Pritchard, Manon F. ORCID: https://orcid.org/0000-0002-5135-4744, Powell, Lydia C. ORCID: https://orcid.org/0000-0002-8641-0160, Adams, Jennifer Y.M., Menzies, Georgina ORCID: https://orcid.org/0000-0002-6600-6507, Khan, Saira, Tondervik, Anne, Sletta, Havard, Olav, Aarstad, Skjåk-Bræk, Gudmund, McKenna, Stephen, Buurma, Niklaas J. ORCID: https://orcid.org/0000-0003-0260-5057, Farnell, Damian J.J. ORCID: https://orcid.org/0000-0003-0662-1927, Rye, Philip D., Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117 and Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 2023. Structure–activity relationships of low molecular weight alginate oligosaccharide therapy against Pseudomonas aeruginosa. Biomolecules 13 (9) , 1366. 10.3390/biom13091366 |
Xue, Wenya, Pritchard, Manon F. ORCID: https://orcid.org/0000-0002-5135-4744, Khan, Saira, Powell, Lydia C., Stokniene, Joana, Wu, Jingxiang, Claydon, Nicholas ORCID: https://orcid.org/0000-0002-4151-1515, Reddell, Paul, Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 and Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117 2023. Defining in vitro topical antimicrobial and antibiofilm activity of epoxy-tigliane structures against oral pathogens. Journal of Oral Microbiology 15 (1) , 2241326. 10.1080/20002297.2023.2241326 |
Powell, Lydia C. ORCID: https://orcid.org/0000-0002-8641-0160, Adams, Jennifer Y.M., Quoraishi, Sadik, Py, Charlene, Oger, Anais, Gazze, Salvatore A., Francis, Lewis W., von Ruhland, Christopher, Owens, David, Rye, Philip D., Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117, Pritchard, Manon F. ORCID: https://orcid.org/0000-0002-5135-4744 and Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 2023. Alginate oligosaccharides enhance the antifungal activity of nystatin against candidal biofilms. Frontiers in Cellular and Infection Microbiology 13 , 1122340. 10.3389/fcimb.2023.1122340 |
Yang, Qiu E., MacLean, Craig, Papkou, Andrei, Pritchard, Manon ORCID: https://orcid.org/0000-0002-5135-4744, Powell, Lydia ORCID: https://orcid.org/0000-0002-8641-0160, Thomas, David ORCID: https://orcid.org/0000-0001-7319-5820, Andrey, Diego O., Li, Mei, Spiller, Brad ORCID: https://orcid.org/0000-0002-9117-6911, Yang, Wang and Walsh, Timothy R. ORCID: https://orcid.org/0000-0003-4315-4096 2020. Compensatory mutations modulate the competitiveness and dynamics of plasmid-mediated colistin resistance in Escherichia coli clones. ISME Journal 14 , pp. 861-865. 10.1038/s41396-019-0578-6 |
Pritchard, Manon F. ORCID: https://orcid.org/0000-0002-5135-4744, Oakley, Juliette L., Brilliant, Charles D., Rye, Philip D., Forton, Julian ORCID: https://orcid.org/0000-0002-0580-0432, Doull, Iolo J. M., Ketchell, Ian, Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117, Thomas, David W. and Lewis, Paul D. 2019. Mucin structural interactions with an alginate oligomer mucolytic in cystic fibrosis sputum. Vibrational Spectroscopy 103 , 102932. 10.1016/j.vibspec.2019.102932 |
Powell, Lydia C. ORCID: https://orcid.org/0000-0002-8641-0160, Pritchard, Manon F. ORCID: https://orcid.org/0000-0002-5135-4744, Ferguson, Elaine L. ORCID: https://orcid.org/0000-0002-0125-0234, Powell, Kate A. ORCID: https://orcid.org/0000-0002-8641-0160, Patel, Shree U., Rye, Phil D., Sakellakou, Stavroula-Melina, Buurma, Niklaas J. ORCID: https://orcid.org/0000-0003-0260-5057, Brilliant, Charles D., Copping, Jack M., Menzies, Georgina E. ORCID: https://orcid.org/0000-0002-6600-6507, Lewis, Paul D., Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117 and Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 2018. Targeted disruption of the extracellular polymeric network of pseudomonas aeruginosa biofilms by alginate oligosaccharides. npj Biofilms and Microbiomes 4 , 13. 10.1038/s41522-018-0056-3 |
