Browse by Current Cardiff authors

Sharma, Priyanka, Richards, Charlotte ORCID: https://orcid.org/0000-0002-4624-1155, Adams, Jennifer Y. M., Bentley, Kirsten ORCID: https://orcid.org/0000-0002-6619-2098, Razzak, Aamir, Claydon, Nicholas ORCID: https://orcid.org/0000-0002-4151-1515, Hallett, Thomas, Coutinho, Graca, Kulasekaran, Anuradha, Powell, Lydia C., Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182, Ferguson, Elaine L. ORCID: https://orcid.org/0000-0002-0125-0234, Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 and Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117 2025. The pharmacokinetics of hexylresorcinol-containing lozenges and their antimicrobial efficacy against oral and respiratory microorganisms. Journal of Oral Microbiology 17 (1) , 2525229. 10.1080/20002297.2025.2525229

Khubrani, Yahia H., Thomas, David ORCID: https://orcid.org/0000-0001-7319-5820, Slator, Paddy ORCID: https://orcid.org/0000-0001-6967-989X, White, Richard D. and Farnell, Damian J.J. ORCID: https://orcid.org/0000-0003-0662-1927 2024. Detection of periodontal bone loss and periodontitis from 2D dental radiographs via machine learning and deep learning: Systematic Review employing APPRAISE-AI and meta-analysis. Dentomaxillofacial Radiology , twae070. 10.1093/dmfr/twae070

Rizzo, Siân, Varache, Mathieu ORCID: https://orcid.org/0000-0001-7166-2253, Sayers, Edward J. ORCID: https://orcid.org/0000-0002-2621-1119, Jones, Arwyn T. ORCID: https://orcid.org/0000-0003-2781-8905, Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976, Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 and Ferguson, Elaine L. ORCID: https://orcid.org/0000-0002-0125-0234 2024. Modification of the antibiotic, colistin, with dextrin causes enhanced cytotoxicity and triggers apoptosis in myeloid leukemia. International Journal of Nanomedicine 19 , pp. 5419-5437. 10.2147/IJN.S449185

Varache, Mathieu ORCID: https://orcid.org/0000-0001-7166-2253, Rizzo, Siân, Sayers, Edward J. ORCID: https://orcid.org/0000-0002-2621-1119, Newbury, Lucy, Mason, Anna, Liao, Chia-Te, Chiron, Emilie, Bourdiec, Nathan, Jones, Adam, Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342, Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421, Jones, Arwyn T. ORCID: https://orcid.org/0000-0003-2781-8905, Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 and Ferguson, Elaine L. ORCID: https://orcid.org/0000-0002-0125-0234 2024. Dextrin conjugation to colistin inhibits its toxicity, cellular uptake and acute kidney injury in vivo. RSC Pharmaceutics 1 , pp. 68-79. 10.1039/D3PM00014A

Sharma, Priyasha, Richards, Charlotte ORCID: https://orcid.org/0000-0002-4624-1155, Adams, Jennifer, Powell, Lydia ORCID: https://orcid.org/0000-0002-8641-0160, Ferguson, Elaine ORCID: https://orcid.org/0000-0002-0125-0234, Coutinho, Grace, Hallett, Thomas, Kulasekaran, Anuradha, Thomas, David ORCID: https://orcid.org/0000-0001-7319-5820 and Hill, Katja ORCID: https://orcid.org/0000-0002-8590-0117 2023. In vitro antibiofilm activity of hexylresorcinol lozenges against oropharyngeal pathogens. Presented at: 2023 ERS International Congress, Milan, Italy, 9-13 September 2023. European Respiratory Journal. European Respiratory Society, 10.1183/13993003.congress-2023.PA603

Pritchard, Manon F. ORCID: https://orcid.org/0000-0002-5135-4744, Powell, Lydia C. ORCID: https://orcid.org/0000-0002-8641-0160, Adams, Jennifer Y.M., Menzies, Georgina ORCID: https://orcid.org/0000-0002-6600-6507, Khan, Saira, Tondervik, Anne, Sletta, Havard, Olav, Aarstad, Skjåk-Bræk, Gudmund, McKenna, Stephen, Buurma, Niklaas J. ORCID: https://orcid.org/0000-0003-0260-5057, Farnell, Damian J.J. ORCID: https://orcid.org/0000-0003-0662-1927, Rye, Philip D., Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117 and Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 2023. Structure–activity relationships of low molecular weight alginate oligosaccharide therapy against Pseudomonas aeruginosa. Biomolecules 13 (9) , 1366. 10.3390/biom13091366

Xue, Wenya, Pritchard, Manon F. ORCID: https://orcid.org/0000-0002-5135-4744, Khan, Saira, Powell, Lydia C., Stokniene, Joana, Wu, Jingxiang, Claydon, Nicholas ORCID: https://orcid.org/0000-0002-4151-1515, Reddell, Paul, Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 and Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117 2023. Defining in vitro topical antimicrobial and antibiofilm activity of epoxy-tigliane structures against oral pathogens. Journal of Oral Microbiology 15 (1) , 2241326. 10.1080/20002297.2023.2241326

Lohana, Parkash, Suryaprawira, Albert, Woods, Emma L., Dally, Jordanna, Gait-Carr, Edward, Alaidaroos, Nadia Y.A., Heard, Charles M. ORCID: https://orcid.org/0000-0001-9703-9777, Lee, Kwok Y., Ruge, Fiona, Farrier, Jeremy N., Enoch, Stuart, Caley, Matthew P., Peake, Matthew A., Davies, Lindsay C. ORCID: https://orcid.org/0000-0002-4876-6270, Giles, Peter J. ORCID: https://orcid.org/0000-0003-3143-6854, Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820, Stephens, Phil ORCID: https://orcid.org/0000-0002-0840-4996 and Moseley, Ryan ORCID: https://orcid.org/0000-0002-2812-6735 2023. Role of enzymic antioxidants in mediating oxidative stress and contrasting wound healing capabilities in oral mucosal/skin fibroblasts and tissues. Antioxidants 12 (7) , 1374. 10.3390/antiox12071374

Mehreen, Zakir, Thomas, David ORCID: https://orcid.org/0000-0001-7319-5820, Adams, Robert, Farnell, Damian ORCID: https://orcid.org/0000-0003-0662-1927 and Claydon, Nicholas ORCID: https://orcid.org/0000-0002-4151-1515 2023. A systematic review and meta-analysis of the clinical outcomes for adjunctive physical, chemical, and biological treatment of dental implants with peri-implantitis. Journal of Oral Implantology 49 (2) , pp. 168-178. 10.1563/aaid-joi-d-21-00204

Powell, Lydia C. ORCID: https://orcid.org/0000-0002-8641-0160, Adams, Jennifer Y.M., Quoraishi, Sadik, Py, Charlene, Oger, Anais, Gazze, Salvatore A., Francis, Lewis W., von Ruhland, Christopher, Owens, David, Rye, Philip D., Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117, Pritchard, Manon F. ORCID: https://orcid.org/0000-0002-5135-4744 and Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 2023. Alginate oligosaccharides enhance the antifungal activity of nystatin against candidal biofilms. Frontiers in Cellular and Infection Microbiology 13 , 1122340. 10.3389/fcimb.2023.1122340

