Browse by Current Cardiff authors

Ranieri, Marianna, Schepelmann, Martin, Valenti, Giovanna, Kallay, Enikö and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2023. Editorial: The calcium-sensing receptor: from physiology to pharmacology. Frontiers in Physiology 14 , 1225074. 10.3389/fphys.2023.1225074

Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163, Ward, Jeremy P.T., Yarova, Polina L., Janssen, Luke J., Lee, Tak Hong, Ying, Sun and Corrigan, Chris J. 2022. Topical therapy with negative allosteric modulators of the calcium-sensing receptor (calcilytics) for the management of asthma: the beginning of a new era? European Respiratory Journal 60 (2) , 2102103. 10.1183/13993003.02103-2021

Schepelmann, Martin ORCID: https://orcid.org/0000-0002-7017-5426, Ranieri, Marianna, Lopez-Fernandez, Irene, Webberley, Thomas S., Brennan, Sarah C. ORCID: https://orcid.org/0000-0002-8719-4367, Yarova, Polina L., Graca, Joao, Hanif, Umar-Khetaab, Müller, Christian, Manhardt, Teresa, Salzmann, Martina, Quasnichka, Helen, Price, Sally A., Ward, Donald T., Gilbert, Thierry, Matchkov, Vladimir V., Fenton, Robert A., Herberger, Amanda, Hwong, Jenna, Santa Maria, Christian, Tu, Chia-Ling, Kallay, Enikö, Valenti, Giovanna, Chang, Wenhan and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2022. Impaired mineral ion metabolism in a mouse model of targeted calcium-sensing receptor (CaSR) deletion from vascular smooth muscle cells. Journal of the American Society of Nephrology 33 (7) , pp. 1323-1340. 10.1681/ASN.2021040585

Schepelmann, Martin, Kupper, Nadja, Sladczyk, Marta, Mansfield, Bethan, Manhardt, Teresa, Piatek, Karina, Iamartino, Luca, Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163, Kariuki, Benson M. ORCID: https://orcid.org/0000-0002-8658-3897, Bassetto, Marcella and Kallay, Enikö 2021. Stereo-specific modulation of the extracellular calcium-sensing receptor in colon cancer cells. International Journal of Molecular Sciences 22 (18) , 10124. 10.3390/ijms221810124

Yarova, Polina L., Huang, Ping, Schepelmann, Martin W. ORCID: https://orcid.org/0000-0002-7017-5426, Bruce, Richard, Ecker, Rupert, Nica, Robert, Telezhkin, Vsevolod S. ORCID: https://orcid.org/0000-0002-5054-8774, Traini, Daniela, Gomes dos Reis, Larissa, Kidd, Emma J. ORCID: https://orcid.org/0000-0001-5507-1170, Ford, William R. ORCID: https://orcid.org/0000-0002-8792-6169, Broadley, Kenneth J., Kariuki, Benson M., Corrigan, Christopher J., Ward, Jeremy P. T., Kemp, Paul J. and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2021. Characterisation of negative allosteric modulators of the calcium-sensing receptor, CaSR, for repurposing as a treatment for asthma. Journal of Pharmacology and Experimental Therapeutics 376 (1) , pp. 51-63. 10.1124/jpet.120.000281

Leach, Katie, Hannan, Fadil M., Josephs, Tracy M., Keller, Andrew N., Møller, Thor C., Ward, Donald T., Kallay, Enikö, Mason, Rebecca S., Thakker, Rajesh V., Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163, Conigrave, Arthur D., Bräuner-Osborne, Hans and Ohlstein, Eliot H. 2020. International union of basic and clinical pharmacology. CVIII. Calcium-sensing receptor nomenclature, pharmacology, and function. Pharmacological Reviews 72 (3) , pp. 558-604. 10.1124/pr.119.018531

Scott Roberts, Mary, Gafni, Rachel I, Brillante, Beth, Guthrie, Lori C, Streit, Jamie, Gash, David, Gelb, Jeff, Krusinska, Eva, Brennan, Sarah C ORCID: https://orcid.org/0000-0002-8719-4367, Schepelmann, Martin ORCID: https://orcid.org/0000-0002-7017-5426, Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163, Ezuan Bin Khayat, Mohd, Ward, Donald T, Nemeth, Edward F, Rosskamp, Ralf and Collins, Michael T 2019. Treatment of autosomal dominant hypocalcemia Type 1 with the calcilytic NPSP795 (SHP635). Journal of Bone and Mineral Research 34 (9) , pp. 1609-1618. 10.1002/jbmr.3747

Bazua-Valenti, Silvana, Rojas-Vega, Lorena, Castaneda-Bueno, Maria, Barrera-Chimal, Jonatan, Bautista, Rocio, Cervantes-Perez, Luz G., Vazquez, Norma, Plata, Consuelo, Murillo-de-Ozores, Adrian R., Gonzalez-Mariscal, Lorenza, Ellison, David H., Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163, Bobadilla, Norma A. and Gamba, Gerardo 2018. The calcium-sensing receptor increases activity of the renal NCC through the WNK4-SPAK pathway. Journal of the American Society of Nephrology 29 (7) , pp. 1838-1848. 10.1681/ASN.2017111155

