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Number of items: 30.

Riseley, Ross, Carneiro, Aitor, Mu, Zhilin, Alkahtani, Rawiyah, Kariuki, Benson ORCID: https://orcid.org/0000-0002-8658-3897, Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064 and Jones, D. Heulyn 2025. Unusual reactivity of 2-amino-1H-indole-3-carboxylate esters. ARKIVOC 2025 (5) , 202512417. 10.24820/ark.5550190.p012.417
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Reeks, Judith, Mahajan, Pravin, Clark, Mellissa, Cowan, Suzanna R., Di Daniel, Elena, Earl, Christopher P., Fisher, Samantha, Holvey, Rhian S., Jackson, Scott M., Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611, Morgillo, Carmine M., Mortenson, Paul N., O'Reilly, Marc, Richardson, Caroline J., Schöpf, Patrick, Tams, Daniel M., Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064, Ward, Simon E. ORCID: https://orcid.org/0000-0002-8745-8377, Whibley, Stuart, Williams, Pamela A. and Johnson, Christopher N. 2025. High throughput cryo-EM provides structural understanding for modulators of the lysosomal ion channel TRPML1. Structure 33 (8) , pp. 1374-1385. 10.1016/j.str.2025.05.014
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Best, Hannah L., Cook, Sophie R., Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064 and Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611 2025. Niemann-Pick C-like endo-lysosomal dysfunction in DHDDS patient cells, a congenital disorder of glycosylation, can be treated with miglustat. International Journal of Molecular Sciences 26 (4) , 1471. 10.3390/ijms26041471
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Cubitt, Jonathan, Davies, Mari, Riseley, Ross, Evans, Gabrielle, Gardiner, Sian E., Kariuki, Benson M. ORCID: https://orcid.org/0000-0002-8658-3897, Ward, Simon E. ORCID: https://orcid.org/0000-0002-8745-8377, Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611, Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064 and Jones, D. Heulyn 2024. Beware of N-Benzoyloxybenzamides. Molecules 29 (21) , 5143. 10.3390/molecules29215143
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Best, Hannah L., Williamson, Lainey J., Heath, Emily A., Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064, Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611 and Berry, Colin ORCID: https://orcid.org/0000-0002-9943-548X 2023. The role of glycoconjugates as receptors for insecticidal proteins. FEMS Microbiology Reviews 47 (4) 10.1093/femsre/fuad026
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Somogyi, Aleksandra, Kirkham, Emily D., Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611, Winston, Jincy, Allen, Nicholas D. ORCID: https://orcid.org/0000-0003-4009-186X, Mackrill, John J., Anderson, Karen E., Hawkins, Phillip T., Gardiner, Sian E., Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064, Sims, Rebecca ORCID: https://orcid.org/0000-0002-3885-1199, Boland, Barry and O'Neill, Cora 2023. The synthetic TRPML1 agonist ML-SA1 rescues Alzheimer-related alterations of the endosomal-autophagic-lysosomal system. Journal of Cell Science 136 (6) , jcs259875. 10.1242/jcs.259875
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Fenn, Gareth D., Alenazy, Deemah M., Pope, Simon ORCID: https://orcid.org/0000-0001-9110-9711, Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611 and Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064 2023. Development of a novel anthraquinone-derived fluorescent lysosomal probe. Molecular Genetics and Metabolism 138 (2) , 107097. 10.1016/j.ymgme.2022.107097
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Honeybun, Llinos, Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064 and Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611 2023. Unbiased phenotypic drug screen for CLN3 disease. Presented at: 19th Annual WORLDSymposium™ 2023, Orlando, Florida, 21-26 February 2023. Molecular Genetics and Metabolism. , vol.138 (2) Elsevier, p. 167. 10.1016/j.ymgme.2022.107150

Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064, Zhu, Jingwen, Honeybun, Llinos, Gardiner, Sian, Hanley, Marcus, Best, Hannah and Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611 2023. Measuring ion flux via lysosomal channels: Primary and secondary assays for drug discovery across the lysosomal disorders. Presented at: 19th Annual WORLDSymposium™ 2023, Orlando, Florida, 21-26 February 2023. Molecular Genetics and Metabolism. , vol.138 (2) Elsevier, pp. 133-134. 10.1016/j.ymgme.2022.107353

Fenn, Gareth D., Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611 and Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064 2023. Investigation of cannabidiol as a potential therapeutic in Niemann-Pick disease. Presented at: 19th Annual WORLDSymposium™ 2023, Orlando, Florida, 21-26 February 2023. Molecular Genetics and Metabolism. , vol.138 (2) Elsevier, p. 42. 10.1016/j.ymgme.2022.107098

