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Number of items: 65.

Ursino, Moreno, Villacampa, Guillermo, Rekowski, Jan, Dimairo, Munyaradzi, Solovyeva, Olga, Ashby, Deborah, Berlin, Jordan, Boix, Oliver, Calvert, Melanie, Chan, An-Wen, Coschi, Courtney H., Evans, Thomas R Jeffry, Garrett-Mayer, Elizabeth, Golub, Robert M., Guo, Christina, Hayward, Kathryn S., Hopewell, Sally, Isaacs, John D., Ivy, S. Percy, Jaki, Thomas, Kholmanskikh, Olga, Kightley, Andrew, Lee, Shing, Liu, Rong, Mander, Adrian ORCID: https://orcid.org/0000-0002-0742-9040, Marshall, Lynley V., Matcham, James, Patel, Dhrusti, Peck, Richard, Rantell, Khadija Rerhou, Richards, Dawn P., Rouhifard, Mahtab, Seymour, Lesley, Tanaka, Yoshiya, Weir, Christopher J., de Bono, Johann and Yap, Christina 2025. SPIRIT-DEFINE explanation and elaboration: recommendations for enhancing quality and impact of early phase dose-finding clinical trials protocols. EClinicalMedicine 79 , 102988. 10.1016/j.eclinm.2024.102988
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Rekowski, Jan, Guo, Christina, Solovyeva, Olga, Dimairo, Munyaradzi, Rouhifard, Mahtab, Patel, Dhrusti, Alger, Emily, Ashby, Deborah, Berlin, Jordan, Boix, Oliver, Calvert, Melanie, Chan, An-Wen, Coschi, Courtney H., de Bono, Johann, Evans, Thomas R. Jeffry, Garrett-Mayer, Elizabeth, Golub, Robert M., Hayward, Kathryn S., Hopewell, Sally, Isaacs, John D., Ivy, S. Percy, Jaki, Thomas, Kholmanskikh, Olga, Kightley, Andrew, Lee, Shing, Liu, Rong, Maia, Israel, Mander, Adrian ORCID: https://orcid.org/0000-0002-0742-9040, Marshall, Lynley V., Matcham, James, Peck, Richard, Rantell, Khadija Rerhou, Richards, Dawn P., Seymour, Lesley, Tanaka, Yoshiya, Ursino, Moreno, Weir, Christopher J. and Yap, Christina 2025. CONSORT-DEFINE explanation and elaboration: recommendations for enhancing reporting quality and impact of early phase dose-finding clinical trials. EClinicalMedicine 79 , 102987. 10.1016/j.eclinm.2024.102987
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Wych, Julie, Brunner, Martina, Stenson, Rachel, Chumura, Piotr Jaroslaw, Danne, Thomas, Mander, Adrian Paul ORCID: https://orcid.org/0000-0002-0742-9040, Mathieu, Chantal, Dayan, Colin ORCID: https://orcid.org/0000-0002-6557-3462 and Pieber, Thomas R. 2024. Investigating the effect of verapamil on preservation of beta-cell function in adults with newly diagnosed type 1 diabetes mellitus (Ver-A-T1D): protocol for a randomised, double-blind, placebo-controlled, parallel-group, multicentre trial. BMJ Open 14 (11) , e091597. 10.1136/bmjopen-2024-091597
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Walburn, Jessica, Norton, Sam, Sarkany, Robert, Canfield, Martha, Sainsbury, Kirby, McCrone, Paul, Araújo-Soares, Vera, Morgan, Myfanwy, Boadu, Janette, Foster, Lesley, Heydenreich, Jakob, Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040, Sniehotta, Falko F., Wulf, Hans Christian and Weinman, John 2024. A personalised and systematically designed adherence intervention improves photoprotection in adults with Xeroderma Pigmentosum (XP): Results of the XPAND randomised controlled trial. British Journal of Dermatology , ljae393. 10.1093/bjd/ljae393