Musante, Ilaria, Mattinzoli, Deborah, Otescu, Lavinia Alexandra, Bossi, Simone, Ikehata, Masami, Gentili, Chiara, Cangemi, Giuliana, Gatti, Cinzia, Emionite, Laura, Messa, Piergiorgio, Ravazzolo, Roberto, Rastaldi, Maria Pia, Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Puliti, Aldamaria 2017. Phenotypic characterization of Grm1crv4 mice reveals a functional role for the type 1 metabotropic glutamate receptor in bone mineralization. Bone 94 , pp. 114-123. 10.1016/j.bone.2016.10.025

Mattinzoli, D., Rastaldi, M.P., Ikehata, M., Armelloni, S., Pignatari, C., Giardino, L.A., Li, M., Alfieri, C.M., Regalia, A., Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Messa, P. 2016. Corrigendum to FGF23-regulated production of fetuin-A (AHSG) in osteocytes [Bone 83 (2016) 35-47]. Bone 93 , p. 236. 10.1016/j.bone.2016.03.008

Kemp, Paul J ORCID: https://orcid.org/0000-0003-2773-973X, Rushton, David J., Yarova, Polina, Schnell, Christian, Geater, Charlene, Hancock, Jane M., Wieland, Annalena, Hughes, Alis, Badder, Luned, Cope, Emma Louise, Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163, Randall, Andrew, Brown, Jonathan T., Allen, Nicholas Denby ORCID: https://orcid.org/0000-0003-4009-186X and Telezhkin, Vsevolod ORCID: https://orcid.org/0000-0002-5054-8774 2016. Improving and accelerating the differentiation and functional maturation of human stem cell-derived neurons: role of extracellular calcium and GABA. The Journal of Physiology 594 (22) , pp. 6583-6594. 10.1113/JP270655

Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Valenti, Giovanna 2016. Localization and function of the renal calcium-sensing receptor. Nature Reviews Nephrology 12 (7) , pp. 414-425. 10.1038/nrneph.2016.59

Yarova, P. L., Davies, C., Price, S.A., Huang, Q., Graca, J. A ., Maleki-Toyserkani, S. ORCID: https://orcid.org/0000-0002-9829-2851, Lowe, A. P. P., Kidd, E. J. ORCID: https://orcid.org/0000-0001-5507-1170, Ford, W.R. ORCID: https://orcid.org/0000-0002-8792-6169, Broadley, K. J. ORCID: https://orcid.org/0000-0002-3339-2050, Ward, J. P. T., Corrigan, J. C., Prakash, Y. S., Kemp, P. J. ORCID: https://orcid.org/0000-0003-2773-973X and Riccardi, D. ORCID: https://orcid.org/0000-0002-7322-3163 2016. Inhaled calcilytics: effects on airway inflammation and remodeling. Respiratory Drug Delivery 1 , pp. 1-12.

Graca, Joao, Schepelmann, Martin ORCID: https://orcid.org/0000-0002-7017-5426, Brennan, Sarah C., Reens, Jaimini, Chang, Wenhan, Yan, Paul, Toka, Hakan, Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Price, Sally A. 2016. Comparative expression of the extracellular calcium sensing receptor in rat, mouse and human kidney. American Journal of Physiology-Renal Physiology 310 (6) , F518-F533. 10.1152/ajprenal.00208.2015

Brennan, Sarah C. ORCID: https://orcid.org/0000-0002-8719-4367, Wilkinson, William J., Tseng, Hsiu-Er, Finney, Brenda, Monk, Bethan, Dibble, Holly, Quilliam, Samantha, Warburton, David, Galietta, Luis J., Kemp, Paul J. ORCID: https://orcid.org/0000-0003-2773-973X and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2016. The extracellular calcium-sensing receptor regulates human fetal lung development via CFTR. Scientific Reports 6 , 21975. 10.1038/srep21975

Schepelmann, M. ORCID: https://orcid.org/0000-0002-7017-5426, Yarova, P. L., Lopez-Fernandez, I., Davies, T. S., Brennan, S. C. ORCID: https://orcid.org/0000-0002-8719-4367, Edwards, P. J., Aggarwal, A., Graca, J., Rietdorf, K., Matchkov, V., Fenton, R. A., Chang, W., Krssak, M., Stewart, A., Broadley, K. J. ORCID: https://orcid.org/0000-0002-3339-2050, Ward, D. T., Price, S. A., Edwards, D. H., Kemp, P. J. ORCID: https://orcid.org/0000-0003-2773-973X and Riccardi, D. ORCID: https://orcid.org/0000-0002-7322-3163 2016. The vascular Ca2+-sensing receptor regulates blood vessel tone and blood pressure. American Journal of Physiology - Cell Physiology 310 (3) , C193-C204. 10.1152/ajpcell.00248.2015

Mattinzoli, D., Rastaldi, M.P., Ikehata, M., Armelloni, S., Pignatari, C., Giardino, L.A., Li, M., Alfieri, C.M., Regalia, A., Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Messa, P. 2016. FGF23-regulated production of Fetuin-A (AHSG) in osteocytes. Bone 83 , pp. 35-47. 10.1016/j.bone.2015.10.008

Lopez-Fernandez, Irene, Schepelmann, Martin ORCID: https://orcid.org/0000-0002-7017-5426, Brennan, Sarah C. ORCID: https://orcid.org/0000-0002-8719-4367, Yarova, Polina L. and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2015. The calcium-sensing receptor: one of a kind. Experimental Physiology 100 (12) , pp. 1392-1399. 10.1113/EP085137

