Browse by All Cardiff Authors

Wren, Georgina, Flanagan, Jessica, Underwood, Jack ORCID: https://orcid.org/0000-0003-1731-6039, Thompson, Andrew ORCID: https://orcid.org/0000-0001-6788-7222, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799 and Davies, William ORCID: https://orcid.org/0000-0002-7714-2440 2024. Memory, mood and associated neuroanatomy in individuals with steroid sulfatase deficiency (X-linked ichthyosis). Genes, Brain and Behavior 23 (3) , e12893. 10.1111/gbb.12893

Bosworth, Matthew L. ORCID: https://orcid.org/0000-0003-1391-7515, Isles, Anthony R. ORCID: https://orcid.org/0000-0002-7587-5712, Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124 and Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799 2024. Sex-dependent effects of Setd1a haploinsufficiency on development and adult behaviour. PLoS ONE 10.1371/journal.pone.0298717

Wren, Georgina, Baker, Emily, Underwood, Jack ORCID: https://orcid.org/0000-0003-1731-6039, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Thompson, Andrew ORCID: https://orcid.org/0000-0001-6788-7222, Kirov, George ORCID: https://orcid.org/0000-0002-3427-3950, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 and Davies, William ORCID: https://orcid.org/0000-0002-7714-2440 2023. Characterising heart rhythm abnormalities associated with Xp22.31 deletion. Journal of Medical Genetics 60 , pp. 636-643. 10.1136/jmg-2022-108862

Wren, Georgina, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Thompson, Andrew ORCID: https://orcid.org/0000-0001-6788-7222 and Davies, William ORCID: https://orcid.org/0000-0002-7714-2440 2022. Mood symptoms, neurodevelopmental traits, and their contributory factors in X-linked ichthyosis, ichthyosis vulgaris and psoriasis. Clinical and Experimental Dermatology 47 (6) , pp. 1097-1108. 10.1111/ced.15116

Pass, Rachel ORCID: https://orcid.org/0000-0002-3652-0126, Haan, Niels, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124, Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009 and Thomas, Kerrie L. ORCID: https://orcid.org/0000-0003-3355-9583 2022. Selective behavioural impairments in mice heterozygous for the cross disorder psychiatric risk gene DLG2. Genes, Brain and Behavior 21 (4) , e12799. 10.1111/gbb.12799

Waldron, Sophie, Pass, Rachel ORCID: https://orcid.org/0000-0002-3652-0126, Griesius, Simonas, Mellor, Jack R., Robinson, Emma S. J., Thomas, Kerrie L. ORCID: https://orcid.org/0000-0003-3355-9583, Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009 and Dwyer, Dominic M. ORCID: https://orcid.org/0000-0001-8069-5508 2022. Behavioural and molecular characterisation of the Dlg2 haploinsufficiency rat model of genetic risk for psychiatric disorder. Genes, Brain and Behavior 21 (4) , e12797. 10.1111/gbb.12797

Westacott, Laura J., Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Haan, Niels, Brain, Sophie A., Bush, Emma-Louise, Toneva, Margarita, Baloc, Andreea-Ingrid, Moon, Anna L. ORCID: https://orcid.org/0000-0002-6587-4425, Reddaway, Jack, Owen, Michael J. ORCID: https://orcid.org/0000-0003-4798-0862, Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009, Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Gray, William P. ORCID: https://orcid.org/0000-0001-7595-8887 and Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124 2022. Complement C3 and C3aR mediate different aspects of emotional behaviours; relevance to risk for psychiatric disorder. Brain, Behavior, and Immunity 99 , pp. 70-82. 10.1016/j.bbi.2021.09.005

Westacott, Laura J., Haan, Niels, Evison, Claudia, Marei, Omar, Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009, Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490, Zaben, Malik ORCID: https://orcid.org/0000-0002-7446-4532, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124 and Gray, William P. ORCID: https://orcid.org/0000-0001-7595-8887 2021. Dissociable effects of complement C3 and C3aR on survival and morphology of adult born hippocampal neurons, pattern separation, and cognitive flexibility in male mice. Brain, Behavior, and Immunity 98 , pp. 136-150. 10.1016/j.bbi.2021.08.215

