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Number of items: 33.

Wootton, Hannah S., Berry, Sian S., Ferguson, Elaine L. ORCID: https://orcid.org/0000-0002-0125-0234, Mahon, Clare S. and Miller, Gavin J. 2024. Adaptable synthesis of chondroitin sulfate disaccharide subtypes preprogrammed for regiospecific O-sulfation. European Journal of Organic Chemistry 27 (40) , e202400587. 10.1002/ejoc.202400587
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Rizzo, Siân, Varache, Mathieu ORCID: https://orcid.org/0000-0001-7166-2253, Sayers, Edward J. ORCID: https://orcid.org/0000-0002-2621-1119, Jones, Arwyn T. ORCID: https://orcid.org/0000-0003-2781-8905, Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976, Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 and Ferguson, Elaine L. ORCID: https://orcid.org/0000-0002-0125-0234 2024. Modification of the antibiotic, colistin, with dextrin causes enhanced cytotoxicity and triggers apoptosis in myeloid leukemia. International Journal of Nanomedicine 19 , pp. 5419-5437. 10.2147/IJN.S449185
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Wootton, Hannah S., Berry, Sian S., Ferguson, Elaine L. ORCID: https://orcid.org/0000-0002-0125-0234, Mahon, Clare S. and Miller, Gavin J. 2024. Adaptable synthesis of chondroitin sulfate disaccharide subtypes preprogrammed for regiospecific O-sulfation. Organic Chemistry 10.26434/chemrxiv-2024-nlm1k
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Varache, Mathieu ORCID: https://orcid.org/0000-0001-7166-2253, Rizzo, Siân, Sayers, Edward J. ORCID: https://orcid.org/0000-0002-2621-1119, Newbury, Lucy, Mason, Anna, Liao, Chia-Te, Chiron, Emilie, Bourdiec, Nathan, Jones, Adam, Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342, Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421, Jones, Arwyn T. ORCID: https://orcid.org/0000-0003-2781-8905, Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 and Ferguson, Elaine L. ORCID: https://orcid.org/0000-0002-0125-0234 2024. Dextrin conjugation to colistin inhibits its toxicity, cellular uptake and acute kidney injury in vivo. RSC Pharmaceutics 1 , pp. 68-79. 10.1039/D3PM00014A
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Sharma, Priyasha, Richards, Charlotte ORCID: https://orcid.org/0000-0002-4624-1155, Adams, Jennifer, Powell, Lydia ORCID: https://orcid.org/0000-0002-8641-0160, Ferguson, Elaine ORCID: https://orcid.org/0000-0002-0125-0234, Coutinho, Grace, Hallett, Thomas, Kulasekaran, Anuradha, Thomas, David ORCID: https://orcid.org/0000-0001-7319-5820 and Hill, Katja ORCID: https://orcid.org/0000-0002-8590-0117 2023. In vitro antibiofilm activity of hexylresorcinol lozenges against oropharyngeal pathogens. Presented at: 2023 ERS International Congress, Milan, Italy, 9-13 September 2023. European Respiratory Journal. European Respiratory Society, 10.1183/13993003.congress-2023.PA603

Stokniene, Joana, Varache, Mathieu ORCID: https://orcid.org/0000-0001-7166-2253, Rye, Philip D, Hill, Katja E ORCID: https://orcid.org/0000-0002-8590-0117, Thomas, David W ORCID: https://orcid.org/0000-0001-7319-5820 and Ferguson, Elaine L ORCID: https://orcid.org/0000-0002-0125-0234 2022. Alginate oligosaccharides enhance diffusion and activity of colistin in a mucin-rich environment. Scientific Reports 12 , 4986. 10.1038/s41598-022-08927-1
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Chiron, Emilie, Varache, Mathieu ORCID: https://orcid.org/0000-0001-7166-2253, Stokniene, Joana, Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 and Ferguson, Elaine L. ORCID: https://orcid.org/0000-0002-0125-0234 2021. A physicochemical assessment of the thermal stability of dextrin–colistin conjugates. Scientific Reports 11 , 10600. 10.1038/s41598-021-89946-2
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Stokniene, Joana, Powell, Lydia C. ORCID: https://orcid.org/0000-0002-8641-0160, Aarstad, Olav A., Aachmann, Finn L., Rye, Philip D., Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117, Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 and Ferguson, Elaine L. ORCID: https://orcid.org/0000-0002-0125-0234 2020. Bi-functional alginate oligosaccharide–polymyxin conjugates for improved treatment of multidrug-resistant gram-negative bacterial infections. Pharmaceutics 12 (11) , 1080. 10.3390/pharmaceutics12111080
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Ferguson, Elaine ORCID: https://orcid.org/0000-0002-0125-0234, Varache, Mathieu ORCID: https://orcid.org/0000-0001-7166-2253, Stokniene, Joana and Thomas, David 2019. Polysaccharides for protein and peptide conjugation. Pasut, Gianfranco and Zalipsky, Samuel, eds. Polymer-Protein Conjugates: From Pegylation and Beyond, Elsevier, pp. 421-453. (10.1016/B978-0-444-64081-9.00019-X)