Powell, Lydia C. ORCID: https://orcid.org/0000-0002-8641-0160, Cullen, Jason K., Boyle, Glen M., De Ridder, Tom, Yap, Pei-Yi, Xue, Wenya, Pierce, Carly J., Pritchard, Manon F., Menzies, Georgina E. ORCID: https://orcid.org/0000-0002-6600-6507, Abdulkarim, Muthanna, Adams, Jennifer Y. M., Stokniene, Joana, Francis, Lewis W., Gumbleton, Mark ORCID: https://orcid.org/0000-0002-7386-311X, Johns, Jenny, Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117, Jones, Adam V., Parsons, Peter G., Reddell, Paul and Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 2022. Topical, immunomodulatory epoxy-tiglianes induce biofilm disruption and healing in acute and chronic skin wounds. Science Translational Medicine 14 (662) 10.1126/scitranslmed.abn3758

Saud, Zack, Tyrrell, Victoria J., Zaragkoulias, Andreas, Protty, Majd B., Statkute, Evelina, Rubina, Anzelika, Bentley, Kirsten ORCID: https://orcid.org/0000-0002-6619-2098, White, Daniel A., Dos Santos Rodrigues, Patricia, Murphy, Robert C., Köfeler, Harald, Griffiths, William J., Alvarez-Jarreta, Jorge, Brown, Richard William, Newcombe, Robert G. ORCID: https://orcid.org/0000-0003-4400-8867, Heyman, James, Pritchard, Manon ORCID: https://orcid.org/0000-0002-5135-4744, Mcleod, Robert W. J., Arya, Arvind, Lynch, Ceri-Ann, Owens, David, Jenkins, P. Vince, Buurma, Niklaas J. ORCID: https://orcid.org/0000-0003-0260-5057, O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460, Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 and Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182 2022. The SARS-CoV2 envelope differs from host cells, exposes pro-coagulant lipids, and is disrupted in vivo by oral rinses. Journal of Lipid Research 63 (6) , 100208. 10.1016/j.jlr.2022.100208

Stokniene, Joana, Varache, Mathieu ORCID: https://orcid.org/0000-0001-7166-2253, Rye, Philip D, Hill, Katja E ORCID: https://orcid.org/0000-0002-8590-0117, Thomas, David W ORCID: https://orcid.org/0000-0001-7319-5820 and Ferguson, Elaine L ORCID: https://orcid.org/0000-0002-0125-0234 2022. Alginate oligosaccharides enhance diffusion and activity of colistin in a mucin-rich environment. Scientific Reports 12 , 4986. 10.1038/s41598-022-08927-1

Chiron, Emilie, Varache, Mathieu ORCID: https://orcid.org/0000-0001-7166-2253, Stokniene, Joana, Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 and Ferguson, Elaine L. ORCID: https://orcid.org/0000-0002-0125-0234 2021. A physicochemical assessment of the thermal stability of dextrin–colistin conjugates. Scientific Reports 11 , 10600. 10.1038/s41598-021-89946-2

Carey, Elinor Claire, Gardiner, Andrew Talbot Charles, Adams, Robert John, Farnell, Damian Joseph John ORCID: https://orcid.org/0000-0003-0662-1927, Claydon, Nicholas Charles ORCID: https://orcid.org/0000-0002-4151-1515 and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2021. The effects of age and sex on mandibular bone graft donor sites. Oral Surgery 14 (1) , pp. 52-58. 10.1111/ORS.12535

Oakley, Juliette L., Weiser, Rebecca ORCID: https://orcid.org/0000-0003-3983-3272, Powell, Lydia C. ORCID: https://orcid.org/0000-0002-8641-0160, Forton, Julian ORCID: https://orcid.org/0000-0002-0580-0432, Mahenthiralingam, Eshwar ORCID: https://orcid.org/0000-0001-9014-3790, Rye, Philip D., Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117, Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 and Pritchard, Manon F. ORCID: https://orcid.org/0000-0002-5135-4744 2021. Phenotypic and genotypic adaptations in Pseudomonas aeruginosa biofilms following long-term exposure to an alginate oligomer therapy. mSphere 6 (1) , e01216-20. 10.1128/mSphere.01216-20

Powell, Lydia C. ORCID: https://orcid.org/0000-0002-8641-0160, Abdulkarim, Muthanna, Stokniene, Joana, Yang, Qui E., Walsh, Timothy R. ORCID: https://orcid.org/0000-0003-4315-4096, Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117, Gumbleton, Mark ORCID: https://orcid.org/0000-0002-7386-311X and Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 2021. Quantifying the effects of antibiotic treatment on the extracellular polymer network of antimicrobial resistant and sensitive biofilms using multiple particle tracking. npj Biofilms and Microbiomes 7 , 13. 10.1038/s41522-020-00172-6

Jones, Timothy ORCID: https://orcid.org/0000-0002-4466-1260, Berube, Kelly ORCID: https://orcid.org/0000-0002-7471-7229, Lannon, Simon ORCID: https://orcid.org/0000-0003-4677-7184, McLeod, Robert ORCID: https://orcid.org/0000-0003-3221-6896, Claydon, Nicholas ORCID: https://orcid.org/0000-0002-4151-1515, Roberts, Ashley, Giles, Anthony ORCID: https://orcid.org/0000-0002-1221-5987 and Thomas, David ORCID: https://orcid.org/0000-0001-7319-5820 2021. The potential transmission of COVID-19 during routine dental surgery. Presented at: 8th UK–China International Particle Technology Forum 2021, Dali, Tunnan, China, 9-13 July 2021.

Stokniene, Joana, Powell, Lydia C. ORCID: https://orcid.org/0000-0002-8641-0160, Aarstad, Olav A., Aachmann, Finn L., Rye, Philip D., Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117, Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 and Ferguson, Elaine L. ORCID: https://orcid.org/0000-0002-0125-0234 2020. Bi-functional alginate oligosaccharide–polymyxin conjugates for improved treatment of multidrug-resistant gram-negative bacterial infections. Pharmaceutics 12 (11) , 1080. 10.3390/pharmaceutics12111080

Almershed, Nizar, Adams, Robert, Mort, Joelle, Farnell, Damian ORCID: https://orcid.org/0000-0003-0662-1927, Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 and Claydon, Nicholas ORCID: https://orcid.org/0000-0002-4151-1515 2020. The use of non-surgical interventions in patients with periimplantitis; a systematic review and meta-analysis. Oral Surgery 14 (2) , pp. 178-190. 10.1111/ors.12548

O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460, Thomas, David ORCID: https://orcid.org/0000-0001-7319-5820, Stanton, Richard ORCID: https://orcid.org/0000-0002-6799-1182, Maillard, Jean-Yves ORCID: https://orcid.org/0000-0002-8617-9288, Murphy, Robert C., Jones, Simon A. ORCID: https://orcid.org/0000-0001-7297-9711, Humphreys, Ian ORCID: https://orcid.org/0000-0002-9512-5337, Wakelam, Michael J. O., Fegan, Christopher ORCID: https://orcid.org/0000-0001-9685-0621, Wise, Matt P., Bosch, Albert and Sattar, Syed A. 2020. Potential role of oral rinses targeting the viral lipid envelope in SARS-CoV-2 infection. Function 1 (1) , zqaa002. 10.1093/function/zqaa002

