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Number of items: 52.

Smith, Paul J., McKeown, Stephanie R. and Patterson, Laurence H. 2023. Targeting DNA topoisomerase IIα (TOP2A) in the hypoxic tumour microenvironment using unidirectional hypoxia-activated prodrugs (uHAPs). IUBMB Life 75 (1) , pp. 40-54. 10.1002/iub.2619
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Smith, Paul J., Darzynkiewicz, Zbigniew and Errington, Rachel J. ORCID: https://orcid.org/0000-0002-8016-4376 2018. Nuclear cytometry and chromatin organization. Cytometry Part A 93 (8) , pp. 771-784. 10.1002/cyto.a.23521
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Smith, Paul J. 2016. Cytometric routes to single cell transcriptomics. Cytometry Part A 89 (5) , pp. 424-426. 10.1002/cyto.a.22869
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Smith, Paul J. 2016. EdU and BrdU incorporation resolve their differences. Cell Cycle 15 (12) , pp. 1527-1528. 10.1080/15384101.2016.1171654
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Al-Saraireh, Y, Sutherland, M, Springett, B, Freiberger, F, Ribeiro Morais, G, Loadman, P, Errington, Rachel ORCID: https://orcid.org/0000-0002-8016-4376, Smith, Paul, Fukuda, M, Gerardy-Schahn, R, Patterson, L, Shnyder, S and Falconer, R 2013. Pharmacological inhibition of polysialyltransferase ST8SiaII modulates tumour cell migration. PLoS ONE 8 (8) , e73366. 10.1371/journal.pone.0073366
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Mart, Robert J. ORCID: https://orcid.org/0000-0003-2196-5840, Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376, Watkins, Catherine Louise, Chappell, Sally Claire, Wiltshire, Marie, Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905, Smith, Paul James and Allemann, Rudolf Konrad ORCID: https://orcid.org/0000-0002-1323-8830 2013. BH3 helix-derived biophotonic nanoswitches regulate cytochrome c release in permeabilised cells. Molecular BioSystems 9 (11) , pp. 2597-2603. 10.1039/c3mb70246d
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Smith, Paul, Falconer, R. and Errington, Rachel ORCID: https://orcid.org/0000-0002-8016-4376 2013. Micro-community cytometry: sensing changes in cell health and glycoconjugate expression by imaging and flow cytometry. Journal of Microscopy 251 (2) , pp. 113-122. 10.1111/jmi.12060

Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376, Chappell, Sally Claire, Khan, Imtiaz A., Marquez Almuina, Nuria, Wiltshire, Marie, Griesdoorn, Victoria D. and Smith, Paul James 2013. Time-lapse microscopy approaches to track cell cycle and lineage progression at the single-cell level. Current Protocols in Cytometry 64 (12.4) 10.1002/0471142956.cy1204s64

Becker, H., Akagi, J., Skommer, J., Matuszek, A., Takeda, K., Fujimura, Y., Khoshmanesh, K., Kalantar-Zadeh, K., Mitchell, A., Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376, Smith, Paul James, Darzynkiewicz, Z., Wlodkowic, D. and Gray, B. 2013. Multivariate analysis of apoptotic markers versus cell cycle phase in living human cancer cells by microfluidic cytometry. Proceedings of SPIE 8615 , 86150W. 10.1117/12.2001474

Smith, Paul James, Furon, Emeline, Wiltshire, Marie, Chappell, Sally Claire, Patterson, Laurence H., Shnyder, Steven D., Falconer, Robert A. and Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376 2013. NCAM polysialylation during adherence transitions: live cell monitoring using an antibody-mimetic EGFP-endosialidase and the viability dye DRAQ7. Cytometry Part A 83A (7) , pp. 659-671. 10.1002/cyto.a.22306

Akagi, Jin, Kordon, Magdalena, Zhao, Hong, Matuszek, Anna, Dobrucki, Jurek, Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376, Smith, Paul James, Takeda, Kazuo, Darzynkiewicz, Zbigniew and Wlodkowic, Donald 2013. Real-time cell viability assays using a new anthracycline derivative DRAQ7®. Cytometry Part A 83A (2) , pp. 227-234. 10.1002/cyto.a.22228

