Clarke, Zoe L., Moat, Stuart James, Miller, Alastair L., Randall, Michael D., Lewis, Malcolm John and Lang, Derek 2006. Differential effects of low and high dose folic acid on endothelial dysfunction in a murine model of mild hyperhomocysteinaemia. European Journal of Pharmacology 551 (1-3) , pp. 92-97. 10.1016/j.ejphar.2006.08.085 |
Moat, Stuart James, Madhavan, Anil Kumar, Taylor, Sarah Yvonne, Payne, Nichola, Allen, R. H., Stabler, Sally P., Goodfellow, Jonathan, McDowell, Ian Frederick, Lewis, Malcolm John and Lang, Derek 2006. High- but not low-dose folic acid improves endothelial function in coronary artery disease. European Journal Of Clinical Investigation 36 (12) , pp. 850-859. 10.1111/j.1365-2362.2006.01739.x |
Moat, Stuart James, Clarke, Zoe L., Madhavan, Anil Kumar, Lewis, Malcolm John and Lang, Derek 2006. Folic acid reverses endothelial dysfunction induced by inhibition of tetrahydrobiopterin biosynthesis. European Journal of Pharmacology 530 (3) , pp. 250-258. 10.1016/j.ejphar.2005.11.047 |
Williams, Paula Claire, Coffey, Marcus Jonathan, Coles, Barbara, Sanchez, Stephanie, Morrow, Jason D., Cockcroft, John Ronald, Lewis, Malcolm John and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2005. In vivo aspirin supplementation inhibits nitric oxide consumption by human platelets. Blood 106 (8) , pp. 2737-2743. 10.1182/blood-2005-02-0664 |
Doshi, Sagar Navin, McDowell, Ian Frederick, Goodfellow, Jonathan, Stabler, Sally, Boger, Rainer, Allen, Robert, Newcombe, Robert Gordon ORCID: https://orcid.org/0000-0003-4400-8867, Lewis, Malcolm John and Moat, Stuart James 2005. Relationship between S-adenosylmethionine, S-adenosylhomocysteine, asymmetric dimethylarginine, and endothelial function in healthy human subjects during experimental hyper- and hypohomocysteinemia. Metabolism 54 (3) , pp. 351-360. 10.1016/j.metabol.2004.09.015 |
Clark, Stephen Robert ORCID: https://orcid.org/0000-0001-5907-9671, Coffey, Marcus Jonathan, McLean, Rhona Murray, Collins, Peter William ORCID: https://orcid.org/0000-0002-6410-1324, Lewis, Malcolm John, Cross, Andrew R. and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2002. Characterization of nitric oxide consumption pathways by normal, chronic granulomatous disease and myeloperoxidase-deficient human neutrophils. The Journal of Immunology 169 (10) , pp. 5889-5896. |
Coles, Barbara, Bloodsworth, Allison, Clark, Stephen Robert ORCID: https://orcid.org/0000-0001-5907-9671, Lewis, Malcolm John, Cross, Andrew R., Freeman, Bruce A. and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2002. Nitrolinoleate inhibits superoxide generation, degranulation, and integrin expression by human neutrophils: novel antiinflammatory properties of nitric oxide-derived reactive species in vascular cells. Circulation Research 91 (5) , pp. 375-381. 10.1161/01.RES.0000032114.68919.EF |
Pullin, C. H., Bonham, James R., McDowell, Ian Frederick, Lee, P. J., Powers, H. J., Wilson, John Fawcett, Lewis, Malcolm John and Moat, Stuart James 2002. Vitamin C therapy ameliorates vascular endothelial dysfunction in treated patients with homocystinuria. Journal of Inherited Metabolic Disease 25 (2) , pp. 107-118. 10.1023/A:1015672625913 |
Doshi, Sagar Navin, McDowell, Ian Frederick, Moat, Stuart James, Payne, Nicola, Durrant, Hilary J., Lewis, Malcolm John and Goodfellow, Jonathan 2002. Folic acid improves endothelial function in coronary artery disease via mechanisms largely independent of homocysteine lowering. Circulation 105 (1) , pp. 22-26. 10.1161/hc0102.101388 |