Zahova, Simona, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Davies, Jennifer, Morgan, Joanne E. and Isles, Anthony ORCID: https://orcid.org/0000-0002-7587-5712 2021. Comparison of mouse models reveals a molecular distinction between psychotic illness in PWS and schizophrenia. Translational Psychiatry 11 , 433. 10.1038/s41398-021-01561-x

Dent, Claire L., Rienecker, Kira D. A., Ward, Andrew, Wilkins, Jon F, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799 and Isles, Anthony R. ORCID: https://orcid.org/0000-0002-7587-5712 2020. Mice lacking paternal expression of imprinted 1 Grb10 are risk-takers. Genes, Brain and Behavior 19 (7) , e12679. 10.1111/gbb.12679

Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Smith, Georgia E., Small, Rebecca, Davies, William ORCID: https://orcid.org/0000-0002-7714-2440, Carter, Jenny, Bentley, Chloe A., Winstanley, Catharine A., Rogers, Robert D. and Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124 2020. Effects of 5-HT2C, 5-HT1A receptor challenges and modafinil on the initiation and persistence of gambling behaviours. Psychopharmacology 237 , pp. 1745-1756. 10.1007/s00213-020-05496-x

Sykes, Lucy, Haddon, Josephine ORCID: https://orcid.org/0000-0001-5975-813X, Lancaster, Thomas M. ORCID: https://orcid.org/0000-0003-1322-2449, Sykes, Arabella, Azzouni, Karima, Niklas, Ihssen, Moon, Anna L. ORCID: https://orcid.org/0000-0002-6587-4425, Lin, Tzu-Ching E., Linden, David E. ORCID: https://orcid.org/0000-0002-5638-9292, Owen, Michael J. ORCID: https://orcid.org/0000-0003-4798-0862, O'Donovan, Michael C. ORCID: https://orcid.org/0000-0001-7073-2379, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124, Thomas, Kerrie L. ORCID: https://orcid.org/0000-0003-3355-9583 and Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009 2019. Genetic variation in the psychiatric risk gene CACNA1C modulates reversal learning across species. Schizophrenia Bulletin 45 (5) , pp. 1024-1032. 10.1093/schbul/sby146

Davies, Jennifer R. ORCID: https://orcid.org/0000-0001-7415-6129, Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124, Isles, Anthony R. ORCID: https://orcid.org/0000-0002-7587-5712 and Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799 2019. Prader-Willi syndrome imprinting centre deletion mice have impaired baseline and 5-HT2CR-mediated response inhibition. Human Molecular Genetics 28 (18) , pp. 3013-3023. 10.1093/hmg/ddz100

Silva, Ana I., Haddon, Josephine E., Syed, Yasir Ahmed ORCID: https://orcid.org/0000-0001-9495-307X, Trent, Simon ORCID: https://orcid.org/0000-0001-9563-4281, Tzu-Ching, E. Lin, Patel, Yateen, Carter, Jenny, Haan, Niels, Honey, Robert C. ORCID: https://orcid.org/0000-0001-6870-1880, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Assaf, Yaniv, Owen, Michael J. ORCID: https://orcid.org/0000-0003-4798-0862, Linden, David E. J. ORCID: https://orcid.org/0000-0002-5638-9292, Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009 and Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124 2019. Cyfip1 haploinsufficient rats show white matter changes, myelin thinning, abnormal oligodendrocytes and behavioural inflexibility. Nature Communications 10 , 3455. 10.1038/s41467-019-11119-7

Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Patel, Yateen, Carter, Jenny, Stokes, Laura-Jean G., Rogers, Robert D. and Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124 2019. Feeding behaviour, risk-sensitivity and response control: effects of 5-HT 2C receptor manipulations. Philosophical Transactions B: Biological Sciences 374 (1766) , 20180144. 10.1098/rstb.2018.0144

