oliver G., Naidu, Purushotham, Sun, Haiying, Han, May, White, Roisin, Zhang, Na, Mohammed, Anisa, Sabatos?Peyton, Catherine A., Steensma, David P., Rinne, Mikael L., Borate, Uma M. and Wei, Andrew H. 2024. Phase Ib study of sabatolimab (MBG453), a novel immunotherapy targeting TIM?3 antibody, in combination with decitabine or azacitidine in high- or very high-risk myelodysplastic syndromes. American Journal of Hematology 99 (2) , E32-E36. 10.1002/ajh.27161
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Jimenez-Chillon, Carlos, Othman, Jad, Taussig, David, Jimenez-Vicente, Carlos, Martinez-Roca, Alexandra, Tiong, Ing Soo, Jain, Manish, Aries, James, Cakmak, Seda, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Kristensen, Daniel Tuyet, Murthy, Vidhya, Galani, Joy Zacharoula, Kallmeyer, Charlotte, Ngu, Loretta, Veale, David, Bolam, Simon, Orfali, Nina, Parker, Anne, Manson, Cara, Parker, Jane, Erblich, Thomas, Richardson, Deborah, Mokretar, Katya, Potter, Nicola, Overgaard, Ulrik Malthe, Roug, Anne Stidsholt, Wei, Andrew H., Esteve, Jordi, Jädersten, Martin, Russell, Nigel and Dillon, Richard 2024. Venetoclax-based low intensity therapy in molecular failure of NPM1 mutated AML. Blood Advances 8 (2) , pp. 343-352. 10.1182/bloodadvances.2023011106
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Fang, Zijian, Corbizi Fattori, Giuditta, McKerrell, Thomas, Boucher, Rebecca H., Jackson, Aimee, Fletcher, Rachel S., Forte, Dorian, Martin, Jose-Ezequiel, Fox, Sonia, Roberts, James, Glover, Rachel, Harris, Erica, Bridges, Hannah R., Grassi, Luigi, Rodriguez-Meira, Alba, Mead, Adam J., Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Ewing, Joanne, Butt, Nauman M., Jain, Manish, Francis, Sebastian, Clark, Fiona J., Coppell, Jason, McMullin, Mary F., Wadelin, Frances, Narayanan, Srinivasan, Milojkovic, Dragana, Drummond, Mark W., Sekhar, Mallika, ElDaly, Hesham, Hirst, Judy, Paramor, Maike, Baxter, E. Joanna, Godfrey, Anna L., Harrison, Claire N. and Méndez-Ferrer, Simón 2023. Tamoxifen for the treatment of myeloproliferative neoplasms: A Phase II clinical trial and exploratory analysis. Nature Communications 14 , 7725. 10.1038/s41467-023-43175-5
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Freeman, Sylvie D., Thomas, Abin ORCID: https://orcid.org/0000-0002-8283-6762, Thomas, Ian, Hills, Robert K., Vyas, Paresh, Gilkes, Amanda, Metzner, Marlen, Jakobsen, Niels Asger, Kennedy, Alison, Moore, Amy, Almuina, Nuria Marquez, Burns, Sarah, King, Sophie, Andrew, Georgia, Gallagher, Kathleen M.E., Sellar, Rob S., Cahalin, Paul, Weber, Duruta, Dennis, Mike, Mehta, Priyanka, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441 and Russell, Nigel H. 2023. Fractionated versus single dose Gemtuzumab Ozogamicin with determinants of benefit in older AML: UK NCRI AML18 Trial. Blood 142 (20) , pp. 1697-1707. 10.1182/blood.2023020630

