Browse by Current Cardiff authors

Wills, Christopher, Watts, Katie, Houseman, Amy, Maughan, Timothy S., Fisher, David, Al-Tassan, Nada A., Houlston, Richard S., Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 and Cheadle, Jeremy ORCID: https://orcid.org/0000-0001-9453-8458 2025. Relationship between inherited genetic variation and survival from colorectal cancer stratified by tumour location. Scientific Reports 15 , 2423. 10.1038/s41598-024-77870-0

Graham, Andrew, Bellou, Eftychia, Harwood, Janet, Yaman, Urman, Celikag, Meral, Magusali, Naciye, Rambarack, Naiomi, Botia, Juan, Frigerio, Carlo Sala, Hardy, John, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 and Salih, Dervis 2025. Human longevity and Alzheimer’s disease variants act via microglia and oligodendrocyte gene networks. Brain , awae339. 10.1093/brain/awae339

Bellou, Eftychia, Kim, Woori, Leonenko, Ganna ORCID: https://orcid.org/0000-0001-8025-661X, Tao, Feifei, Simmonds, Emily, Wu, Ying, Mattsson-Carlgren, Niklas, Hansson, Oskar, Nagle, Michael W. and Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 2025. Benchmarking Alzheimer's disease prediction: personalised risk assessment using polygenic risk scores across various methodologies and genome-wide studies. Alzheimer's Research and Therapy 17 (1) , 6. 10.1186/s13195-024-01664-9

Chandler, Hannah Louise, Wheeler, Joshua, Escott‐Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Murphy, Kevin ORCID: https://orcid.org/0000-0002-6516-313X and Lancaster, Thomas Matthew ORCID: https://orcid.org/0000-0003-1322-2449 2024. Non‐APOE variants predominately expressed in smooth muscle cells contribute to the influence of Alzheimer's disease genetic risk on white matter hyperintensities. Alzheimer's & Dementia: The Journal of the Alzheimer's Association 10.1002/alz.14455

Hou, Jiahui, Hess, Jonathan L., Zhang, Chunling, van Rooij, Jeroen G. J., Hearn, Gentry C., Fan, Chun Chieh, Faraone, Stephen V., Fennema‐Notestine, Christine, Lin, Shu‐Ju, Escott‐Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Seshadri, Sudha, Holmans, Peter ORCID: https://orcid.org/0000-0003-0870-9412, Tsuang, Ming T., Kremen, William S., Gaiteri, Chris and Glatt, Stephen J. 2024. Meta‐analysis of transcriptomic studies of blood and six brain regions identifies a consensus of 15 cross‐tissue mechanisms in Alzheimer's disease and suggests an origin of cross‐study heterogeneity. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 10.1002/ajmg.b.33019

Ibanez, Kristina, Jadhav, Bharati, Zanovello, Matteo, Gagliardi, Delia, Clarkson, Christopher, Facchini, Stefano, Garg, Paras, Martin-Trujillo, Alejandro, Gies, Scott, Galassi Deforie, Valentina, Dalmia, Anupriya, Hensman Moss, Davina J, Vandrovcova, Jana, Rocca, Clarissa, Moutsianas, Loukas, Marini-Bettolo, Chiara, Walker, Helen, Turner, Chris, Shoai, Maryam, Long, Jeffrey, EUROSCA network, Fratta, Pietro, Langbehn, Douglas, Tabrizi, Sarah, Caulfield, Mark, Cortese, Andrea, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, hardy, John, Houlden, Henry, Sharp, Andrew and Tucci, Arianna 2024. Increased frequency of repeat expansion mutations across different populations. Nature Medicine 30 , pp. 3357-3368. 10.1038/s41591-024-03190-5

Woolway, Grace E., Legge, Sophie E., Lynham, Amy J., Smart, Sophie E. ORCID: https://orcid.org/0000-0002-6709-5425, Hubbard, Leon, Daniel, Ellie R., Pardiñas, Antonio F. ORCID: https://orcid.org/0000-0001-6845-7590, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, O’Donovan, Michael C., Owen, Michael J. ORCID: https://orcid.org/0000-0003-4798-0862, Jones, Ian R. and Walters, James T. R. ORCID: https://orcid.org/0000-0002-6980-4053 2024. Assessing the validity of a self-reported clinical diagnosis of schizophrenia. Schizophrenia 10 (1) , 99. 10.1038/s41537-024-00526-5

Simmonds, Emily, Leonenko, Ganna ORCID: https://orcid.org/0000-0001-8025-661X, Yaman, Umran, Bellou, Eftychia, Myers, Amanda, Morgan, Kevin, Brookes, Keeley, Hardy, John, Salih, Dervis and Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 2024. Chromosome X-wide association study in case control studies of pathologically confirmed Alzheimer’s disease in a European population. Translational Psychiatry 14 (1) , 358. 10.1038/s41398-024-03058-9

Shitomi-Jones, Lisa M., Dolman, Clare, Jones, Ian ORCID: https://orcid.org/0000-0001-5821-5889, Kirov, George ORCID: https://orcid.org/0000-0002-3427-3950, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Legge, Sophie E. and Di Florio, Arianna ORCID: https://orcid.org/0000-0003-0338-2748 2024. Exploration of first onsets of mania, schizophrenia spectrum disorders and major depressive disorder in perimenopause. nature mental health 2 (10) , pp. 1161-1168. 10.1038/s44220-024-00292-4

Zhao, Yibo, Bracher-Smith, Matthew, Li, Yuelin, Harvey, Kirsten, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Lewis, Patrick A. and Manzoni, Claudia 2024. Transcriptomics and weighted protein network analyses of the LRRK2 protein interactome reveal distinct molecular signatures for sporadic and LRRK2 Parkinson’s Disease. npj Parkinson's Disease 10 (1) , 144. 10.1038/s41531-024-00761-8

Legge, Sophie E., Pardinas, Antonio F. ORCID: https://orcid.org/0000-0001-6845-7590, Woolway, Grace, Rees, Elliott ORCID: https://orcid.org/0000-0002-6168-9222, Cardno, Alastair G., Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Holmans, Peter ORCID: https://orcid.org/0000-0003-0870-9412, Kirov, George ORCID: https://orcid.org/0000-0002-3427-3950, Owen, Michael ORCID: https://orcid.org/0000-0003-4798-0862, O'Donovan, Michael J. ORCID: https://orcid.org/0000-0001-7073-2379 and Walters, James T. R. ORCID: https://orcid.org/0000-0002-6980-4053 2024. Genetic and phenotypic features of Schizophrenia in the UK Biobank. JAMA Psychiatry 81 , pp. 681-690. 10.1001/jamapsychiatry.2024.0200