Varache, Mathieu ORCID: https://orcid.org/0000-0001-7166-2253, Powell, Lydia C. ORCID: https://orcid.org/0000-0002-8641-0160, Aarstad, Olav A., Williams, Thomas L., Wenzel, Margot N. ORCID: https://orcid.org/0000-0001-6411-1816, Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 and Ferguson, Elaine L. ORCID: https://orcid.org/0000-0002-0125-0234 2019. Polymer masked-unmasked protein therapy: Identification of the active species after amylase-activation of dextrin-colistin conjugates. Molecular Pharmaceutics 16 (7) , pp. 3199-3207. 10.1021/acs.molpharmaceut.9b00393
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Ferguson, Elaine L ORCID: https://orcid.org/0000-0002-0125-0234, Naseer, Sameza, Powell, Lydia C ORCID: https://orcid.org/0000-0002-8641-0160, Hardwicke, Joseph, Young, Fraser I ORCID: https://orcid.org/0000-0003-0779-3835, Zhu, Bangfu, Liu, Qian, Song, Bing ORCID: https://orcid.org/0000-0001-9356-2333 and Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 2018. Controlled release of Dextrin-conjugated growth factors to support growth and differentation of neural stem cells. Stem Cell Research 33 , pp. 69-78. 10.1016/j.scr.2018.10.008
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Powell, Lydia C. ORCID: https://orcid.org/0000-0002-8641-0160, Pritchard, Manon F. ORCID: https://orcid.org/0000-0002-5135-4744, Ferguson, Elaine L. ORCID: https://orcid.org/0000-0002-0125-0234, Powell, Kate A. ORCID: https://orcid.org/0000-0002-8641-0160, Patel, Shree U., Rye, Phil D., Sakellakou, Stavroula-Melina, Buurma, Niklaas J. ORCID: https://orcid.org/0000-0003-0260-5057, Brilliant, Charles D., Copping, Jack M., Menzies, Georgina E. ORCID: https://orcid.org/0000-0002-6600-6507, Lewis, Paul D., Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117 and Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 2018. Targeted disruption of the extracellular polymeric network of pseudomonas aeruginosa biofilms by alginate oligosaccharides. npj Biofilms and Microbiomes 4 , 13. 10.1038/s41522-018-0056-3
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Scomparin, Anna, Florindo, Helena F., Tiram, Galia, Ferguson, Elaine L. ORCID: https://orcid.org/0000-0002-0125-0234 and Satchi-Fainaro, Ronit 2017. Two-step polymer- and liposome- enzyme prodrug therapies for cancer: PDEPT and PELT concepts and future perspectives. Advanced Drug Delivery Reviews 118 , pp. 52-64. 10.1016/j.addr.2017.09.011
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Ferguson, Elaine L. ORCID: https://orcid.org/0000-0002-0125-0234, Scomparin, Anna, Hailu, Hanna and Satchi-Fainaro, Ronit 2017. HPMA copolymer-phospholipase C and dextrin-phospholipase A2 as model triggers for polymer enzyme liposome therapy (PELT). Journal of drug targeting 25 (9-10) , pp. 818-828. 10.1080/1061186X.2017.1358726
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Pritchard, Manon F. ORCID: https://orcid.org/0000-0002-5135-4744, Powell, Lydia C. ORCID: https://orcid.org/0000-0002-8641-0160, Khan, Saira, Griffiths, Peter C., Mansour, Omar T., Schweins, Ralf, Beck, Konrad ORCID: https://orcid.org/0000-0001-5098-9484, Buurma, Niklaas J. ORCID: https://orcid.org/0000-0003-0260-5057, Dempsey, Christopher E., Wright, Chris J., Rye, Philip D., Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117, Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 and Ferguson, Elaine L. ORCID: https://orcid.org/0000-0002-0125-0234 2017. The antimicrobial effects of the alginate oligomer OligoG CF-5/20 are independent of direct bacterial cell membrane disruption. Scientific Reports 7 , 44731. 10.1038/srep44731
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Roberts, Jessica L., Cattoz, Beatrice, Schweins, Ralf, Beck, Konrad ORCID: https://orcid.org/0000-0001-5098-9484, Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820, Griffiths, Peter C. and Ferguson, Elaine L. ORCID: https://orcid.org/0000-0002-0125-0234 2016. In vitro evaluation of the interaction of dextrin-colistin conjugates with bacterial lipopolysaccharide. Journal of Medicinal Chemistry 59 (2) , pp. 647-654. 10.1021/acs.jmedchem.5b01521
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Azzopardi, Ernest A. ORCID: https://orcid.org/0000-0002-4511-0954, Ferguson, Elaine L. ORCID: https://orcid.org/0000-0002-0125-0234 and Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 2015. Development and validation of an in vitro pharmacokinetic/pharmacodynamic model to test the antibacterial efficacy of antibiotic polymer conjugates. Antimicrobial Agents and Chemotherapy 59 (4) , pp. 1837-1843. 10.1128/AAC.03708-14