Ashfield-Watt, Pauline Annie L., Pullin, C. H., Whiting, Jane Margaret Anne, Clark, Zoe Elizabeth, Moat, Stuart James, Newcombe, Robert Gordon ORCID: https://orcid.org/0000-0003-4400-8867, Burr, Michael Leslie, Lewis, Malcolm John, Powers, H. J. and McDowell, Ian Frederick 2002. Methylenetetrahydrofolate reductase 677CT genotype modulates homocysteine responses to a folate-rich diet or a low-dose folic acid supplement: a randomized controlled trial. American Journal of Clinical Nutrition 76 (1) , pp. 180-186. |
Coffey, Marcus Jonathan, Natarajan, Rama, Chumley, Philip H., Coles, Barbara, Thimmalapura, Pushpa-Rekha, Nowell, Mari Ann, Kühn, Hartmut, Lewis, Malcolm John, Freeman, Bruce A. and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2001. Catalytic consumption of nitric oxide by 12/15- lipoxygenase: inhibition of monocyte soluble guanylate cyclase activation. Proceedings of the National Academy of Sciences of the United States of America (PNAS) ISSN 1091-6490 98 (14) , pp. 8006-8011. 10.1073/pnas.141136098 |
Doshi, Sagar Navin, McDowell, Ian Frederick, Moat, Stuart, Lang, Derek, Newcombe, Robert ORCID: https://orcid.org/0000-0003-4400-8867, Kredan, Mahmud B., Lewis, Malcolm John and Goodfellow, Jonathan 2001. Folate improves endothelial function in coronary artery disease: an effect mediated by reduction of intracellular superoxide? Arteriosclerosis Thrombosis and Vascular Biology 21 (7) , pp. 1196-1202. 10.1161/hq0701.092000 |
Fisher, M., Liu, B., Glennon, P. E., Southgate, K. M., Sale, E. M., Sale, G. J., Lewis, Malcolm John and Groves, P. H. 2001. Downregulation of the ERK 1 and 2 mitogen activated protein kinases using antisense oligonucleotides inhibits proliferation of porcine vascular smooth muscle cells. Atherosclerosis 156 (2) , pp. 289-295. 10.1016/S0021-9150(00)00656-0 |
Pullin, Catherine H., Ashfield-Watt, Pauline Annie Lorraine, Burr, Michael Leslie, Clark, Zoe Elizabeth, Lewis, Malcolm John, Moat, Stuart James, Newcombe, Robert Gordon ORCID: https://orcid.org/0000-0003-4400-8867, Powers, Hilary J., Whiting, Jenny M. and McDowell, Ian Frederick 2001. Optimization of dietary folate or low-dose folic acid supplements lower homocysteine but do not enhance endothelial function in healthy adults, irrespective of the methylenetetrahydrofolate reductase (C677T) genotype. Journal of the American College of Cardiology 38 (7) , pp. 1799-1805. 10.1016/S0735-1097(01)01668-0 |
Bellamy, M. F., Goodfellow, J., Tweddel, A. C., Dunstan, Frank David John ORCID: https://orcid.org/0000-0002-1043-5281, Lewis, Malcolm John and Henderson, A. H. 1998. Syndrome X and endothelial dysfunction. Cardiovascular Research 40 (2) , pp. 410-417. 10.1016/s0008-6363(98)00184-9 |
Williams, John, Lang, Derek, Warden-Smith, Jeremy and Lewis, Malcolm John 1993. Plasma L-arginine levels in a rabbit model of hypercholesterolaemia. Biochemical Pharmacology 46 (11) , pp. 2097-2099. 10.1016/0006-2952(93)90653-E |
Lang, Derek, Warden-Smith, Jeremy and Lewis, Malcolm John 1993. Induction of a calcium-independent NO synthase by hypercholesterolaemia in the rabbit. British Journal of Pharmacology 108 (2) , pp. 290-292. |
Warden-Smith, Jeremy, Radomski, M. W., Schulz, R., Moncada, S. and Lewis, Malcolm John 1993. Porcine ventricular endocardial cells in culture express the inducible form of nitric oxide synthase. British Journal of Pharmacology 108 (4) , pp. 1107-1110. |
Henderson, Andrew H., Lewis, Malcolm John, Shah, Ajay M. and Warden-Smith, Jeremy 1992. Endothelium, endocardium, and cardiac contraction. Cardiovascular Research 26 (4) , pp. 305-308. 10.1093/cvr/26.4.305 |