Manzoni, Claudia, Kia, Demis A., Ferrari, Raffaele, Leonenko, Ganna ORCID: https://orcid.org/0000-0001-8025-661X, Costa, Beatrice, Saba, Valentina, Jabbari, Edwin, Tan, Manuela M. X., Albani, Diego, Alvarez, Victoria, Alvarez, Ignacio, Andreassen, Ole A., Angiolillo, Antonella, Arighi, Andrea, Baker, Matt, Benussi, Luisa, Bessi, Valentina, Binetti, Giuliano, Blackburn, Daniel J., Boada, Merce, Boeve, Bradley F., Borrego-Ecija, Sergi, Borroni, Barbara, Bråthen, Geir, Brooks, William S., Bruni, Amalia C., Caroppo, Paola, Bandres-Ciga, Sara, Clarimon, Jordi, Colao, Rosanna, Cruchaga, Carlos, Danek, Adrian, de Boer, Sterre CM., de Rojas, Itziar, di Costanzo, Alfonso, Dickson, Dennis W., Diehl-Schmid, Janine, Dobson-Stone, Carol, Dols-Icardo, Oriol, Donizetti, Aldo, Dopper, Elise, Durante, Elisabetta, Ferrari, Camilla, Forloni, Gianluigi, Frangipane, Francesca, Fratiglioni, Laura, Kramberger, Milica G., Galimberti, Daniela, Gallucci, Maurizio, García-González, Pablo, Ghidoni, Roberta, Giaccone, Giorgio, Graff, Caroline, Graff-Radford, Neill R., Grafman, Jordan, Halliday, Glenda M., Hernandez, Dena G., Hjermind, Lena E., Hodges, John R., Holloway, Guy, Huey, Edward D., Illán-Gala, Ignacio, Josephs, Keith A., Knopman, David S., Kristiansen, Mark, Kwok, John B., Leber, Isabelle, Leonard, Hampton L., Libri, Ilenia, Lleo, Alberto, Mackenzie, Ian R., Madhan, Gaganjit K., Maletta, Raffaele, Marquié, Marta, Maver, Ales, Menendez-Gonzalez, Manuel, Milan, Graziella, Miller, Bruce L., Morris, Christopher M., Morris, Huw R., Nacmias, Benedetta, Newton, Judith, Nielsen, Jørgen E., Nilsson, Christer, Novelli, Valeria, Padovani, Alessandro, Pal, Suvankar, Pasquier, Florence, Pastor, Pau, Perneczky, Robert, Peterlin, Borut, Petersen, Ronald C., Piguet, Olivier, Pijnenburg, Yolande AL., Puca, Annibale A., Rademakers, Rosa, Rainero, Innocenzo, Reus, Lianne M., Richardson, Anna MT., Riemenschneider, Matthias, Rogaeva, Ekaterina, Rogelj, Boris, Rollinson, Sara, Rosen, Howard, Rossi, Giacomina, Rowe, James B., Rubino, Elisa, Ruiz, Agustin, Salvi, Erika, Sanchez-Valle, Raquel, Sando, Sigrid Botne, Santillo, Alexander F., Saxon, Jennifer A., Schlachetzki, Johannes CM., Scholz, Sonja W., Seelaar, Harro, Seeley, William W., Serpente, Maria, Sorbi, Sandro, Sordon, Sabrina, St George-Hyslop, Peter, Thompson, Jennifer C., Van Broeckhoven, Christine, Van Deerlin, Vivianna M., Van der Lee, Sven J., Van Swieten, John, Tagliavini, Fabrizio, van der Zee, Julie, Veronesi, Arianna, Vitale, Emilia, Waldo, Maria Landqvist, Yokoyama, Jennifer S., Nalls, Mike A., Momeni, Parastoo, Singleton, Andrew B., Hardy, John and Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 2024. Genome-wide analyses reveal a potential role for the MAPT, MOBP, and APOE loci in sporadic frontotemporal dementia. American Journal of Human Genetics 111 (7) , pp. 1316-1329. 10.1016/j.ajhg.2024.05.017

Trastulla, Lucia, Dolgalev, Georgii, Moser, Sylvain, Jiménez-Barrón, Laura, Andlauer, Till, von Scheidt, Moritz, Schizophrenia Working Group of the Psychiatric Genomics Consorti, Budde, Monika, Heilbronner, Urs, Papiol, Sergei, Teumer, Alexander, Homouth, Georg, Falkai, Peter, Volzke, Henry, Dorr, Marcus, Schulze, Thomas, Gagneur, Julien, Iorio, Francesco, Müller-Myhsok, Bertram, Schunkert, Heribert, Ziller, Michael, O'Donovan, Michael ORCID: https://orcid.org/0000-0001-7073-2379, Carrera, Noa ORCID: https://orcid.org/0000-0003-0739-0382, Craddock, Nicholas ORCID: https://orcid.org/0000-0003-2171-0610, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Georgieva, Lyudmila, Hamshere, Marian L. ORCID: https://orcid.org/0000-0002-8990-0958, Kavanagh, David, Kirov, George ORCID: https://orcid.org/0000-0002-3427-3950, Legge, Sophie, Owen, Michael J. ORCID: https://orcid.org/0000-0003-4798-0862, Pocklington, Andrew ORCID: https://orcid.org/0000-0002-2137-0452, Richards, Alexander L., Walters, James T. R. ORCID: https://orcid.org/0000-0002-6980-4053, Williams, Nigel M. ORCID: https://orcid.org/0000-0003-1177-6931 and Holmans, Peter A. ORCID: https://orcid.org/0000-0003-0870-9412 2024. Distinct genetic liability profiles define clinically relevant patient strata across common diseases. Nature Communications 15 , 5534. 10.1038/s41467-024-49338-2

Stevenson-Hoare, Joshua, Legge, Sophie E., Simmonds, Emily, Han, Jun, Owen, Michael J. ORCID: https://orcid.org/0000-0003-4798-0862, O'Donovan, Michael ORCID: https://orcid.org/0000-0001-7073-2379, Kirov, George ORCID: https://orcid.org/0000-0002-3427-3950 and Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 2024. Severe psychiatric disorders are associated with increased risk of dementia. BMJ Mental Health 27 (1) , e301097. 10.1136/bmjment-2024-301097

Leonenko, Ganna ORCID: https://orcid.org/0000-0001-8025-661X, Bauermeister, Sarah, Ghanti, Dipanwita, Stevenson-Hoare, Joshua, Simmonds, Emily, Brookes, Keeley, Morgan, Kevin, Chaturvedi, Nishi, Elliot, Paul, Sudlow, Cathie, Thomas, Alan, Wareham, Nicholas, Gallacher, John and Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 2024. Dementias Platform UK: Bringing genetics into life. Alzheimer's & Dementia: The Journal of the Alzheimer's Association 20 (5) , pp. 3281-3289. 10.1002/alz.13782

Caseras, Xavier ORCID: https://orcid.org/0000-0002-8490-6891, Simmonds, Emily, Pardiñas, Antonio F. ORCID: https://orcid.org/0000-0001-6845-7590, Anney, Richard ORCID: https://orcid.org/0000-0002-6083-407X, Legge, Sophie E., Walters, James T. R. ORCID: https://orcid.org/0000-0002-6980-4053, Harrison, Neil A. ORCID: https://orcid.org/0000-0002-9584-3769, O’Donovan, Michael C. and Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 2024. Common risk alleles for schizophrenia within the major histocompatibility complex predict white matter microstructure. Translational Psychiatry 14 , 194. 10.1038/s41398-024-02910-2

Martin Flores, Nuria, Podpolny, Marina, McLeod, Faye, Workman, Isaac, Crawford, Karen, Ivanov, Dobril ORCID: https://orcid.org/0000-0001-6271-6301, Leonenko, Ganna ORCID: https://orcid.org/0000-0001-8025-661X, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 and Salinas, Patricia C 2024. Downregulation of Dickkopf-3, a Wnt antagonist elevated in Alzheimer’s disease, restores synapse integrity and memory in a disease mouse model. eLife 12 , RP89453. 10.7554/elife.89453

O'Connell, Kevin, Koromina, Maria, van der Veen, Tracey, Boltz, Toni, David, Friederike, O'Donovan, Michael ORCID: https://orcid.org/0000-0001-7073-2379, Walters, James ORCID: https://orcid.org/0000-0002-6980-4053, Owen, Michael ORCID: https://orcid.org/0000-0003-4798-0862, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Pardinas, Antonio ORCID: https://orcid.org/0000-0001-6845-7590, Holmans, Peter ORCID: https://orcid.org/0000-0003-0870-9412 and Jones, Ian ORCID: https://orcid.org/0000-0001-5821-5889 2024. Genomics yields biological and phenotypic insights into bipolar disorder. Biological Psychiatry Item availability restricted.

