ORCA
Online Research @ Cardiff
Browse by Current Cardiff authors
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Up a levelNumber of items: 107.
Lohana, Parkash, Suryaprawira, Albert, Woods, Emma L., Dally, Jordanna, Gait-Carr, Edward, Alaidaroos, Nadia Y.A., Heard, Charles M.  ORCID: https://orcid.org/0000-0001-9703-9777, Lee, Kwok Y., Ruge, Fiona, Farrier, Jeremy N., Enoch, Stuart, Caley, Matthew P., Peake, Matthew A., Davies, Lindsay C. ORCID: https://orcid.org/0000-0002-4876-6270, Giles, Peter J. ORCID: https://orcid.org/0000-0003-3143-6854, Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820, Stephens, Phil ORCID: https://orcid.org/0000-0002-0840-4996 and Moseley, Ryan ORCID: https://orcid.org/0000-0002-2812-6735
2023.
Role of enzymic antioxidants in mediating oxidative stress and contrasting wound healing capabilities in oral mucosal/skin fibroblasts and tissues.
Antioxidants
12
(7)
, 1374.
10.3390/antiox12071374
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Bergonzi, Maria Camilla, Heard, Charles M. ORCID: https://orcid.org/0000-0001-9703-9777 and Garcia-Pardo, Javier
2022.
Bioactive molecules from plants: discovery and pharmaceutical applications.
Pharmaceutics
14
(10)
, 2116.
10.3390/pharmaceutics14102116
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Wong, Anepmete, Fallon, Melissa, Celiksoy, Vildan, Ferla, Salvatore, Varricchio, Carmine ORCID: https://orcid.org/0000-0002-1673-4768, Whitaker, David ORCID: https://orcid.org/0000-0002-8271-7552, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 and Heard, Charles M. ORCID: https://orcid.org/0000-0001-9703-9777
2022.
A composite system based upon hydroxypropyl cyclodextrins and soft hydrogel contact lenses for the delivery of therapeutic doses of econazole to the cornea, in vitro.
Pharmaceutics
14
(8)
, e1631.
10.3390/pharmaceutics14081631
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Alrashidi, Amal, Jafar, Mohammed, Higgins, Niamh, Mulligan, Ciara, Varricchio, Carmine ORCID: https://orcid.org/0000-0002-1673-4768, Moseley, Ryan ORCID: https://orcid.org/0000-0002-2812-6735, Celiksoy, Vildan, Houston, David MJ and Heard, Charles M ORCID: https://orcid.org/0000-0001-9703-9777
2021.
A time-kill assay study on the synergistic bactericidal activity of pomegranate rind extract and Zn (II) against
Methicillin-resistant Staphylococcus aureus (MRSA), Staphylococcus epidermidis, Escherichia coli, and Pseudomonas aeruginosa.
Biomolecules
11
(12)
, 1889.
10.3390/biom11121889
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Yonbawi, Ahmed R., Abdallah, Hossam M., Alkhilaiwi, Faris A., Koshak, Abdulrahman E. and Heard, Charles M. ORCID: https://orcid.org/0000-0001-9703-9777
2021.
Anti-Proliferative, Cytotoxic and Antioxidant Properties of the Methanolic Extracts of Five Saudi Arabian Flora with Folkloric Medicinal Use: Aizoon canariense, Citrullus colocynthis, Maerua crassifolia, Rhazya stricta and Tribulus macropterus.
Plants
10
(10)
, 2073.
10.3390/plants10102073
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Varricchio, Carmine ORCID: https://orcid.org/0000-0002-1673-4768, Beirne, Kathy, Aeschlimann, Pascale, Heard, Charles ORCID: https://orcid.org/0000-0001-9703-9777, Rozanowska, Malgorzata ORCID: https://orcid.org/0000-0003-2913-8954, Votruba, Marcela ORCID: https://orcid.org/0000-0002-7680-9135 and Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419
2020.
Discovery of Novel 2-Aniline-1,4-naphthoquinones as potential new drug treatment for Leber’s hereditary optic neuropathy (LHON).
Journal of Medicinal Chemistry
63
(22)
, 13638 -13655.
10.1021/acs.jmedchem.0c00942
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Heard, Charles M. ORCID: https://orcid.org/0000-0001-9703-9777
2020.
An ex vivo skin model to probe modulation of local cutaneous arachidonic acid inflammation pathway.
Journal of Biological Methods
7
(4)
, e138.
10.14440/jbm.2020.319
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Celiksoy, Vildan, Moses, Rachael L., Sloan, Alastair J., Moseley, Ryan ORCID: https://orcid.org/0000-0002-2812-6735 and Heard, Charles M. ORCID: https://orcid.org/0000-0001-9703-9777
2020.
Evaluation of the in vitro oral wound healing effects of pomegranate (Punica granatum) rind extract and punicalagin, in combination with Zn (II).
Biomolecules
10
(9)
, 1234.
