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Number of items: 35.

Tornillo, Giusy, Warrington, Lauren, Kendrick, Howard, Higgins, Adam T. ORCID:, Hay, Trevor, Beck, Sam and Smalley, Matthew J. ORCID: 2024. Conditional in vivo deletion of LYN kinase has little effect on a BRCA1 loss-of-function-associated mammary tumour model. Disease Models and Mechanisms 17 (1) , dmm050211. 10.1242/dmm.050211

Ordonez, Liliana, Tornillo, Giusy, Kendrick, Howard, Hay, Trevor and Smalley, Matthew John ORCID: 2023. NOTCH and AKT signalling interact to drive mammary tumour heterogeneity. Cancers 15 (17) , 4324. 10.3390/cancers15174324

Morgan, Huw J., Rees, Elise, Lanfredini, Simone ORCID:, Powell, Kate A., Gore, Jasmine, Gibbs, Alex, Lovatt, Charlotte, Davies, Gemma E., Olivero, Carlotta ORCID:, Shorning, Boris Y., Tornillo, Giusy, Tonks, Alex ORCID:, Darley, Richard ORCID:, Wang, Eddie C.Y. ORCID: and Patel, Girish K. 2022. CD200 ectodomain shedding into the tumor microenvironment leads to NK cell dysfunction and apoptosis. Journal of Clinical Investigation 132 (21) , e150750. 10.1172/JCI150750

Routledge, Daniel, Rogers, Sally, Ono, Yosuke, Brunt, Lucy, Meniel, Valerie, Tornillo, Giusy, Ashktorab, Hassan, Phesse, Toby J ORCID: and Scholpp, Steffen 2022. The scaffolding protein flot2 promotes cytoneme-based transport of wnt3 in gastric cancer. eLife 11 , e77376. 10.7554/elife.77376

Dimitriou, Pantelitsa, Li, Jin ORCID:, Tornillo, Giusy, Smalley, Matthew ORCID: and Barrow, David ORCID: 2022. Droplet incubator: a new droplet-based model to investigate living cell-synthetic cell interactions. Presented at: MicroTAS 2022, Hangzhou, China, 23-27 October 2022.

Castro, Jessica, Tornillo, Giusy, Ceada, Gerardo, Ramos-Neble, Beatriz, Bravo, Marlon, Ribo', Marc, Vilanova, Maria, Smalley, Matthew ORCID: and Benito, Antoni 2021. A nuclear-directed ribonuclease variant targets cancer stem cells and inhibits migration and invasion of breast cancer cells. Cancers 13 (17) , 4350. 10.3390/cancers13174350

Metcalfe, Richard S., Kemp, Rachael, Heffernan, Shane M., Churm, Rachel, Chen, Yung-Chih, Ruffino, José S., Conway, Gillian E., Tornillo, Giusy and Orange, Samuel T. 2021. Anti-carcinogenic effects of exercise-conditioned human serum: evidence, relevance and opportunities. European Journal of Applied Physiology and Occupational Physiology 121 (8) , 2107–2124. 10.1007/s00421-021-04680-x

Dimitriou, Pantelitsa, Li, Jin ORCID:, Tornillo, Giusy, McCloy, Thomas and Barrow, David ORCID: 2021. Droplet microfluidics for tumor drug-related studies and programmable artificial cells. Global Challenges 5 (7) , 2000123. 10.1002/gch2.202000123

Ordonez, Liliana D., Melchor, Lorenzo, Greenow, Kirsty R., Kendrick, Howard, Tornillo, Giusy, Bradford, James, Giles, Peter ORCID: and Smalley, Matthew J. ORCID: 2021. Reproductive history determines ErbB2 locus amplification, WNT signalling and tumour phenotype in a murine breast cancer model. Disease Models and Mechanisms 14 (5) , dmm048736. 10.1242/dmm.048736