Steventon, Jessica J., Lancaster, Thomas M., Simmonds Baker, Emily, Bracher-Smith, Matthew, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Ruth, Katherine S., Davies, William ORCID: https://orcid.org/0000-0002-7714-2440, Caseras, Xavier ORCID: https://orcid.org/0000-0002-8490-6891 and Murphy, Kevin ORCID: https://orcid.org/0000-0002-6516-313X 2023. Menopause age, reproductive span and hormone therapy duration predict the volume of medial temporal lobe brain structures in postmenopausal women. Psychoneuroendocrinology 158 , 106393. 10.1016/j.psyneuen.2023.106393

Lancaster, Thomas ORCID: https://orcid.org/0000-0003-1322-2449, Creese, Byron, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Driver, Ian ORCID: https://orcid.org/0000-0001-6815-0134, Menzies, Georgina ORCID: https://orcid.org/0000-0002-6600-6507, Khan, Zunera, Corbett, Anne, Ballard, Clive, Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259, Murphy, Kevin ORCID: https://orcid.org/0000-0002-6516-313X and Chandler, Hannah 2023. Proof-of-concept recall-by-genotype study of extremely low and high Alzheimer’s polygenic risk reveals autobiographical deficits and cingulate cortex correlates. Alzheimer's Research and Therapy 15 , 213. 10.1186/s13195-023-01362-y

Caseras, Xavier ORCID: https://orcid.org/0000-0002-8490-6891, Legge, Sophie, Bracher-Smith, Matthew, Anney, Richard ORCID: https://orcid.org/0000-0002-6083-407X, Owen, Michael ORCID: https://orcid.org/0000-0003-4798-0862, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 and Kirov, George ORCID: https://orcid.org/0000-0002-3427-3950 2023. Copy Number Variants increasing risk for schizophrenia: shared and distinct effects on brain morphometry and cognitive performance. Biological Psychiatry: Global Open Science 3 (4) , pp. 902-911. 10.1016/j.bpsgos.2022.10.006

Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 and Schmidt, Karl Michael ORCID: https://orcid.org/0000-0002-0227-3024 2023. Pitfalls of predicting age related traits by polygenic risk scores. Annals of Human Genetics 87 (5) , pp. 203-209. 10.1111/ahg.12520

Harrison, Judith R. ORCID: https://orcid.org/0000-0002-5775-2524, Foley, Sonya F. ORCID: https://orcid.org/0000-0002-8390-2709, Baker, Emily, Bracher-Smith, Matthew, Holmans, Peter ORCID: https://orcid.org/0000-0003-0870-9412, Stergiakouli, Evie, Linden, David E.J. ORCID: https://orcid.org/0000-0002-5638-9292, Caseras, Xavier ORCID: https://orcid.org/0000-0002-8490-6891, Jones, Derek K. ORCID: https://orcid.org/0000-0003-4409-8049 and Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 2023. Pathway-specific polygenic scores for Alzheimer's disease are associated with changes in brain structure in younger and older adults. Brain Communications 5 (5) , fcad229. 10.1093/braincomms/fcad229