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Goncalves, Maria B., Wu, Yue, Clarke, Earl, Grist, John, Moehlin, Julien, Mendoza-Parra, Marco Antonio, Hobbs, Carl, Kalindjian, Barret, Fok, Henry, Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040, Hassanin, Hana, Bendel, Daryl, Täubel, Jörg, Mant, Tim, Carlstedt, Thomas, Jack, Julian and Corcoran, Jonathan P. T. 2024. C286, an orally available retinoic acid receptor β agonist drug, regulates multiple pathways to achieve spinal cord injury repair. Frontiers in Molecular Neuroscience 17 , 1411384. 10.3389/fnmol.2024.1411384
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Yin, Zhulin, Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040, de Bono, Johann S., Zheng, Haiyan and Yap, Christina 2024. Handling incomplete or late-onset toxicities in early-phase dose-finding clinical trials: current practice and future prospects. JCO Precision Oncology 8 10.1200/PO.23.00441
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Goncalves, Maria B., Mant, Tim, Täubel, Jörg, Clarke, Earl, Hassanin, Hana, Bendel, Daryl, Fok, Henry, Posner, John, Holmes, Jane, Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040 and Corcoran, Jonathan P. T. 2023. Phase 1 safety, tolerability, pharmacokinetics and pharmacodynamic results of KCL‐286, a novel retinoic acid receptor‐β agonist for treatment of spinal cord injury, in male healthy participants. British Journal of Clinical Pharmacology 89 (12) , pp. 3573-3583. 10.1111/bcp.15854
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Yap, Christina, Solovyeva, Olga, de Bono, Johann, Rekowski, Jan, Patel, Dhrusti, Jaki, Thomas, Mander, Adrian ORCID: https://orcid.org/0000-0002-0742-9040, Evans, Thomas R Jeffry, Peck, Richard, Hayward, Kathryn S, Hopewell, Sally, Ursino, Moreno, Rantell, Khadija Rerhou, Calvert, Melanie, Lee, Shing, Kightley, Andrew, Ashby, Deborah, Chan, An-Wen, Garrett-Mayer, Elizabeth, Isaacs, John D, Golub, Robert, Kholmanskikh, Olga, Richards, Dawn, Boix, Oliver, Matcham, James, Seymour, Lesley, Ivy, S Percy, Marshall, Lynley V, Hommais, Antoine, Liu, Rong, Tanaka, Yoshiya, Berlin, Jordan, Espinasse, Aude, Dimairo, Munyaradzi and Weir, Christopher J 2023. Enhancing reporting quality and impact of early phase dose-finding clinical trials: CONSORT Dose-finding Extension (CONSORT-DEFINE) guidance. BMJ 383 , e076387. 10.1136/bmj-2023-076387
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Yap, Christina, Rekowski, Jan, Ursino, Moreno, Solovyeva, Olga, Patel, Dhrusti, Dimairo, Munyaradzi, Weir, Christopher J, Chan, An-Wen, Jaki, Thomas, Mander, Adrian ORCID: https://orcid.org/0000-0002-0742-9040, Evans, Thomas R Jeffry, Peck, Richard, Hayward, Kathryn S, Calvert, Melanie, Rantell, Khadija Rerhou, Lee, Shing, Kightley, Andrew, Hopewell, Sally, Ashby, Deborah, Garrett-Mayer, Elizabeth, Isaacs, John, Golub, Robert, Kholmanskikh, Olga, Richards, Dawn P, Boix, Oliver, Matcham, James, Seymour, Lesley, Ivy, S Percy, Marshall, Lynley V, Hommais, Antoine, Liu, Rong, Tanaka, Yoshiya, Berlin, Jordan, Espinasse, Aude and de Bono, Johann 2023. Enhancing quality and impact of early phase dose-finding clinical trial protocols: SPIRIT Dose-finding Extension (SPIRIT-DEFINE) guidance. BMJ 383 , e076386. 10.1136/bmj-2023-076386
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Espinasse, Aude, Solovyeva, Olga, Dimairo, Munyaradzi, Weir, Christopher, Jaki, Thomas, Mander, Adrian ORCID: https://orcid.org/0000-0002-0742-9040, Kightley, Andrew, Evans, Jeffry, Lee, Shing, Bedding, Alun, Hopewell, Sally, Rantell, Khadija, Liu, Rong, Chan, An-Wen, De Bono, Johann and Yap, Christina 2023. SPIRIT and CONSORT extensions for early phase dose-finding clinical trials: the DEFINE (DosE-FIndiNg Extensions) study protocol. BMJ Open 13 (3) , e068173. 10.1136/bmjopen-2022-068173
