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Number of items: 16.

Williams, Jason S., Higgins, Adam T. ORCID: https://orcid.org/0000-0002-2906-8151, Stott, Katie J., Thomas, Carly, Farrell, Lydia, Bonnet, Cleo, Peneva, Severena, Derrick, Anna V., Hay, Trevor, Wang, Tianqi, Morgan, Claire, Dwyer, Sarah, D'Ambrogio, Joshua, Hogan, Catherine ORCID: https://orcid.org/0000-0002-1012-0896, Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 and Dyson, Paul 2024. Enhanced bacterial cancer therapy delivering therapeutic RNA interference of c-Myc. Cell & Bioscience 14 (38) 10.1186/s13578-024-01206-8
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Tornillo, Giusy, Warrington, Lauren, Kendrick, Howard, Higgins, Adam T. ORCID: https://orcid.org/0000-0002-2906-8151, Hay, Trevor, Beck, Sam and Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 2024. Conditional in vivo deletion of LYN kinase has little effect on a BRCA1 loss-of-function-associated mammary tumour model. Disease Models and Mechanisms 17 (1) , dmm050211. 10.1242/dmm.050211
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Ordonez, Liliana, Tornillo, Giusy, Kendrick, Howard, Hay, Trevor and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2023. NOTCH and AKT signalling interact to drive mammary tumour heterogeneity. Cancers 15 (17) , 4324. 10.3390/cancers15174324
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Ordonez, Liliana D, Hay, Trevor, McEwen, Robert, Polanska, Urszula M, Hughes, Adina, Delpuech, Oona, Cadogan, Elaine, Powell, Steve, Dry, Jonathan, Tornillo, Giusy, Silcock, Lucy, Leo, Elisabetta, O'Connor, Mark J, Clarke, Alan R ORCID: https://orcid.org/0000-0002-4281-426X and Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 2019. Rapid activation of epithelial-mesenchymal transition drives PARP inhibitor resistance in Brca2-mutant mammary tumours. Oncotarget 10 (27) , pp. 2586-2606. 10.18632/oncotarget.26830
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Mohamed, Noha-Ehssan, Hay, Trevor, Reed, Karen R. ORCID: https://orcid.org/0000-0002-7467-1718, Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 and Clarke, Alan R. ORCID: https://orcid.org/0000-0002-4281-426X 2019. APC2 is critical for ovarian WNT signalling control, fertility and tumour suppression. BMC Cancer 19 , 677. 10.1186/s12885-019-5867-y
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Johnson, Charlotte E. ORCID: https://orcid.org/0000-0003-1954-5142, Dunlop, Elaine A. ORCID: https://orcid.org/0000-0002-9209-7561, Seifan, Sara, McCann, Henry D., Hay, Trevor, Parfitt, Geraint J. ORCID: https://orcid.org/0000-0002-8704-7906, Jones, Ashley T., Giles, Peter J. ORCID: https://orcid.org/0000-0003-3143-6854, Shen, Ming H. ORCID: https://orcid.org/0000-0002-3891-7231, Sampson, Julian R. ORCID: https://orcid.org/0000-0002-2902-2348, Errington, Rachel J. ORCID: https://orcid.org/0000-0002-8016-4376, Davies, D. Mark and Tee, Andrew R. ORCID: https://orcid.org/0000-0002-5577-4631 2018. Loss of tuberous sclerosis complex 2 sensitizes tumors to nelfinavir−bortezomib therapy to intensify endoplasmic reticulum stress-induced cell death. Oncogene 37 , pp. 5913-5925. 10.1038/s41388-018-0381-2
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Bird, Thomas G., Müller, Miryam, Boulter, Luke, Vincent, David F., Ridgway, Rachel A., Lopez-Guadamillas, Elena, Lu, Wei-Yu, Jamieson, Thomas, Govaere, Olivier, Campbell, Andrew D., Ferreira-Gonzalez, Sofía, Cole, Alicia M., Hay, Trevor, Simpson, Kenneth J., Clark, William, Hedley, Ann, Clarke, Mairi ORCID: https://orcid.org/0000-0002-4281-426X, Gentaz, Pauline, Nixon, Colin, Bryce, Steven, Kiourtis, Christos, Sprangers, Joep, Nibbs, Robert J. B., Van Rooijen, Nico, Bartholin, Laurent, McGreal, Steven R., Apte, Udayan, Barry, Simon T., Iredale, John P., Clarke, Alan R. ORCID: https://orcid.org/0000-0002-4281-426X, Serrano, Manuel, Roskams, Tania A., Sansom, Owen J. and Forbes, Stuart J. 2018. TGFβ inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence. Science Translational Medicine 10 (454) , eaan1230. 10.1126/scitranslmed.aan1230

