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Number of items: 41.

Gilbert, Sophie J., Meakin, Lee B., Bonnet, Cleo S., Nowell, Mari A., Ladiges, Warren C., Morton, John, Duance, Victor C. ORCID: https://orcid.org/0000-0002-7555-2016 and Mason, Deborah J. ORCID: https://orcid.org/0000-0002-8666-6094 2014. Deletion of P58IPK, the cellular inhibitor of the protein kinases PKR and PERK, causes bone changes and joint degeneration in mice. Frontiers in Endocrinology 5 , 174. 10.3389/fendo.2014.00174
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Garbers, Christoph, Monhasery, Niloufar, Aparicio-Siegmund, Samadhi, Lokau, Juliane, Baran, Paul, Nowell, Mari Ann, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711, Rose-John, Stefan and Scheller, Jürgen 2014. The interleukin-6 receptor Asp358Ala single nucleotide polymorphism rs2228145 confers increased proteolytic conversion rates by ADAM proteases. Biochimica et Biophysica Acta - Molecular Basis of Disease 1842 (9) , pp. 1485-1494. 10.1016/j.bbadis.2014.05.018
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Greenhill, Claire J., Jones, Gareth Wyn, Nowell, Mari Ann, Newton, Zarabeth, Harvey, Ann K., Moideen, Abdul Nazeer, Collins, Fraser L., Bloom, Anja C., Coll, Rebecca C., Robertson, Avril A. B., Cooper, Matthew A., Rosas, Marcela ORCID: https://orcid.org/0000-0002-9442-9638, Taylor, Philip Russel ORCID: https://orcid.org/0000-0003-0163-1421, O'Neill, Luke A., Humphreys, Ian R. ORCID: https://orcid.org/0000-0002-9512-5337, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2014. Interleukin-10 regulates the inflammasome-driven augmentation of inflammatory arthritis and joint destruction. Arthritis Research and Therapy 16 (4) , 419. 10.1186/s13075-014-0419-y
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Jones, Gareth Wyn, Greenhill, C. J., Williams, J. O., Nowell, Mari Ann, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Jenkins, B. J. and Jones, S. A. 2013. Exacerbated inflammatory arthritis in response to hyperactive gp130 signalling is independent of IL-17A. Annals of the Rheumatic Diseases 72 (10) , pp. 1738-1742. 10.1136/annrheumdis-2013-203771
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Greenhill, Claire J., Jones, Gareth Wyn, Nowell, Mari Ann, Harvey, Ann, Moideen, Abdul Nazeer, Collins, Fraser, Bloom, Anja Constanze, Coll, R., Rosas, Marcela ORCID: https://orcid.org/0000-0002-9442-9638, Taylor, Philip Russel ORCID: https://orcid.org/0000-0003-0163-1421, O'Neill, L. A., Humphreys, Ian R. ORCID: https://orcid.org/0000-0002-9512-5337, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2013. Interleukin 10 control of the inflammasome restricts arthritic bone erosion [Abstract]. Cytokine 63 (3) , p. 267. 10.1016/j.cyto.2013.06.105

Hayes, Anthony Joseph, Reynolds, Scott, Nowell, Mari Ann, Meakin, Lee B., Habicher, Judith, Ledin, Johan, Bashford, Andrew ORCID: https://orcid.org/0000-0003-1628-0898, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Hammond, Chrissy L. 2013. Spinal deformity in aged zebrafish Is accompanied by degenerative changes to their vertebrae that resemble osteoarthritis. PLoS ONE 8 (9) , e75787. 10.1371/journal.pone.0075787
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Moideen, Abdul Nazeer, Evans, Laura, Osgood, Louise Emma, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 and Nowell, Mari Ann 2013. Characterization of enzymes involved in nicotinamide adenine dinucleotide biosynthesis in rheumatoid arthritis synovium and cytokine-stimulated synovial fibroblasts [Abstracts]. Rhuematology 52 (s1) , pp. 138-139.