Smith, Paul James, Wiltshire, Marie, Chappell, Sally Claire, Cosentino, Laura, Burns, Philip A., Pors, Klaus and Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376 2013. Kinetic analysis of intracellular Hoechst 33342-DNA interactions by flow cytometry: misinterpretation of side population status? Cytometry Part A 83A (1) , pp. 161-169. 10.1002/cyto.a.22224

Atari, M. I., Chappell, M. J., Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376, Smith, Paul James and Evans, N. D. 2011. Kinetic modelling of the role of the aldehyde dehydrogenase enzyme and the breast cancer resistance protein in drug resistance and transport. Computer Methods and Programs in Biomedicine 104 (2) , pp. 93-103. 10.1016/j.cmpb.2010.06.008

Khan, Imtiaz Ali, Lupi, Monica, Campbell, Lee, Chappell, Sally Claire, Brown, Martyn Rowan, Wiltshire, Marie, Smith, Paul James, Ubezio, Paolo and Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376 2011. Interoperability of time series cytometric data: A cross platform approach for modeling tumor heterogeneity. Cytometry Part A 79A (3) , pp. 214-226. 10.1002/cyto.a.21023

Rees, Paul, Brown, M. Rowan, Summers, Huw D., Holton, Mark D., Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376, Chappell, Sally Claire and Smith, Paul James 2011. A transfer function approach to measuring cell inheritance. BMC Systems Biology 5 , 31. 10.1186/1752-0509-5-31
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Fricke, Thomas, Mart, Robert J. ORCID: https://orcid.org/0000-0003-2196-5840, Watkins, Catherine Louise, Wiltshire, Marie, Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376, Smith, Paul James, Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 and Allemann, Rudolf Konrad ORCID: https://orcid.org/0000-0002-1323-8830 2011. Chemical synthesis of cell-permeable apoptotic peptides from in vivo produced proteins. Bioconjugate Chemistry 22 (9) , pp. 1763-1767. 10.1021/bc200338u

Summers, Huw D., Rees, Paul, Holton, Mark D., Rowan Brown, M., Chappell, Sally Claire, Smith, Paul James and Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376 2011. Statistical analysis of nanoparticle dosing in a dynamic cellular system. Nature Nanotechnology 6 (3) , pp. 170-174. 10.1038/nnano.2010.277

Davies, Luke Cynlais, Rosas, Marcela ORCID: https://orcid.org/0000-0002-9442-9638, Smith, Paul James, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 and Taylor, Philip Russel ORCID: https://orcid.org/0000-0003-0163-1421 2011. A quantifiable proliferative burst of tissue macrophages restores homeostatic macrophage populations after acute inflammation. European Journal of Immunology 41 (8) , pp. 2155-2164. 10.1002/eji.201141817

Brown, Martyn Rowan, Summers, Huw D., Rees, Paul, Smith, Paul James, Chappell, Sally Claire and Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376 2010. Flow-based cytometric analysis of cell cycle via simulated cell populations. PLOS Computational Biology 6 (4) , e1000741. 10.1371/journal.pcbi.1000741
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Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376, Brown, Martyn Rowan, Silvestre, Oscar, Njoh, Kerenza L., Chappell, Sally Claire, Khan, Imtiaz Ali, Rees, Paul, Wilks, Steve P., Smith, Paul James and Summers, Huw D. 2010. Single cell nanoparticle tracking to model cell cycle dynamics and compartmental inheritance. Cell Cycle 9 (1) , pp. 121-130. 10.4161/cc.9.1.10246

Brown, Martyn Rowan, Summers, Huw D., Rees, Paul, Chappell, Sally Claire, Silvestre, Oscar Ricardo, Khan, Imtiaz A., Smith, Paul James and Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376 2010. Long-term time series analysis of quantum dot encoded cells by deconvolution of the autofluorescence signal. Cytometry Part A 77A (10) , pp. 925-932. 10.1002/cyto.a.20936

