Browse by Current Cardiff authors

Elphick, Emma H., Zavvos, Vasileios, Belcher, John, Topley, Nicholas, Chess, James A., Holmes, Clifford J., Davies, Simon J., Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342 and Lambie, Mark 2025. The role of peritoneal IL-6 in predicting patient survival on peritoneal dialysis. Kidney International Reports 10 (9) , pp. 3164-3173. 10.1016/j.ekir.2025.06.049

Giannoni, Eric, Sanchez, Guillem Sanchez, Verdebout, Isoline, Papadopoulou, Maria, Rezwani, Moosa, Ahmed, Raya, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Miners, Kelly L., McLaren, James E. ORCID: https://orcid.org/0000-0002-7021-5934, Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Eberl, Matthias ORCID: https://orcid.org/0000-0002-9390-5348, Study, Swiss Pediatric Sepsis, Agyeman, Philipp K.A., Schlapbach, Luregn and Vermijlen, David 2024. Sepsis shapes the human γδ TCR repertoire in an age- and pathogen-dependent manner. European Journal of Immunology 54 (10) , 2451190. 10.1002/eji.202451190

Lu, Yueh-An, Smith, Tanya, Deshpande, Sumukh, Liao, Chia-Te, Talabani, Bnar, Grigorieva, Irina, Mason, Anna, Andrews, Robert, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421 and Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342 2024. Sex-specific proximal tubular cell differentiation pathways identified by single-nucleus RNA sequencing. Scientific Reports 14 (1) , 24041. 10.1038/s41598-024-73102-7

Smith, Tanya, Zaidi, Aeliya, Brown, Charlotte Victoria Maynard, Pino-Chavez, Gilda, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978, Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342, Chavez, Rafael and Khalid, Usman 2024. Robust rat and mouse models of bilateral renal ischemia reperfusion injury. In Vivo 38 (3) , pp. 1049-1057. 10.21873/invivo.13538

Czubala, Magdalena A. ORCID: https://orcid.org/0000-0001-9881-1095, Jenkins, Robert H. ORCID: https://orcid.org/0000-0001-8500-9044, Gurney, Mark ORCID: https://orcid.org/0000-0003-1119-6638, Wallace, Leah, Cossins, Benjamin, Dennis, James, Rosas, Marcela ORCID: https://orcid.org/0000-0002-9442-9638, Andrews, Robert, Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342 and Taylor, Philip 2024. Tissue-specific transcriptional programming of macrophages controls the microRNA transcriptome targeting multiple functional pathways. Journal of Biological Chemistry 300 (5) , 107244. 10.1016/j.jbc.2024.107244

Varache, Mathieu ORCID: https://orcid.org/0000-0001-7166-2253, Rizzo, Siân, Sayers, Edward J. ORCID: https://orcid.org/0000-0002-2621-1119, Newbury, Lucy, Mason, Anna, Liao, Chia-Te, Chiron, Emilie, Bourdiec, Nathan, Jones, Adam, Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342, Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421, Jones, Arwyn T. ORCID: https://orcid.org/0000-0003-2781-8905, Thomas, David W. ORCID: https://orcid.org/0000-0001-7319-5820 and Ferguson, Elaine L. ORCID: https://orcid.org/0000-0002-0125-0234 2024. Dextrin conjugation to colistin inhibits its toxicity, cellular uptake and acute kidney injury in vivo. RSC Pharmaceutics 1 , pp. 68-79. 10.1039/D3PM00014A

Tam, Frederick W.K., Tumlin, James, Barratt, Jonathan, Rovin, Brad H., Roberts, Ian S.D., Roufosse, Candice, Cook, H. Terence, Bhangal, Gurjeet, Brown, Alison L., Busch, Martin, Dudhiya, Fayaz, Duliege, Anne-Marie, Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342, Gale, Daniel P., Huang, Chiu-Ching, Lai, Ping-Chin, Lee, Meng, Masuda, Esteban S., McAdoo, Stephen P., Rosenkranz, Alexander R., Sommerer, Claudia, Sunder-Plassmann, Gere, Szeto, Cheuk-Chun, Tang, Sydney C.W., Williamson, Don E., Willcocks, Lisa, Vielhauer, Volker, Kim, Min Jeong, Todd, Leslie, Zayed, Hany, Tong-Starksen, Sandra and Lafayette, Richard 2023. Randomized trial on the effect of an oral spleen tyrosine kinase inhibitor in the treatment of IgA nephropathy. Kidney International Reports 8 (12) , pp. 2546-2556. 10.1016/j.ekir.2023.09.024