Isles, Anthony R. ORCID: https://orcid.org/0000-0002-7587-5712, Winstanley, Catharine A. and Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799 2019. Risk taking and impulsive behaviour: fundamental discoveries, theoretical perspectives and clinical implications. Philosophical Transactions B: Biological Sciences 374 (1766) , -. 10.1098/rstb.2018.0128

Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799 and Davies, William ORCID: https://orcid.org/0000-0002-7714-2440 2019. Brain gene expression in a novel mouse model of postpartum mood disorder. Translational Neuroscience 10 (1) , pp. 168-174. 10.1515/tnsci-2019-0030

Dent, Claire L., Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Lewis, Katie, Ward, Andrew, Fischer-Colbrie, Reiner, Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124, Wilkins, Jon F. and Isles, Anthony R. ORCID: https://orcid.org/0000-0002-7587-5712 2018. Impulsive choice in mice lacking paternal expression of Grb10 suggests intragenomic conflict in behavior. Genetics 209 (1) , pp. 233-239. 10.1534/genetics.118.300898

McNamara, G. I., Davis, B. A., Browne, M., Humby, T. ORCID: https://orcid.org/0000-0002-1840-1799, Dalley, J. W., Xia, J., John, R. M. ORCID: https://orcid.org/0000-0002-3827-7617 and Isles, A. R. ORCID: https://orcid.org/0000-0002-7587-5712 2018. Dopaminergic and behavioral changes in a loss-of-imprinting model of Cdkn1c. Genes, Brain and Behavior 17 (2) , pp. 149-157. 10.1111/gbb.12422

Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Fisher, Amelia, Allen, Christopher, Reynolds, Meghann, Hartman, Annette, Giegling, Ina, Rujescu, Dan and Davies, William ORCID: https://orcid.org/0000-0002-7714-2440 2017. A genetic variant within STS previously associated with inattention in boys with Attention Deficit Hyperactivity Disorder is associated with enhanced cognition in healthy adult males. Brain and Behavior 7 (3) , e00646. 10.1002/brb3.646

Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Cross, Ellen S., Messer, Lauren, Guerrero, Silvia and Davies, William ORCID: https://orcid.org/0000-0002-7714-2440 2016. A pharmacological mouse model suggests a novel risk pathway for postpartum psychosis. Psychoneuroendocrinology 74 , pp. 363-370. 10.1016/j.psyneuen.2016.09.019

Dent, Claire, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Swaden Lewis, Katie J., Plagge, A, Fischer-Colbrie, R, Wilkins, J. F., Wilkinson, Lawrence ORCID: https://orcid.org/0000-0002-9337-6124 and Isles, Anthony Roger ORCID: https://orcid.org/0000-0002-7587-5712 2016. Impulsive choices in mice lacking imprinted Nesp55. Genes, Brain and Behavior 15 (8) , pp. 693-701. 10.1111/gbb.12316

Chatterjee, Sohini, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799 and Davies, William ORCID: https://orcid.org/0000-0002-7714-2440 2016. Behavioural and psychiatric phenotypes in men and boys with X-linked ichthyosis: evidence from a worldwide online survey. PLoS ONE 11 (10) , e0164417. 10.1371/journal.pone.0164417

Davies, Jennifer R. ORCID: https://orcid.org/0000-0001-7415-6129, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Dwyer, Dominic M. ORCID: https://orcid.org/0000-0001-8069-5508, Garfield, Alastair S., Furby, Hannah ORCID: https://orcid.org/0000-0002-7279-1812, Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124, Wells, Timothy ORCID: https://orcid.org/0000-0003-3618-0595 and Isles, Anthony Roger ORCID: https://orcid.org/0000-0002-7587-5712 2015. Calorie seeking, but not hedonic response, contributes to hyperphagia in a mouse model for Prader-Willi syndrome. European Journal of Neuroscience 42 (4) , pp. 2105-2113. 10.1111/ejn.12972