Yang, Qiu E., MacLean, Craig, Papkou, Andrei, Pritchard, Manon ORCID: https://orcid.org/0000-0002-5135-4744, Powell, Lydia ORCID: https://orcid.org/0000-0002-8641-0160, Thomas, David ORCID: https://orcid.org/0000-0001-7319-5820, Andrey, Diego O., Li, Mei, Spiller, Brad ORCID: https://orcid.org/0000-0002-9117-6911, Yang, Wang and Walsh, Timothy R. ORCID: https://orcid.org/0000-0003-4315-4096 2020. Compensatory mutations modulate the competitiveness and dynamics of plasmid-mediated colistin resistance in Escherichia coli clones. ISME Journal 14 , pp. 861-865. 10.1038/s41396-019-0578-6

Varache, Mathieu ORCID: https://orcid.org/0000-0001-7166-2253, Powell, Lydia C. ORCID: https://orcid.org/0000-0002-8641-0160, Aarstad, Olav A., Williams, Thomas L., Wenzel, Margot N. ORCID: https://orcid.org/0000-0001-6411-1816, Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 and Ferguson, Elaine L. ORCID: https://orcid.org/0000-0002-0125-0234 2019. Polymer masked-unmasked protein therapy: Identification of the active species after amylase-activation of dextrin-colistin conjugates. Molecular Pharmaceutics 16 (7) , pp. 3199-3207. 10.1021/acs.molpharmaceut.9b00393

Roberts, AEL, Powell, LC ORCID: https://orcid.org/0000-0002-8641-0160, Pritchard, MF ORCID: https://orcid.org/0000-0002-5135-4744, Thomas, DW ORCID: https://orcid.org/0000-0001-7319-5820 and Jenkins, RE 2019. Anti-pseudomonad activity of manuka honey and antibiotics in a specialized ex vivo model simulating cystic fibrosis lung infection. Frontiers in Microbiology 10 , -. 10.3389/fmicb.2019.00869

Ferguson, Elaine L ORCID: https://orcid.org/0000-0002-0125-0234, Naseer, Sameza, Powell, Lydia C ORCID: https://orcid.org/0000-0002-8641-0160, Hardwicke, Joseph, Young, Fraser I ORCID: https://orcid.org/0000-0003-0779-3835, Zhu, Bangfu, Liu, Qian, Song, Bing ORCID: https://orcid.org/0000-0001-9356-2333 and Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 2018. Controlled release of Dextrin-conjugated growth factors to support growth and differentation of neural stem cells. Stem Cell Research 33 , pp. 69-78. 10.1016/j.scr.2018.10.008

Al-Kadhim, Karrar A. H., Pritchard, Manon ORCID: https://orcid.org/0000-0002-5135-4744, Farnell, Damian ORCID: https://orcid.org/0000-0003-0662-1927, Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820, Adams, Robert and Claydon, Nicholas ORCID: https://orcid.org/0000-0002-4151-1515 2018. Surgical therapy for peri-implantitis management: a systematic review and meta-analysis. Oral Surgery 11 (3) , pp. 200-212. 10.1111/ors.12344

Blaikie, Polly, Nishio Ayre, Wayne ORCID: https://orcid.org/0000-0003-2405-1876, Thomas, David ORCID: https://orcid.org/0000-0001-7319-5820, Begum, Taslima, Eaton, Mark ORCID: https://orcid.org/0000-0002-7388-6522, Harwood, Carly and Crivelli, Davide ORCID: https://orcid.org/0000-0002-1573-5726 2018. A smart surgical tool for optimal dental implant fixation. Presented at: 96th General Session of the IADR, London, UK, 25-28 Jul 2018.

Powell, Lydia C. ORCID: https://orcid.org/0000-0002-8641-0160, Pritchard, Manon F. ORCID: https://orcid.org/0000-0002-5135-4744, Ferguson, Elaine L. ORCID: https://orcid.org/0000-0002-0125-0234, Powell, Kate A. ORCID: https://orcid.org/0000-0002-8641-0160, Patel, Shree U., Rye, Phil D., Sakellakou, Stavroula-Melina, Buurma, Niklaas J. ORCID: https://orcid.org/0000-0003-0260-5057, Brilliant, Charles D., Copping, Jack M., Menzies, Georgina E. ORCID: https://orcid.org/0000-0002-6600-6507, Lewis, Paul D., Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117 and Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 2018. Targeted disruption of the extracellular polymeric network of pseudomonas aeruginosa biofilms by alginate oligosaccharides. npj Biofilms and Microbiomes 4 , 13. 10.1038/s41522-018-0056-3

Adams, Robert, Hamid, L., Binney, Adrian, Claydon, Nicholas ORCID: https://orcid.org/0000-0002-4151-1515, Farnell, Damian ORCID: https://orcid.org/0000-0003-0662-1927, Griffiths, B. and Thomas, David ORCID: https://orcid.org/0000-0001-7319-5820 2018. A radiographic analysis of anatomical variation at the mandibular of intraoral bone harvesting. Oral Surgery 11 (2) , pp. 105-111. 10.1111/ors.12304

Jack, Alison A., Khan, Saira, Powell, Lydia C. ORCID: https://orcid.org/0000-0002-8641-0160, Pritchard, Manon F. ORCID: https://orcid.org/0000-0002-5135-4744, Beck, Konrad ORCID: https://orcid.org/0000-0001-5098-9484, Sadh, Hina, Sutton, Lucy, Cavaliere, Alessandra, Florence, Hannah, Rye, Philip D., Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 and Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117 2018. Alginate Oligosaccharide-Induced Modification of the lasI-lasR and rhlI-rhlR Quorum Sensing Systems in Pseudomonas aeruginosa. Antimicrobial Agents and Chemotherapy 62 (5) , e02318-17. 10.1128/AAC.02318-17

Yang, Qiu, Li, Mei, Spiller, Owen B. ORCID: https://orcid.org/0000-0002-9117-6911, Andrey, Diego O., Hinchliffe, Philip, Li, Hui, MacLean, Craig, Niumsup, Pannika, Powell, Lydia ORCID: https://orcid.org/0000-0002-8641-0160, Pritchard, Manon ORCID: https://orcid.org/0000-0002-5135-4744, Papkou, Andrei, Shen, Yingbo, Portal, Edward, Sands, Kirsty, Spencer, James, Tansawai, Uttapoln, Thomas, David ORCID: https://orcid.org/0000-0001-7319-5820, Wang, Shaolin, Wang, Yang, Shen, Jianzhong and Walsh, Timothy 2017. Balancing mcr-1 expression and bacterial survival is a delicate equilibrium between essential cellular defence mechanisms. Nature Communications 8 , 2054. 10.1038/s41467-017-02149-0

Pritchard, Manon ORCID: https://orcid.org/0000-0002-5135-4744, Jack, Alison, Powell, Lydia ORCID: https://orcid.org/0000-0002-8641-0160, Sadh, Hina, Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117, Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 and Rye, Philip D 2017. Alginate Oligosaccharides modify hyphal infiltration of Candida albicans in an in vitro model of invasive Human Candidosis. Journal of Applied Microbiology 123 (3) , pp. 625-636. 10.1111/jam.13516

