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Giannoni, Eric, Sanchez, Guillem Sanchez, Verdebout, Isoline, Papadopoulou, Maria, Rezwani, Moosa, Ahmed, Raya, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Miners, Kelly L., McLaren, James E. ORCID: https://orcid.org/0000-0002-7021-5934, Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Eberl, Matthias ORCID: https://orcid.org/0000-0002-9390-5348, Study, Swiss Pediatric Sepsis, Agyeman, Philipp K.A., Schlapbach, Luregn and Vermijlen, David 2024. Sepsis shapes the human γδ TCR repertoire in an age- and pathogen-dependent manner. European Journal of Immunology 54 (10) , 2451190. 10.1002/eji.202451190 |
Baillie, Kirsten, Davies, Helen E., Keat, Samuel B. K., Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Miners, Kelly L., Jones, Samantha A., Mellou, Ermioni, Toonen, Erik J. M., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Zelek, Wioleta M. 2024. Complement dysregulation is a prevalent and therapeutically amenable feature of long COVID. Med 5 (3) , pp. 239-253. 10.1016/j.medj.2024.01.011 |
Roger, Laureline, Miners, Kelly L., Leonard, Louise, Grimstead, Julia W., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Baird, Duncan M. ORCID: https://orcid.org/0000-0001-8408-5467 and Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938 2023. T cell memory revisited using single telomere length analysis. Frontiers in Immunology 14 , 1100535. 10.3389/fimmu.2023.1100535 |
Rubina, Anzelika, Patel, Mihil, Nightingale, Katie, Potts, Martin, Fielding, Ceri A. ORCID: https://orcid.org/0000-0002-5817-3153, Kollnberger, Simon, Lau, Betty, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Miners, Kelly L., Nichols, Jenna, Nobre, Luis, Roberts, Dawn, Trinca, Terrence M., Twohig, Jason P., Vlahava, Virginia-Maria, Davison, Andrew J., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Tomasec, Peter, Wilkinson, Gavin W. G., Weekes, Michael P., Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182 and Wang, Eddie C. Y. ORCID: https://orcid.org/0000-0002-2243-4964 2023. ADAM17 targeting by human cytomegalovirus remodels the cell surface proteome to simultaneously regulate multiple immune pathways. Proceedings of the National Academy of Sciences 120 (33) , e2303155120. 10.1073/pnas.2303155120 |
Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Miners, Kelly L, Marsden, Morgan, Chapman, Lucy, Cardus Figueras, Anna, Scott, Jake, Andrews, Robert, Clare, Simon, Kriukova, Valeriia V, Lupyr, Ksenia R, Britanova, Olga V, Withers, David R, Jones, Simon A ORCID: https://orcid.org/0000-0001-7297-9711, Chudakov, Dmitriy M, Price, David A ORCID: https://orcid.org/0000-0001-9416-2737 and Humphreys, Ian R ORCID: https://orcid.org/0000-0002-9512-5337 2023. Inhibitory IL-10-producing CD4+ T cells are T-bet-dependent and facilitate cytomegalovirus persistence via coexpression of arginase-1. eLife 12 , e79165. 10.7554/eLife.79165 |
Ciacchi, Lisa, van de Garde, Martijn D.B., Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Farenc, Carine, Poelen, Martien C.M., Miners, Kelly L., Llerena, Carmen, Reid, Hugh H., Petersen, Jan, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Rossjohn, Jamie ORCID: https://orcid.org/0000-0002-2020-7522 and van Els, Cécile A.C.M. 2023. CD4+ T cell-mediated recognition of a conserved cholesterol-dependent cytolysin epitope generates broad antibacterial immunity. Immunity 56 (5) , pp. 1082-1097. 10.1016/j.immuni.2023.03.020 |