Smith, Daniel A. ORCID: https://orcid.org/0000-0003-3145-3160, Redman, James E. ORCID: https://orcid.org/0000-0001-5492-2869, Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342 and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 2023. Identification and detection of microRNA kidney disease biomarkers in liquid biopsies. Current Opinion in Nephrology and Hypertension 32 (6) , pp. 515-521. 10.1097/MNH.0000000000000927

Cetin, Esra, Mazzarino, Morgane, González-Mateo, Guadalupe T., Kopytina, Valeria, Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978, Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342, López-Cabrera, Manuel, Labéta, Mario O. ORCID: https://orcid.org/0000-0001-5750-6983 and Raby, Anne-Catherine ORCID: https://orcid.org/0000-0002-5354-5835 2023. Calprotectin blockade inhibits long-term vascular pathology following peritoneal dialysis-associated bacterial infection. Frontiers in Cellular and Infection Microbiology 13 , 1285193. 10.3389/fcimb.2023.1285193

Roddick, Alistair J., Wonnacott, Alexa ORCID: https://orcid.org/0000-0002-0968-4248, Webb, David, Watt, Angela, Watson, Michael A., Staplin, Natalie, Riding, Alex, Lioudaki, Eirini, Kuverji, Apexa, Kossi, Mohsen El, Holmes, Patrick, Holloway, Matt, Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342, Carvalho, Chris, Burton, James O., Bhandari, Sunil, Herrington, William G. and Frankel, Andrew H. 2023. UK Kidney association clinical practice guideline: sodium-glucose co-transporter-2 (SGLT-2) inhibition in adults with kidney disease 2023 UPDATE. BMC Nephrology 24 (1) , 310. 10.1186/s12882-023-03339-3

Williams, Jennifer, Gilchrist, Mark, Strain, William David, Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342 and Shore, Angela 2022. 24-h Glycaemic profiles in peritoneal dialysis patients and non-dialysis controls with advanced kidney disease. Peritoneal Dialysis International 42 (5) , pp. 497-504. 10.1177/08968608211047787

Williams, Jennifer, Gilchrist, Mark, Strain, William David, Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342 and Shore, Angela 2022. An exploratory study of the relationship between systemic microcirculatory function and small solute transport in incident peritoneal dialysis patients. Peritoneal Dialysis International 42 (5) , pp. 513-521. 10.1177/08968608211047332

Zeni, Letizia, Norden, Anthony G. W., Prandi, Elena, Canepa, Carolina, Burling, Keith, Simpson, Katherine, Felappi, Barbara, Plebani, Alessandro, Cancarini, Giovanni, Ferraro, Pietro Manuel, Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342 and Unwin, Robert J. 2022. Exploration of a panel of urine biomarkers of kidney disease in two paediatric cohorts with Type 1 diabetes mellitus of differing duration. Diabetology and Metabolic Syndrome 14 (1) , 71. 10.1186/s13098-022-00839-4

Lu, Yueh-An, Liao, Chia-Te, Raybould, Rachel, Talabani, Bnar, Grigorieva, Irina, Szomolay, Barbara ORCID: https://orcid.org/0000-0002-5375-5533, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Andrews, Robert, Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421 and Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342 2021. Single-nucleus RNA sequencing identifies new classes of proximal tubular epithelial cells in kidney fibrosis. Journal of the American Society of Nephrology 32 (10) , pp. 2501-2516. 10.1681/ASN.2020081143

Newbury, Lucy J., Simpson, Kate, Khalid, Usman, John, Imogen, de Rivera, Lluís Bailach, Lu, Yueh-An, Lopez-Anton, Melisa, Watkins, William J. ORCID: https://orcid.org/0000-0003-3262-6588, Jenkins, Robert H. ORCID: https://orcid.org/0000-0001-8500-9044, Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342 and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 2021. miR-141 mediates recovery from acute kidney injury. Scientific Reports 11 (1) , 16499. 10.1038/s41598-021-94984-x

