Piret, Gaelle, Fung, Fun Man, Fullerton, Josie, Fico, Giuseppe, Ponkratov, Dmitriy, Chen, Wenxin, Latorre, Daniela, Wan, Kirsty Y., Aghaeepour, Nima, Welgryn, Jules, Razi, Adeel, Silveyra, Patricia, Altun, Ahmet, Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222, Hughes, Alice C. and Wolfram, Joy
2024.
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Schwartz, Uwe, Llamazares Prada, Maria, Pohl, Stephanie T., Richter, Mandy, Tamas, Raluca, Schuler, Michael, Keller, Corinna, Mijosek, Vedrana, Muley, Thomas, Schneider, Marc A., Quast, Karsten, Hey, Joschka, Heubel, Claus P., Warth, Arne, Winter, Hauke, Sercin, Ozdemirhan, Karmouty-Quintana, Harry, Jyothula, Soma S.K., Patel, Manish K., Herth, Felix, Koch, Ina, Petrosino, Giuseppe, Titimeaua, Alexandru, Mardin, Balca R., Weichenhan, Dieter, Jurkowski, Tomasz P. ORCID: https://orcid.org/0000-0002-2012-0240, Imbusch, Charles D., Brors, Benedikt, Benes, Vladimir, Jung, Birgit, Wyatt, David, Stahl, Heiko F., Plass, Christoph and Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222 2023. High-resolution transcriptomic and epigenetic profiling identifies novel regulators of COPD. The EMBO Journal 42 , e111272. 10.15252/embj.2022111272 |
Dordevic, Marija, Stepper, Peter, Feuerstein-Akgoz, Clarissa, Gerhauser, Clarissa, Paunovic, Verica, Tolic, Anja, Rajic, Jovana, Dinic, Svetlana, Uskokovic, Aleksandra, Grdovic, Nevena, Mihailovic, Mirjana, Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222, Jurkowski, Tomasz P. ORCID: https://orcid.org/0000-0002-2012-0240, Jovanovic, Jelena Arambasic and Vidakovic, Melita 2023. EpiCRISPR targeted methylation of Arx gene initiates transient switch of mouse pancreatic alpha to insulin-producing cells. Frontiers in Endocrinology 14 , 1134478. 10.3389/fendo.2023.1134478 |
Pohl, Stephanie T., Prada, Maria Llamazares, Espinet, Elisa and Jurkowska, Renata ORCID: https://orcid.org/0000-0002-4507-2222 2022. Practical considerations for complex tissue dissociation for single-cell transcriptomics. Calogero, R.A. and Benes, V., eds. Single Cell Transcriptomics. Methods in Molecular Biology, Vol. 2584. New York: Springer, pp. 371-387. (10.1007/978-1-0716-2756-3_19) |
Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222 and Jeltsch, Albert 2022. Enzymology of mammalian DNA methyltransferases. Jeltsch, Albert and Jurkowska, Renata Z., eds. DNA Methyltransferases - Role and Function, Vol. 1389. Advances in Experimental Medicine and Biology, Springer, pp. 69-110. (10.1007/978-3-031-11454-0_4) |
Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222 and Jeltsch, Albert 2022. Mechanisms and biological roles of DNA methyltransferases and DNA methylation: From past achievements to future challenges. Jeltsch, Albert and Jurkowska, Renata Z., eds. DNA Methyltransferases - Role and Function, Vol. 1389. Advances in Experimental Medicine and Biology, Springer, pp. 1-19. (10.1007/978-3-031-11454-0_1) |
Ravichandran, Mirunalini, Rafalski, Dominik, Davies, Claudia I., Ortega-Recalde, Oscar, Nan, Xinsheng ORCID: https://orcid.org/0000-0002-0865-7934, Glanfield, Cassandra R., Kotter, Annika, Misztal, Katarzyna, Wang, Andrew H., Wojciechowski, Marek, Razew, Michal, Mayyas, Issam M., Kardailsky, Olga, Schwartz, Uwe, Zembrzycki, Krzysztof, Morison, Ian M., Helm, Mark, Weichenhan, Dieter, Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222, Krueger, Felix, Plass, Christoph, Zacharias, Martin, Bochtler, Matthias, Hore, Timothy A. and Jurkowski, Tomasz P. ORCID: https://orcid.org/0000-0002-2012-0240 2022. Pronounced sequence specificity of the TET enzyme catalytic domain guides its cellular function. Science Advances 8 (36) 10.1126/sciadv.abm2427 |
