Ninkina, Natalia, Millership, Steven J., Peters, Owen M., Connor-Robson, Natalie, Chaprov, Kirill, Kopylov, Arthur T., Montoya, Alex, Kramer, Holger, Withers, Dominic J. and Buchman, Vladimir L.
2021.
β-synuclein potentiates synaptic vesicle dopamine uptake and rescues dopaminergic neurons from MPTP-induced death in the absence of other synucleins.
Journal of Biological Chemistry
297
(6)
, 101375.
10.1016/j.jbc.2021.101375
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Peters, Owen M., Weiss, Alexandra, Metterville, Jake, Song, Lina, Logan, Robert, Smith, Gaynor A., Schwarzschild, Michael A., Mueller, Christian, Brown, Robert H. and Freeman, Marc
2021.
Genetic diversity of axon degenerative mechanisms in models of Parkinson's disease.
Neurobiology of Disease
155
, 105368.
10.1016/j.nbd.2021.105368
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Hsu, Jiun-Min, Kang, Yunsik, Corty, Megan M., Mathieson, Danielle, Peters, Owen M. and Freeman, Marc R. 2021. Injury-induced inhibition of bystander neurons requires dSarm and signaling from glia. Neuron 109 (3) , pp. 473-487. 10.1016/j.neuron.2020.11.012 |
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Malik, Bilal R., Maddison, Daniel C., Smith, Gaynor A. and Peters, Owen M.
2019.
Autophagic and endo-lysosomal dysfunction in neurodegenerative disease.
Molecular Brain
12
(1)
, 100.
10.1186/s13041-019-0504-x
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Peters, Owen, Lewis, Elizabeth A, Osterloh, Jeannette M, Weiss, Alexandra, Salameh, Johnny S, Metterville, Jake, Brown, Robert H and Freeman, Marc R 2018. Loss of Sarm1 does not suppress motor neuron degeneration in the SOD1G93A mouse model of amyotrophic lateral sclerosis. Human Molecular Genetics 27 (21) , pp. 3761-3771. 10.1093/hmg/ddy260 |
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White, Matthew A., Kim, Eosu, Duffy, Amanda, Adalbert, Robert, Phillips, Benjamin U., Peters, Owen M., Stephenson, Jodie, Yang, Sujeong, Massenzio, Francesca, Lin, Ziqiang, Andrews, Simon, Segonds-Pichon, Anne, Metterville, Jake, Saksida, Lisa M., Mead, Richard, Ribchester, Richard R., Barhomi, Youssef, Serre, Thomas, Coleman, Michael P., Fallon, Justin, Bussey, Timothy J., Brown, Robert H. and Sreedharan, Jemeen
2018.
TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD.
Nature Neuroscience
21
(4)
, pp. 552-563.
10.1038/s41593-018-0113-5
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Fil, Daniel, DeLoach, Abigail, Yadav, Shilpi, Alkam, Duah, MacNicol, Melanie, Singh, Awantika, Compadre, Cesar M., Goellner, Joseph J., O'Brien, Charles A., Fahmi, Tariq, Basnakian, Alexei G., Calingasan, Noel Y., Klessner, Jodi L., Beal, Flint M., Peters, Owen Morgan, Metterville, Jake, Brown, Robert H., Ling, Karen K.Y., Rigo, Frank, Ozdinler, P. Hande and Kiaei, Mahmoud 2017. Mutant profilin1 transgenic mice recapitulate cardinal features of motor neuron disease. Human Molecular Genetics 26 (4) , pp. 686-701. 10.1093/hmg/ddw429 |
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Connor-Robson, Natalie, Peters, Owen, Millership, Steven, Ninkina, Natalia and Buchman, Vladimir L. 2016. Combinational losses of synucleins reveal their differential requirements for compensating age-dependent alterations in motor behavior and dopamine metabolism. Neurobiology of Aging 46 , pp. 107-112. 10.1016/j.neurobiolaging.2016.06.020 |