Chakraborty, Mallinath, McGreal, Eamon Patrick, Davies, Philip Lloyd, Nowell, Mari Ann, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 and Kotecha, Sailesh ORCID: https://orcid.org/0000-0003-3535-7627 2013. Role of interleukin-6, its receptor and soluble gp130 in chronic lung disease of prematurity. Neonatology 104 (3) , pp. 161-167. 10.1159/000351015

Greenhill, Claire J., Jones, Gareth Wyn, Nowell, Mari Ann, Moideen, Abdul Nazeer, Rosas, Marcela ORCID: https://orcid.org/0000-0002-9442-9638, Taylor, Philip Russel ORCID: https://orcid.org/0000-0003-0163-1421, Humphreys, Ian R. ORCID: https://orcid.org/0000-0002-9512-5337, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2012. Cross-talk between IL-10 and the inflammasome regulates bone erosions during rheumatoid arthritis [Abstract]. Immunology 137 , pp. 43-44.

Bonnet, Cleo, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Harvey, Ann, Gilbert, Sophie Jane, Moideen, Abdul Nazeer, Nowell, Mari Ann and Mason, Deborah Jane ORCID: https://orcid.org/0000-0002-8666-6094 2012. Intra-articular AMPA/kainate glutamate receptor antagonists alleviate inflammation, pain and pathology in rat antigen induced arthritis [Abstract]. Osteoporosis International 23 , S527-S527.

Moideen, Abdul Nazeer, Evans, Laura, Osgood, Louise Emma, Williams, Anwen ORCID: https://orcid.org/0000-0001-6118-020X, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 and Nowell, Mari Ann 2012. Nicotinamide adenine dinucleotide (NAD plus) biosynthesis enzymes in rheumatoid arthritis [Abstract]. Rhuematology 51 (s3) , p. 142. 10.1093/rheumatology/kes108

Jones, Gareth Wyn, Greenhill, Claire J., Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Nowell, Mari Ann, Jenkins, Brian J. and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2012. Interleukin-27 receptor-deficient mice develop exacerbated inflammatory arthritis associated with heightened T- and B-cell responses [Abstract]. Rhuematology 51 (s3) , pp. 43-44. 10.1093/rheumatology/kes117

Greenhill, Claire, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Jones, Gareth Wyn, Nowell, Mari Ann, Moideen, Abdul Nazeer, Rosas, Marcela ORCID: https://orcid.org/0000-0002-9442-9638, Taylor, Philip Russel ORCID: https://orcid.org/0000-0003-0163-1421, Humphreys, Ian R. ORCID: https://orcid.org/0000-0002-9512-5337 and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2012. The regulation of arthritic bone erosions by il-10 [Abstract]. Rhuematology 51 , p. 48. 10.1093/rheumatology/kes117

Nowell, Mari Ann, Evans, Laura Catherine and Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X 2012. PBEF/NAMPT/visfatin: a promising drug target for treating rheumatoid arthritis? Future Medicinal Chemistry 4 (6) , pp. 751-769. 10.4155/fmc.12.34

Greenhill, Claire J., Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Jones, Gareth Wyn, Nowell, Mari Ann, Rosas, Marcela ORCID: https://orcid.org/0000-0002-9442-9638, Taylor, Philip Russel ORCID: https://orcid.org/0000-0003-0163-1421, Humphreys, Ian R. ORCID: https://orcid.org/0000-0002-9512-5337 and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2011. The regulation of arthritic bone erosions by IL-10 [Abstract]. Immunology 135 (s1) , p. 158. 10.1111/j.1365-2567.2011.03534.x

Bonnet, C. S., Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Moideen, A. N., Nowell, Mari Ann and Mason, Deborah Jane 2011. Intra-articular AMPA/kainate glutamate receptor antagonists alleviate inflammation, pain and pathology in rat antigen induced arthritis [Abstract]. International Journal of Experimental Pathology 92 (6) , A14-A14. 10.1111/j.1365-2613.2011.00780.x

Jones, Gareth Wyn, Greenhill, C. J., Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Nowell, Mari Ann, Jenkins, B. J. and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2011. Interleukin-27 receptor-deficient mice develop exacerbated inflammatory arthritis associated with heightened T- and B-cell responses [Abstract]. Immunology 135 (S1) , p. 158. 10.1111/j.1365-2567.2011.03534.x

Jones, Gareth Wyn, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Nowell, Mari Ann, Jenkins, Brian J. and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2011. Interleukin-27 receptor-deficient mice develop exacerbated inflammatory arthritis associated with heightened T- and B- cell responses [Abstract]. Arthritis and Rheumatism 63 (s10) , S978-S978. 10.1002/art.33310