10.3390/biom10091234
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Varricchio, C. ORCID: https://orcid.org/0000-0002-1673-4768, Beirne, K., Heard, C. ORCID: https://orcid.org/0000-0001-9703-9777, Newland, B. ORCID: https://orcid.org/0000-0002-5214-2604, Rozanowska, M. ORCID: https://orcid.org/0000-0003-2913-8954, Brancale, A. ORCID: https://orcid.org/0000-0002-9728-3419 and Votruba, M. ORCID: https://orcid.org/0000-0002-7680-9135
2020.
The ying and yang of idebenone: Not too little, not too much - cell death in NQO1 deficient cells and the mouse retina.
Free Radical Biology and Medicine
152
, pp. 551-560.
10.1016/j.freeradbiomed.2019.11.030
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Bender, Lena, Boostrom, Hannah M. ORCID: https://orcid.org/0000-0002-7367-3631, Varricchio, Carmine ORCID: https://orcid.org/0000-0002-1673-4768, Zuanon, Marika, Celiksoy, Vildan, Sloan, Alastair ORCID: https://orcid.org/0000-0002-1791-0903, Cowpe, Jonathan and Heard, Charles M ORCID: https://orcid.org/0000-0001-9703-9777
2020.
A novel dual action monolithic thermosetting hydrogel loaded with lidocaine and metronidazole as a potential treatment for alveolar osteitis.
European Journal of Pharmaceutics and Biopharmaceutics
149
, pp. 85-94.
10.1016/j.ejpb.2020.01.007
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Morgan, Sian R., Pilia, Nicole, Hewitt, Melissa, Moses, Rachael L., Moseley, Ryan ORCID: https://orcid.org/0000-0002-2812-6735, Lewis, Philip N. ORCID: https://orcid.org/0000-0002-3353-0708, Morrison, Peter W. J. ORCID: https://orcid.org/0000-0002-3712-7908, Kelly, Steven L., Parker, Josie E., Whitaker, David ORCID: https://orcid.org/0000-0002-8271-7552, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 and Heard, Charles M. ORCID: https://orcid.org/0000-0001-9703-9777
2020.
Controlled in vitro delivery of voriconazole and diclofenac to the cornea using contact lenses for the treatment of Acanthamoeba keratitis.
International Journal of Pharmaceutics
579
, 119102.
10.1016/j.ijpharm.2020.119102
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Hewitt, Melissa G., Morrison, Peter W. J. ORCID: https://orcid.org/0000-0002-3712-7908, Boostrom, Hannah M. ORCID: https://orcid.org/0000-0002-7367-3631, Morgan, Siân R., Fallon, Melissa ORCID: https://orcid.org/0000-0002-0267-3829, Lewis, Philip N. ORCID: https://orcid.org/0000-0002-3353-0708, Whitaker, David ORCID: https://orcid.org/0000-0002-8271-7552, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Varricchio, Carmine ORCID: https://orcid.org/0000-0002-1673-4768, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120, Burton, Matthew J. and Heard, Charles M. ORCID: https://orcid.org/0000-0001-9703-9777
2020.
In Vitro Topical Delivery of Chlorhexidine to the Cornea: Enhancement Using Drug-Loaded Contact Lenses and β-Cyclodextrin Complexation, and the Importance of Simulating Tear Irrigation.
Molecular Pharmaceutics
17
(4)
, pp. 1428-1441.
10.1021/acs.molpharmaceut.0c00140
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Yee Lim, Sim, Dafydd, Mali, Ong, Jee, Ord-McDermott, Launa A., Board-Davies, Emma, Sands, Kirsty, Williams, David ORCID: https://orcid.org/0000-0002-7351-5131, Sloan, Alastair J. ORCID: https://orcid.org/0000-0002-1791-0903 and Heard, Charles M. ORCID: https://orcid.org/0000-0001-9703-9777
2020.
Mucoadhesive thin films for the simultaneous delivery of microbicide and anti-inflammatory drugs in the treatment of periodontal diseases.
International Journal of Pharmaceutics
573
, 118860.
10.1016/j.ijpharm.2019.118860
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Pasqualetto, Gaia, Pileggi, Elisa, Schepelmann, Martin ORCID: https://orcid.org/0000-0002-7017-5426, Heard, Charles ORCID: https://orcid.org/0000-0001-9703-9777, Young, Mark Thomas ORCID: https://orcid.org/0000-0002-9615-9002, Rozanowska, Malgorzata B. ORCID: https://orcid.org/0000-0003-2913-8954, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 and Bassetto, Marcella
2019.
Novel small-molecule chaperones to overcome opsin misfolding, mistrafficking and aggregation in retinal blinding diseases.
Presented at: 2019 ARVO Annual Meeting,
Vancouver, Canada,
28 April - 02 May 2019.
Investigative ophthalmology & visual science.
, vol.60
(9)
ARVO,
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Barbieri, Mirko and Heard, Charles M. ORCID: https://orcid.org/0000-0001-9703-9777
2019.
Isolation of punicalagin from Punica granatum rind extract using mass-directed semi-preparative ESI-AP single quadrupole LC-MS.