Russell, Nigel, Cumming, Oliver, Othman, Jad, Dillon, Richard, Potter, Nicola, Wilhelm-Benartzi, Charlotte ORCID: https://orcid.org/0000-0003-4927-6158, Jovanovic, Jelena, Gilkes, Amanda, Batten, Leona, Canham, Joanna ORCID: https://orcid.org/0000-0003-3482-0990, Laura Hinson, Emily, Kottaridis, Panagiotis, Cavenagh, Jamie, Arnold, Claire, Dennis, Mike and Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441 2023. P484: Gemtuzumab-based induction chemotherapy combined with midostaurin for FLT3 mutated AML. Updated toxicity and interim survival analysis from the NCRI AML19v2 "Midotarg" Pilot Trial. HemaSphere 7 (S3) , e13145db. 10.1097/01.HS9.0000968844.13145.db
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Othman, Jad, Wilhelm-Benartzi, Charlotte S. ORCID: https://orcid.org/0000-0003-4927-6158, Dillon, Richard, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Freeman, Sylvie D., Batten, Leona M., Canham, Joanna ORCID: https://orcid.org/0000-0003-3482-0990, Hinson, Emily L., Wych, Julie, Betteridge, Sophie, Villiers, William, Kleeman, Michelle, Gilkes, Amanda Frances, Potter, Nicola, Overgaard, Ulrik, Mehta, Priyanka, Kottaridis, Panagiotis, Cavenagh, Jamie, Hemmaway, Claire Jane, Arnold, Claire, Dennis, Mike and Russell, Nigel H. 2023. A randomised comparison of CPX-351 and FLAG-Ida in adverse karyotype AML and high-risk MDS: the UK NCRI AML19 trial. Blood Advances 7 (16) , pp. 4539-4549. 10.1182/bloodadvances.2023010276
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Othman, Jad, Potter, Nicola, Mokretar, Katya, Taussig, David, Khan, Anjum, Krishnamurthy, Pramila, Latif, Anne-Louise, Cahalin, Paul, Aries, James, Amer, Mariam, Belsham, Edward, Conneally, Eibhlin, Craddock, Charles, Culligan, Dominic, Dennis, Mike, Duncan, Caroline, Freeman, Sylvie D., Furness, Caroline, Gilkes, Amanda, Gkreka, Paraskevi, Hodgson, Katherine, Ingram, Wendy, Jain, Manish, King, Andrew, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Kottaridis, Panagiotis, McMullin, Mary Frances, Mohite, Unmesh, Ngu, Loretta, O’Nions, Jenny, Patrick, Katharine, Rider, Tom, Roberts, Wing, Severinsen, Marianne Tang, Storrar, Neill, Taylor, Tom, Russell, Nigel H. and Dillon, Richard 2023. FLT3 inhibitors as MRD-guided salvage treatment for molecular failure in FLT3 mutated AML. Leukemia 37 (10) , pp. 2066-2072. 10.1038/s41375-023-01994-x
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Harrison, Claire N., Nangalia, Jyoti, Boucher, Rebecca, Jackson, Aimee, Yap, Christina, O'Sullivan, Jennifer, Fox, Sonia, Ailts, Isaak, Dueck, Amylou C., Geyer, Holly L., Mesa, Ruben A., Dunn, William G., Nadezhdin, Eugene, Curto-Garcia, Natalia, Green, Anna, Wilkins, Bridget, Coppell, Jason, Laurie, John, Garg, Mamta, Ewing, Joanne, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Crowe, Josephine, Chen, Frederick, Koutsavlis, Ioannis, Godfrey, Anna, Arami, Siamak, Drummond, Mark, Byrne, Jennifer, Clark, Fiona, Mead-Harvey, Carolyn, Baxter, Elizabeth Joanna, McMullin, Mary Frances and Mead, Adam J. 2023. Ruxolitinib versus best available therapy for polycythemia vera intolerant or resistant to hydroxycarbamide in a randomized trial. Journal of Clinical Oncology 41 (19) , pp. 3534-3544. 10.1200/JCO.22.01935
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Iland, Harry J., Russell, Nigel H., Dillon, Richard, Schuh, Andre C., Tedjaseputra, Aditya, Wei, Andrew H., Khwaja, Asim, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Lane, Steven W., Reynolds, John, McMullin, Mary Frances Frances, Martin, Annalise Maria, Tan, Peter, Taussig, David Christopher C., Wong, Anny, Taper, John M., Fraga, Christina, Kelly, Richard, Tawana, Kiran, Mehta, Priyanka, Mina, Alain, Altman, Jessica K., Mølle, Ingolf, Tauro, Sudhir and Tholouli, Eleni 2023. Characteristics and outcomes of patients with acute promyelocytic leukemia and extreme hyperleukocytosis at presentation. Blood Advances 7 (11) , pp. 2580-2585. 10.1182/bloodadvances.2022007126
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Mussai, Francis, De Santo, Carmela, Cheng, Paul, Thomas, Ian F., Ariti, Cono ORCID: https://orcid.org/0000-0001-7615-0935, Upton, Laura, Scarpa, Ugo, Stavrou, Victoria, Sydenham, Mia, Burnett, Alan K., Knapper, Steven K. ORCID: https://orcid.org/0000-0002-6405-4441, Mehta, Priyanka, McMullin, Mary F., Copland, Mhairi, Russell, Nigel H. and Dennis, Mike 2023. A randomised evaluation of low‐dose Ara‐ C plus pegylated recombinant arginase BCT ‐100 versus low dose Ara‐ C in older unfit patients with acute myeloid leukaemia: Results from the LI ‐1 trial. British Journal of Haematology 200 (5) , pp. 573-578. 10.1111/bjh.18560
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Rastogi, Namrata, Gonzalez, Juan Bautista Menendez, Srivastava, Vikas, Alanazi, Bader, Alanazi, Rehab N., Hughes, Owen M., O'Neill, Niamh S., Gilkes, Amanda, Ashley, Neil, Deshpande, Sumukh, Andrews, Robert, Mead, Adam, Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Darley, Richard ORCID: https://orcid.org/0000-0003-0879-0724 and Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 2023. Nuclear factor I-C overexpression promotes monocytic development and cell survival in acute myeloid leukemia. Leukemia 37 , pp. 276-287. 10.1038/s41375-022-01801-z
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Mehta, Priyanka, Telford, Nick, Wragg, Chris, Dillon, Richard, Freeman, Sylvie, Finnegan, Damian, Hamblin, Angela, Copland, Mhairi and Knapper, Steve ORCID: https://orcid.org/0000-0002-6405-4441 2023. Recommendations for laboratory testing of UK patients with acute myeloid leukaemia. British Journal of Haematology 200 (2) , pp. 150-159. 10.1111/bjh.18516

Russell, Nigel H., Wilhelm-Benartzi, Charlotte ORCID: https://orcid.org/0000-0003-4927-6158, Knapper, Steve ORCID: https://orcid.org/0000-0002-6405-4441, Batten, Leona M., Canham, Joanna ORCID: https://orcid.org/0000-0003-3482-0990, Hinson, Emily L., Overgaard, Ulrik Malthe, Gilkes, Amanda, Othman, Jad, Potter, Nicola, Dillon, Richard, Mehta, Priyanka, Kottaridis, Panagiotis, Cavenagh, Jamie, Hemmaway, Claire, Arnold, Claire, Freeman, Sylvie D and Dennis, Mike 2022. FLAG-Ida combined with Gemtuzumab Ozogamicin (GO) improves event free survival in younger patients with newly diagnosed Acute Myeloid Leukaemia (AML) and shows an overall survival benefit in NPM1 and FLT3 mutated subgroups. Results from the UK NCRI AML19 trial. Blood 140 (S1) , pp. 526-528. 10.1182/blood-2022-162377