Warden-Smith, Jeremy, Shah, Ajay M., Fort, S and Lewis, Malcolm John 1992. The influence of endocardial endothelium on myocardial contraction. Trends in Pharmacological Sciences 13 (3) , pp. 113-116. 10.1016/0165-6147(92)90040-D |
Warden-Smith, Jeremy, Shah, Ajay M. and Lewis, Malcolm John 1991. Factors released from endocardium of the ferret and pig modulate myocardial contraction. Journal of Physiology 439 , pp. 1-14. |
Schulz, R., Warden-Smith, Jeremy, Lewis, Malcolm John and Moncada, S. 1991. Nitric oxide synthase in cultured endocardial cells of the pig. British Journal of Pharmacology 104 (1) , pp. 21-24. |
Lewis, Malcolm John, Shah, Ajay M., Warden-Smith, Jeremy and Henderson, Andrew H. 1990. Does endocardium modulate myocardial contractile performance? Cardioscience 1 (2) , pp. 83-87. |
Hogan, J. C., Warden-Smith, Jeremy, Richards, A. C. and Lewis, Malcolm John 1989. Atrial natriuretic peptide inhibits the release of endothelium-derived relaxing factor from blood vessels of the rabbit. European Journal of Pharmacology 165 (1) , pp. 129-134. 10.1016/0014-2999(89)90778-4 |
Mulligan, I. P., Fraser, Alan Gordon, Lewis, Malcolm John and Henderson, A. H. 1989. Effects of enalapril on myocardial noradrenaline overflow during exercise in patients with chronic heart failure. British Heart Journal 61 (1) , pp. 23-28. 10.1136/hrt.61.1.23 |
Salek, Mir-saeed, Luscombe, David Keith, Walker, Stuart, Grob, P. R., Vandenburg, M. J. and Lewis, Malcolm John 1988. Cardiovascular-disease and quality of life [Abstract]. British Journal of Clinical Pharmacology 26 (5) , 628P-628P. |
Evans, H. G., Warden-Smith, Jeremy and Lewis, Malcolm John 1988. Release of endothelium-derived relaxing factor is inhibited by 8-bromo-cyclic guanosine monophosphate. Journal of Cardiovascular Pharmacology 12 (6) , pp. 672-677. |
Martin, William, Warden-Smith, Jeremy, Lewis, Malcolm John and Henderson, Andrew H. 1988. Evidence that inhibitory factor extracted from bovine retractor penis is nitrite, whose acid-activated derivative is stabilized nitric oxide. British Journal of Pharmacology 93 (3) , pp. 579-586. |
Mulligan, I. P., Fraser, Alan Gordon, Tirlapur, V., Lewis, Malcolm John, Newcombe, Robert Gordon ORCID: https://orcid.org/0000-0003-4400-8867 and Henderson, A. 1988. A randomized cross-over study of enalapril in congestive heart failure: haemodynamic and hormonal effects during rest and exercise. European Journal of Clinical Pharmacology 34 (4) , pp. 323-331. 10.1007/bf00542431 |
Chappell, S. P., Morgan, K., Lewis, M. D., Spurlock, Gillian, Foord, S. M., Scanlon, Maurice Francis, Mir, M. A. and Lewis, Malcolm James 1986. Effect of hypothalamic (Na++K+) atpase inhibitor on isolated rabbit aortic strips. Clinical Science 70 (S13) , 23P-24P. |
Jones, Dylan Marc ORCID: https://orcid.org/0000-0001-8783-5542, Jones, M. E., Lewis, Malcolm John and Spriggs, T. L. 1979. Drugs and human memory: effects of low doses of nitrazepam and hyoscine on retention. British Journal Of Clinical Pharmacology 7 (5) , pp. 479-483. 10.1111/j.1365-2125.1979.tb00989.x |
Jones, Dylan Marc ORCID: https://orcid.org/0000-0001-8783-5542, Lewis, Malcolm John and Spriggs, T. L. 1978. The effects of low doses of diazepam on human performance in group administered tasks. British Journal Of Clinical Pharmacology 6 (4) , pp. 333-337. 10.1111/j.1365-2125.1978.tb00860.x |
Kandiah, D., Penny, W. J., Fraser, Alan Gordon and Lewis, Malcolm John A possible drug interaction between rifampicin and enalapril. European Journal of Clinical Pharmacology 35 (4) , pp. 431-432. 10.1007/bf00561378 |