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Identification and detection of microRNA kidney disease biomarkers in liquid biopsies.
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Martin, John, Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044, Bennagi, Rasha, Krupa, Aleksandra, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 and Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 2011. Post-transcriptional regulation of transforming growth factor beta-1 by microrna-744. PLoS ONE 6 (10) , e25044. 10.1371/journal.pone.0025044 |
Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044 and Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 2011. BMP-6 emerges as a potential major regulator of fibrosis in the kidney [Commentary]. American Journal of Pathology 178 (3) , pp. 964-965. 10.1016/j.ajpath.2010.12.010 |
Krupa, Aleksandra, Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044, Luo, Dong Dong, Lewis, Aled G., Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 and Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 2010. Loss of microRNA-192 promotes fibrogenesis in diabetic nephropathy. Journal of the American Society of Nephrology 21 (3) , pp. 438-447. 10.1681/ASN.2009050530 |
Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 and Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 2010. BMP-7 stops TGF-β in peritoneal fibrosis. Nephrology Dialysis Transplantation 25 (4) , pp. 1036-1038. 10.1093/ndt/gfq032 |
Luo, Dong Dong, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 and Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 2010. Bone morphogenetic protein-7 inhibits proximal tubular epithelial cell smad3 signaling via increased SnoN expression. American Journal of Pathology 176 (3) , pp. 1139-1147. 10.2353/ajpath.2010.090459 |
Luo, Dong Dong, Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 and Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 2009. Interleukin-1 beta regulates proximal tubular cell transforming growth factor beta-1 signalling. Nephrology Dialysis Transplantation 24 (9) , pp. 2655-2665. 10.1093/ndt/gfp208 |
Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 and Topley, Nicholas 2009. Altering peritoneal membrane function: removing the GAG? Nephrology Dialysis Transplantation 24 (11) , pp. 3271-3273. 10.1093/ndt/gfp440 |
Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342, Phillips, Aled Owen ORCID: https://orcid.org/0000-0001-9744-7113, Zhang, Xiao Liang, van Roeyen, C. R., Muehlenberg, P., En-Nia, A. and Mertens, P. R. 2008. Y-box protein-1 controls transforming growth factor-β1 translation in proximal tubular cells. Kidney International 73 (6) , pp. 724-732. 10.1038/sj.ki.5002719 |
Zhang, M., Lee, C., Luo, D. D., Krupa, A., Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2007. Polarity of response to transforming growth factor-beta1 in proximal tubular epithelial cells is regulated by beta-catenin. Journal of Biological Chemistry 282 (39) , pp. 28639-28647. 10.1074/jbc.m700594200 |
Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 2007. SMAD7: at the interface of TGF-beta and proinflammatory signalling[review]. Peritoneal Dialysis International 27 (5) , pp. 523-525. |
Zhang, M., Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2006. ERK, p38, and Smad signaling pathways differentially regulate transforming growth factor-beta1 autoinduction in proximal tubular epithelial cells. American Journal of Pathology 169 (4) , pp. 1282-1293. 10.2353/ajpath.2006.050921 |
Monslow, Jamie, Williams, John David, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342, Michael, Daryn Robert, Foka, Pelagia, Kift-Morgan, Ann Patricia, Luo, Dong Dong, Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153, Craig, Kathrine Jane, Topley, Nicholas, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711, Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 2006. Sp1 and Sp3 mediate constitutive transcription of the human hyaluronan synthase 2 gene. The Journal of Biological Chemistry 281 (26) , pp. 18043-18050. 10.1074/jbc.M510467200 |
Matsumoto, N., Riley, Stephen George, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342, Al-Assaf, S., Ishimura, E., Wolever, T., Phillips, G. O. and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2006. Butyrate modulates TGF-beta1 generation and function: potential renal benefit for Acacia(sen) SUPERGUM (gum arabic)? Kidney International 69 (2) , pp. 257-65. 10.1038/sj.ki.5000028 |
Ito, Takafumi, Williams, John David, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2004. Hyaluronan regulates transforming growth factor-beta1 receptor compartmentalization. The Journal of Biological Chemistry 279 (24) , pp. 25326-25332. 10.1074/jbc.M403135200 |
Ito, T., Williams, J. D., Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342 and Phillips, Aled Owen ORCID: https://orcid.org/0000-0001-9744-7113 2004. Hyaluronan attenuates transforming growth factor-beta1-mediated signaling in renal proximal tubular epithelial cells. American Journal of Pathology 164 (6) , pp. 1979-1988. 10.1016/s0002-9440(10)63758-3 |
Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342, Brunskill, Nigel, Ito, Takafumi and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2003. Long-term exposure of proximal tubular epithelial cells to glucose induces transforming growth factor-beta 1 synthesis via an autocrine PDGF loop. American Journal of Pathology 163 (6) , pp. 2565-2574. |
Tian, Ya-Chung, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342, Attisano, Liliana and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2003. TGF-beta1-mediated alterations of renal proximal tubular epithelial cell phenotype. American Journal of Physiology - Renal Physiology 285 (1) , F130-142. 10.1152/ajprenal.00408.2002 |
Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 and Wakefield, Lalage 2002. Independent regulation of transforming growth factor-beta1 transcription and translation by glucose and platelet-derived growth factor. American Journal of Pathology 161 (3) , pp. 1039-1049. |
Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 and Jibani, M. 2000. An unexpected and serious complication of treatment with the atypical antipsychotic drug clozapine. Clinical Nephrology 54 (1) , pp. 78-80. |