Browse by Current Cardiff authors

Nicoli, Francesco, Cabral-Piccin, Mariela P., Papagno, Laura, Gallerani, Eleonora, Fusaro, Mathieu, Folcher, Victor, Dubois, Marion, Clave, Emmanuel, Vallet, Hélène, Frere, Justin J., Gostick, Emma, Llewellyn-Lacey, Sian, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Toubert, Antoine, Dupré, Loïc, Boddaert, Jacques, Caputo, Antonella, Gavioli, Riccardo and Appay, Victor 2022. Altered basal lipid metabolism underlies the functional impairment of naive CD8+ T cells in elderly humans. The Journal of Immunology 208 (3) , 562–570. 10.4049/jimmunol.2100194

Heim, Kathrin, Binder, Benedikt, Sagar, Wieland, Dominik, Hensel, Nina, Llewellyn-Lacey, Sian, Gostick, Emma, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Emmerich, Florian, Vingerhoet, Hildegard, Kraft, Anke R M, Cornberg, Markus, Boettler, Tobias, Neumann-Haefelin, Christoph, Zehn, Dietmar, Bengsch, Bertram, Hofmann, Maike and Thimme, Robert 2021. TOX defines the degree of CD8+ T cell dysfunction in distinct phases of chronic HBV infection. Gut 70 , pp. 1550-1560. 10.1136/gutjnl-2020-322404

Passaes, Caroline, Millet, Antoine, Madelain, Vincent, Monceaux, Valérie, David, Annie, Versmisse, Pierre, Sylla, Naya, Gostick, Emma, Llewellyn-Lacey, Sian, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Blancher, Antoine, Dereuddre-Bosquet, Nathalie, Desjardins, Delphine, Pancino, Gianfranco, Le Grand, Roger, Lambotte, Olivier, Müller-Trutwin, Michaela, Rouzioux, Christine, Guedj, Jérémie, Avettand-Fenoel, Véronique, Vaslin, Bruno and Sáez-Cirión, Asier 2020. Optimal maturation of the SIV-Specific CD8+ T cell response after primary infection is associated with natural control of SIV: ANRS SIC study. Cell Reports 32 (12) , 108174. 10.1016/j.celrep.2020.108174

Papagno, Laura, Kuse, Nozomi, Lissina, Anna, Gostick, Emma, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Appay, Victor and Nicoli, Francesco 2020. The TLR9 ligand CpG ODN 2006 is a poor adjuvant for the induction of de novo CD8+ T-cell responses in vitro. Scientific Reports 10 (1) , 11620. 10.1038/s41598-020-67704-0

Nguyen, Son, Deleage, Claire, Darko, Samuel, Ransier, Amy, Truong, Duc P., Agarwal, Divyansh, Japp, Alberto Sada, Wu, Vincent H., Kuri-Cervantes, Leticia, Abdel-Mohsen, Mohamed, Del Rio Estrada, Perla M., Ablanedo-Terrazas, Yuria, Gostick, Emma, Hoxie, James A., Zhang, Nancy R., Naji, Ali, Reyes-Terán, Gustavo, Estes, Jacob D., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Douek, Daniel C., Deeks, Steven G., Buggert, Marcus and Betts, Michael R. 2019. Elite control of HIV is associated with distinct functional and transcriptional signatures in lymphoid tissue CD8+ T cells. Science Translational Medicine 11 (523) , eaax4077. 10.1126/scitranslmed.aax4077

Kemming, Janine, Reeves, Emma, Nitschke, Katja, Widmeier, Vanessa, Emmerich, Florian, Hermle, Tobias, Gostick, Emma, Walker, Andreas, Timm, Jörg, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Hofmann, Maike, Thimme, Robert, James, Edward and Neumann-Haefelin, Christoph 2019. ERAP1 allotypes shape the epitope repertoire of virus-specific CD8+ T cell responses in acute hepatitis C virus infection. Journal of Hepatology 70 (6) , pp. 1072-1081. 10.1016/j.jhep.2019.01.034