Wood, Henry, Bourlon, Christianne, Kulasekararaj, Austin, Borg, Albert, Pavlu, Jiri, Elder, Patrick, Taussig, David C, Veitch, Scott, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Othman, Jad, Dillon, Richard, Aries, James, Mitchell, Emily, Basheer, Faisal, Leak, Steven, Murthy, Vidhya, Cross, Joe W, Mehta, Priyanka, Jain, Manish, Khan, Anjum, Lam, Ho, Leong, Sarah, O'Nions, Jenny, Craddock, Charles, Potter, Victoria, Copland, Mhairi and Krishnamurthy, Pramila 2022. Venetoclax-based non-intensive combinations successfully salvage molecular relapse of acute myeloid leukemia and are an important bridge to cellular therapy in relapsed/refractory disease - real-world data from a UK-wide programme. Blood 140 (S1) , pp. 9016-9018. 10.1182/blood-2022-167097

Freeman, Sylvie D, Thomas, Abin, Thomas, Ian, Vyas, Paresh, Gilkes, Amanda, Metzner, Marlen, Jakobsen, Niels Asger, Kennedy, Alison, Moore, Amy, Marquez Almuina, Nuria, Burns, Sarah, King, Sophie, Andrew, Georgia M., Gallagher, Kathleen M.E., Sellar, Rob, Cahalin, Paul, Weber, Duruta, Dennis, Mike, Mehta, Priyanka, Knapper, Steve ORCID: https://orcid.org/0000-0002-6405-4441 and Russell, Nigel H. 2022. A randomized comparison of the fractionated versus single dose schedule of Gemtuzumab Ozogamicin at induction with determinants of benefit for older AML patients: UK NCRI AML18 trial results. Blood 140 (S1) , pp. 532-533. 10.1182/blood-2022-162245

Othman, Jad, Dillon, Richard, Wilhelm-Benartzi, Charlotte ORCID: https://orcid.org/0000-0003-4927-6158, Knapper, Steve ORCID: https://orcid.org/0000-0002-6405-4441, Batten, Leona M, Canham, Joanna ORCID: https://orcid.org/0000-0003-3482-0990, Hinson, Emily L., Villiers, William, Kleeman, Michelle, Gilkes, Amanda, Potter, Nicola, Overgaard, Ulrik Malthe, Mehta, Priyanka, Kottaridis, Panos, Cavenagh, Jamie, Hemmaway, Claire, Arnold, Claire, Dennis, Mike and Russell, Nigel H. 2022. Genomic correlates of outcome in a randomised comparison of CPX-351 and FLAG-Ida in high-risk acute myeloid leukaemia and myelodysplastic syndrome: results from the UK NCRI AML19 Trial. Presented at: 64th ASH Annual Meeting and Exposition, New Orleans, Louisiana, 10-13 December 2022. Blood. , vol.140 (S1) American Society of Hematology, pp. 1036-1038. 10.1182/blood-2022-159433