Cook, Sophie R., Kirkham, Emily D., Best, Hannah, Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064, Serpi, Michaela ORCID: https://orcid.org/0000-0002-6162-7910, Pertusati, Fabrizio ORCID: https://orcid.org/0000-0003-4532-9101 and Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611 2023. Investigating lysosomal and cellular phenotypes of the lysosomal disorder cystinosis. Presented at: 19th Annual WORLDSymposium™ 2023, Orlando, Florida, 21-26 February 2023. Molecular Genetics and Metabolism. , vol.138 (2) Elsevier, p. 28. 10.1016/j.ymgme.2022.107061

Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611, Best, Hannah L., Alshehri, Abdullah S., Honeybun, Llinos and Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064 2023. Glycosphingolipid reduction with miglustat as a therapeutic strategy for CLN3 and other neuronal ceroid lipofuscinoses. Presented at: 19th Annual WORLDSymposium™ 2023, Orlando, Florida, 21-26 February 2023. Molecular Genetics and Metabolism. , vol.138 (2) Elsevier, p. 84. 10.1016/j.ymgme.2022.107212

Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064, Francis, Laura, Fenn, Gareth, Best, Hannah and Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611 2023. Filipin composition and imaging modality dramatically affect cellular cholesterol visualisation with implications for assessing cholesterol levels and localisation across the lysosomal disorders. Presented at: 19th Annual WORLDSymposium™ 2023, Orlando, Florida, 21-26 February 2023. Molecular Genetics and Metabolism. , vol.138 (2) Elsevier, p. 133. 10.1016/j.ymgme.2022.107352

Best, Hannah L., Badell-Grau, Rafael A., Shipley, Katie, Alshehri, Abdullah S., Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064 and Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611 2023. Disease phenotypes present in CLN7 patient fibroblasts are improved following treatment to reduce glycosphingolipid synthesis. Presented at: 19th Annual WORLDSymposium™ 2023, Orlando, Florida, 21-26 February 2023. Molecular Genetics and Metabolism. , vol.138 (2) Elsevier, p. 17. 10.1016/j.ymgme.2022.107029

Best, Hannah, Honeybun, Llinos, Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064 and Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611 2023. The Batten disease associated protein CLN3 is required for the efflux of lysosomal K. Presented at: 19th Annual WORLDSymposium™ 2023, Orlando, Florida, 21-26 February 2023. Molecular Genetics and Metabolism. , vol.138 (2) Elsevier, p. 47. 10.1016/j.ymgme.2022.107030

Davies, Mari, Riseley, Ross, Jones, Dyfyr H. and Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064 2023. Acid ceramidase inhibition as a mechanism to treat lysosomal disorders. Molecular Genetics and Metabolism 138 (2) , 107069. 10.1016/j.ymgme.2022.107069