Smith, Daniel A. ORCID: https://orcid.org/0000-0003-3145-3160, Simpson, Kate, Lo Cicero, Matteo, Newbury, Lucy J., Nicholas, Philip, Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342, Caiger, Nigel, Redman, James E. ORCID: https://orcid.org/0000-0001-5492-2869 and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 2021. Detection of urinary microRNA biomarkers using diazo sulfonamide-modified screen printed carbon electrodes. RSC Advances 11 (31) , pp. 18832-18839. 10.1039/D0RA09874D

Khalid, Usman, Jenkins, Robert H. ORCID: https://orcid.org/0000-0001-8500-9044, Andrews, Robert, Pino-Chavez, Gilda, Cossins, Benjamin C., Chavez, Rafael, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 and Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342 2021. Determination of a microRNA signature of protective kidney ischemic preconditioning originating from proximal tubules. Scientific Reports 11 (1) , 9862. 10.1038/s41598-021-89195-3

Marchant, Vanessa, Tejera-Muñoz, Antonio, Marquez-Expósito, Laura, Rayego-Mateos, Sandra, Rodrigues-Diez, Raul R., Tejedor, Lucia, Santos-Sanchez, Laura, Egido, Jesús, Ortiz, Alberto, Valdivielso, Jose M., Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342, López-Cabrera, Manuel, Selgas, Rafael and Ruiz-Ortega, Marta 2020. IL-17A as a potential therapeutic target for patients on peritoneal dialysis. Biomolecules 10 (10) , 1361. 10.3390/biom10101361

Catar, Rusan A., Chen, Lei, Cuff, Simone M. ORCID: https://orcid.org/0000-0002-0546-3579, Kift-Morgan, Ann, Eberl, Matthias ORCID: https://orcid.org/0000-0002-9390-5348, Kettritz, Ralph, Kamhieh-Milz, Julian, Moll, Guido, Li, Qing, Zhao, Hongfan, Kawka, Edyta, Zickler, Daniel, Parekh, Gita, Davis, Paul, Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342, Dragun, Duska, Eckardt, Kai-Uwe, Jörres, Achim and Witowski, Janusz 2020. Control of neutrophil influx during peritonitis by transcriptional cross-regulation of chemokine CXCL1 by IL‐17 and IFN‐γ. Journal of Pathology 251 (2) , pp. 175-186. 10.1002/path.5438

Brook, Amy C., Jenkins, Robert H. ORCID: https://orcid.org/0000-0001-8500-9044, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Kift-Morgan, Ann, Raby, Anne-Catherine ORCID: https://orcid.org/0000-0002-5354-5835, Shephard, Alex P., Mariotti, Barbara, Cuff, Simone M. ORCID: https://orcid.org/0000-0002-0546-3579, Bazzoni, Flavia, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342 and Eberl, Matthias ORCID: https://orcid.org/0000-0002-9390-5348 2019. Neutrophil-derived miR-223 as local biomarker of bacterial peritonitis. Scientific Reports 9 , 10136. 10.1038/s41598-019-46585-y

Pottanat, Neha Dhingra, Brook, Amy C., Bartosova, Maria, Cortado, Hanna, Gupta, Sudipti, Li, Birong, Jackson, Ashley R., Vonau, Martin, Cohen, Shira, Ferrara, Maria, Ching, Christina B., Spencer, John David, Brauner, Annelie, Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342, Schmitt, Claus Peter, Eberl, Matthias ORCID: https://orcid.org/0000-0002-9390-5348, Ayoob, Rose and Becknell, Brian 2019. Analysis of the Ribonuclease a superfamily of antimicrobial peptides in patients undergoing chronic peritoneal dialysis. Scientific Reports 9 , -. 10.1038/s41598-019-44219-x

Khalid, Usman, Newbury, Lucy J., Simpson, Kate, Jenkins, Robert H. ORCID: https://orcid.org/0000-0001-8500-9044, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Bates, Lucy, Sheerin, Neil S., Chavez, Rafael and Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342 2019. A urinary microRNA panel that is an early predictive biomarker of delayed graft function following kidney transplant. Scientific Reports 9 , 3584. 10.1038/s41598-019-38642-3