Dillon, Richard, Maycock, Shanna, Jackson, Aimee, Fox, Sonia, Freeman, Sylvie, Craddock, Charles, Thomas, Catherine, Homer, Emma, Leahy, Jane, Mamwell, Anna, Potter, Nicola, Russell, Nigel, Wei, Andrew, Ommen, Hans Beier, Hemmaway, Claire, Knapper, Steve ORCID: https://orcid.org/0000-0002-6405-4441 and Billingham, Lucinda 2022. Venetoclax combined with low dose cytarabine compared to standard of care intensive chemotherapy for the treatment of favourable risk adult acute myeloid leukaemia (VICTOR): Study protocol for an international, open-label, multicentre, molecularly-guided randomised, phase II trial. BMC Cancer 22 , 1174. 10.1186/s12885-022-10221-2
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Nicholson, Rachael, Menezes, Ana C., Azevedo, Aleksandra, Leckenby, Adam, Davies, Sara, Seedhouse, Claire, Gilkes, Amanda, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 and Darley, Richard L. ORCID: https://orcid.org/0000-0003-0879-0724 2022. Protein kinase C epsilon overexpression is associated with poor patient outcomes in AML and promotes daunorubicin resistance through p-glycoprotein-mediated drug efflux. Frontiers in Oncology 12 , 840046. 10.3389/fonc.2022.840046
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Coats, Thomas, Bean, Daniel, Basset, Aymeric, Sirkis, Tamir, Brammeld, Jonathan, Johnson, Sean, Thomas, Ian, Gilkes, Amanda, Raj, Kavita, Dennis, Mike, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Mehta, Priyanka, Khwaja, Asim, Hunter, Hannah, Tauro, Sudhir, Bowen, David, Jones, Gail, Dobson, Richard, Russell, Nigel and Dillon, Richard 2022. A novel algorithmic approach to generate consensus treatment guidelines in adult acute myeloid leukaemia. British Journal of Haematology 196 (6) , pp. 1337-1343. 10.1111/bjh.18013
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Dennis, Mike, Thomas, Ian F., Ariti, Cono ORCID: https://orcid.org/0000-0001-7615-0935, Upton, Laura, Burnett, Alan K., Gilkes, Amanda, Radia, Rohini, Hemmaway, Claire, Mehta, Priyanka, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Clark, Richard E., Copland, Mhairi, Russell, Nigel and Hills, Robert K. 2021. Randomized evaluation of quizartinib and low-dose ara-C vs low-dose ara-C in older acute myeloid leukemia patients. Blood Advances 5 (24) , pp. 5621-5625. 10.1182/bloodadvances.2021005038
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Salisbury, Richard A., Curto-Garcia, Natalia, O'Sullivan, Jennifer, Chen, Frederick, Polzella, Paolo, Godfrey, Anna L., Russell, James, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Willan, John, Frewin, Rebecca, Joshi, Shivani, Arami, Siamak, Burns, Sarah, Teh, Chun Huat, Wadelin, Frances, Dhanapal, Jaymathi, Neelakantan, Pratap, Milojkovic, Dragana, Psaila, Beth, Szydlo, Richard, Francis, Sebastian, Cargo, Catherine, Jain, Manish, McGregor, Andrew, Wallis, Louise, Duncombe, Andrew, Hussein, Hayder, Dyer, Peter, Munro, Laura, Bond, Lee, McMullin, Mary Frances, Somervaille, Tim C. P., Garg, Mamta, Sekhar, Mallika, Harrison, Claire, Mead, Adam J. and Innes, Andrew J. 2021. Results of a national UK physician reported survey of COVID-19 infection in patients with a myeloproliferative neoplasm. Leukemia 35 , pp. 2424-2430. 10.1038/s41375-021-01143-2
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Rastogi, Namrata, Baker, Sarah ORCID: https://orcid.org/0000-0002-7474-9757, Man, Stephen ORCID: https://orcid.org/0000-0001-9103-1686, Uger, Robert A., Wong, Mark, Coles, Steve J., Hodges, Marie, Gilkes, Amanda, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Darley, Richard ORCID: https://orcid.org/0000-0003-0879-0724 and Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 2021. Use of an anti-CD200 blocking antibody improves immune responses to AML in vitro and in vivo. British Journal of Haematology 193 (1) , pp. 155-159. 10.1111/bjh.17125
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Burnett, Alan K., Russell, Nigel H., Hills, Robert K., Knapper, Stephen ORCID: https://orcid.org/0000-0002-6405-4441, Freeman, Sylvie, Huntly, Brian, Clark, Richard E., Thomas, Ian F., Kjeldsen, Lars, McMullin, Mary Frances, Drummond, Mark, Kell, Jonathan and Spearing, Ruth 2021. Defining the optimal total number of chemotherapy courses in younger patients with acute myeloid leukemia: a comparison of three versus four courses. Journal of Clinical Oncology 39 (8) , pp. 890-901. 10.1200/JCO.20.01170
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Montesinos, Pau, Roboz, Gail J., Bulabois, Claude-Eric, Subklewe, Marion, Platzbecker, Uwe, Ofran, Yishai, Papayannidis, Cristina, Wierzbowska, Agnieszka, Shin, Ho Jin, Doronin, Vadim, Deneberg, Stefan, Yeh, Su-Peng, Ozcan, Mehmet Ali, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Cortes, Jorge, Pollyea, Daniel A., Ossenkoppele, Gert, Giralt, Sergio, Döhner, Hartmut, Heuser, Michael, Xiu, Liang, Singh, Indrajeet, Huang, Fei, Larsen, Julie S. and Wei, Andrew H. 2021. Safety and efficacy of talacotuzumab plus decitabine or decitabine alone in patients with acute myeloid leukemia not eligible for chemotherapy: results from a multicenter, randomized, phase 2/3 study. Leukemia 35 (1) , 62–74. 10.1038/s41375-020-0773-5
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Peterlin, Pierre, Chevallier, Patrice, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441 and Collin, Matthew 2021. FLT3 ligand in acute myeloid leukemia: a simple test with deep implications. Leukemia & Lymphoma 62 (2) , pp. 264-270. 10.1080/10428194.2020.1834091
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Zabkiewicz, Joanna ORCID: https://orcid.org/0000-0003-0951-3825, Lazenby, Michelle, Edwards, Gareth, Bygrave, Ceri A., Omidvar, Nader, Zhuang, Lihui, Knapper, Steve ORCID: https://orcid.org/0000-0002-6405-4441, Guy, Carol, Hills, Robert K. ORCID: https://orcid.org/0000-0003-0166-0062, Burnett, Alan K. and Alvares, Caroline L. ORCID: https://orcid.org/0000-0003-4391-9802 2020. Combination of a mitogen‐activated protein kinase inhibitor with the tyrosine kinase inhibitor pacritinib combats cell adhesion‐based residual disease and prevents re‐expansion of FLT3 ‐ITD acute myeloid leukaemia. British Journal of Haematology 191 (2) , pp. 231-242. 10.1111/bjh.16665
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Hogan, Francesca L., Williams, Victoria and Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441 2020. FLT3 Inhibition in acute myeloid leukaemia - current knowledge and future prospects. Current Cancer Drug Targets 20 (7) , pp. 513-531. 10.2174/1570163817666200518075820
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Alanazi, Bader, Munje, Chinmay R., Rastogi, Namrata, Williamson, Andrew J. K., Taylor, Samuel, Hole, Paul S., Hodges, Marie, Doyle, Michelle, Baker, Sarah ORCID: https://orcid.org/0000-0002-7474-9757, Gilkes, Amanda F., Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Pierce, Andrew, Whetton, Anthony D., Darley, Richard L. ORCID: https://orcid.org/0000-0003-0879-0724 and Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 2020. Integrated nuclear proteomics and transcriptomics identifies S100A4 as a therapeutic target in acute myeloid leukemia. Leukemia 34 (2) , pp. 427-440. 10.1038/s41375-019-0596-4
