Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Browse by All Cardiff Authors

[up] Up a level
Number of items: 34.

Antwi, Frank D., Awad, Tufaha, Larin, Meghan, Heesom, Kate, Lewis, Phil, Reddell, Paul, Poghosyan, Zaruhi ORCID: https://orcid.org/0000-0003-4966-7618, Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241, Moseley, Ryan ORCID: https://orcid.org/0000-0002-2812-6735 and Knäuper, Vera ORCID: https://orcid.org/0000-0002-3965-9924 2024. Tigilanol tiglate-induced changes in secretome profiles alter c-Met phosphorylation and cell surface protein expression in H357 head and neck cancer cells. Cells 13 (11) , 982. 10.3390/cells13110982
file

Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241, Green, Joanna, Laffafian, Iraj, Lewis, Kimberly J. and Hallett, Maurice B. ORCID: https://orcid.org/0000-0001-8197-834X 2024. Intraphagosomal free Ca2+changes during phagocytosis. International Journal of Molecular Sciences 25 (8) , 4254. 10.3390/ijms25084254
file

Bauer, Lea, Edwards, Jessica, Heil, Andreas ORCID: https://orcid.org/0000-0002-9536-5402, Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241, Biebermann, Heike, Aeschlimann, Daniel ORCID: https://orcid.org/0000-0003-0930-7706 and Knauper, Vera ORCID: https://orcid.org/0000-0002-3965-9924 2024. Mesenchymal transglutaminase 2 activates epithelial ADAM17: link to G-protein coupled receptor 56 (ADGRG1) signalling. International Journal of Molecular Sciences 25 (4) , 2329. 10.3390/ijms25042329
filefile

Brown, Sarah V., Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226 and Waddington, Rachel J. ORCID: https://orcid.org/0000-0001-5878-1434 2022. Identifying the efficacy of extracellular vesicles in osteogenic differentiation: an EV-Lution in regenerative medicine. Frontiers in Dental Medicine 3 , 849724. 10.3389/fdmed.2022.849724
file

Al-Jumaa, Maha, Hallett, Maurice B ORCID: https://orcid.org/0000-0001-8197-834X and Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241 2020. Cell surface topography controls phagocytosis and cell spreading: the membrane reservoir in neutrophils. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 12 , 118832. 10.1016/j.bbamcr.2020.118832
filefilefilefile

Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241 and Hallett, Maurice B. ORCID: https://orcid.org/0000-0001-8197-834X 2020. Calpain activation by Ca2+ and its role in phagocytosis. Hallett, Maurice B., ed. Molecular and Cellular Biology of Phagocytosis, Vol. 1246. Advances in Experimental Medicine and Biology, Switzerland: Springer, pp. 129-151. (10.1007/978-3-030-40406-2_8)

Roberts, Rhiannon E., Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241 and Hallett, Maurice B. ORCID: https://orcid.org/0000-0001-8197-834X 2020. Membrane tension and the role of ezrin during phagocytosis. Hallett, Maurice B. ORCID: https://orcid.org/0000-0001-8197-834X, ed. Molecular and Cellular Biology of Phagocytosis, Vol. 1246. Advances in Experimental Medicine and Biology, Switzerland: Springer, pp. 83-102. (10.1007/978-3-030-40406-2_6)

Hallett, Maurice B. ORCID: https://orcid.org/0000-0001-8197-834X, Roberts, Rhiannon E. and Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241 2019. Optical methods for the measurement and manipulation of cytosolic calcium signals in neutrophils. Neutrophil, Vol. 2087. Methods in Molecular Biology, New York: Humana Press, pp. 191-205. (10.1007/978-1-0716-0154-9_14)

Jumaa, Maha A. Al, Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241 and Hallett, Maurice B. ORCID: https://orcid.org/0000-0001-8197-834X 2017. Topographical interrogation of the living cell surface reveals its role in rapid cell shape changes during phagocytosis and spreading. Scientific Reports 7 , -. 10.1038/s41598-017-09761-6
filefile