Pritchard, Manon F. ORCID: https://orcid.org/0000-0002-5135-4744, Powell, Lydia C. ORCID: https://orcid.org/0000-0002-8641-0160, Jack, Alison A., Powell, Kate ORCID: https://orcid.org/0000-0002-8641-0160, Beck, Konrad ORCID: https://orcid.org/0000-0001-5098-9484, Florance, Hannah, Forton, Julian, Rye, Philip D., Dessen, Arne, Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117 and Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 2017. A low-molecular-weight alginate oligosaccharide disrupts pseudomonal microcolony formation and enhances antibiotic effectiveness. Antimicrobial Agents and Chemotherapy 61 (9) , e00762-17. 10.1128/AAC.00762-17

Pritchard, Manon F. ORCID: https://orcid.org/0000-0002-5135-4744, Powell, Lydia C. ORCID: https://orcid.org/0000-0002-8641-0160, Khan, Saira, Griffiths, Peter C., Mansour, Omar T., Schweins, Ralf, Beck, Konrad ORCID: https://orcid.org/0000-0001-5098-9484, Buurma, Niklaas J. ORCID: https://orcid.org/0000-0003-0260-5057, Dempsey, Christopher E., Wright, Chris J., Rye, Philip D., Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117, Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 and Ferguson, Elaine L. ORCID: https://orcid.org/0000-0002-0125-0234 2017. The antimicrobial effects of the alginate oligomer OligoG CF-5/20 are independent of direct bacterial cell membrane disruption. Scientific Reports 7 , 44731. 10.1038/srep44731

Jack, Alison A., Nordli, Henriette R., Powell, Lydia C., Powell, Kate A., Kishnani, Himanshu, Johnsen, Per Olav, Pukstad, Brita, Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820, Chinga-Carrasco, Gary and Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117 2017. The interaction of wood nanocellulose dressings and the wound pathogen P. aeruginosa. Carbohydrate Polymers 157 , pp. 1955-1962. 10.1016/j.carbpol.2016.11.080

Pritchard, Manon F. ORCID: https://orcid.org/0000-0002-5135-4744, Powell, Lydia C. ORCID: https://orcid.org/0000-0002-8641-0160, Menzies, Georgina E. ORCID: https://orcid.org/0000-0002-6600-6507, Lewis, Paul D., Hawkins, Karl, Wright, Chris, Doull, Iolo, Walsh, Timothy R., Onsoyen, Edvar, Dessen, Arne, Myrvold, Rolf, Rye, Philip D., Myrset, Astrid H., Stevens, Howard N. E., Hodges, Lee A., MacGregor, Gordon, Neilly, James B., Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117 and Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 2016. A new class of safe oligosaccharide polymer therapy to modify the mucus barrier of chronic respiratory disease. Molecular Pharmaceutics 13 (3) , pp. 863-872. 10.1021/acs.molpharmaceut.5b00794

Powell, Lydia C. ORCID: https://orcid.org/0000-0002-8641-0160, Khan, Saira, Chinga-Carrasco, Gary, Wright, Chris J., Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117 and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2016. An investigation of Pseudomonas aeruginosa biofilm growth on novel nanocellulose fiber dressings. Carbohydrate Polymers 137 , pp. 191-197. 10.1016/j.carbpol.2015.10.024

Roberts, Jessica L., Cattoz, Beatrice, Schweins, Ralf, Beck, Konrad ORCID: https://orcid.org/0000-0001-5098-9484, Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820, Griffiths, Peter C. and Ferguson, Elaine L. ORCID: https://orcid.org/0000-0002-0125-0234 2016. In vitro evaluation of the interaction of dextrin-colistin conjugates with bacterial lipopolysaccharide. Journal of Medicinal Chemistry 59 (2) , pp. 647-654. 10.1021/acs.jmedchem.5b01521

Azzopardi, Ernest A. ORCID: https://orcid.org/0000-0002-4511-0954, Ferguson, Elaine L. ORCID: https://orcid.org/0000-0002-0125-0234 and Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 2015. Development and validation of an in vitro pharmacokinetic/pharmacodynamic model to test the antibacterial efficacy of antibiotic polymer conjugates. Antimicrobial Agents and Chemotherapy 59 (4) , pp. 1837-1843. 10.1128/AAC.03708-14

Rees, Adam, Powell, Lydia C. ORCID: https://orcid.org/0000-0002-8641-0160, Chinga-Carrasco, Gary, Gethin, David T., Syverud, Kristin, Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117 and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2015. 3D bioprinting of carboxymethylated-periodate oxidized nanocellulose constructs for wound dressing applications. BioMedical Research International 2015 , pp. 1-7. 10.1155/2015/925757

Ferguson, Elaine L. ORCID: https://orcid.org/0000-0002-0125-0234, Azzopardi, Ernest ORCID: https://orcid.org/0000-0002-4511-0954, Roberts, Jessica L., Walsh, Timothy R. ORCID: https://orcid.org/0000-0003-4315-4096 and Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 2014. Dextrin-Colistin conjugates as a model bioresponsive treatment for multidrug resistant bacterial infections. Molecular Pharmaceutics 11 (12) , pp. 4437-4447. 10.1021/mp500584u

Tondervik, Anne, Sletta, Havard, Klinkenberg, Geir, Emanuel, Charlotte, Powell, Lydia C. ORCID: https://orcid.org/0000-0002-8641-0160, Pritchard, Manon F. ORCID: https://orcid.org/0000-0002-5135-4744, Khan, Saira, Craine, Keiron M., Onsoyen, Edvar, Rye, Phil D., Wright, Chris, Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 and Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117 2014. Alginate oligosaccharides inhibit fungal cell growth and potentiate the activity of anti-fungals against Candida and Aspergillus spp. PLoS ONE , e112518. 10.1371/journal.pone.0112518

Peake, Matthew A., Caley, Mathew, Giles, Peter J. ORCID: https://orcid.org/0000-0003-3143-6854, Wall, Ivan B., Enoch, Stuart, Davies, Lindsay Catrina ORCID: https://orcid.org/0000-0002-4876-6270, Kipling, David Glyn, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 and Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996 2014. Identification of a transcriptional signature for the wound healing continuum. Wound Repair and Regeneration 22 (3) , pp. 399-405. 10.1111/wrr.12170

Powell, Lydia C. ORCID: https://orcid.org/0000-0002-8641-0160, Pritchard, Manon F. ORCID: https://orcid.org/0000-0002-5135-4744, Emanuel, Charlotte, Onsøyen, Edvar, Rye, Philip D., Wright, Chris J., Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117 and Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 2014. A nanoscale characterization of the interaction of a novel alginate oligomer with the cell surface and motility of pseudomonas aeruginosa. American Journal of Respiratory Cell and Molecular Biology 50 (3) , pp. 483-492. 10.1165/rcmb.2013-0287OC

Azzopardi, Ernest A. ORCID: https://orcid.org/0000-0002-4511-0954, Ferguson, Elaine Lesley ORCID: https://orcid.org/0000-0002-0125-0234 and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2014. A novel class of bioreponsive nanomedicines for localised reinstatement of bioactivity and specific targeting [Abstract]. The Lancet 383 , S9. 10.1016/S0140-6736(14)60272-5

McInnes, Rachael L., Cullen, Breda M., Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117, Price, Patricia E., Harding, Keith G., Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820, Stephens, Phil ORCID: https://orcid.org/0000-0002-0840-4996 and Moseley, Ryan ORCID: https://orcid.org/0000-0002-2812-6735 2014. Contrasting host immuno-inflammatory responses to bacterial challenge within venous and diabetic ulcers. Wound Repair and Regeneration 22 (1) , pp. 58-69. 10.1111/wrr.12133