Journal of Pharmaceutical and Biomedical Analysis
166
, pp. 90-94.
10.1016/j.jpba.2018.12.033
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Yurdasiper, Aysu, Ertan, Gokhan and Heard, Charles M. ORCID: https://orcid.org/0000-0001-9703-9777
2018.
Enhanced delivery of naproxen to the viable epidermis from an activated poly N-isopropylacrylamide (PNIPAM) Nanogel: Skin penetration, modulation of COX-2 expression and rat paw Oedema.
Nanomedicine: Nanotechnology, Biology and Medicine
14
(7)
, pp. 2051-2059.
10.1016/j.nano.2018.05.017
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Davison, Zoë, Nicholson, Robert I., Hiscox, Stephen ORCID: https://orcid.org/0000-0003-0105-2702 and Heard, Charles M. ORCID: https://orcid.org/0000-0001-9703-9777
2018.
Co-administration of fish oil with signal transduction inhibitors has anti-migration effects in breast cancer cell lines, in vitro.
The Open Biochemistry Journal
12
(1)
, pp. 130-148.
10.2174/1874091X01812010130
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Zulfakar, Mohd Hanif, Chan, Lee Mei, Rehman, Khurram, Wai, Lam Kok and Heard, Charles ORCID: https://orcid.org/0000-0001-9703-9777
2018.
Coenzyme Q10-loaded fish oil-based Bigel System: probing the delivery across porcine skin and possible interaction with fish oil fatty acids.
AAPS PharmSciTech
19
(3)
, pp. 1116-1123.
10.1208/s12249-017-0923-x
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Houston, David M. J., Bugert, Joachim J. ORCID: https://orcid.org/0000-0002-0556-3211, Denyer, Stephen P. and Heard, Charles M. ORCID: https://orcid.org/0000-0001-9703-9777
2017.
Potentiated virucidal activity of pomegranate rind extract (PRE) and punicalagin against Herpes simplex virus (HSV) when co-administered with zinc (II) ions, and antiviral activity of PRE against HSV and aciclovir-resistant HSV.
PLoS ONE
12
(6)
, e0179291.
10.1371/journal.pone.0179291
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Houston, David, Bugert, Joachim ORCID: https://orcid.org/0000-0002-0556-3211, Denyer, Stephen P. and Heard, Charles M. ORCID: https://orcid.org/0000-0001-9703-9777
2017.
Anti-inflammatory activity of Punica granatum L. (Pomegranate) rind extracts applied topically to ex vivo skin.
European Journal of Pharmaceutics and Biopharmaceutics
112
, pp. 30-37.
10.1016/j.ejpb.2016.11.014
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Houston, David M. J., Robins, Bethan, Bugert, Joachim J., Denyer, Stephen P. and Heard, Charles M. ORCID: https://orcid.org/0000-0001-9703-9777
2017.
In vitro permeation and biological activity of punicalagin and zinc (II) across skin and mucous membranes prone to Herpes simplex virus infection.
European Journal of Pharmaceutical Sciences
96
, pp. 99-106.
10.1016/j.ejps.2016.08.013
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Chan, Wendy, Akhbanbetova, Alina, Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 and Heard, Charles M. ORCID: https://orcid.org/0000-0001-9703-9777
2016.
Topical delivery of a Rho-kinase inhibitor to the cornea via mucoadhesive film.
European Journal of Pharmaceutical Sciences
91
, pp. 256-264.
10.1016/j.ejps.2016.05.016
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Zulfakar, Mohd Hanif, Porter, Rebecca and Heard, Charles ORCID: https://orcid.org/0000-0001-9703-9777
2016.
In vivoresponse of GsdmA3Dfl/+ mice to topically applied fish oil - effects on cellular markers and macrophages.
FEBS Open Bio
6
(8)
, pp. 827-834.
10.1002/2211-5463.12095
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Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2015.
Ethanol and other alcohols: old enhancers, alternative perspectives.
Dragicevic, Nina and Maibach, Howard I., eds.
Percutaneous Penetration Enhancers Chemical Methods in Penetration Enhancement: Modification of the Stratum Corneum,
Springer,
pp. 151-172.
(10.1007/978-3-662-47039-8_10)
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Abu Samah, Nor Hayati and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2014.
The effects of topically applied polyNIPAM-based nanogels and their monomers on skin cyclooxygenase expression,ex vivo.
Nanotoxicology
8
(1)
, pp. 100-106.
10.3109/17435390.2012.754511
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Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777 and Brain, Keith Roger
2014.
Chiral separations.
Street, G., ed.
Highly selective separations in biotechnology,
London:
Blackie Academic and Professional,
pp. 179-206.
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Lau, Wing Man, Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777 and White, Alex William ORCID: https://orcid.org/0000-0002-1539-0158
2013.
Design, synthesis and in vitro degradation of a novel co-drug for the treatment of psoriasis.
Pharmaceutics
5
(2)
, pp. 232-245.
