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Number of items: 17.

Baldwin, Alex G. ORCID: https://orcid.org/0000-0002-7126-5220, Foley, David W. ORCID: https://orcid.org/0000-0001-8449-4754, Collins, Ross, Lee, Hyunah, Jones, D. Heulyn, Wahab, Ben, Waters, Loren, Pedder, Josephine, Paine, Marie, Feng, Gui Jie, Privitera, Lucia, Ashall-Kelly, Alexander, Thomas, Carys, Gillespie, Jason A., Schino, Lauramariú, Belelli, Delia, Rocha, Cecilia, Maussion, Gilles, Krahn, Andrea I., Durcan, Thomas M., Elkins, Jonathan M., Lambert, Jeremy J., Atack, John R. ORCID: https://orcid.org/0000-0002-3410-791X and Ward, Simon E. ORCID: https://orcid.org/0000-0002-8745-8377 2025. Discovery of MDI-114215: A potent and selective LIMK inhibitor to treat fragile X syndrome. Journal of Medicinal Chemistry 68 (1) , pp. 719-752. 10.1021/acs.jmedchem.4c02694
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Collins, Ross, Lee, Hyunah, Jones, Dyfyr, Elkins, Jonathan M., Gillespie, Jason A., Thomas, Carys, Baldwin, Alex G. ORCID: https://orcid.org/0000-0002-7126-5220, Jones, Kimberley, Waters, Loren, Paine, Marie, Atack, John R. ORCID: https://orcid.org/0000-0002-3410-791X, Ward, Simon E. ORCID: https://orcid.org/0000-0002-8745-8377, Grubisha, Olivera ORCID: https://orcid.org/0000-0003-1067-1230 and Foley, David W. ORCID: https://orcid.org/0000-0001-8449-4754 2022. Comparative analysis of small-molecule limk1/2 inhibitors: chemical synthesis, biochemistry, and cellular activity. Journal of Medicinal Chemistry 10.1021/acs.jmedchem.2c00751
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Bong Lee, Jong, Zang, Xiaowei, Zgair, Atheer, Qian Ooi, Ting, Foley, David W ORCID: https://orcid.org/0000-0001-8449-4754, Voronin, Gregory, Kagan, Leonid, Soukarieh, Fadi, Gao, Rui, Shao, Hao, Tying Soh, Wan, Hwan Kim, Tae, Gi Kim, Min, Yun, Hwi-yeol, Wilson, Anthony J., Fischer, Peter M. and Gershkovich, Pavel 2021. Postprandial administration but not controlled release in the colon increases oral bioavailability of DF030263, a promising drug candidate for chronic lymphocytic leukemia. European Journal of Pharmaceutics and Biopharmaceutics 165 , pp. 106-112. 10.1016/j.ejpb.2021.05.006
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Shao, Hao, Foley, David ORCID: https://orcid.org/0000-0001-8449-4754, Huang, Shiliang, Abbas, Abdullahi, Lam, Frankie, Gershkovich, Pavel, Bradshaw, Tracey, Pepper, Chris, Fischer, Peter and Wang, Shudong 2021. Structure-based design of highly selective 2,4,5-trisubstituted pyrimidine CDK9 inhibitors as anti-cancer agents. European Journal of Medicinal Chemistry 214 , 113244. 10.1016/j.ejmech.2021.113244
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Willetts, Steffan and Foley, David W. ORCID: https://orcid.org/0000-0001-8449-4754 2020. True or false? challenges and recent highlights in the development of aspirin prodrugs. European Journal of Medicinal Chemistry 192 , 112200. 10.1016/j.ejmech.2020.112200
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Bell, Mark, Foley, David ORCID: https://orcid.org/0000-0001-8449-4754, Naylor, Claire, Wood, Gavin, Robinson, Colin, Riley, Jennifer, Epemolu, Ola, Ellis, Lucy, Scullion, Paul, Shishikura, Yoko, Osuna-Cabello, Maria, Ferguson, Liam, Pinto, Erika, Fletcher, Daniel, Katz, Elad, McLean, W. H. Irwin, Wyatt, Paul, Read, Kevin D and Woodland, Andrew 2019. Discovery of soft-drug topical tool modulators of Sphingosine-1-phosphate Receptor 1 (S1PR1). ACS Medicinal Chemistry Letters 10 (3) , pp. 341-347. 10.1021/acsmedchemlett.8b00616
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Bell, Mark, Foley, David ORCID: https://orcid.org/0000-0001-8449-4754, Naylor, Claire, Robinson, Colin, Riley, Jennifer, Epemolu, Ola, Scullion, Paul, Shishikura, Yoko, Katz, Elad, McLean, W. H. Irwin, Wyatt, Paul, Read, Kevin D. and Woodland, Andrew 2018. Discovery of super soft-drug modulators of sphingosine-1-phosphate receptor 1. Bioorganic & Medicinal Chemistry Letters 28 (19) , pp. 3255-3259. 10.1016/j.bmcl.2018.07.044
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Foley, David W. ORCID: https://orcid.org/0000-0001-8449-4754, Pathak, Ravindra B., Phillips, Theresa R., Wilson, Gayle L., Bailey, Patrick D., Pieri, Myrtani, Senan, Anish and Meredith, David 2018. Thiodipeptides targeting the intestinal oligopeptide transporter as a general approach to improving oral drug delivery. European Journal of Medicinal Chemistry 156 , pp. 180-189. 10.1016/j.ejmech.2018.06.064
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Pearson, Lesley-Anne and Foley, David William ORCID: https://orcid.org/0000-0001-8449-4754 2017. Communicating our science to our customers: drug discovery in five simple experiments. ACS Medicinal Chemistry Letters 8 (2) , pp. 143-144. 10.1021/acsmedchemlett.7b00015
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Foley, David W. ORCID: https://orcid.org/0000-0001-8449-4754, Bermudez, Isabel, Bailey, Patrick D. and Meredith, David 2016. A cyclosporine derivative is a substrate of the oligopeptide transporter PepT1. MedChemComm 7 (5) , pp. 999-1002. 10.1039/C5MD00575B