Yarova, Polina L., Stewart, Alecia L., Sathish, Venkatachalem, Britt, Rodney D. Jnr., Thompson, Michael A., Lowe, Alexander P. P., Freeman, Michelle, Aravamadun, Bharathi, Kita, Hitohito, Brennan, Sarah C. ORCID: https://orcid.org/0000-0002-8719-4367, Schepelmann, Martin ORCID: https://orcid.org/0000-0002-7017-5426, Davies, Thomas, Yung, Sun, Cholisoh, Zakky, Kidd, Emma J. ORCID: https://orcid.org/0000-0001-5507-1170, Ford, William R. ORCID: https://orcid.org/0000-0002-8792-6169, Broadley, Kenneth J. ORCID: https://orcid.org/0000-0002-3339-2050, Rietdorf, Katja, Chang, Wenham, Bin Khayat, Mohamed E., Ward, Donald T., Corrigan, Christopher J., Ward, Jeremy P. T., Kemp, Paul J. ORCID: https://orcid.org/0000-0003-2773-973X, Pabelick, Christina M., Prakash, Y. S. and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2015. Calcium-sensing receptor antagonists abrogate airways hyperresponsiveness and inflammation in allergic asthma. Science Translational Medicine 7 (284) , 284ra60. 10.1126/scitranslmed.aaa0282

Vazquez, Marisol, Evans, Bronwen A. J. ORCID: https://orcid.org/0000-0003-3664-2569, Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163, Evans, Sam L. ORCID: https://orcid.org/0000-0003-3664-2569, Ralphs, Jim R. ORCID: https://orcid.org/0000-0002-5367-0732, Dillingham, Christopher Mark and Mason, Deborah J. ORCID: https://orcid.org/0000-0002-8666-6094 2014. A new method to investigate how mechanical loading of osteocytes controls osteoblasts. Frontiers in Endocrinology 5 , 208. 10.3389/fendo.2014.00208

Brennan, Sarah C. ORCID: https://orcid.org/0000-0002-8719-4367, Davies, Thomas S., Schepelmann, Martin ORCID: https://orcid.org/0000-0002-7017-5426 and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2014. Emerging roles of the extracellular calcium-sensing receptor in nutrient sensing: control of taste modulation and intestinal hormone secretion. British Journal of Nutrition 111 (S1) , S16-S22. 10.1017/S0007114513002250

Vazquez, Marisol, Evans, B., Evans, S., Ralphs, James ORCID: https://orcid.org/0000-0002-5367-0732, Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Mason, Deborah ORCID: https://orcid.org/0000-0002-8666-6094 2014. Development of a novel in vitro 3D osteoblast-osteocyte co-culture model to investigate mechanically-induced signalling. International Journal of Experimental Pathology 95 (3) , A34-A35. 10.1111/iep.12078

Wadey, Rebecca, Pinches, M. G., Jones, H. B., Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Price, S. A. 2014. Tissue expression and correlation of a panel of urinary biomarkers following Cisplatin-induced kidney injury. Toxicologic Pathology 42 (3) , pp. 591-602. 10.1177/0192623313492044

Varma, Saaket, Mahavadi, Poornima, Sasikumar, Satish, Cushing, Leah, Hyland, Tessa, Rosser, Anne Elizabeth ORCID: https://orcid.org/0000-0002-4716-4753, Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163, Lu, Jining, Kalin, Tanya V., Kalinichenko, Vladimir V., Guenther, Andreas, Ramirez, Maria Isabel, Pardo, Annie, Selman, Moises and Warburton, David 2014. Grainyheadlike 2 distribution reveals novel pathophysiological differences between human idiopathic pulmonary fibrosis and mouse models of pulmonary fibrosis. AJP: Lung Cellular and Molecular Physiology 306 (5) , L405-L419. 10.1152/ajplung.00143.2013

Lembrechts, Robrecht, Brouns, Inge, Schnorbusch, Kathy, Pintelon, Isabel, Kemp, Paul J. ORCID: https://orcid.org/0000-0003-2773-973X, Timmermans, Jean-Pierre, Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Adriaensen, Dirk 2013. Functional expression of the multimodal extracellular calcium-sensing receptor in pulmonary neuroendocrine cells. Journal of Cell Science 126 (19) , pp. 4490-4501. 10.1242/jcs.131656

Ward, D. T., Mughal, M. Z., Ranieri, M., Dvorak-Ewell, M. M., Valenti, G. and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2013. Molecular and clinical analysis of a neonatal severe hyperparathyroidism case caused by a stop mutation in the calcium-sensing receptor extracellular domain representing in effect a human 'knockout'. European Journal of Endocrinology 169 (1) , K1-K7. 10.1530/EJE-13-0094

Brennan, Sarah C. ORCID: https://orcid.org/0000-0002-8719-4367, Thiem, Ursula, Roth, Susanne, Aggarwal, Abhishek, Fetahu, Irfete Sh., Tennakoon, Samawansha, Gomes, Ana Rita, Brandi, Maria Luisa, Bruggeman, Frank, Mentaverri, Romuald, Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Kallay, Enikö 2013. Calcium sensing receptor signalling in physiology and cancer. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1833 (7) , pp. 1732-1744. 10.1016/j.bbamcr.2012.12.011

Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163, Brennan, Sarah C. ORCID: https://orcid.org/0000-0002-8719-4367 and Chang, Wenhan 2013. The extracellular calcium-sensing receptor, CaSR, in fetal development. Best Practice & Research Clinical Endocrinology & Metabolism 27 (3) , pp. 443-453. 10.1016/j.beem.2013.02.010

