Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Browse by All Cardiff Authors

[up] Up a level
Number of items: 23.

Thanassoulas, Angelos, Swann, Karl ORCID: https://orcid.org/0000-0002-4355-1449, Lai, F Anthony ORCID: https://orcid.org/0000-0003-2852-8547 and Nomikos, Michail 2022. Sperm factors and egg activation: the structure and function relationship of sperm plcz1. Reproduction 164 (1) , F1-F8. 10.1530/REP-21-0477

Nomikos, Michail, Kashir, Junaid and Lai, Francis Antony ORCID: https://orcid.org/0000-0003-2852-8547 2017. The role and mechanism of action of sperm PLC-zeta in mammalian fertilisation. Biochemical Journal 474 (21) , pp. 3659-3673. 10.1042/BCJ20160521
file

Nomikos, Michail, Swann, Karl ORCID: https://orcid.org/0000-0002-4355-1449 and Lai, Francis Anthony ORCID: https://orcid.org/0000-0003-2852-8547 2017. Fundamental role for sperm phospholipase C ζ in mammalian fertilization. De Jonge, Christopher J. and Barratt, Christopher L. R., eds. The Sperm Cell, Cambridge: Cambridge University Press, pp. 177-192. (10.1017/9781316411124.014)

Nomikos, Michail, Stamatiadis, Panagiotis, Sanders, Jessica Rose, Beck, Konrad ORCID: https://orcid.org/0000-0001-5098-9484, Calver, Brian Lewis, Buntwal, Luke, Lofty, Morgan, Sideratou, Zili, Swann, Karl ORCID: https://orcid.org/0000-0002-4355-1449 and Lai, Francis Anthony ORCID: https://orcid.org/0000-0003-2852-8547 2017. Male infertility-linked point mutation reveals a vital binding role for the C2 domain of sperm PLCζ. Biochemical Journal 474 (6) , pp. 1003-1016. 10.1042/BCJ20161057
file

Kashir, Junaid, Buntwal, Luke, Nomikos, Michail, Calver, Brian L., Stamatiadis, Panagiotis, Ashley, Peter, Vassilakopoulou, Vyronia, Sanders, David, Knaggs, Paul, Livaniou, Evangelia, Bunkheila, Adnan, Swann, Karl ORCID: https://orcid.org/0000-0002-4355-1449 and Lai, Francis Anthony ORCID: https://orcid.org/0000-0003-2852-8547 2017. Antigen unmasking enhances visualization efficacy of the oocyte activation factor, phospholipase C zeta, in mammalian sperm. Molecular Human Reproduction 23 (1) , pp. 54-67. 10.1093/molehr/gaw073
file

Nomikos, Michail, Thanassoulas, Angelos, Beck, Konrad ORCID: https://orcid.org/0000-0001-5098-9484, Theodoridou, Maria, Kew, Jasmine, Kashir, Junaid, Calver, Brian Lewis, Matthews, Emily, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Sideratou, Zili, Nounesis, George and Lai, Francis Anthony ORCID: https://orcid.org/0000-0003-2852-8547 2016. Mutations in PLCd1 associated with hereditary leukonychia display divergent PIP2 hydrolytic function. FEBS Journal 283 (24) , pp. 4502-4514. 10.1111/febs.13939
file

Nomikos, Michail, Sanders, Jessica Rose, Parthimos, Dimitris ORCID: https://orcid.org/0000-0003-3852-323X, Buntwal, Luke, Calver, Brian Lewis, Stamatiadis, Panagiotis, Smith, Adrian, Clue, Matthew, Sideratou, Zili, Swann, Karl ORCID: https://orcid.org/0000-0002-4355-1449 and Lai, Francis Anthony ORCID: https://orcid.org/0000-0003-2852-8547 2015. Essential role of the EF-hand domain in targeting sperm phospholipase Cζ to membrane phosphatidylinositol 4,5-bisphosphate (PIP2). Journal of Biological Chemistry 290 (49) , pp. 29519-29530. 10.1074/jbc.M115.658443
file