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Williamson, S. Faye, Grayling, Michael J., Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040, Noor, Nurulamin M., Savage, Joshua S., Yap, Christina and Wason, James M.S. 2022. Subgroup analyses in randomised controlled trials frequently categorised continuous subgroup information. Journal of Clinical Epidemiology 150 , pp. 72-79. 10.1016/j.jclinepi.2022.06.017
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Dunger, David B., Bruggraber, Sylvaine F. A., Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040, Marcovecchio, M. Loredana, Tree, Timothy, Chmura, Piotr Jaroslaw, Knip, Mikael, Schulte, Anke M., Mathieu, Chantal, Mathieu, C., Gillard, P., Casteels, K., Overbergh, L., Dunger, D., Wallace, C., Evans, M., Thankamony, A., Hendriks, E., Bruggraber, S., Peakman, M., Tree, T., Morgan, N., Richardson, S., Todd, J., Wicker, L., Mander, A. ORCID: https://orcid.org/0000-0002-0742-9040, Dayan, C., Alhadj Ali, M., Pieber, T., Eizirik, D., Cnop, M., Brunak, S., Pociot, F., Johannesen, J., Rossing, P., Legido Quigley, C., Mallone, R., Scharfmann, R., Boitard, C., Knip, M., Otonkoski, T., Veijola, R., Lahesmaa, R., Oresic, M., Toppari, J., Danne, T., Ziegler, A. G., Achenbach, P., Rodriguez-Calvo, T., Solimena, M., Bonifacio, E., Speier, S., Holl, R., Dotta, F., Chiarelli, F., Marchetti, P., Bosi, E., Cianfarani, S., Ciampalini, P., de Beaufort, C., Dahl-Jørgensen, K., Skrivarhaug, T., Joner, G., Krogvold, L., Jarosz-Chobot, P., Battelino, T., Thorens, B., Gotthardt, M., Roep, B., Nikolic, T., Zaldumbide, A., Lernmark, A., Lundgren, M., Costecalde, G., Strube, T., Schulte, A., Nitsche, A., von Herrath, M., Wesley, J., Napolitano-Rosen, A., Thomas, M., Schloot, N., Goldfine, A., Waldron-Lynch, F., Kompa, J., Vedala, A., Hartmann, N., Nicolas, G., van Rampelbergh, J., Bovy, N., Dutta, S., Soderberg, J., Ahmed, S., Martin, F., Agiostratidou, G., Koralova, A., Willemsen, R., Smith, A., Anand, B., Puthi, V., Zac-Varghese, S., Datta, V., Dias, R., Sundaram, P., Vaidya, B., Patterson, C., Owen, K., Piel, B., Heller, S., Randell, T., Gazis, T., Bismuth Reismen, E., Carel, J-C, Riveline, J-P, Gautier, J-F, Andreelli, F., Travert, F., Cosson, E., Penfornis, A., Petit, C., Feve, B., Lucidarme, N., Cosson, E., Beressi, J-P, Ajzenman, C., Radu, A., Greteau-Hamoumou, S., Bibal, C., Meissner, T., Heidtmann, B., Toni, S., Rami-Merhar, B., Eeckhout, B., Peene, B., Vantongerloo, N., Maes, T., Gommers, L., Marcovecchio, M.L., Vela, J. and Latres, E. 2022. INNODIA Master Protocol for the evaluation of investigational medicinal products in children, adolescents and adults with newly diagnosed type 1 diabetes. Trials 23 (1) , 414. 10.1186/s13063-022-06259-z
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Grayling, Michael J. and Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040 2022. Optimised point estimators for multi-stage single-arm phase II oncology trials. Journal of Biopharmaceutical Statistics 32 (6) , pp. 817-831. 10.1080/10543406.2022.2041656
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Grayling, Michael J. and Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040 2021. Two-stage single-arm trials are rarely analyzed effectively or reported adequately. JCO Precision Oncology 5 , pp. 1813-1820. 10.1200/PO.21.00276