10.3390/pharmaceutics5020232
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Abu Samah, Nor Hayati and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2013.
Enhanced in vitro transdermal delivery of caffeine using a temperature- and pH-sensitive nanogel, poly(NIPAM-co-AAc).
International Journal of Pharmaceutics
453
(2)
, pp. 630-640.
10.1016/j.ijpharm.2013.05.042
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Wallace, Eleri, Ong, Charlene M. Y. and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2012.
Delivery of atovaquone and proguanil across sublingual membranes, in vitro.
Pharmaceutical Development and Technology
17
(6)
, pp. 770-776.
10.3109/10837450.2011.580760
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Lau, Wing Man, Ng, Keng Wooi, Sakenyte, Kristina and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2012.
Distribution of esterase activity in porcine ear skin, and the effects of freezing and heat separation.
International Journal of Pharmaceutics
433
(1-2)
, pp. 10-15.
10.1016/j.ijpharm.2012.04.079
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Zulfakar, Mohd Hanif, Ong, Charlene M.Y and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2012.
The effects of betamethasone dipropionate and fish oil on HaCaT proliferation and apoptosis.
International Journal of Pharmaceutics
434
(1-2)
, pp. 399-405.
10.1016/j.ijpharm.2012.06.008
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Abu Samah, Nor Hayati and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2011.
Topically applied KTTKS: a review.
International Journal of Cosmetic Science
33
(6)
, pp. 483-490.
10.1111/j.1468-2494.2011.00657.x
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Zulfakar, Mohd Hanif, Alex, Aneesh, Povazay, Boris, Drexler, Wolfgang, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Porter, Rebecca M. ORCID: https://orcid.org/0000-0001-6748-0916 and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2011.
In vivo response of GsdmA3Dfl/+ mice to topically applied anti-psoriatic agents: effects on epidermal thickness, as determined by optical coherence tomography and H&E staining.
Experimental Dermatology
20
(3)
, pp. 269-272.
10.1111/j.1600-0625.2010.01233.x
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Lau, Wing Man ORCID: https://orcid.org/0000-0002-2998-6470, Ng, Keng Wooi ORCID: https://orcid.org/0000-0003-2541-4763, White, Alex William ORCID: https://orcid.org/0000-0002-1539-0158 and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2011.
Therapeutic and cytotoxic effects of the novel antipsoriasis codrug, naproxyl-dithranol, on HaCaT cells.
Molecular Pharmaceutics
8
(6)
, pp. 2398-2407.
10.1021/mp200327k
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Singka, Gillian S. L., Abu Samah, Nor H., Zulfakar, Mohd, Yurdasiper, A. and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2010.
Enhanced topical delivery and anti-inflammatory activity of methotrexate from an activated nanogel.
European Journal of Pharmaceutics and Biopharmaceutics
76
(2)
, pp. 275-281.
10.1016/j.ejpb.2010.06.014
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Davison, Zoë, Nicholson, Robert I., Denyer, Stephen P. and Heard, Charles M. ORCID: https://orcid.org/0000-0001-9703-9777
2010.
A novel diffusion cell model for the in vitro assessment of transcutaneous breast cancer therapeutics: effect of permeants on MCF-7 cells cultured within the receptor compartment.
European Journal Of Pharmaceutics and Biopharmaceutics
75
(3)
, pp. 411-417.
10.1016/j.ejpb.2010.03.019
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Lau, Wing Man ORCID: https://orcid.org/0000-0002-2998-6470, White, Alex William ORCID: https://orcid.org/0000-0002-1539-0158, Donaldson, M. and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2010.
Histochemical visualisation of esterase activity in porcine ear skin.
Journal of Pharmacy and Pharmacology
62
(6)
, p. 798.
10.1211/jpp.62.06.0016
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Searby, Caroline, Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777 and Porter, Rebecca Mary ORCID: https://orcid.org/0000-0001-6748-0916
2010.
Sonic hedgehog is not enough to create basal cell carcinoma in vitro.
British Journal of Dermatology
162
(4)
, p. 923.
10.1111/j.1365-2133.2010.09700.x
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Abdelouahab, Nassima and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2010.
Estimation of the Relative Antiinflammatory Efficacies of Six Commercial Preparations of Harpagophytum procumbens (Devil's Claw).
Phytotherapy Research
24
(3)
, pp. 333-338.
10.1002/ptr.2930
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Ballam, L. and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2010.
Pre-Treatment with Aloe vera Juice Does Not Enhance the in vitro Permeation of Ketoprofen across Skin.
Skin Pharmacology and Physiology
23
(2)
, pp. 113-116.
10.1159/000265682
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Lee, L. M., Davison, Zoe and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2010.
In vitro delivery of anti-breast cancer agents directly via the mammary papilla (nipple).
International Journal of Pharmaceutics
387
(1-2)
, pp. 161-166.
10.1016/j.ijpharm.2009.12.021
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Zulfakar, Modh Hanif, Abdelouahab, Nassima and Heard, Christopher Martin ORCID: https://orcid.org/0000-0001-9703-9777
2010.