Ferguson, Elaine L. ORCID: https://orcid.org/0000-0002-0125-0234, Azzopardi, Ernest ORCID: https://orcid.org/0000-0002-4511-0954, Roberts, Jessica L., Walsh, Timothy R. ORCID: https://orcid.org/0000-0003-4315-4096 and Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 2014. Dextrin-Colistin conjugates as a model bioresponsive treatment for multidrug resistant bacterial infections. Molecular Pharmaceutics 11 (12) , pp. 4437-4447. 10.1021/mp500584u
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Azzopardi, Ernest A. ORCID: https://orcid.org/0000-0002-4511-0954, Ferguson, Elaine Lesley ORCID: https://orcid.org/0000-0002-0125-0234 and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2014. A novel class of bioreponsive nanomedicines for localised reinstatement of bioactivity and specific targeting [Abstract]. The Lancet 383 , S9. 10.1016/S0140-6736(14)60272-5

Azzopardi, Ernest A. ORCID: https://orcid.org/0000-0002-4511-0954, Ferguson, Elaine Lesley ORCID: https://orcid.org/0000-0002-0125-0234 and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2013. Colistin past and future: A bibliographic analysis. Journal of Critical Care 28 (2) , 219.e13-219.e19. 10.1016/j.jcrc.2012.04.008

Azzopardi, Ernest A. ORCID: https://orcid.org/0000-0002-4511-0954, Camilleri, Liberato, Moseley, Ryan ORCID: https://orcid.org/0000-0002-2812-6735, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 and Ferguson, Elaine Lesley ORCID: https://orcid.org/0000-0002-0125-0234 2013. Statistical characterization of succinoylated dextrin degradation behavior in human α-amylase. Journal of Carbohydrate Chemistry 32 (7) , pp. 438-449. 10.1080/07328303.2013.831434

Naderi, Naghmeh, Madani, Seyed Y., Ferguson, Elaine Lesley ORCID: https://orcid.org/0000-0002-0125-0234, Mosahebi, Afshin and Seifalian, Alexander M. 2013. Carbon nanotubes in the diagnosis and treatment of malignant melanoma. Anti-Cancer Agents in Medicinal Chemistry 13 (1) , pp. 171-185. 10.2174/1871520611307010171

Azzopardi, Ernest A. ORCID: https://orcid.org/0000-0002-4511-0954, Ferguson, Elaine Lesley ORCID: https://orcid.org/0000-0002-0125-0234 and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2013. The enhanced permeability retention effect: a new paradigm for drug targeting in infection. Journal of Antimicrobial Chemotherapy 68 (2) , pp. 257-274. 10.1093/jac/dks379