Le Guen, Yann, Luo, Guo, Ambati, Aditya, Damotte, Vincent, Jansen, Iris, Yu, Eric, Nicolas, Aude, de Rojas, Itziar, Peixoto Leal, Thiago, Miyashita, Akinori, Bellenguez, Céline, Lian, Michelle Mulan, Parveen, Kayenat, Morizono, Takashi, Park, Hyeonseul, Grenier-Boley, Benjamin, Naito, Tatsuhiko, Küçükali, Fahri, Talyansky, Seth D., Yogeshwar, Selina Maria, Sempere, Vicente, Satake, Wataru, Alvarez, Victoria, Arosio, Beatrice, Belloy, Michael E., Benussi, Luisa, Boland, Anne, Borroni, Barbara, Bullido, María J., Caffarra, Paolo, Clarimon, Jordi, Daniele, Antonio, Darling, Daniel, Debette, Stéphanie, Deleuze, Jean-François, Dichgans, Martin, Dufouil, Carole, During, Emmanuel, Düzel, Emrah, Galimberti, Daniela, Garcia-Ribas, Guillermo, García-Alberca, José María, García-González, Pablo, Giedraitis, Vilmantas, Goldhardt, Oliver, Graff, Caroline, Grünblatt, Edna, Hanon, Olivier, Hausner, Lucrezia, Heilmann-Heimbach, Stefanie, Holstege, Henne, Hort, Jakub, Jung, Yoo Jin, Jürgen, Deckert, Kern, Silke, Kuulasmaa, Teemu, Lee, Kun Ho, Lin, Ling, Masullo, Carlo, Mecocci, Patrizia, Mehrabian, Shima, de Mendonça, Alexandre, Boada, Mercè, Mir, Pablo, Moebus, Susanne, Moreno, Fermin, Nacmias, Benedetta, Nicolas, Gael, Niida, Shumpei, Nordestgaard, Børge G., Papenberg, Goran, Papma, Janne, Parnetti, Lucilla, Pasquier, Florence, Pastor, Pau, Peters, Oliver, Pijnenburg, Yolande A. L., Piñol-Ripoll, Gerard, Popp, Julius, Porcel, Laura Molina, Puerta, Raquel, Pérez-Tur, Jordi, Rainero, Innocenzo, Ramakers, Inez, Real, Luis M., Riedel-Heller, Steffi, Rodriguez-Rodriguez, Eloy, Ross, Owen A., Luís Royo, Jose, Rujescu, Dan, Scarmeas, Nikolaos, Scheltens, Philip, Scherbaum, Norbert, Schneider, Anja, Seripa, Davide, Skoog, Ingmar, Solfrizzi, Vincenzo, Spalletta, Gianfranco, Squassina, Alessio, van Swieten, John, Sánchez-Valle, Raquel, Tan, Eng-King, Tegos, Thomas, Teunissen, Charlotte, Thomassen, Jesper Qvist, Tremolizzo, Lucio, Vyhnalek, Martin, Verhey, Frans, Waern, Margda, Wiltfang, Jens, Zhang, Jing, Zetterberg, Henrik, Blennow, Kaj, He, Zihuai, Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259, Amouyel, Philippe, Jessen, Frank, Kehoe, Patrick G., Andreassen, Ole A., Van Duin, Cornelia, Tsolaki, Magda, Sánchez-Juan, Pascual, Frikke-Schmidt, Ruth, Sleegers, Kristel, Toda, Tatsushi, Zettergren, Anna, Ingelsson, Martin, Okada, Yukinori, Rossi, Giacomina, Hiltunen, Mikko, Gim, Jungsoo, Ozaki, Kouichi, Sims, Rebecca ORCID: https://orcid.org/0000-0002-3885-1199, Foo, Jia Nee, van der Flier, Wiesje, Ikeuchi, Takeshi, Ramirez, Alfredo, Mata, Ignacio, Ruiz, Agustín, Gan-Or, Ziv, Lambert, Jean-Charles, Greicius, Michael D., Mignot, Emmanuel, Bellenguez, Céline, Küçükali, Fahri, Jansen, Iris, Andrade, Victor, Moreno-Grau, Sonia, Amin, Najaf, Grenier-Boley, Benjamin, Campos-Martin, Rafael, Holmans, Peter A., Boland, Anne, Kleineidam, Luca, Damotte, Vincent, van der Lee, Sven J., Kuulasmaa, Teemu, de Rojas, Itziar, Yaqub, Amber, Prokic, Ivana, Costa, Marcos R, Chapuis, Julien, Ahmad, Shahzad, Giedraitis, Vilmantas, Aarsland, Dag, Garcia-Gonzalez, Pablo, Abdelnour, Carla, Alarcón-Martín, Emilio, Alcolea, Daniel, Alegret, Montserrat, Alvarez, Ignacio, Álvarez, Victoria, Armstrong, Nicola J., Anthoula, Tsolaki, Appollonio, Ildebrando, Arcaro, Marina, Archetti, Silvana, Arias Pastor, Alfonso, Arosio, Beatrice, Athanasiu, Lavinia, Bailly, Henri, Banaj, Nerisa, Baquero, Miquel, Belén Pastor, Ana, Benussi, Luisa, Berr, Claudine, Besse, Céline, Bessi, Valentina, Binetti, Giuliano, Bizarro, Alessandra, Blesa, Rafael, Boada, Mercè, Borroni, Barbara, Boschi, Silvia, Bossù, Paola, Bråthen, Geir, Bresner, Catherine, Brodaty, Henry, Brookes, Keeley J., Ignacio Brusco, Luis, Buiza-Rueda, Dolores, BÛrger, Katharina, Burholt, Vanessa, Calero, Miguel, Chene, Geneviève, Carracedo, Ángel, Cecchetti, Roberta, Cervera-Carles, Laura, Charbonnier, Camille, Chillotti, Caterina, Ciccone, Simona, Claassen, Jurgen A.H.R., Clarimon, Jordi, Clark, Christopher, Conti, Elisa, Corma-Gómez, Anaïs, Costantini, Emanuele, Custodero, Carlo, Daian, Delphine, Dalmasso, Maria Carolina, Daniele, Antonio, Dardiotis, Efthimios, Dartigues, Jean-François, de Deyn, Peter Paul, Debette, Stéphanie, Deckert, Jürgen, del Ser, Teodoro, Denning, Nicola, Dichgans, Martin, Diehl-Schmid, Janine, Diez-Fairen, Mónica, Dionigi Rossi, Paolo, Djurovic, Srdjan, Duron, Emmanuelle, Düzel, Emrah, Dufouil, Carole, Escott-Price, Valentina, Espinosa, Ana, Ewers, Michael, Fernández-Fuertes, Marta, Ferreira, Catarina B, Ferri, Evelyn, Fin, Bertrand, Fischer, Peter, Fladby, Tormod, Fließbach, Klaus, Fortea, Juan, Fostinelli, Silvia, Fox, Nick C., Franco-Macías, Emlio, Bullido, María J., Frank-García, Ana, Froelich, Lutz, Galimberti, Daniela, Maria García-Alberca, Jose, García-González, Pablo, Garcia-Madrona, Sebastian, Garcia-Ribas, Guillermo, Ghidoni, Roberta, Giegling, Ina, Giorgio, Giaccone, Goldhardt, Oliver, González-Pérez, Antonio, Graff, Caroline, Grande, Giulia, Green, Emma, Grimmer, Timo, Grünblatt, Edna, Guetta-Baranes, Tamar, Haapasalo, Annakaisa, Hadjigeorgiou, Georgios, Hampel, Harald, Hanon, Olivier, Hardy, John, Hartmann, Annette M., Hausner, Lucrezia, Harwood, Janet, Heilmann-Heimbach, Stefanie, Helisalmi, Seppo, Heneka, Michael T., Hernández, Isabel, Herrmann, Martin J., Hoffmann, Per, Holmes, Clive, Holstege, Henne, Huerto Vilas, Raquel, Hulsman, Marc, Johansson, Charlotte, Kilander, Lena, Kinhult Ståhlbom, Anne, Kivipelto, Miia, Koivisto, Anne, Kornhuber, Johannes, Kosmidis, Mary H., Lage, Carmen, Laukka, Erika J, Lauria, Alessandra, Lehtisalo, Jenni, Lerch, Ondrej, Lleó, Alberto, de Munain, Adolfo Lopez, Löwemark, Malin, Luckcuck, Lauren, Macías, Juan, MacLeod, Catherine A., Maier, Wolfgang, Mangialasche, Francesca, Marco, Spallazzi, Marquié, Marta, Marshall, Rachel, Martín Montes, Angel, Martínez Rodríguez, Carmen, Masullo, Carlo, Mead, Simon, Mecocci, Patrizia, Medina, Miguel, Meggy, Alun, Mehrabian, Shima, Mendoza, Silvia, Menéndez-González, Manuel, Mir, Pablo, Moebus, Susanne, Mol, Merel, Molina-Porcel, Laura, Montrreal, Laura, Morelli, Laura, Moreno, Fermin, Morgan, Kevin, Möthen, Markus M, Muchnik, Carolina, Nacmias, Benedetta, Ngandu, Tiia, Nicolas, Gael, Nordestgaard, Børge G., Olaso, Robert, Orellana, Adelina, Orsini, Michela, Ortega, Gemma, Padovani, Alessandro, Paolo, Caffarra, Papenberg, Goran, Parnetti, Lucilla, 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Wills, Christopher, Houseman, Amy, Watts, Katie, Maughan, Timothy S., Fisher, David, Houlston, Richard S., West, Hannah D. ORCID: https://orcid.org/0000-0002-6104-6534, Escott Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 and Cheadle, Jeremy P. ORCID: https://orcid.org/0000-0001-9453-8458 2023. Relationship between 233 colorectal cancer risk loci and survival in 1,926 patients with advanced disease. BJC Reports 1 , 2. 10.1038/s44276-023-00003-z

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Donnelly, Nicholas, Cunningham, Adam, Salas, Sergio Marco, Bracher-Smith, Matthew, Chawner, Samuel, Stochl, Jan, Ford, Tamsin, Raymond, F. Lucy, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 and van den Bree, Marianne B. M. ORCID: https://orcid.org/0000-0002-4426-3254 2023. Identifying the neurodevelopmental and psychiatric signatures of genomic disorders associated with intellectual disability: a machine learning approach. Molecular Autism 14 (1) , 19. 10.1186/s13229-023-00549-2

Stevenson-Hoare, Joshua, Leonenko, Ganna ORCID: https://orcid.org/0000-0001-8025-661X and Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 2023. Comparison of long-term effects of metformin on longevity between people with type 2 diabetes and matched non-diabetic controls. BMC Public Health 23 , 804. 10.1186/s12889-023-15764-y

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Stevenson-Hoare, Joshua, Heslegrave, Amanda, Leonenko, Ganna ORCID: https://orcid.org/0000-0001-8025-661X, Fathalla, Dina, Bellou, Eftychia, Luckcuck, Lauren, Marshall, Rachel, Sims, Rebecca ORCID: https://orcid.org/0000-0002-3885-1199, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Hardy, John, de Strooper, Bart, Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259, Zetterberg, Henrik and Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 2023. Plasma biomarkers and genetics in the diagnosis and prediction of Alzheimer's disease. Brain 146 (2) , pp. 690-699. 10.1093/brain/awac128

Zhao, Yibo, Vavouraki, Nikoleta, Lovering, Ruth, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Harvey, Kirsten, Lewis, Patrick and Manzoni, Claudia 2023. Tissue specific LRRK2 interactomes reveal a distinct striatal functional unit. PLoS Computational Biology 19 (1) , e1010847. 10.1371/journal.pcbi.1010847

Petrican, Raluca ORCID: https://orcid.org/0000-0002-1363-5553, Paine, Amy L. ORCID: https://orcid.org/0000-0002-9025-3719, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 and Shelton, Katherine H. ORCID: https://orcid.org/0000-0002-1311-5291 2023. Overlapping brain correlates of superior cognition among children at genetic risk for Alzheimer’s disease and/or major depressive disorder. Scientific Reports 13 (1) , p. 984. 10.1038/s41598-023-28057-6

Bellou, Eftychia and Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 2023. Are Alzheimer's and coronary artery diseases genetically related to longevity? Frontiers in Psychiatry 13 10.3389/fpsyt.2022.1102347