Enhanced topical delivery and ex vivo anti-inflammatory activity from a betamethasone dipropionate formulation containing fish oil.
Inflammation Research
59
(1)
, pp. 23-30.
10.1007/s00011-009-0065-z
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Lau, Wing Man ORCID: https://orcid.org/0000-0002-2998-6470, White, Alex William ORCID: https://orcid.org/0000-0002-1539-0158 and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2010.
Topical delivery of a naproxen-dithranol co-drug: in vitro skin penetration, permeation, and staining.
Pharmaceutical Research
27
(12)
, pp. 2734-2742.
10.1007/s11095-010-0274-8
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Samah, Nor Abu, Williams, Nicholas and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2010.
Nanogel particulates located within diffusion cell receptor phases following topical application demonstrates uptake into and migration across skin.
International Journal of Pharmaceutics
401
(1-2)
, pp. 72-78.
10.1016/j.ijpharm.2010.08.011
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Davison, Zoe, Nicholson, Robert Ian, Maillard, Jean-Yves ORCID: https://orcid.org/0000-0002-8617-9288, Denyer, Stephen Paul and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2009.
Control of microbial contamination of Franz diffusion cell receptor phase in the development of transcutaneous breast cancer therapeutics.
Letters in Applied Microbiology
49
(4)
, pp. 456-460.
10.1111/j.1472-765X.2009.02685.x
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Abdelouahab, Nassima and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2009.
A novel ex vivo skin model for the assessment of the potential transcutaneous anti-inflammatory effect of topically applied Harpagophytum procumbens extract.
International Journal of Pharmaceutics
376
(1-2)
, pp. 63-68.
10.1016/j.ijpharm.2009.04.017
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Davison, Zoe, Nicholson, Robert Ian, Maillard, Jean Yves ORCID: https://orcid.org/0000-0002-8617-9288, Denyer, Stephen Paul and Heard, Christopher Martin ORCID: https://orcid.org/0000-0001-9703-9777
2009.
Control of microbial contamination of Franz diffusion cell receptor phase in the development of transcutaneous breast cancer therapeutics.
Letters In Applied Microbiology
49
(4)
, pp. 456-460.
10.1111/j.1472-765X.2009.02685.x
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Morris, A. P., Brain, Keith Roger and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2009.
Skin permeation and ex vivo skin metabolism of O-acyl haloperidol ester prodrugs.
International Journal of Pharmaceutics
367
(1-2)
, pp. 44-50.
10.1016/j.ijpharm.2008.09.013
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Ong, C. M. Y. and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2009.
Permeation of quinine across sublingual mucosa, in vitro.
International Journal of Pharmaceutics
366
(1-2)
, pp. 58-64.
10.1016/j.ijpharm.2008.08.048
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Davison, Zoe, Dutkowski, Carol Mary, Gee, Julia Margaret Wendy ORCID: https://orcid.org/0000-0001-6483-2015, Nicholson, Robert Ian and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2008.
In vitro effects on MCF-7 breast cancer cells of signal transduction inhibitor/tamoxifen/eicosapentaenoic acid combinations and their simultaneous delivery across skin.
Pharmaceutical Research
25
(11)
, pp. 2516-2525.
10.1007/s11095-008-9665-5
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Elgorashi, Abubakr S., Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777, Niazy, Esmail M., Noureldin, Osman H. and Pugh, William John
2008.
Transdermal delivery enhancement of haloperidol from gel formulations by 1,8-cineole.
Journal of Pharmacy and Pharmacology
60
(6)
, pp. 689-692.
10.1211/jpp.60.6.0002
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Abdelouahab, Nassima and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2008.
Effect of the major glycosides of Harpagophytum procumbens (Devil's Claw) on epidermal cyclooxygenase-2 (COX-2) in vitro.
Journal of Natural Products
71
(5)
, pp. 746-749.
10.1021/np070204u
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Abdelouahab, Nassima and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2008.
Dermal and transcutaneous delivery of the major glycoside constituents of Harpagophytum procumbens (Devil's Claw) in vitro.
Planta Medica
74
(5)
, pp. 527-531.
10.1055/s-2008/1074500
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Abdulmajed, K. and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2008.
Topical delivery of retinyl ascorbate.
Skin Pharmacology and Physiology
21
(1)
, pp. 46-49.
10.1159/000111135
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|
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Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777 and Screen, C.
2008.
Probing the permeation enhancement of mefenamic acid by ethanol across full-thickness skin, heat-separated epidermal membrane and heat-separated dermal membrane.
International Journal of Pharmaceutics
349
(1-2)
, pp. 323-325.
10.1016/j.ijpharm.2007.08.006
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Lau, Wing Man ORCID: https://orcid.org/0000-0002-2998-6470, White, Alex William ORCID: https://orcid.org/0000-0002-1539-0158, Gallagher, S. J., Donaldson, M., McNaughton, G. and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2008.
Scope and limitations of the co-drug approach to topical drug delivery.