Brennan, Sarah C. ORCID: https://orcid.org/0000-0002-8719-4367, Finney, Brenda, Lazarou, Maria, Rosser, Anne Elizabeth ORCID: https://orcid.org/0000-0002-4716-4753, Scherf, Caroline, Adriaensen, Dirk, Kemp, Paul J. ORCID: https://orcid.org/0000-0003-2773-973X and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2013. Fetal calcium regulates branching morphogenesis in the developing human and mouse lung: involvement of voltage-gated calcium channels. PLoS ONE 8 (11) , e80294. 10.1371/journal.pone.0080294

Brown, Edward M., Hebert, Steven C., Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Geibel, John P. 2013. The calcium-sensing receptor. Alpern, Robert J., Moe, Orson W. and Caplan, Michael, eds. Seldin and Giebisch's The Kidney (Fifth Edition), Vol. 5. Physiology & Pathophysiology, vol. 1-2. Dordrecht: Elsevier, pp. 2187-2224. (10.1016/B978-0-12-381462-3.00063-X)

Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2012. Parathyroid hormone-independent role for the calcium-sensing receptor in the control of urinary calcium excretion. Journal of the American Society of Nephrology 23 (11) , pp. 1766-1768. 10.1681/ASN.2012090955

Chia, Poh Wai, Brennan, Sarah C. ORCID: https://orcid.org/0000-0002-8719-4367, Slawin, Alexandra M. Z., Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and O'Hagan, David 2012. Allosteric agonists of the calcium receptor (CaR): fluorine and SF5 analogues of cinacalcet. Organic & Biomolecular Chemistry 10 (39) , pp. 7922-7927. 10.1039/c2ob26402a

Ward, Donald T. and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2012. New concepts in calcium-sensing receptor pharmacology and signalling. British Journal of Pharmacology 165 (1) , pp. 35-48. 10.1111/j.1476-5381.2011.01511.x

Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Kemp, Paul J. ORCID: https://orcid.org/0000-0003-2773-973X 2012. The calcium-sensing receptor beyond extracellular calcium homeostasis: Conception, development, adult physiology, and disease. Annual Review of Physiology 74 , pp. 271-297. 10.1146/annurev-physiol-020911-153318

Vazquez, Marisol, Evans, Bronwen Alice James ORCID: https://orcid.org/0000-0002-3082-1008, Ralphs, James Robert ORCID: https://orcid.org/0000-0002-5367-0732, Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Mason, Deborah Jane ORCID: https://orcid.org/0000-0002-8666-6094 2011. Bone in vitro 3D osteoblast-osteocyte co-culture model. International Journal of Experimental Pathology 92 (6) , A18-A18. 10.1111/j.1365-2613.2011.00780.x

Telezhkin, Vsevolod, Brazier, Stephen P., Mears, Ruth, Müller, Carsten T. ORCID: https://orcid.org/0000-0003-0455-7132, Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Kemp, Paul J. ORCID: https://orcid.org/0000-0003-2773-973X 2011. Cysteine residue 911 in C-terminal tail of human BKCaα channel subunit is crucial for its activation by carbon monoxide. Pflugers Archiv-European Journal of Physiology 461 (6) , pp. 665-675. 10.1007/s00424-011-0924-7

Finney, Brenda, Wilkinson, William James, Searchfield, Lydia ORCID: https://orcid.org/0000-0001-9640-9326, Cole, Martin, Bailey, Stacey Louise, Kemp, Paul J. ORCID: https://orcid.org/0000-0003-2773-973X and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2011. An exon 5-less splice variant of the extracellular calcium-sensing receptor rescues absence of the full-length receptor in the developing mouse lung. Experimental Lung Research 37 (5) , pp. 269-278. 10.3109/01902148.2010.545471

Cayzac, S. H., Rocher, A., Obeso, A., Gonzalez, C., Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Kemp, Paul J. ORCID: https://orcid.org/0000-0003-2773-973X 2011. Spermine attenuates carotid body glomus cell oxygen sensing by inhibiting L-type Ca2+ channels. Respiratory Physiology & Neurobiology 175 (1) , pp. 80-89. 10.1016/j.resp.2010.09.009

Wilkinson, William James, Benjamin, Audra, Proost, Ian, Orogo-Wenn, Maria, Yamazaki, Yasuo, Staub, Olivier, Morita, Takashi, Adriaensen, Dirk, Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163, Walters, Dafydd and Kemp, Paul J. ORCID: https://orcid.org/0000-0003-2773-973X 2011. Alveolar epithelial CNGA1 channels mediate cGMP-stimulated, amiloride-insensitive, lung liquid absorption. Pflügers Archiv European Journal of Physiology 462 (2) , pp. 267-279. 10.1007/s00424-011-0971-0

Searchfield, Lydia ORCID: https://orcid.org/0000-0001-9640-9326, Price, Sally, Betton, Graham, Jasani, Bharat, Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Griffiths, David Francis Rees 2011. Glutathione S-transferases as molecular markers of tumour progression and prognosis in renal cell carcinoma. Histopathology 58 (2) , pp. 180-190. 10.1111/j.1365-2559.2010.03733.x

Sourial, S., Searchfield, L., Schuppe-Koistinen, I., Betton, G. R., Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Price, S. A. 2010. Application of Dolichos biflorus in immunoassay detection of kidney collecting duct biomarkers. Biomarkers 15 (5) , pp. 424-435. 10.3109/1354750X.2010.483526