Evans, Laura Catherine, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Hayes, Anthony Joseph, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 and Nowell, Mari Ann 2011. Suppression of leukocyte infiltration and cartilage degradation by selective inhibition of pre-B cell colony-enhancing factor/visfatin/nicotinamide phosphoribosyltransferase: Apo866-mediated therapy in human fibroblasts and murine collagen-induced arthritis. Arthritis and Rheumatism 63 (7) , pp. 1866-1877. 10.1002/art.30338

Leggate, Melanie, Nowell, Mari Ann, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 and Nimmo, Myra N. 2010. The response of interleukin-6 and soluble interleukin-6 receptor isoforms following intermittent high intensity and continuous moderate intensity cycling. Cell Stress and Chaperones 15 (6) , pp. 827-833. 10.1007/s12192-010-0192-z

Nowell, Mari Ann, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Carty, Sara Madelaine, Scheller, Jurgen, Hayes, Anthony Joseph, Jones, Gareth Wyn, Richards, Peter James, Slinn, Simon James, Ernst, Matthias, Jenkins, Brendan J., Topley, Nicholas, Rose-John, Stephen and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2009. Therapeutic targeting of IL-6 trans signaling counteracts STAT3 control of experimental inflammatory arthritis. Journal of Immunology 182 (1) , pp. 613-622.

Nowell, Mari Ann and Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X 2008. Selective inhibition of PBEF activity with a small molecule inhibitor, APO866 ameliorates collagen-induced arthritis [Abstract]. Rheumatology 47 , II58-II59.

Jones, Gareth Wyn, Newton, Zarabeth, Nowell, Mari Ann, Jenkins, B. J., Ernst, M., Topley, Nicholas, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2008. TL1A negatively regulates development of T helper 17 cells [Abstract]. Rheumatology 47 (S2) , II20-II20. 10.1093/rheumatology/kem509

Longhi, Maria Paula, Wright, Kate Louise, Lauder, Sarah Nicol, Nowell, Mari Ann, Jones, Gareth Wyn, Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 2008. Interleukin-6 is crucial for recall of influenza-specific memory cd4+ t cells. PLoS Pathogens 4 (2) , e1000006. 10.1371/journal.ppat.1000006
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Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711, Jones, Gareth Wyn, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X and Nowell, Mari Ann 2008. Appreciating the balance between classical interleukin (IL)-6 receptor signaling and IL-6 trans-signaling: implications for arthritis progression. Immunology Endocrine & Metabolic Agents in Medicinal Chemistry 8 (3) , pp. 235-246.

Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Hayes, Anthony Joseph, Tudor, D., Nowell, Mari Ann and Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877 2008. Chondroitin sulphate motifs as biomarkers for the stem/progenitor cell niche in musculoskeletal tissues. European Cells and Materials 16 (Supp 2) , p. 47.

Hayes, Anthony Joseph, Tudor, Debbie, Nowell, Mari Ann, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877 2008. Chondroitin sulfate sulfation motifs as putative biomarkers for isolation of articular cartilage progenitor cells. Journal of Histochemistry & Cytochemistry 56 (2) , pp. 125-38. 10.1369/jhc.7A7320.2007

Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Richards, Peter James, Thomas, Eleri, Carty, Sara Madelaine, Nowell, Mari Ann, Goodfellow, Rhian Mair, Dent, Colin Michael, Williams, Bryan Davies, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 and Topley, Nicholas 2007. Interferon-γ protects against the development of structural damage in experimental arthritis by regulating polymorphonuclear neutrophil influx into diseased joints. Arthritis & Rheumatism 56 (7) , pp. 2244-2254. 10.1002/art.22732

Carty, Sara Madelaine, Nowell, Mari Ann, Lauder, Sarah Nicol, Goodfellow, Rhian Mair, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711, Williams, B. D. and Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X 2007. Combination therapy with etanercept and sgp130 for rheumatoid arthritis is more effective than monotherapy [Abstract]. Rheumatology 46 (s1) , I18-I18. 10.1093/rheumatology/kem1007

Campinho, Marco A., Silva, Nádia, Nowell, Mari Ann, Llewellyn, Lynda, Sweeney, Glen E. and Power, Deborah M. 2007. Troponin T isoform expression is modulated during Atlantic Halibut metamorphosis. BMC Developmental Biology 7 (1) , 71. 10.1186/1471-213X-7-71

Dimitrov, Stoyan, Lange, Tanja, Benedict, Christian, Nowell, Mari Ann, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711, Scheller, Jurgen, Rose-John, Stefan and Born, Jan 2006. Sleep enhances IL-6 trans-signaling in humans. The FASEB Journal 20 (12) , pp. 2174-2176. 10.1096/fj.06-5754fje

Carty, Sara Madelaine, Nowell, Mari Ann, Goodfellow, Rhian Mair, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711, Williams, B. D. and Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X 2006. TINFa and IL-6/slL-6R interactions regulate the magnitude and the phenotype of synovial Leucocyte infiltration in rheumatoid arthritis [Abstract]. Arthritis and Rheumatism 54 (9) , S597-S597.