Current Pharmaceutical Design
14
(8)
, pp. 794-802.
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Morris, Andrew ORCID: https://orcid.org/0000-0002-6315-7553, Brain, Keith Roger and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2008.
Synthesis of haloperidol prodrugs and their hydrolysis by porcine liver esterase.
Drug Metabolism Letters
2
(4)
, pp. 275-279.
10.2174/187231208786734111
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Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777 and Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613
2007.
Probing the skin permeation of eicosapentaenoic acid and ketoprofen 2. Comparative depth profiling and metabolism of eicosapentaenoic acid.
European Journal of Pharmaceutics and Biopharmaceutics
67
(1)
, pp. 156-165.
10.1016/j.ejpb.2006.11.024
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Cole, Louise and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2007.
Skin permeation enhancement potential of aloe vera and a proposed mechanism of action based upon size exclusion and pull effect.
International Journal of Pharmaceutics
333
(1-2)
, pp. 10-16.
10.1016/j.ijpharm.2006.09.047
|
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Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Davison, Zoe and Heard, Christopher Martin ORCID: https://orcid.org/0000-0001-9703-9777
2007.
Probing the skin permeation of fish oil/EPA and ketoprofen-3. Effects on epidermal COX-2 and LOX.
Prostaglandins Leukotrienes & Essential Fatty Acids
76
(6)
, pp. 357-362.
10.1016/j.plefa.2007.05.002
|
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Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613 and Heard, Christopher Martin ORCID: https://orcid.org/0000-0001-9703-9777
2007.
Probing the skin permeation of eicosapentaenoic acid and ketoprofen - 2. Comparative depth profiling and metabolism of eicosapentaenoic acid.
European Journal of Pharmaceutics and Biopharmaceutics
67
(1)
, pp. 156-165.
10.1016/j.ejpb.2006.11.024
|
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Zulfakar, Modh Hanif, Edwards, M. and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2007.
Is there a role for topically delivered eicosapentaenoic acid in the treatment of psoriasis?
European Journal of Dermatology
17
(4)
, pp. 284-291.
10.1684/ejd.2007.0201
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Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777, Johnson, Sarah, Moss, Gary and Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613
2006.
In vitro transdermal delivery of caffeine, theobromine, theophylline and catechin from extract of Guarana, Paullinia Cupana.
International Journal of Pharmaceutics
317
(1)
, pp. 26-31.
10.1016/j.ijpharm.2006.02.042
|
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|
Richards, Helen, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Bowen, Jenna L. ORCID: https://orcid.org/0000-0003-1964-6832 and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2006.
In-vitro transcutaneous delivery of ketoprofen and polyunsaturated fatty acids from a pluronic lecithin organogel vehicle containing fish oil.
African Journal of Pharmacy and Pharmacology
58
(7)
, pp. 903-908.
10.1211/jpp.58.7.0004
|
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Bowen, Jenna L. ORCID: https://orcid.org/0000-0003-1964-6832 and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2006.
Film drying and complexation effects in the simultaneous skin permeation of ketoprofen and propylene glycol from simple gel formulations.
International Journal of Pharmaceutics
307
(2)
, pp. 251-257.
10.1016/j.ijpharm.2005.10.014
|
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Abdulmajed, Kasem, McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2006.
Topical delivery of retinyl ascorbate co-drug. 5. in vitro degradation studies.
Skin Pharmacology and Physiology
19
(5)
, pp. 248-258.
10.1159/000093980
|
|
|
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Abdulmajed, Karim, McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2005.
Topical delivery of retinyl ascorbate co-drug: 6. determination of toxic dose and antioxidant activity in cultured human epidermal keratinocytes.
Die Pharmazie - An International Journal of Pharmaceutical Sciences,
60
(10)
, pp. 794-795.
|
|
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Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777, Gallagher, Simon John, Congiatu, Costantino, Harwood, John L. ORCID: https://orcid.org/0000-0003-2377-2612, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X, Nemcova, Marta and Nouskova, Tereza
2005.
Preferential π–π complexation between tamoxifen and borage oil/γ linolenic acid: transcutaneous delivery and NMR spectral modulation.
International Journal of Pharmaceutics
302
(1-2)
, pp. 47-55.
10.1016/j.ijpharm.2005.06.013
|
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Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777, Abdulmajed, K and McCuigan, C
2005.
Topical delivery of retinyl ascorbate co-drug: 4. Comparative anti-oxidant activity towards DPPH.
Free Radical Research
39
(5)
, pp. 491-498.
10.1080/10715760500072263
|
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|
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Abdulmajed, Kasem, McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2005.
Topical delivery of retinyl ascorbate: 4. comparative anti-oxidant activity towards DPPH.
Free Radical Research
39
(5)
, pp. 491-498.