Davies, William ORCID: https://orcid.org/0000-0002-7714-2440, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Trent, Simon ORCID: https://orcid.org/0000-0001-9563-4281, Eddy, Jessica B., Ojarikre, Obah A. and Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124 2014. Genetic and pharmacological modulation of the steroid sulfatase axis improves response control; comparison to drugs used in ADHD. Neuropsychopharmacology 39 , pp. 2622-2632. 10.1038/npp.2014.115

Hiscox, Lucy ORCID: https://orcid.org/0000-0001-6296-7442, Leonaviciute, Erika and Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799 2014. The effects of automatic spelling correction software on understanding and comprehension in compensated dyslexia: improved recall following dictation. Dyslexia 20 (3) , pp. 208-224. 10.1002/dys.1480

Dent, Claire, Isles, Anthony Roger ORCID: https://orcid.org/0000-0002-7587-5712 and Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799 2014. Measuring risk-taking in mice: balancing the risk between seeking reward and danger. European Journal of Neuroscience 39 (4) , pp. 520-530. 10.1111/ejn.12430

Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Eddy, Jessica B., Good, Mark Andrew ORCID: https://orcid.org/0000-0002-1824-1203, Reichelt, Amy C. and Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 2013. A novel translational assay of response inhibition and impulsivity: effects of prefrontal cortex lesions, drugs used in ADHD, and serotonin 2C receptor antagonism. Neuropsychopharmacology 38 (11) , pp. 2150-2159. 10.1038/npp.2013.112

Reichelt, Amy C., Killcross, Simon, Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799 and Good, Mark Andrew ORCID: https://orcid.org/0000-0002-1824-1203 2013. Transgenic expression of the FTDP-17 tauV337M mutation in brain dissociates components of executive function in mice. Neurobiology of Learning and Memory 104 , pp. 73-81. 10.1016/j.nlm.2013.05.005

Kopsida, Eleni, Lynn, Phoebe M., Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 and Davies, William ORCID: https://orcid.org/0000-0002-7714-2440 2013. Dissociable effects of sry and sex chromosome complement on activity, feeding and anxiety-related behaviours in mice. PLoS ONE 8 (8) , e73699. 10.1371/journal.pone.0073699

Trent, Simon ORCID: https://orcid.org/0000-0001-9563-4281, Dean, Rachel, Veit, Bonnie, Cassano, Tommaso, Bedse, Gaurav, Ojarikre, Obah A., Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799 and Davies, William ORCID: https://orcid.org/0000-0002-7714-2440 2013. Biological mechanisms associated with increased perseveration and hyperactivity in a genetic mouse model of neurodevelopmental disorder. Psychoneuroendocrinology 38 (8) , pp. 1370-1380. 10.1016/j.psyneuen.2012.12.002

Mikaelsson, Mikael Allan, Constância, Miguel, Dent, Claire, Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 and Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799 2013. Placental programming of anxiety in adulthood revealed by lgf2-null models. Nature Communications 4 , 2311. 10.1038/ncomms3311

Relkovic, Dinko, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Hagan, Jim J., Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 and Isles, Anthony Roger ORCID: https://orcid.org/0000-0002-7587-5712 2012. Enhanced appetitive learning and reversal learning in a mouse model for Prader-Willi syndrome. Behavioral Neuroscience 126 (3) , pp. 488-492. 10.1037/a0028155

Trent, Simon ORCID: https://orcid.org/0000-0001-9563-4281, Cassano, Tommaso, Bedse, Gaurav, Ojarikre, Obah A, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799 and Davies, William ORCID: https://orcid.org/0000-0002-7714-2440 2012. Altered serotonergic function may partially account for behavioral endophenotypes in steroid sulfatase-deficient mice. Neuropsychopharmacology 37 (5) , pp. 1267-1274. 10.1038/npp.2011.314

