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A toolkit for the identification of NEAT1_2/paraspeckle modulators.
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Collins, Ross, Lee, Hyunah, Jones, Dyfyr, Elkins, Jonathan M., Gillespie, Jason A., Thomas, Carys, Baldwin, Alex G. ORCID: https://orcid.org/0000-0002-7126-5220, Jones, Kimberley, Waters, Loren, Paine, Marie, Atack, John R. ORCID: https://orcid.org/0000-0002-3410-791X, Ward, Simon E. ORCID: https://orcid.org/0000-0002-8745-8377, Grubisha, Olivera ORCID: https://orcid.org/0000-0003-1067-1230 and Foley, David W. ORCID: https://orcid.org/0000-0001-8449-4754
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Comparative analysis of small-molecule limk1/2 inhibitors: chemical synthesis, biochemistry, and cellular activity.
Journal of Medicinal Chemistry
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Koulouris, Chloe R., Gardiner, Sian E., Harris, Tessa K., Elvers, Karen T., Mark Roe, S., Gillespie, Jason A., Ward, Simon E. ORCID: https://orcid.org/0000-0002-8745-8377, Grubisha, Olivera ORCID: https://orcid.org/0000-0003-1067-1230, Nicholls, Robert A., Atack, John R. and Bax, Benjamin D.
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Tyrosine 121 moves revealing a ligandable pocket that couples catalysis to ATP-binding in serine racemase.
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Hufgard, Jillian R., Williams, Michael T., Skelton, Matthew R., Grubisha, Olivera ORCID: https://orcid.org/0000-0003-1067-1230, Ferreira, Filipa M., Sanger, Helen, Wright, Mary E., Reed-Kessler, Tracy M., Rasmussen, Kurt, Duman, Ronald S. and Vorhees, Charles V.
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Phosphodiesterase-1b (Pde1b) knockout mice are resistant to forced swim and tail suspension induced immobility and show upregulation of Pde10a.
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Ursu, Daniel, Ebert, Philip, Langron, Emily, Ruble, Cara, Munsie, Leanne, Zou, Wei, Fijal, Bonnie, Qian, Yue-Wei, McNearney, Terry A, Mogg, Adrian, Grubisha, Olivera ORCID: https://orcid.org/0000-0003-1067-1230, Merchant, Kalpana and Sher, Emanuele
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Gain and loss of function of P2X7 receptors: Mechanisms, pharmacology and relevance to diabetic neuropathic pain.
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Grubisha, Olivera ORCID: https://orcid.org/0000-0003-1067-1230, Mogg, Adrian J., Sorge, Jessica L., Ball, Laura-Jayne, Sanger, Helen, Ruble, Cara L. A., Folly, Elizabeth A., Ursu, Daniel and Broad, Lisa M.
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Pharmacological profiling of the TRPV3 channel in recombinant and native assays.
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Sanger, Helen, Hanna, Lydia, Colvin, Ellen M., Grubisha, Olivera ORCID: https://orcid.org/0000-0003-1067-1230, Ursu, Daniel, Heinz, Beverly A., Findlay, Jeremy D., Vivier, Richard G., Sher, Emanuele, Lodge, David, Monn, James A. and Broad, Lisa M.
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Pharmacological profiling of native group II metabotropic glutamate receptors in primary cortical neuronal cultures using a FLIPR.
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Grubisha, Olivera ORCID: https://orcid.org/0000-0003-1067-1230, Kaminska, Monika, Duquerroy, Stéphane, Fontan, Elisabeth, Cordier, Florence, Haouz, Ahmed, Raynal, Bertrand, Chiaravalli, Jeanne, Delepierre, Muriel, Israël, Alain, Véron, Michel and Agou, Fabrice
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DARPin-assisted crystallography of the CC2-LZ domain of NEMO reveals a coupling between dimerization and ubiquitin binding.
Journal of Molecular Biology
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Cordier, Florence, Grubisha, Olivera ORCID: https://orcid.org/0000-0003-1067-1230, Traincard, François, Véron, Michel, Delepierre, Muriel and Agou, Fabrice
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The zinc finger of NEMO is a functional ubiquitin-binding domain.
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Grubisha, Olivera ORCID: https://orcid.org/0000-0003-1067-1230, Rafty, Louise A., Takanishi, Christina L., Xu, Xiaojie, Tong, Lei, Perraud, Anne-Laure, Scharenberg, Andrew M. and Denu, John M.
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Metabolite of SIR2 reaction modulates TRPM2 Ion channel.
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Grubisha, Olivera ORCID: https://orcid.org/0000-0003-1067-1230, Smith, Brian C. and Denu, John M.
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Small molecule regulation of Sir2 protein deacetylases.
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Grubisha, Olivera ORCID: https://orcid.org/0000-0003-1067-1230 and Traktman, P.
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Genetic analysis of the vaccinia virus I6 telomere-binding protein uncovers a key role in genome encapsidation.
Journal of Virology
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Punjabi, A., Boyle, K., DeMasi, J., Grubisha, O. ORCID: https://orcid.org/0000-0003-1067-1230, Unger, B., Khanna, M. and Traktman, P.
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Clustered charge-to-alanine mutagenesis of the vaccinia virus A20 gene: Temperature-sensitive mutants have a DNA-minus phenotype and are defective in the production of processive DNA polymerase activity.
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Derrien, M., Punjabi, A., Khanna, M., Grubisha, Olivera ORCID: https://orcid.org/0000-0003-1067-1230 and Traktman, P.
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Tyrosine phosphorylation of A17 during vaccinia virus infection: involvement of the H1 phosphatase and the F10 kinase.
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