Vassilakopoulou, Vyronia, Calver, Brian, Thanassoulas, Angelos, Beck, Konrad ORCID: https://orcid.org/0000-0001-5098-9484, Hu, Handan, Buntwal, Luke, Smith, Adrian, Theodoridou, Maria, Kashir, Junaid, Blayney, Lynda, Livaniou, Evangelia, Nounesis, George, Lai, Francis ORCID: https://orcid.org/0000-0003-2852-8547 and Nomikos, Michail 2015. Distinctive malfunctions of calmodulin mutations associated with heart RyR2-mediated arrhythmic disease. Biochimica et Biophysica Acta (BBA) - General Subjects 1850 (11) , pp. 2168-2176. 10.1016/j.bbagen.2015.07.001

Sanusi, Randa, Yu, Yuansong, Nomikos, Michail, Lai, F. Anthony ORCID: https://orcid.org/0000-0003-2852-8547 and Swann, Karl ORCID: https://orcid.org/0000-0002-4355-1449 2015. Rescue of failed oocyte activation after ICSI in a mouse model of male factor infertility by recombinant phospholipase Cζ. Molecular Human Reproduction 21 (10) , pp. 783-791. 10.1093/molehr/gav042
file

Nomikos, Michail, Sanders, Jessica R., Kashir, Junaid, Sanusi, Randa, Buntwal, Luke, Love, Daniel, Ashley, Peter, Sanders, David, Knaggs, Paul, Bunkheila, Adnan, Swann, Karl ORCID: https://orcid.org/0000-0002-4355-1449 and Lai, Francis ORCID: https://orcid.org/0000-0003-2852-8547 2015. Functional disparity between human PAWP and PLCζ in the generation of Ca2+ oscillations for oocyte activation. Molecular Human Reproduction 21 (9) , pp. 702-710. 10.1093/molehr/gav034

Kashir, Junaid, Nomikos, Michail, Swann, Karl ORCID: https://orcid.org/0000-0002-4355-1449 and Lai, Francis ORCID: https://orcid.org/0000-0003-2852-8547 2015. PLCζ or PAWP: revisiting the putative mammalian sperm factor that triggers egg activation and embryogenesis. Molecular Human Reproduction 21 (5) , pp. 383-388. 10.1093/molehr/gav009

Nomikos, Michail, Swann, Karl ORCID: https://orcid.org/0000-0002-4355-1449 and Lai, Francis Anthony ORCID: https://orcid.org/0000-0003-2852-8547 2015. Is PAWP the 'real' sperm factor? Asian Journal of Andrology 17 (3) , pp. 444-446. 10.4103/1008-682X.142145

Nomikos, Michail, Sanders, Jessica Rose, Theodoridou, Maria, Kashir, Junaid, Matthews, Emily, Nounesis, George, Lai, Francis ORCID: https://orcid.org/0000-0003-2852-8547 and Swann, Karl ORCID: https://orcid.org/0000-0002-4355-1449 2014. Sperm-specific post-acrosomal WW-domain binding protein (PAWP) does not cause Ca2+ release in mouse oocytes. Molecular Human Reproduction 20 (10) , pp. 938-947. 10.1093/molehr/gau056

Nomikos, Michail, Thanassoulas, Angelos, Beck, Konrad ORCID: https://orcid.org/0000-0001-5098-9484, Vassilakopoulou, Vyronia, Hu, Handan, Calver, Brian Lewis, Theodoridou, Maria, Kashir, Junaid, Blayney, Lynda Mary, Livaniou, Evangelia, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Nounesis, George and Lai, Francis Anthony ORCID: https://orcid.org/0000-0003-2852-8547 2014. Altered RyR2 regulation by the calmodulin F90L mutation associated with idiopathic ventricular fibrillation and early sudden cardiac death. Febs Letters 588 (17) , pp. 2898-2902. 10.1016/j.febslet.2014.07.007

Kashir, Junaid, Nomikos, Michail, Lai, Francis ORCID: https://orcid.org/0000-0003-2852-8547 and Swann, Karl ORCID: https://orcid.org/0000-0002-4355-1449 2014. Sperm-induced Ca2+ release during egg activation in mammals. Biochemical and Biophysical Research Communications 450 (3) , pp. 1204-1211. 10.1016/j.bbrc.2014.04.078

Nomikos, Michail, Theodoridou, Maria, Elgmati, Khalil, Parthimos, Dimitris ORCID: https://orcid.org/0000-0003-3852-323X, Calver, Brian L., Buntwal, Luke, Nounesis, George, Swann, Karl ORCID: https://orcid.org/0000-0002-4355-1449 and Lai, F. Anthony ORCID: https://orcid.org/0000-0003-2852-8547 2014. Human PLCζ exhibits superior fertilization potency over mouse PLCζ in triggering the Ca2+ oscillations required for mammalian oocyte activation. Molecular Human Reproduction 20 (6) , pp. 489-498. 10.1093/molehr/gau011