Roberts, Jessica Louise, Khan, Saira, Emanuel, Charlotte, Powell, Lydia C. ORCID: https://orcid.org/0000-0002-8641-0160, Pritchard, Manon ORCID: https://orcid.org/0000-0002-5135-4744, Onsøyen, E., Myrvold, R., Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 and Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117 2013. An in vitro study of alginate oligomer therapies on oral biofilms. Journal of Dentistry 41 (10) , pp. 892-899. 10.1016/j.jdent.2013.07.011

Daw, Abdulaziz E., Kazi, Hizbullah Ashhad, Colombo, John Samuel, Rowe, Wendy Gillian, Williams, David Wynne ORCID: https://orcid.org/0000-0002-7351-5131, Waddington, Rachel J., Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 and Moseley, Ryan ORCID: https://orcid.org/0000-0002-2812-6735 2013. Differential cellular and microbial responses to nano-/micron-scale titanium surface roughness induced by hydrogen peroxide treatment. Journal of Biomaterials Applications 28 (1) , pp. 144-160. 10.1177/0885328212441495

Azzopardi, Ernest A. ORCID: https://orcid.org/0000-0002-4511-0954, Ferguson, Elaine Lesley ORCID: https://orcid.org/0000-0002-0125-0234 and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2013. Colistin past and future: A bibliographic analysis. Journal of Critical Care 28 (2) , 219.e13-219.e19. 10.1016/j.jcrc.2012.04.008

Azzopardi, Ernest A. ORCID: https://orcid.org/0000-0002-4511-0954, Ferguson, Elaine Lesley ORCID: https://orcid.org/0000-0002-0125-0234 and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2013. The enhanced permeability retention effect: a new paradigm for drug targeting in infection. Journal of Antimicrobial Chemotherapy 68 (2) , pp. 257-274. 10.1093/jac/dks379

Powell, Lydia C. ORCID: https://orcid.org/0000-0002-8641-0160, Sowedan, Ahmed, Khan, Saira, Wright, Chris J., Hawkins, Karl, Onsøyen, Edvar, Myrvold, Rolf, Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117 and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2013. The effect of alginate oligosaccharides on the mechanical properties of Gram-negative biofilms. Biofouling 29 (4) , pp. 413-421. 10.1080/08927014.2013.777954

Azzopardi, Ernest A. ORCID: https://orcid.org/0000-0002-4511-0954, Camilleri, Liberato, Moseley, Ryan ORCID: https://orcid.org/0000-0002-2812-6735, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 and Ferguson, Elaine Lesley ORCID: https://orcid.org/0000-0002-0125-0234 2013. Statistical characterization of succinoylated dextrin degradation behavior in human α-amylase. Journal of Carbohydrate Chemistry 32 (7) , pp. 438-449. 10.1080/07328303.2013.831434

Hooper, Samuel James, Percival, Steven L., Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820, Hayes, Anthony Joseph and Williams, David Wynne ORCID: https://orcid.org/0000-0002-7351-5131 2012. The visualisation and speed of kill of wound isolates on a silver alginate dressing. International Wound Journal 9 (6) , pp. 633-642. 10.1111/j.1742-481X.2012.00927.x

Khan, Saira, Tondervik, Anne, Sletta, Havard, Klinkenberg, Geir, Emanuel, Charlotte, Onsoyen, Edvar, Myrvold, Rolf, Howe, Robin A., Walsh, Timothy Rutland ORCID: https://orcid.org/0000-0003-4315-4096, Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117 and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2012. Overcoming drug resistance with alginate oligosaccharides able to potentiate the action of selected antibiotics. Antimicrobial Agents and Chemotherapy 56 (10) , pp. 5134-5141. 10.1128/AAC.00525-12

Percival, Steven L., Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117, Williams, David Wynne ORCID: https://orcid.org/0000-0002-7351-5131, Hooper, Samuel J., Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 and Costerton, John W. 2012. A review of the scientific evidence for biofilms in wounds. Wound Repair and Regeneration 20 (5) , pp. 647-657. 10.1111/j.1524-475X.2012.00836.x

Wildeboer, D., Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117, Jeganathan, F., Williams, David Wynne ORCID: https://orcid.org/0000-0002-7351-5131, Riddell, Andrew David, Price, Patricia Elaine, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820, Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Abuknesha, R. A. and Price, R. G. 2012. Specific protease activity indicates the degree of Pseudomonas aeruginosa infection in chronic infected wounds. European Journal of Clinical Microbiology & Infectious Diseases 31 (9) , pp. 2183-2189. 10.1007/s10096-012-1553-6

Wagstaffe, Sarah Jayne, Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117, Williams, David Wynne ORCID: https://orcid.org/0000-0002-7351-5131, Randle, Beverley J., Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820, Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996 and Riley, D. Jason 2012. Bispecific antibody-mediated detection of the staphylococcus aureus thermonuclease. Analytical Chemistry 84 (14) , pp. 5876-5884. 10.1021/ac203403d

Hooper, Samuel James, Williams, David Wynne ORCID: https://orcid.org/0000-0002-7351-5131, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820, Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117 and Percival, S. L. 2012. An in vitro comparison of two silver- containing antimicrobial wound dressings. Ostomy Wound Management 58 (1) , pp. 16-22.

Ferguson, Elaine Lesley ORCID: https://orcid.org/0000-0002-0125-0234, Roberts, Jessica Louise, Moseley, Ryan ORCID: https://orcid.org/0000-0002-2812-6735, Griffiths, Peter Charles and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2011. Evaluation of the physical and biological properties of hyaluronan and hyaluronan fragments. International Journal of Pharmaceutics 420 (1) , pp. 84-92. 10.1016/j.ijpharm.2011.08.031

Hardwicke, Joseph, Hart, Jeff, Bell, Andrea, Duncan, Ruth, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 and Moseley, Ryan ORCID: https://orcid.org/0000-0002-2812-6735 2011. The effect of dextrin-rhEGF on the healing of full-thickness, excisional wounds in the (db/db) diabetic mouse. Journal of Controlled Release 152 (3) , pp. 411-417. 10.1016/j.jconrel.2011.03.016

Percival, S. L., Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117, Malic, Sladjana, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 and Williams, David Wynne ORCID: https://orcid.org/0000-0002-7351-5131 2011. Antimicrobial tolerance and the significance of persister cells in recalcitrant chronic wound biofilms. Wound Repair and Regeneration 19 (1) , pp. 1-9. 10.1111/j.1524-475X.2010.00651.x

Malic, Sladjana, Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117, Playle, Rebecca Anne ORCID: https://orcid.org/0000-0002-2989-1092, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 and Williams, David Wynne ORCID: https://orcid.org/0000-0002-7351-5131 2011. In vitro interaction of chronic wound bacteria in biofilms. Journal of Wound Care 20 (12) , pp. 569-577.

