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Number of items: 27.

Maddison, Robert, Reed, Karen R. ORCID: https://orcid.org/0000-0002-7467-1718, Cannings-John, Rebecca ORCID: https://orcid.org/0000-0001-5235-6517, Lugg-Widger, Fiona ORCID: https://orcid.org/0000-0003-0029-9703, Stoneman, Thomas, Anderson, Sarah and Fry, Andrew E. ORCID: https://orcid.org/0000-0001-9778-6924 2025. Adapting historical clinical genetic test records for anonymised data linkage: obstacles and opportunities. International Journal of Population Data Science 8 (5) , pp. 1-6. 10.23889/ijpds.v8i5.2924
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Queiroz, Cleberson J.S., Song, Fei, Reed, Karen R. ORCID: https://orcid.org/0000-0002-7467-1718, Al-Khafaji, Nadeem, Clarke, Alan R. ORCID: https://orcid.org/0000-0002-4281-426X, Vimalachandran, Dale, Miyajima, Fabio, Pritchard, D. Mark and Jenkins, John R. 2020. NAP1L1: a novel human colorectal cancer biomarker derived from animal models of Apc inactivation. Frontiers in Oncology 10 , 1565. 10.3389/fonc.2020.01565
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Mohamed, Noha-Ehssan, Hay, Trevor, Reed, Karen R. ORCID: https://orcid.org/0000-0002-7467-1718, Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 and Clarke, Alan R. ORCID: https://orcid.org/0000-0002-4281-426X 2019. APC2 is critical for ovarian WNT signalling control, fertility and tumour suppression. BMC Cancer 19 , 677. 10.1186/s12885-019-5867-y
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Young, Madeleine, Daly, Carl, Taylor, Elaine, James, Rhiannon, Clarke, Alan and Reed, Karen ORCID: https://orcid.org/0000-0002-7467-1718 2018. Subtle deregulation of the Wnt-signalling pathway through loss of Apc2 reduces the fitness of intestinal stem cells. Stem Cells 36 (1) , pp. 114-122. 10.1002/stem.2712
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Burke, Zoë D., Reed, Karen R. ORCID: https://orcid.org/0000-0002-7467-1718, Yeh, Sheng-Wen, Meniel, Valerie, Sansom, Owen J., Clarke, Alan R. and Tosh, David 2018. Spatiotemporal regulation of liver development by the Wnt/β-catenin pathway. Scientific Reports 8 (1) 10.1038/s41598-018-20888-y
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Burke, Zoe D., Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Yeh, Sheng-Wen, Meniel, Valerie S., Sansom, Owen J., Clarke, Alan R. and Tosh, David 2018. Spatiotemporal regulation of liver development by the Wnt/β- catenin pathway. Scientific Reports 8 , 2735. 10.1038/s41598-018-20888-y
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Daly, C. S., Shaw, Paul ORCID: https://orcid.org/0000-0002-7467-0619, Ordonez, L. D., Williams, G. T., Quist, J., Grigoriadis, A., Van Es, J. H., Clevers, H., Clarke, Alan Richard and Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718 2017. Functional redundancy between Apc and Apc2 regulates tissue homeostasis and prevents tumorigenesis in murine mammary epithelium. Oncogene 36 (13) 10.1038/onc.2016.342
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Young, Madeleine and Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718 2016. Organoids as a model for colorectal cancer. Current Colorectal Cancer Reports 12 (5) , pp. 281-287. 10.1007/s11888-016-0335-4
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Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Song, Fei, Young, Madeleine, Hassan, N., Antoine, A. J., Gemici, Nesibe-Princess B, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X and Jenkins, J. R. 2016. Secreted HMGB1 from Wnt activated intestinal cells is required to maintain a crypt progenitor phenotype. Oncotarget 7 (32) , pp. 51665-51673. 10.18632/oncotarget.10076
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Huels, David J., Ridgway, Rachel A., Radulescu, Sorina, Leushacke, Marc, Campbell, Andrew D., Biswas, Sujata, Leedham, Simon, Serra, Stefano, Chetty, Runjan, Moreaux, Guenievre, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Matthews, James, Song, Fei, Hedley, Ann, Kalna, Gabriela, Ceteci, Fatih, Reed, Karen R. ORCID: https://orcid.org/0000-0002-7467-1718, Meniel, Valerie S., Maguire, Aoife, Doyle, Brendan, Soderberg, Ola, Barker, Nick, Watson, Alastair, Larue, Lionel, Clarke, Alan R. ORCID: https://orcid.org/0000-0002-4281-426X and Sansom, Owen J. 2015. E-cadherin can limit the transforming properties of activating β‐catenin mutations. EMBO Journal 34 (18) , pp. 2321-2333. 10.15252/embj.201591739
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Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Athineos, Dimitris, Meniel, Valerie, Wilkins, Julie A., Ridgway, Rachel A., Burke, Zoe D., Muncan, Vanessa, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X and Sansom, Owen J. 2015. Correction for Reed et al., B-catenin deficiency, but not Myc deletion, suppresses the immediate phenotypes of APC loss in the liver. Proceedings of the National Academy of Sciences of the United States of America 112 (10) , E1168. 10.1073/pnas.1502294112

Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Korobko, Igor, Ninkina, Natalia ORCID: https://orcid.org/0000-0001-8570-5648, Korobko, Elena V., Hopkins, Ben R., Platt, James L., Buchman, Vladimir ORCID: https://orcid.org/0000-0002-7631-8352 and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2015. Hunk/Mak-v is a negative regulator of intestinal cell proliferation. BMC Cancer 15 , 110. 10.1186/s12885-015-1087-2
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Hammoudi, Abeer, Song, Fei, Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Jenkins, Rosalind E., Meniel, Valerie, Watson, Alastair J. M., Pritchard, D. Mark, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X and Jenkins, John R. 2013. Proteomic profiling of a mouse model of acute intestinal Apc deletion leads to identification of potential novel biomarkers of human colorectal cancer (CRC). Biochemical and Biophysical Research Communications 440 (3) , pp. 364-370. 10.1016/j.bbrc.2013.08.076

