Holmes, Carys, Illingworth, Charlotte H. and Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 2024. Recent advances on the impact of pro-tumourigenic dietary derived bacterial metabolites on the intestinal stem cell. eFood 5 (6) , e70023. 10.1002/efd2.70023 |
Holmes, Carys, Illingworth, Charlotte H. and Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 2024. Recent advances on the impact of protumorigenic dietary‐derived bacterial metabolites on the intestinal stem cell. eFood 5 (6) , e70023. 10.1002/efd2.70023 |
de Paula do Nascimento, Roberto, Soto Rizzato, Julia, Polezi, Gabriele, Boughanem, Hatim, Williams, Non Gwenllian, Borguini, Galhardo, Cristina Pessanha de Araujo Santiago, Manuela, Roberto Marostica Junior, Mario and Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 2024. Myrciaria jaboticaba fruit peel: Bioactive composition as determined by distinct harvest seasons and in vitro anti-cancer activity. Plants 13 (20) , 2907. 10.3390/plants13202907 |
Williams, Jason S., Higgins, Adam T. ORCID: https://orcid.org/0000-0002-2906-8151, Stott, Katie J., Thomas, Carly, Farrell, Lydia, Bonnet, Cleo, Peneva, Severena, Derrick, Anna V., Hay, Trevor, Wang, Tianqi, Morgan, Claire, Dwyer, Sarah, D'Ambrogio, Joshua, Hogan, Catherine ORCID: https://orcid.org/0000-0002-1012-0896, Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 and Dyson, Paul 2024. Enhanced bacterial cancer therapy delivering therapeutic RNA interference of c-Myc. Cell & Bioscience 14 (38) 10.1186/s13578-024-01206-8 |
Michael, D. R., Kerry-Smith, J., Webberley, T. S., Murphy, K.R., Plummer, S. F., Parry, L. ORCID: https://orcid.org/0000-0002-4467-9196 and Marchesi, J. R. ORCID: https://orcid.org/0000-0002-7994-5239 2023. Does flow culture impact upon gut-probiotic interactions: a comparison with static culture. Journal of Functional Foods 104 , 105519. 10.1016/j.jff.2023.105519 |
Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 2022. Stemming the flow toward disease: A research profile of Lee Parry. eFood 3 (6) , e46. 10.1002/efd2.46 |
Williams, Non G. and Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 2022. Balancing the scales: Do healthy lifestyle choices offset the colorectal cancer risk of unhealthy choices? eFood 3 (6) , e45. 10.1002/efd2.45 |
May, Stephanie, Greenow, Kirsty, Higgins, Adam ORCID: https://orcid.org/0000-0002-2906-8151, Derrick, Anna, Taylor, Elaine, Pan, Pan, Konstantinou, Maria, Nixon, Colin, Woolley, Thomas ORCID: https://orcid.org/0000-0001-6225-5365, Sansom, Owen, Wang, Li-Shu and Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 2022. Modification of diet to reduce the stemness and tumourigenicity of murine and human intestinal cells. Molecular Nutrition & Food Research 66 (19) , 2200234. 10.1002/mnfr.202200234 |
Stott, Katie J., Phillips, Bethan, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 and May, Stephanie 2021. Recent advancements in the exploitation of the gut microbiome in the diagnosis and treatment of colorectal cancer. Bioscience Reports 41 (7) , BSR20204113. 10.1042/BSR20204113 |
Jukes, Zoe, Freier, Anne, Glymenaki, Maria, Brown, Richard, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Want, Elizabeth, Vorkas, Panagiotis A. and Li, Jia V. 2021. Lipid profiling of mouse intestinal organoids for studying APC mutations. Bioscience Reports 41 (3) , BSR20202915. 10.1042/BSR20202915 |
Kermanizadeh, Ali, Jacobsen, Nicklas Raus, Murphy, Fiona, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Zhang, Haiyuan and Møller, Peter 2021. A review of the current state of nanomedicines for targeting and treatment of cancers - achievements and future challenges. Advanced Therapeutics 4 (2) , 2000186. 10.1002/adtp.202000186 |
May, Stephanie, Parry, Connor and Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 2020. Berry chemoprevention: do berries decrease the window of opportunity for tumourigenesis. Food Frontiers 1 (3) 10.1002/fft2.32 |