Price, S. A., Davies, D., Rowlinson, R., Copley, C. G., Roche, A., Falkenberg, F. W., Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Betton, G. R. 2010. Characterization of Renal Papillary Antigen 1 (RPA-1), a Biomarker of Renal Papillary Necrosis. Toxicologic Pathology 38 (3) , pp. 346-358. 10.1177/0192623310362246

Telezhkin, V., Brazier, S. P., Cayzac, S. H., Wilkinson, William James, Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Kemp, Paul J ORCID: https://orcid.org/0000-0003-2773-973X 2010. Mechanism of inhibition by hydrogen sulfide of native and recombinant BKCa channels. Respiratory Physiology & Neurobiology 172 (3) , pp. 169-178. 10.1016/j.resp.2010.05.016

Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Brown, E. M. 2010. Physiology and pathophysiology of the calcium-sensing receptor in the kidney. American Journal of Physiology-Renal Physiology 298 (3) , F485-F499. 10.1152/ajprenal.00608.2009.

Warburton, David, El-Hashash, Ahmed, Carraro, Gianni, Tiozzo, Caterina, Sala, Frederic, Rogers, Orquidea, Langhe, Stijn De, Kemp, Paul J. ORCID: https://orcid.org/0000-0003-2773-973X, Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Torday, John 2010. Lung organogenesis. Current Topics in Developmental Biology 90 , pp. 73-158. 10.1016/S0070-2153(10)90003-3

Wilkinson, William James, Gadeberg, H.C., Harrison, A. W. J., Allen, Nicholas Denby ORCID: https://orcid.org/0000-0003-4009-186X, Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Kemp, Paul J ORCID: https://orcid.org/0000-0003-2773-973X 2009. Carbon monoxide is a rapid modulator of recombinant and native P2X(2) ligand-gated ion channels. British Journal of Pharmacology 158 (3) , pp. 862-871. 10.1111/j.1476-5381.2009.00354.x

Kemp, Paul J. ORCID: https://orcid.org/0000-0003-2773-973X, Telezhkin, Vsevolod ORCID: https://orcid.org/0000-0002-5054-8774, Wilkinson, William James, Mears, Ruth, Hanmer, Stuart, Gadeberg, Hanne C., Müller, Carsten T., Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Brazier, Stephen Paul 2009. Enzyme-linked oxygen sensing by potassium channels. Annals of the New York Academy of Sciences 1177 , pp. 112-118. 10.1111/j.1749-6632.2009.05025.x

Topala, Catalin, Schoeber, Joost, Searchfield, Lydia ORCID: https://orcid.org/0000-0001-9640-9326, Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163, Hoenderop, Joost and Bindels, René 2009. Activation of the Ca2+-sensing receptor stimulates the activity of the epithelial Ca2+ channel TRPV5. Cell Calcium 45 (4) , pp. 331-339. 10.1016/j.ceca.2008.12.003

Brazier, Stephen P., Telezhkin, Vsevolod ORCID: https://orcid.org/0000-0002-5054-8774, Mears, Ruth, Müller, T., Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Kemp, Paul J. ORCID: https://orcid.org/0000-0003-2773-973X 2009. Cysteine residues in the C-terminal tail of the human BKCaα subunit are important for channel sensitivity to carbon monoxide. Presented at: International Society of Arterial Chemoreception. 17th Meeting, Valladolid, Spain, 1-5 July 2008. Arterial Chemoreceptors. Advances in Experimental Medicine and Biology (648) Netherlands: Springer Netherlands, pp. 49-56. 10.1007/978-90-481-2259-2_5

Alam, Masih-Ul, Kirton, John Paul, Wilkinson, Fiona L., Towers, Emily, Sinha, Smeeta, Rouhi, Mansour, Vizard, Thomas Neill, Sage, Andrew P., Martin, David, Ward, Donald T., Alexander, Marie Yvonne, Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Canfield, Ann E. 2009. Calcification is associated with loss of functional calcium-sensing receptor in vascular smooth muscle cells. Cardiovascular Research 81 (2) , pp. 260-268. 10.1093/cvr/cvn279

Topala, C.N., Schoeber, J. P. H., Searchfield, Lydia ORCID: https://orcid.org/0000-0001-9640-9326, Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163, Hoenderop, J. G. J. and Bindels, R. J. M. 2009. Activation of the Ca2+-sensing receptor stimulates the activity of the epithelial Ca2+ channel TRPV5. Cell Calcium 45 (4) , pp. 331-339.

Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163, Finney, B. A., Wilkinson, Willam James and Kemp, Paul J ORCID: https://orcid.org/0000-0003-2773-973X 2009. Novel regulatory aspects of the extracellular Ca2+-sensing receptor, CaR. Pflugers Archiv-European Journal of Physiology 458 (6) , pp. 1007-1022. 10.1007/s00424-009-0681-z

De Proost, I., Pintelon, I., Wilkinson, William James, Goethals, S., Brouns, I., Van Nassauw, L., Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163, Timmermans, J. P., Kemp, Paul J ORCID: https://orcid.org/0000-0003-2773-973X and Adriaensen, D. 2009. Purinergic signaling in the pulmonary neuroepithelial body microenvironment unraveled by live cell imaging. The FASEB Journal 23 (4) , pp. 1153-1160. 10.1096/fj.08-109579

Telezhin, V., Brazier, Stephen Paul, Cayzac, S., Müller, Carsten Theodor, Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Kemp, Paul J. ORCID: https://orcid.org/0000-0003-2773-973X 2009. Hydrogen Sulfide inhibits human BKCa channels. Advances in Experimental Medicine and Biology 648 , pp. 65-72. 10.1007/978-90-481-2259-2_7