Gonzalez-Garcia, Jose Raul, Bradley, Josephine, Nomikos, Michail, Paul, Laboni, Machaty, Zoltan, Lai, F. Anthony ORCID: https://orcid.org/0000-0003-2852-8547 and Swann, Karl ORCID: https://orcid.org/0000-0002-4355-1449 2014. The dynamics of MAPK inactivation at fertilization in mouse eggs. Journal of Cell Science 127 (12) , pp. 2749-2760. 10.1242/jcs.145045
file

Theodoridou, Maria, Nomikos, Michail, Parthimos, Dimitris ORCID: https://orcid.org/0000-0003-3852-323X, Gonzalez-Garcia, J., Elgmati, K., Calver, Brian Lewis, Sideratou, Z., Nounesis, G., Swann, Karl ORCID: https://orcid.org/0000-0002-4355-1449 and Lai, Francis Anthony ORCID: https://orcid.org/0000-0003-2852-8547 2013. Chimeras of sperm PLCζ reveal disparate protein domain functions in the generation of intracellular Ca2+ oscillations in mammalian eggs at fertilization. Molecular Human Reproduction 19 (12) , pp. 852-864. 10.1093/molehr/gat070

Blayney, Lynda Mary, Beck, Konrad ORCID: https://orcid.org/0000-0001-5098-9484, MacDonald, Ewan, D'Cruz, Leon G,, Nomikos, Michail, Griffiths, Julia, Thanassoulas, Angelos, Nounesis, George and Lai, Francis Anthony ORCID: https://orcid.org/0000-0003-2852-8547 2013. ATP interacts with the CPVT mutation-associated central domain of the cardiac ryanodine receptor. Biochimica et Biophysica Acta (BBA) - General Subjects 1830 (10) , pp. 4426-4432. 10.1016/j.bbagen.2013.05.038

Nomikos, Michail, Yu, Yuansong, Elgmati, Khalil, Theodoridou, Maria, Campbell, Karen, Vassilakopoulou, Vyronia, Zikos, Christos, Livaniou, Evangelia, Amso, Nazar Najib ORCID: https://orcid.org/0000-0002-8646-6623, Nounesis, George, Swann, Karl ORCID: https://orcid.org/0000-0002-4355-1449 and Lai, Francis Anthony ORCID: https://orcid.org/0000-0003-2852-8547 2013. Phospholipase Cζ rescues failed oocyte activation in a prototype of male factor infertility. Fertility and Sterility 99 (1) , pp. 76-85. 10.1016/j.fertnstert.2012.08.035

Nomikos, Michail, Elgmati, Khalil, Theodoridou, Maria, Calver, Brian Lewis, Cumbes, Bevan ORCID: https://orcid.org/0000-0001-8529-0040, Nounesis, George, Swann, Karl ORCID: https://orcid.org/0000-0002-4355-1449 and Lai, Francis Anthony ORCID: https://orcid.org/0000-0003-2852-8547 2011. Male infertility-linked point mutation disrupts the Ca2+oscillation-inducing and PIP2hydrolysis activity of sperm PLCζ. Biochemical Journal 434 (2) , pp. 211-217. 10.1042/BJ20101772

Nomikos, Michail, Elgmati, Khalil, Theodoridou, Maria, Calver, Brian Lewis, Cumbes, Bevan ORCID: https://orcid.org/0000-0001-8529-0040, Nounesis, George, Swann, Karl ORCID: https://orcid.org/0000-0002-4355-1449 and Lai, Francis Anthony ORCID: https://orcid.org/0000-0003-2852-8547 2011. Male infertility-linked point mutation disrupts the Ca2+ oscillation-inducing and PIP2 hydrolysis activity of sperm PLCζ [Erratum]. The Biochemical Journal 435 (3) , p. 791.

Nomikos, Michail 2005. Molecular and enzymatic characterization of mammalian phospholipase C zeta (PLCϚ). PhD Thesis, Cardiff University.
file

This list was generated on Tue Apr 15 08:44:28 2025 BST.


Maintained by Cardiff University Information Services