Smith, Paul James, Furon, Emeline, Wiltshire, Marie, Campbell, Lee, Feeney, Graham P., Snyder, R. D. and Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376 2009. ABCG2-Associated Resistance to Hoechst 33342 and Topotecan in a Murine Cell Model with Constitutive Expression of Side Population Characteristics. Cytometry Part A 75A (11) , pp. 924-933. 10.1002/cyto.a.20800

Smith, Paul James, Khan, Imtiaz Ali and Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376 2009. Cytomics and cellular informatics - coping with asymmetry and heterogeneity in biological systems. Drug Discovery Today 14 (5-6) , pp. 271-277. 10.1016/j.drudis.2008.11.012

Holton, Mark D., Silvestre, Oscar, Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376, Smith, Paul James, Matthews, Daniel R., Rees, Paul and Summers, Huw D. 2009. Stroboscopic fluorescence lifetime imaging. Optics Express 17 (7) , pp. 5205-5216. 10.1364/OE.17.005205
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Biostatus Limited 2009. Anthraquinone and its derivatives. 7605280. [Patent].

University College Cardiff Consultants Ltd 2009. Microtrench and tumour proliferation assay. WO/2009/095666. [Patent].

Silvestre, Oscar, Holton, M. D., Summers, H. D., Smith, Paul James and Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376 2009. Hollow fiber: a biophotonic implant for live cells. Presented at: Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues VII, San Jose, CA, USA, 26-28 January 2009. Published in: Farkas, D. L., Nicolau, D. V. and Leif, R. C. eds. Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues VII. Proceedings of the SPIE (7182) Bellingham, WA: SPIE, 10.1117/12.809391

Smith, Paul James, Wiltshire, Marie, Furon, Emeline, Beattie, J. H. and Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376 2008. Impact of overexpression of metallothionein-1 on cell cycle progression and zinc toxicity. American Journal of Physiology - Cell Physiology 295 (5) , C1399-C1408. 10.1152/ajpcell.00342.2008

Smith, Paul James and Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376 2008. Dissecting the Cell Cycle: Loss of Genomic Integrity and Escape from Senescence [Abstract]. Cytometry Part B Clinical Cytometry 74B (6) , p. 390. 10.1002/cyto.b.20462

Cheung, S. Y. A., Evans, N. D., Chappell, M. J., Godfrey, K. R., Smith, Paul James and Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376 2008. Exploration of the intercellular heterogeneity of topotecan uptake into human breast cancer cells through compartmental modelling. Mathematical Biosciences 213 (2) , pp. 119-134. 10.1016/j.mbs.2008.03.008

Chappell, Michael J., Evans, N. D., Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376, Khan, Imtiaz Ali, Campbell, Lee, Ali, R., Godfrey, K. R. and Smith, Paul James 2008. A coupled drug kinetics-cell cycle model to analyse the response of human cells to intervention by topotecan. Computer Methods and Programs in Biomedicine 89 (2) , pp. 169-178. 10.1016/j.cmpb.2007.11.002

Summers, H. D., Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376, Smith, Paul James, Matthews, D. R. and Leary, J. F. 2008. Cytometric biochips with optically active surfaces for spatial engineering of fluorescence excitation. Presented at: Microfluidics, BioMEMS, and Medical Microsystems VI, San Jose, CA, USA, 21-22 January 2008. Published in: Wang, W. and Vauchier, C. eds. Microfluidics, BioMEMS, and Medical Microsystems VI (Proceedings Volume). Proceedings of the SPIE (6886) Bellingham, WA: SPIE, 10.1117/12.763645

Cancer Research Technology LTD 2008. Detecting objects. WO/2008/090330. [Patent].

Biostatus Limited 2008. Gel formulations and uses thereof. 20080182287. [Patent].