Cayzac, S., Rocher, A., Obeso, A., Gonzalez, C., Kemp, Paul J. ORCID: https://orcid.org/0000-0003-2773-973X and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2009. Effects of the polyamine spermine on arterial chemoreception. Presented at: International Society of Arterial Chemoreception. 17th Meeting, Valladolid, Spain, 1-5 July 2008. Published in: Gonzalez, Constancio, Nurse, Colin A. and Peers, Chris eds. Arterial chemoreceptors. Advances in Experimental Medicine and Biology (648) Netherlands: Springer Netherlands, pp. 97-104. 10.1007/978-90-481-2259-2_11

Finney, Brenda, Del Moral, Pierre M., Wilkinson, William James, Cayzac, Sebastien, Cole, Martin, Warburton, David, Kemp, Paul J. ORCID: https://orcid.org/0000-0003-2773-973X and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2008. Regulation of mouse lung development by the extracellular calcium-sensing receptor, CaR. Journal of Physiology 586 (24) , pp. 6007-6019. 10.1113/jphysiol.2008.161687

De Proost, Ian, Pintelon, Isabel, Brouns, Inge, Kroese, Alfons B. A., Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163, Kemp, Paul J ORCID: https://orcid.org/0000-0003-2773-973X, Timmermans, Jean-Pierre and Adriaensen, Dirk 2008. Functional live cell imaging of the pulmonary neuroepithelial body microenvironment. American Journal of Respiratory Cell and Molecular Biology 39 (2) , pp. 180-189. 10.1165/rcmb.2008-0011OC

Williams, S. E., Brazier, Stephen Paul, Baban, Nian, Telezhkin, Vsevolod ORCID: https://orcid.org/0000-0002-5054-8774, Muller, Carsten Theodor ORCID: https://orcid.org/0000-0003-0455-7132, Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Kemp, Paul J ORCID: https://orcid.org/0000-0003-2773-973X 2008. A structural motif in the C-terminal tail of slo1 confers carbon monoxide sensitivity to human BKCa channels. Pflugers Archiv-European Journal of Physiology 456 (3) , pp. 561-572. 10.1007/s00424-007-0439-4

Vizard, Thomas Neill, O'Keeffe, Gerard W., Gutierrez, Humberto ORCID: https://orcid.org/0000-0002-5021-8636, Kos, Claudine H., Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Davies, Alun M. ORCID: https://orcid.org/0000-0001-5841-8176 2008. Regulation of axonal and dendritic growth by the extracellular calcium-sensing receptor. Nature Neuroscience 11 (3) , pp. 285-291. 10.1038/nn2044

Gibbons, C. E., Maldonado-Perez, D., Shah, A. N., Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Ward, D. T. 2008. Calcium-sensing receptor antagonism or lithium treatment ameliorates aminoglycoside-induced cell death in renal epithelial cells. Biochimica et Biophysica Acta - Molecular Basis of Disease 1782 (3) , pp. 188-195. 10.1016/j.bbadis.2008.01.003

Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Martin, D. 2008. The role of the calcium-sensing receptor in the pathophysiology of secondary hyperparathyroidism. NDT Plus 1 (Suppl.) , i7-i11. 10.1093/ndtplus/sfm038

Timmermans, J. P., De, Proost, Pintelon, I., Wilkinson, William J., Goethals, S., Brouns, I., Van Nassauw, L., Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163, Kemp, Paul J. ORCID: https://orcid.org/0000-0003-2773-973X and Adriaensen, D. 2008. Expression of P2X receptors in LAD-2 cells and human lung mast cells [Abstract]. Purinergic Signalling 4 (S1) , S159. 10.1007/s11302-008-9116-0

Wilkinson, William J., Hanne, G., Harrison, Alexander William John, Allen, Nicholas Denby ORCID: https://orcid.org/0000-0003-4009-186X, Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Kemp, Paul J. ORCID: https://orcid.org/0000-0003-2773-973X 2008. Carbon monoxide is a rapid modulator of recombinant and native P2X2 ligand-gated ion channels [Abstract]. Purinergic Signalling 4 (S1) , p. 26. 10.1007/s11302-008-9116-0

Gamba, Gerardo and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2008. Cell biology of thiazide bone effects. Presented at: 2nd International Urolithiasis Research Symposium, Indianapolis, IN, USA, 17-18 April 2008. Published in: Evan, A. P., Williams, J. C., Lingeman, J. E. and McAteer, J. A. eds. Renal Stone Disease 2: 2nd International Urolithiasis Research Symposium, Indianapolis, Indiana, 17-18 April 2008. AIP Conference Proceedings (1049) New York: American Institute of Physics, pp. 44-52. 10.1063/1.2998060

Dvorak, Melita M., De Joussineau, Cyrille, Carter, D. Howard, Pisitkun, Trairak, Knepper, Mark A., Gamba, Gerardo, Kemp, Paul J. ORCID: https://orcid.org/0000-0003-2773-973X and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2007. Thiazide Diuretics Directly Induce Osteoblast Differentiation and Mineralized Nodule Formation by Interacting with a Sodium Chloride Co-Transporter in Bone. Journal of the American Society of Nephrology 18 (9) , pp. 2509-2516. 10.1681/ASN.2007030348