Prada, Maria Llamazares, Espinet, Elisa, Mijosek, Vedrana, Schwartz, Uwe, Lutsik, Pavlo, Tamas, Raluca, Richter, Mandy, Behrendt, Annika, Pohl, Stephanie T., Benz, Naja P., Muley, Thomas, Warth, Arne, Heusel, Claus Peter, Winter, Hauke, Landry, Jonathan J.M., Herth, Felix J.F., Mertens, Tinne C.J., Karmouty-Quintana, Harry, Koch, Ina, Benes, Vladimir, Korbel, Jan O., Waszak, Sebastian M., Trumpp, Andreas, Wyatt, David M., Stahl, Heiko F., Plass, Christoph and Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222 2021. Versatile workflow for cell-type resolved transcriptional and epigenetic profiles from cryopreserved human lung. JCI Insight 6 (5) , e140443. 10.1172/jci.insight.140443 |
Ogger, Patricia P., Silva, Johnatas Dutra, Aghapour, Mahyar, Persson, Irma Mahmutovic, Tulen, Christy, Jurkowska, Renata ORCID: https://orcid.org/0000-0002-4507-2222 and Ubags, Niki D. 2020. Early Career Members at the ERS Lung Science Conference 2020: metabolic alterations in lung ageing and disease. Breathe 16 (3) , 200063. 10.1183/20734735.0063-2020 |
Gao, Linfeng, Emperle, Max, Guo, Yiran, Grimm, Sara A., Ren, Wendan, Adam, Sabrina, Uryu, Hidetaka, Zhang, Zhi-Min, Chen, Dongliang, Yin, Jiekai, Dukatz, Michael, Anteneh, Hiwot, Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222, Lu, Jiuwei, Wang, Yinsheng, Bashtrykov, Pavel, Wade, Paul A., Wang, Gang Greg, Jeltsch, Albert and Song, Jkui 2020. Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms. Nature Communications 11 , 3355. 10.1038/s41467-020-17109-4 |
Serçin, Özdemirhan, Reither, Sabine, Roidos, Paris, Ballin, Nadja, Palikyras, Spyridon, Baginska, Anna, Rein, Katrin, Llamazares, Maria, Halavatyi, Aliaksandr, Winter, Hauke, Muley, Thomas, Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222, Abdollahi, Amir, Zenke, Frank T., Neumann, Beate and Mardin, Balca R. 2019. A solid-phase transfection platform for arrayed CRISPR screens. Molecular Systems Biology 15 (12) , e8983. 10.15252/msb.20198983 |
Rajavelu, Arumugam, Lungu, Cristiana, Emperle, Max, Dukatz, Michael, Bröhm, Alexander, Broche, Julian, Hanelt, Ines, Parsa, Edris, Schiffers, Sarah, Karnik, Rahul, Meissner, Alexander, Carell, Thomas, Rathert, Philipp, Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222 and Jeltsch, Albert 2018. Chromatin-dependent allosteric regulation of DNMT3A activity by MeCP2. Nucleic Acids Research 46 (17) , 9044–9056. 10.1093/nar/gky715 |
Emperle, Max, Dukatz, Michael, Kunert, Stefan, Holzer, Katharina, Rajavelu, Arumugam, Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222 and Jeltsch, Albert 2018. The DNMT3A R882H mutation does not cause dominant negative effects in purified mixed DNMT3A/R882H complexes. Scientific Reports 8 (1) , -. 10.1038/s41598-018-31635-8 |
Emperle, Max, Rajavelu, Arumugam, Kunert, Stefan, Arimondo, Paola B., Reinhardt, Richard, Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222 and Jeltsch, Albert 2018. The DNMT3A R882H mutant displays altered flanking sequence preferences. Nucleic Acids Research 46 (6) , pp. 3130-3139. 10.1093/nar/gky168 |
Ravichandran, M., Jurkowska, Renata ORCID: https://orcid.org/0000-0002-4507-2222 and Jurkowski, Tomasz ORCID: https://orcid.org/0000-0002-2012-0240 2018. Target specificity of mammalian DNA methylation and demethylation machinery. Organic and Biomolecular Chemistry (9) , pp. 1419-1435. 10.1039/C7OB02574B |
Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222, Qin, Su, Kungulovski, Goran, Tempel, Wolfram, Liu, Yanli, Bashtrykov, Pavel, Stiefelmaier, Judith, Jurkowski, Tomasz P. ORCID: https://orcid.org/0000-0002-2012-0240, Kudithipudi, Srikanth, Weirich, Sara, Tamas, Raluca, Wu, Hong, Dombrovski, Ludmila, Loppnau, Peter, Reinhardt, Richard, Min, Jinrong and Jeltsch, Albert 2017. H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1. Nature Communications 8 , 2057. 10.1038/s41467-017-02259-9 |
Stepper, Peter, Kungulovski, Goran, Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222, Chandra, Tamir, Krueger, Felix, Reinhardt, Richard, Reik, Wolf, Jeltsch, Albert and Jurkowski, Tomasz P. ORCID: https://orcid.org/0000-0002-2012-0240 2017. Efficient targeted DNA methylation with chimeric dCas9-Dnmt3a-Dnmt3L methyltransferase. Nucleic Acids Research 45 (4) , pp. 1703-1713. 10.1093/nar/gkw1112 |
Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222 and Jeltsch, Albert 2016. Enzymology of mammalian DNA methyltransferases. Advances in Experimental Medicine and Biology 945 , pp. 87-122. 10.1007/978-3-319-43624-1_5 |
Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222 and Jeltsch, Albert 2016. Mechanisms and biological roles of DNA methyltransferases and DNA methylation: From past achievements to future challenges. Advances in Experimental Medicine and Biology 945 , pp. 1-17. 10.1007/978-3-319-43624-1_1 |
Jeltsch, Albert and Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222 2016. Allosteric control of mammalian DNA methyltransferases - a new regulatory paradigm. Nucleic Acids Research 44 (18) , pp. 8556-8575. 10.1093/nar/gkw723 |
Lungu, Cristiana, Muegge, Kathrin, Jeltsch, Albert and Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222 2015. An ATPase-deficient variant of the SNF2 family member HELLS shows altered dynamics at pericentromeric Heterochromatin. Journal of Molecular Biology 427 (10) , pp. 1903-1915. 10.1016/j.jmb.2015.03.014 |
Kungulovski, Goran, Kycia, Ina, Tamas, Raluca, Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222, Kudithipudi, Srikanth, Henry, Chisato, Reinhardt, Richard, Labhart, Paul and Jeltsch, Albert 2014. Application of histone modification-specific interaction domains as an alternative to antibodies. Genome Research 24 (11) , pp. 1842-1853. 10.1101/gr.170985.113 |
Emperle, Max, Rajavelu, Arumugam, Reinhardt, Richard, Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222 and Jeltsch, Albert 2014. Cooperative DNA binding and protein/DNA fiber formation increases the activity of the Dnmt3a DNA methyltransferase. Journal of Biological Chemistry 289 (43) , pp. 29602-29613. 10.1074/jbc.M114.572032 |
Jeltsch, Albert and Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222 2014. New concepts in DNA methylation. Trends in Biochemical Sciences 39 (7) , pp. 310-318. 10.1016/j.tibs.2014.05.002 |
Bashtrykov, Pavel, Jankevicius, Gytis, Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222, Ragozin, Sergey and Jeltsch, Albert 2014. The UHRF1 protein stimulates the activity and specificity of the maintenance DNA methyltransferase DNMT1 by an allosteric mechanism. Journal of Biological Chemistry 289 (7) , pp. 4106-4116. 10.1074/jbc.M113.528893 |
Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222 and Jeltsch, Albert 2013. Genomic imprinting-the struggle of the genders at the molecular level. Angewandte Chemie International Edition 52 (51) , pp. 13524-13536. 10.1002/anie.201307005 |
