Bong Lee, Jong, Zang, Xiaowei, Zgair, Atheer, Qian Ooi, Ting, Foley, David W, Voronin, Gregory, Kagan, Leonid, Soukarieh, Fadi, Gao, Rui, Shao, Hao, Tying Soh, Wan, Hwan Kim, Tae, Gi Kim, Min, Yun, Hwi-yeol, Wilson, Anthony J., Fischer, Peter M. and Gershkovich, Pavel 2021. Postprandial administration but not controlled release in the colon increases oral bioavailability of DF030263, a promising drug candidate for chronic lymphocytic leukemia. European Journal of Pharmaceutics and Biopharmaceutics 165 , pp. 106-112. 10.1016/j.ejpb.2021.05.006 |
Shao, Hao, Foley, David, Huang, Shiliang, Abbas, Abdullahi, Lam, Frankie, Gershkovich, Pavel, Bradshaw, Tracey, Pepper, Chris, Fischer, Peter and Wang, Shudong 2021. Structure-based design of highly selective 2,4,5-trisubstituted pyrimidine CDK9 inhibitors as anti-cancer agents. European Journal of Medicinal Chemistry 214 , 113244. 10.1016/j.ejmech.2021.113244 |
Willetts, Steffan and Foley, David W. 2020. True or false? challenges and recent highlights in the development of aspirin prodrugs. European Journal of Medicinal Chemistry 192 , 112200. 10.1016/j.ejmech.2020.112200 |
Bell, Mark, Foley, David, Naylor, Claire, Wood, Gavin, Robinson, Colin, Riley, Jennifer, Epemolu, Ola, Ellis, Lucy, Scullion, Paul, Shishikura, Yoko, Osuna-Cabello, Maria, Ferguson, Liam, Pinto, Erika, Fletcher, Daniel, Katz, Elad, McLean, W. H. Irwin, Wyatt, Paul, Read, Kevin D and Woodland, Andrew 2019. Discovery of soft-drug topical tool modulators of Sphingosine-1-phosphate Receptor 1 (S1PR1). ACS Medicinal Chemistry Letters 10 (3) , pp. 341-347. 10.1021/acsmedchemlett.8b00616 |
Bell, Mark, Foley, David, Naylor, Claire, Robinson, Colin, Riley, Jennifer, Epemolu, Ola, Scullion, Paul, Shishikura, Yoko, Katz, Elad, McLean, W. H. Irwin, Wyatt, Paul, Read, Kevin D. and Woodland, Andrew 2018. Discovery of super soft-drug modulators of sphingosine-1-phosphate receptor 1. Bioorganic & Medicinal Chemistry Letters 28 (19) , pp. 3255-3259. 10.1016/j.bmcl.2018.07.044 |
Foley, David W., Pathak, Ravindra B., Phillips, Theresa R., Wilson, Gayle L., Bailey, Patrick D., Pieri, Myrtani, Senan, Anish and Meredith, David 2018. Thiodipeptides targeting the intestinal oligopeptide transporter as a general approach to improving oral drug delivery. European Journal of Medicinal Chemistry 156 , pp. 180-189. 10.1016/j.ejmech.2018.06.064 |
Pearson, Lesley-Anne and Foley, David William 2017. Communicating our science to our customers: drug discovery in five simple experiments. ACS Medicinal Chemistry Letters 8 (2) , pp. 143-144. 10.1021/acsmedchemlett.7b00015 |
Foley, David W., Bermudez, Isabel, Bailey, Patrick D. and Meredith, David 2016. A cyclosporine derivative is a substrate of the oligopeptide transporter PepT1. MedChemComm 7 (5) , pp. 999-1002. 10.1039/C5MD00575B |
Assefnia, Shahin, Dakshanamurthy, Sivanesan, Auvil, Jaime M. Guidry, Hampel, Constanze, Anastasiadis, Panos Z., Kallakury, Bhaskar, Uren, Aykut, Foley, David W., Brown, Milton L., Shapiro, Lawrence, Brenner, Michael, Haigh, David and Byers, Stephen W. 2015. Cadherin-11 in poor prognosis malignancies and rheumatoid arthritis: common target, common therapies. Oncotarget 5 (6) , pp. 1458-1474. 10.18632/oncotarget.1538 |
Shao, Hao, Shi, Shenhua, Foley, David W., Lam, Frankie, Abbas, Abdullah Y., Liu, Xiangrui, Huang, Shiliang, Jiang, Xiangrui, Baharin, Nadiah, Fischer, Peter M. and Wang, Shudong 2013. Synthesis, structure-activity relationship and biological evaluation of 2,4,5-trisubstituted pyrimidine CDK inhibitors as potential anti-tumour agents. European Journal of Medicinal Chemistry 70 , pp. 447-455. 10.1016/j.ejmech.2013.08.052 |
Shao, H., Shi, S., Huang, S, Hole, A., Abbas, A., Baumli, S., Liu, X., Lam, F., Foley, David, Fischer, P., Noble, M., Endicott, J., Pepper, Christopher John and Wang, S. 2013. Substituted 4-(Thiazol-5-yl)-2-(phenylamino)pyrimidines are highly active CDK9 inhibitors: synthesis, X-ray crystal structures, structure activity relationship, and anticancer activities. Journal of Medicinal Chemistry 56 (3) , pp. 640-659. 10.1021/jm301475f |
Foley, David, Rajamanickam, Jeyaganesh, Bailey, Patrick and Meredith, David 2010. Bioavailability through PepT1: the role of computer modelling in intelligent drug design. Current Computer Aided-Drug Design 6 (1) , pp. 68-78. 10.2174/157340910790980133 |
Foley, David, Pieri, Myrtani, Pettecrew, Rachel, Price, Richard, Miles, Stephen, Lam, Ho Kam, Bailey, Patrick and Meredith, David 2009. The in vitro transport of model thiodipeptide prodrugs designed to target the intestinal oligopeptide transporter, PepT1. Organic & Biomolecular Chemistry 7 (18) , pp. 3652-3656. 10.1039/b909221h |
Foley, David, Bailey, Patrick, Pieri, Myrtani and Meredith, David 2009. Targeting ketone drugs towards transport by the intestinal peptide transporter, PepT1. Organic & Biomolecular Chemistry 7 (6) , pp. 1064-1067. 10.1039/b818606e |
Mace, Oliver J., Lister, Norma, Morgan, Emma, Shepherd, Emma, Affleck, Julie, Helliwell, Philip, Bronk, John R., Kellett, George L., Meredith, David, Boyd, Richard, Pieri, Myrtani, Bailey, Pat D., Pettcrew, Rachel and Foley, David 2009. An energy supply network of nutrient absorption coordinated by calcium and T1R taste receptors in rat small intestine. The Journal of Physiology 587 (1) , pp. 195-210. 10.1113/jphysiol.2008.159616 |