Enoch, Stuart, Peake, Matthew Arnold, Wall, Ivan Bernard, Davies, Lindsay Catrina ORCID: https://orcid.org/0000-0002-4876-6270, Farrier, Jerry N., Giles, Peter James ORCID: https://orcid.org/0000-0003-3143-6854, Kipling, David Glyn, Price, Patricia Elaine, Moseley, Ryan ORCID: https://orcid.org/0000-0002-2812-6735, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 and Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996 2010. 'Young' oral fibroblasts are geno/phenotypically distinct. Journal of Dental Research 89 (12) , pp. 1407-1413. 10.1177/0022034510377796

Ferguson, Elaine Lesley ORCID: https://orcid.org/0000-0002-0125-0234, Alshame, Alshame Mohamed J. and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2010. Evaluation of hyaluronic acid-protein conjugates for polymer masked-unmasked protein therapy. International Journal of Pharmaceutics 402 (1-2) , pp. 95-102. 10.1016/j.ijpharm.2010.09.029

Pukstad, Brita S., Ryan, Liv, Flo, Trude H., Stenvik, Jørgen, Moseley, Ryan ORCID: https://orcid.org/0000-0002-2812-6735, Harding, Keith Gordon, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 and Espevik, T. 2010. Non-healing is associated with persistent stimulation of the innate immune response in chronic venous leg ulcers. Journal of Dermatological Science 59 (2) , pp. 115-122. 10.1016/j.jdermsci.2010.05.003

Hardwicke, Joseph, Moseley, Ryan ORCID: https://orcid.org/0000-0002-2812-6735, Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Harding, Keith Gordon, Duncan, Ruth and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2010. Bioresponsive dextrin-rhEGF conjugates: in vitro evaluation in models relevant to its proposed use as a treatment for chronic wounds. Molecular Pharmaceutics 7 (3) , pp. 699-707. 10.1021/mp9002656

Davies, Lindsay Catrina ORCID: https://orcid.org/0000-0002-4876-6270, Locke, Matthew, Webb, Richard D. J., Roberts, James T., Langley, Martin Simon, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820, Archer, Charles William and Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996 2010. A multipotent neural crest derived progenitor cell population is resident within the oral mucosa lamina propria. Stem Cells and Development 19 (6) , pp. 819-830. 10.1089/scd.2009.0089

Simpson, Russell M. L., Wells, Alan, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820, Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2010. Aging fibroblasts resist phenotypic maturation because of impaired hyaluronan-dependent CD44/epidermal growth factor receptor signaling. American Journal of Pathology 176 (3) , pp. 1215-1228. 10.2353/ajpath.2010.090802

Hardwicke, Joseph., Song, Bing ORCID: https://orcid.org/0000-0001-9356-2333, Moseley, Ryan ORCID: https://orcid.org/0000-0002-2812-6735 and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2010. Investigation of the potential of polymer therapeutics in corneal re-epithelialisation. British Journal of Ophthalmology 94 (12) , pp. 1566-1570. 10.1136/bjo.2009.177295

Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117, Malic, Sladjana, McKee, Ruth, Rennison, Tracy, Harding, Keith Gordon, Williams, David Wynne ORCID: https://orcid.org/0000-0002-7351-5131 and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2010. An in vitro model of chronic wound biofilms to test wound dressings and assess antimicrobial susceptibilities. Journal of Antimicrobial Chemotherapy 65 (6) , pp. 1195-1206. 10.1093/jac/dkq105

Simpson, Russell M. L., Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820, Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2009. Age-related changes in pericellular hyaluronan organization leads to impaired dermal fibroblast to myofibroblast differentiation. American Journal of Pathology 175 (5) , pp. 1915-1928. 10.2353/ajpath.2009.090045

Enoch, Stuart, Wall, Ivan Bernard, Peake, Matthew Arnold, Davies, Lindsay Catrina ORCID: https://orcid.org/0000-0002-4876-6270, Farrier, Jerry N., Giles, Peter James ORCID: https://orcid.org/0000-0003-3143-6854, Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467, Kipling, David Glyn, Price, Patricia Elaine, Moseley, Ryan ORCID: https://orcid.org/0000-0002-2812-6735, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 and Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996 2009. Increased oral fibroblast lifespan is telomerase-independent. Journal of Dental Research 88 (10) , pp. 916-921. 10.1177/0022034509342979

Iversen, Ann-Charlotte, Steinkjer, Bjorg, Nilsen, Nadra, Bohnhorst, Janne, Moen, Siv Helen, Vik, Randi, Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820, Benedict, Chris A. and Espevik, Terje. 2009. A proviral role for CpG in cytomegalovirus infection. Journal of Immunology 182 (9) , pp. 5672-5681. 10.4049/jimmunol.0801268

Simpson, Russell M.L., Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Thomas, David ORCID: https://orcid.org/0000-0001-7319-5820, Webber, J. P., Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978, Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2009. Age related changes in pericellular hyaluronan leads to impaired dermal fibroblast to myofibroblast differentiation. International Journal of Experimental Pathology 90 (2) , A128-A129.

Cook, H., Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Davies, K. J., Harding, Keith Gordon and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2009. Phenotypic differences in wound healing responses are reflected by differences in ECM reorganisation and MMP-2 activation. Journal of Gastroenterology and Hepatology 24 , A88-A88. 10.1046/j.1365-2613.2000.0145k.x

Malic, Sladjana, Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117, Hayes, Anthony Joseph, Percival, S. L., Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 and Williams, David Wynne ORCID: https://orcid.org/0000-0002-7351-5131 2009. Detection and identification of specific bacteria in wound biofilms using peptide nucleic acid fluorescent in situ hybridization (PNA FISH). Microbiology-Sgm 155 , pp. 2603-2611. 10.1099/mic.0.028712-0

Roberts, J., Drage, Nicholas, Davies, J. and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2009. Effective dose from cone beam CT examinations in dentistry. British Journal of Radiology 82 (973) , pp. 35-40. 10.1259/bjr/31419627

Wall, Ivan Bernard, Moseley, Ryan ORCID: https://orcid.org/0000-0002-2812-6735, Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467, Kipling, David Glyn, Giles, Peter James ORCID: https://orcid.org/0000-0003-3143-6854, Laffafian, Iraj, Price, Patricia Elaine, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 and Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996 2008. Fibroblast dysfunction is a key factor in the non-healing of chronic venous leg ulcers. Journal of Investigative Dermatology 128 (10) , pp. 2526-2540. 10.1038/jid.2008.114

Hardwicke, Joseph, Ferguson, Elaine Lesley ORCID: https://orcid.org/0000-0002-0125-0234, Moseley, Ryan ORCID: https://orcid.org/0000-0002-2812-6735, Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 and Duncan, Ruth 2008. Dextrin-rhEGF conjugates as bioresponsive nanomedicines for wound repair. Journal of Controlled Release 130 (3) , pp. 275-283. 10.1016/j.jconrel.2008.07.023

Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820, Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Enoch, Stuart, Martin, John, Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2008. Hyaluronan facilitates transforming growth factor-β1-mediated fibroblast proliferation. Journal of Biological Chemistry 283 (10) , pp. 6530-6545. 10.1074/jbc.M704819200

Enoch, S., Moseley, Ryan ORCID: https://orcid.org/0000-0002-2812-6735, Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996 and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2008. The oral mucosa: A model of wound healing with reduced scarring. Oral Surgery 1 , pp. 11-21. 10.1111/j.1752-248x.2007.00005.x