May, Stephanie, McDermott, Grace, Marchesi, Julian ORCID: https://orcid.org/0000-0002-7994-5239 and Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 2020. Impact of black raspberries on the normal and malignant Apc deficient murine gut microbiome. Journal of Berry Research 10 (1) , pp. 61-76. 10.3233/JBR-180372 |
Kannen, Vinicius, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 and Martin, Francis L. 2019. Phages enter the fight against colorectal cancer. Trends in Cancer 5 (10) , pp. 577-579. 10.1016/j.trecan.2019.08.002 |
Young, Madeleine A., May, Stephanie, Damo, Angelos, Yoon, Young So, Hur, Man-Wook, Swat, Wojiech and Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 2019. Epigenetic regulation of Dlg1, via Kaiso, alters mitotic spindle polarity and promotes intestinal tumourigenesis. Molecular Cancer Research 17 (3) , pp. 686-696. 10.1158/1541-7786.MCR-18-0280 |
Greenow, Kristy R., Zverev, Matthew, May, Stephanie, Kendrick, Howard, Williams, Geraint T. ORCID: https://orcid.org/0000-0003-3768-9940, Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916 and Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 2018. Lect2 deficiency is characterised by altered cytokine levels and promotion of intestinal tumourigenesis. Oncotarget 9 (92) , pp. 36430-36443. 10.18632/oncotarget.26335 |
May, Stephanie, Owen, Heather, Phesse, Toby J. ORCID: https://orcid.org/0000-0001-9568-4916, Greenow, Kristy R., Jones, Gareth-Rhys, Blackwood, Adam, Cook, Peter C., Towers, Christopher, Gallimore, Awen M. ORCID: https://orcid.org/0000-0001-6675-7004, Williams, Geraint T., Sturzl, Michael, Britzen-Laurent, Nathalie, Sansom, Owen J., MacDonald, Andrew S., Bird, Adrian P., Clarke, Alan R. and Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 2018. Mbd2 enables tumourigenesis within the intestine while preventing tumour-promoting inflammation. Journal of Pathology 245 (3) , pp. 270-282. 10.1002/path.5074 |
Colbeck, Emily J., Jones, Emma, Hindley, James P., Smart, Kathryn, Schulz, Ralph, Browne, Molly, Cutting, Scott, Williams, Anwen ORCID: https://orcid.org/0000-0001-6118-020X, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567, Ware, Carl F., Ager, Ann and Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 2017. Treg depletion licenses T cell-driven HEV neogenesis and promotes tumor destruction. Cancer Immunology Research 5 (11) , pp. 1005-1015. 10.1158/2326-6066.CIR-17-0131 |
Planells-Palop, Vicente, Hazazi, Ali, Feichtinger, Julia, Jezkova, Jana, Thallinger, Gerhard, Alsiwiehri, Naif O., Almutairi, Mikhlid, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Wakeman, Jane A. and McFarlane, Ramsay J. 2017. Human germ/stem cell-specific gene TEX19 influences cancer cell proliferation and cancer prognosis. Molecular Cancer 16 , 84. 10.1186/s12943-017-0653-4 |
May, Stephanie, Evans, Samantha and Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 2017. Organoids, organs-on-chips and other systems, and microbiota. Emerging Topics in Life Sciences 1 (4) , pp. 385-400. 10.1042/ETLS20170047 |
Schmidt, Nina, Irle, Inga, Ripkens, Kamilla, Lux, Vanda, Nelles, Jasmin, Johannes, Christian, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Greenow, Kirsty, Amir, Sarah, Campioni, Mara, Baldi, Alfonso, Oka, Chio, Kawaichi, Masashi, Clarke, Alan R. and Ehrmann, Michael ORCID: https://orcid.org/0000-0002-1927-260X 2016. Epigenetic silencing of serine protease HTRA1 drives polyploidy. BMC Cancer 16 , 399. 10.1186/s12885-016-2425-8 |
Zhao, Chuntao, Deng, Yaqi, Liu, Lei, Yu, Kun, Zhang, Liguo, Wang, Haibo, He, Xuelian, Wang, Jincheng, Lu, Changqing, Wu, Laiman N, Weng, Qinjie, Mao, Meng, Li, Jianrong, van Es, Johan H, Xin, Mei, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Goldman, Steven A, Clevers, Hans and Lu, Q. Richard 2016. Dual regulatory switch through interactions of Tcf7l2/Tcf4 with stage-specific partners propels oligodendroglial maturation. Nature Communications 7 , 10883. 10.1038/ncomms10883 |
Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Young, Madeleine, El Marjou, Fatima and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2015. Protocols for analyzing the role of Paneth cells in regenerating the murine intestine using conditional cre-lox mouse models. Journal of Visualized Experiments (105) , e53429. 10.3791/53429 |
Huels, David J., Ridgway, Rachel A., Radulescu, Sorina, Leushacke, Marc, Campbell, Andrew D., Biswas, Sujata, Leedham, Simon, Serra, Stefano, Chetty, Runjan, Moreaux, Guenievre, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Matthews, James, Song, Fei, Hedley, Ann, Kalna, Gabriela, Ceteci, Fatih, Reed, Karen R. ORCID: https://orcid.org/0000-0002-7467-1718, Meniel, Valerie S., Maguire, Aoife, Doyle, Brendan, Soderberg, Ola, Barker, Nick, Watson, Alastair, Larue, Lionel, Clarke, Alan R. ORCID: https://orcid.org/0000-0002-4281-426X and Sansom, Owen J. 2015. E-cadherin can limit the transforming properties of activating β‐catenin mutations. EMBO Journal 34 (18) , pp. 2321-2333. 10.15252/embj.201591739 |
Koh, D. -I., Han, D., Ryu, H., Choi, W.-I., Jeon, B. -N., Kim, M. -K., Kim, Y., Kim, J. Y., Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X, Reynolds, A. B. and Hur, M. -W. 2014. KAISO, a critical regulator of p53-mediated transcription of CDKN1A and apoptotic genes. Proceedings of the National Academy of Sciences of the United States of America 111 (42) , pp. 15078-15083. 10.1073/pnas.1318780111 |
Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Young, Madeleine, El Marjou, Fatima and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2013. Evidence for a crucial role of Paneth Cells in mediating the intestinal response to injury. Stem Cells 31 (4) , pp. 776-785. 10.1002/stem.1326 |
Jarde, Thierry, Evans, Rebecca Jane, McQuillan, Karina, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Feng, Gui Jie, Alvares, B., Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X and Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 2013. In vivo and in vitro models for the therapeutic targeting of Wnt signaling using a Tet-OΔN89β-catenin system. Oncogene 32 (7) , pp. 883-893. 10.1038/onc.2012.103 |
Meniel, Valerie, Song, Fei, Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916, Young, Madeleine, Poetz, Oliver, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Jenkins, John R., Williams, Geraint Trefor ORCID: https://orcid.org/0000-0003-3768-9940, Dunwoodie, Sally L., Watson, Alastair and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2013. Cited1 deficiency suppresses intestinal tumorigenesis. PLoS Genetics 9 (8) , e1003638. 10.1371/journal.pgen.1003638 |
Smartt, Helena J. M., Greenhough, Alexander, Ordonez-Moran, Paloma, Talero, Elena, Cherry, Catherine A., Wallam, Catherine A., Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Al Kharusi, Manal Al, Roberts, Heather R., Mariadason, John M., Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X, Huelsken, Joerg, Williams, Ann C. and Paraskeva, Chris 2012. β-catenin represses expression of the tumour suppressor 15-prostaglandin dehydrogenase in the normal intestinal epithelium and colorectal tumour cells. Gut 61 (9) , pp. 1306-1314. 10.1136/gutjnl-2011-300817 |
Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2011. The roles of the methyl-CpG binding proteins in cancer. Genes & Cancer 2 (6) , pp. 618-630. 10.1177/1947601911418499 |
Cole, Alicia, Ridgway, Rachel, Derkits, Sahra, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Barker, Nick, Clevers, Hans, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X and Sansom, Owen 2010. p21 loss blocks senescence following Apc loss and provokes tumourigenesis in the renal but not the intestinal epithelium. EMBO Molecular Medicine 2 (11) , pp. 472-486. 10.1002/emmm.201000101 |
Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Ewan, Kenneth Burnside Ramsay ORCID: https://orcid.org/0000-0001-6622-9009, Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963, Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010 and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2008. Deficiency of Mbd2 attenuates Wnt induced tumourigenesis via deregulation of a novel Wnt inhibitor, Lect.2. Molecular and Cellular Biology 28 (19) , pp. 6094-6103. 10.1128/MCB.00539-08 |
Wilson, Catherine Helen, Idziaszczyk, Shelley Alexis, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Guy, Carol, Griffiths, David Francis Rees, Lazda, Edgar Janis, Bayne, Rosemary A. L., Smith, Andrew J. H., Sampson, Julian Roy ORCID: https://orcid.org/0000-0002-2902-2348 and Cheadle, Jeremy Peter ORCID: https://orcid.org/0000-0001-9453-8458 2005. A mouse model of tuberous sclerosis 1 showing background specific early post-natal mortality and metastatic renal cell carcinoma. Human Molecular Genetics 14 (13) , pp. 1839-1850. 10.1093/hmg/ddi190 |
Kirby, Denise M., Salemi, Renato, Sugiana, Canny, Ohtake, Akira, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Bell, Katrina M., Kirk, Edwin P., Boneh, Avihu, Taylor, Robert W., Dahl, Hans-Henrik M., Ryan, Michael T. and Thorburn, David R. 2004. NDUFS6 mutations are a novel cause of lethal neonatal mitochondrial complex I deficiency. The Journal of Clinical Investigation 114 (6) , pp. 837-845. 10.1172/JCI200420683 |
Dixon, P. F., Avery, S., Chambers, E., Feist, S., Mandhar, H., Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Stone, D. M., Stremmen, H. K., Thurlow, J. K., Lui, C. Tsin-yee and Way, K. 2003. Four years of monitoring for viral haemorrhagic septicaemia virus in marine waters around the United Kingdom. Disease of Aquatic Organisms 54 (3) , pp. 175-186. 10.3354/dao054175 |
Hodges, Angela K., Li, Shaowei, Maynard, Julie Helen, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Braverman, Richard, DeClue, Jeffrey E., Cheadle, Jeremy Peter ORCID: https://orcid.org/0000-0001-9453-8458 and Sampson, Julian Roy ORCID: https://orcid.org/0000-0002-2902-2348 2001. Pathological mutations in TSC1 and TSC2 disrupt the interaction between hamartin and tuberin. Human Molecular Genetics 10 (25) , pp. 2899-9205. 10.1093/hmg/10.25.2899 |
Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Maynard, Julie Helen, Patel, A., Clifford, S. C., Morrissey, C., Maher, E. R., Cheadle, Jeremy Peter ORCID: https://orcid.org/0000-0001-9453-8458 and Sampson, Julian Roy ORCID: https://orcid.org/0000-0002-2902-2348 2001. Analysis of the TSC1 and TSC2 genes in sporadic renal cell carcinomas. British Journal of Cancer 85 , pp. 1226-1230. 10.1054/bjoc.2001.2072 |
Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Maynard, Julie Helen, Patel, Amit, Hodges, Angela, von Deimling, Andreas, Sampson, Julian Roy ORCID: https://orcid.org/0000-0002-2902-2348 and Cheadle, Jeremy Peter ORCID: https://orcid.org/0000-0001-9453-8458 2000. Molecular analysis of the TSC1 and TSC2 tumour suppressor genes in sporadic glial and glioneuronal tumours. Human Genetics 107 (4) , pp. 350-356. 10.1007/s004390000390 |
Dixon, P.F., Feist, S., Kehoe, E., Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Stone, D.M. and Way, K. 1997. Isolation of viral haemorrhagic septicaemia virus from Atlantic herring Clupea harengus from the Atlantic herring Clupea harengus from the English channel. Diseases of Aquatic Organisms 30 (2) , pp. 81-89. |
Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 and Dixon, P. F. 1997. Stability of nine viral haemorrhagic septicaemia virus (VHSV) isolates in seawater. Bulletin of the European Association of Fish Pathologists 17 (1) , pp. 31-36. |