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Number of items: 115.

Ulamec, Sabine M., Maya-Martinez, Roberto, Byrd, Emily J., Dewison, Katherine M., Xu, Yong, Willis, Leon F., Sobott, Frank, Heath, George R., van Oosten Hawle, Patricija, Buchman, Vladimir L., Radford, Sheena E. and Brockwell, David J. 2022. Single residue modulators of amyloid formation in the N-terminal P1-region of α-synuclein. Nature Communications 13 (1) , 4986. 10.1038/s41467-022-32687-1

Carnazza, Kathryn E., Komer, Lauren E., Xie, Ying Xue, Pineda, André, Briano, Juan Antonio, Gao, Virginia, Na, Yoonmi, Ramlall, Trudy, Buchman, Vladimir L., Eliezer, David, Sharma, Manu and Burré, Jacqueline 2022. Synaptic vesicle binding of α-synuclein is modulated by β- and γ-synucleins. Cell Reports 39 (2) , 110675. 10.1016/j.celrep.2022.110675

An, Haiyan, Litscher, Gioana, Watanabe, Naruaki, Wei, Wenbin, Hashimoto, Tadafumi, Iwatsubo, Takeshi, Buchman, Vladimir L and Shelkovnikova, Tatyana A 2022. ALS-linked cytoplasmic FUS assemblies are compositionally different from physiological stress granules and sequester hnRNPA3, a novel modifier of FUS toxicity. Neurobiology of Disease 162 , 105585. 10.1016/j.nbd.2021.105585

Chaprov, Kirill D., Lysikova, Ekaterina A., Teterina, Ekaterina V. and Buchman, Vladimir L. 2021. Kinetics of alpha-synuclein depletion in three brain regions following conditional pan-neuronal inactivation of the encoding gene (Snca) by tamoxifen-induced Cre-recombination in adult mice. Transgenic Research 30 , pp. 867-873. 10.1007/s11248-021-00286-3

Ninkina, Natalia, Millership, Steven J., Peters, Owen M., Connor-Robson, Natalie, Chaprov, Kirill, Kopylov, Arthur T., Montoya, Alex, Kramer, Holger, Withers, Dominic J. and Buchman, Vladimir L. 2021. β-synuclein potentiates synaptic vesicle dopamine uptake and rescues dopaminergic neurons from MPTP-induced death in the absence of other synucleins. Journal of Biological Chemistry 297 (6) , 101375. 10.1016/j.jbc.2021.101375

Upcott, Matthew, Chaprov, Kirill D. and Buchman, Vladimir 2021. Towards disease-modifying therapy of alpha-synucleinopathies: new molecules and new approaches came into the lime-light. Molecules 26 (23) , 7351. 10.3390/molecules26237351

Kukharsky, Michail S., Skvortsova, Veronika I., Bachurin, Sergey O. and Buchman, Vladimir L. 2021. In a search for efficient treatment for amyotrophic lateral sclerosis: Old drugs for new approaches. Medicinal Research Reviews 41 (5) , pp. 2804-2822. 10.1002/med.21725

Chaprov, Kirill, Rezvykh, Alexander, Funikov, Sergei, Ivanova, Tamara, Lysikova, Ekaterina, Deykin, Alexei, Kukharsky, Michail, Aksinenko, Alexey, Bachurin, Sergey, Ninkina, Natalia and Buchman, Vladimir 2021. A bioisostere of Dimebon/Latrepirdine delays the onset and slows the progression of pathology in FUS transgenic mice. CNS Neuroscience and Therapeutics 27 (7) , pp. 765-775. 10.1111/cns.13637

Guschina, Irina A., Ninkina, Natalia, Roman, Andrei, Pokrovskiy, Mikhail V. and Buchman, Vladimir L. 2021. Triple-knockout, synuclein-free mice display compromised lipid pattern. Molecules 26 (11) , 3078. 10.3390/molecules26113078

Hosford, Patrick S., Ninkina, Natalia, Buchman, Vladimir L., Smith, Jeffrey C., Marina, Nephtali and SheikhBahaei, Shahriar 2020. Synuclein deficiency results in age-related respiratory and cardiovascular dysfunctions in mice. Brain Sciences 10 (9) , 583. 10.3390/brainsci10090583

Ninkina, Natalia, Tarasova, Tatiana V., Chaprov, Kirill D., Roman, Andrei Yu, Kukharsky, Michail S., Kolik, Larisa G., Ovchinnikov, Ruslan, Ustyugov, Aleksey A., Durnev, Andrey D. and Buchman, Vladimir L. 2020. Alterations in the nigrostriatal system following conditional inactivation of α-synuclein in neurons of adult and aging mice. Neurobiology of Aging 91 , pp. 76-87. 10.1016/j.neurobiolaging.2020.02.026

Lysikova, Ekaterina A., Funikov, Sergei, Rezvykh, Alexander P., Chaprov, Kirill D., Kukharsky, Michail S., Ustyugov, Aleksey, Deykin, Alexey V., Flyamer, Ilya A., Boyle, Shelagh, Bachurin, Sergey O., Ninkina, Natalia and Buchman, Vladimir 2020. Low level of expression of C-terminally truncated human FUS causes extensive changes in the spinal cord transcriptome of asymptomatic transgenic mice. Neurochemical Research 45 , pp. 1168-1179. 10.1007/s11064-020-02999-z

Kukharsky, Michail S., Ninkina, Natalia N., An, Haiyan, Telezhkin, Vsevolod, Wei, Wenbin, Rabesahala de Meritens, Camille, Cooper-Knock, Johnathan, Nakagawa, Shinichi, Hirose, Tetsuro, Buchman, Vladimir L. and Shelkovnikova, Tatyana A. 2020. Long non-coding RNA Neat1 regulates adaptive behavioural response to stress in mice. Translational Psychiatry 10 , 171. 10.1038/s41398-020-0854-2

An, Haiyan, Rabesahala de Meritens, Camille, Buchman, Vladimir L and Shelkovnikova, Tatyana A 2020. Frameshift peptides alter the properties of truncated FUS proteins in ALS-FUS. Molecular Brain 13 , 77. 10.1186/s13041-020-00618-0