Ferguson, Elaine Lesley ORCID: https://orcid.org/0000-0002-0125-0234, Roberts, Jessica Louise, Moseley, Ryan ORCID: https://orcid.org/0000-0002-2812-6735, Griffiths, Peter Charles and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2011. Evaluation of the physical and biological properties of hyaluronan and hyaluronan fragments. International Journal of Pharmaceutics 420 (1) , pp. 84-92. 10.1016/j.ijpharm.2011.08.031

Izzo, Lorella, Griffiths, Peter Charles, Nilmini, Renuka, King, Stephen M., Wallom, Kerri-Lee, Ferguson, Elaine Lesley ORCID: https://orcid.org/0000-0002-0125-0234 and Duncan, Ruth 2011. Impact of polymer tacticity on the physico-chemical behaviour of polymers proposed as therapeutics. International Journal of Pharmaceutics 408 (1-2) , pp. 213-222. 10.1016/j.ijpharm.2011.02.003

Ferguson, Elaine Lesley ORCID: https://orcid.org/0000-0002-0125-0234, Alshame, Alshame Mohamed J. and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2010. Evaluation of hyaluronic acid-protein conjugates for polymer masked-unmasked protein therapy. International Journal of Pharmaceutics 402 (1-2) , pp. 95-102. 10.1016/j.ijpharm.2010.09.029

Ferguson, Elaine Lesley ORCID: https://orcid.org/0000-0002-0125-0234, Richardson, Simon C. W. and Duncan, Ruth 2010. Studies on the mechanism of action of dextrin-phospholipase A2 and its suitability for use in combination therapy. Molecular Pharmaceutics 7 (2) , pp. 510-521. 10.1021/mp900232a

Ferguson, Elaine Lesley ORCID: https://orcid.org/0000-0002-0125-0234, De Luca, Edoardo, Heenan, Richard K., King, Stephen M. and Griffiths, Peter Charles 2010. Time-Resolved Small-Angle Neutron Scattering as a Tool for Studying Controlled Release from Liposomes using Polymer-Enzyme Conjugates. Macromolecular Rapid Communications 31 (19) , pp. 1685-1690. 10.1002/marc.201000241
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Ferguson, Elaine Lesley ORCID: https://orcid.org/0000-0002-0125-0234 and Duncan, Ruth 2009. Dextrin-phospholipase A2: Synthesis and evaluation as a bioresponsive anticancer conjugate. Biomacromolecules 10 (6) , pp. 1358-1364. 10.1021/bm8013022

Treetharnmathurot, Benjaporn, Dieudonné, L., Ferguson, Elaine ORCID: https://orcid.org/0000-0002-0125-0234, Schmaljohann, Dirk, Duncan, Ruth and Wiwattanapatapee, R. 2009. Dextrin-trypsin and ST-HPMA-trypsin conjugates: Enzyme activity, autolysis and thermal stability. International Journal of Pharmaceutics 373 (1-2) , pp. 68-76. 10.1016/j.ijpharm.2009.02.008

Hardwicke, Joseph, Ferguson, Elaine Lesley ORCID: https://orcid.org/0000-0002-0125-0234, Moseley, Ryan ORCID: https://orcid.org/0000-0002-2812-6735, Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 and Duncan, Ruth 2008. Dextrin-rhEGF conjugates as bioresponsive nanomedicines for wound repair. Journal of Controlled Release 130 (3) , pp. 275-283. 10.1016/j.jconrel.2008.07.023

Richardson, Simon C. W., Wallom, Kerri-Lee, Ferguson, Elaine Lesley ORCID: https://orcid.org/0000-0002-0125-0234, Deacon, Simon P. E., Davies, Matthew W., Powell, Alison J., Piper, Robert C. and Duncan, Ruth 2008. The use of fluorescence microscopy to define polymer localisation to the late endocytic compartments in cells that are targets for drug delivery. Journal of Controlled Release 127 (1) , pp. 1-11. 10.1016/j.jconrel.2007.12.015

Ferguson, Elaine Lesley ORCID: https://orcid.org/0000-0002-0125-0234 2008. Bioresponsive polymer-phospholipase A2 conjugates as novel anti-cancer agents. PhD Thesis, Cardiff University.
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