Wilhelm-Benartzi, Charlotte S. ORCID: https://orcid.org/0000-0003-4927-6158, Miller, Sarah E., Bruggraber, Sylvaine, Picton, Diane, Wilson, Mark, Gatley, Katrina, Chhabra, Anita, Marcovecchio, M. Loredana, Hendriks, A. Emile J., Morobé, Hilde, Chmura, Piotr Jaroslaw, Bond, Simon, Aschemeier-Fuchs, Bärbel, Knip, Mikael, Tree, Timothy, Overbergh, Lut, Pall, Jaivier, Arnaud, Olivier, Haller, Michael J., Nitsche, Almut, Schulte, Anke M., Mathieu, Chantal, Mander, Adrian ORCID: https://orcid.org/0000-0002-0742-9040 and Dunger, David 2021. Study protocol: Minimum effective low dose: anti-human thymocyte globulin (MELD-ATG): phase II, dose ranging, efficacy study of antithymocyte globulin (ATG) within 6 weeks of diagnosis of type 1 diabetes. BMJ Open 11 (12) , e053669. 10.1136/bmjopen-2021-053669
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Grayling, Michael J. and Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040 2021. Accounting for variation in the required sample size in the design of group-sequential trials. Contemporary Clinical Trials 107 , 106459. 10.1016/j.cct.2021.106459
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Bennett, Maxine, White, Simon, Best, Nicky and Mander, Adrian ORCID: https://orcid.org/0000-0002-0742-9040 2021. A novel equivalence probability weighted power prior for using historical control data in an adaptive clinical trial design: a comparison to standard methods. Pharmaceutical Statistics 20 (3) , pp. 462-484. 10.1002/pst.2088
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Law, Martin, Grayling, Michael J. and Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040 2021. A stochastically curtailed two‐arm randomised phase II trial design for binary outcomes. Pharmaceutical Statistics 20 (2) , pp. 212-228. 10.1002/pst.2067
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Dimairo, Munyaradzi, Pallmann, Philip ORCID: https://orcid.org/0000-0001-8274-9696, Wason, James, Todd, Susan, Jaki, Thomas, Julious, Steven A., Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040, Weir, Christopher J., Koenig, Franz, Walton, Marc K., Nicholl, Jon P., Coates, Elizabeth, Biggs, Katie, Hamasaki, Toshimitsu, Proschan, Michael A., Scott, John A., Ando, Yuki, Hind, Daniel and Altman, Douglas G. 2020. The Adaptive designs CONSORT Extension (ACE) statement: a checklist with explanation and elaboration guideline for reporting randomised trials that use an adaptive design. Trials 21 , 528. 10.1186/s13063-020-04334-x
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Dimairo, Munyaradzi, Pallmann, Philip ORCID: https://orcid.org/0000-0001-8274-9696, Wason, James, Todd, Susan, Jaki, Thomas, Julious, Steven A, Mander, Adrian P ORCID: https://orcid.org/0000-0002-0742-9040, Weir, Christopher J, Koenig, Franz, Walton, Marc K, Nicholl, Jon P, Coates, Elizabeth, Biggs, Katie, Hamasaki, Toshimitsu, Proschan, Michael A, Scott, John A, Ando, Yuki, Hind, Daniel and Altman, Douglas G 2020. The Adaptive designs CONSORT Extension (ACE) Statement: a checklist with explanation and elaboration guideline for reporting randomised trials that use an adaptive design. BMJ 369 , m115. 10.1136/bmj.m115
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Pallmann, Philip ORCID: https://orcid.org/0000-0001-8274-9696, Wan, Fang, Mander, Adrian P ORCID: https://orcid.org/0000-0002-0742-9040, Wheeler, Graham M, Yap, Christina, Clive, Sally, Hampson, Lisa V and Jaki, Thomas 2020. Designing and evaluating dose-escalation studies made easy: the MoDEsT web app. Clinical Trials 17 (2) , pp. 147-156. 10.1177/1740774519890146
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Bennett, Maxine and Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040 2020. Designs for adding a treatment arm to an ongoing clinical trial. Trials 21 (1) , 251. 10.1186/s13063-020-4073-1
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Grayling, Michael J, Dimairo, Munyaradzi, Mander, Adrian P ORCID: https://orcid.org/0000-0002-0742-9040 and Jaki, Thomas F 2019. A review of perspectives on the use of randomization in phase II oncology trials. JNCI: Journal of the National Cancer Institute 111 (12) , pp. 1255-1262. 10.1093/jnci/djz126
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Wych, Julie, Grayling, Michael J. and Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040 2019. Sample size re-estimation in crossover trials: application to the AIM HY-INFORM study. Trials 20 (1) , 665. 10.1186/s13063-019-3724-6
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Dimairo, Munya, Pallmann, Philip ORCID: https://orcid.org/0000-0001-8274-9696, Wason, James, Todd, Sue, Jaki, Thomas, Julious, Steven A., Mander, Adrian ORCID: https://orcid.org/0000-0002-0742-9040, Weir, Christopher J., Koenig, Franz, Walton, Marc K., Nicholl, Jon P., Coates, Elizabeth, Biggs, Katie, Hamasaki, Toshimitsu, Proschan, Michael A., Scott, John A., Ando, Yuki, Hind, Daniel and Altman, Douglas G. 2019. Introducing the Adaptive designs CONSORT Extension (ACE) Statement to improve reporting of randomised trials that use an adaptive design (P-7). Presented at: 5th International Clinical Trials Methodology Conference (ICTMC 2019), Brighton, UK, 6-9 October 2019. Trials. BioMed Central, -. 10.1186/s13063-019-3688-6
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Grayling, Michael J., Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040 and Wason, James M. S. 2019. Two-stage adaptive designs for three-treatment bioequivalence studies. Statistics in Biopharmaceutical Research 11 (4) , pp. 360-374. 10.1080/19466315.2019.1654911