Jeltsch, Albert and Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222 2013. Multimerization of the Dnmt3a DNA methyltransferase and its functional implications. Progress in Molecular Biology and Translational Science 117 , pp. 445-464. 10.1016/B978-0-12-386931-9.00016-7 |
Siddique, Abu Nasar, Nunna, Suneetha, Rajavelu, Arumugam, Zhang, Yingying, Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222, Reinhardt, Richard, Rots, Marianne G., Ragozin, Sergey, Jurkowski, Tomasz P. ORCID: https://orcid.org/0000-0002-2012-0240 and Jeltsch, Albert 2012. Targeted methylation and gene silencing of VEGF-A in human cells by using a designed Dnmt3a-Dnmt3L single-chain fusion protein with increased DNA methylation activity. Journal of Molecular Biology 425 (3) , 479—491. 10.1016/j.jmb.2012.11.038 |
Bashtrykov, Pavel, Jankevicius, Gytis, Smarandache, Anita, Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222, Ragozin, Sergey and Jeltsch, Albert 2012. Specificity of Dnmt1 for methylation of hemimethylated CpG sites resides in its catalytic domain. Chemistry and Biology 19 (5) , pp. 572-578. 10.1016/j.chembiol.2012.03.010 |
Halby, Ludovic, Champion, Christine, Sénamaud-Beaufort, Catherine, Ajjan, Sophie, Drujon, Thierry, Rajavelu, Arumugam, Ceccaldi, Alexandre, Jurkowska, Renata ORCID: https://orcid.org/0000-0002-4507-2222, Lequin, Olivier, Nelson, William G., Guy, Alain, Jeltsch, Albert, Guianvarc'h, Dominique, Ferroud, Clotilde and Arimondo, Paola B. 2012. Rapid synthesis of new DNMT inhibitors derivatives of procainamide. ChemBioChem 13 (1) , pp. 157-165. 10.1002/cbic.201100522 |
Jurkowska, Renata Zofia ORCID: https://orcid.org/0000-0002-4507-2222, Jurkowski, Tomasz Piotr ORCID: https://orcid.org/0000-0002-2012-0240 and Jeltsch, Albert 2011. Structure and function of mammalian DNA methyltransferases. ChemBioChem 12 (2) , 206—222. 10.1002/cbic.201000195 |
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Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222, Siddique, Abu Nasar, Jurkowski, Tomasz P. ORCID: https://orcid.org/0000-0002-2012-0240 and Jeltsch, Albert 2011. Approaches to enzyme and substrate design of the murine Dnmt3a DNA methyltransferase. ChemBioChem 12 (10) , 1589—1594. 10.1002/cbic.201000673 |
Ceccaldi, Alexandre, Rajavelu, Arumugam, Champion, Christine, Rampon, Christine, Jurkowska, Renata ORCID: https://orcid.org/0000-0002-4507-2222, Jankevicius, Gytis, Sénamaud-Beaufort, Catherine, Ponger, Loïc, Gagey, Nathalie, Dali Ali, Hana, Tost, Jörg, Vriz, Sophie, Ros, Sindu, Dauzonne, Daniel, Jeltsch, Albert, Guianvarc'h, Dominique and Arimondo, Paola B. 2011. C5-DNA methyltransferase inhibitors: from screening to effects on zebrafish embryo development. ChemBioChem 12 (9) , pp. 1337-1345. 10.1002/cbic.201100130 |
Siddique, Abu Nasar, Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222, Jurkowski, Tomasz P. ORCID: https://orcid.org/0000-0002-2012-0240 and Jeltsch, Albert 2011. Auto-methylation of the mouse DNA-(cytosine C5)-methyltransferase Dnmt3a at its active site cysteine residue. FEBS Journal 278 (12) , 2055—2063. 10.1111/j.1742-4658.2011.08121.x |
Rajavelu, Arumugam, Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222, Fritz, Jürgen and Jeltsch, Albert 2011. Function and disruption of DNA Methyltransferase 3a cooperative DNA binding and nucleoprotein filament formation. Nucleic Acids Research 40 (2) , 569–580. 10.1093/nar/gkr753 |