Man, Stephen ORCID: https://orcid.org/0000-0001-9103-1686, Redman, James E. ORCID: https://orcid.org/0000-0001-5492-2869, Cross, Deborah L., Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Can, Ilona, Davies, Bethan, Hashimdeen, Shaikh Shimaz, Reid, Reiss, Llewellyn-Lacey, Sian, Miners, Kelly L., Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Lissina, Anya, Brown, Paul E., Wooldridge, Linda, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737 and Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369 2021. Synthetic peptides with inadvertent chemical modifications can activate potentially autoreactive T cells. The Journal of Immunology 207 (4) , pp. 1009-1017. 10.4049/jimmunol.2000756 |
Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Knezevic, Lea, Dockree, Tamsin, McLaren, James E. ORCID: https://orcid.org/0000-0002-7021-5934, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Miners, Kelly L., Llewellyn-Lacey, Sian, Rubina, Anzelika, Francis, Ore, Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135, Bridgeman, John S., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, van den Berg, Hugo A. and Wooldridge, Linda 2021. CD8 coreceptor-mediated focusing can reorder the agonist hierarchy of peptide ligands recognized via the T cell receptor. Proceedings of the National Academy of Sciences 118 (29) , e2019639118. 10.1073/pnas.2019639118 |
Vlachava, Virginia-Maria ORCID: https://orcid.org/0000-0003-4233-7739, Murrell, Isa, Zhuang, Lihui, Aicheler, Rebecca J., Lim, Eleanor, Miners, Kelly L., Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Suárez, Nicolás M., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Davison, Andrew J., Wilkinson, Gavin W.G., Wills, Mark R., Weekes, Michael P., Wang, Eddie C.Y. ORCID: https://orcid.org/0000-0002-2243-4964 and Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182 2021. Monoclonal antibodies targeting nonstructural viral antigens can activate ADCC against human cytomegalovirus. Journal of Clinical Investigation 131 (4) , e139296. 10.1172/JCI139296 |
Kasatskaya, Sofya A., Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Egorov, Evgeniy S., Miners, Kelly L., Davydov, Alexey N., Metsger, Maria, Staroverov, Dmitry B., Matveyshina, Elena K., Shagina, Irina A., Mamedov, Ilgar Z., Izraelson, Mark, Shelyakin, Pavel V., Britanova, Olga V., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737 and Chudakov, Dmitriy M. 2020. Functionally specialized human CD4+ T-cell subsets express physicochemically distinct TCRs. eLife 9 , e57063. 10.7554/eLife.57063 |
Ahmed, Raya, Miners, Kelly L., Lahoz-Beneytez, Julio, Jones, Rhiannon E., Roger, Laureline, Baboonian, Christina, Zhang, Yan, Wang, Eddie C. Y. ORCID: https://orcid.org/0000-0002-2243-4964, Hellerstein, Marc K., McCune, Joseph M., Baird, Duncan M. ORCID: https://orcid.org/0000-0001-8408-5467, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Macallan, Derek C., Asquith, Becca and Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938 2020. CD57+ Memory T Cells Proliferate In Vivo. Cell Reports 33 (11) , 108501. 10.1016/j.celrep.2020.108501 |
Pearson, Frances E., Tullett, Kirsteen M., Leal-Rojas, Ingrid M., Haigh, Oscar L., Masterman, Kelly-Anne, Walpole, Carina, Bridgeman, John S., McLaren, James E. ORCID: https://orcid.org/0000-0002-7021-5934, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Miners, Kelly, Llewellyn-Lacey, Sian, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Tunger, Antje, Schmitz, Marc, Miles, John J, Lahoud, Mireille H and Radford, Kristen J 2020. Human CLEC9A antibodies deliver Wilms' tumor 1 (WT1) antigen to CD141+ dendritic cells to activate naïve and memory WT1‐specific CD8+ T cells. Clinical and Translational Immunology 9 10.1002/cti2.1141 |
Appanna, Gautham D, Pembroke, Thomas P I ORCID: https://orcid.org/0000-0002-2600-2034, Miners, Kelly L, Price, David A ORCID: https://orcid.org/0000-0001-9416-2737, Gallimore, Awen M ORCID: https://orcid.org/0000-0001-6675-7004, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938 and Godkin, Andrew J ORCID: https://orcid.org/0000-0002-1910-7567 2019. Rituximab depletion of intrahepatic B cells to control refractory hepatic autoimmune overlap syndrome. QJM: An International Journal of Medicine 112 (10) , pp. 793-795. 10.1093/qjmed/hcz161 |