Grayling, Michael J., Wason, James M. S. and Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040 2019. Exact group sequential designs for two-arm experiments with Poisson distributed outcome variables. Communications in Statistics - Theory and Methods 50 (1) , pp. 18-34. 10.1080/03610926.2019.1628273
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Grayling, Michael J., Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040 and Wason, James M. S. 2019. Admissible multiarm stepped-wedge cluster randomized trial designs. Statistics in Medicine 38 (7) , pp. 1103-1119. 10.1002/sim.8022
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Wheeler, Graham M., Sweeting, Michael J. and Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040 2019. A Bayesian model‐free approach to combination therapy phase I trials using censored time‐to‐toxicity data. Journal of the Royal Statistical Society: Series C 68 (2) , pp. 309-329. 10.1111/rssc.12323
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Wheeler, Graham M., Sweeting, Michael J. and Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040 2017. Toxicity-dependent feasibility bounds for the escalation with overdose control approach in phase I cancer trials. Statistics in Medicine 36 (16) , pp. 2499-2513. 10.1002/sim.7280
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Wheeler, Graham M., Sweeting, Michael J., Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040, Lee, Shing M. and Cheung, Ying Kuen K. 2017. Modelling semi-attributable toxicity in dual-agent phase I trials with non-concurrent drug administration. Statistics in Medicine 36 (2) , pp. 225-241. 10.1002/sim.6912
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Spencer, Amy V., Harbron, Chris, Mander, Adrian ORCID: https://orcid.org/0000-0002-0742-9040, Wason, James and Peers, Ian 2016. An adaptive design for updating the threshold value of a continuous biomarker. Statistics in Medicine 35 (27) , p. 4909. 10.1002/sim.7042
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Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040 and Sweeting, Michael J. 2015. A product of independent beta probabilities dose escalation design for dual-agent phase I trials. Statistics in Medicine 34 (8) , 1261--1276. 10.1002/sim.6434
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Walker, Celia G, Holzapfel, Christina, Loos, Ruth J F, Mander, Adrian P ORCID: https://orcid.org/0000-0002-0742-9040, Klopp, Norman, Illig, Thomas, Caterson, Ian D, Hauner, Hans and Jebb, Susan A 2013. Genetic predisposition to an adverse lipid profile limits the improvement in total cholesterol in response to weight loss. Obesity 21 (12) , pp. 2589-95. 10.1002/oby.20328