Lu, Weiqun, Worthington, Jonathan, Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163, Balment, Richard J. and McCrohan, Catherine R. 2007. Seasonal changes in peptide, receptor and ion channel mRNA expression in the caudal neurosecretory system of the European flounder (Platichthys flesus). General and Comparative Endocrinology 153 (1-3) , pp. 262-272. 10.1016/j.ygcen.2007.05.004

Lu, Weiqun, Greenwood, Michael, Dow, Louise, Yuill, Janette, Worthington, Jonathan, Brierley, Matthew J., McCrohan, Catherine R., Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Balment, Richard J. 2006. Molecular characterization and expression of Urotensin II and its receptor in the flounder (Platichthys flesus): A hormone system supporting body fluid homeostasis in euryhaline fish. Endocrinology 147 (8) , pp. 3692-3708. 10.1210/en.2005-1457

Kemp, Paul J. ORCID: https://orcid.org/0000-0003-2773-973X, Williams, Sandile E., Mason, Helen S., Wootton, Philippa, Iles, David E., Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Peers, Chris 2006. Functional proteomics of BK potassium channels: Defining the acute oxygen sensor. Chadwick, Derek J. and Goode, Jamie, eds. Signalling Pathways in Acute Oxygen Sensing: Novartis Foundation Symposium 272, Novartis Foundation Symposia, Wiley-Blackwell, pp. 141-151. (10.1002/9780470035009.ch12)

Kemp, Paul J. ORCID: https://orcid.org/0000-0003-2773-973X, Peers, Chris, Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163, Iles, David E., Mason, Helen S., Wootton, Philippa and Williams, Sandile E. 2006. In search of the acute oxygen sensor: Functional proteomics and acute regulation of large-conductance, calcium-activated potassium channels by hemeoxygenase-2. Hayashida, Yoshiaki, Gonzalez, Constancio and Kondo, Hisatake, eds. The Arterial Chemoreceptors, Vol. 580. Advances in Experimental Medicine and Biology, Springer, pp. 137-146. (10.1007/0-387-31311-7_21)

Kemp, Paul J. ORCID: https://orcid.org/0000-0003-2773-973X, Williams, Sandile E. J., Mason, Helen S., Wootton, Phillippa, Iles, David E., Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Peers, Chris 2006. General discussion II. Novartis Foundation Symposium (272) , pp. 131-140.

Ward, Donald T., Maldonado-Perez, David, Hollins, Laura and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2005. Aminoglycosides induce acute cell signaling and chronic cell death in renal cells that express the calcium-sensing receptor. Journal of the American Society of Nephrology 16 (5) , pp. 1236-1244. 10.1681/ASN.2004080631

Ward, D. T., Hamilton, K, Burnand, R., Smith, C. P., Tomlinson, D. R. and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2005. Altered expression of iron transport proteins in streptozotocin-induced diabetic rat kidney. Biochimica et Biophysica Acta - Molecular Basis of Disease 1740 (1) , pp. 79-84. 10.1016/j.bbadis.2005.01.008

Maldonado-Perez, David and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2005. The calcium-sensing receptor as a nutrient sensor [RETRACTED]. Biochemical Society Transactions 33 (1) , pp. 316-320. 10.1042/BST0330316

Williams, Sandile Elroy Johnathan, Wootton, Phillippa, Mason, Helen Sarah, Bould, Jonathan, Iles, David E., Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163, Peers, Chris and Kemp, Paul J. ORCID: https://orcid.org/0000-0003-2773-973X 2004. Hemoxygenase-2 is an oxygen sensor for a calcium-sensitive potassium channel. Science , pp. 2993-2997. 10.1126/science.1105010

Dvorak, Melita M., Siddiqua, Ashia, Ward, Donald T., Carter, D. Howard, Dallas, Sarah L., Nemeth, Edward F. and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2004. Physiological changes in extracellular calcium concentration directly control osteoblast function in the absence of calciotropic hormones. Proceedings of the National Academy of Sciences of the USA 101 (14) , pp. 5140-5145. 10.1073/pnas.0306141101

Lu, Weiqun, Dow, Louise, Gumusgoz, Sarah, Brierley, Matthew J., Warne, Justin M., McCrohan, Catherine R., Balment, Richard J. and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2004. Coexpression of corticotropin-releasing hormone and urotensin I precursor genes in the caudal neurosecretory system of the Euryhaline flounder (Platichthys flesus): A possible shared role in peripheral regulation. Endocrinology 145 (12) , pp. 5786-5797. 10.1210/en.2004-0144

Procino, Giuseppe, Carmosino, Monica, Tamma, Grazia, Gouraud, Sabine, Laera, Antonia, Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163, Svelto, Maria and Valenti, Giovanna 2004. Extracellular calcium antagonizes forskolin-induced aquaporin 2 trafficking in collecting duct cells. Kidney International 66 (6) , pp. 2245-2255. 10.1111/j.1523-1755.2004.66036.x

Brierley, M. J., Bauer, C. S., Lu, W., Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163, Balment, R. J. and McCrohan, C. R. 2004. Voltage- and Ca2+-dependent burst generation in neuroendocrine dahlgren cells in the teleost platichthys flesus. Journal of Neuroendocrinology 16 (10) , pp. 832-841. 10.1111/j.1365-2826.2004.01238.x