10.1080/10715760500072263
|
|
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Chilcott, R. P., Barai, N., Beezer, A. E., Brain, Sally Innis, Brown, M. B., Bunge, A. L., Burgess, S. E., Cross, S., Dalton, C. H., Dias, M., Farinha, A., Finnin, B. C., Gallagher, Simon John, Green, D. M., Gunt, H., Gwyther, R. L., Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777, Jarvis, C. A., Kamiyama, F., Kasting, G. B., Ley, E. E., Lim, S. T., Mcnaughton, Graham Stephen, Morris, A., Nazemi, Mohammed Husein, Pellett, M. A., Du Plessis, J., Quan, Y. S., Raghavan, S. L., Roberts, M., Romonchuk, W., Roper, C. S., Schenk, D., Simonsen, L., Simpson, A., Traversa, B. D., Trottet, L., Watkinson, A., Wilkinson, S. C., Williams, F. M., Yamamoto, A. and Hadgraft, J.
2005.
Inter- and intralaboratory variation of in vitro diffusion cell measurements: an international multicenter study using quasi-standardized methods and materials.
Journal of Pharmaceutical Sciences
94
(3)
, pp. 632-638.
10.1002/jps.20229
|
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Gallagher, S. J. and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2005.
Solvent content and macroviscosity effects on the in vitro transcutaneous delivery and skin distribution of ketoprofen from simple gel formulations.
Skin Pharmacology and Physiology
18
(4)
, pp. 186-194.
10.1159/000085864
|
|
|
|
Ho, Suzanna, Calder, Richard J., Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613 and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2004.
In-vitro transcutaneous delivery of tamoxifen and γ-linolenic acid from borage oil containing ethanol and 1,8-cineole.
Pharmacy and Pharmacology
56
(11)
, pp. 1357-1364.
10.1211/0022357044599
|
|
|
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Abdulmajed, K., Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777, McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X and Pugh, William John
2004.
Topical delivery of retinyl ascorbate co-drug - 2. Comparative skin tissue and keratin binding studies.
Skin Pharmacology and Physiology
17
(6)
, pp. 274-282.
10.1159/000081112
|
|
|
|
Batchelder, R. J., Calder, R. J., Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613 and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2004.
In vitro transdermal delivery of the major catechins and caffeine from extract of Camellia sinensis.
International Journal of Pharmaceutics
283
(1-2)
, pp. 45-51.
10.1016/j.ijpharm.2004.06.007
|
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|
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Abdulmajed, Kasem and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2004.
Topical delivery of retinyl ascorbate co-drug - 1. synthesis, penetration into and permeation across human skin.
International Journal of Pharmaceutics
280
(1-2)
, pp. 113-124.
10.1016/j.ijpharm.2004.05.008
|
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|
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Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777, Jarvis, Chris A and McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X
2004.
In vitro delivery of novel, highly potent anti-varicella zoster virus nucleoside analogues to their target site in the skin.
Pharmaceutical Research
21
(6)
, pp. 914-919.
10.1023/B:PHAM.0000029277.60760.43
|
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Karia, Clare, Harwood, John L. ORCID: https://orcid.org/0000-0003-2377-2612, Morris, Andrew and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2004.
Simultaneous permeation of tamoxifen and gamma linolenic acid across excised human skin. Further evidence of the permeation of solvated complexes.
International Journal of Pharmaceutics
271
(1-2)
, pp. 305-309.
10.1016/j.ijpharm.2003.11.017
|
|
|
|
Gallagher, Simon J., Trottet, Lionel and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2003.
Ketoprofen: release from, permeation across and rheology of simple gel formulations that simulate increasing dryness.
International Journal of Pharmaceutics
268
(1-2)
, pp. 37-45.
10.1016/j.ijpharm.2003.08.012
|
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Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777, Gallagher, Simon John, Harwood, John L. ORCID: https://orcid.org/0000-0003-2377-2612 and Maguire, Paula B.
2003.
The in vitro delivery of NSAIDS across skin was in proportion to the delivery of essential fatty acids in the vehicle - evidence that solutes permeate skin associated with their solvation cages?
International Journal of Pharmaceutics
261
(1-2)
, pp. 165-169.
10.1016/S0378-5173(03)00297-7
|
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|
Aboul-Enein, H. Y., El-Awady, M. I. and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2003.
Enantiomeric resolution of some 2-arylpropionic acids using L(-)-serine-impregnated silica as stationary phase by thin layer chromatography.
Journal of Pharmaceutical and Biomedical Analysis
32
(4-5)
, pp. 1055-1059.
10.1016/S0731-7085(03)00208-5
|
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|
|
Jarvis, C. A., Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777 and McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X
2003.
Targeted dermal delivery of highly potent anti-varicella zoster virus nucleoside analogues from saturated solutions and ethanolic oil-in-water creams.
Journal of drug targeting
11
(7)
, pp. 433-441.
10.1080/1061186042000201990
|
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Aboul-Enein, Hassan Y., El-Awady, Mahmoud I. and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2003.
Thin layer chromatographic resolution of some 2-arylpropionic acid enantiomers using L-(-)-serine, L-(-)-threonine and a mixture of L-(-)-serine and L-(-)threonine-impregnated silica gel as stationary phases.