Crawford, Karen, Leonenko, Ganna ORCID: https://orcid.org/0000-0001-8025-661X, Baker, Emily, Grozeva, Detelina ORCID: https://orcid.org/0000-0003-3239-8415, Lan-Leung, Benoit, Holmans, Peter ORCID: https://orcid.org/0000-0003-0870-9412, Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259, O'Donovan, Michael C. ORCID: https://orcid.org/0000-0001-7073-2379, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 and Ivanov, Dobril K. ORCID: https://orcid.org/0000-0001-6271-6301 2022. Golgi apparatus, endoplasmic reticulum and mitochondrial function implicated in Alzheimer's disease through polygenic risk and RNA sequencing. Molecular Psychiatry 10.1038/s41380-022-01926-8

Stevenson-Hoare, Joshua O., Heslegrave, Amanda, Leonenko, Ganna ORCID: https://orcid.org/0000-0001-8025-661X, Fathalla, Dina, Bellou, Eftychia, Luckcuck, Lauren, Marshall, Rachel, Sims, Rebecca ORCID: https://orcid.org/0000-0002-3885-1199, Morgan, Paul ORCID: https://orcid.org/0000-0003-4075-7676, Hardy, John A., de Strooper, Bart, Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259, Zetterberg, Henrik and Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 2022. Blood plasma biomarkers improve prediction accuracy over and above genetic predictors of Alzheimer's disease [Abstract]. Alzheimer's & Dementia: The Journal of the Alzheimer's Association 18 (S6) , e064192. 10.1002/alz.064192

Mirza-Davies, Anastasia, Foley, Sonya ORCID: https://orcid.org/0000-0002-8390-2709, Caseras, Xavier ORCID: https://orcid.org/0000-0002-8490-6891, Baker, Emily, Holmans, Peter ORCID: https://orcid.org/0000-0003-0870-9412, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Jones, Derek K ORCID: https://orcid.org/0000-0003-4409-8049, Harrison, Judith R ORCID: https://orcid.org/0000-0002-5775-2524 and Messaritaki, Eirini ORCID: https://orcid.org/0000-0002-9917-4160 2022. The impact of genetic risk for Alzheimer’s disease on the structural brain networks of young adults. Frontiers in Neuroscience 16 , 987677. 10.3389/fnins.2022.987677

Bracher-Smith, Matthew, Leonenko, Ganna ORCID: https://orcid.org/0000-0001-8025-661X, Baker, Emily, Crawford, Karen, Graham, Andrew, Salih, Dervis, Howell, Brian, Hardy, John and Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 2022. Whole genome analysis in APOE4 homozygotes identifies the DAB1-RELN pathway in Alzheimer’s disease pathogenesis. Neurobiology of Aging 119 , pp. 67-76. 10.1016/j.neurobiolaging.2022.07.009

Hardy, John, de Strooper, Bart and Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 2022. Alzheimer’s disease and type 2 diabetes: shared genetic susceptibility? The Lancet Neurology 21 (11) , pp. 962-964. 10.1016/S1474-4422(22)00395-7

Watts, Katie, Wills, Christopher, Madi, Ayman, Palles, Claire, Maughan, Timothy S., Kaplan, Richard, Al-Tassan, Nada A., Kerr, Rachel, Kerr, David J., Houlston, Richard S., Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 and Cheadle, Jeremy P. ORCID: https://orcid.org/0000-0001-9453-8458 2022. Genetic variation in ST6GAL1 is a determinant of capecitabine and oxaliplatin induced hand-foot syndrome. International Journal of Cancer 151 (6) , pp. 957-966. 10.1002/ijc.34046

Bracher-Smith, Matthew, Rees, Elliott ORCID: https://orcid.org/0000-0002-6168-9222, Menzies, Georgina ORCID: https://orcid.org/0000-0002-6600-6507, Walters, James ORCID: https://orcid.org/0000-0002-6980-4053, O'Donovan, Michael ORCID: https://orcid.org/0000-0001-7073-2379, Owen, Michael J. ORCID: https://orcid.org/0000-0003-4798-0862, Kirov, George ORCID: https://orcid.org/0000-0002-3427-3950 and Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 2022. Machine learning for prediction of schizophrenia using genetic and demographic factors in the UK Biobank. Schizophrenia Research 246 , pp. 156-164. 10.1016/j.schres.2022.06.006

Hou, Jiahui, Hess, Jonathan L., Armstrong, Nicola, Bis, Joshua C., Grenier-Boley, Benjamin, Karlsson, Ida K., Leonenko, Ganna ORCID: https://orcid.org/0000-0001-8025-661X, Numbers, Katya, O’Brien, Eleanor K., Shadrin, Alexey, Thalamuthu, Anbupalam, Yang, Qiong, Andreassen, Ole A., Brodaty, Henry, Gatz, Margaret, Kochan, Nicole A., Lambert, Jean-Charles, Laws, Simon M., Masters, Colin L., Mather, Karen A., Pedersen, Nancy L., Posthuma, Danielle, Sachdev, Perminder S., Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259, Fan, Chun Chieh, Faraone, Stephen V., Fennema-Notestine, Christine, Lin, Shu-Ju, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Holmans, Peter ORCID: https://orcid.org/0000-0003-0870-9412, Seshadri, Sudha, Tsuang, Ming T., Kremen, William S. and Glatt, Stephen J. 2022. Polygenic resilience scores capture protective genetic effects for Alzheimer’s disease. Translational Psychiatry 12 (1) , 296. 10.1038/s41398-022-02055-0

Crawford, Karen, Leonenko, Ganna ORCID: https://orcid.org/0000-0001-8025-661X, Baker, Emily, Grozeva, Detelina ORCID: https://orcid.org/0000-0003-3239-8415, Lan-Leung, Benoit, Holmans, Peter ORCID: https://orcid.org/0000-0003-0870-9412, Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259, O'Donovan, Michael ORCID: https://orcid.org/0000-0001-7073-2379, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 and Ivanov, Dobril ORCID: https://orcid.org/0000-0001-6271-6301 2022. Analysis of Alzheimer's disease Polygenic Risk Scores using RNA-sequencing provides further novel biological pathways. [Online]. medRxiv: Cold Spring Harbor Laboratory. Available at: https://doi.org/10.1101/2022.06.29.22276952

Martin-Flores, Nuria, Podpolny, Marina, McLeod, Faye, Crawford, Karen, Ivanov, Dobril ORCID: https://orcid.org/0000-0001-6271-6301, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 and Salinas, Patricia 2022. Restoring synapse integrity and memory in Alzheimer’s disease by downregulation of the Wnt antagonist Dickkopf-3. [Online]. bioRxiv: bioRxiv. Available at: https://www.biorxiv.org/content/10.1101/2022.06.16...

Chambers, Tom, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Legge, Sophie, Baker, Emily, Singh, Krish ORCID: https://orcid.org/0000-0002-3094-2475, Walters, James T. R. ORCID: https://orcid.org/0000-0002-6980-4053, Caseras, Xavier ORCID: https://orcid.org/0000-0002-8490-6891 and Anney, Richard J. L. ORCID: https://orcid.org/0000-0002-6083-407X 2022. Genetic common variants associated with cerebellar volume and their overlap with mental disorders: a study on 33,265 individuals from the UK-Biobank. Molecular Psychiatry 27 , pp. 2282-2290. 10.1038/s41380-022-01443-8

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Sierksma, Annerieke, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 and De Strooper, Bart 2020. Translating genetic risk of Alzheimer’s disease into mechanistic insight and drug targets. Science 370 (6512) , pp. 61-66. 10.1126/science.abb8575

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Cooksey, Roxanne, Kennedy, Jonathan, Dennis, Michael, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Lyons, Ronan and Seaborne, Michael 2020. Proton pump inhibitors and dementia risk: evidence from a cohort study using linked routinely collected national health data in Wales, UK. PLoS ONE 15 (9) , e0237676. 10.1371/journal.pone.0237676

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Bellou, Eftychia, Stevenson-Hoare, Joshua and Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 2020. Polygenic risk and pleiotropy in neurodegenerative diseases. Neurobiology of Disease 142 , 104953. 10.1016/j.nbd.2020.104953