Thomas, Melissa, Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342 and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 2018. Biogenesis, stabilization, and transport of microRNAs in kidney health and disease. Non-Coding RNA 4 (4) , p. 30. 10.3390/ncrna4040030

Beltrami, Cristina, Simpson, Kate, Jesky, Mark, Wonnacott, Alexa ORCID: https://orcid.org/0000-0002-0968-4248, Carrington, Christopher, Holmans, Peter ORCID: https://orcid.org/0000-0003-0870-9412, Newbury, Lucy, Jenkins, Robert ORCID: https://orcid.org/0000-0001-8500-9044, Ashdown, Thomas, Dayan, Colin ORCID: https://orcid.org/0000-0002-6557-3462, Satchell, Simon, Corish, Peter, Cockwell, Paul, Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342 and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 2018. Association of elevated urinary miR-126, miR-155, and miR-29b with diabetic kidney disease. American Journal of Pathology 188 (9) , pp. 1982-1992. 10.1016/j.ajpath.2018.06.006

Raby, Anne-Catherine ORCID: https://orcid.org/0000-0002-5354-5835, González-Mateo, Guadalupe T., Williams, Aled, Topley, Nicholas, Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342, López-Cabrera, Manuel and Labeta, Mario O. ORCID: https://orcid.org/0000-0001-5750-6983 2018. Targeting toll-like receptors with soluble toll-like receptor 2 prevents peritoneal dialysis solution-induced fibrosis. Kidney International 94 (2) , pp. 346-362. 10.1016/j.kint.2018.03.014

Wonnacott, Alexa ORCID: https://orcid.org/0000-0002-0968-4248, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 and Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342 2017. MicroRNAs as biomarkers in chronic kidney disease. Current Opinion in Nephrology and Hypertension 26 (6) , pp. 460-466. 10.1097/MNH.0000000000000356

Aufricht, Christoph, Beelen, Robert, Eberl, Matthias ORCID: https://orcid.org/0000-0002-9390-5348, Fischbach, Michel, Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342, Jörres, Achim, Kratochwill, Klaus, LópezCabrera, Manuel, Rutherford, Peter, Schmitt, Claus-Peter, Topley, Nicholas and Witowski, Janusz 2017. Biomarker research to improve clinical outcomes of peritoneal dialysis: consensus of the European Training and Research in Peritoneal Dialysis (EuTRiPD) network. Kidney International 92 (4) , pp. 824-835. 10.1016/j.kint.2017.02.037

Lopez-Anton, Melisa, Lambie, Mark, Lopez-Cabrera, Manuel, Schmitt, Claus P., Ruiz-Carpio, Vicente, Bartosova, Maria, Schaefer, Betti, Davies, Simon, Stone, Timothy ORCID: https://orcid.org/0000-0003-4591-9611, Jenkins, Robert ORCID: https://orcid.org/0000-0001-8500-9044, Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421, Topley, Nicholas, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 and Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342 2017. miR-21 promotes fibrogenesis in peritoneal dialysis. American Journal of Pathology 187 (7) , pp. 1537-1550. 10.1016/j.ajpath.2017.03.007

Zhang, Jingjing ORCID: https://orcid.org/0000-0002-8970-7568, Friberg, Ida M., Kift-Morgan, Ann, Parekh, Gita, Morgan, Matt P., Liuzzi, Anna Rita, Lin, Chan-Yu, Donovan, Kieron L., Colmont, Chantal S., Morgan, Peter H. ORCID: https://orcid.org/0000-0002-8555-3493, Davis, Paul, Weeks, Ian ORCID: https://orcid.org/0000-0002-6362-2929, Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342, Topley, Nicholas and Eberl, Matthias ORCID: https://orcid.org/0000-0002-9390-5348 2017. Machine-learning algorithms define pathogen-specific local immune fingerprints in peritoneal dialysis patients with bacterial infections. Kidney International 92 (1) , pp. 179-191. 10.1016/j.kint.2017.01.017

Lopez Anton, Melisa, Rudolf, Andras, Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467, Roger, Laureline, Robinson, Rhiannon, Witowski, Janusz, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 2017. Telomere length profiles in primary human peritoneal mesothelial cells are consistent with senescence. Mechanisms of Ageing and Development 164 , pp. 37-40. 10.1016/j.mad.2017.03.010