Goloborshcheva, Valeria V., Chaprov, Kirill D., Teterina, Ekaterina V., Ovchinnikov, Ruslan and Buchman, Vladimir L. 2020. Reduced complement of dopaminergic neurons in the substantia nigra pars compacta of mice with a constitutive “low footprint” genetic knockout of alpha-synuclein. Molecular Brain 13 (1) , 75. 10.1186/s13041-020-00613-5

Shelkovnikova, Tatyana A., An, Haiyan, Skelt, Lucy, Tregoning, John S., Humphreys, Ian R. and Buchman, Vladimir L. 2019. Antiviral immune response as a trigger of FUS proteinopathy in amyotrophic lateral sclerosis. Cell Reports 29 (13) , 4496-4508.e4. 10.1016/j.celrep.2019.11.094

Lysikova, Ekaterina A, Kukharsky, Michail S, Chaprov, Kirill D, Vasilieva, Nataliia A, Roman, Andrei Y, Ovchinnikov, Ruslan K, Deykin, Alexey V, Ninkina, Natalia and Buchman, Vladimir L 2019. Behavioural impairments in mice of a novel FUS transgenic line recapitulate features of frontotemporal lobar degeneration. Genes, Brain and Behavior 18 (8) , e12607. 10.1111/gbb.12607

Ninkina, Natalia, Kukharsky, Michail S, Hewitt, Maria V, Lysikova, Ekaterina A, Skuratovska, Larissa N, Deykin, Alexey V and Buchman, Vladimir 2019. Stem cells in human breast milk. Human Cell 32 (3) , pp. 223-230. 10.1007/s13577-019-00251-7

Egorova, Tatiana V., Zotova, Evgenia D., Reshetov, Denis A., Polikarpova, Anna V., Vassilieva, Svetlana G., Vlodavets, Dmitry V., Gavrilov, Alexey A., Ulianov, Sergey V., Buchman, Vladimir L. and Deykin, Alexei V. 2019. CRISPR/Cas9-generated mouse model of Duchenne muscular dystrophy recapitulating a newly identified large 430 kb deletion in the human DMD gene. Disease Models and Mechanisms 12 (4) , -. 10.1242/dmm.037655

An, Haiyan, Skelt, Lucy, Notaro, Antonietta, Highley, J. Robin, Fox, Archa H., La Bella, Vincenzo, Buchman, Vladimir L. and Shelkovnikova, Tatyana A. 2019. ALS-linked FUS mutations confer loss and gain of function in the nucleus by promoting excessive formation of dysfunctional paraspeckles. Acta Neuropathologica Communications 7 , 7. 10.1186/s40478-019-0658-x

Skvortsova, V.I., Bachurin, S.O., Ustyugov, A.A., Kukharsky, M.S., Deikin, A.V., Buchman, Vladimir L. and Ninkina, Natalia 2018. Gamma-carbolines derivatives as promising agents for the development of pathogenic therapy for proteinopathy. Acta Naturae 10 (4) , pp. 59-62.

Shelkovnikova, Tatyana A., Kukharsky, Michail S., An, Haiyan, Dimasi, Pasquale, Alexeeva, Svetlana, Shabir, Osman, Heath, Paul R. and Buchman, Vladimir L. 2018. Protective paraspeckle hyper-assembly downstream of TDP-43 loss of function in amyotrophic lateral sclerosis. Molecular Neurodegeneration 13 , 30. 10.1186/s13024-018-0263-7

Shelkovnikova, Tatyana, Dimasi, Pasquale, Kukharsky, Michail S., An, Haiyan, Quintiero, Annamaria, Schirmer, Claire, Buée, Luc, Galas, Marie-Christine and Buchman, Vladimir L. 2017. Chronically stressed or stress-preconditioned neurons fail to maintain stress granule assembly. Cell Death and Disease 8 , e2788. 10.1038/cddis.2017.199

Roman, Andrei Yu, Limorenko, Galina, Ustyugov, Alexey A., Tarasova, Tatiana, Lysikova, Ekaterina A., Buchman, Vladimir L. and Ninkina, Natalia 2017. Generation of mouse lines with conditionally or constitutively inactivated Snca gene and Rosa26-stop-lacZ reporter located in cis on the mouse chromosome 6. Transgenic Research 26 (2) , pp. 301-307. 10.1007/s11248-016-9995-8

Dimasi, Pasquale, Quintiero, Annamaria, Shelkovnikova, Tatyana and Buchman, Vladimir L. 2017. Modulation of p-eIF2α cellular levels and stress granule assembly/disassembly by trehalose. Scientific Reports 7 , 44088. 10.1038/srep44088

Ludtmann, Marthe H. R., Angelova, Plamena R., Ninkina, Natalia N., Gandhi, Sonia, Buchman, Vladimir L. and Abramov, Andrey Y. 2016. Monomeric alpha-synuclein exerts a physiological role on brain ATP synthase. Journal of Neuroscience 36 (41) , pp. 10510-10521. 10.1523/JNEUROSCI.1659-16.2016

Connor-Robson, Natalie, Peters, Owen, Millership, Steven, Ninkina, Natalia and Buchman, Vladimir L. 2016. Combinational losses of synucleins reveal their differential requirements for compensating age-dependent alterations in motor behavior and dopamine metabolism. Neurobiology of Aging 46 , pp. 107-112. 10.1016/j.neurobiolaging.2016.06.020

Khatlani, Tanvir, Pradhan, Subhashree, Da, Qi, Shaw, Tanner, Buchman, Vladimir L, Cruz, Miguel A. and Vijayan, K. Vinod 2016. A novel interaction of the catalytic subunit of protein phosphatase 2A with the adaptor protein CIN85 suppresses phosphatase activity and facilitates platelet outside-in ?IIb?3Integrin Signaling. The Journal of Biological Chemistry 291 (33) , pp. 17360-17368. 10.1074/jbc.M115.704296

Fares, Mohamed-Bilal, Maco, Bohumil, Oueslati, Abid, Rockenstein, Edward, Ninkina, Natalia, Buchman, Vladimir L., Masliah, Eliezer and Lashuel, Hilal A. 2016. Induction of de novo α-synuclein fibrillization in a neuronal model for Parkinson's disease. Proceedings of the National Academy of Sciences 113 (7) , E912-E921. 10.1073/pnas.1512876113