Newland, Ben ORCID:, Varricchio, Carmine ORCID:, Körner, Yvonne, Hoppe, Franziska, Taplan, Christian, Newland, Heike ORCID:, Eigel, Dimitri, Tornillo, Giusy, Pette, Dagmar, Brancale, Andrea ORCID:, Welzel, Petra B., Seib, F. Philipp and Werner, Carsten 2020. Focal drug administration via heparin-containing cryogel microcarriers reduces cancer growth and metastasis. Carbohydrate Polymers 245 , 116504. 10.1016/j.carbpol.2020.116504

French, Rhiannon and Tornillo, Giusy 2019. Heterogeneity of mammary stem cells. Advances in Experimental Medicine and Biology 1169 , pp. 119-140. 10.1007/978-3-030-24108-7_7

Menendez Gonzalez, Juan Bautista, Vukovic, Milica, Abdelfattah, Ali, Saleh, Lubaid, Almotiri, Alhomidi, Thomas, Leigh-anne, Agirre-Lizaso, Alona, Azevedo, Aleksandra, Menezes, Ana Catarina, Tornillo, Giusy, Edkins, Sarah ORCID:, Kong, Kay, Giles, Peter ORCID:, Anjos-Afonso, Fernando, Tonks, Alex ORCID:, Boyd, Ashleigh S., Kranc, Kamil R. and Rodrigues, Neil P. ORCID: 2019. Gata2 as a crucial regulator of stem cells in adult hematopoiesis and acute myeloid leukemia. Stem Cell Reports 13 (2) , pp. 291-306. 10.1016/j.stemcr.2019.07.005

Ordonez, Liliana D, Hay, Trevor, McEwen, Robert, Polanska, Urszula M, Hughes, Adina, Delpuech, Oona, Cadogan, Elaine, Powell, Steve, Dry, Jonathan, Tornillo, Giusy, Silcock, Lucy, Leo, Elisabetta, O'Connor, Mark J, Clarke, Alan R ORCID: and Smalley, Matthew J. ORCID: 2019. Rapid activation of epithelial-mesenchymal transition drives PARP inhibitor resistance in Brca2-mutant mammary tumours. Oncotarget 10 (27) , pp. 2586-2606. 10.18632/oncotarget.26830

Tornillo, Giusy, Knowlson, Catherine, Kendrick, Howard, Cooke, Joe, Mirza, Hasan, Aurrekoetxea-Rodriguez, Iskander, d.M. Vivanco, Maria, Buckley, Niamh E., Grigoriadis, Anita and Smalley, Matthew J. ORCID: 2018. Dual mechanisms of LYN kinase dysregulation drive aggressive behaviour in breast cancer cells. Cell Reports 25 (13) , pp. 3674-3692. 10.1016/j.celrep.2018.11.103

Moriconi, Chiara ORCID:, Palmieri, Valentina, Tornillo, Giusy, Fillmore, Helen, Pilkington, Geoffrey J. and Gumbleton, Mark ORCID: 2018. Caveolin-1, a driver of invasive phenotype in in-vitro 3D-spheroid assays comprised of high grade GBM cells association with an AKT-inhibited phenotype. Neuro-Oncology 20 (S1) , i13-i13. 10.1093/neuonc/nox238.058

Soady, Kelly J., Tornillo, Giusy, Kendrick, Howard, Meniel, Valerie, Olijnyk-Dallis, Daria, Morris, Joanna S., Stein, Torstein, Gusterson, Barry A., Isacke, Clare M. and Smalley, Matthew J. ORCID: 2017. Receptor protein tyrosine phosphatase PTPRB negatively regulates FGF2-dependent branching morphogenesis. Development 144 (20) , pp. 3777-3788. 10.1242/dev.149120

Moriconi, Chiara ORCID:, Palmieri, Valentina, di Santo, Riccardo, Tornillo, Giusy, Papi, Massimiliano, Pilkington, Geoff, De Spirito, Marco and Gumbleton, Mark ORCID: 2017. INSIDIA: a FIJI macro delivering high-throughput and high-content spheroid invasion analysis. Biotechnology Journal 12 (10) , 1700140. 10.1002/biot.201700140