Wong, Emily B., Gold, Marielle C., Meermeier, Erin W., Xulu, Bongiwe Z., Khuzwayo, Sharon, Sullivan, Zuri A., Mahyari, Eisa, Rogers, Zoe, Kløverpris, Hénrik, Sharma, Prabhat K., Worley, Aneta H., Lalloo, Umesh, Baijnath, Prinita, Ambaram, Anish, Naidoo, Leon, Suleman, Moosa, Madansein, Rajhmun, McLaren, James E. ORCID: https://orcid.org/0000-0002-7021-5934, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Miners, Kelly L., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Behar, Samuel M., Nielsen, Morten, Kasprowicz, Victoria O., Leslie, Alasdair, Bishai, William R., Ndung'u, Thumbi and Lewinsohn, David M. 2019. TRAV1-2+ CD8+ T-cells including oligoconal expansions of MAIT cells are enriched in the airways in human tuberculosis. Communications Biology 2 (1) , -. 10.1038/s42003-019-0442-2 |
Mohammed, Rebar N., Wehenkel, Sophie C., Galkina, Elena V., Yates, Emma-Kate, Preece, Graham, Newman, Andrew, Watson, H. Angharad, Ohme, Julia, Bridgeman, John S., Durairaj, Ruban R. P., Moon, Owen R., Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Miners, Kelly L., Dolton, Garry, Troeberg, Linda, Kashiwagi, Masahide, Murphy, Gillian, Nagase, Hideaki, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Matthews, R. James, Knauper, Vera ORCID: https://orcid.org/0000-0002-3965-9924 and Ager, Ann ORCID: https://orcid.org/0000-0002-5763-8908 2019. ADAM17-dependent proteolysis of L-selectin promotes early clonal expansion of cytotoxic T cells. Scientific Reports 9 , 5487. 10.1038/s41598-019-41811-z |
McLaren, James ORCID: https://orcid.org/0000-0002-7021-5934, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Marsden, Morgan, Miners, Kelly L., Llewellyn-Lacey, Sian, Grant, Emma J., Rubina, Anzelika, Gimeno Brias, Silvia, Gostick, Emma, Stacey, Maria A., Orr, Selinda J., Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737 and Humphreys, Ian R. ORCID: https://orcid.org/0000-0002-9512-5337 2019. IL-33 augments virus-specific memory T Cell inflation and potentiates the efficacy of an attenuated cytomegalovirus-based vaccinea. Journal of Immunology 202 (3) , pp. 943-955. 10.4049/jimmunol.1701757 |
Boelen, Lies, Debebe, Bisrat, Silveira, Marcos, Salam, Arafa, Makinde, Julia, Roberts, Chrissy h., Wang, Eddie C. Y. ORCID: https://orcid.org/0000-0002-2243-4964, Frater, John, Gilmour, Jill, Twigger, Katie, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Miners, Kelly L., Jayaraman, Jyothi, Traherne, James A., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Qi, Ying, Martin, Maureen P., Macallan, Derek C., Thio, Chloe L., Astemborski, Jacquie, Kirk, Gregory, Donfield, Sharyne M., Buchbinder, Susan, Khakoo, Salim I., Goedert, James J., Trowsdale, John, Carrington, Mary, Kollnberger, Simon and Asquith, Becca 2018. Inhibitory killer cell immunoglobulin-like receptors strengthen CD8+ T cell-mediated control of HIV-1, HCV, and HTLV-1. Science Immunology 3 (29) , eaao2892. 10.1126/sciimmunol.aao2892 |
Costa del Amo, Pedro, Beneytez, Julio Lahoz, Boelen, Lies, Ahmed, Raya, Miners, Kelly L., Zhang, Yan, Roger, Laureline, Jones, Rhiannon E., Marraco, Silvia A. Fuertes, Speiser, Daniel E., Baird, Duncan M. ORCID: https://orcid.org/0000-0001-8408-5467, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Macallan, Derek and Asquith, Becca 2018. Human TSCM cell dynamics in vivo are compatible with long-lived immunological memory and stemness. PLoS Biology 16 (6) , e2005523. 10.1371/journal.pbio.2005523 |