Trent, Simon ORCID: https://orcid.org/0000-0001-9563-4281, Dennehy, Alison, Richardson, Heather, Ojarikre, Obah A., Burgoyne, Paul S., Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799 and Davies, William ORCID: https://orcid.org/0000-0002-7714-2440 2012. Steroid sulfatase-deficient mice exhibit endophenotypes relevant to Attention Deficit Hyperactivity Disorder. Psychoneuroendocrinology 37 (2) , pp. 221-229. 10.1016/j.psyneuen.2011.06.006

Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799 and Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 2011. Assaying dissociable elements of behavioural inhibition and impulsivity: translational utility of animal models. Current Opinion in Pharmacology 11 (5) , pp. 534-539. 10.1016/j.coph.2011.06.006

Relkovic, Dinko, Doe, Christine M., Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Johnstone, Karen A., Resnick, James L., Holland, Anthony J., Hagan, Jim J., Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 and Isles, Anthony Roger ORCID: https://orcid.org/0000-0002-7587-5712 2010. Behavioural and cognitive abnormalities in an imprinting centre deletion mouse model for Prader–Willi syndrome. European Journal of Neuroscience 31 (1) , pp. 156-164. 10.1111/j.1460-9568.2009.07048.x

Davies, William ORCID: https://orcid.org/0000-0002-7714-2440, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Kong, Wendy, Otter, Tamara Leonie, Burgoyne, Paul S. and Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 2009. Converging pharmacological and genetic evidence indicates a role for steroid sulfatase in attention. Biological Psychiatry 66 (4) , pp. 360-367. 10.1016/j.biopsych.2009.01.001

Doe, Christine M., Relkovic, Dinko, Garfield, Alastair S., Dalley, J. W., Theobald, D. E.H., Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 and Isles, Anthony Roger ORCID: https://orcid.org/0000-0002-7587-5712 2009. Loss of the imprinted snoRNA mbii-52 leads to increased 5htr2c pre-RNA editing and altered 5HT2CR-mediated behaviour. Human Molecular Genetics 18 (12) , pp. 2140-2148. 10.1093/hmg/ddp137

Doe, C., Garfield, A., Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Relkovic, D., Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 and Isles, Anthony Roger ORCID: https://orcid.org/0000-0002-7587-5712 2008. 5-HT2CR pre-RNA editing, alternate splicing and function in a mouse model of Prader-Willi syndrome. Fundamental & Clinical Pharmacology 22 (s2) , p. 125. 10.1111/j.1472-8206.2008.00601.x

Donald, S., Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Fyfe, I., Segonds-Pichon, A., Walker, S. A., Andrews, S. R., Coadwell, W. J., Emson, P., Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 and Welch, H. C. E. 2008. P-Rex2 regulates Purkinje cell dendrite morphology and motor coordination. Proceedings of the National Academy of Sciences of the United States of America 105 (11) , pp. 4483-4488. 10.1073/pnas.0712324105

Davies, William ORCID: https://orcid.org/0000-0002-7714-2440, Isles, Anthony Roger ORCID: https://orcid.org/0000-0002-7587-5712, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799 and Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 2008. What are imprinted genes doing in the brain? Wilkins, Jon F., ed. Genomic Imprinting, Advances in experimental medicine and biology, vol. 626. Berlin: Springer, pp. 62-70. (10.1007/978-0-387-77576-0_5)

Lambourne, Sarah L., Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Isles, Anthony Roger ORCID: https://orcid.org/0000-0002-7587-5712, Emson, Piers C., Spillantini, Maria G. and Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 2007. Impairments in impulse control in animal models transgenic for the human FTPD-17 tauV337M mutation are exacerbated by age. Human Molecular Genetics 16 (14) , pp. 1708-1719. 10.1093/hmg/ddm119