Biomedical Chromatography
17
(5)
, pp. 325-334.
10.1002/bmc.245
|
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|
Gallagher, S. J., Trottet, L., Carter, T. P. and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2003.
Effects of membrane type and liquid/liquid phase boundary on in vitro release of ketoprofen from gel formulations.
Journal of drug targeting
11
(6)
, pp. 373-379.
10.1080/10611860310001636890
|
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Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777, Monk, B and Modley, A. J.
2003.
Binding of primaquine to epidermal membranes and keratin.
International Journal of Pharmaceutics
257
(1-2)
, pp. 237-244.
10.1016/S0378-5173(03)00140-6
|
|
|
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Jarvis, Chris, McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2003.
Penetration of highly active anti-VZV nucleoside analogues into and through full-thickness skin.
Antiviral Research
57
(3)
, A68-A68.
|
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Banning, Thomas P. and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2002.
Binding of doxycycline to keratin, melanin and human epidermal tissue.
International Journal of Pharmaceutics
235
(1-2)
, pp. 219-227.
10.1016/S0378-5173(01)00988-7
|
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|
Chedgzoy, P., Winckle, Gareth and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2002.
Triclosan: release from transdermal adhesive formulations and in vitro permeation across human epidermal membranes.
International Journal of Pharmaceutics
235
(1-2)
, pp. 229-236.
10.1016/S0378-5173(01)00992-9
|
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|
|
Aboul-Enein, H. Y., El-Awady, M. I. and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2002.
Direct enantiomeric resolution of some cardiovascular agents using synthetic polymers imprinted with (-)-S-timolol as chiral stationary phase by thin layer chromatography.
Die Pharmazie - An International Journal of Pharmaceutical Sciences,
57
(3)
, pp. 169-171.
|
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Allender, Christopher John, Richardson, C., Woodhouse, B., Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777 and Brain, Keith Roger
2000.
Pharmaceutical applications for molecularly imprinted polymers.
International Journal of Pharmaceutics
195
(1-2)
, pp. 39-43.
10.1016/S0378-5173(99)00355-5
|
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|
|
Aboul-Enein, H. Y., El-Awady, M. I. and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2000.
Enantiomeric separation of aminoglutethimide, acetyl aminoglutethimide, and dansyl aminoglutethimide by tlc with beta-cyclodextrin and derivatives as mobile phase additives.
Journal of Liquid Chromatography and Related Technologies
23
(17)
, pp. 2715-2726.
10.1081/JLC-100101829
|
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Aboul-Enein, H. Y., El-Awady, M. I., Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777 and Nicholls, P. J.
1999.
Application of thin-layer chromatography in enantiomeric chiral analysis - an overview.
Biomedical Chromatography
13
(8)
, pp. 531-537.
10.1002/(SICI)1099-0801(199912)13:8<531::AID-BMC921>3.0.CO;2-Q
|
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Perkins, Nia C. and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
1999.
In vitro dermal and transdermal delivery of doxycycline from ethanol/migliol 840 vehicles.
International Journal of Pharmaceutics
190
(2)
, pp. 155-164.
10.1016/S0378-5173(99)00240-9
|
|
|
|
Jeans, C. W. and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
1999.
A therapeutic dose of primaquine can be delivered across excised human skin from simple transdermal patches.
International Journal of Pharmaceutics
189
(1)
, pp. 1-6.
10.1016/S0378-5173(99)00215-X
|
|
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|
Suedee, R., Brain, Keith Roger and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
1997.
Enantioselective retardation of rac-propranolol from matrices containing cellulose derivatives.
Chirality -New York-
9
(3)
, pp. 307-312.
10.1002/(SICI)1520-636X(1997)9:3<307::AID-CHIR18>3.0.CO;2-R
|
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|
Suedee, R. and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
1997.
Direct resolution of propranolol and bupranolol by thin-layer chromatography using cellulose derivatives as stationary phase.
Chirality -New York-
9
(2)
, pp. 139-144.
10.1002/(SICI)1520-636X(1997)9:2<139::AID-CHIR11>3.0.CO;2-O
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Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777 and Suedee, R.
1996.
Stereoselective adsorption and trans-membrane transfer of propranolol enantiomers using cellulose derivatives.
International Journal of Pharmaceutics
139
(1-2)
, pp. 15-23.
10.1016/0378-5173(96)04564-4
|
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Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777 and Hadgraft, Jonathan
1996.
Ion-pairing interactions between 99mTc-based myocardial imaging agents and oleic acid.
Pharmaceutical Research
13
(2)
, pp. 316-323.
|
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Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777 and Brain, Keith Roger
1995.
Does solute stereochemistry influence percutaneous penetration?
Chirality -New York-
7
(4)
, pp. 305-309.
|
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Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777, Watkinson, A. C., Brain, Keith Roger and Hadgraft, J.
1993.
Invitro skin penetration of propranolol enantiomers.
International Journal of Pharmaceutics
90
(3)
, R5-R8.
10.1016/0378-5173(93)90202-Q
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