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Milne, Paul, Wilhelm-Benartzi, Charlotte ORCID: https://orcid.org/0000-0003-4927-6158, Grunwald, Michael R., Bigley, Venetia, Dillon, Richard, Freeman, Sylvie D., Gallagher, Kathleen, Publicover, Amy, Pagan, Sarah, Marr, Helen, Jones, Gail L., Dickinson, Anne M., Grech, Angela, Burnett, Alan K., Russell, Nigel H., Levis, Mark, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441 and Collin, Matthew 2019. Serum Flt3 ligand is a biomarker of progenitor cell mass and prognosis in acute myeloid leukemia. Blood Advances 3 (20) , pp. 3052-3061. 10.1182/bloodadvances.2019000197
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Legge, Sophie E., Pardinas, Antonio F. ORCID: https://orcid.org/0000-0001-6845-7590, Helthuis, Marinka, Jansen, John A., Jollie, Karel, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, MacCabe, James H., Rujescu, Dan, Collier, David A., O'Donovan, Michael C. ORCID: https://orcid.org/0000-0001-7073-2379, Owen, Michael J. ORCID: https://orcid.org/0000-0003-4798-0862 and Walters, James T. R. ORCID: https://orcid.org/0000-0002-6980-4053 2019. A genome-wide association study in individuals of African ancestry reveals the importance of the Duffy-null genotype in the assessment of clozapine-related neutropenia. Molecular Psychiatry 24 , pp. 328-337. 10.1038/s41380-018-0335-7
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McMullin, M. F., Harrison, C. N., Ali, S., Cargo, C., Chen, F., Ewing, J, Garg, M., Godfrey, A., Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, McLorcan, D., Nangalia, J., Sekhar, M., Wadelin, F. and Mead, A. J. 2019. A guideline for the diagnosis and management of polycythaemia vera. British Journal of Haematology 184 (2) , pp. 176-191. 10.1111/bjh.15648
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Burnett, Alan K, Das Gupta, Emma, Knapper, Steve ORCID: https://orcid.org/0000-0002-6405-4441, Khwaja, Asim, Sweeney, Marion ORCID: https://orcid.org/0000-0003-0713-0855, Kjeldsen, Lars, Hawkins, Timothy, Betteridge, Sophie E., Cahalin, Paul, Clark, Richard E., Hills, Robert K. ORCID: https://orcid.org/0000-0003-0166-0062 and Russell, Nigel H. 2018. Addition of the mammalian target of rapamycin inhibitor, Everolimus, to consolidation therapy in acute myeloid leukaemia: experience from the UK NCRI AML17 trial. Haematologica 103 (10) , pp. 1654-1661. 10.3324/haematol.2018.189514
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Harrison, Claire N., Mead, Adam J., Panchal, Anesh, Fox, Sonia, Yap, Christina, Gbandi, Emmanouela, Houlton, Aimee, Alimam, Samah, Ewing, Joanne, Wood, Marion, Chen, Frederick, Coppell, Jason, Panoskaltsis, Nicki, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Ali, Sahra, Hamblin, Angela, Scherber, Robyn, Dueck, Amylou C., Cross, Nicholas C. P., Mesa, Ruben and McMullin, Mary Frances 2017. Ruxolitinib vs best available therapy for ET intolerant or resistant to hydroxycarbamide. Blood 130 (17) , pp. 1889-1897. 10.1182/blood-2017-05-785790
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Williams, Jenna, Heppel, Nicole, Britt-Compton, Bethan, Grimstead, Julia, Robinson, Rhiannon, Tauro, Sudhir, Bowen, David, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Groves, Michael, Hills, Robert ORCID: https://orcid.org/0000-0003-0166-0062, Pepper, Christopher J., Baird, Duncan M. ORCID: https://orcid.org/0000-0001-8408-5467 and Fegan, Christopher D. ORCID: https://orcid.org/0000-0001-9685-0621 2017. Telomere length is an independent prognostic marker in MDS but not in de novo AML. British Journal of Haematology 178 (2) , pp. 240-249.
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Khan, N., Hills, R. K. ORCID: https://orcid.org/0000-0003-0166-0062, Virgo, P., Couzens, S., Clark, N., Gilkes, A., Richardson, P., Knapper, S. ORCID: https://orcid.org/0000-0002-6405-4441, Grimwade, D., Russell, N. H., Burnett, A. K. and Freeman, S. D. 2017. Expression of CD33 is a predictive factor for effect of gemtuzumab ozogamicin at different doses in adult acute myeloid leukaemia. Leukemia 31 , pp. 1059-1068. 10.1038/leu.2016.309
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Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Russell, Nigel, Gilkes, Amanda, Hills, Robert K. ORCID: https://orcid.org/0000-0003-0166-0062, Gale, Rosemary E., Cavenagh, James D., Jones, Gail, Kjeldsen, Lars, Grunwald, Michael R., Thomas, Ian, Konig, Heiko, Levis, Mark J. and Burnett, Alan K. 2017. A randomized assessment of adding the kinase inhibitor lestaurtinib to first-line chemotherapy for FLT3-mutated AML. Blood 129 (9) , pp. 1143-1154. 10.1182/blood-2016-07-730648
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Butt, Nauman M., Lambert, Jonathan, Ali, Sahra, Beer, Philip A., Cross, Nicholas C. P., Duncombe, Andrew, Ewing, Joanne, Harrison, Claire N., Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, McLornan, Donal, Mead, Adam J., Radia, Deepti and Bain, Barbara J. 2017. Guideline for the investigation and management of eosinophilia. British Journal of Haematology 176 (4) , pp. 553-572. 10.1111/bjh.14488
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Khan, Naeem, Hills, Robert ORCID: https://orcid.org/0000-0003-0166-0062, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Steadman, Lora, Qureshi, Ushna, Rector, Jerrold L., Bradbury, Charlotte, Russell, Nigel H., Vyas, Paresh, Burnett, Alan K., Grimwade, David, Hole, Paul and Freeman, Sylvie D. 2016. Normal hematopoietic progenitor subsets have distinct reactive oxygen species, BCl2 and cell-cycle profiles that are decoupled from maturation in acute myeloid leukemia. PLOS ONE 11 (9) , e0163291. 10.1371/journal.pone.0163291
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Beauverd, Yan, Radia, Deepti, Cargo, Catherine, Knapper, Steve ORCID: https://orcid.org/0000-0002-6405-4441, Drummond, Mark, Pillai, Arvind, Harrison, Claire and Robinson, Susan 2016. Pegylated interferon alpha-2a for essential thrombocythemia during pregnancy: outcome and safety. A case series. Haematologica 101 (5) , e182-e184. 10.3324/haematol.2015.139691
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Zabkiewicz, Joanna ORCID: https://orcid.org/0000-0003-0951-3825, Gilmour, Marie, Hills, Robert ORCID: https://orcid.org/0000-0003-0166-0062, Vyas, Pares, Bone, Elizabeth, Davidson, Alan, Burnett, Alan and Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441 2016. The targeted histone deacetylase inhibitor tefinostat (CHR-2845) shows selective in vitro efficacy in monocytoid-lineage leukaemias. Oncotarget 7 (13) , pp. 16650-16662. 10.18632/oncotarget.7692
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Burnett, Alan K., Russell, Nigel H., Hills, Robert K. ORCID: https://orcid.org/0000-0003-0166-0062, Bowen, David, Kell, Jonathan, Knapper, Steve ORCID: https://orcid.org/0000-0002-6405-4441, Morgan, Yvonne G., Lok, Jennie, Grech, Angela, Jones, Gail, Khwaja, Asim, Friis, Lone, McMullin, Mary Frances, Hunter, Ann, Clark, Richard E. and Grimwade, David 2015. Arsenic trioxide and all-trans retinoic acid treatment for acute promyelocytic leukaemia in all risk groups (AML17): results of a randomised, controlled, phase 3 trial. Lancet Oncology 16 (13) , pp. 1295-1305. 10.1016/S1470-2045(15)00193-X