Feng, Gui Jie, Cotta, Welwyn, Wei, Xiao-Qing ORCID: https://orcid.org/0000-0002-6274-8503, Poetz, Oliver, Evans, Rebecca Jane, Jardé, Thierry, Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Meniel, Valerie, Williams, Geraint Trefor ORCID: https://orcid.org/0000-0003-3768-9940, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X and Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 2012. Conditional disruption of Axin1 leads to development of liver tumors in mice. Gastroenterology 143 (6) , pp. 1650-1659. 10.1053/j.gastro.2012.08.047

Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Tunster, Simon James ORCID: https://orcid.org/0000-0002-2242-9452, Young, Madeleine, Carrico, Adam Stephen, John, Rosalind Margaret ORCID: https://orcid.org/0000-0002-3827-7617 and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2012. Entopic overexpression of Ascl2 does not accelerate tumourigenesis in ApcMin mice. Gut 61 (10) , pp. 1435-1438. 10.1136/gutjnl-2011-300842

Kant, P., Sainsbury, A., Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Pollard, S. G., Scott, N., Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X, Coletta, P. L. and Hull, M. A. 2011. Rectal epithelial cell mitosis and expression of macrophage migration inhibitory factor are increased 3 years after Roux-en-Y gastric bypass (RYGB) for morbid obesity: implications for long-term neoplastic risk following RYGB. Gut 60 (7) , pp. 893-901. 10.1136/gut.2010.230755

Cole, Alicia M., Myant, Kevin, Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Ridgway, Rachel A., Athineos, Dimitris, Van den Brink, Gijs, Muncan, Vanesa, Clevers, Hans, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X, Sicinski, Peter and Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010 2010. Cyclin D2-cyclin-dependent kinase 4/6 is required for efficient proliferation and tumorigenesis following Apc loss. Cancer Research 70 (20) , pp. 8149-8158. 10.1158/0008-5472.CAN-10-0315

Burke, Zoé D., Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916, Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X and Tosh, David 2009. Liver zonation occurs through a β-catenin–dependent, c-Myc–independent mechanism. Gastroenterology 136 (7) , pp. 2316-2324. 10.1053/j.gastro.2009.02.063

Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Athineos, Dimitris, Meniel, Valerie, Wilkins, Julie Ann, Ridgeway, Rachel A., Burke, Zoe D., Muncan, Vanesa, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X and Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010 2008. B-catenin deficiency, but not Myc deletion, suppresses the immediate phenotypes of APC loss in the liver. Proceedings of the National Academy of Sciences of the United States of America 105 (48) , pp. 18919-18923. 10.1073/pnas.0805778105

Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Meniel, Valerie, Marsh Durban, Victoria ORCID: https://orcid.org/0000-0003-1645-1618, Cole, Alicia, Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010 and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2008. A limited role for p53 in modulating the immediate phenotype of Apc loss in the intestine. BMC Cancer 8 , 162. 10.1186/1471-2407-8-162
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Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Ewan, Kenneth Burnside Ramsay ORCID: https://orcid.org/0000-0001-6622-9009, Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963, Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010 and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2008. Deficiency of Mbd2 attenuates Wnt induced tumourigenesis via deregulation of a novel Wnt inhibitor, Lect.2. Molecular and Cellular Biology 28 (19) , pp. 6094-6103. 10.1128/MCB.00539-08

Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010, Meniel, Valerie, Muncan, Vanesa, Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916, Wilkins, Julie Ann, Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Vass, Keith, Athineos, Dimitris, Clevers, Hans and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2007. Myc deletion rescues Apc deficiency in the small intestine. Nature 446 (7136) , pp. 676-679. 10.1038/nature05674

Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010, Hayes, Anthony Joseph, Gescher, Andreas J., Peters, Jefferey M. and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2006. PPARδ status and mismatch repair mediated neoplasia in the mouse intestine. BMC Cancer 6 (113) 10.1186/1471-2407-6-113
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Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010, Griffiths, David Francis Rees, Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Winton, Douglas J. and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2005. Apc deficiency predisposes to renal carcinoma in the mouse. Oncogene 24 , pp. 8205-8210. 10.1038/sj.onc.1208956

Sansom, Owen J., Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, van de Wetering, M., Muncan, V., Winton, D. J., Clevers, H. and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2005. Cyclin D1 is not an immediate target of β-Catenin following Apc loss in the intestine. Journal of Biological Chemistry 280 (31) , pp. 28463-28467. 10.1074/jbc.M500191200

Sansom, Owen J., Reed, Karen ORCID: https://orcid.org/0000-0002-7467-1718, Hayes, Anthony Joseph, Ireland, Heather, Brinkmann, Hannah, Newton, Ian P., Batlle, Edouard, Simon-Assmann, Patricia, Clevers, Hans, Nathke, Inke S, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X and Winton, Douglas J. 2004. Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration. Genes and Development 18 (12) , pp. 1385-1390. 10.1101/gad.287404
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Reed, Karen Ruth ORCID: https://orcid.org/0000-0002-7467-1718, Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010, Hayes, Anthony Joseph, Gescher, Andreas J., Winton, Douglas J., Peters, Jeffrey M. and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2004. PPARδ status and Apc-mediated tumourigenesis in the mouse intestine. Oncogene 23 (55) , pp. 8992-8996. 10.1038/sj.onc.1208143

This list was generated on Mon Mar 31 05:54:02 2025 BST.


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