Summers, Huw D., Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376, Smith, Paul James, Chappell, Sally Claire, Rees, Paul, Brown, Martyn R. and Leary, James F. 2008. Cell-population tracking using quantum dots in flow cytometry. Presented at: Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications V, San Jose, CA, USA, 21-23 February 2008. Published in: Cartwright, A. N. and Nicolau, D. V. eds. Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications V. Proceedings of the SPIE (6865) Bellingham, WA: SPIE, 68650L. 10.1117/12.763602

Smith, Paul James, Marquez, Nuria, Wiltshire, Marie, Chappell, Sally Claire, Njoh, Kerenza, Campbell, Lee, Khan, Imtiaz Ali, Silvestre, Oscar and Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376 2007. Mitotic bypass via an occult cell cycle phase following DNA topoisomerase II inhibition in p53 functional human tumor cells. Cell Cycle 6 (16) , pp. 2071-2081. 10.4161/cc.6.16.4585

Khan, Imtiaz Ali, Husemann, P., Campbell, L, White, N. S., White, R. J., Smith, Paul James and Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376 2007. ProgeniDB - A novel cell lineage database for generation associated phenotypic behavior in cell-based assays. Cell Cycle 6 (7) , pp. 868-874. 10.4161/cc.6.7.4045

Njoh, Kerenza, Smith, Paul James, Chappell, Sally Claire, Summers, Huw D., Matthews, Daniel R., Morris, David, Goater, Andrew, Burt, Julian, Pope, Iestyn ORCID: https://orcid.org/0000-0002-4104-0389, Vojnovic, Boris, Ameer-Beg, Simon and Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376 2007. Live cell tracking on an optical biochip platform. Presented at: Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues V, San Jose, CA, USA, 20 January 2007. Published in: Farkas, D. L., Leif, R. C. and Nicolau, D. V. eds. Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues V. Proceedings of SPIE (6441) Bellingham, WA: SPIE, 64410X. 10.1117/12.698935

Matthews, Daniel R., Summers, Huw D., Njoh, Kerenza, Chappell, Sally Claire, Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376, Smith, Paul James, Pope, Iestyn ORCID: https://orcid.org/0000-0002-4104-0389, Barber, Paul, Vojnovic, Boris and Ameer-Beg, Simon 2007. A fluorescence biochip with a plasmon active surface. Presented at: Plasmonics in Biology and Medicine IV, San Jose, CA, USA, 20 January 2007. Published in: Vo-Dinh, Tuan and Lakowicz, Joseph R. eds. Plasmonics in Biology and Medicine IV. Proceedings of SPIE (6450) Bellingham, WA: SPIE, p. 645006. 10.1117/12.698948

Morris, David, Goater, Andrew, Menachery, Anoop, Burt, Julian, Rizvi, Nadeem, Matthews, Daniel R., Summers, Huw D., Pope, Iestyn ORCID: https://orcid.org/0000-0002-4104-0389, Vojnovic, Boris, Njoh, Kerenza, Chappell, Sally Claire, Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376 and Smith, Paul James 2007. Development of an optical biochip for the analysis of cell environment sensitivity. Presented at: Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues V, San Jose, CA, USA, 20 January 2007. Published in: Farkas, D. L., Leif, R. C. and Nicolau, D. V. eds. Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues V. Proceedings of SPIE (6441) Bellingham, WA: SPIE, 64410V. 10.1117/12.700052

Chong, E. Z., Matthews, D. R., Summers, H. D., Njoh, Kerenza, Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376 and Smith, Paul James 2007. Development of FRET-Based assays in the Far-Red using CdTe quantum dots. Journal of Biomedicine and Biotechnology 2007 , 54169. 10.1155/2007/54169
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Njoh, Kerenza L., Patterson, Laurence H., Zloh, Mire, Wiltshire, Marie, Fisher, Janet, Chappell, Sally Claire, Ameer-Beg, Simon, Bai, Yanhong, Matthews, Daniel, Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376 and Smith, Paul James 2006. Spectral analysis of the DNA targeting bisalkylaminoanthraquinone DRAQ5 in intact living cells. Cytometry Part A 69A (8) , pp. 805-814. 10.1002/cyto.a.20308

Matthews, Daniel Richard, Summers, Huw David, Njoh, Kerenza Louise, Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376, Smith, Paul James, Barber, P, Ameer-Beg, S and Vojnovic, B. 2006. Technique for Measurement of Fluorescence Lifetime by use of Stroboscopic Excitation and Continuous-Wave Detection. Applied Optics 45 (9) , pp. 2115-2123. 10.1364/AO.45.002115