Coles, S. J., Gilmour, M. N., Reid, R., Knapper, S. ORCID: https://orcid.org/0000-0002-6405-4441, Burnett, A. K., Man, S. ORCID: https://orcid.org/0000-0001-9103-1686, Tonks, A. ORCID: https://orcid.org/0000-0002-6073-4976 and Darley, R. L. ORCID: https://orcid.org/0000-0003-0879-0724 2015. The immunosuppressive ligands PD-L1 and CD200 are linked in AML T-cell immunosuppression: identification of a new immunotherapeutic synapse. Leukemia 29 , pp. 1952-1954. 10.1038/leu.2015.62

Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441 2015. The FLAM regimen: revisiting time sequential induction therapy for patients with poor-risk acute myeloid leukemia. Haematologica 100 (9) , pp. 1105-1107. 10.3324/haematol.2015.134023

Mead, Adam J., Milojkovic, Dragana, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Garg, Mamta, Chacko, Joseph, Farquharson, Mira, Yin, John, Ali, Sahra, Clark, Richard E., Andrews, Chris, Dawson, Meryem Ktiouet and Harrison, Claire 2015. Response to ruxolitinib in patients with intermediate-1-, intermediate-2-, and high-risk myelofibrosis: results of the UK ROBUST Trial. British Journal of Haematology 170 (1) , pp. 29-39. 10.1111/bjh.13379

Reilly, John T., McMullin, Mary Frances, Beer, Philip A., Butt, Nauman, Conneally, Eibhlin, Duncombe, Andrew S., Green, Anthony R., Mikhaeel, George, Gilleece, Marie H., Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Mead, Adam J., Mesa, Ruben A., Sekhar, Mallika and Harrison, Claire N. 2014. Use of JAK inhibitors in the management of myelofibrosis: a revision of the British Committee for Standards in Haematology Guidelines for Investigation and Management of Myelofibrosis 2012. British Journal of Haematology 167 (3) , pp. 418-420. 10.1111/bjh.12985
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Andersen, Christen Lykkegaard, Bjørn, Mads Emil, McMullin, Mary Frances, Harrison, Claire, Samuelsson, Jan, Ejerblad, Elisabeth, Zweegman, Sonja, Fernandes, Savio, Bareford, David, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Löfvenberg, Eva, Linder, Olle, Andreasson, Bjørn, Ahlstrand, Erik, Jensen, Morten Krogh, Bjerrum, Ole Weis, Vestergaard, Hanne, Larsen, Herdis, Klausen, Tobias Wirenfeldt, Mourits-Andersen, Torben, Skov, Vibe, Thomassen, Mads, Kruse, Torben, Grønbæk, Kirsten and Hasselbalch, Hans Carl 2014. Circulating YKL-40 in patients with essential thrombocythemia and polycythemia vera treated with the novel histone deacetylase inhibitor vorinostat. Leukemia Research 38 (7) , pp. 816-821. 10.1016/j.leukres.2014.04.002

Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Chevassut, Timothy, Duarte, Rafael, Bergua, Juan Miguel, Salamero, Olga, Johansen, Malin, Jacobsen, Tove Flem, Hals, Petter-Arnt, Rasch, Wenche, Gianella-Borradori, Athos and Smith, Matthew 2014. Elacytarabine in relapsed/refractory acute myeloid leukaemia: an evaluation of clinical efficacy, pharmacokinetics, cardiac safety and effects on lipid profile. Leukemia Research 38 (3) , pp. 346-351. 10.1016/j.leukres.2013.12.011

Burnett, Alan Kenneth, Russell, N. H., Hunter, A. E., Milligan, D., Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Wheatley, K., Yin, J., McMullin, M. F., Ali, S., Bowen, D. and Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062 2013. Clofarabine doubles the response rate in older patients with acute myeloid leukemia but does not improve survival. Blood 122 (8) , pp. 1384-1394. 10.1182/blood-2013-04-496596

Moore, A. S., Kearns, P. R., Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Pearson, A. D. J. and Zwaan, C. M. 2013. Novel therapies for children with acute myeloid leukaemia. Leukemia 27 (7) , pp. 1451-1460. 10.1038/leu.2013.106

Andersen, Christen L., McMullin, Mary F., Ejerblad, Elisabeth, Zweegman, Sonja, Harrison, Claire, Fernandes, Savio, Bareford, David, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Samuelsson, Jan, Löfvenberg, Eva, Linder, Olle, Andreasson, Bjørn, Ahlstrand, Erik, Jensen, Morten K., Bjerrum, Ole W., Vestergaard, Hanne, Larsen, Herdis, Klausen, Tobias W., Mourits-Andersen, Torben and Hasselbalch, Hans C. 2013. A phase II study of vorinostat (MK-0683) in patients with polycythaemia vera and essential thrombocythaemia. British Journal of Haematology 162 (4) , pp. 498-508. 10.1111/bjh.12416

Craddock, C., Quek, L., Goardon, N., Freeman, S., Siddique, S., Raghavan, M., Aztberger, A., Schuh, A., Grimwade, D., Ivey, A., Virgo, P., Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062, McSkeane, T., Arrazi, J., Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Brookes, C., Davies, B., Price, A., Wall, K., Griffiths, M., Cavenagh, J., Majeti, R., Weissman, I., Burnett, Alan Kenneth and Vyas, P. 2013. Azacitidine fails to eradicate leukemic stem/progenitor cell populations in patients with acute myeloid leukemia and myelodysplasia. Leukemia 27 (5) , pp. 1028-1036. 10.1038/leu.2012.312

Walsby, Elisabeth Jane ORCID: https://orcid.org/0000-0001-8523-5017, Lazenby, Michelle, Pepper, Christopher John, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441 and Burnett, Alan Kenneth 2013. The HSP90 inhibitor NVP-AUY922-AG inhibits the PI3K and IKK signalling pathways and synergizes with cytarabine in acute myeloid leukaemia cells. British Journal of Haematology 161 (1) , pp. 57-67. 10.1111/bjh.12215

Reilly, John T., McMullin, Mary Frances, Beer, Philip A., Butt, Nauman, Conneally, Eibhlean, Duncombe, Andrew, Green, Anthony R., Michaeel, N. George, Gilleece, Marie H., Hall, Georgina W., Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Mead, Adam, Mesa, Ruben A., Sekhar, Mallika, Wilkins, Bridget and Harrison, Claire N. 2012. Guideline for the diagnosis and management of myelofibrosis. British Journal of Haematology 158 (4) , pp. 453-471. 10.1111/j.1365-2141.2012.09179.x

Taylor, Philip Russel ORCID: https://orcid.org/0000-0003-0163-1421, Heydeck, Dagmar, Jones, Gareth Wyn, Kronke, Gerhard, Funk, Colin D., Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Adams, Deborah, Kuhn, Hartmut and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2012. Development of myeloproliferative disease in 12/15-lipoxygenase deficiency [Letter]. Blood 119 (25) , pp. 6173-6174. 10.1182/blood-2012-02-410928

Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, White, Paul Charles ORCID: https://orcid.org/0000-0002-6562-4696, Levis, Mark J., Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062, Russell, Nigel H. and Burnett, Alan Kenneth 2011. The efficacy of the FLT3 inhibitor Lestaurtinib in AML depends on adequate plasma inhibitory activity (PIA), and is unaffected by rising FLT ligand levels: an update of the NCRI AML15 & 17 trials. Blood -New York- 118 (21) , p. 194.