Best, Hannah L., Williamson, Lainey J., Lipka-Lloyd, Magdalena, Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064, Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369 and Berry, Colin ORCID: https://orcid.org/0000-0002-9943-548X 2022. The crystal structure of Bacillus thuringiensis Tpp80Aa1 and its interaction with galactose-containing glycolipids. Toxins 14 (12) , 863. 10.3390/toxins14120863
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Cook, Sophie R, Bladen, Cerys, Smith, Johanna, Maguire, Emily, Copner, Jordan, Fenn, Gareth D, Wager, Kim ORCID: https://orcid.org/0000-0001-8107-9600, Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064 and Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611 2020. Visualisation of cholesterol and ganglioside GM1 in zebrafish models of Niemann-Pick type C disease and Smith-Lemli-Opitz syndrome using light sheet microscopy. Histochemistry and Cell Biology 154 , pp. 565-578. 10.1007/s00418-020-01925-2
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Badell Grau, Rafael A., Cuff, Jordan Patrick, Kelly, Brendan P., Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064 and Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611 2020. Investigating the prevalence of reactive online searching in the COVID-19 pandemic. Journal of Medical Internet Research 22 (10) , e19791. 10.2196/19791
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Fenn, Gareth, Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064, Atack, John R. ORCID: https://orcid.org/0000-0002-3410-791X and Bax, Benjamin D. ORCID: https://orcid.org/0000-0003-1940-3785 2020. Crystallization and structure of ebselen bound to cysteine 141 of human inositol monophosphatase (IMPase). Acta Crystallographica Section F: Structural Biology Communications F76 (10) , pp. 469-476. 10.1107/S2053230X20011310
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Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611 and Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064 2020. Biosynthesis and signalling functions of central and peripheral nervous system neurosteroids in health and disease. Essays in Biochemistry 64 (3) , pp. 591-606. 10.1042/EBC20200043
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Cook, Sophie R., Badell-Grau, Rafael A., Kirkham, Emily D., Jones, Kimberley M., Kelly, Brendan M., Winston, Jincy, Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064, Allen, Nicholas D. ORCID: https://orcid.org/0000-0003-4009-186X and Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611 2020. Detrimental effect of zwitterionic buffers on lysosomal homeostasis in cell lines and iPSC-derived neurons. AMRC Open Research 2 , 21. 10.12688/amrcopenres.12903.1
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Morimoto, Marie, Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064, Ammous, Zineb, Song, Xiaofei, Strauss, Kevin A., Pehlivan, Davut, Gonzaga-Jauregui, Claudia, Puffenberger, Erik G., Holst, Charles R., Karaca, Ender, Brigatti, Karlla W., Maguire, Emily, Coban-Akdemir, Zeynep H., Amagata, Akiko, Lau, C. Christopher, Chepa-Lotrea, Xenia, Macnamara, Ellen, Tos, Tulay, Isikay, Sedat, Nehrebecky, Michele, Overton, John D., Klein, Matthew, Markello, Thomas C., Posey, Jennifer E., Adams, David R., Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611, Lupski, James R., Gahl, William A. and Malicdan, May Christine V. 2018. Bi-allelic CCDC47 variants cause a disorder characterized by woolly hair, liver dysfunction, dysmorphic features, and global developmental delay. American Journal of Human Genetics 103 (5) , pp. 794-807. 10.1016/j.ajhg.2018.09.014

Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064 and Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611 2015. Regulation of TRPML1 function. Biochemical Society Transactions 43 (3) , pp. 442-446. 10.1042/BST20140311

Kaisaki, Pamela J., Otto, Georg W., McGouran, Joanna F., Toubal, Amine, Argoud, Karène, Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064, Finlay, Clare, Caldérari, Sophie, Bihoreau, Marie-Thérèse, Kessler, Benedikt M., Gauguier, Dominique and Mott, Richard 2014. Genetic control of differential acetylation in diabetic rats. PLoS ONE 9 (4) , e94555. 10.1371/journal.pone.0094555
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Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064, Hue, Christophe, Fearnside, Jane, Rothwell, Alice R., Lockstone, Helen E., Caldérari, Sophie, Wilder, Steven P., Cazier, Jean-Baptiste, Scott, James and Gauguier, Dominique 2013. Nutrigenomics of high fat diet induced obesity in mice suggests relationships between susceptibility to fatty liver disease and the proteasome. PLoS ONE 8 (12) , e82825. 10.1371/journal.pone.0082825

Prömel, Simone, Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064, Dixon, John, Zahn, Dirk, Colledge, William H., Doran, Joanne, Carlton, Mark B.L., Grosse, Johannes, Schöneberg, Torsten, Russ, Andreas P. and Langenhan, Tobias 2012. Characterization and functional study of a cluster of four highly conserved orphan adhesion-GPCR in mouse. Developmental Dynamics 241 (10) , pp. 1591-1602. 10.1002/dvdy.23841

Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611, Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064, Peterneva, Ksenia and Platt, Frances M. 2010. Endolysosomal calcium regulation and disease. Biochemical Society Transactions 38 (6) , pp. 1458-1464. 10.1042/BST0381458

Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064, Prömel, Simone, Langenhan, Tobias, Dixon, John, Zahn, Dirk, Colledge, William H., Doran, Joanne, Carlton, Mark B. L., Davies, Ben, Aparicio, Samuel A. J. R., Grosse, Johannes and Russ, Andreas P. 2010. The orphan adhesion-GPCR GPR126 is required for embryonic development in the mouse. PLoS ONE 5 (11) , e14047. 10.1371/journal.pone.0014047
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Langenhan, Tobias, Prömel, Simone, Mestek, Lamia, Esmaeili, Behrooz, Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064, Hennig, Christian, Kohara, Yuji, Avery, Leon, Vakonakis, Ioannis, Schnabel, Ralf and Russ, Andreas P. 2009. Latrophilin signaling links anterior-posterior tissue polarity and oriented cell divisions in the C. elegans embryo. Developmental Cell 17 (4) , pp. 494-504. 10.1016/j.devcel.2009.08.008

This list was generated on Thu Oct 30 11:10:52 2025 GMT.


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