Pors, Klaus, Plumb, Jane A., Brown, Robert, Teesdale-Spittle, Paul, Searcey, Mark, Smith, Paul James and Patterson, Laurence H. 2005. Development of nonsymmetrical 1,4-disubstituted anthraquinones that are potently active against cisplatin-resistant ovarian cancer cells. Journal of Medicinal Chemistry 48 (21) , pp. 6690-6695. 10.1021/jm050438f

Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376, Ameer-Beg, S. M., Vojnovic, Boris, Patterson, L. H., Zloh, M. and Smith, Paul James 2005. Advanced microscopy solutions for monitoring the kinetics and dynamics of drug-DNA targeting in living cells. Advanced Drug Delivery Reviews 57 (10) , pp. 153-167. 10.1016/j.addr.2004.05.005

Marquez, Nuria, Chappell, Sally Claire, Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X, Teesdale-Spittle, Paul, Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376 and Smith, Paul James 2004. Microtubule stress modifies intra-nuclear location of Msh2 in mouse embryonic fibroblasts. Cell Cycle 3 , pp. 662-671.

Marquez, Nuria, Chappell, Sally Claire, Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X, Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376, Smith, Paul James and Court, Jonathan 2003. Single cell tracking reveals that Msh2 is a key component of an early-acting DNA damage-activated G2 checkpoint. Oncogene 22 (48) , pp. 7642-7648. 10.1038/sj.onc.1206876

Davis, Terence ORCID: https://orcid.org/0000-0003-2780-0262, Singhrao, Simarjit Kaur, Wyllie, Fiona Sandra, Haughton, Michele Fleur, Smith, Paul James, Wiltshire, Marie, Wynford-Thomas, David, Jones, Christopher John, Faragher, Richard G. A. and Kipling, David Glyn 2003. Telomere-based proliferative lifespan barriers in Werner-syndrome fibroblasts involve both p53-dependent and p53-independent mechanisms. Journal of Cell Science (JCS) 116 (7) , pp. 1349-57. 10.1242/jcs.00331
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Rees, Dafydd Aled ORCID: https://orcid.org/0000-0002-1165-9092, Lewis, Mark David, Lewis, Barbara Mary, Smith, Paul James, Scanlon, Maurice Francis and Ham, Jack 2002. Adenosine-regulated cell proliferation in pituitary folliculostellate and endocrine cells: differential roles for the A(1) and A(2B) adenosine receptors. Endocrinology 143 (6) , pp. 2427-2436. 10.1210/en.143.6.2427

Smith, Paul James, Blunt, Nicola, Wiltshire, Marie, Hoy, Terry, Teesdale-Spittle, P., Craven, M. R., Watson, J. V., Amos, W. B., Errington, Rachel Jane ORCID: https://orcid.org/0000-0002-8016-4376 and Patterson, L. H. 2000. Characteristics of a novel deep red/infrared fluorescent cell-permeant DNA probe, DRAQ5, in intact human cells analyzed by flow cytometry, confocal and multiphoton microscopy. Cytometry 40 (4) , pp. 280-291. 10.1002/1097-0320(20000801)40:4<280::AID-CYTO4>3.0.CO;2-7

Smith, Paul James, Wiltshire, Marie, Davies, Sharon, Patterson, Laurence H. and Hoy, Terry 1999. A novel cell permeant and far red-fluorescing DNA probe, DRAQ5, for blood cell discrimination by flow cytometry. Journal of Immunological Methods 229 (1-2) , pp. 131-139. 10.1016/S0022-1759(99)00116-7

Smith, Paul James, Desnoyers, R., Blunt, Nicola, Giles, Y., Patterson, L. H. and Watson, J. V. 1997. Flow cytometric analysis and confocal imaging of anticancer alkylaminoanthraquinones and their N-oxides in intact human cells using 647-nm krypton laser excitation. Cytometry 27 (1) , pp. 43-53. 10.1002/(SICI)1097-0320(19970101)27:1<43::AID-CYTO6>3.0.CO;2-M

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