Dockree, Tamsin, Holland, Christopher J., Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, McLaren, James Edward ORCID: https://orcid.org/0000-0002-7021-5934, Van Den Berg, Hugo A., Gostick, Emma, Llewellyn-Lacey, Sian, Man, Stephen Tzekwung ORCID: https://orcid.org/0000-0001-9103-1686, Bailey, Mick, Burrows, Scott, Price, David ORCID: https://orcid.org/0000-0001-9416-2737 and Wooldridge, Linda 2017. CD8+ T-cell specificity is compromised at a defined MHCI/CD8 affinity threshold. Immunology and Cell Biology 95 (1) , pp. 68-76. 10.1038/icb.2016.85

Flecken, Tobias, Schmidt, Nathalie, Hild, Sandra, Gostick, Emma, Drognitz, Oliver, Zeiser, Robert, Schemmer, Peter, Bruns, Helge, Eiermann, Thomas, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Blum, Hubert E., Neumann-Haefelin, Christoph and Thimme, Robert 2014. Immunodominance and functional alterations of tumor-associated antigen-specific CD8+T-cell responses in hepatocellular carcinoma. Hepatology 59 (4) , pp. 1415-1426. 10.1002/hep.26731

O'Connor, G.eraldine M., Vivian, Julian P., Widjaja, Jacqueline M., Bridgeman, John S., Gostick, Emma, Lafont, Bernard A. P., Anderson, Stephen K., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Brooks, Andrew G., Rossjohn, Jamie ORCID: https://orcid.org/0000-0002-2020-7522 and McVicar, Daniel W. 2014. Mutational and structural analysis of KIR3DL1 reveals a lineage-defining allotypic dimorphism that impacts both HLA and peptide sensitivity. Journal of Immunology 192 (6) , pp. 2875-2884. 10.4049/jimmunol.1303142

Roux, Antoine, Mourin, Gisèle, Fastenackels, Solène, Almeida, Jorge R., Iglesias, Maria Candela, Boyd, Anders, Gostick, Emma, Larsen, Martin, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Sacre, Karim, Douek, Daniel C., Autran, Brigitte, Picard, Clément, Miranda, Sandra de, Sauce, Delphine, Stern, Marc and Appay, Victor 2013. CMV driven CD8+ T-cell activation is associated with acute rejection in lung transplantation. Clinical Immunology 148 (1) , pp. 16-26. 10.1016/j.clim.2013.03.012

Quinn, K. M., Da Costa, A., Yamamoto, A., Berry, D., Lindsay, R. W. B., Darrah, P. A., Wang, L., Cheng, C., Kong, W.-P., Gall, J. G. D., Nicosia, A., Folgori, A., Colloca, S., Cortese, R., Gostick, Emma, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Gomez, C. E., Esteban, M., Wyatt, L. S., Moss, B., Morgan, C., Roederer, M., Bailer, R. T., Nabel, G. J., Koup, R. A. and Seder, R. A. 2013. Comparative analysis of the magnitude, quality, phenotype, and protective capacity of simian immunodeficiency virus gag-specific CD8+ T cells following human-, simian-, and chimpanzee-derived recombinant adenoviral vector immunization. The Journal of Immunology 190 (6) , pp. 2720-2735. 10.4049/jimmunol.1202861

Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Hashimoto, Masao, Iglesias, Maria Candela, Wilmann, Pascal G., McLaren, James Edward ORCID: https://orcid.org/0000-0002-7021-5934, Gras, Stéphanie, Chikata, Takayuki, Kuse, Nozomi, Fastenackels, Solène, Gostick, Emma, Bridgeman, John S., Venturi, Vanessa, Arkoub, Zaïna Aït, Agut, Henri, van Bockel, David J., Almeida, Jorge R., Douek, Daniel C., Meyer, Laurence, Venet, Alain, Takiguchi, Masafumi, Rossjohn, Jamie ORCID: https://orcid.org/0000-0002-2020-7522, Price, David ORCID: https://orcid.org/0000-0001-9416-2737 and Appay, Victor 2013. A molecular basis for the control of preimmune escape variants by HIV-specific CD8+ T cells. Immunity 38 (3) , pp. 425-436. 10.1016/j.immuni.2012.11.021