Sweeting, Michael, Mander, Adrian ORCID: https://orcid.org/0000-0002-0742-9040 and Sabin, Tony 2013. bcrm: Bayesian Continual Reassessment Method designs for Phase I dose-finding trials. Journal of Statistical Software 54 (13) 10.18637/jss.v054.i13
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Harrington, Jennifer A., Wheeler, Graham M., Sweeting, Michael J., Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040 and Jodrell, Duncan I. 2013. Adaptive designs for dual-agent phase I dose-escalation studies. Nature Reviews Clinical Oncology 10 (5) , pp. 277-288. 10.1038/nrclinonc.2013.35

Browning, Lucy M., Walker, Celia G., Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040, West, Annette L., Madden, Jackie, Gambell, Joanna M., Young, Stephen, Wang, Laura, Jebb, Susan A. and Calder, Philip C. 2012. Incorporation of eicosapentaenoic and docosahexaenoic acids into lipid pools when given as supplements providing doses equivalent to typical intakes of oily fish. American Journal of Clinical Nutrition 96 (4) , pp. 748-758. 10.3945/ajcn.112.041343

Wason, James M. S. and Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040 2012. Minimizing the Maximum Expected Sample Size in Two-Stage Phase II Clinical Trials with Continuous Outcomes. Journal of Biopharmaceutical Statistics 22 (4) , pp. 836-852. 10.1080/10543406.2010.528104

Sweeting, Michael J. and Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040 2012. Escalation strategies for combination therapy Phase I trials. Pharmaceutical Statistics 11 (3) , pp. 258-266. 10.1002/pst.1497

Walker, Celia G., Loos, Ruth J. F., Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040, Jebb, Susan A., Frost, Gary S., Griffin, Bruce A., Lovegrove, Julie A., Sanders, Thomas A. B. and Bluck, Les J. 2012. Genetic predisposition to type 2 diabetes is associated with impaired insulin secretion but does not modify insulin resistance or secretion in response to an intervention to lower dietary saturated fat. Genes and Nutrition 7 (4) , pp. 529-536. 10.1007/s12263-012-0284-8
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Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040, Wason, James M. S., Sweeting, Michael J. and Thompson, Simon G. 2012. Admissible two-stage designs for phase II cancer clinical trials that incorporate the expected sample size under the alternative hypothesis. Pharmaceutical Statistics 11 (2) , pp. 91-96. 10.1002/pst.501

Mander, A. P. ORCID: https://orcid.org/0000-0002-0742-9040, Ahern, A. L., Caterson, I. D., Hauner, H. and Jebb, S. A. 2012. Weight loss in a commercial setting: Authors' reply. Lancet 379 (9820) , p. 1003. 10.1016/S0140-6736(12)60425-5

Wason, James M. S., Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040 and Thompson, Simon G. 2012. Optimal multistage designs for randomised clinical trials with continuous outcomes. Statistics in Medicine 31 (4) , pp. 301-312. 10.1002/sim.4421

Jebb, Susan A., Ahern, Amy L., Olson, Ashley D., Aston, Louise M., Holzapfel, Christina, Stoll, Julia, Amann-Gassner, Ulrike, Simpson, Annie E., Fuller, Nicholas R., Pearson, Suzanne, Lau, Namson S., Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040, Hauner, Hans and Caterson, Ian D. 2011. Primary care referral to a commercial provider for weight loss treatment versus standard care: a randomised controlled trial. Lancet 378 (9801) , pp. 1485-1492. 10.1016/S0140-6736(11)61344-5