Adamczyk, Magdalena ORCID: https://orcid.org/0000-0002-7405-5157, Griffiths, Rhiannon, Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241, Knauper, Vera ORCID: https://orcid.org/0000-0002-3965-9924 and Aeschlimann, Daniel ORCID: https://orcid.org/0000-0003-0930-7706 2015. P2X7 receptor activation regulates rapid unconventional export of transglutaminase-2. Journal of Cell Science 128 (24) , pp. 4615-4628. 10.1242/jcs.175968
filefile

Wanger, Tim M., Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241, Collins, Anne, Maitland, Norman J., Poghosyan, Zaruhi and Knauper, Vera ORCID: https://orcid.org/0000-0002-3965-9924 2015. Differential regulation of TROP2 release by PKC isoforms through vesicles and ADAM17. Cellular Signalling 27 (7) , pp. 1325-1335. 10.1016/j.cellsig.2015.03.017
filefile

Lewis, Kimberley J., Masterman, Benjamin, Laffafian, Iraj, Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241, Campbell, Jennie S. and Hallett, Maurice B. ORCID: https://orcid.org/0000-0001-8197-834X 2014. Minimal impact electro-injection of cells undergoing dynamic shape change reveals calpain activation. BBA - Molecular Cell Research 1843 (6) , pp. 1182-1187. 10.1016/j.bbamcr.2014.02.020
filefile

Hallett, Maurice ORCID: https://orcid.org/0000-0001-8197-834X, Al-Jumaa, Maha and Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241 2014. Optical methods for the measurement and manipulation of cytosolic calcium signals in neutrophils. Quinn, Mark T. and DeLeo, Frank R., eds. Neutrophil Methods and Protocols, Methods in Molecular Biology, vol. 1124. Humana Press, pp. 107-120. (10.1007/978-1-62703-845-4_8)

Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241, Francis, Robert J. and Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X 2013. Ca2+ and calpain control membrane expansion during rapid cell spreading of neutrophils. Journal of Cell Science 126 (20) , pp. 4627-4635. 10.1242/jcs.124917

McDonald, Jacqueline U., Cortini, Andrea, Rosas, Marcela ORCID: https://orcid.org/0000-0002-9442-9638, Fossati-Jimack, Liliane, Ling, Guang Sheng, Lewis, Kimberley, Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241, Liddiard, Kate ORCID: https://orcid.org/0000-0002-0953-1997, Brown, Gordon D., Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711, Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X, Botto, Marina and Taylor, Philip Russel ORCID: https://orcid.org/0000-0003-0163-1421 2011. In vivo functional analysis and genetic modification of in vitro-derived mouse neutrophils. The FASEB Journal 25 (6) , pp. 1972-1982. 10.1096/fj.10-178517

Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241 and Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X 2011. Optical complexities of living cytoplasm - implications for live cell imaging and photo-micromanipulation techniques. Journal of Microscopy 241 (3) , pp. 221-224. 10.1111/j.1365-2818.2010.03451.x

Lewis, Kimberley, Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241 and Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X 2011. The role of calpain translocation in neutrophil spreading [Abstract]. European Journal of Clinical Investigation 41 (s1) , p. 47. 10.1111/j.1365-2362.2011.02508.x

Ishak, Reezal ORCID: https://orcid.org/0000-0001-7518-7365, Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241 and Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X 2011. Calpain-1: investigating its role in murine neutrophils [Abstract]. European Journal of Clinical Investigation 41 (s1) , p. 24. 10.1111/j.1365-2362.2011.02508.x

Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X and Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241 2011. A trick of the light: the optical properties of living cytoplasm which can mislead. Integrative Biology 3 (3) , pp. 180-184. 10.1039/c0ib00039f

Elumalai, G. L., Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241 and Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X 2011. Ezrin and talin relocates from the plasma membrane to cytosol during neutrophil extravasation [Abstract]. European Journal of Clinical Investigation 41 (s1) , p. 47. 10.1111/j.1365-2362.2011.02508.x

Brasen, Jens Christian, Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241 and Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X 2010. A reporter of UV intensity delivered to the cytosol during photolytic uncaging. Biophysical Journal 98 (7) , L25-L27. 10.1016/j.bpj.2009.12.4271
file

Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241, Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 and Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X 2009. Translocation or just location? Pseudopodia affect fluorescent signals. Journal of Cell Biology 184 (2) , pp. 197-203. 10.1083/jcb.200806047
file

Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X, Von Ruhland, Christopher John and Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241 2008. Chemotaxis and the cell surface-area problem [Letter]. Nature Reviews Molecular Cell Biology 9 (8) , p. 662. 10.1038/nrm2419-c1

Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241 and Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X 2007. Leukocyte membrane 'expansion': a central mechanism for leukocyte extravasation. Journal of leukocyte biology 81 (5) , pp. 1160-1164. 10.1189/jlb.1106710

Hillson, E. J., Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241 and Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X 2007. Optical methods for the measurement and manipulation of cytosolic free calcium in neutrophils. Quinn, M. T., DeLeo, F. R. and Bokoch, G. M., eds. Neutrophil Methods and Protocols, Methods in Molecular Biology, vol. 412. Totowa, NJ: Humana Press, pp. 125-137. (10.1007/978-1-59745-467-4_10)

Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X, Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241 and Tian, Wei 2006. Localised PtdIns(3,4,5)P3 or PtdIns(3,4)P2 at the phagocytic cup is required for both phagosome closure and Ca2+ signalling in HL60 neutrophils. Journal of Cell Science 119 (3) , pp. 443-51. 10.1242/jcs.02756

Ayub, Khurram, Laffaffian, Iraq, Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241 and Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X 2004. Ca2+ influx shutdown in neutrophils induced by Fas (CD95) cross-linking. Immunology 112 (3) , pp. 454-460. 10.1111/j.1365-2567.2004.01899.x

Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Turkes, Atilla, Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241, Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496, Mason, Malcolm David ORCID: https://orcid.org/0000-0003-1505-2869 and Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X 2004. Adhesion and signaling by B cell-derived exosomes: the role of integrins. The FASEB Journal 18 , pp. 977-979. 10.1096/fj.03-1094fje

Tian, Wei, Laffafian, Iraj, Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241 and Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X 2003. Exclusion of exogenous phosphatidylinositol-3,4,5-trisphosphate from neutrophil-polarizing pseudopodia: stabilization of the uropod and cell polarity. EMBO Reports 4 (10) , pp. 982-988. 10.1038/sj.embor.embor947

Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X, Laffafian, Iraj and Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241 2003. Phagosomal oxidative activity during beta2 integrin (CR3)-mediated phagocytosis by neutrophils is triggered by a non-restricted Ca2+ signal: Ca2+ controls time not space. Journal of Cell Science 116 (14) , pp. 2857-65. 10.1242/jcs.00499

Morris, M. R., Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241, Laffafian, Iraj and Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X 2003. Phagocytosis by inflammatory phagocytes; experimental strategies for stimulation and quantification. Winyard, P. G. and Willoughby, D. A., eds. Inflammation Protocols, Methods in Molecular Biology, vol. 225. Totowa, NJ: Humana Press, pp. 35-46. (10.1385/1-59259-374-7:35)

Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X, Cole, C. and Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241 2003. Detection and visualization of oxidase activity in phagocytes. Winyard, P. G. and Willoughby, D. A., eds. Inflammation Protocols, Vol. 225. Methods in Molecular Biology, Totowa, NJ: Humana Press, pp. 61-67. (10.1385/1-59259-374-7:61)

Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241, Laffafian, Iraj, Morris, Mary Rachel and Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X 2003. Cytosolic Ca2+ measurement and imaging in inflammatory cells. Winyard, Paul G. and Willoughby, Derek A., eds. Inflammation Protocols, Methods in Molecular Biology, vol. 255. Totowa, NJ: Humana Press, pp. 47-63. (10.1385/1-59259-374-7:47)

Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X and Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241 2002. Cytosolic free Ca(2+) changes and calpain activation are required for beta integrin-accelerated phagocytosis by human neutrophils. The Journal of Cell Biology 159 (1) , pp. 181-9. 10.1083/jcb.200206089

This list was generated on Mon Nov 3 15:25:34 2025 GMT.


Maintained by Cardiff University IT