Baker, Emily and Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 2020. Polygenic risk scores in Alzheimer’s disease: current applications and future directions. Frontiers in Digital Health: Personalized Medicine 2 (14) 10.3389/fdgth.2020.00014

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Lewis, Katie J.S., Richards, Alexander, Karlsson, Robert, Leonenko, Ganna ORCID: https://orcid.org/0000-0001-8025-661X, Jones, Samuel E. ORCID: https://orcid.org/0000-0001-5821-5889, Jones, Hannah J. ORCID: https://orcid.org/0000-0001-5821-5889, Gordon-Smith, Katherine, Forty, Liz, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Owen, Michael J. ORCID: https://orcid.org/0000-0003-4798-0862, Weedon, Michael N., Jones, Lisa ORCID: https://orcid.org/0000-0001-5821-5889, Craddock, Nick ORCID: https://orcid.org/0000-0003-2171-0610, Jones, Ian ORCID: https://orcid.org/0000-0001-5821-5889, Landén, Mikael, O'Donovan, Michael C. ORCID: https://orcid.org/0000-0001-7073-2379 and Di Florio, Arianna ORCID: https://orcid.org/0000-0003-0338-2748 2020. Comparison of genetic liability for sleep traits among individuals with Bipolar Disorder I or II and control participants. JAMA Psychiatry 77 (3) , pp. 303-310. 10.1001/jamapsychiatry.2019.4079

Harrison, Judith R. ORCID: https://orcid.org/0000-0002-5775-2524, Mistry, Sumit, Muskett, Natalie and Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 2020. From polygenic scores to precision medicine in Alzheimer’s Disease: A systematic review. Journal of Alzheimer's Disease 74 (4) , pp. 1271-1283. 10.3233/JAD-191233

Glanville, Kylie P., Coleman, Jonathan R.I., Hanscombe, Ken B., Euesden, Jack, Choi, Shing Wan, Purves, Kirstin L., Breen, Gerome, Air, Tracy M., Andlauer, Till F.M., Baune, Bernhard T., Binder, Elisabeth B., Blackwood, Douglas H.R., Boomsma, Dorret I., Buttenschøn, Henriette N., Colodro-Conde, Lucía, Dannlowski, Udo, Direk, Nese, Dunn, Erin C., Forstner, Andreas J., de Geus, Eco J.C., Grabe, Hans J., Hamilton, Steven P., Jones, Ian ORCID: https://orcid.org/0000-0001-5821-5889, Jones, Lisa A., Knowles, James A., Kutalik, Zoltán, Levinson, Douglas F., Lewis, Glyn, Lind, Penelope A., Lucae, Susanne, Magnusson, Patrik K., McGuffin, Peter, McIntosh, Andrew M., Milaneschi, Yuri, Mors, Ole, Mostafavi, Sara, Müller-Myhsok, Bertram, Pedersen, Nancy L., Penninx, Brenda W.J.H., Potash, James B., Preisig, Martin, Ripke, Stephan, Shi, Jianxin, Shyn, Stanley I., Smoller, Jordan W., Streit, Fabian, Sullivan, Patrick F., Tiemeier, Henning, Uher, Rudolf, Van der Auwera, Sandra, Weissman, Myrna M., O'Reilly, Paul F., Lewis, Cathryn M., Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, Tracy M., Andlauer, Till F.M., Bacanu, Silviu-Alin, Bækvad-Hansen, Marie, Beekman, Aartjan T.F., Bigdeli, Tim B., Binder, Elisabeth B., Bryois, Julien, Buttenschøn, Henriette N., Bybjerg-Grauholm, Jonas, Cai, Na, Castelao, Enrique, Christensen, Jane Hvarregaard, Clarke, Toni-Kim, Coleman, Jonathan R.I., Colodro-Conde, Lucía, Couvy-Duchesne, Baptiste, Craddock, Nicholas ORCID: https://orcid.org/0000-0003-2171-0610, Crawford, Gregory E., Davies, Gail, Deary, Ian J., Degenhardt, Franziska, Derks, Eske M., Direk, Nese, Dolan, Conor V., Dunn, Erin C., Eley, Thalia C., Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Hassan Kiadeh, Farnush Farhadi, Finucane, Hilary K., Foo, Jerome C., Forstner, Andreas J., Frank, Josef, Gaspar, Héléna A., Gill, Michael, Goes, Fernando S., Gordon, Scott D., Grove, Jakob, Hall, Lynsey, Hansen, Christine Søholm, Hansen, Thomas F., Herms, Stefan, Hickie, Ian B., Hoffmann, Per, Homuth, Georg, Horn, Carsten, Hottenga, Jouke-Jan, Hougaard, David M., Howard, David M., Ising, Marcus, Jansen, Rick, Jones, Ian ORCID: https://orcid.org/0000-0001-5821-5889, Jones, Lisa A., Jorgenson, Eric, Knowles, James A., Kohane, Isaac S., Kraft, Julia, Kretzschmar, Warren W., Kutalik, Zoltán, Li, Yihan, Lind, Penelope A., MacIntyre, Donald J., MacKinnon, Dean F., Maier, Robert M., Maier, Wolfgang, Marchini, Jonathan, Mbarek, Hamdi, McGrath, Patrick, McGuffin, Peter, Medland, Sarah E., Mehta, Divya, Middeldorp, Christel M., Mihailov, Evelin, Milaneschi, Yuri, Milani, Lili, Mondimore, Francis M., Montgomery, Grant W., Mostafavi, Sara, Mullins, Niamh, Nauck, Matthias, Ng, Bernard, Nivard, Michel G., Nyholt, Dale R., O'Reilly, Paul F., Oskarsson, Hogni, Owen, Michael J ORCID: https://orcid.org/0000-0003-4798-0862, Painter, Jodie N., Pedersen, Carsten Bøcker, Pedersen, Marianne Giørtz, Peterson, Roseann E., Pettersson, Erik, Peyrot, Wouter J., Pistis, Giorgio, Posthuma, Danielle, Quiroz, Jorge A., Qvist, Per, Rice, John P., Riley, Brien P., Rivera, Margarita, Mirza, Saira Saeed, Schoevers, Robert, Schulte, Eva C., Shen, Ling, Shi, Jianxin, Shyn, Stanley I., Sigurdsson, Engilbert, Sinnamon, Grant C.B., Smit, Johannes H., Smith, Daniel J., Stefansson, Hreinn, Steinberg, Stacy, Streit, Fabian, Strohmaier, Jana, Tansey, Katherine E., Teismann, Henning, Teumer, Alexander, Thompson, Wesley, Thomson, Pippa A., Thorgeirsson, Thorgeir E., Traylor, Matthew, Treutlein, Jens, Trubetskoy, Vassily, Uitterlinden, Andrés G., Umbricht, Daniel, Van der Auwera, Sandra, van Hemert, Albert M., Viktorin, Alexander, Visscher, Peter M., Wang, Yunpeng, Webb, Bradley T., Weinsheimer, Shantel Marie, Wellmann, Jürgen, Willemsen, Gonneke, Witt, Stephanie H., Wu, Yang, Xi, Hualin S., Yang, Jian, Zhang, Futao, Arolt, Volker, Baune, Bernhard T., Berger, Klaus, Boomsma, Dorret I., Cichon, Sven, Dannlowski, Udo, de Geus, E.J.C., DePaulo, J. 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Rees, Elliott ORCID: https://orcid.org/0000-0002-6168-9222, GROUP Investigators, Han, Jun, Morgan, Joanne, Carrera, Noa ORCID: https://orcid.org/0000-0003-0739-0382, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Pocklington, Andrew J. ORCID: https://orcid.org/0000-0002-2137-0452, Duffield, Madeleine, Hall, Lynsey S., Legge, Sophie E., Pardinas, Antonio F. ORCID: https://orcid.org/0000-0001-6845-7590, Richards, Alexander L., Roth, Julian, Lezheiko, Tatyana, Kondratyev, Nikolay, Golimbat, Vera, Parellada, Mara, González-Peñas, Javier, Arango, Celso, Gawlik, Micha, Kirov, George ORCID: https://orcid.org/0000-0002-3427-3950, Walters, James T. R. ORCID: https://orcid.org/0000-0002-6980-4053, Holmans, Peter ORCID: https://orcid.org/0000-0003-0870-9412, O'Donovan, Michael C. ORCID: https://orcid.org/0000-0001-7073-2379 and Owen, Michael J. ORCID: https://orcid.org/0000-0003-4798-0862 2020. De novo mutations identified by exome sequencing implicate rare missense variants in SLC6A1 in schizophrenia. Nature Neuroscience 23 (2) , pp. 179-184. 10.1038/s41593-019-0565-2