Liao, Chia-Te, Andrews, Robert, Wallace, Leah E., Khan, Mohd Wajid A., Kift-Morgan, Ann, Topley, Nicholas, Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342 and Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421 2017. Peritoneal macrophage heterogeneity is associated with different peritoneal dialysis outcomes. Kidney International 91 (5) , pp. 1088-1103. 10.1016/j.kint.2016.10.030

Raby, Anne-Catherine ORCID: https://orcid.org/0000-0002-5354-5835, Colmont, Chantal S., Kift-Morgan, Ann, Köhl, Jörg, Eberl, Matthias ORCID: https://orcid.org/0000-0002-9390-5348, Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342, Topley, Nicholas and Labeta, Mario O. ORCID: https://orcid.org/0000-0001-5750-6983 2017. Toll-like receptors 2 and 4 are potential therapeutic targets in peritoneal dialysis-associated fibrosis. Journal of the American Society of Nephrology 28 (2) , pp. 461-478. 10.1681/ASN.2015080923

Liao, Chia-Te, Rosas, Marcela ORCID: https://orcid.org/0000-0002-9442-9638, Davies, Luke C., Giles, Peter J. ORCID: https://orcid.org/0000-0003-3143-6854, Tyrrell, Victoria J., O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460, Topley, Nicholas, Humphreys, Ian R. ORCID: https://orcid.org/0000-0002-9512-5337, Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342, Jones, Simon A. ORCID: https://orcid.org/0000-0001-7297-9711 and Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421 2016. IL-10 differentially controls the infiltration of inflammatory macrophages and antigen-presenting cells during inflammation. European Journal of Immunology 46 (9) , pp. 2222-2232. 10.1002/eji.201646528

Liuzzi, Anna Rita, Kift-Morgan, Ann, Lopez-Anton, Melisa, Friberg, Ida M., Zhang, Jingjing ORCID: https://orcid.org/0000-0002-8970-7568, Brook, Amy C., Roberts, Gareth W., Donovan, Kieron L., Colmont, Chantal S., Toleman, Mark A., Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Johnson, David W., Topley, Nicholas, Moser, Bernhard ORCID: https://orcid.org/0000-0002-4354-4572, Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342 and Eberl, Matthias ORCID: https://orcid.org/0000-0002-9390-5348 2016. Unconventional human T cells accumulate at the site of infection in response to microbial ligands and induce local tissue remodeling. Journal of Immunology 197 (6) , pp. 2195-2207. 10.4049/jimmunol.1600990

Simpson, Katherine, Wonnacott, Alexa ORCID: https://orcid.org/0000-0002-0968-4248, Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342 and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 2016. MicroRNAs in diabetic nephropathy: from biomarkers to therapy. Current Diabetes Reports 16 (3) , 35. 10.1007/s11892-016-0724-8

Khalid, Usman, Ablorsu, Elijah, Szabo, Laszlo, Jenkins, Robert H. ORCID: https://orcid.org/0000-0001-8500-9044, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Chavez, Rafael and Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342 2016. MicroRNA-21 (miR-21) expression in hypothermic machine perfusate may be predictive of early outcomes in kidney transplantation. Clinical Transplantation 30 (2) , pp. 99-104. 10.1111/ctr.12679

Chavez, Rafael, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044, Nesargikar, Prabhu, Pino-Chavez, Gilda and Khalid, Usman 2016. Kidney ischaemia reperfusion injury in the rat: the EGTI scoring system as a valid and reliable tool for histological assessment. Journal of Histology and Histopathology 3 , 1. 10.7243/2055-091X-3-1

Beelen, Robert H. J., Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342, Rutherford, Peter and Witowski, Janusz 2016. Addressing peritoneal dialysis: in vitro PD models, in vivo rodent PD model, clinical biobanks, and underutilization of PD. BioMed Research International 2016 , 4964316. 10.1155/2016/4964316

Khalid, Usman, Jenkins, Robert H., Pino-Chavez, Gilda, Bowen, Timothy, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 and Chavez, Rafael 2015. A localized ischemic preconditioning regimen increases tumor necrosis factor a expression in a rat model of kidney ischemia-reperfusion injury. Experimental and Clinical Transplantation 13 (6) , pp. 535-542. 10.6002/ect.2015.0039