Wun, Kwok S., Reijneveld, Josephine F., Cheng, Tan-Yun, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Uldrich, Adam P., Le Nours, Jérôme, Miners, Kelly L., McLaren, James E. ORCID: https://orcid.org/0000-0002-7021-5934, Grant, Emma J., Haigh, Oscar L., Watkins, Thomas S., Suliman, Sara, Iwany, Sarah, Jimenez, Judith, Calderon, Roger, Tamara, Kattya L., Leon, Segundo R., Murray, Megan B., Mayfield, Jacob A., Altman, John D., Purcell, Anthony W., Miles, John J., Godfrey, Dale I., Gras, Stephanie, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Van Rhijn, Ildiko, Moody, D. Branch and Rossjohn, Jamie ORCID: https://orcid.org/0000-0002-2020-7522 2018. T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids. Nature Immunology 19 , pp. 397-406. 10.1038/s41590-018-0065-7 |
McCully, Michelle L., Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Andrews, Robert, Jones, Rhiannon E., Miners, Kelly L., Roger, Laureline, Baird, Duncan M. ORCID: https://orcid.org/0000-0001-8408-5467, Cameron, Mark J., Jessop, Zita M., Whitaker, Iain S., Davies, Eleri L., Price, David A. and Moser, Bernhard ORCID: https://orcid.org/0000-0002-4354-4572 2018. CCR8 expression defines tissue-resident memory T cells in human skin. Journal of Immunology 200 (5) , pp. 1639-1650. 10.4049/jimmunol.1701377 |
Lissina, Anna, McLaren, James E. ORCID: https://orcid.org/0000-0002-7021-5934, Ilander, Mette, Andersson, Emma I., Lewis, Catherine S., Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Herman, Andrew, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Llewellyn-Lacey, Sian, Miners, Kelly L., Gostick, Emma, Melenhorst, J. Joseph, Barrett, A. John, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Mustjoki, Satu and Wooldridge, Linda 2018. Divergent roles for antigenic drive in the aetiology of primary versus dasatinib-associated CD8+ TCR-Vβ+ expansions. Scientific Reports 8 (1) , 2534. 10.1038/s41598-017-18062-x |
Van Braeckel-Budimir, Natalija, Gras, Stephanie, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Josephs, Tracy M., Pewe, Lecia, Urban, Stina L., Miners, Kelly L., Farenc, Carine, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Rossjohn, Jamie ORCID: https://orcid.org/0000-0002-2020-7522 and Harty, John T. 2017. A T cell receptor locus harbors a malaria-specific immune response gene. Immunity 47 (5) , 835-847.e4. 10.1016/j.immuni.2017.10.013 |
Murrell, Isa, Bedford, Carmen, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Miners, Kelly L., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Tomasec, Peter, Wilkinson, Gavin W. G. ORCID: https://orcid.org/0000-0002-5623-0126 and Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182 2017. The pentameric complex drives immunologically covert cell -cell transmission of wild-type human cytomegalovirus. Proceedings of the National Academy of Sciences 114 (23) , pp. 6104-6109. 10.1073/pnas.1704809114 |
Ahmed, Raya, Roger, Laureline, Costa del Amo, Pedro, Miners, Kelly L., Jones, Rhiannon E., Boelen, Lies, Fali, Tinhinane, Elemans, Marjet, Zhang, Yan, Appay, Victor, Baird, Duncan M. ORCID: https://orcid.org/0000-0001-8408-5467, Asquith, Becca, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Macallan, Derek C. and Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938 2016. Human stem cell-like memory T cells are maintained in a state of dynamic flux. Cell Reports 17 (11) , pp. 2811-2818. 10.1016/j.celrep.2016.11.037 |
Watson, H. Angharad, Dolton, Garry Michael, Ohme, Julia, Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Vigar, Miriam, Wehenkel, Sophie, Hindley, James, Mohammed, Rebar, Miners, Kelly, Luckwell, Rhys A, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Matthews, R James and Ager, Ann ORCID: https://orcid.org/0000-0002-5763-8908 2016. Purity of transferred CD8+ T cells is crucial for safety and efficacy of combinatorial tumor immunotherapy in the absence of SHP-1. Immunology and Cell Biology 94 (8) 10.1038/icb.2016.45 |
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