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Peters, Owen M., Cabrera, Gabriela Toro, Tran, Helene, Gendron, Tania F., McKeon, Jeanne E., Metterville, Jake, Weiss, Alexandra, Wightman, Nicholas, Salameh, Johnny, Kim, Juhyun, Sun, Huaming, Boylan, Kevin B., Dickson, Dennis, Kennedy, Zachary, Lin, Ziqiang, Zhang, Yong-Jie, Daughrity, Lillian, Jung, Chris, Gao, Fen-Biao, Sapp, Peter C., Horvitz, H. Robert, Bosco, Daryl A., Brown, Solange P., de Jong, Pieter, Petrucelli, Leonard, Mueller, Christian and Brown, Robert H. 2015. Human C9ORF72 hexanucleotide expansion reproduces RNA foci and dipeptide repeat proteins but not neurodegeneration in BAC transgenic mice. Neuron 88 (5) , pp. 902-909. 10.1016/j.neuron.2015.11.018 |
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Peters, Owen M., Ghasemi, Mehdi and Brown, Robert H. 2015. Emerging mechanisms of molecular pathology in ALS. The Journal of Clinical Investigation 125 (5) , pp. 1767-1779. 10.1172/JCI71601 |
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Peters, Owen Morgan, Shelkovnikova, Tatyana, Highley, John Robin, Cooper-Knock, Johnathan, Hortobágyi, Tibor, Troakes, Claire, Ninkina, Natalia and Buchman, Vladimir L. 2015. Gamma-synuclein pathology in amyotrophic lateral sclerosis. Annals of Clinical and Translational Neurology 2 (1) , pp. 29-37. 10.1002/acn3.143 |
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Shelkovnikova, Tatyana, Peters, Owen Morgan, Deykin, Alexey V., Connor-Robson, Natalie, Robinson, Hannah, Ustyugov, Aleksey, Bachurin, Sergey O., Ermolkevich, Tatyana G., Goldman, Igor L., Sadchikova, Elena R., Kovrazhkina, Elena A., Skvortsova, Veronica I., Ling, Shuo-Chien, Da Cruz, Sandrine, Parone, Philippe A., Buchman, Vladimir L. and Ninkina, Natalia 2013. Fused in sarcoma (FUS) protein lacking nuclear localization signal (NLS) and major RNA binding motifs triggers proteinopathy and severe motor phenotype in transgenic mice. Journal of Biological Chemistry 288 (35) , pp. 25266-25274. 10.1074/jbc.M113.492017 |
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Peters, Owen Morgan, Shelkovnikova, Tatyana, Tarasova, Tatiana, Springe, Signe, Kukharsky, Michail S., Smith, Gaynor A., Brooks, Simon Philip, Kozin, Sergey A., Kotelevtsev, Yury, Bachurin, Sergey O., Ninkina, Natalia and Buchman, Vladimir L. 2013. Chronic administration of dimebon does not ameliorate amyloid-β pathology in 5xFAD transgenic mice. Journal of Alzheimer's Disease 36 (3) , pp. 589-596. 10.3233/JAD-130071 |
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Peters, Owen Morgan, Connor-Robson, Natalie, Sokolov, V. B., Aksinenko, A. Y., Kukharsky, M. S., Bachurin, S. O., Ninkina, Natalia and Buchman, Vladimir L. 2013. Chronic administration of dimebon ameliorates pathology in Tau P301S transgenic mice. Journal of Alzheimer's Disease 33 (4) , pp. 1041-1049. 10.3233/JAD-2012-121732 |
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Ninkina, Natalia, Peters, Owen Morgan, Connor-Robson, Natalie, Lytkina, Olga, Sharfeddin, Essam and Buchman, Vladimir L. 2012. Contrasting effects of α-Synuclein and γ-Synuclein on the phenotype of cysteine string protein α (CSPα) null mutant mice suggest distinct function of these proteins in neuronal synapses. Journal of Biological Chemistry 287 (53) , pp. 44471-44477. 10.1074/jbc.M112.422402 |