Nesargikar, Prabhu, Spiller, Brad, Jenkins, Robert ORCID: https://orcid.org/0000-0001-8500-9044, Khalid, Usman, Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342 and Chavez, Rafael 2015. Modulation of leukocytes and endothelium by anti-thymocyte globulin confers protection against renal ischemia reperfusion injury in rats. Transplant International 28 (54) , p. 61. 10.1111/tri.12700

Khalid, Usman, Ablorsu, Elijah, Szabo, Laszlo, Jenkins, Robert, Bowen, Timothy, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 and Chavez, Rafael 2015. Expression of mir-10a,-21,-29a,-221 and-429 in hypothermic machine perfusate predicts early outcomes in kidney transplantation [Abstract]. Transplant International 28 (S4) , p. 177. 10.1111/tri.12701

Khalid, Usman, Pino-Chavez, Gilda, Nesargikar, Prabhu, Jenkins, Robert, Bowen, Timothy, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 and Chavez, Rafael 2015. A new comprehensive scoring system is an accurate and robust tool for histological assessment of rat kidney IRI [Abstract]. Transplant International 28 (S4) , p. 260. 10.1111/tri.12701

Nesargikar, Prabhu, Pino-Chavez, Gilda, Spiller, Owen Bradley ORCID: https://orcid.org/0000-0002-9117-6911, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342, Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044 and Chavez, Rafael 2015. Single dose sCR1 attenuates renal ischemia reperfusion injury in rats despite early reconstitution of the complement system [Abstract]. Transplant International 28 (S4) , p. 62. 10.1111/tri.12700

Khalid, Usman, Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044, Simpson, Katherine, Ablorsu, Elijah, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 and Chavez, Rafael 2015. Urinary microrna expression predicts delayed graft function in kidney transplantation [Abstract]. Transplant International 28 (S4) , p. 367. 10.1111/tri.12702

Beltrami, Cristina, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Newbury, Lucy, Corish, Peter, Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 2015. Stabilization of urinary microRNAs by association with exosomes and argonaute 2 protein. Non-Coding RNA 1 (2) , pp. 151-166. 10.3390/ncrna1020151

Liao, Chia-Te, Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342, Topley, Nicholas and Taylor, Philip ORCID: https://orcid.org/0000-0003-0163-1421 2015. Deciphering the peritoneal mononuclear phagocyte system in mice: Steady state and inflammation [Poster abstract]. Nephrology Dialysis Transplantation 30 (iii) , iii265-. 10.1093/ndt/gfv180.25

Liao, Chia-Te, Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342, Topley, Nicholas and Taylor, Philip Russel ORCID: https://orcid.org/0000-0003-0163-1421 2015. Determining the identity and functional specialization of peritoneal mononuclear phagocytes in peritoneal dialysis patients. Nephrology Dialysis Transplantation 30 (S3) , iii264. 10.1093/ndt/gfv180.21

Jenkins, Robert ORCID: https://orcid.org/0000-0001-8500-9044, Liao, Chia-Te, Wallace, Leah, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Topley, Nicholas, Taylor, Philip ORCID: https://orcid.org/0000-0003-0163-1421 and Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342 2015. Microrna regulation of macrophage phenotype in peritoneal fibrosis. Nephrology Dialysis Transplantation 30 (iii262) 10.1093/ndt/gfv180.15

Khalid, Usman, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342 and Jenkins, Robert ORCID: https://orcid.org/0000-0001-8500-9044 2014. Acute kidney injury: a paradigm for miRNA regulation of the cell cycle. Biochemical Society Transactions 42 (4) , pp. 1219-1223. 10.1042/BST20140093

Rosas, Marcela ORCID: https://orcid.org/0000-0002-9442-9638, Davies, Luke C., Giles, Peter J. ORCID: https://orcid.org/0000-0003-3143-6854, Liao, Chia-Te, Kharfan, Bashar, Stone, Timothy C. ORCID: https://orcid.org/0000-0003-4591-9611, O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460, Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342, Jones, Simon A. ORCID: https://orcid.org/0000-0001-7297-9711 and Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421 2014. The transcription factor Gata6 links tissue macrophage phenotype and proliferative renewal. Science 344 (6184) , pp. 645-648. 10.1126/science.1251414