Jack, Alison A., Khan, Saira, Powell, Lydia C. ORCID: https://orcid.org/0000-0002-8641-0160, Pritchard, Manon F. ORCID: https://orcid.org/0000-0002-5135-4744, Beck, Konrad ORCID: https://orcid.org/0000-0001-5098-9484, Sadh, Hina, Sutton, Lucy, Cavaliere, Alessandra, Florence, Hannah, Rye, Philip D., Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 and Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117 2018. Alginate Oligosaccharide-Induced Modification of the lasI-lasR and rhlI-rhlR Quorum Sensing Systems in Pseudomonas aeruginosa. Antimicrobial Agents and Chemotherapy 62 (5) , e02318-17. 10.1128/AAC.02318-17 |
Yang, Qiu, Li, Mei, Spiller, Owen B. ORCID: https://orcid.org/0000-0002-9117-6911, Andrey, Diego O., Hinchliffe, Philip, Li, Hui, MacLean, Craig, Niumsup, Pannika, Powell, Lydia ORCID: https://orcid.org/0000-0002-8641-0160, Pritchard, Manon ORCID: https://orcid.org/0000-0002-5135-4744, Papkou, Andrei, Shen, Yingbo, Portal, Edward, Sands, Kirsty, Spencer, James, Tansawai, Uttapoln, Thomas, David ORCID: https://orcid.org/0000-0001-7319-5820, Wang, Shaolin, Wang, Yang, Shen, Jianzhong and Walsh, Timothy 2017. Balancing mcr-1 expression and bacterial survival is a delicate equilibrium between essential cellular defence mechanisms. Nature Communications 8 , 2054. 10.1038/s41467-017-02149-0 |
Pritchard, Manon ORCID: https://orcid.org/0000-0002-5135-4744, Jack, Alison, Powell, Lydia ORCID: https://orcid.org/0000-0002-8641-0160, Sadh, Hina, Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117, Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 and Rye, Philip D 2017. Alginate Oligosaccharides modify hyphal infiltration of Candida albicans in an in vitro model of invasive Human Candidosis. Journal of Applied Microbiology 123 (3) , pp. 625-636. 10.1111/jam.13516 |
Pritchard, Manon F. ORCID: https://orcid.org/0000-0002-5135-4744, Powell, Lydia C. ORCID: https://orcid.org/0000-0002-8641-0160, Jack, Alison A., Powell, Kate ORCID: https://orcid.org/0000-0002-8641-0160, Beck, Konrad ORCID: https://orcid.org/0000-0001-5098-9484, Florance, Hannah, Forton, Julian, Rye, Philip D., Dessen, Arne, Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117 and Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 2017. A low-molecular-weight alginate oligosaccharide disrupts pseudomonal microcolony formation and enhances antibiotic effectiveness. Antimicrobial Agents and Chemotherapy 61 (9) , e00762-17. 10.1128/AAC.00762-17 |
Pritchard, Manon F. ORCID: https://orcid.org/0000-0002-5135-4744, Powell, Lydia C. ORCID: https://orcid.org/0000-0002-8641-0160, Khan, Saira, Griffiths, Peter C., Mansour, Omar T., Schweins, Ralf, Beck, Konrad ORCID: https://orcid.org/0000-0001-5098-9484, Buurma, Niklaas J. ORCID: https://orcid.org/0000-0003-0260-5057, Dempsey, Christopher E., Wright, Chris J., Rye, Philip D., Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117, Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 and Ferguson, Elaine L. ORCID: https://orcid.org/0000-0002-0125-0234 2017. The antimicrobial effects of the alginate oligomer OligoG CF-5/20 are independent of direct bacterial cell membrane disruption. Scientific Reports 7 , 44731. 10.1038/srep44731 |