Moriconi, Chiara ORCID:, Palmieri, Valentina, Tornillo, Giusy, Fillmore, Helen, Pilkington, Geoff and Gumbleton, Mark ORCID: 2017. Caveolin-1 implicated as a pro-invasive gene in high-grade glioma cell models: implementation of a 3d spheroid matrix invasion assay. Neuro-Oncology 19 (S1) , i21-i22. 10.1093/neuonc/now293.080

Tornillo, Giusy and Smalley, Matthew John ORCID: 2015. ERrrr...Where are the progenitors? Hormone receptors and mammary cell heterogeneity. Journal of Mammary Gland Biology and Neoplasia 20 (1) , pp. 63-73. 10.1007/s10911-015-9336-1

Leal, Maria del Pilar Camacho, Sciortino, Marianna, Tornillo, Giusy, Colombo, Shana, Defilippi, Paola and Cabodi, Sara 2015. p130Cas/BCAR1 scaffold protein in tissue homeostasis and pathogenesis. Gene 562 (1) , pp. 1-7. 10.1016/j.gene.2015.02.027

Fusella, Federica, Ferretti, Roberta, Recupero, Daniele, Rocca, Stefania, Di Savino, Augusta, Tornillo, Giusy, Silengo, Lorenzo, Turco, Emilia, Cabodi, Sara, Provero, Paolo, Pandolfi, Pier Paolo, Sapino, Anna, Tarone, Guido and Brancaccio, Mara 2014. Morgana acts as a proto-oncogene through inhibition of a ROCK-PTEN pathway. The Journal of Pathology 234 (2) , pp. 152-163. 10.1002/path.4341

Pincini, Alessandra, Tornillo, Giusy, Orso, Francesca, Sciortino, Marianna, Bisaro, Brigitte, Camacho Leal, Maria del Pilar, Lembo, Antonio, Brizzi, Maria Felice, Turco, Emilia, De Pitta, Cristiano, Provero, Paolo, Medico, Enzo, Defilippi, Paola, Taverna, Daniela and Cabodi, Sara 2014. Identification of p130Cas/ErbB2-dependent invasive signatures in transformed mammary epithelial cells. Cell Cycle 12 (15) , pp. 2409-2422. 10.4161/cc.25415

Tornillo, Giusy, Defilippi, Paola and Cabodi, Sara 2014. Cas proteins: dodgy scaffolding in breast cancer. Breast Cancer Research 16 (5) , 443. 10.1186/s13058-014-0443-5

Tornillo, Giusy and Cabodi, Sara 2014. 3D mammary colony-forming cell assay. Bio-Protocol 4 (7)

Saoncella, Stefania, Tassone, Beatrice, Deklic, Erika, Avolio, Fabio, Jon, Cristina, Tornillo, Giusy, De Luca, Elisa, Di Iorio, Enzo, Piva, Roberto, Cabodi, Sara, Turco, Emilia, Pandolfi, Pier Paolo and Calautti, Enzo 2014. Nuclear Akt2 opposes limbal keratinocyte stem cell self-renewal by repressing a FOXO-mTORC1 signaling pathway. Stem Cells 32 (3) , pp. 754-769. 10.1002/stem.1565

Tornillo, Giusy, Elia, Angela Rita, Castellano, Isabella, Spadaro, Michela, Bernabei, Paola, Bisaro, Brigitte, Camacho-Leal, Maria del Pilar, Pincini, Alessandra, Provero, Paolo, Sapino, Anna, Turco, Emilia, Defilippi, Paola and Cabodi, Sara 2013. p130Cas alters the differentiation potential of mammary luminal progenitors by deregulating c-Kit activity. Stem Cells 31 (7) , pp. 1422-1433. 10.1002/stem.1403

Leal, Maria del Pilar Camacho, Pincini, Alessandra, Tornillo, Giusy, Fiorito, Elisa, Bisaro, Brigitte, Di Luca, Elisa, Turco, Emilia, Defilippi, Paola and Cabodi, Sara 2012. p130Cas over-expression impairs mammary branching morphogenesis in response to Estrogen and EGF. Plos One 7 (12) , e49817. 10.1371/journal.pone.0049817