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Peters, Owen Morgan, Millership, Steven, Shelkovnikova, Tatyana, Soto, Ileana, Keeling, Lora, Hann, Anthona, Marsh-Armstrong, Nicholas, Buchman, Vladimir L. and Ninkina, Natalia 2012. Selective pattern of motor system damage in gamma-synuclein transgenic mice mirrors the respective pathology in amyotrophic lateral sclerosis. Neurobiology of Disease 48 (1) , pp. 124-131. 10.1016/j.nbd.2012.06.016 |
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Bachurin, Sergey O., Shelkovnikova, Tatyana, Ustyugov, Alexey A., Peters, Owen Morgan, Khritankova, Ina, Afanasieva, Marina A., Tarasova, Tatyana V., Alentov, Igor I., Buchman, Vladimir L. and Ninkina, Natalia 2012. Dimebon slows progression of proteinopathy in γ-synuclein transgenic mice. Neurotoxicity Research 22 (1) , pp. 33-42. 10.1007/s12640-011-9299-y |
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Ustyugov, A. A., Shelkovnikova, Tatyana, Kokhan, V. S., Khritankova, I. V., Peters, Owen Morgan, Buchman, Vladimir L., Bachurin, S. O. and Ninkina, Natalia 2012. Dimebon reduces the levels of aggregated amyloidogenic protein forms in detergent-insoluble fractions in vivo. Bulletin of Experimental Biology and Medicine 152 (6) , pp. 731-733. 10.1007/s10517-012-1618-7 |
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Shelkovnikova, Tatyana, Kulikova, A. A., Tsvetkov, Ph. O., Peters, Owen Morgan, Bachurin, S. O., Buchman, Vladimir L. and Ninkina, Natalia 2012. Proteinopathies, neurodegenerative disorders with protein aggregation-based pathology. Molecular Biology 46 (3) , pp. 362-374. 10.1134/S0026893312020161 |
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Anwar, Shabana, Peters, Owen Morgan, Millership, Steven, Ninkina, Natalia, Doig, N., Connor-Robson, Natalie, Threlfell, Sarah, Kooner, Gurdeep, Deacon, R., Bannerman, D., Bolam, J., Chandra, S., Cragg, Sarah, Wade- Martins, Richard and Buchman, Vladimir L. 2011. Functional alterations to the nigrostriatal system in mice lacking all three members of the synuclein family. Journal of Neuroscience 31 (20) , pp. 7264-7274. 10.1523/JNEUROSCI.6194-10.2011 |
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Shelkovnikova, Tatyana, Ustyugov, Alexey, Millership, Steven, Peters, Owen Morgan, Anichtchik, Oleg, Spillantini, Maria Grazia, Buchman, Vladimir L., Bachurin, Sergey and Ninkina, Natalia 2011. Dimebon does not ameliorate pathological changes caused by expression of truncated (1-120) human alpha-synuclein in dopaminergic neurons of transgenic mice. Neurodegenerative Diseases 8 (6) , pp. 430-437. 10.1159/000324989 |
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Peters, Owen 2011. Gamma-synucleinopathy in mice (and humans?). PhD Thesis, Cardiff University. |
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Ninkina, Natalia, Peters, Owen Morgan, Millership, Steven, Salem, Hatem Omar, Van der Putten, Herman and Buchman, Vladimir L. 2009. y-Synucleinopathy: neurodegeneration associated with overexpression of the mouse protein. Human Molecular Genetics 18 (10) , pp. 1779-1794. 10.1093/hmg/ddp090 |
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King, Jason, Teo, Regina, Ryves, William Jonathan, Reddy, Jonathan Venkat, Peters, Owen Morgan, Orabi, Ben, Hoeller, Oliver, Williams, Robin S. B. and Harwood, Adrian John 2009. The mood stabiliser lithium suppresses PIP3 signalling in 'Dictyostelium' and human cells. Disease Models & Mechanisms 2 (5-6) , pp. 306-312. 10.1242/dmm.001271 |
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