Orme, Tatiana, Hernandez, Dena, Ross, Owen A., Kun-Rodrigues, Celia, Darwent, Lee, Shepherd, Claire E., Parkkinen, Laura, Ansorge, Olaf, Clark, Lorraine, Honig, Lawrence S., Marder, Karen, Lemstra, Afina, Rogaeva, Ekaterina, St. George-Hyslop, Peter, Londos, Elisabet, Zetterberg, Henrik, Morgan, Kevin, Troakes, Claire, Al-Sarraj, Safa, Lashley, Tammaryn, Holton, Janice, Compta, Yaroslau, Van Deerlin, Vivianna, Trojanowski, John Q., Serrano, Geidy E., Beach, Thomas G., Lesage, Suzanne, Galasko, Douglas, Masliah, Eliezer, Santana, Isabel, Pastor, Pau, Tienari, Pentti J., Myllykangas, Liisa, Oinas, Minna, Revesz, Tamas, Lees, Andrew, Boeve, Brad F., Petersen, Ronald C., Ferman, Tanis J., Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Graff-Radford, Neill, Cairns, Nigel J., Morris, John C., Pickering-Brown, Stuart, Mann, David, Halliday, Glenda, Stone, David J., Dickson, Dennis W., Hardy, John, Singleton, Andrew, Guerreiro, Rita and Bras, Jose 2020. Analysis of neurodegenerative disease-causing genes in dementia with Lewy bodies. Acta Neuropathologica Communications 8 (1) , 5. 10.1186/s40478-020-0879-z

Summers, Matthew G. ORCID: https://orcid.org/0000-0001-6387-124X, Maughan, Timothy S., Kaplan, Richard, Law, Philip J., Houlston, Richard S., Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 and Cheadle, Jeremy P. ORCID: https://orcid.org/0000-0001-9453-8458 2020. Comprehensive analysis of colorectal cancer-risk loci and survival outcome: a prognostic role for CDH1 variants. European Journal Of Cancer 124 , pp. 56-63. 10.1016/j.ejca.2019.09.024

Hall, Lynsey S, Medway, Christopher W ORCID: https://orcid.org/0000-0002-1764-0587, Pain, Oliver, Pardinas, Antonio F ORCID: https://orcid.org/0000-0001-6845-7590, Rees, Elliott G ORCID: https://orcid.org/0000-0002-6168-9222, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Pocklington, Andrew ORCID: https://orcid.org/0000-0002-2137-0452, Bray, Nicholas J ORCID: https://orcid.org/0000-0002-4357-574X, Holmans, Peter A ORCID: https://orcid.org/0000-0003-0870-9412, Walters, James T R ORCID: https://orcid.org/0000-0002-6980-4053, Owen, Michael ORCID: https://orcid.org/0000-0003-4798-0862 and O'Donovan, Michael ORCID: https://orcid.org/0000-0001-7073-2379 2020. A transcriptome-wide association study implicates specific pre- and post-synaptic abnormalities in schizophrenia. Human Molecular Genetics 29 (1) , pp. 159-167. 10.1093/hmg/ddz253

Legge, Sophie E., Jones, Hannah J., Kendall, Kimberley M. ORCID: https://orcid.org/0000-0002-6755-6121, Pardinas, Antonio F. ORCID: https://orcid.org/0000-0001-6845-7590, Menzies, Georgina ORCID: https://orcid.org/0000-0002-6600-6507, Bracher-Smith, Matthew, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Rees, Elliott ORCID: https://orcid.org/0000-0002-6168-9222, Davis, Katrina A., Hotopf, Matthew, Savage, Jeanne E., Posthuma, Danielle, Holmans, Peter ORCID: https://orcid.org/0000-0003-0870-9412, Kirov, George ORCID: https://orcid.org/0000-0002-3427-3950, Owen, Michael J. ORCID: https://orcid.org/0000-0003-4798-0862, O'Donovan, Michael C. ORCID: https://orcid.org/0000-0001-7073-2379, Zammit, Stanley ORCID: https://orcid.org/0000-0002-2647-9211 and Walters, James T. R. ORCID: https://orcid.org/0000-0002-6980-4053 2019. Association of genetic liability to psychotic experiences with neuropsychotic disorders and traits. JAMA Psychiatry 76 (12) , pp. 1256-1265. 10.1001/jamapsychiatry.2019.2508

Mistry, Sumit, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Di Florio, Arianna ORCID: https://orcid.org/0000-0003-0338-2748, Smith, Daniel and Zammit, Stanley ORCID: https://orcid.org/0000-0002-2647-9211 2019. Investigating associations between genetic risk for bipolar disorder and cognitive functioning in childhood. Journal of Affective Disorders 259 , pp. 112-120. 10.1016/j.jad.2019.08.040

Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Smith, Daniel J., Kendall, Kimberley ORCID: https://orcid.org/0000-0002-6755-6121, Ward, Joey, Kirov, George ORCID: https://orcid.org/0000-0002-3427-3950, Owen, Michael J. ORCID: https://orcid.org/0000-0003-4798-0862, Walters, James ORCID: https://orcid.org/0000-0002-6980-4053 and O'Donovan, Michael C. ORCID: https://orcid.org/0000-0001-7073-2379 2019. Polygenic risk for schizophrenia and season of birth within the UK Biobank cohort. Psychological Medicine 49 (15) , pp. 2499-2504. 10.1017/S0033291718000454

Hardy, John and Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 2019. Genes, pathways and risk prediction in Alzheimer's disease. Human Molecular Genetics 28 (R2) , R235-R240. 10.1093/hmg/ddz163

Salih, Dervis A, Bayram, Sevinc, Guelfi, Sebastian, Reynolds, Regina H, Shoai, Maryam, Ryten, Mina, Brenton, Jonathan, Zhang, David, Matarin, Mar, Botia, Juan A, Shah, Runil, Brookes, Keeley J, Guetta-Baranes, Tamar, Morgan, Kevin, Bellou, Eftychia, Cummings, Damian M, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 and Hardy, John 2019. Genetic variability in response to amyloid beta deposition influences Alzheimer's disease risk. Brain Communications 1 (1) , -. 10.1093/braincomms/fcz022

Leonenko, Ganna ORCID: https://orcid.org/0000-0001-8025-661X, Shoai, Maryam, Bellou, Eftychia, Sims, Rebecca ORCID: https://orcid.org/0000-0002-3885-1199, Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259, Hardy, John, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 and the Alzheimer's Disease Neuroimaging Initiative 2019. Genetic risk for Alzheimer's disease is distinct from genetic risk for amyloid deposition. Annals of Neurology 86 (3) , pp. 427-435. 10.1002/ana.25530