Nowell, Mari Ann, Richards, Peter James, Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153, Ognjanovic, Simona, Topley, Nicholas, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Bryant-Greenwood, Gillian and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2006. Regulation of pre-B cell colony-enhancing factor by STAT-3-dependent interleukin-6 trans-signaling: implications in the pathogenesis of rheumatoid arthritis. Arthritis & Rheumatism 54 (7) , pp. 2084-2095. 10.1002/art.21942

Peake, N. J., Khawaja, K., Myers, A., Nowell, Mari Ann, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711, Rowan, A. D., Cawston, T. E. and Foster, H. E. 2006. Interleukin-6 signalling in juvenile idiopathic arthritis is limited by proteolytically cleaved soluble interleukin-6 receptor. Rheumatology 45 (12) , pp. 1485-1489. 10.1093/rheumatology/kel154

Richards, Peter James, Nowell, Mari Ann, Horiuchi, Sankichi, McLoughlin, Rachel Mary, Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153, Grau, Sandra, Yamamoto, Naoki, Ehrmann, Michael ORCID: https://orcid.org/0000-0002-1927-260X, Rose-John, Stefan, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Topley, Nicholas and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2006. Functional characterization of a soluble gp130 isoform and its therapeutic capacity in an experimental model of inflammatory arthritis. Arthritis & Rheumatism 54 (5) , pp. 1662-1672. 10.1002/art.21818

Carty, S. M., Nowell, Mari Ann, Goodfellow, Rhian Mair, Topley, Nicholas, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711, Williams, B. D. and Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X 2005. Interleukin 6 (IL-6) signalling in rheumatoid arthritis. Rheumatology 44 , I38-I38.

McLoughlin, Rachel Mary, Hurst, Suzanne Maria, Nowell, Mari Ann, Harris, Dean Anthony, Horiuchi, Sankichi, Morgan, Llinos Wyn, Yamamoto, Naoki, Wilkinson, Thomas S., Topley, Nicholas and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2004. Differential regulation of neutrophil-activating chemokines by IL-6 and its soluble receptor isoforms. The Journal of Immunology 172 , pp. 5676-83.

Nowell, Mari Ann, Richards, Peter James, Horiuchi, Sankichi, Yamamoto, Naoki, Rose-John, Stefan, Topley, Nicholas, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2003. Soluble IL-6 receptor governs IL-6 activity in experimental arthritis: blockade of arthritis severity by soluble glycoprotein 130. The Journal of Immunology 171 (6) , pp. 3202-3209.

Coffey, Marcus Jonathan, Natarajan, Rama, Chumley, Philip H., Coles, Barbara, Thimmalapura, Pushpa-Rekha, Nowell, Mari Ann, Kühn, Hartmut, Lewis, Malcolm John, Freeman, Bruce A. and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2001. Catalytic consumption of nitric oxide by 12/15- lipoxygenase: inhibition of monocyte soluble guanylate cyclase activation. Proceedings of the National Academy of Sciences of the United States of America (PNAS) ISSN 1091-6490 98 (14) , pp. 8006-8011. 10.1073/pnas.141136098

Power, D. M., Llewellyn, L., Faustino, M., Nowell, Mari Ann, Björnsson, B. T., Einarsdottir, I. E, Canario, A.V.M and Sweeney, Glen E. 2001. Thyroid hormones in growth and development of fish. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 130 (4) , pp. 447-459. 10.1016/S1532-0456(01)00271-X

Nowell, Mari Ann, DM, Power, PM, Guerreiro, L, Llewellyn, V, Ramsurn, T, Wigham and Sweeney, Glen E. 2000. Cloning and expression of an elongation factor-1a in sea bream (Sparus aurata) larvae and adult tissue. Marine Biotechnology 2 (2) , pp. 173-179. 10.1007/s101269900022

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