Davies, William ORCID: https://orcid.org/0000-0002-7714-2440, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Isles, Anthony Roger ORCID: https://orcid.org/0000-0002-7587-5712, Burgoyne, Paul S. and Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 2007. X-monosomy effects on visuospatial attention in mice: a candidate gene and implications for Turner syndrome and attention deficit hyperactivity disorder. Biological psychiatry 61 (12) , pp. 1351-1360. 10.1016/j.biopsych.2006.08.011

Davies, William ORCID: https://orcid.org/0000-0002-7714-2440, Isles, Anthony Roger ORCID: https://orcid.org/0000-0002-7587-5712, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799 and Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 2007. What are imprinted genes doing in the brain? [Review]. Epigenetics 2 (4) , pp. 201-206. 10.4161/epi.2.4.5379

Colebrooke, Rebecca E., Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Lynch, Patrick J., McGowan, Daniel P., Xia, Jing and Emson, Piers C. 2006. Age-related decline in striatal dopamine content and motor performance occurs in the absence of nigral cell loss in a genetic mouse model of Parkinson's disease. European Journal of Neuroscience 24 (9) , pp. 2622-2630. 10.1111/j.1460-9568.2006.05143.x

Tofaris, George K., Reitbock, Pablo Gracia, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Lambourne, Sarah L., O'Connell, Mark, Ghetti, Bernadino, Gossage, Helen, Emson, Piers C., Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124, Goedert, Michel and Spillantini, Maria Grazia 2006. Pathological changes in dopaminergic nerve cells of the substantia nigra and olfactory bulb in mice transgenic for truncated human alpha-synuclein(1-120): implications for Lewy body disorders. Journal of Neuroscience 26 (15) , pp. 3942-3950. 10.1523/JNEUROSCI.4965-05.2006

Isles, Anthony Roger ORCID: https://orcid.org/0000-0002-7587-5712 and Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799 2006. Modes of imprinted gene action in learning disability. Journal of Intellectual Disability Research 50 (5) , pp. 318-325. 10.1111/j.1365-2788.2006.00843.x

Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799 and Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 2006. If only they could talk - genetic mouse models for psychiatric disorders. Fish, G. S. and Flint, J., eds. Transgenic and Knockout Models of Neuropsychiatric Disorders, Contemporary Clinical Neuroscience, Totowa, NJ: Humana Press, pp. 69-83. (10.1007/978-1-59745-058-4_4)

Isles, Anthony Roger ORCID: https://orcid.org/0000-0002-7587-5712, Hathway, Gareth J., Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, de la Riva, Carlos, Kendrick, Keith M. and Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 2005. An mTph2 SNP gives rise to alterations in extracellular 5-HT levels, but not in performance on a delayed-reinforcement task. European Journal of Neuroscience 22 (4) , pp. 997-1000. 10.1111/j.1460-9568.2005.04265.x

Davies, William ORCID: https://orcid.org/0000-0002-7714-2440, Isles, Anthony Roger ORCID: https://orcid.org/0000-0002-7587-5712, Smith, Rachel, Karunadasa, Delicia, Burrmann, Doreen, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Ojarikre, Obah, Biggin, Carol, Skuse, David, Burgoyne, Paul S. and Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 2005. Xlr3b is a new imprinted candidate for X-linked parent-of-origin effects on cognitive function in mice. Nature Genetics 37 (6) , pp. 625-629. 10.1038/ng1577

Plagge, Antonius, Isles, Anthony Roger ORCID: https://orcid.org/0000-0002-7587-5712, Gordon, Emma, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Dean, Wendy, Gritsch, Sabine, Fischer-Colbrie, Reiner, Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 and Kelsey, Gavin 2005. Imprinted Nesp55 influences behavioral reactivity to novel environments. Molecular and Cellular Biology 25 (8) , pp. 3019-3026. 10.1128/MCB.25.8.3019-3026.2005

Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 and Dawson, Gerry 2005. UNIT 8.5H assaying aspects of attention and impulse control in mice using the 5-choice serial reaction time task. Current Protocols in Neuroscience, Chichester: Wiley, (10.1002/0471142301.ns0805hs31)

Isles, Anthony Roger ORCID: https://orcid.org/0000-0002-7587-5712, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Walters, Eurof and Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 2004. Common genetic effects on variation in impulsivity and activity in mice. Journal of Neuroscience 24 (30) , pp. 6733-6740. 10.1523/JNEUROSCI.1650-04.2004

Isles, Anthony Roger ORCID: https://orcid.org/0000-0002-7587-5712, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799 and Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 2003. Measuring impulsivity in mice using a novel operant delayed reinforcement task: effects of behavioural manipulations and d-amphetamine. Psychopharmacology 170 (4) , pp. 376-382. 10.1007/s00213-003-1551-6

Davies, W., Isles, Anthony Roger ORCID: https://orcid.org/0000-0002-7587-5712, Burgoyne, P. S., Ward, B. O., Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, de la Riva, C. and Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 2003. Evidence for X-linked imprinted gene functioning on cognition in mice; a possible neurochemical basis, and implications for cognitive sexual dimorphism [Abstract]. Journal of Psychopharmacology 17 (S) , A70.

Mooslehner, K. A., Chan, P. M., Xu, W. M., Liu, L. Z., Smadja, C., Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Allen, Nicholas Denby ORCID: https://orcid.org/0000-0003-4009-186X, Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 and Emson, P. C. 2001. Mice with Very Low Expression of the Vesicular Monoamine Transporter 2 Gene Survive into Adulthood: Potential Mouse Model for Parkinsonism. Molecular and Cellular Biology 21 (16) , pp. 5321-5331. 10.1128/MCB.21.16.5321-5331.2001

Caine, S. B., Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Robbins, T. W. and Everitt, B. J. 2001. Behavioral effects of psychomotor stimulants in rats with dorsal or ventral subiculum lesions: Locomotion, cocaine self-administration, and prepulse inhibition of startle. Behavioral Neuroscience 115 (4) , pp. 880-894. 10.1037/0735-7044.115.4.880

Baunez, C., Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Eagle, D. M., Ryan, L. J., Dunnett, Stephen Bruce ORCID: https://orcid.org/0000-0003-1826-1578 and Robbins, T. W. 2001. Effects of STN lesions on simple vs choice reaction time tasks in the rat: preserved motor readiness, but impaired response selection. European Journal of Neuroscience 13 (8) , pp. 1609-1616. 10.1046/j.0953-816x.2001.01521.x

Passetti, F., Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Everitt, B. J. and Robbins, T. W. 2000. Mixed attentional and executive deficits in medial frontal cortex lesioned rats. Psychobiology 28 (2) , pp. 261-271.

Eagle, D. M., Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Dunnett, Stephen Bruce ORCID: https://orcid.org/0000-0003-1826-1578 and Robbins, T. W. 1999. Effects of regional striatal lesions on motor, motivational, and executive aspects of progressive-ratio performance in rats. Behavioral Neuroscience 113 (4) , pp. 718-731. 10.1037/0735-7044.113.4.718

Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Laird, Fiona M., Davies, William ORCID: https://orcid.org/0000-0002-7714-2440 and Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 1999. Visuospatial attentional functioning in mice: interactions between cholinergic manipulations and genotype. European Journal of Neuroscience 11 (8) , pp. 2813-2823. 10.1046/j.1460-9568.1999.00701.x

Eagle, D. M., Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Howman, M., Reid-Henry, A., Dunnett, Stephen Bruce ORCID: https://orcid.org/0000-0003-1826-1578 and Robbins, T. W. 1999. Differential effects of ventral and regional dorsal striatal lesions on sucrose drinking and positive and negative contrast in rats. Psychobiology 27 (2) , pp. 267-276.