Machhada, Asif, Ang, Richard, Ackland, Gareth L., Ninkina, Natalia, Buchman, Vladimir L., Lythgoe, Mark F., Trapp, Stefan, Tinker, Andrew, Marina, Nephtali and Gourine, Alexander V. 2015. Control of ventricular excitability by neurons of the dorsal motor nucleus of the vagus nerve. Heart Rhythm 12 (11) , pp. 2285-2293. 10.1016/j.hrthm.2015.06.005

Ninkina, Natalia, Connor-Robson, Natalie, Ustyugov, Alexey A., Tarasova, Tatiana, Shelkovnikova, Tatyana and Buchman, Vladimir L. 2015. A novel resource for studying function and dysfunction of α-synuclein: mouse lines for modulation of endogenous Snca gene expression. Scientific Reports 5 , 16615. 10.1038/srep16615

Abramycheva, Natalya Y., Lysogorskaia, Elena V., Stepanova, Maria S., Zakharova, Maria N., Kovrazhkina, Elena A., Razinskaya, Olga D., Smirnov, Andrey P., Maltsev, Andrey V., Ustyugov, Alexey A., Kukharsky, Michail S., Khritankova, Inna V., Bachurin, Sergey O., Cooper-Knock, Johnathan, Buchman, Vladimir L., Illarioshkin, Sergey N., Skvortsova, Veronika I. and Ninkina, Natalia 2015. C9ORF72 hexanucleotide repeat expansion in ALS patients from the Central European Russia population. Neurobiology of Aging 36 (10) , 2908.e5-2908.e9. 10.1016/j.neurobiolaging.2015.07.004

Bronovitsky, E. V., Deikin, A. V., Ermolkevich, T. G., Elyakov, A. B., Fedorov, E. N., Sadchikova, E. R., Goldman, I. L., Ovchinnikov, R. K., Roman, A. Yu., Khritankova, I. V., Kukharsky, M. S., Buchman, Vladimir L., Bachurin, S. O. and Ustyugov, A. A. 2015. Gamma-carboline inhibits neurodegenerative processes in a transgenic model of amyotrophic lateral sclerosis. Doklady Biochemistry and Biophysics 462 (1) , pp. 189-192. 10.1134/S1607672915030138

Kukharsky, Michail S., Quintiero, Annamaria, Matsumoto, Taisei, Matsukawa, Koji, An, Haiyan, Hashimoto, Tadafumi, Iwatsubo, Takeshi, Buchman, Vladimir L. and Shelkovnikova, Tatyana A. 2015. Calcium-responsive transactivator (CREST) protein shares a set of structural and functional traits with other proteins associated with amyotrophic lateral sclerosis. Molecular Neurodegeneration 10 , 20. 10.1186/s13024-015-0014-y

Reed, Karen Ruth, Korobko, Igor, Ninkina, Natalia, Korobko, Elena V., Hopkins, Ben R., Platt, James L., Buchman, Vladimir and Clarke, Alan Richard 2015. Hunk/Mak-v is a negative regulator of intestinal cell proliferation. BMC Cancer 15 , 110. 10.1186/s12885-015-1087-2

Peters, Owen Morgan, Shelkovnikova, Tatyana, Highley, John Robin, Cooper-Knock, Johnathan, Hortobágyi, Tibor, Troakes, Claire, Ninkina, Natalia and Buchman, Vladimir L. 2015. Gamma-synuclein pathology in amyotrophic lateral sclerosis. Annals of Clinical and Translational Neurology 2 (1) , pp. 29-37. 10.1002/acn3.143

Robinson, Hannah, Deykin, Alexey V., Bronovitsky, Evgeny V., Ovchinnikov, Ruslan K., Ustyugov, Alexey A., Shelkovnikova, Tatyana, Kukharsky, Michail S., Ermolkevich, Tatyana G., Goldman, Igor L., Sadchikova, Elena R., Kovrazhkina, Elena A., Bachurin, Sergey O., Buchman, Vladimir L. and Ninkina, Natalia 2015. Early lethality and neuronal proteinopathy in mice expressing cytoplasm-targeted FUS that lacks the RNA recognition motif. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 16 (5-6) , pp. 402-409. 10.3109/21678421.2015.1040994

Shelkovnikova, Tatyana A., Robinson, Hannah K., Southcombe, Joshua A., Ninkina, Natalia and Buchman, Vladimir L. 2014. Multistep process of FUS aggregation in the cell cytoplasm involves RNA-dependent and RNA-independent mechanisms. Human Molecular Genetics 23 (19) , pp. 5211-5226. 10.1093/hmg/ddu243

Shelkovnikova, Tatyana, Robinson, Hannah, Troakes, C., Ninkina, Natalia and Buchman, Vladimir 2014. Compromised paraspeckle formation as a pathogenic factor in FUSopathies. Human Molecular Genetics 23 (9) , pp. 2298-2312. 10.1093/hmg/ddt622

Cooper-Knock, Johnathan, Higginbottom, Adrian, Connor-Robson, Natalie, Bayatti, Nadhim, Bury, Joanna J., Kirby, Janine, Ninkina, Natalia, Buchman, Vladimir L. and Shaw, Pamela J. 2013. C9ORF72 transcription in a frontotemporal dementia case with two expanded alleles. Neurology 81 (19) , pp. 1719-1721. 10.1212/01.wnl.0000435295.41974.2e

Shelkovnikova, Tatyana, Robinson, Hannah, Connor-Robson, Natalie and Buchman, Vladimir L. 2013. Recruitment into stress granules prevents irreversible aggregation of FUS protein mislocalized to the cytoplasm. Cell Cycle 12 (19) , pp. 3194-3202. 10.4161/cc.26241

Garcia-Reitboeck, Pablo, Anichtchik, Oleg, Dalley, Jeffrey W., Ninkina, Natalia, Tofaris, George K., Buchman, Vladimir L. and Spillantini, Maria Grazia 2013. Endogenous alpha-synuclein influences the number of dopaminergic neurons in mouse substantia nigra. Experimental Neurology 248 , pp. 541-545. 10.1016/j.expneurol.2013.07.015

