ORCA
Online Research @ Cardiff
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Moon, Owen R., Newman, Andrew C., Alanazi, Abdullah S., Wehenkel, Sophie C., Gawel-Bęben, Katarzyna, Ivetic, Aleksandar, Price, David A.  ORCID: https://orcid.org/0000-0001-9416-2737, Knauper, Vera ORCID: https://orcid.org/0000-0002-3965-9924 and Ager, Ann ORCID: https://orcid.org/0000-0002-5763-8908
2025.
TCR activation stimulates regulated intramembrane proteolysis of L-selectin by presenilin 1 and localized proteasomal degradation of the cytoplasmic tail.
Journal of Biological Chemistry
301
(8)
, 110473.
10.1016/j.jbc.2025.110473
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Mohammed, Rebar N., Wehenkel, Sophie C., Galkina, Elena V., Yates, Emma-Kate, Preece, Graham, Newman, Andrew, Watson, H. Angharad, Ohme, Julia, Bridgeman, John S., Durairaj, Ruban R. P., Moon, Owen R., Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Miners, Kelly L., Dolton, Garry, Troeberg, Linda, Kashiwagi, Masahide, Murphy, Gillian, Nagase, Hideaki, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Matthews, R. James, Knauper, Vera ORCID: https://orcid.org/0000-0002-3965-9924 and Ager, Ann ORCID: https://orcid.org/0000-0002-5763-8908
2019.
ADAM17-dependent proteolysis of L-selectin promotes early clonal expansion of cytotoxic T cells.
Scientific Reports
9
, 5487.
10.1038/s41598-019-41811-z
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Wehenkel, Sophie
2015.
Manipulating T lymphocyte homing and activation for cancer immunotherapy.
PhD Thesis,
Cardiff University.
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