Szegezdi, Eva, Reis, Carlos R., Sloot, Almer M. van der, Natoni, Alessandro, O'Reilly, Aoife, Reeve, Janice, Cool, Robbert H., O'Dwyer, Michael, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Serrano, Luis, Quax, Wim J. and Samali, Afshin 2011. Targeting AML through DR4 with a novel variant of rhTRAIL. Journal of Cellular and Molecular Medicine 15 (10) , pp. 2216-2231. 10.1111/j.1582-4934.2010.01211.x
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Sato, Takashi, Yang, Xiaochuan, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, White, Paul Charles ORCID: https://orcid.org/0000-0002-6562-4696, Smith, B. Douglas, Galkin, Steven, Small, Donald, Burnett, Alan Kenneth and Levis, Mark 2011. FLT3 ligand impedes the efficacy of FLT3 inhibitors in vitro and in vivo. Blood 117 (12) , pp. 3286-3293. 10.1182/blood-2010-01-266742

Walsby, Elisabeth Jane ORCID: https://orcid.org/0000-0001-8523-5017, Coles, Steven, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441 and Burnett, Alan Kenneth 2011. The topoisomerase II inhibitor voreloxin causes cell cycle arrest and apoptosis in myeloid leukemia cells and acts in synergy with cytarabine. Haematologica 96 (3) , pp. 393-399. 10.3324/haematol.2010.032680

Goardon, Nicolas, Marchi, Emanuele, Atzberger, Ann, Quek, Lynn, Schuh, Anna, Soneji, Shamit, Woll, Petter, Mead, Adam, Alford, Kate A., Rout, Raj, Chaudhury, Salma, Gilkes, Amanda F., Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Beldjord, Kheira, Begum, Suriya, Rose, Susan, Geddes, Nicola, Griffiths, Mike, Standen, Graham, Sternberg, Alexander, Cavenagh, Jamie, Hunter, Hannah, Bowen, David, Killick, Sally, Robinson, Lisa, Price, Andrew, Macintyre, Elizabeth, Virgo, Paul, Burnett, Alan Kenneth, Craddock, Charles, Enver, Tariq, Jacobsen, Sten Eirik W., Porcher, Catherine and Vyas, Paresh 2011. Coexistence Of LMPP-like and GMP-like leukemia stem cells in acute myeloid leukemia. Cancer Cell 19 (1) , pp. 138-152. 10.1016/j.ccr.2010.12.012

Dijk, Marianne van, Murphy, Eoin, Morrell, Ruth, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, O'Dwyer, Michael, Samali, Afshin and Szegezdi, Eva 2011. The proteasome inhibitor bortezomib sensitizes AML with myelomonocytic differentiation to TRAIL mediated apoptosis. Cancers 3 (4) , pp. 1329-1350. 10.3390/cancers3011329
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Moore, Catherine, Galiano, Monica, Lackenby, Angie, Abdelrahman, Tamer, Barnes, Rosemary Ann, Evans, Meirion Rhys ORCID: https://orcid.org/0000-0003-3578-1866, Fegan, Christopher, Froude, Susannah, Hastings, Mark, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Litt, Emma, Price, Nicola, Salmon, Roland, Temple, Mark and Davies, Eleri 2011. Evidence of person-to-person transmission of oseltamivir-resistant pandemic influenza A(H1N1) 2009 virus in a hematology unit. International Journal of Infectious Diseases 203 (1) , pp. 18-24. 10.1093/infdis/jiq007

Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441 2011. The clinical development of FLT3 inhibitors in acute myeloid leukemia. Expert Opinion on Investigational Drugs 20 (10) , pp. 1377-1395. 10.1517/13543784.2011.611802

Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Burnett, Alan Kenneth, Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062, Small, Donald and Levis, Mark 2009. Lestaurtinib FLT3 inhibitory activity is modulated by concomitant azole therapy and may Influence relapse risk. Blood -New York- 114 (22) , p. 326.

Burnett, Alan Kenneth and Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441 2009. Acute myeloid leukaemia. Treleaven, Jennifer G. and Barrett, A. John, eds. Hematopoietic Stem Cell Transplantation in Clinical Practice, Edinburgh: Churchill Livingstone Elsevier, pp. 25-34.

Hewamana, Saman, Pepper, Christopher John, Couzens, Stephen, Thomas, Alun and Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441 2008. IgM multiple myeloma: a diagnostic challenge in a patient with coexisting chronic lymphocytic leukaemia. International Journal of Hematology 88 (4) , pp. 424-427. 10.1007/s12185-008-0179-z

Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441 2007. FLT3 inhibition in acute myeloid leukaemia. British Journal of Haematology 138 (6) , pp. 687-699. 10.1111/j.1365-2141.2007.06700.x
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Burnett, Alan Kenneth and Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441 2007. Targeting treatment in AML. Hematology: American Society of Haematology Education Program Book 2007 (1) , pp. 429-434. 10.1182/asheducation-2007.1.429

Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Burnett, Alan K., Littlewood, Tim, Kell, William Jonathan, Agrawal, Sam, Chopra, Raj, Clark, Richard, Levis, Mark J. and Small, Donald 2006. A phase 2 trial of the FLT3 inhibitor lestaurtinib (CEP701) as first-line treatment for older patients with acute myeloid leukemia not considered fit for intensive chemotherapy. Blood 108 (10) , pp. 3262-3270. 10.1182/blood-2006-04-015560

Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Mills, Kenneth I., Gilkes, Amanda F., Austin, Steve J., Walsh, Valerie and Burnett, Alan K. 2006. The effects of lestaurtinib (CEP701) and PKC412 on primary AML blasts: the induction of cytotoxicity varies with dependence on FLT3 signaling in both FLT3-mutated and wild-type cases. Blood 108 (10) , pp. 3494-3503. 10.1182/blood-2006-04-015487

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