Thompson, Simon, Ekelund, Ulf, Jebb, Susan, Lindroos, Anna Karin, Mander, Adrian ORCID: https://orcid.org/0000-0002-0742-9040, Sharp, Stephen, Turner, Rebecca and Wilks, Desiree 2011. A proposed method of bias adjustment for meta-analyses of published observational studies. International Journal of Epidemiology 40 (3) , pp. 765-777. 10.1093/ije/dyq248
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Wason, James M. S., Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040 and Eisen, Tim G. 2011. Reducing sample sizes in two stage phase II cancer trials by using continuous tumour shrinkage end-points. European Journal of Cancer 47 (7) , pp. 983-989. 10.1016/j.ejca.2010.12.007

Wilks, Desiree C., Sharp, Stephen J., Ekelund, Ulf, Thompson, Simon G., Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040, Turner, Rebecca M., Jebb, Susan A. and Lindroos, Anna Karin 2011. Objectively measured physical activity and fat mass in children: A bias-adjusted meta-analysis of prospective studies. PLoS ONE 6 (2) , e17205.. 10.1371/journal.pone.0017205
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Wilks, Desiree C., Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040, Jebb, Susan A., Thompson, Simon G., Sharp, Stephen J., Turner, Rebecca M. and Lindroos, Anna Karin 2011. Dietary energy density and adiposity: Employing bias adjustments in a meta-analysis of prospective studies. BMC Public Health 11 , -. 10.1186/1471-2458-11-48

da Costa, Teresa H. M., Haisma, Hinke, Wells, Jonathan C. K., Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040, Whitehead, Roger G. and Bluck, Leslie J. C. 2010. How much human milk do infants consume? Data from 12 countries using a standardized stable isotope methodology. Journal of Nutrition 140 (12) , pp. 2227-2232. 10.3945/jn.110.123489

Bluck, Leslie J. C., Jackson, Sarah J., Vlasakakis, Georgios and Mander, Adrian ORCID: https://orcid.org/0000-0002-0742-9040 2010. Bayesian hierarchical methods to interpret the C-13-octanoic acid breath test for gastric emptying. Digestion 83 (1-2) , pp. 96-107. 10.1159/000316823

Mander, A. P. ORCID: https://orcid.org/0000-0002-0742-9040 and Thompson, S. G. 2010. Two-stage designs optimal under the alternative hypothesis for phase II cancer clinical trials. Contemporary Clinical Trials 31 (6) , pp. 572-578. 10.1016/j.cct.2010.07.008
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Cook, Natalie, Basu, Bristi, Biswas, Swethajit, Kareclas, Paula, Mann, Colette, Palmer, Cheryl, Thomas, Anne, Nicholson, Steve, Morgan, Bruno, Lomas, David, Sirohi, Bhawna, Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040, Middleton, Mark and Corrie, Pippa G. 2010. A phase 2 study of vatalanib in metastatic melanoma patients. European Journal of Cancer 46 (15) , pp. 2671-2673. 10.1016/j.ejca.2010.07.014

Aston, Louise M., Laccetti, Roberta, Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040, Hall, Rosemary, Moore, Carmel S. and Jebb, Susan A. 2010. No difference in the 24-hour interstitial fluid glucose profile with modulations to the glycemic index of the diet. Nutrition 26 (3) , pp. 290-295. 10.1016/j.nut.2009.05.010

Aston, L. M., Laccetti, R., Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040, Hall, R., Moore, C.S. and Jebb, S.A. 2010. No difference in the 24-hour interstitial fluid glucose profile with modulations to the glycemic index of the diet. Nutrition 26 (3) , pp. 290-295. 10.1016/j.nut.2009.05.010

Siervo, M., Corander, M., Mander, A. P. ORCID: https://orcid.org/0000-0002-0742-9040, Browning, L. M. and Jebb, S. A. 2010. Acute effects of hyperglycaemia on asymmetric dimethylarginine (ADMA), adiponectin and inflammatory markers (IL-6, hs-CRP) in overweight and obese women with metabolic syndrome. British Journal of Biomedical Science 67 (4) , pp. 216-218. 10.1080/09674845.2010.11730322

