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Number of items: 13.

Pasqualetto, Gaia, Mack, Andrew, Lewis, Emily, Cooper, Ryan, Holland, Alistair, Borucu, Ufuk, Mantell, Judith, Davies, Tom, Weckener, Miriam, Clare, Dan, Green, Tom, Kille, Pete ORCID: https://orcid.org/0000-0001-6023-5221, Muhlhozl, Alex and Young, Mark T. ORCID: https://orcid.org/0000-0002-9615-9002 2023. CryoEM structure and Alphafold molecular modelling of a novel molluscan hemocyanin. PLoS ONE 18 (6) , e0287294. 10.1371/journal.pone.0287294
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Pasqualetto, Gaia, Zuanon, Marika, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 and Young, Mark T ORCID: https://orcid.org/0000-0002-9615-9002 2023. Identification of the molecular determinants of antagonist potency in the allosteric binding pocket of human P2X4. Frontiers in Pharmacology 14 10.3389/fphar.2023.1101023
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Pasqualetto, Gaia, Zuanon, Marika, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 and Young, Mark T. ORCID: https://orcid.org/0000-0002-9615-9002 2023. Identification of a novel P2X7 antagonist using structure-based virtual screening. Frontiers in Pharmacology 13 , 1094607. 10.3389/fphar.2022.1094607
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Picarazzi, Francesca, Zuanon, Marika, Pasqualetto, Gaia, Cammarone, Silvia, Romeo, Isabella, Young, Mark T. ORCID: https://orcid.org/0000-0002-9615-9002, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868 and Mori, Mattia 2022. Identification of small molecular chaperones binding p23h mutant opsin through an in silico structure-based approach. Journal of Chemical Information and Modeling 62 (22) , pp. 5794-5805. 10.1021/acs.jcim.2c01040
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Pasqualetto, Gaia, Pileggi, Elisa, Schepelmann, Martin ORCID: https://orcid.org/0000-0002-7017-5426, Varricchio, Carmine ORCID: https://orcid.org/0000-0002-1673-4768, Rozanowska, Malgorzata ORCID: https://orcid.org/0000-0003-2913-8954, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 and Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868 2021. Ligand-based rational design, synthesis and evaluation of novel potential chemical chaperones for opsin. European Journal of Medicinal Chemistry 226 , 113841. 10.1016/j.ejmech.2021.113841
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Grimes, Leanne, Griffiths, Julia, Pasqualetto, Gaia, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Kemp, Paul J. ORCID: https://orcid.org/0000-0003-2773-973X, Young, Mark T. ORCID: https://orcid.org/0000-0002-9615-9002 and van der Goes van Naters, Wynand ORCID: https://orcid.org/0000-0002-6808-0161 2020. Drosophila taste neurons as an agonist-screening platform for P2X receptors. Scientific Reports 10 , 8292. 10.1038/s41598-020-65169-9
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Pasqualetto, Gaia, Schepelmann, Martin ORCID: https://orcid.org/0000-0002-7017-5426, Varricchio, Carmine ORCID: https://orcid.org/0000-0002-1673-4768, Pileggi, Elisa, Khogali, Caroline, Morgan, Siân R., Boostrom, Ian, Rozanowska, Malgorzata ORCID: https://orcid.org/0000-0003-2913-8954, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Ferla, Salvatore ORCID: https://orcid.org/0000-0002-5918-9237 and Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868 2020. Computational studies towards the identification of novel rhodopsin-binding compounds as chemical chaperones for misfolded opsins. Molecules 25 (21) , 4904. 10.3390/molecules25214904
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Giancotti, Gilda, Rigo, Ilaria, Pasqualetto, Gaia, Young, Mark T. ORCID: https://orcid.org/0000-0002-9615-9002, Neyts, Johan, Rocha-Pereira, Joana, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Ferla, Salvatore ORCID: https://orcid.org/0000-0002-5918-9237 and Bassetto, Marcella 2019. A new antiviral scaffold for human norovirus identified with computer-aided approaches on the viral polymerase. Scientific Reports 9 (1) , 18413. 10.1038/s41598-019-54903-7
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Pasqualetto, Gaia, Pileggi, Elisa, Schepelmann, Martin ORCID: https://orcid.org/0000-0002-7017-5426, Heard, Charles ORCID: https://orcid.org/0000-0001-9703-9777, Young, Mark Thomas ORCID: https://orcid.org/0000-0002-9615-9002, Rozanowska, Malgorzata B. ORCID: https://orcid.org/0000-0003-2913-8954, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 and Bassetto, Marcella 2019. Novel small-molecule chaperones to overcome opsin misfolding, mistrafficking and aggregation in retinal blinding diseases. Presented at: 2019 ARVO Annual Meeting, Vancouver, Canada, 28 April - 02 May 2019. Investigative ophthalmology & visual science. , vol.60 (9) ARVO,

Pileggi, Elisa, Pasqualetto, Gaia, Rozanowska, Malgorzata ORCID: https://orcid.org/0000-0003-2913-8954, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 and Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868 2019. Development of novel treatments against inherited blinding diseases Retinitis pigmentosa and Leber's congenital amaurosis [Abstract]. Abstracts of Papers of the American Chemical Society 257 , 318.

Pasqualetto, Gaia 2018. Structure-based design of P2X receptor small molecule modulators. PhD Thesis, Cardiff University.
Item availability restricted.
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Pasqualetto, Gaia, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 and Young, Mark T. ORCID: https://orcid.org/0000-0002-9615-9002 2018. The molecular determinants of small-molecule ligand binding at P2X receptors. Frontiers in Pharmacology 9 , 58. 10.3389/fphar.2018.00058
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Anthopoulos, Athanasios, Pasqualetto, Gaia, Grimstead, Ian and Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 2014. Haptic-driven, interactive drug design: implementing a GPU-based approach to evaluate the induced fit effect. Faraday Discussions 169 , pp. 323-342. 10.1039/C3FD00139C
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This list was generated on Fri Dec 20 05:35:19 2024 GMT.


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