Lu, Wei-Yu, Bird, Thomas G., Boulter, Luke, Tsuchiya, Atsunori, Cole, Alicia M., Hay, Trevor, Guest, Rachel V., Wojtacha, Davina, Man, Tak Yung, Mackinnon, Alison, Ridgway, Rachel A., Kendall, Timothy, Williams, Michael J., Jamieson, Thomas, Raven, Alex, Hay, David C., Iredale, John P., Clarke, Alan R. ORCID: https://orcid.org/0000-0002-4281-426X, Sansom, Owen J. and Forbes, Stuart J. 2015. Hepatic progenitor cells of biliary origin with liver repopulation capacity. Nature Cell Biology 17 (8) , pp. 971-983. 10.1038/ncb3203

Tangudu, N. K., Verma, V. K., Clemons, T. D., Beevi, S. S., Hay, Trevor, Mahidhara, G., Raja, Meera, Nair, R. A., Alexander, L. E., Patel, A. B., Jose, J., Smith, N. M., Zdyrko, B., Bourdoncle, A., Luzinov, I., Iyer, K. S., Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X and Dinesh Kumar, L. 2015. RNA interference using c-Myc-conjugated nanoparticles suppresses breast and colorectal cancer models. Molecular Cancer Therapeutics 14 (5) , pp. 1259-1269. 10.1158/1535-7163.MCT-14-0970

Bird, T., Cole, A., Hay, Trevor James, Iredale, J. P., Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X, Sansom, O. J. and Forbes, S. J. 2009. A novel inducible genetic murine model of hepatocyte senescence causes a massive hepatic oval cell response and complete hepatocyte replacement from endogenous progenitor cells [Abstract]. Journal of Hepatology 50 (S1) , S3.

Hay, Trevor James, Matthews, J. R., Pietzka, Lucie Charlotte, Lau, A., Cranston, A., Nygren, A. O. H., Douglas-Jones, A., Smith, G. C. M., Martin, N. M. B., O'Connor, M. and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2009. Poly(ADP-ribose) polymerase-1 inhibitor treatment regresses autochthonous brca2/p53-mutant mammary tumors in vivo and delays tumor relapse in combination with carboplatin. Cancer Research 69 (9) , pp. 3850-3855. 10.1158/0008-5472.CAN-08-2388

Meniel, Valerie, Hay, Trevor, Douglas-Jones, Anthony Gordon, Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010 and Clarke, Alan R. ORCID: https://orcid.org/0000-0002-4281-426X 2005. Mutations in Apc and p53 synergize to promote mammary neoplasia. Cancer Research 65 (24) , pp. 410-6.

Hay, Trevor, Jenkins, Helen, Sansom, Owen J ORCID: https://orcid.org/0000-0001-9540-3010, Martin, Niall M. B., Smith, Graeme C. M. and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2005. Efficient deletion of normal Brca2-deficient intestinal epithelium by poly(ADP-ribose) polymerase inhibition models potential prophylactic therapy. Cancer Research 65 (22) , p. 10145. 10.1158/0008-5472.CAN-05-1186

Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X and Hay, Trevor 2005. DNA damage hypersensitivity in cells lacking BRCA2: a review of in vitro and in vivo data. Biochemical Society Transactions 33 (4) , pp. 715-717. 10.1042/BST0330715

Hay, Trevor, Patrick, Teresa, Winton, Douglas, Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010 and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2005. Brca2 deficiency in the murine small intestine sensitizes to p53-dependent apoptosis and leads to the spontaneous deletion of stem cells. Oncogene 24 (23) , pp. 3842-3846. 10.1038/sj.onc.1208533

Gallagher, Ronald C. J., Hay, Trevor, Meniel, Valerie, Naughton, Catherine, Anderson, Thomas J., Shibata, Hiroyuki, Ito, Masaki, Clevers, Hans, Noda, Tetsuo, Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010, Mason, John O. and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2002. Inactivation of Apc perturbs mammary development, but only directly results in acanthoma in the context of Tcf-1 deficiency. Oncogene 21 (42) , pp. 6446-6457. 10.1038/sj.onc.1205892

This list was generated on Sat Nov 8 11:32:50 2025 GMT.


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