Iglesias, Maria Candela, Briceno, Olivia, Gostick, Emma, Moris, Arnaud, Meaudre, Céline, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Ungeheuer, Marie-Noëlle, Saez-Cirion, Asier, Mallone, Roberto and Appay, Victor 2013. Immunodominance of HLA-B27-restricted HIV KK10-specific CD8+ T-cells is not related to naïve precursor frequency [Letter]. Immunology Letters 149 (1-2) , pp. 119-122. 10.1016/j.imlet.2012.10.002

Vavassori, Stefano, Kumar, Anil, Wan, Gan Siok, Ramanjaneyulu, Gundimeda S., Cavallari, Marco, El Daker, Sary, Beddoe, Travis, Theodossis, Alex, Williams, Neal K., Gostick, Emma, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Soudamini, Dinish U., Voon, Kong Kien, Olivo, Malini, Rossjohn, Jamie ORCID: https://orcid.org/0000-0002-2020-7522, Mori, Lucia and De Libero, Gennaro 2013. Butyrophilin 3A1 binds phosphorylated antigens and stimulates human γδ T cells. Nature Immunology 14 (9) , pp. 908-916. 10.1038/ni.2665

Budimir, Natalija, de Haan, Aalzen, Meijerhof, Tjarko, Gostick, Emma, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Huckriede, Anke and Wilschut, Jan 2013. Heterosubtypic cross-protection induced by whole inactivated influenza virus vaccine in mice: influence of the route of vaccine administration. Influenza and Other Respiratory Viruses 7 (6) , pp. 1202-1209. 10.1111/irv.12142

Ekeruche, Julia, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Edwards, Emily S. J. ORCID: https://orcid.org/0000-0002-0240-4370, Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Miles, John James, Matthews, Katherine K., Fuller, Anna, Lloyd, Katy A., Madura, Florian, Dolton, Garry Michael, Pentier, Johanne, Lissina, Anna, Gostick, Emma, Baxter, Tiffany K., Baker, Brian M., Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Wooldridge, Linda and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 2012. T-cell receptor-optimized peptide skewing of the T-cell repertoire can enhance antigen targeting. Journal of Biological Chemistry 287 (44) , pp. 37269-37281. 10.1074/jbc.M112.386409

Budde, Melisa L., Greene, Justin M., Chin, Emily N., Ericsen, Adam J., Scarlotta, Matthew, Cain, Brian T., Pham, Ngoc H., Becker, Ericka A., Harris, Max, Weinfurter, Jason T., O'Connor, Shelby L., Piatak Jr., Michael, Lifson, Jeffrey D., Gostick, Emma, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Friedrich, Thomas C. and O'Connor, David H. 2012. Specific CD8+ T cell responses correlate with control of simian immunodeficiency virus replication in Mauritian cynomolgus macaques. Journal of Virology 86 (14) , pp. 7596-7604. 10.1128/JVI.00716-12

Johnson, Matthew J., Petrovas, Constantinos, Yamamoto, Takuya, Lindsay, Ross W. B., Lore, Karin, Gall, Jason G. D., Gostick, Emma, Lefebvre, François, Cameron, Mark J., Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Haddad, Elias, Sekaly, Rafick-Pierre, Seder, Robert A. and Koup, Richard A. 2012. Type I IFN induced by adenovirus serotypes 28 and 35 has multiple effects on T cell immunogenicity. The Journal of Immunology 188 (12) , pp. 6109-6118. 10.4049/jimmunol.1103717

Bulek, Anna Marta, Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Skowera, Ania, Dolton, Garry Michael, Gras, Stephanie, Madura, Florian, Fuller, Anna, Miles, John James, Gostick, Emma, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Drijfhout, Jan W., Knight, Robin R., Huang, Guo C., Lissin, Nikolai, Molloy, Peter E., Wooldridge, Linda, Jakobsen, Bent K., Rossjohn, Jamie, Peakman, Mark, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369 and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 2012. Structural basis for the killing of human beta cells by CD8+ T cells in type 1 diabetes. Nature Immunology 13 (3) , pp. 283-289. 10.1038/ni.2206

Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Gallagher, Kathleen, Lemercier, Brigitte, Holland, Christopher J., Junaid, Sayed, Hindley, James Phillip, Wynn, Katherine Kay, Gostick, Emma, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135, Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004, Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Gougeon, Marie-Lise and Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567 2012. Modification of the carboxy-terminal flanking region of a universal influenza epitope alters CD4+ T-cell repertoire selection. Nature Communications 3 , 665. 10.1038/ncomms1665

Budimir, Natalija, Huckriede, Anke, Meijerhof, Tjarko, Boon, Louis, Gostick, Emma, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Wilschut, Jan and de Haan, Aalzen 2012. Induction of heterosubtypic cross-protection against influenza by a whole inactivated virus vaccine: the role of viral membrane fusion activity. PLoS ONE 7 (1) , e30898. 10.1371/journal.pone.0030898

Maloveste, Sebastien M., Chen, Dan, Gostick, Emma, Vivian, Julian P., Plishka, Ronald J., Iyengar, Ranjini, Kruthers, Robin L., Buckler-White, Alicia, Brooks, Andrew G., Rossjohn, Jamie, Price, David ORCID: https://orcid.org/0000-0001-9416-2737 and Lafont, Bernard A. P. 2012. Degenerate recognition of MHC class I molecules with Bw4 and Bw6 motifs by a killer cell Ig-like receptor 3DL expressed by macaque NK cells. The Journal of Immunology 189 (9) , pp. 4338-4348. 10.4049/jimmunol.1201360

Gattinoni, Luca, Lugli, Enrico, Ji, Yun, Pos, Zoltan, Paulos, Chrystal M., Quigley, Maire F., Almeida, Jorge R., Gostick, Emma, Yu, Zhiya, Carpenito, Carmine, Wang, Ena, Douek, Daniel C., Price, David ORCID: https://orcid.org/0000-0001-9416-2737, June, Carl H., Marincola, Francesco M., Roederer, Mario and Restifo, Nicholas P. 2011. A human memory T cell subset with stem cell-like properties. Nature Medicine 17 (10) , pp. 1290-1297. 10.1038/nm.2446

Haney, Danielle, Quigley, Máire F., Asher, Tedi E., Ambrozak, David R., Gostick, Emma, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Douek, Daniel C. and Betts, Michael R. 2011. Isolation of viable antigen-specific CD8+ T cells based on membrane-bound tumor necrosis factor (TNF)-α expression. Journal of Immunological Methods 369 (1-2) , pp. 33-41. 10.1016/j.jim.2011.04.003

Kreutzman, A., Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Koechel, C., Gostick, Emma, Ekblom, M., Stenke, L., Melo, T., Einsele, H., Porkka, K., Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Mustjoki, S. and Seggewiss, R. 2011. Expansion of highly differentiated CD8+ T-cells or NK-cells in patients treated with dasatinib is associated with cytomegalovirus reactivation. Leukemia 25 (10) , pp. 1587-1597. 10.1038/leu.2011.135

Nagai, Kozo, Ochi, Toshiki, Fujiwara, Hiroshi, An, Jun, Shirakata, Toshiaki, Mineno, Junichi, Kuzushima, Kiyotaka, Shiku, Hiroshi, Melenhorst, J. Joseph, Gostick, Emma, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Ishii, Eiichi and Yasukawa, Masaki 2011. Aurora kinase A-specific T-cell receptor gene transfer redirects T lymphocytes to display effective antileukemia reactivity. Blood 119 (2) , pp. 368-376. 10.1182/blood-2011-06-360354

Ruckwardt, Tracy J., Malloy, Allison M. W., Gostick, Emma, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Dash, Pradyot, McClaen, Jennifer L., Thonas, Paul G. and Graham, Barney S. 2011. Neonatal cd8 t-cell hierarchy is distinct from adults and is influenced by intrinsic t cell properties in respiratory syncytial virus infected mice. PLoS Pathogens 7 (12) , e1002377. 10.1371/journal.ppat.1002377