Sripanyakorn, Supannee, Jughaohsingh, Ravin, Mander, Adrian ORCID: https://orcid.org/0000-0002-0742-9040, Davidson, Sarah L., Thompson, Richard P. H. and Powell, Jonathan J. 2009. Moderate ingestion of alcohol is associated with acute ethanol-induced suppression of circulating CTX in a PTH-independent fashion. Journal of Bone and Mineral Research 24 (8) , pp. 1380-1388. 10.1359/JBMR.090222

Wilks, D. C., Mander, Adrian P. ORCID: https://orcid.org/0000-0002-0742-9040, Jebb, S. A., Thompson, S.G., Sharp, S., Turner, R. M. and Lindroos, A.K. 2009. Dietary energy density and weight gain: A bias-adjusted meta-analysis of prospective studies [Poster Abstract]. Obesity 17 (S2) , S314. 10.1038/oby.2009.286

Prynne, C. J., Mander, A. ORCID: https://orcid.org/0000-0002-0742-9040, Wadsworth, M. E. J. and Stephern, A. M. 2009. Diet and glycosylated haemoglobin in the 1946 British birth cohort. European Journal of Clinical Nutrition 63 (9) , pp. 1084-1090. 10.1038/ejcn.2009.43

Chatfield, Mark and Mander, Adrian ORCID: https://orcid.org/0000-0002-0742-9040 2009. The Skillings-Mack test (Friedman test when there are missing data). Stata Journal 9 (2) , pp. 299-305. 10.1177/1536867X0900900208

Cunnington, Marianne, Webb, David, Qizilbash, Nawab, Blum, David, Mander, Adrian ORCID: https://orcid.org/0000-0002-0742-9040, Jonsson Funk, Michele and Weil, John 2008. Risk of ischaemic cardiovascular events from selective cyclooxygenase-2 inhibitors in osteoarthritis. Pharmacoepidemiology and Drug Safety 17 (6) , pp. 601-608. 10.1002/pds.1590

Johnson, L., Mander, A. P. ORCID: https://orcid.org/0000-0002-0742-9040, Jones, L. R., Emmett, P. M. and Jebb, S. A. 2008. A prospective analysis of dietary energy density at age 5 and 7 years and fatness at 9 years among UK children. International Journal of Obesity 32 (4) , pp. 586-593. 10.1038/sj.ijo.0803746

Johnson, Laura, Mander, Adrian ORCID: https://orcid.org/0000-0002-0742-9040, Jones, Louise R., Emmett, Pauline M. and Jebb, Susan A. 2008. Energy-dense, low-fiber, high-fat dietary pattern is associated with increased fatness in childhood. American Journal of Clinical Nutrition 87 (4) , pp. 846-854. 10.1093/ajcn/87.4.846

Mander, A. P. ORCID: https://orcid.org/0000-0002-0742-9040 and Bansal, A. 2006. Stepwise haplotype analysis: are LD patterns repeatable? Human Genomics 2 (6) , 376. 10.1186/1479-7364-2-6-376

Henseik, A. E., Sawcer, S. J., Feakes, R., Deans, J., Mander, A. ORCID: https://orcid.org/0000-0002-0742-9040, Akesson, E., Roxburgh, R., Coraddu, F., Smith, S. and Compston, D. A. S. 2002. HLA-DR 15 is associated with female sex and younger age at diagnosis in multiple sclerosis. Journal of Neurology, Neurosurgery and Psychiatry 72 (2) , pp. 184-187. 10.1136/jnnp.72.2.184

Meyers, A, Marshall, H, Nowotny, P, Smemo, S, Mander, A ORCID: https://orcid.org/0000-0002-0742-9040, Holmans, P., Ertekin-Taner, N., Ronald, J., Younkin, S., Tucker, H. M., Estus, S., Crook, R., Hardy, J., Dunstan, M., Hamshere, M., O'Donovan, M., Jones, L., Williams, J. and Owen, M. J. 2002. INFORMATION REQUESTED Follow-up of replicated linkage results on chromosome 10: Putative role of the urokinase plasminogen activator gene in risk for late-onset Alzheimer's disease. Neurobiology of Aging 23 (1) , S310.

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