Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Dunn, Steven M., Sami, Malkit, Boulter, Jonathan M., Jakobsen, Bent K. and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135
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T cell receptor engagement of peptide-major histocompatibility complex class I does not modify CD8 binding.
Molecular Immunology
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10.1016/j.molimm.2007.12.009
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Laugel, Bruno Frederic, Berg, Hugo A. van den, Gostick, Emma, Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Wooldridge, Linda, Boulter, Jonathan M, Milicic, Anita, Price, David ORCID: https://orcid.org/0000-0001-9416-2737 and Sewell, Andrew ORCID: https://orcid.org/0000-0003-3194-3135
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Different T cell receptor affinity thresholds and CD8 coreceptor dependence govern cytotxic T lymphocyte activation and tetramer properties.
The Journal of Biological Chemistry
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10.1074/jbc.M700976200
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Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Boulter, Jonathan M., Sami, Malkit, Vuidepot, Anne-lise, Glick, Meir, Gao, Feng, Bell, John I., Jakobsen, Bent K. and Gao, George F.
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Computational design and crystal structure of an enhanced affinity mutant human CD8 αα coreceptor.
Proteins: Structure, Function and Bioinformatics
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10.1002/prot.21176
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Wooldridge, Linda, Lissina, Anna, Vernazza, Jonathan, Gostick, Emma, Laugel, Bruno Frederic, Hutchinson, Sarah L., Mirza, Fareed, Dunbar, P. Rod, Boulter, Jonathan M., Glick, Meir, Cerundolo, Vincenzo, Berg, Hugo A. van den, Price, David ORCID: https://orcid.org/0000-0001-9416-2737 and Sewell, Andrew ORCID: https://orcid.org/0000-0003-3194-3135
2007.
Enhanced immunogenicity of CTL antigens through mutation of the CD8 binding MHC class I invariant region.
European Journal of Immunology
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10.1002/eji.200636765
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Gostick, Emma, Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Hutchinson, Sarah L., Wooldridge, Linda, Tafuro, Sabrina, Laugel, Bruno Frederic, Lissina, A., Oxenius, Annette, Boulter, Jonathan M., Price, David ORCID: https://orcid.org/0000-0001-9416-2737 and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135
2007.
Functional and biophysical characterization of an HLA-A*6801-restricted HIV-specific T cell receptor.
European Journal of Immunology
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, pp. 479-486.
10.1002/eji.200636243
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Boulter, Jonathan M., Schmitz, Nicole, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135, Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567, Bachmann, Martin F. and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004
2007.
Potent T cell agonism mediated by a very rapid TCR/pMHC interaction.
European Journal of Immunology
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10.1002/eji.200636743
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Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Gao, Feng, Watson, Neil I., Boulter, Jonathan M., Bell, John I., Sami, Malkit, Gao, George F. and Jakobsen, Bent K.
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Crystal structure of HLA-A*2402 complexed with a telomerase peptide.
European Journal of Immunology
36
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, pp. 170-179.
10.1002/eji.200535424
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| Boulter, Jonathan M, Vuidepot, A. L., Molloy, P. E. and Moysey, R. 2005. Directed evolution of human T-cell receptors with picomolar affinities by phage display. Nature Biotechnology 23 (3) , pp. 349-54. 10.1038/nbt1070 |
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Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Sami, Malkit, Lissin, Nikolai M., Gao, Feng, Bell, John I., Boulter, Jonathan M., Glick, Meir, Vuidepot, Anne-Lise, Jakobsen, Bent K. and Gao, George F.
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Crystallization and preliminary X-ray structural studies of a high-affinity CD8αα co-receptor to pMHC.
Acta Crystallographica Section F: Structural Biology and Crystallization Communications
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10.1107/S1744309105002988
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| Boulter, Jonathan M, Moskophidis, D., Nguyen, L. T. and Gronski, M. A. 2004. TCR affinity and negative regulation limit autoimmunity. Nature Medicine 10 (11) , pp. 1234-1239. 10.1038/nm1114 |
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| Boulter, Jonathan M, Baston, E., Glick, M. and Todorov, P. T. 2003. Stable, soluble T-cell receptor molecules for crystallization and therapeutics. Protein Engineering Design and Selection 16 (9) , pp. 701-711. 10.1093/protein/gzg087 |
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