Hardwicke, Joseph, Hart, Jeff, Bell, Andrea, Duncan, Ruth, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 and Moseley, Ryan ORCID: https://orcid.org/0000-0002-2812-6735 2011. The effect of dextrin-rhEGF on the healing of full-thickness, excisional wounds in the (db/db) diabetic mouse. Journal of Controlled Release 152 (3) , pp. 411-417. 10.1016/j.jconrel.2011.03.016 |
Izzo, Lorella, Griffiths, Peter Charles, Nilmini, Renuka, King, Stephen M., Wallom, Kerri-Lee, Ferguson, Elaine Lesley ORCID: https://orcid.org/0000-0002-0125-0234 and Duncan, Ruth 2011. Impact of polymer tacticity on the physico-chemical behaviour of polymers proposed as therapeutics. International Journal of Pharmaceutics 408 (1-2) , pp. 213-222. 10.1016/j.ijpharm.2011.02.003 |
Deacon, Samuel P. E., Apostolovic, Bojana, Carbajo, Rodrigo J., Schott, Anne-Kathrin, Beck, Konrad ORCID: https://orcid.org/0000-0001-5098-9484, Vicent, Maria J., Pineda-Lucena, Antonio, Klok, Harm-Anton and Duncan, Ruth 2011. Polymer coiled-coil conjugates: potential for development as a new class of therapeutic "molecular switch". Biomacromolecules 12 (1) , pp. 19-27. 10.1021/bm100843e |
Griffiths, Peter Charles, Nilmini, Renuka, Carter, Emma ORCID: https://orcid.org/0000-0001-6691-2377, Dodds, Patrick ORCID: https://orcid.org/0000-0001-9326-765X, Murphy, Damien Martin ORCID: https://orcid.org/0000-0002-5941-4879, Khayat, Zeena, Lattanzio, Ettore, Ferruti, Paolo, Heenan, Richard K., King, Stephen M. and Duncan, Ruth 2010. Interaction of an endosomolytic polyamidoamine ISA23 with vesicles mimicking intracellular membranes: A SANS/EPR study. Macromolecular Bioscience 10 (8) , pp. 963-973. 10.1002/mabi.201000040 |
Hardwicke, Joseph, Moseley, Ryan ORCID: https://orcid.org/0000-0002-2812-6735, Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Harding, Keith Gordon, Duncan, Ruth and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2010. Bioresponsive dextrin-rhEGF conjugates: in vitro evaluation in models relevant to its proposed use as a treatment for chronic wounds. Molecular Pharmaceutics 7 (3) , pp. 699-707. 10.1021/mp9002656 |
Ferguson, Elaine Lesley ORCID: https://orcid.org/0000-0002-0125-0234, Richardson, Simon C. W. and Duncan, Ruth 2010. Studies on the mechanism of action of dextrin-phospholipase A2 and its suitability for use in combination therapy. Molecular Pharmaceutics 7 (2) , pp. 510-521. 10.1021/mp900232a |
Ferguson, Elaine Lesley ORCID: https://orcid.org/0000-0002-0125-0234 and Duncan, Ruth 2009. Dextrin-phospholipase A2: Synthesis and evaluation as a bioresponsive anticancer conjugate. Biomacromolecules 10 (6) , pp. 1358-1364. 10.1021/bm8013022 |
Treetharnmathurot, Benjaporn, Dieudonné, L., Ferguson, Elaine ORCID: https://orcid.org/0000-0002-0125-0234, Schmaljohann, Dirk, Duncan, Ruth and Wiwattanapatapee, R. 2009. Dextrin-trypsin and ST-HPMA-trypsin conjugates: Enzyme activity, autolysis and thermal stability. International Journal of Pharmaceutics 373 (1-2) , pp. 68-76. 10.1016/j.ijpharm.2009.02.008 |
Vicent, M. J., Ringsdorf, H. and Duncan, Ruth 2009. Polymer therapeutics: Clinical applications and challenges for development. Advanced Drug Delivery Reviews 61 (13) , pp. 1117-1120. 10.1016/j.addr.2009.08.001 |
Hardwicke, Joseph, Ferguson, Elaine Lesley ORCID: https://orcid.org/0000-0002-0125-0234, Moseley, Ryan ORCID: https://orcid.org/0000-0002-2812-6735, Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 and Duncan, Ruth 2008. Dextrin-rhEGF conjugates as bioresponsive nanomedicines for wound repair. Journal of Controlled Release 130 (3) , pp. 275-283. 10.1016/j.jconrel.2008.07.023 |
Richardson, Simon C. W., Wallom, Kerri-Lee, Ferguson, Elaine Lesley ORCID: https://orcid.org/0000-0002-0125-0234, Deacon, Simon P. E., Davies, Matthew W., Powell, Alison J., Piper, Robert C. and Duncan, Ruth 2008. The use of fluorescence microscopy to define polymer localisation to the late endocytic compartments in cells that are targets for drug delivery. Journal of Controlled Release 127 (1) , pp. 1-11. 10.1016/j.jconrel.2007.12.015 |