Peake, Matthew Arnold, Giles, Peter James ORCID: https://orcid.org/0000-0003-3143-6854, Wall, Ivan Bernard, Enoch, Stuart, Kipling, David Glyn, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 and Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996 2008. Identifying a Gene signature for the wound healing continuum [Abstract]. Wound Repair and Regeneration 16 (6) , A71. 10.1111/j.1524-475X.2008.00424.x

Nagassa, M. E., Daw, A. E., Rowe, Wendy Gillian, Carley, Albert Frederick, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 and Moseley, Ryan ORCID: https://orcid.org/0000-0002-2812-6735 2008. Optimisation of the hydrogen peroxide pre-treatment of titanium: surface characterisation and protein adsorption. Clinical Oral Implants Research 19 (12) , pp. 1317-1326. 10.1111/j.1600-0501.2008.01611.x

Hardwicke, Joseph, Schmaljohann, D., Boyce, D. and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2008. Epidermal growth factor therapy and wound healing - past, present and future. Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland 6 (3) , pp. 172-177. 10.1016/S1479-666X(08)80114-X

Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978, Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 and Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996 2008. Hyaluronan facilitates TGF beta 1 mediated myofibroblastic differentiation [Abstract]. Wound Repair and Regeneration 16 (2) , A12. 10.1111/j.1524-475X.2008.00371.x

Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820, Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Martin, John, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 and Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 2007. Involvement of hyaluronan in regulation of fibroblast phenotype. The Journal of Biological Chemistry 282 (35) , pp. 25687-25697. 10.1074/jbc.M700773200

Malic, Sladjana, Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117, Ralphs, James Robert ORCID: https://orcid.org/0000-0002-5367-0732, Hayes, Anthony Joseph, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820, Potts, Albert John Cornel and Williams, David Wynne ORCID: https://orcid.org/0000-0002-7351-5131 2007. Characterisation of Candida albicans infection of an in vitro oral epithelial model using confocal laser scanning microscopy. Oral Microbiology And Immunolology 22 (3) , pp. 188-194. 10.1111/j.1399-302X.2007.00344.x

Davies, Charlotte Emma, Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117, Newcombe, Robert Gordon ORCID: https://orcid.org/0000-0003-4400-8867, Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Wilson, Melanie ORCID: https://orcid.org/0000-0002-8834-8268, Harding, Keith Gordon and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2007. A prospective study of the microbiology of chronic venous leg ulcers to re-evaluate the clinical predictive value of tissue biopsies and swabs. Wound Repair and Regeneration 15 (1) , pp. 17-22. 10.1111/j.1524-475X.2006.00180.x

Andersen, A., Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117, Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820, Jorgensen, B. and Krogfelt, K. A. 2007. Bacterial profiling using skin grafting, standard culture and molecular bacteriological methods. Journal of Wound Care 16 (4) , pp. 171-175.

Seager, Joanna Mary, Howell-Jones, Rebecca Sian, Dunstan, Frank David John ORCID: https://orcid.org/0000-0002-1043-5281, Lewis, Michael Alexander Oxenham ORCID: https://orcid.org/0000-0003-1917-0651, Richmond, Stephen ORCID: https://orcid.org/0000-0001-5449-5318 and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2006. A randomised controlled trial of clinical outreach education to rationalise antibiotic prescribing for acute dental pain in the primary care setting. British Dental Journal 201 (4) , pp. 217-222. 10.1038/sj.bdj.4813879

Howell-Jones, Rebecca, Price, Patricia Elaine, Howard, Anthony J. and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2006. Antibiotic prescribing for chronic skin wounds in primary care. Wound Repair and Regeneration 14 (4) , pp. 387-393. 10.1111/j.1743-6109.2006.00144.x

Tebble, Nicola, Adams, Robert, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 and Price, Patricia Elaine 2006. Anxiety and self-consciousness in patients with facial lacerations one week and six months later. British Journal of Oral & Maxillofacial Surgery 44 (6) , pp. 520-525. 10.1016/j.bjoms.2005.10.010

Howell-Jones, R. S., Wilson, Melanie ORCID: https://orcid.org/0000-0002-8834-8268, Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117, Howard, A. J., Price, Patricia Elaine and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2005. A review of the microbiology, antibiotic usage and resistance in chronic skin wounds. Journal of Antimicrobial Chemotherapy 55 (2) , pp. 143-149. 10.1093/jac/dkh513

Moseley, Ryan ORCID: https://orcid.org/0000-0002-2812-6735, Hilton, Joanna Ruth, Waddington, Rachel J., Harding, Keith Gordon, Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996 and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2004. Comparison of oxidative stress biomarker profiles between acute and chronic wound environments. Wound Repair and Regeneration 12 (4) , pp. 419-429. 10.1111/j.1067-1927.2004.12406.x

Davies, Charlotte E., Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117, Wilson, Melanie ORCID: https://orcid.org/0000-0002-8834-8268, Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Hill, C. Michael, Harding, Keith Gordon and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2004. Use of 16S ribosomal DNA PCR and denaturing gradient gel electrophoresis for analysis of the microfloras of healing and non-healing chronic venous leg ulcers. Journal of Clinical Microbiology 42 (8) , pp. 3549-3557. 10.1128/JCM.42.8.3549-3557.2004

Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Grenard, Pascale Marie, Aeschlimann, Pascale Corinne, Langley, Martin Simon, Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254, Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376, Kipling, David Glyn, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 and Aeschlimann, Daniel ORCID: https://orcid.org/0000-0003-0930-7706 2004. Crosslinking and G-protein functions of transglutaminase 2 contribute differentially to fibroblast wound healing responses. Journal of cell science 117 (15) , pp. 3389-3403. 10.1242/jcs.01188

Enoch, Stuart, Price, Patricia Elaine, Harding, Keith Gordon, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 and Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996 2004. Identifying the molecular and genetic basis for non-healing wounds, scarless healing and scarring: study of human fibroblasts. British Journal of Surgery 91 (S1) , p. 82.

Moseley, Ryan ORCID: https://orcid.org/0000-0002-2812-6735, Stewart, J. E., Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Waddington, Rachel J. ORCID: https://orcid.org/0000-0001-5878-1434 and Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 2004. Extracellular matrix metabolites as potential biomarkers of disease activity in wound fluid: lessons learned from other inflammatory diseases? British Journal of Dermatology 150 (3) , pp. 401-413. 10.1111/j.1365-2133.2004.05845.x

Moseley, Ryan ORCID: https://orcid.org/0000-0002-2812-6735, Hilton, Joanna R., Waddington, Rachel J. ORCID: https://orcid.org/0000-0001-5878-1434, Harding, Keith Gordon, Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996 and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2004. Comparison of oxidative stress biomarker profiles between acute and chronic wound environments. Wound Repair and Regeneration 12 (4) , pp. 419-429. 10.1111/j.1067-1927.2004.12406.x

Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117, Davies, Clare Elizabeth, Wilson, Melanie ORCID: https://orcid.org/0000-0002-8834-8268, Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Harding, Keith Gordon and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2003. Molecular analysis of the microflora in chronic venous leg ulceration. Journal of Medical Microbiology 52 (4) , pp. 365-369. 10.1099/jmm.0.05030-0

Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Wall, Ivan Bernard, Wilson, Melanie ORCID: https://orcid.org/0000-0002-8834-8268, Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117, Davies, Charlotte Emma, Hill, C. Michael, Harding, Keith Gordon and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2003. Anaerobic cocci populating the deep tissues of chronic wounds impair cellular wound healing responses in vitro. British Journal Of Dermatology 148 (3) , pp. 456-466. 10.1046/j.1365-2133.2003.05232.x

Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Cook, Helen, Hilton, Joanne, Jones, Christopher John, Haughton, Michele Fleur, Wyllie, Fiona Sandra, Skinner, Julia W., Harding, Keith Gordon, Kipling, David Glyn and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2003. An analysis of replicative senescence in dermal fibroblasts derived from chronic leg wounds predicts that telomerase therapy would fail to reverse their disease-specific cellular and proteolytic phenotype. Experimental Cell Research 283 (1) , pp. 22-35. 10.1016/S0014-4827(02)00021-6

White, Philip, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820, Fong, Steven, Stelnicki, Eric, Meijlink, Fritz, Largman, Corey and Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996 2003. Deletion of the homeobox gene PRX-2 affects fetal but not adult fibroblast wound healing responses. Journal Of Investigative Dermatology 120 (1) , pp. 135-144. 10.1046/j.1523-1747.2003.12015.x

Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117, Davies, Charlotte Emma, Wilson, Melanie ORCID: https://orcid.org/0000-0002-8834-8268, Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Lewis, Michael Alexander Oxenham ORCID: https://orcid.org/0000-0003-1917-0651, Hall, Val, Brazier, J. S. and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2002. Heterogeneity within the gram-positive anaerobic cocci demonstrated by analysis of 16S-23S intergenic ribosomal RNA polymorphisms. Journal of Medical Microbiology 51 (11) , pp. 949-957.

Wall, Ivan B., Davies, Charlotte E., Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117, Wilson, Melanie J., Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Harding, Keith Gordon and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2002. Potential role of anaerobic cocci in impaired human wound healing. Wound Repair and Regeneration 10 (6) , pp. 346-353. 10.1046/j.1524-475X.2002.t01-1-10602.x

Wall, Steven J., Bevan, Damon, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820, Harding, Keith Gordon, Edwards, Dylan R. and Murphy, Gillian 2002. Differential expression of matrix metalloproteinases during impaired wound healing of the diabetes mouse. Journal of Investigative Dermatology 119 (1) , pp. 91-98. 10.1046/j.1523-1747.2002.01779.x

Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996 and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2002. The cellular proliferative phase of the wound repair process. Journal of Wound Care 11 (7) , pp. 253-261. 10.12968/jowc.2002.11.7.26421

Wall, Steven J., Bevan, Damon, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820, Harding, Keith Gordon, Edwards, Dylan R. and Murphy, Gillian 2002. Differential expression of matrix matalloproteinases during impaired wound healing of the diabetes mouse. Journal of Investigative Dermatology 119 (1) , pp. 91-98. 10.1046/j.1523-1747.2002.01779.x

Davies, Charlotte E., Wilson, Melanie J., Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117, Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Hill, C. Michael, Harding, Keith Gordon and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2001. Use of molecular techniques to study microbial diversity in the skin: Chronic wounds reevaluated. Wound Repair and Regeneration 9 (5) , pp. 332-340. 10.1046/j.1524-475x.2001.00332.x

Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820, Baboolal, Kesh ORCID: https://orcid.org/0000-0002-3688-9353, Subramanian, N. and Newcombe, Robert Gordon ORCID: https://orcid.org/0000-0003-4400-8867 2001. Cyclosporin A-induced gingival overgrowth is unrelated to allograft function in renal transplant recipients. Journal of clinical periodontology 28 (7) , pp. 706-709. 10.1034/j.1600-051x.2001.028007706.x

Hill, C. Michael, Balkenohl, M., Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820, Walker, Rita Valerie, Mathe, H. and Murray, G. 2001. Pregabalin in patients with postoperative dental pain. European Journal of Pain 5 (2) , pp. 119-124. 10.1053/eujp.2001.0235

Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Davies, Kathryn June, Occleston, N., Pleass, R. D., Kon, C., Daniels, J., Khaw, P. T. and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2001. Skin and oral fibroblasts exhibit phenotypic differences in extracellular matrix reorganization and matrix metalloproteinase activity. British Journal Of Dermatology 144 (2) , pp. 229-237. 10.1046/j.1365-2133.2001.04006.x

Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Cook, Helen, Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111, Zhiquiang, Wu and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 2001. Phenotypic variation in the production of bioactive hepatocyte growth factor/scatter factor by oral mucosal and skin fibroblasts. Wound Repair and Regeneration 9 (1) , pp. 34-43. 10.1046/j.1524-475x.2001.00034.x

Cook, Helen, Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Davies, K. June, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 and Harding, Keith Gordon 2000. Defective Extracellular Matrix Reorganization by Chronic Wound Fibroblasts is Associated with Alterations in TIMP-1, TIMP-2, and MMP-2 Activity. Journal of Investigative Dermatology 115 (2) , pp. 225-233. 10.1046/j.1523-1747.2000.00044.x

Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820, Hill, C. Michael, Lewis, Michael A. O., Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Walker, Rita and Von Der Weth, Andreas 2000. Randomized clinical trial of the effect of semi-occlusive dressings on the microflora and clinical outcome of acute facial wounds. Wound Repair and Regeneration 8 (4) , pp. 258-263. 10.1046/j.1524-475x.2000.00258.x

Stephens, Mark, Lim, Kenneth, Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Lim, S. H. and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 1998. Molecular characterisation of tumour infiltrating lymphocytes in oral squamous cell carcinoma. Cancer Immunology, Immunotherapy 46 (1) , pp. 34-40. 10.1007/s002620050457

Lim, S. H., Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Cao, Q.X., Coleman, Sharon Louise and Thomas, David ORCID: https://orcid.org/0000-0001-7319-5820 1997. Molecular analysis of T cell receptor beta variability in a patient with orofacial granulomatosis. Gut 40 (5) , pp. 683-686. 10.1136/gut.40.5.683

Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820, Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Stephens, M., Patten, D. W. and Lim, S. H. 1997. T-cell receptor Vbeta usage by lesional lymphocytes in oral lichen planus. Journal of Oral Pathology & Medicine 26 (3) , pp. 105-109. 10.1111/j.1600-0714.1997.tb00031.x

al-Khateeb, Taiseer, Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Shepherd, Jonathan ORCID: https://orcid.org/0000-0001-6466-2298 and Thomas, David ORCID: https://orcid.org/0000-0001-7319-5820 1997. An investigation of preferential fibroblast wound repopulation using a novel in vitro wound model. Journal of Periodontology 68 (11) , pp. 1063-1069. 10.1902/jop.1997.68.11.1063

Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Davies, K. J., Al-Khateeb, T., Shepherd, Jonathan Paul ORCID: https://orcid.org/0000-0001-6466-2298 and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 1996. A comparison of the ability of intra-oral and extra-oral fibroblasts to stimulate extracellular matrix reorganization in a model of wound contraction. Journal of Dental Research 75 (6) , pp. 1358-1364. 10.1177/00220345960750060601

Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Al-Khateeb, T., Davies, K. J., Shepherd, Jonathan Paul ORCID: https://orcid.org/0000-0001-6466-2298 and Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 1996. An investigation of the interaction between alcohol and fibroblasts in wound healing. International Journal of Oral and Maxillofacial Surgery 25 (2) , pp. 161-164. 10.1016/S0901-5027(96)80065-8