Moreno, E., Tovar-Palacio, C., de los Heros, P., Guzman, B., Bobadilla, N. A., Vazquez, N., Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163, Poch, E. and Gamba, G. 2004. A single nucleotide polymorphism alters the activity of the renal Na+:Cl- cotransporter and reveals a role for transmembrane segment 4 in chloride and thiazide affinity. Journal of Biological Chemistry 279 (16) , pp. 16553-16560. 10.1074/jbc.M400602200

Dvorak, Melita M. and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2004. Ca2+ as an extracellular signal in bone. Cell Calcium 35 (3) , pp. 249-255. 10.1016/j.ceca.2003.10.014

Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2004. The role of extracellular calcium in the regulation of intracellular calcium and cell function (II). Some answers and more questions. Cell Calcium 35 (3) , pp. 179-181. 10.1016/j.ceca.2003.10.007

Maldonado-Pérez, David, Breitwieser, Gerda E., Gama, Lucio, Elliott, Austin C., Ward, Donald T. and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2003. Human calcium-sensing receptor can be suppressed by antisense sequences. Biochemical and Biophysical Research Communications 311 (3) , pp. 610-617. 10.1016/j.bbrc.2003.10.041

Brierley, M. J., Ashworth, A. J., Craven, T. P., Woodburn, M., Banks, J. R., Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163, Balment, R. J. and McCrohan, C. R. 2003. Electrical activity of caudal neurosecretory neurons in seawater- and freshwater-adapted flounder: responses to cholinergic agonists. Journal of Experimental Biology 206 (22) , pp. 4011-4020. 10.1242/jeb.00631

Ferguson, Carole J., Wareing, Mark, Delannoy, Mathieu, Fenton, Robert, Mclarnon, Stuart J., Ashton, Nicholas, Cox, Alan G., Mcmahon, Raymond F. T., Garrick, Laura M., Green, Roger, Smith, Craig P. and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2003. Iron handling and gene expression of the divalent metal transporter, DMT1, in the kidney of the anemic Belgrade (b) rat. Kidney International 64 (5) , pp. 1755-1764. 10.1046/j.1523-1755.2003.00274.x

Wareing, M., Ferguson, C. J., Delannoy, M., Cox, A. G., McMahon, R. F., Green, R., Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Smith, C. P. 2003. Altered dietary iron intake is a strong modulator of renal DMT1 expression. American Journal of Physiology-Renal Physiology 285 (6) , F1050-F1059. 10.1152/ajprenal.00064.2003

Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2002. Wellcome prize lecture cell surface, ion-sensing receptors. Experimental Physiology 87 (4) , pp. 403-411. 10.1111/j.1469-445X.2002.tb00053.x

Ward, Donald T., McLarnon, Stuart J. and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2002. Aminoglycosides increase intracellular calcium levels and ERK activity in proximal tubular OK cells expressing the extracellular calcium-sensing receptor. Journal of the American Society of Nephrology , pp. 1481-1489. 10.1097/01.ASN.0000015623.73739.B8

McLarnon, Stuart J., Holden, Darren, Ward, Donald T., Jones, Malcolm N., Elliott, Austin C. and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2002. Aminoglycoside antibiotics induce pH-sensitive activation of the calcium-sensing receptor. Biochemical and Biophysical Research Communications 297 (1) , pp. 71-77. 10.1016/S0006-291X(02)02133-2

Konstas, A. A., Shearwin-Whyatt, L. M., Fotia, A. B., Degger, B., Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163, Cook, D. I., Korbmacher, C. and Kumar, S. 2002. Regulation of the epithelial sodium channel by N4WBP5A, a novel Nedd4/Nedd4-2-interacting protein. Journal of Biological Chemistry 277 (33) , pp. 29406-29416. 10.1074/jbc.M203018200

McLarnon, Stuart J. and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2002. Physiological and pharmacological agonists of the extracellular Ca2+-sensing receptor. European Journal of Pharmacology 447 (2-3) , pp. 271-278. 10.1016/S0014-2999(02)01849-6

Ward, Donald and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2002. Renal physiology of the extracellular calcium-sensing receptor. Pflugers Archiv European Journal of Physiology 445 (2) , pp. 169-176. 10.1007/s00424-002-0914-x

Ferguson, C. J., Wareing, M., Ward, D. T., Green, R., Smith, C. P. and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2001. Cellular localization of divalent metal transporter DMT-1 in rat kidney. American Journal of Physiology-Renal Physiology 280 (5) , F803-F814.

Ward, D. T., Yau, S. K., Mee, A. P., Mawer, E. B., Miller, C. A., Garland, H. O. and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2001. Functional, molecular, and biochemical characterization of streptozotocin-induced diabetes. Journal of the American Society of Nephrology 12 (4) , pp. 779-790.

Wareing, Mark, Ferguson, Carole J., Green, Roger, Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Smith, Craig P. 2000. In vivo characterization of renal iron transport in the anaesthetized rat. The Journal of Physiology 524 (2) , pp. 581-586. 10.1111/j.1469-7793.2000.00581.x

Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163, Traebert, Martin, Ward, Donald T., Kaissling, Brigitte, Biber, J., Hebert, Steven C. and Murer, Heini 2000. Dietary phosphate and parathyroid hormone alter the expression of the calcium-sensing receptor (CaR) and the Na + -dependent P i transporter (NaPi-2) in the rat proximal tubule. Pflugers Archiv European Journal of Physiology 441 (2-3) , pp. 379-387. 10.1007/s004240000436

Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2000. Calcium ions as extracellular, first messengers. Zeitschrift fur Kardiologie -Supplement- 89 (Supp 2) , pp. 9-14.