Hall, F. S., Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799 and Robbins, T. W. 1999. Maternal deprivation of neonatal rats produces enduring changes in dopamine function. Synapse 32 (1) , pp. 37-43. 10.1002/(SICI)1098-2396(199904)32:1<37::AID-SYN5>3.0.CO;2-4

Carter, R. J., Lione, L. A., Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Mangiarini, L., Mahal, A., Bates, G. P., Dunnett, Stephen Bruce ORCID: https://orcid.org/0000-0003-1826-1578 and Morton, A. J. 1999. Characterization of progressive motor deficits in mice transgenic for the human Huntington's disease mutation. The Journal of Neuroscience 19 (8) , pp. 3248-3257.

French, S. J., Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Horner, C. H., Sofroniew, M. V. and Rattray, M. 1999. Hippocampal neurotrophin and trk receptor mRNA levels are altered by local administration of nicotine, carbachol and pilocarpine. Molecular Brain Research 67 (1) , pp. 124-136. 10.1016/S0169-328X(99)00048-0

Hall, F. S., Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Inglis, W., Kendall, D. A., Marsden, C. A. and Robbins, T. W. 1998. Isolation rearing in rats: Pre- and postsynaptic changes in striatal dopaminergic systems. Pharmacology, Biochemistry and Behavior 59 (4) , pp. 859-872. 10.1016/S0091-3057(97)00510-8

Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Killcross, Andrew Simon, Torres, EM, Everitt, B. J. and Robbins, T. W. 1998. Dissociations in dopamine release in medial prefrontal cortex and ventral striatum during the acquisition and extinction of classical aversive conditioning in the rat. European Journal of Neuroscience 10 (3) , pp. 1019-1026. 10.1046/j.1460-9568.1998.00119.x

Eagle, D. M., Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Robbins, T. W. and Dunnett, Stephen Bruce ORCID: https://orcid.org/0000-0003-1826-1578 1998. A progressive ratio study of response to reward following striatal damage [Abstract]. European Journal of Neuroscience 10 (S) , p. 418.

French, S. J., Rattray, M., Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799 and Sofronlew, M.V. 1998. Regulation of hippocampal neurotrophin gene expression by sub-toxic and behaviourally inactive doses of glutamatergic and cholinergic agonists [Abstract]. European Journal of Neuroscience 10 (S) , p. 116.

Brasted, P. J., Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Dunnett, Stephen Bruce ORCID: https://orcid.org/0000-0003-1826-1578 and Robbins, T. W. 1997. Unilateral lesions of the dorsal striatum in rats disrupt responding in egocentric space. The Journal of Neuroscience 17 (22) , pp. 8919-8926.

Hall, F. S., Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 and Robbins, T. W. 1997. The effects of isolation-rearing on preference by rats for a novel environment. Physiology & Behavior 62 (2) , pp. 299-303. 10.1016/S0031-9384(97)00117-0

Hall, F. S., Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 and Robbins, T. W. 1997. The effects of isolation-rearing on sucrose consumption in rats. Physiology & Behavior 62 (2) , pp. 291-297. 10.1016/S0031-9384(97)00116-9

Hall, F. S., Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 and Robbins, T. W. 1997. The effects of isolation-rearing of rats on behavioural responses to food and environmental novelty. Physiology & Behavior 62 (2) , pp. 281-290. 10.1016/S0031-9384(97)00115-7

Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Robbins, T. W. and Everitt, B. J. 1995. Differential Effects of Forebrain 5-Hydroxytryptamine Depletions on Pavlovian Aversive Conditioning to Discrete and Contextual Stimuli in the Rat. European Journal of Neuroscience 7 (10) , pp. 2042-2052. 10.1111/j.1460-9568.1995.tb00627.x

Geyer, M. A., Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799 and Robbins, T. W. 1995. Prepulse inhibition of startle-induced reductions of accumbens dopamine [Abstract]. Biological Psychiatry 37 (9) , p. 634. 10.1016/0006-3223(95)94560-J