Champion, Christine, Guianvarc'h, Dominique, Sénamaud-Beaufort, Catherine, Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222, Jeltsch, Albert, Ponger, Loïc, Arimondo, Paola B. and Guieysse-Peugeot, Anne-Laure 2010. Mechanistic insights on the inhibition of C5 DNA methyltransferases by zebularine. PLoS ONE 5 (8) , e12388. 10.1371/journal.pone.0012388 |
Dhayalan, Arunkumar, Rajavelu, Arumugam, Rathert, Philipp, Tamas, Raluca, Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222, Ragozin, Sergey and Jeltsch, Albert 2010. The Dnmt3a PWWP domain reads histone 3 lysine 36 trimethylation and Guides DNA methylation. Journal of Biological Chemistry 285 (34) , pp. 26114-26120. 10.1074/jbc.M109.089433 |
Zhang, Yingying, Jurkowska, Renata ORCID: https://orcid.org/0000-0002-4507-2222, Soeroes, Szabolcs, Rajavelu, Arumugam, Dhayalan, Arunkumar, Bock, Ina, Rathert, Philipp, Brandt, Ole, Reinhardt, Richard, Fischle, Wolfgang and Jeltsch, Albert 2010. Chromatin methylation activity of Dnmt3a and Dnmt3a/3L is guided by interaction of the ADD domain with the histone H3 tail. Nucleic Acids Research 38 (13) , 4246–4253. 10.1093/nar/gkq147 |
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Jeltsch, Albert and Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222 2010. DNA methylation. The Chemical Biology of Nucleic Acids, Wiley, pp. 307-301. (10.1002/9780470664001.ch14) |
Métivier, Raphaël, Gallais, Rozenn, Tiffoche, Christophe, Le Péron, Christine, Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222, Carmouche, Richard P., Ibberson, David, Barath, Peter, Demay, Florence, Reid, George, Benes, Vladimir, Jeltsch, Albert, Gannon, Frank and Salbert, Gilles 2010. Erratum: Cyclical DNA methylation of a transcriptionally active promoter. Nature 463 (7279) , 384. 10.1038/nature08661 |
Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222, Anspach, Nils, Urbanke, Claus, Jia, Da, Reinhardt, Richard, Nellen, Wolfgang, Cheng, Xiaodong and Jeltsch, Albert 2008. Formation of nucleoprotein filaments by mammalian DNA methyltransferase Dnmt3a in complex with regulator Dnmt3L. Nucleic Acids Research 36 (21) , 6656–6663. 10.1093/nar/gkn747 |
Rathert, Philipp, Dhayalan, Arunkumar, Murakami, Marie, Zhang, Xing, Tamas, Raluca, Jurkowska, Renata ORCID: https://orcid.org/0000-0002-4507-2222, Komatsu, Yasuhiko, Shinkai, Yoichi, Cheng, Xiaodong and Jeltsch, Albert 2008. Protein lysine methyltransferase G9a acts on non-histone targets. Nature Chemical Biology 4 (6) , 344–346. 10.1038/nchembio.88 |
Métivier, Raphaël, Gallais, Rozenn, Tiffoche, Christophe, Le Péron, Christine, Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222, Carmouche, Richard P., Ibberson, David, Barath, Peter, Demay, Florence, Reid, George, Benes, Vladimir, Jeltsch, Albert, Gannon, Frank and Salbert, Gilles 2008. Cyclical DNA methylation of a transcriptionally active promoter. Nature 452 (7183) , 45–50. 10.1038/nature06544 |
Jia, Da, Jurkowska, Renata Z. ORCID: https://orcid.org/0000-0002-4507-2222, Zhang, Xing, Jeltsch, Albert and Cheng, Xiaodong 2007. Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation. Nature 449 (7159) , 248–251. 10.1038/nature06146 |
Gallais, Rozenn, Demay, Florence, Barath, Peter, Finot, Laurence, Jurkowska, Renata ORCID: https://orcid.org/0000-0002-4507-2222, Le Guével, Rémy, Gay, Frédérique, Jeltsch, Albert, Métivier, Raphaël and Salbert, Gilles 2007. Deoxyribonucleic acid methyl transferases 3a and 3b associate with the nuclear orphan receptor COUP-TFI during gene activation. Molecular Endocrinology -Baltimore- 21 (9) , 2085–2098. 10.1210/me.2006-0490 |
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