Falkenburg, Willem J. J., Melenhorst, J. Joseph, van de Meent, Marian, Kester, Michel, Hombrink, Pleun, Heemskerk, Mirjam H. M., Hagedoorn, Renate S., Gostick, Emma, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Falkenburg, J. H. Frederik, Barrett, A. John and Jedema, Inge 2011. Allogeneic HLA-A*02-restricted WT1-specific T cells from mismatched donors are highly reactive but show off-target promiscuity. The Journal of Immunology 187 (5) , pp. 2824-2833. 10.4049/jimmunol.1100852

Vojnov, Lara, Martins, Mauricio A., Almeida, Jorge R., Ende, Zachary, Rakasz, Eva G., Reynolds, Matthew R., Leon, Enrique J., Weisgrau, Kim L., Burwitz, Benjamin J., Folkvord, Joy M., Veloso de Santana, Marlon G., Costa Neves, Patrícia C., Connick, Elizabeth, Skinner, Pamela J., Gostick, Emma, O'Connor, David H., Wilson, Nancy A., Bonaldo, Myrna C., Galler, Ricardo, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Douek, Danny C. and Watkins, David I. 2011. GagCM9-specific CD8+ T cells expressing limited public TCR clonotypes do not suppress SIV replication in vivo. PLoS ONE 6 (8) , e23515. 10.1371/journal.pone.0023515

Iglesias, Maria Candela, Almeida, Jorge R., Fastenackels, Solene, van Bockel, David J., Hashimoto, Masao, Venturi, Vanessa, Gostick, Emma, Urrutia, Alejandra, Wooldridge, Linda, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Gras, Stephanie, Wilmann, Pascal G., Autran, Brigitte, Moris, Arnaud, Rossjohn, Jamie, Davenport, Miles P., Takiguchi, Masafumi, Brander, Christian, Douek, Daniel C., Kelleher, Anthony D., Price, David ORCID: https://orcid.org/0000-0001-9416-2737 and Appay, Victor 2011. Escape from highly effective public CD8+ T-cell clonotypes by HIV. Blood 118 (8) , pp. 2138-2149. 10.1182/blood-2011-01-328781

Yamamoto, Takuya, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Casazza, Joseph P., Ferrari, Guido, Nason, Martha, Chattopadhyay, Pratip K., Roederer, Mario, Gostick, Emma, Katsikis, Peter D., Douek, Daniel C., Haubrich, Richard, Petrovas, Constantinos and Koup, Richard A. 2011. Surface expression patterns of negative regulatory molecules identify determinants of virus-specific CD8+ T-cell exhaustion in HIV infection. Blood 117 (18) , pp. 4805-4815. 10.1182/blood-2010-11-317297

Sloand, Elaine M., Melenhorst, J. Joseph, Tucker, Zachary C. G., Pfannes, Loretta, Brenchley, Jason M., Yong, Agnes, Visconte, Valeria, Wu, Colin, Gostick, Emma, Scheinberg, Phillip, Olnes, Matthew J., Douek, Daniel C., Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Barrett, A. John and Young, Neal S. 2011. T-cell immune responses to Wilms tumor 1 protein in myelodysplasia responsive to immunosuppressive therapy. Blood 117 (9) , pp. 2691-2699. 10.1182/blood-2010-04-277921

Humphreys, Ian R. ORCID: https://orcid.org/0000-0002-9512-5337, Lee, Seung-Woo, Jones, Morgan, Loewendorf, Andrea, Gostick, Emma, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Benedict, Chris A., Ware, Carl F. and Croft, Michael 2010. Biphasic role of 4-1BB in the regulation of mouse cytomegalovirus-specific CD8+ T cells. European Journal of Immunology 40 (10) , pp. 2762-2768. 10.1002/eji.200940256

Jones, Morgan, Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Wynn, Katherine, Stacey, Maria A., Quigley, Maire F., Gostick, Emma, Price, David ORCID: https://orcid.org/0000-0001-9416-2737 and Humphreys, Ian R. ORCID: https://orcid.org/0000-0002-9512-5337 2010. IL-10 restricts memory T cell inflation during cytomegalovirus infection. The Journal of Immunology 185 (6) , pp. 3583-3592. 10.4049/jimmunol.1001535

Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Edwards, Emily ORCID: https://orcid.org/0000-0002-0240-4370, Wynn, Katherine, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Miles, John James, Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Ekeruche, Julia, Gostick, Emma, Adams, Katherine J., Skowera, Ania, Peakman, Mark, Wooldridge, Linda, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737 and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 2010. Modification of MHC anchor residues generates heteroclitic peptides that alter TCR binding and T cell recognition. The Journal of Immunology 185 (4) , pp. 2600-2610. 10.4049/jimmunol.1000629

Miles, John James, Bulek, Anna Marta, Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Gostick, Emma, Schauenburg, Andrea J. A., Dolton, Garry Michael, Venturi, Vanessa, Davenport, Miles P., Tan, Mai Ping, Burrows, Scott R., Wooldridge, Linda, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369 and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 2010. Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr virus infection. PLoS Pathogens 6 (11) , e1001198. 10.1371/journal.ppat.1001198

Wooldridge, Linda, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Lissina, Anna, Edwards, Emily ORCID: https://orcid.org/0000-0002-0240-4370, Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Ekeruche, Julia, Hewitt, R. E., Laugel, Bruno Frederic, Gostick, Emma, Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Debets, R., Berrevoets, C., Miles, John James, Burrows, S. R., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737 and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 2010. MHC Class I molecules with superenhanced CD8 binding properties bypass the requirement for cognate TCR recognition and nonspecifically activate CTLs. Journal of Immunology 184 (7) , pp. 3357-3366. 10.4049/jimmunol.0902398

Van Tendeloo, V. F., Van de Velde, A., Van Driessche, A., Cools, N., Anguille, S., Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Gostick, Emma, Vermeulen, K., Pieters, K., Nijs, G., Stein, B., Smits, E. L., Schroyens, W. A., Gadisseur, A. P., Vrelust, I., Jorens, P. G., Goossens, H., de Vries, I. J., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Oji, Y., Oka, Y., Sugiyama, H. and Berneman, Z. N. 2010. Induction of complete and molecular remissions in acute myeloid leukemia by Wilms' tumor 1 antigen-targeted dendritic cell vaccination. Proceedings of the National Academy of Sciences of the United States of America 107 (31) , pp. 13824-13829. 10.1073/pnas.1008051107

Giannopoulos, K., Dmoszynska, A., Kowal, M., Rolinski, J., Gostick, Emma, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Greiner, J., Rojewski, M., Stilgenbauer, S., Döhner, H. and Schmitt, M. 2010. Peptide vaccination elicits leukemia-associated antigen-specific cytotoxic CD8+ T-cell responses in patients with chronic lymphocytic leukemia. Leukemia 24 (4) , pp. 798-805. 10.1038/leu.2010.29

Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Asher, Tedi E., Wilson, Nancy A., Nason, Martha C., Brenchley, Jason M., Metzler, Ian S., Venturi, Vanessa, Gostick, Emma, Chattopadhyay, Pratip K., Roederer, Mario, Davenport, Miles P., Watkins, David I. and Douek, Daniel C. 2009. Public clonotype usage identifies protective Gag-specific CD8+ T cell responses in SIV infection. Journal of Experimental Medicine 206 (4) , pp. 923-936. 10.1084/jem.20081127

Melenhorst, J. Joseph, Scheinberg, Phillip, Chattopadhyay, Pratip K., Gostick, Emma, Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Roederer, Mario, Hensel, Nancy F., Douek, Daniel C., Barrett, A. John and Price, David ORCID: https://orcid.org/0000-0001-9416-2737 2009. High avidity myeloid leukemia-associated antigen-specific CD8+ T cells preferentially reside in the bone marrow. Blood 113 (10) , pp. 2238-2244. 10.1182/blood-2008-04-151969

Lissina, Anna, Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Skowera, Ania, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Edwards, Emily ORCID: https://orcid.org/0000-0002-0240-4370, Seggewiss, Ruth, van den Berg, Hugo A., Gostick, Emma, Gallagher, Kathleen, Jones, Emma, Melenhorst, J. Joseph, Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567, Peakman, Mark, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 and Wooldridge, Linda 2009. Protein kinase inhibitors substantially improve the physical detection of T-cells with peptide-MHC tetramers. Journal of Immunological Methods 340 (1) , pp. 11-24. 10.1016/j.jim.2008.09.014

Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Yuan, Fang, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Miles, John James, Gostick, Emma, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Gao, George F., Jakobsen, Bent K. and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 2009. Germ line-governed recognition of a cancer epitope by an immunodominant human T-cell receptor. Journal of Biological Chemistry 284 (40) , 27281-27289. 10.1074/jbc.M109.022509

Nakamoto, Nobuhiro, Cho, Hyosun, Shaked, Abraham, Olthoff, Kim, Valiga, Mary E., Kaminski, Mary, Gostick, Emma, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Freeman, Gordon J., Wherry, E. John and Chang, Kyong-Mi 2009. Synergistic reversal of intrahepatic hcv-specific cd8 t cell exhaustion by combined pd-1/ctla-4 blockade. PLoS Pathogens 5 (2) , e1000313. 10.1371/journal.ppat.1000313

Geldmacher, Christof, Metzler, Ian S., Tovanabutra, Sodsai, Asher, Tedi E., Gostick, Emma, Ambrozak, David R., Petrovas, Constantinos, Schuetz, Alexandra, Ngwenyama, Njabulo, Kijak, Gustavo, Maboko, Leonard, Hoelscher, Michael, McCutchan, Francine, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Douek, Daniel C. and Koup, Richard A. 2009. Minor viral and host genetic polymorphisms can dramatically impact the biologic outcome of an epitope-specific CD8 T-cell response. Blood 114 (8) , pp. 1553-1562. 10.1182/blood-2009-02-206193

Chattopadhyay, Pratip K., Betts, Michael R., Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Gostick, Emma, Horton, Helen, Roederer, Mario and De Rosa, Stephen C. 2009. The cytolytic enzymes granyzme A, granzyme B, and perforin: expression patterns, cell distribution, and their relationship to cell maturity and bright CD57 expression. Journal of Leukocyte Biology 85 (1) , pp. 88-97. 10.1189/jlb.0208107

Melenhorst, J. Joseph, Scheinberg, Phillip, Chattopadhyay, Pratip K., Lissina, Anna, Gostick, Emma, Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Wooldridge, Linda, van den Berg, Hugo A., Bornstein, Ethan, Hensel, Nancy F., Douek, Daniel C., Roederer, Mario, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135, Barrett, A. John and Price, David ORCID: https://orcid.org/0000-0001-9416-2737 2008. Detection of low avidity CD8+ T cell populations with coreceptor-enhanced peptide-major histocompatibility complex class I tetramers. Journal of Immunological Methods 338 (1-2) , pp. 31-39. 10.1016/j.jim.2008.07.008

Mielke, Stephan, Nunes, Raquel, Rezvani, Katayoun, Fellowes, Vicki S., Venne, Annie, Solomon, Scott R., Fan, Yong, Gostick, Emma, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Scotto, Christian, Read, Elizabeth J. and Barrett, A. John 2008. A clinical-scale selective allodepletion approach for the treatment of HLA-mismatched and matched donor-recipient pairs using expanded T lymphocytes as antigen-presenting cells and a TH9402-based photodepletion technique. Blood 111 (8) , pp. 4392-4402. 10.1182/blood-2007-08-104471

Nakamoto, Nobuhiro, Kaplan, David E., Coleclough, Jennifer, Li, Yun, Valiga, Mary E., Kaminski, Mary, Shaked, Abraham, Olthoff, Kim, Gostick, Emma, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Freeman, Gordon J., Wherry, E. John and Chang, Kyong-Mi 2008. Functional restoration of HCV-specific CD8 T Cells by PD-1 blockade is defined by PD-1 expression and compartmentalization. Gastroenterology 134 (7) , pp. 1927-1937. 10.1053/j.gastro.2008.02.033

Reynolds, M. R., Weiler, A. M., Weisgrau, K. L., Piaskowski, S. M., Furlott, J. R., Weinfurter, J. T., Kaizu, M., Soma, T., Leon, E. J., MacNair, C., Leaman, D. P., Zwick, M. B., Gostick, Emma, Musani, S. K., Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Friedrich, T. C., Rakasz, E. G., Wilson, N. A., McDermott, A. B., Boyle, R., Allison, D. B., Burton, D. R., Koff, W. C. and Watkins, D. I. 2008. Macaques vaccinated with live-attenuated SIV control replication of heterologous virus. Journal of Experimental Medicine 205 (11) , pp. 2537-2550. 10.1084/jem.20081524