Jones, Ashley R., Woollacott, Ione, Shatunov, Aleksey, Cooper-Knock, Johnathan, Buchman, Vladimir L., Sproviero, William, Smith, Bradley, Scott, Kirsten M., Balendra, Rubika, Abel, Olubunmi, McGuffin, Peter, Ellis, Catherine M., Shaw, Pamela J., Morrison, Karen E., Farmer, Anne, Lewis, Cathryn M., Leigh, P. Nigel, Shaw, Christopher E., Powell, John F. and Al-Chalabi, Ammar 2013. Residual association at C9orf72 suggests an alternative amyotrophic lateral sclerosis-causing hexanucleotide repeat. Neurobiology of Aging 34 (9) , 2234.e1-2234.e7. 10.1016/j.neurobiolaging.2013.03.003

Shelkovnikova, Tatyana, Peters, Owen Morgan, Deykin, Alexey V., Connor-Robson, Natalie, Robinson, Hannah, Ustyugov, Aleksey, Bachurin, Sergey O., Ermolkevich, Tatyana G., Goldman, Igor L., Sadchikova, Elena R., Kovrazhkina, Elena A., Skvortsova, Veronica I., Ling, Shuo-Chien, Da Cruz, Sandrine, Parone, Philippe A., Buchman, Vladimir L. and Ninkina, Natalia 2013. Fused in sarcoma (FUS) protein lacking nuclear localization signal (NLS) and major RNA binding motifs triggers proteinopathy and severe motor phenotype in transgenic mice. Journal of Biological Chemistry 288 (35) , pp. 25266-25274. 10.1074/jbc.M113.492017

Buchman, Vladimir L., Cooper-Knock, Johnathan, Connor-Robson, Natalie, Higginbottom, Adrian, Kirby, Janine, Razinskaya, Olga D., Ninkina, Natalia and Shaw, Pamela J. 2013. Simultaneous and independent detection of C9ORF72 alleles with low and high number of GGGGCC repeats using an optimised protocol of Southern blot hybridisation. Molecular Neurodegeneration 8 (1) , 12. 10.1186/1750-1326-8-12

Peters, Owen Morgan, Shelkovnikova, Tatyana, Tarasova, Tatiana, Springe, Signe, Kukharsky, Michail S., Smith, Gaynor A., Brooks, Simon Philip, Kozin, Sergey A., Kotelevtsev, Yury, Bachurin, Sergey O., Ninkina, Natalia and Buchman, Vladimir L. 2013. Chronic administration of dimebon does not ameliorate amyloid-β pathology in 5xFAD transgenic mice. Journal of Alzheimer's Disease 36 (3) , pp. 589-596. 10.3233/JAD-130071

Millership, Steven, Ninkina, Natalia, Guschina, Irina, Norton, Jessica, Brambilla, Riccardo, Oort, Pieter J., Adams, Sean H., Dennis, Rowena J., Voshol, Peter J., Rochford, Justin J. and Buchman, Vladimir L. 2013. Correction for Millership et al., Increased lipolysis and altered lipid homeostasis protect  -synuclein-null mutant mice from diet-induced obesity. Proceedings of the National Academy of Sciences of the United States of America 110 (13) , p. 5269. 10.1073/pnas.1302920110

Peters, Owen Morgan, Connor-Robson, Natalie, Sokolov, V. B., Aksinenko, A. Y., Kukharsky, M. S., Bachurin, S. O., Ninkina, Natalia and Buchman, Vladimir L. 2013. Chronic administration of dimebon ameliorates pathology in Tau P301S transgenic mice. Journal of Alzheimer's Disease 33 (4) , pp. 1041-1049. 10.3233/JAD-2012-121732

Millership, Steven, Ninkina, Natalia, Rochford, Justin J. and Buchman, Vladimir L. 2013. γ-synuclein is a novel player in the control of body lipid metabolism. Adipocyte 2 (4) , pp. 276-280. 10.4161/adip.25162

Ninkina, Natalia, Peters, Owen Morgan, Connor-Robson, Natalie, Lytkina, Olga, Sharfeddin, Essam and Buchman, Vladimir L. 2012. Contrasting effects of α-Synuclein and γ-Synuclein on the phenotype of cysteine string protein α (CSPα) null mutant mice suggest distinct function of these proteins in neuronal synapses. Journal of Biological Chemistry 287 (53) , pp. 44471-44477. 10.1074/jbc.M112.422402

Millership, Steven, Ninkina, Natalia, Guschina, Irina, Norton, Jessica, Brambilla, Riccardo, Oort, Pieter J., Adams, Sean H., Dennis, Rowena J., Voshol, Peter J., Rochford, Justin J. and Buchman, Vladimir L. 2012. Increased lipolysis and altered lipid homeostasis protect γ-synuclein–null mutant mice from diet-induced obesity. Proceedings of the National Academy of Sciences of the United States of America 109 (51) , pp. 20943-20948. 10.1073/pnas.1210022110

Samoylenko, A., Vynnytska-Myronovska, B., Byts, N, Kozlova, N., Basaraba, O., Pasichnyk, G., Palyvoda, K., Bobak, Y., Barska, M., Mayevska, O., Rzhepetsky, Y., Shuvayeva, H., Lyzogubov, V., Usenko, V., Savran, V., Volodko, N., Buchman, Vladimir L., Kietzmann, T. and Drobot, L. 2012. Increased levels of the HER1 adaptor protein Ruk(l)/CIN85 contribute to breast cancer malignancy. Carcinogenesis 33 (10) , pp. 1976-1984. 10.1093/carcin/bgs228

Peters, Owen Morgan, Millership, Steven, Shelkovnikova, Tatyana, Soto, Ileana, Keeling, Lora, Hann, Anthona, Marsh-Armstrong, Nicholas, Buchman, Vladimir L. and Ninkina, Natalia 2012. Selective pattern of motor system damage in gamma-synuclein transgenic mice mirrors the respective pathology in amyotrophic lateral sclerosis. Neurobiology of Disease 48 (1) , pp. 124-131. 10.1016/j.nbd.2012.06.016

Shelkovnikova, Tatyana, Ninkina, Natalia and Buchman, Vladimir L. 2012. In Vivo properties of mutant FUS variants. Febs Journal 279 (Supp1) , p. 446. 10.1111/j.1742-4658.2010.08705.x