Assefnia, Shahin, Dakshanamurthy, Sivanesan, Auvil, Jaime M. Guidry, Hampel, Constanze, Anastasiadis, Panos Z., Kallakury, Bhaskar, Uren, Aykut, Foley, David W. ORCID: https://orcid.org/0000-0001-8449-4754, Brown, Milton L., Shapiro, Lawrence, Brenner, Michael, Haigh, David and Byers, Stephen W. 2015. Cadherin-11 in poor prognosis malignancies and rheumatoid arthritis: common target, common therapies. Oncotarget 5 (6) , pp. 1458-1474. 10.18632/oncotarget.1538

Shao, Hao, Shi, Shenhua, Foley, David W. ORCID: https://orcid.org/0000-0001-8449-4754, Lam, Frankie, Abbas, Abdullah Y., Liu, Xiangrui, Huang, Shiliang, Jiang, Xiangrui, Baharin, Nadiah, Fischer, Peter M. and Wang, Shudong 2013. Synthesis, structure-activity relationship and biological evaluation of 2,4,5-trisubstituted pyrimidine CDK inhibitors as potential anti-tumour agents. European Journal of Medicinal Chemistry 70 , pp. 447-455. 10.1016/j.ejmech.2013.08.052

Shao, H., Shi, S., Huang, S, Hole, A., Abbas, A., Baumli, S., Liu, X., Lam, F., Foley, David ORCID: https://orcid.org/0000-0001-8449-4754, Fischer, P., Noble, M., Endicott, J., Pepper, Christopher John and Wang, S. 2013. Substituted 4-(Thiazol-5-yl)-2-(phenylamino)pyrimidines are highly active CDK9 inhibitors: synthesis, X-ray crystal structures, structure activity relationship, and anticancer activities. Journal of Medicinal Chemistry 56 (3) , pp. 640-659. 10.1021/jm301475f

Foley, David ORCID: https://orcid.org/0000-0001-8449-4754, Rajamanickam, Jeyaganesh, Bailey, Patrick and Meredith, David 2010. Bioavailability through PepT1: the role of computer modelling in intelligent drug design. Current Computer Aided-Drug Design 6 (1) , pp. 68-78. 10.2174/157340910790980133

Mace, Oliver J., Lister, Norma, Morgan, Emma, Shepherd, Emma, Affleck, Julie, Helliwell, Philip, Bronk, John R., Kellett, George L., Meredith, David, Boyd, Richard, Pieri, Myrtani, Bailey, Pat D., Pettcrew, Rachel and Foley, David ORCID: https://orcid.org/0000-0001-8449-4754 2009. An energy supply network of nutrient absorption coordinated by calcium and T1R taste receptors in rat small intestine. The Journal of Physiology 587 (1) , pp. 195-210. 10.1113/jphysiol.2008.159616

Foley, David ORCID: https://orcid.org/0000-0001-8449-4754, Bailey, Patrick, Pieri, Myrtani and Meredith, David 2009. Targeting ketone drugs towards transport by the intestinal peptide transporter, PepT1. Organic & Biomolecular Chemistry 7 (6) , pp. 1064-1067. 10.1039/b818606e

Foley, David ORCID: https://orcid.org/0000-0001-8449-4754, Pieri, Myrtani, Pettecrew, Rachel, Price, Richard, Miles, Stephen, Lam, Ho Kam, Bailey, Patrick and Meredith, David 2009. The in vitro transport of model thiodipeptide prodrugs designed to target the intestinal oligopeptide transporter, PepT1. Organic & Biomolecular Chemistry 7 (18) , pp. 3652-3656. 10.1039/b909221h

This list was generated on Fri Jun 20 10:28:42 2025 BST.


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