Brenchley, J. M., Knox, K. S., Asher, A. I., Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Kohli, L. M., Gostick, Emma, Hill, B. J., Hage, C. A., Brahmi, Z., Khoruts, A., Twigg, H. L., Schacker, T. W. and Douek, D. C. 2008. High frequencies of polyfunctional HIV-specific T cells are associated with preservation of mucosal CD4 T cells in bronchoalveolar lavage. Mucosal Immunology 1 (1) , pp. 49-58. 10.1038/mi.2007.5

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Weichsel, Ralf, Dix, Carolin, Wooldridge, Linda, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Fenton-May, Angharad, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135, Zezula, Josef, Greiner, Elizabeth, Gostick, Emma, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Einsele, Hermann and Seggewiss, Ruth 2008. Profound inhibition of antigen-specific T-cell effector functions by dasatinib. Clinical Cancer Research 14 (8) , pp. 2484-2491. 10.1158/1078-0432.CCR-07-4393

Laugel, Bruno Frederic, Berg, Hugo A. van den, Gostick, Emma, Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Wooldridge, Linda, Boulter, Jonathan M, Milicic, Anita, Price, David ORCID: https://orcid.org/0000-0001-9416-2737 and Sewell, Andrew ORCID: https://orcid.org/0000-0003-3194-3135 2007. Different T cell receptor affinity thresholds and CD8 coreceptor dependence govern cytotxic T lymphocyte activation and tetramer properties. The Journal of Biological Chemistry 282 (33) , pp. 23799-22810. 10.1074/jbc.M700976200

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Wooldridge, Linda, Lissina, Anna, Vernazza, Jonathan, Gostick, Emma, Laugel, Bruno Frederic, Hutchinson, Sarah L., Mirza, Fareed, Dunbar, P. Rod, Boulter, Jonathan M., Glick, Meir, Cerundolo, Vincenzo, Berg, Hugo A. van den, Price, David ORCID: https://orcid.org/0000-0001-9416-2737 and Sewell, Andrew ORCID: https://orcid.org/0000-0003-3194-3135 2007. Enhanced immunogenicity of CTL antigens through mutation of the CD8 binding MHC class I invariant region. European Journal of Immunology 37 (5) , pp. 1323-1333. 10.1002/eji.200636765

Chattopadhyay, Pratip K., Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Harper, Theresa F., Betts, Michael R., Yu, Joanne, Gostick, Emma, Perfetto, Stephen P., Goepfert, Paul, Koup, Richard A., De Rosa, Stephen C., Bruchez, Marcel P. and Roederer, Mario 2006. Quantum dot semiconductor nanocrystals for immunophenotyping by polychomatic flow cytometry. Nature Medicine 12 (8) , pp. 972-7. 10.1038/nm1371

Wooldridge, Linda, Scriba, Thomas J., Milicic, Anita, Laugel, Bruno Frederic, Gostick, Emma, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Phillips, Rodney E. and Sewell, Andrew ORCID: https://orcid.org/0000-0003-3194-3135 2006. Anti-coreceptor antibodies profoundly affect staining with peptide-MHC class I and class II tetramers. European Journal of Immunology 36 (7) , pp. 1847-1855. 10.1002/eji.200635886

Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Brenchley, Jason M., Ruff, Laura E., Betts, Michael R., Hill, Brenna J., Roederer, Mario, Koup, Richard A., Migueles, Steven A., Gostick, Emma, Wooldridge, Linda, Sewell, Andrew ORCID: https://orcid.org/0000-0003-3194-3135, Connors, Mark and Douek, Daniel C. 2005. Avidity for antigen shapes clonal dominance in CD8+ T cell populations specific for persistent DNA viruses. Journal of Experimental Medicine 202 (10) , pp. 1349-61. 10.1084/jem.20051357

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