Kokhan, V. S., Bolkunov, A. V., Ustiugov, A. A., Van'kin, G. I., Shelkovnikova, Tatyana, Redkozubova, O. M., Strekalova, T. V., Buchman, Vladimir L., Ninkina, Natalia and Bachurin, S. O. 2012. Targeted inactivation of the gene encoding gamma-synuclein affects anxiety levels and investigative activity in mice. Neuroscience and Behavioral Physiology 42 (6) , pp. 575-581. 10.1007/s11055-012-9603-1

Bachurin, Sergey O., Shelkovnikova, Tatyana, Ustyugov, Alexey A., Peters, Owen Morgan, Khritankova, Ina, Afanasieva, Marina A., Tarasova, Tatyana V., Alentov, Igor I., Buchman, Vladimir L. and Ninkina, Natalia 2012. Dimebon slows progression of proteinopathy in γ-synuclein transgenic mice. Neurotoxicity Research 22 (1) , pp. 33-42. 10.1007/s12640-011-9299-y

Peña-Oliver, Y., Buchman, Vladimir L., Dalley, J. W., Robbins, T. W., Schumann, G., Ripley, T. L., King, S. L. and Stephens, D. N. 2012. Deletion of alpha-synuclein decreases impulsivity in mice. Genes, Brain and Behavior 11 (2) , pp. 137-146. 10.1111/j.1601-183X.2011.00758.x

Kalinichenko, Svetlana V., Itoh, Keiji, Korobko, Elena V., Sokol, Sergei Y., Buchman, Vladimir L. and Korobko, Igor V. 2012. Identification of Nedd4 E3 ubiquitin ligase as a binding partner and regulator of MAK-V protein kinase. PLoS ONE 7 (6) , e39505. 10.1371/journal.pone.0039505

Ustyugov, A. A., Shelkovnikova, Tatyana, Kokhan, V. S., Khritankova, I. V., Peters, Owen Morgan, Buchman, Vladimir L., Bachurin, S. O. and Ninkina, Natalia 2012. Dimebon reduces the levels of aggregated amyloidogenic protein forms in detergent-insoluble fractions in vivo. Bulletin of Experimental Biology and Medicine 152 (6) , pp. 731-733. 10.1007/s10517-012-1618-7

Shelkovnikova, Tatyana, Kulikova, A. A., Tsvetkov, Ph. O., Peters, Owen Morgan, Bachurin, S. O., Buchman, Vladimir L. and Ninkina, Natalia 2012. Proteinopathies, neurodegenerative disorders with protein aggregation-based pathology. Molecular Biology 46 (3) , pp. 362-374. 10.1134/S0026893312020161

Anwar, Shabana, Peters, Owen Morgan, Millership, Steven, Ninkina, Natalia, Doig, N., Connor-Robson, Natalie, Threlfell, Sarah, Kooner, Gurdeep, Deacon, R., Bannerman, D., Bolam, J., Chandra, S., Cragg, Sarah, Wade- Martins, Richard and Buchman, Vladimir L. 2011. Functional alterations to the nigrostriatal system in mice lacking all three members of the synuclein family. Journal of Neuroscience 31 (20) , pp. 7264-7274. 10.1523/JNEUROSCI.6194-10.2011

Guschina, Irina, Millership, Steven, O'Donnell, Valerie Bridget, Ninkina, Natalia, Harwood, John and Buchman, Vladimir L. 2011. Lipid classes and fatty acid patterns are altered in the brain of γ-synuclein null mutant mice. Lipids 46 (2) , pp. 121-130. 10.1007/s11745-010-3486-0

Nguyen, J. V., Soto, I., Kim, K.-Y., Bushong, E. A., Oglesby, E., Valiente-Soriano, F. J., Yang, Z., Davis, C.-H. O., Bedont, J. L., Son, J. L., Wei, J. O., Buchman, Vladimir L., Zack, D. J., Vidal-Sanz, M., Ellisman, M. H. and Marsh-Armstrong, N. 2011. Myelination transition zone astrocytes are constitutively phagocytic and have synuclein dependent reactivity in glaucoma. Proceedings of the National Academy of Sciences 108 (3) , pp. 1176-1181. 10.1073/pnas.1013965108

Shelkovnikova, Tatyana, Ustyugov, A. A., Smirnov, A. P., Skvortsova, V. I., Buchman, Vladimir L., Bachurin, S. O. and Ninkina, Natalia 2011. FUS gene mutations associated with familiar forms of amyotrophic lateral sclerosis affect cellular localization and aggregation properties of the encoded protein. Doklady Biochemistry and Biophysics 438 (1) , pp. 123-126. 10.1134/S1607672911030045

Shelkovnikova, Tatyana, Ustyugov, Alexey, Millership, Steven, Peters, Owen Morgan, Anichtchik, Oleg, Spillantini, Maria Grazia, Buchman, Vladimir L., Bachurin, Sergey and Ninkina, Natalia 2011. Dimebon does not ameliorate pathological changes caused by expression of truncated (1-120) human alpha-synuclein in dopaminergic neurons of transgenic mice. Neurodegenerative Diseases 8 (6) , pp. 430-437. 10.1159/000324989

Venda, Lara Lourenço, Cragg, Stephanie J., Buchman, Vladimir L. and Wade-Martins, Richard 2010. α-Synuclein and dopamine at the crossroads of Parkinson's disease. Trends in Neurosciences 33 (12) , pp. 559-568. 10.1016/j.tins.2010.09.004

Greten-Harrison, Becket, Polydoro, Manuela, Morimoto-Tomita, Megumi, Diao, Ling, Williams, Andrew M., Nie, Esther H., Makani, Sachin, Tian, Ning, Castillo, Pablo E., Buchman, Vladimir L. and Chandra, Sreeganga S. 2010. αβγ-Synuclein triple knockout mice reveal age-dependent neuronal dysfunction. Proceedings of the National Academy of Sciences of the United States of America 107 (45) , pp. 19573-19578. 10.1073/pnas.1005005107