Jenkins, Robert H. ORCID: https://orcid.org/0000-0001-8500-9044, Davies, Luke C., Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421, Akiyama, Hideo, Cumbes, Bevan ORCID: https://orcid.org/0000-0001-8529-0040, Beltrami, Cristina, Carrington, Christopher P., Phillips, Aled O. ORCID: https://orcid.org/0000-0001-9744-7113, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 and Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342 2014. miR-192 induces G2/M growth arrest in aristolochic acid nephropathy. American Journal of Pathology 184 (4) , pp. 996-1009. 10.1016/j.ajpath.2013.12.028

Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342, Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153 and Jones, Gareth Wyn 2014. Interleukin-6 in renal disease and therapy. Nephrology Dialysis Transplantation 30 (4) , pp. 564-574. 10.1093/ndt/gfu233

Davies, Luke Cynlais, Rosas, Marcela ORCID: https://orcid.org/0000-0002-9442-9638, Jenkins, Stephen J., Liao, Chia-Te, Scurr, Martin John ORCID: https://orcid.org/0000-0002-4120-0688, Brombacher, Frank, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342, Allen, Judith E., Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 and Taylor, Philip Russel ORCID: https://orcid.org/0000-0003-0163-1421 2013. Distinct bone marrow-derived and tissue-resident macrophage lineages proliferate at key stages during inflammation. Nature Communications 4 , 1886. 10.1038/ncomms2877

Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044 and Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 2013. MicroRNAs, transforming growth factor Beta-1, and tissue fibrosis. The Journal of Pathology 229 (2) , pp. 274-285. 10.1002/path.4119

Bodenham, Tanya, Topley, Nicholas and Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 2012. Peritoneal fibrosis is mouse strain dependent. Nephrology Dialysis Transplantation 28 (8) , pp. 1966-1969. 10.1093/ndt/gfs446

Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044, Martin, John, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 and Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 2012. Transforming growth factor β1 represses proximal tubular cell microRNA-192 expression through decreased hepatocyte nuclear factor DNA binding. Biochemical Journal 443 (2) , pp. 407-416. 10.1042/BJ20111861

Beltrami, Cristina, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 2012. Analysis of urinary microRNAs in chronic kidney disease. Biochemical Society Transactions 40 (4) , pp. 875-879. 10.1042/BST20120090

Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044, Martin, John, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 and Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 2012. Pleiotropy of microRNA-192 in the kidney. Biochemical Society Transactions 40 (4) , pp. 762-767. 10.1042/BST20120085

Martin, John, Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044, Bennagi, Rasha, Krupa, Aleksandra, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 and Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 2011. Post-transcriptional regulation of transforming growth factor beta-1 by microrna-744. PLoS ONE 6 (10) , e25044. 10.1371/journal.pone.0025044

Davies, Luke Cynlais, Rosas, Marcela ORCID: https://orcid.org/0000-0002-9442-9638, Smith, Paul James, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 and Taylor, Philip Russel ORCID: https://orcid.org/0000-0003-0163-1421 2011. A quantifiable proliferative burst of tissue macrophages restores homeostatic macrophage populations after acute inflammation. European Journal of Immunology 41 (8) , pp. 2155-2164. 10.1002/eji.201141817

Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044 and Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 2011. BMP-6 emerges as a potential major regulator of fibrosis in the kidney [Commentary]. American Journal of Pathology 178 (3) , pp. 964-965. 10.1016/j.ajpath.2010.12.010

Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044, Bennagi, Rasha, Martin, John, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113, Redman, James Edward ORCID: https://orcid.org/0000-0001-5492-2869 and Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 2010. A conserved stem loop motif in the 5'Untranslated Region regulates transforming growth factor-β1 translation. PLoS One 5 (8) , e12283. 10.1371/journal.pone.0012283

Krupa, Aleksandra, Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044, Luo, Dong Dong, Lewis, Aled G., Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 and Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 2010. Loss of microRNA-192 promotes fibrogenesis in diabetic nephropathy. Journal of the American Society of Nephrology 21 (3) , pp. 438-447. 10.1681/ASN.2009050530

Luo, Dong Dong, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 and Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 2010. Bone morphogenetic protein-7 inhibits proximal tubular epithelial cell smad3 signaling via increased SnoN expression. American Journal of Pathology 176 (3) , pp. 1139-1147. 10.2353/ajpath.2010.090459

Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 and Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 2010. BMP-7 stops TGF-β in peritoneal fibrosis. Nephrology Dialysis Transplantation 25 (4) , pp. 1036-1038. 10.1093/ndt/gfq032

Luo, Dong Dong, Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 and Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 2009. Interleukin-1 beta regulates proximal tubular cell transforming growth factor beta-1 signalling. Nephrology Dialysis Transplantation 24 (9) , pp. 2655-2665. 10.1093/ndt/gfp208

Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 and Topley, Nicholas 2009. Altering peritoneal membrane function: removing the GAG? Nephrology Dialysis Transplantation 24 (11) , pp. 3271-3273. 10.1093/ndt/gfp440

Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342, Phillips, Aled Owen ORCID: https://orcid.org/0000-0001-9744-7113, Zhang, Xiao Liang, van Roeyen, C. R., Muehlenberg, P., En-Nia, A. and Mertens, P. R. 2008. Y-box protein-1 controls transforming growth factor-β1 translation in proximal tubular cells. Kidney International 73 (6) , pp. 724-732. 10.1038/sj.ki.5002719

Zhang, M., Lee, C., Luo, D. D., Krupa, A., Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2007. Polarity of response to transforming growth factor-beta1 in proximal tubular epithelial cells is regulated by beta-catenin. Journal of Biological Chemistry 282 (39) , pp. 28639-28647. 10.1074/jbc.m700594200

Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 2007. SMAD7: at the interface of TGF-beta and proinflammatory signalling[review]. Peritoneal Dialysis International 27 (5) , pp. 523-525.

Zhang, M., Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2006. ERK, p38, and Smad signaling pathways differentially regulate transforming growth factor-beta1 autoinduction in proximal tubular epithelial cells. American Journal of Pathology 169 (4) , pp. 1282-1293. 10.2353/ajpath.2006.050921

Monslow, Jamie, Williams, John David, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342, Michael, Daryn Robert, Foka, Pelagia, Kift-Morgan, Ann Patricia, Luo, Dong Dong, Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153, Craig, Kathrine Jane, Topley, Nicholas, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711, Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 2006. Sp1 and Sp3 mediate constitutive transcription of the human hyaluronan synthase 2 gene. The Journal of Biological Chemistry 281 (26) , pp. 18043-18050. 10.1074/jbc.M510467200

Matsumoto, N., Riley, Stephen George, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342, Al-Assaf, S., Ishimura, E., Wolever, T., Phillips, G. O. and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2006. Butyrate modulates TGF-beta1 generation and function: potential renal benefit for Acacia(sen) SUPERGUM (gum arabic)? Kidney International 69 (2) , pp. 257-65. 10.1038/sj.ki.5000028

Ito, Takafumi, Williams, John David, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2004. Hyaluronan regulates transforming growth factor-beta1 receptor compartmentalization. The Journal of Biological Chemistry 279 (24) , pp. 25326-25332. 10.1074/jbc.M403135200

Ito, T., Williams, J. D., Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342 and Phillips, Aled Owen ORCID: https://orcid.org/0000-0001-9744-7113 2004. Hyaluronan attenuates transforming growth factor-beta1-mediated signaling in renal proximal tubular epithelial cells. American Journal of Pathology 164 (6) , pp. 1979-1988. 10.1016/s0002-9440(10)63758-3

Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342, Brunskill, Nigel, Ito, Takafumi and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2003. Long-term exposure of proximal tubular epithelial cells to glucose induces transforming growth factor-beta 1 synthesis via an autocrine PDGF loop. American Journal of Pathology 163 (6) , pp. 2565-2574.

Tian, Ya-Chung, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342, Attisano, Liliana and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2003. TGF-beta1-mediated alterations of renal proximal tubular epithelial cell phenotype. American Journal of Physiology - Renal Physiology 285 (1) , F130-142. 10.1152/ajprenal.00408.2002

Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 and Wakefield, Lalage 2002. Independent regulation of transforming growth factor-beta1 transcription and translation by glucose and platelet-derived growth factor. American Journal of Pathology 161 (3) , pp. 1039-1049.

Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 and Jibani, M. 2000. An unexpected and serious complication of treatment with the atypical antipsychotic drug clozapine. Clinical Nephrology 54 (1) , pp. 78-80.