Paul, Alison ORCID: https://orcid.org/0000-0002-7653-9964, Vicent, Maria Jesus and Duncan, Ruth 2007. Using Small-Angle Neutron Scattering to Study the Solution Conformation of N-(2-Hydroxypropyl)methacrylamide Copolymer-Doxorubicin Conjugates. Biomacromolecules 8 (5) , pp. 1573-1579. 10.1021/bm060925s |
Griffiths, Peter Charles, Khayat, Zeena, Tse, Stephanie, Heenan, Richard K., King, Stephen M. and Duncan, Ruth 2007. Studies on the Mechanism of Interaction of a Bioresponsive Endosomolytic Polyamidoamine with Interfaces. 1. Micelles as Model Surfaces. Biomacromolecules 8 (3) , pp. 1004-1012. 10.1021/bm060930w |
Greco, F., Vicent, M. J., Gee, S., Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905, Gee, Julia Margaret Wendy ORCID: https://orcid.org/0000-0001-6483-2015, Nicholson, Robert Ian and Duncan, Ruth 2007. Investigating the mechanism of enhanced cytotoxicity of HPMA copolymer-Dox-AGM in breast cancer cells. Journal of Controlled Release 117 (1) , pp. 28-39. 10.1016/j.jconrel.2006.10.012 |
Manunta, M., Izzo, L., Duncan, Ruth and Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2007. Establishment of subcellular fractionation techniques to monitor the intracellular fate of polymer therapeutics II. Identification of endosomal and lysosomal compartments in HepG2 cells combining single-step subcellular fractionation with fluorescent imaging. Journal of Drug Targeting 15 (1) , pp. 37-50. 10.1080/10611860601010330 |
Seib, F. P., Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 and Duncan, Ruth 2007. Comparison of the endocytic properties of linear and branched PEIs, and cationic PAMAM dendrimers in B16f10 melanoma cells. Journal of Controlled Release 117 (3) , pp. 291-300. 10.1016/j.jconrel.2006.10.020 |
Berna, Manuela, Dalzoppo, Daniele, Pasut, Gianfranco, Manunta, Maria, Izzo, Lorella, Jones, Arwyn ORCID: https://orcid.org/0000-0003-2781-8905, Duncan, Ruth and Veronese, Francesco M. 2006. Novel monodisperse PEG-dendrons as new tools for targeted drug delivery: Synthesis, characterisation and cellular uptake. Biomacromolecules 7 (1) , pp. 146-153. 10.1021/bm050480s |
Seib, Friedrich Philipp, Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 and Duncan, Ruth 2006. Establishment of subcellular fractionation techniques to monitor the intracellular fate of polymer therapeutics I. Differential centrifugation fractionation B16F10 cells and use to study the intracellular fate of HPMA copolymer-doxorubicin. Journal of drug targeting 14 (6) , pp. 375-390. 10.1080/10611860600833955 |
Duncan, Ruth, Greco, F, Nicholson, RI and Vicent, MJ 2005. Polymer therapeutics designed for a combination therapy of hormone-dependent cancer. Angewandte Chemie International Edition 44 (26) , pp. 4061-4066. 10.1002/anie.200462960 |
Shaunak, Sunil, Thomas, Sharyn, Gianasi, Elisabetta, Godwin, Antony, Jones, Emma, Teo, Ian, Mireskandari, Kamiar, Luthert, Philip, Duncan, Ruth, Patterson, Steve, Khaw, Peng and Brocchini, Steve 2004. Polyvalent dendrimer glucosamine conjugates prevent scar tissue formation. Nature Biotechnology 22 (8) , pp. 977-984. 10.1038/nbt995 |
Duncan, Ruth, Davies, JW, Hailu, H and Satchi-Fainaro, R 2003. PDEPT: Polymer directed enzyme prodrug therapy: 2. HPMA copolymer-β-lactamase and HPMA copolymer-C-Dox as a model combination. Bioconjugate Chemistry 14 (4) , pp. 797-804. 10.1021/bc020091k |
Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905, Gumbleton, Mark ORCID: https://orcid.org/0000-0002-7386-311X and Duncan, Ruth 2003. Understanding endocytic pathways and intracellular trafficking: a prerequisite for effective design of advanced drug delivery systems. Advanced Drug Delivery Reviews 55 (11) , pp. 1353-1367. 10.1016/j.addr.2003.07.002 |