Korobko, Igor, Kalinichenko, Svetlana, Korobko, Elena, Ninkina, Natalia, Kiselev, Sergey and Buchman, Vladimir L. 2010. Pro-survival activity of the MAK-V protein kinase in PC12 cells [Letter]. Cell Cycle 9 (20) , pp. 4248-4249. 10.4161/cc.9.20.13592

Burre, Jacqueline, Sharma, Manu, Tsetsenis, Theodoros, Buchman, Vladimir L., Etherton, Mark R. and Sudhof, Thomas C. 2010. α-Synuclein promotes SNARE-complex assembly in vivo and in vitro. Science 329 (5999) , pp. 1663-1667. 10.1126/science.1195227

Peña-Oliver, Yolanda, Buchman, Vladimir L. and Stephens, David 2010. Lack of involvement of alpha-synuclein in unconditioned anxiety in mice. Behavioural Brain Research 209 (2) , pp. 234-240. 10.1016/j.bbr.2010.01.049

Havrylov, Serhiy, Redowicz, Maria Jolanta and Buchman, Vladimir L. 2010. Emerging roles of Ruk/CIN85 in vesicle-mediated transport, adhesion, migration and malignancy. Traffic 11 (6) , pp. 721-731. 10.1111/j.1600-0854.2010.01061.x

Al-Wandi, Abdelmojib, Ninkina, Natalia, Millership, Steven, Williamson, S. J. M., Jones, P. A. and Buchman, Vladimir L. 2010. Absence of α-synuclein affects dopamine metabolism and synaptic markers in the striatum of aging mice. Neurobiology of Aging 31 (5) , pp. 796-804. 10.1016/j.neurobiolaging.2008.11.001

Ninkina, Natalia, Peters, Owen Morgan, Millership, Steven, Salem, Hatem Omar, Van der Putten, Herman and Buchman, Vladimir L. 2009. y-Synucleinopathy: neurodegeneration associated with overexpression of the mouse protein. Human Molecular Genetics 18 (10) , pp. 1779-1794. 10.1093/hmg/ddp090

Sato, Y., Shimizu, M., Mizunoya, W., Wariishi, H., Tatsumi, R., Buchman, Vladimir L. and Ikeuchi, Y. 2009. Differential Expression of Sarcoplasmic and Myofibrillar Proteins of Rat Soleus Muscle during Denervation Atrophy. Bioscience Biotechnology and Biochemistry 73 (8) , pp. 1748-1756. 10.1271/bbb.90085

Bachurin, S. O., Ustyugov, A. A., Peters, O., Shelkovnikova, Tatyana, Buchman, Vladimir L. and Ninkina, Natalia 2009. Hindering of proteinopathy-induced neurodegeneration as a new mechanism of action for neuroprotectors and cognition enhancing compounds. Doklady Biochemistry and Biophysics 428 (1) , pp. 235-238. 10.1134/S1607672909050032

Nikolaienko, O., Skrypkina, I., Tsyba, L., Fedyshyn, Y., Morderer, D., Buchman, Vladimir L., De La Luna, S., Drobot, L. and Rynditch, A. 2009. Intersectin 1 forms a complex with adaptor protein Ruk/CIN85 in vivo independently of epidermal growth factor stimulation. Cellular Signalling 21 (5) , pp. 753-759. 10.1016/j.cellsig.2009.01.013

Yamashita, M., Nonaka, T., Arai, T., Kametani, F., Buchman, Vladimir L., Ninkina, Natalia, Bachurin, S. O., Akiyama, H., Goedert, M. and Hasegawa, M. 2009. Methylene blue and dimebon inhibit aggregation of TDP-43 in cellular models. FEBS Letters 583 (14) , pp. 2419-2424. 10.1016/j.febslet.2009.06.042

Havrylov, S., Ichioka, F., Powell, K., Borthwick, E. B., J, Baranska, Maki, M. and Buchman, Vladimir L. 2008. Adaptor protein Ruk/CIN85 is associated with a subset of COPI coated membranes of the Golgi complex. Traffic 9 (5) , pp. 798-812. 10.1111/j.1600-0854.2008.00724.x

Senior, Steven, Ninkina, Natalia, Deacon, Robert, Bannerman, David, Buchman, Vladimir L., Cragg, Stephanie and Wade-Martins, Richard 2008. Increased striatal dopamine release and hyperdopaminergic-like behaviour in mice lacking both alpha-synuclein and gamma-synuclein. European Journal of Neuroscience 27 (4) , pp. 947-957. 10.1111/j.1460-9568.2008.06055.x

Mertsalov, I. B., Ninkina, Natalia, Wanless, J. S., Buchman, Vladimir, Korochkin, L. I. and Kulikova, D. A. 2008. Generation of mutant mice with targeted disruption of two members of the d4 gene family: neuro-d4 and cer-d4. Doklady Biochemistry and Biophysics 419 , pp. 65-68. 10.1134/S1607672908020051

Akil, O., Weber, C. M., Park, S. N., Ninkina, Natalia, Buchman, Vladimir and Lustig, L. R. 2008. Localization of Syncleins in the Mammalian Cochlea. JARO-Journal of the Association for Research in Otolaryngology 9 (4) , pp. 452-463. 10.1007/s10162-008-0134-y

Buchman, Vladimir and Ninkina, Natlia 2008. Modulation of α-synuclein expression in transgenic animals for modelling synucleinopathies-is the juice worth the squeeze? Neurotoxicity Research 14 (4) , pp. 329-341.

Ninkina, Natalia, Ustiugov, A. A. and Buchman, Vladimir 2008. Modelling synucleinopathies in genetically modified animals - successes and failures. Molekulyarnaya Biologiya 42 (5) , 747 -761. 10.1134/S0026893308050129

Oort, P. J., Knotts, T. A., Grino, M., Naour, N., Bastard, J., Clement, K., Ninkina, Natalia, Buchman, Vladimir L., Permana, P. A., Luo, X., Pan, G., Dunn, T. N. and Adams, S. H. 2008. y-Synuclein is an Adipocyte-Neuron Gene Coordinately-Expressed with Leptin and Increased in Human Obesity. Journal of Nutrition 135 (5) , pp. 841-848.