Pritchard, Manon F. ORCID: https://orcid.org/0000-0002-5135-4744, Powell, Lydia C. ORCID: https://orcid.org/0000-0002-8641-0160, Menzies, Georgina E. ORCID: https://orcid.org/0000-0002-6600-6507, Lewis, Paul D., Hawkins, Karl, Wright, Chris, Doull, Iolo, Walsh, Timothy R., Onsoyen, Edvar, Dessen, Arne, Myrvold, Rolf, Rye, Philip D., Myrset, Astrid H., Stevens, Howard N. E., Hodges, Lee A., MacGregor, Gordon, Neilly, James B., Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117 and Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 2016. A new class of safe oligosaccharide polymer therapy to modify the mucus barrier of chronic respiratory disease. Molecular Pharmaceutics 13 (3) , pp. 863-872. 10.1021/acs.molpharmaceut.5b00794 |
Tondervik, Anne, Sletta, Havard, Klinkenberg, Geir, Emanuel, Charlotte, Powell, Lydia C. ORCID: https://orcid.org/0000-0002-8641-0160, Pritchard, Manon F. ORCID: https://orcid.org/0000-0002-5135-4744, Khan, Saira, Craine, Keiron M., Onsoyen, Edvar, Rye, Phil D., Wright, Chris, Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 and Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117 2014. Alginate oligosaccharides inhibit fungal cell growth and potentiate the activity of anti-fungals against Candida and Aspergillus spp. PLoS ONE , e112518. 10.1371/journal.pone.0112518 |
Pritchard, Manon ORCID: https://orcid.org/0000-0002-5135-4744
2014.
OligoG alginate nanomedicine mediated disruption of mucin barriers and microbial biofilms.
PhD Thesis,
Cardiff University.
Item availability restricted. |
Powell, Lydia C. ORCID: https://orcid.org/0000-0002-8641-0160, Pritchard, Manon F. ORCID: https://orcid.org/0000-0002-5135-4744, Emanuel, Charlotte, Onsøyen, Edvar, Rye, Philip D., Wright, Chris J., Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117 and Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 2014. A nanoscale characterization of the interaction of a novel alginate oligomer with the cell surface and motility of pseudomonas aeruginosa. American Journal of Respiratory Cell and Molecular Biology 50 (3) , pp. 483-492. 10.1165/rcmb.2013-0287OC |
Roberts, Jessica Louise, Khan, Saira, Emanuel, Charlotte, Powell, Lydia C. ORCID: https://orcid.org/0000-0002-8641-0160, Pritchard, Manon ORCID: https://orcid.org/0000-0002-5135-4744, Onsøyen, E., Myrvold, R., Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 and Hill, Katja E. ORCID: https://orcid.org/0000-0002-8590-0117 2013. An in vitro study of alginate oligomer therapies on oral biofilms. Journal of Dentistry 41 (10) , pp. 892-899. 10.1016/j.jdent.2013.07.011 |
Kelly, Grace, Pritchard, Manon ORCID: https://orcid.org/0000-0002-5135-4744 and Thompson, Shelagh 2012. The use of orofacial regulation therapy, including Palatal Plate Therapy, in the management of orofacial dysfunction in patients with Down syndrome. Journal of Disability and Oral Health 14 (1) , pp. 15-24. 10.4483/JDOH_015Kelly10 |
Pritchard, Manon ORCID: https://orcid.org/0000-0002-5135-4744, Kelly, Grace and Thompson, Shelagh 2012. A critical appraisal of the literature on Palatal Plate Therapy for orofacial dysfunction in patients with Down syndrome. Journal of Disability and Oral Health 13 , pp. 5-14. |