Bisaro, Brigitte, Montani, Maura, Konstantinidou, Georgia, Marchini, Cristina, Pietrella, Lucia, Iezzi, Manuela, Galie, Mirco, Orso, Francesca, Camporeale, Annalisa, Colombo, Shana M., Di Stefano, Paola, Tornillo, Giusy, Camacho-Leal, Maria P., Turco, Emilia, Taverna, Daniela, Cabodi, Sara, Amici, Augusto and Defilippi, Paola 2012. p130Cas/Cyclooxygenase-2 axis in the control of mesenchymal plasticity of breast cancer cells. Breast Cancer Research 14 (5) , R137. 10.1186/bcr3342

D'Agostino, Massimo, Tornillo, Giusy, Caporaso, Maria Gabriella, Barone, Maria Vittoria, Ghigo, Eric, Bonatti, Stefano and Mottola, Giovanna 2011. Ligand of Numb proteins LNX1p80 and LNX2 interact with the human glycoprotein CD8 alpha and promote its ubiquitylation and endocytosis. Journal of Cell Science 124 (21) , pp. 3545-3556. 10.1242/jcs.081224

Fusella, F., Ferretti, R., Di Savino, A., Tornillo, Giusy, Cabodi, S., Pandolfi, P. P., Tarone, G. and Brancaccio, M. 2011. P11.46 Morgana overexpression confers resistance from apoptotic cell death. Febs Journal 278 (Supp 1) , p. 207. 10.1111/j.1742-4658.2011.08137.x

Camacho Leal, M. P., Fiorito, E., Pincini, A. and Tornillo, Giusy 2011. p130Cas overexpression regulates normal mammary branching morphogenesis through estrogen receptor-alpha/ERk1/2 dependent signaling. Febs Journal 278 (Supp 1) , p. 427. 10.1111/j.1742-4658.2011.08137.x

Tornillo, Giusy, Bisaro, Brigitte, Camacho-Leal, Maria del Pilar, Galie, Mirco, Provero, Paolo, Di Stefano, Paola, Turco, Emilia, Defilippi, Paola and Cabodi, Sara 2011. p130Cas promotes invasiveness of three-dimensional ErbB2-transformed mammary acinar structures by enhanced activation of mTOR/p70S6K and Rac1. European Journal of Cell Biology 90 (2-3) , pp. 237-248. 10.1016/j.ejcb.2010.09.002

Di Stefano, Paola, Leal, Maria Pilar Camacho, Tornillo, Giusy, Bisaro, Brigitte, Repetto, Daniele, Pincini, Alessandra, Santopietro, Emanuela, Sharma, Nanaocha, Turco, Emilia, Cabodi, Sara and Defilippi, Paola 2011. The adaptor proteins p140CAP and p130CAS as molecular hubs in cell migration and invasion of cancer cells. American Journal of Cancer Research 1 (5) , pp. 663-673.

Cabodi, Sara, Tinnirello, Agata, Bisaro, Brigitte, Tornillo, Giusy, Camacho-Leal, Maria del Pilar, Forni, Guido, Cojoca, Rodica, Iezzi, Manuela, Amici, Augusto, Montani, Maura, Eva, Alessandra, Di Stefano, Paola, Muthuswamy, Senthil K., Tarone, Guido, Turco, Emilia and Defilippi, Paola 2010. p130Cas is an essential transducer element in ErbB2 transformation. The FASEB Journal 24 (10) , pp. 3796-3808. 10.1096/fj.10-157347

Cabodi, Sara, Di Stefano, Paola, Leal, Maria del Pilar Camacho, Tinnirello, Agata, Bisaro, Brigitte, Morello, Virginia, Damiano, Laura, Aramu, Simona, Repetto, Daniele, Tornillo, Giusy and Defilippi, Paola 2010. Integrins and signal transduction. Becchetti, Andrea and Arcangeli, Annarosa, eds. Integrins and ion channels: Molecular complexes and signaling, Vol. 674. New York, NY: Landes Bioscience and Springer Science, pp. 43-54.

This list was generated on Sun Apr 14 04:27:03 2024 BST.