Kuhn, Melanie, Haebig, Karina, Bonin, Michael, Ninkina, Natalia, Buchman, Vladimir L., Poths, Sven and Riess, Olaf 2007. Whole genome expression analyses of single- and double-knock-out mice implicate partially overlapping functions of alpha- and gamma-synuclein. Neurogenetics 8 (2) , pp. 71-81. 10.1007/s10048-007-0079-z

Ichioka, Fumitaka, Takaya, Emi, Suzuki, Hironori, Kajigaya, Sachiko, Buchman, Vladimir L., Shibata, Hideki and Maki, Masatoshi 2007. HD-PTP and Alix share some membrane-traffic related proteins that interact with their Bro1 domains or proline-rich regions. Archives of biochemistry and biophysics 457 (2) , pp. 142-149. 10.1016/

Korobko, I. V., Korobko, E. V., Ninkina, Natalia, Buchman, Vladimir L. and Kiselev, S. L. 2007. Phosphorylation of MAK-V protein kinase in mammalian cells. Doklady Biochemistry and Biophysics 412 (1) , pp. 37-39. 10.1134/S1607672907010115

Papachroni, Katerina K., Ninkina, Natalia, Papapanagiotou, Angeliki, Hadjigeorgiou, Georgios M., Xiromerisiou, Georgia, Papadimitriou, Alexandros, Kalofoutis, Anastasios and Buchman, Vladimir L. 2006. Autoantibodies to alpha-synuclein in inherited Parkinson's disease. Journal of Neurochemistry 101 (3) , pp. 749-756. 10.1111/j.1471-4159.2006.04365.x

Rzhepetskyy, Yu. A, Svinchuk, V. V., Mikhalap, S. V., Buchman, Vladimir L., Sidorenko, S. P. and Drobot, L. B. 2006. Identification of protein kinases possibly involved in adaptor protein Ruk/CIN85 post-translational modification [note]. Ukrain'skyi Biokhimichnyi Zhurnal 78 (6) , 150.

Mayevska, O., Shuvayeva, H., Igumentseva, N., Havrylov, S., Basaraba, O., Bobak, Y., Barska, M., Volod'ko, N., Baranska, K., Buchman, Vladimir and Drobot, L. 2006. Expression of adaptor protein Ruk/CIN85 isoforms in cell lines of various tissue origins and human melanoma. Experimental Oncology 28 (4) , pp. 275-281.

Ilnytska, O. M., Drel, V. R., Shuvayeva, H. Yu, Havrylov, S. V., Fedyshyn, Ya. Ya., Mayevska, O. M., Ihumentseva, N. I., Gout, I. T., Buchman, Vladimir L. and Drobot, L. B. 2005. Intra- and intermolecular interactions mediated by adaptor protein Ruk/CIN85/SETA. Biopolymers and Cell 21 (1) , pp. 48-54. 10.7124/bc.0006DB

Surgucheva, Irina, Ninkina, Natalia, Buchman, Vladimir L., Grasing, Kenneth and Surguchov, Andrei 2005. Protein aggregation in retinal cells and approaches to cell protection. Cellular and Molecular Neurobiology 25 (6) , pp. 1051-1066. 10.1007/s10571-005-8474-1

Papachroni, Katerina, Ninkina, Natalia, Wanless, Julia, Kalofoutis, Anastasios Th., Gnuchev, Nikolai V. and Buchman, Vladimir L. 2005. Peripheral sensory neurons survive in the absence of α- and γ-synucleins. Journal of Molecular Neuroscience 25 (2) , pp. 157-164. 10.1385/JMN:25:2:157

Simonova, O. B., Kulikova, D. A., Mertsalov, I. B., Umnova, O. N., Bashkirov, V. N., Buchman, Vladimir L. and Korochkin, L. I. 2005. Analysis of the overexpression of a newly found gene toothrin in Drosophila. Russian Journal of Genetics 41 (2) , pp. 138-143. 10.1007/s11177-005-0037-5

Mayevska, O. M., Bobak, Ya P., Shuvayeva, G. Yu., Igumentseva, I. M., Barska, M. L., Dul'tseva, N. A., Basaraba, O. I., Fedyshyn, Ya. Ya., Rzhepetsky, Yu. A., Mashtalir, N. B., Havrylov, S. V., Lyzogubov, V. V., Usenko, V. S., Buchman, Vladimir L. and Drobot, L. B. 2005. Monoclonal and polyclonal antibodies produced against adaptor/scaffold protein Ruk/CIN85/SETA: characterization and practical applications. Ukrain'skyi Biokhimichnyi Zhurnal 77 (2) , 211.

Borthwick, Emma B., Korobkob, Igor V., Luke, Courtney, Drelc, Victor R., Fedyshyn, Yaroslav Ya., Ninkina, Natalia, Drobot, Ludmila B. and Buchman, Vladimir 2004. Multiple Domains of Ruk/CIN85/SETA/CD2BP3 are Involved in Interaction with p85α Regulatory Subunit of PI 3-kinase. Journal of Molecular Biology 343 (4) , pp. 1135-1146. 10.1016/j.jmb.2004.08.075

Robertson, Darren C., Schmidt, Oliver, Ninkina, Natalia, Jones, Paul A., Sharkey, John and Buchman, Vladimir 2004. Developmental loss and resistance to MPTP toxicity of dopaminergic neurones in substantia nigra pars compacta of γ-synuclein, α-synuclein and double α/γ- synuclein null mutant mice. Journal of Neurochemistry 89 (5) , pp. 1126-1136. 10.1111/j.1471-4159.2004.02378.x

Saha, Anirban R., Hill, Josephine, Utton, Michelle A., Asuni, Ayodeji A., Ackerley, Steven, Grierson, Andrew J., Miller, Christopher C., Davies, Alun M., Buchman, Vladimir, Anderton, Brian H. and Hanger, Diane P. 2004. Parkinson's disease alpha-synuclein mutations exhibit defective axonal transport in cultured neurons. Journal of Cell Science 117 (Pt 7) , pp. 1017-1024. 10.1242/jcs.00967

Ruzov, Alexey S., Meehan, Richard, Kiselev, Sergey L., Buchman, Vladimir L., Korobko, Igor V. and Mertsalov, Ilya B. 2004. Cloning and developmental expression of MARK/Par-1/MELK-related protein kinase xMAK-V in Xenopus laevis. Development Genes and Evolution 214 (3) , pp. 139-143. 10.1007/s00427-004-0381-9

Ninkina, Natalia, Papachroni, Katerina, Robertson, Darren C., Schmidt, Oliver, Delaney, Liz, O'Neill, Francis, Court, Felipe, Rosenthal, Arnon, Fleetwood-Walker, Susan M., Davies, Alun M. and Buchman, Vladimir L. 2003. Neurons Expressing the Highest Levels of γ-Synuclein Are Unaffected by Targeted Inactivation of the Gene. Molecular and Cellular Biology 23 (22) , pp. 8233-8245. 10.1128/MCB.23.22.8233-8245.2003

Dev, Kumlesh K., Hofele, Katja, Barbieri, Samuel, Buchman, Vladmir L. and van der Putten, Herman 2003. Part II: α-synuclein and its molecular pathophysiological role in neurodegenerative disease. Neuropharmacology 45 (1) , pp. 14-44. 10.1016/S0028-3908(03)00140-0

Kit, Y. Y., Drel, V. R., Petriv, O.I., Kovalyova, V. A., Shuvaeva, G. Y., Palivoda, O. Y., Vovk, E. I., Bobak, Y. P., Rzeszowska-Wolny, J., Gout, I. T., Buchman, Vladimir L. and Drobot, L. B. 2003. Adaptor protein Ruk1 forms protein-protein complexes with endonuclease activity in HEK293 cells. Biochemistry (Moscow) 68 (7) , pp. 810-815.

Orel, V. R., Danyluk, O. Yu, Shuvajeva, G. Yu, Ihumenceva, N. I., Kit Yu, Ya, Gout, I. T., Buchman, Vladimir L. and Drobot, L. B. 2002. Subcellular localization of adapter protein Ruk, in HEK293 cells. Biopolymers and Cell 18 (4) , pp. 312-318. 10.7124/bc.000611

Verdier, Frédérique, Valovka, Taras, Zhyvoloup, Alexander, Drobot, Ludmila B., Buchman, Vladimir L., Waterfield, Mike and Gout, Ivan 2002. Ruk is ubiquitinated but not degraded by the proteasome. European Journal of Biochemistry 269 (14) , pp. 3402-3408. 10.1046/j.1432-1033.2002.03031.x

Buchman, Vladimir L., Luke, Courtney, Borthwick, Emma B., Gout, Ivan and Ninkina, Natalia 2002. Organization of the mouse Ruk locus and expression of isoforms in mouse tissues. Gene 295 (1) , pp. 13-17. 10.1016/S0378-1119(02)00821-1

Nabirochkina, Elena, Simonova, Olga B., Mertsalov, Ilja B., Kulikova, Dina A., Ladigina, Nadezshda G., Korochkin, Leonid I. and Buchman, Vladimir L. 2002. Expression pattern of dd4, a sole member of the d4 family of transcription factors in Drosophila melanogaster. Mechanisms of Development 114 (1-2) , pp. 119-123. 10.1016/S0925-4773(02)00035-7

Orike, Nina, Middleton, Gayle, Borthwick, Emma, Buchman, Vladimir L., Cowen, Timothy and Davies, Alun M. 2001. Role of PI 3-kinase, Akt and Bcl-2-related proteins in sustaining the survival of neurotrophic factor-independent adult sympathetic neurons. Journal of cell biology , pp. 995-1005. 10.1083/jcb.200101068

Alonzi, Tonino, Middleton, Gayle, Wyatt, Sean Lee, Buchman, Vladimir L., Ulrich, A. K. Betz, Muller, Werner, Musiani, Piero, Poli, Valeria and Davies, Alun M. 2001. Role of STAT3 and PI 3-Kinase/Akt in mediating the survival actions of cytokines on sensory neurons. Molecular and Cellular Neuroscience 18 (3) , pp. 270-282. 10.1006/mcne.2001.1018

Ninkina, Natalia, Mertsalov, Ilja B., Kulikova, Dina A., Alimova-Kost, Maria V., Simonova, Olga B., Korochkin, Leonid I., Kiselev, Sergey L. and Buchman, Vladimir L. 2001. Cerd4, third member of the d4 gene family: expression and organization of genomic locus. Mammalian Genome 12 (11) , pp. 862-866. 10.1007/s00335-001-3039-1

Saha, Anirban R., Ninkina, Natalia N., Hanger, Diane P., Anderton, Brian H., Davies, Alun M. and Buchman, Vladimir L. 2000. Induction of neuronal death by alpha-synuclein. European Journal of Neuroscience 12 (8) , pp. 3073-3077. 10.1046/j.1460-9568.2000.00210.x

Tiunova, A. A., Anokhin, K. V., Saha, A. R., Schmidt, O., Hanger, D. P., Anderton, B. H., Davies, A. M., Ninkina, Natalia and Buchman, Vladimir L. 2000. Chicken synucleins: cloning and expression in the developing embryo. Mechanisms of Development 99 (1-2) , pp. 195-198. 10.1016/S0925-4773(00)00484-6

Mertsalov, Ilja B., Kulikova, Dina A., Alimova-Kost, Maria V., Ninkina, Natalia N., Korochkin, Leonid I. and Buchman, Vladimir L. 2000. Structure and expression of two members of the d4 gene family in mouse. Mammalian Genome 11 (1) , pp. 72-74. 10.1007/s003350010014

Ninkina, Natalia and Buchman, Vladimir L. 2000. Synucleins: to have or not to have? Russian Journal of Genetics 36 (11) , pp. 1487-1491.

Gout, I., Middleton, G., Adu, J., Ninkina, Natalia, Drobot, L. B., Filonenko, V., Matsuka, G., Davies, A. M., Waterfield, M. and Buchman, Vladimir L. 2000. Negative regulation of PI 3-kinase by Ruk, a novel adaptor protein. Embo Journal 19 (15) , pp. 4015-4025.

Mertsalov, I. V., Kulikova, D. A., Ninkina, Natalia, Simonova, O. B., Buchman, Vladimir L. and Korochkin, Ll. 2000. Genomic organization of the mouse neuro-d4 gene. Russian Journal of Genetics 3 (36) , pp. 241-244.

This list was generated on Sat Oct 1 04:22:25 2022 BST.