Gray, Victoria, Briggs, Sarah, Palles, Claire, Jaegar, Emma, Iveson, Timothy, Kerr, Rachel, Saunders, Mark P., Paul, James, Harkin, Andrea, McQueen, John, Summers, Matthew G., Johnstone, Elaine, Wang, Haitao, Gatcombe, Laura, Maughan, Timothy S., Kaplan, Richard, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Al-Tassan, Nada A., Meyer, Brian F., Wakil, Salma M., Houlston, Richard S., Cheadle, Jeremy P. ORCID: https://orcid.org/0000-0001-9453-8458, Tomlinson, Ian and Church, David N. 2019. Pattern recognition receptor polymorphisms as predictors of oxaliplatin benefit in colorectal cancer. JNCI: Journal of the National Cancer Institute 111 (8) , pp. 828-836. 10.1093/jnci/djy215

Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Pardinas, Antonio F. ORCID: https://orcid.org/0000-0001-6845-7590, Santiago, Enrique, Walters, James ORCID: https://orcid.org/0000-0002-6980-4053, Kirov, George ORCID: https://orcid.org/0000-0002-3427-3950, Owen, Michael J. ORCID: https://orcid.org/0000-0003-4798-0862 and O'Donovan, Michael C. ORCID: https://orcid.org/0000-0001-7073-2379 2019. The relationship between common variant schizophrenia liability and number of offspring in the UK Biobank. American Journal of Psychiatry 176 (8) , pp. 661-666. 10.1176/appi.ajp.2018.18020140

Baker, Emily, Sims, Rebecca ORCID: https://orcid.org/0000-0002-3885-1199, Leonenko, Ganna ORCID: https://orcid.org/0000-0001-8025-661X, Frizzati, Aura ORCID: https://orcid.org/0000-0002-7002-6180, Harwood, Janet, Grozeva, Detelina ORCID: https://orcid.org/0000-0003-3239-8415, Morgan, Kevin ORCID: https://orcid.org/0000-0003-4075-7676, Passmore, Peter, Holmes, Clives, Powell, John, Brayne, Carol, Gill, Michael, Mead, Simon, Bossu, Paola, Spalletta, Gianfranco, Goate, Alison, Crunchaga, Carlos, Maier, Wolfgang, Heun, Reinhard, Jessen, Frank, Peters, Oliver, Dichgans, Martin, Frolich, Lutz, Ramirez, Alfredo, Jones, Lesley ORCID: https://orcid.org/0000-0002-3007-4612, Hardy, John, Ivanov, Dobril ORCID: https://orcid.org/0000-0001-6271-6301, Hill, Matthew ORCID: https://orcid.org/0000-0001-6776-8709, Holmans, Peter ORCID: https://orcid.org/0000-0003-0870-9412, Allen, Nicholas ORCID: https://orcid.org/0000-0003-4009-186X, Morgan, Paul ORCID: https://orcid.org/0000-0003-4075-7676, Seshadri, Sudha, Schellenberg, Gerard, Amouvel, Philippe, Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259 and Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 2019. Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer’s disease. PLoS ONE 14 (7) , e0218111. 10.1371/journal.pone.0218111

Guerreiro, Rita, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Hernandez, Dena G., Kun-Rodrigues, Celia, Ross, Owen A., Orme, Tatiana, Neto, Joao Luis, Carmona, Susana, Dehghani, Nadia, Eicher, John D., Shepherd, Claire, Parkkinen, Laura, Darwent, Lee, Heckman, Michael G., Scholz, Sonja W., Troncoso, Juan C., Pletnikova, Olga, Dawson, Ted, Rosenthal, Liana, Ansorge, Olaf, Clarimon, Jordi, Lleo, Alberto, Morenas-Rodriguez, Estrella, Clark, Lorraine, Honig, Lawrence S., Marder, Karen, Lemstra, Afina, Rogaeva, Ekaterina, St. George-Hyslop, Peter, Londos, Elisabet, Zetterberg, Henrik, Barber, Imelda, Braae, Anne, Brown, Kristelle, Morgan, Kevin, Troakes, Claire, Al-Sarraj, Safa, Lashley, Tammaryn, Holton, Janice, Compta, Yaroslau, Van Deerlin, Vivianna, Serrano, Geidy E., Beach, Thomas G., Lesage, Suzanne, Galasko, Douglas, Masliah, Eliezer, Santana, Isabel, Pastor, Pau, Diez-Fairen, Monica, Aguilar, Miquel, Tienari, Pentti J., Myllykangas, Liisa, Oinas, Minna, Revesz, Tamas, Lees, Andrew, Boeve, Brad F., Petersen, Ronald C., Ferman, Tanis J., Graff-Radford, Neill, Cairns, Nigel J., Morris, John C., Pickering-Brown, Stuart, Mann, David, Halliday, Glenda M., Hardy, John, Trojanowski, John Q., Dickson, Dennis W., Singleton, Andrew, Stone, David J. and Bras, Jose 2019. Heritability and genetic variance of dementia with Lewy bodies. Neurobiology of Disease 127 , pp. 492-501. 10.1016/j.nbd.2019.04.004

Czamara, Darina, Eraslan, Gökçen, Page, Christian M., Lahti, Jari, Lahti-Pulkkinen, Marius, Hämäläinen, Esa, Kajantie, Eero, Laivuori, Hannele, Villa, Pia M., Reynolds, Rebecca M., Nystad, Wenche, Håberg, Siri E., London, Stephanie J., O'Donnell, Kieran J., Garg, Elika, Meaney, Michael J., Entringer, Sonja, Wadhwa, Pathik D., Buss, Claudia, Jones, Meaghan J., Lin, David T. S., MacIsaac, Julie L., Kobor, Michael S., Koen, Nastassja, Zar, Heather J., Koenen, Karestan C., Dalvie, Shareefa, Stein, Dan J., Kondofersky, Ivan, Müller, Nikola S., Theis, Fabian J., Räikkönen, Katri, Binder, Elisabeth B., Craddock, Nick ORCID: https://orcid.org/0000-0003-2171-0610, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Owen, Michael J. ORCID: https://orcid.org/0000-0003-4798-0862 and O'Donovan, Michael C. ORCID: https://orcid.org/0000-0001-7073-2379 2019. Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns. Nature Communications 10 , 2548. 10.1038/s41467-019-10461-0

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Strawbridge, Rona J., Ward, Joey, Cullen, Breda, Tunbridge, Elizabeth M., Hartz, Sarah, Bierut, Laura, Horton, Amy, Bailey, Mark E. S., Graham, Nicholas, Ferguson, Amy, Lyall, Donald M., Mackay, Daniel, Pidgeon, Laura M., Cavanagh, Joanathan, Pell, Jill P., O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Harrison, Paul J. and Smith, Daniel J. 2018. Genome-wide analysis of self-reported risk-taking behaviour and cross-disorder genetic correlations in the UK Biobank cohort. Translational Psychiatry 8 , 39. 10.1038/s41398-017-0079-1

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Guerreiro, Rita, Ross, Owen A., Kun-Rodrigues, Celia, Hernandez, Dena G., Orme, Tatiana, Eicher, John D., Shepherd, Claire E., Parkkinen, Laura, Darwent, Lee, Heckman, Michael G., Scholz, Sonja W., Troncoso, Juan C., Pletnikova, Olga, Ansorge, Olaf, Clarimon, Jordi, Lleo, Alberto, Morenas-Rodriguez, Estrella, Clark, Lorraine, Honig, Lawrence S., Marder, Karen, Lemstra, Afina, Rogaeva, Ekaterina, St George-Hyslop, Peter, Londos, Elisabet, Zetterberg, Henrik, Barber, Imelda, Braae, Anne, Brown, Kristelle, Morgan, Kevin, Troakes, Claire, Al-Sarraj, Safa, Lashley, Tammaryn, Holton, Janice, Compta, Yaroslau, Van Deerlin, Vivianna, Serrano, Geidy E., Beach, Thomas G., Lesage, Suzanne, Galasko, Douglas, Masliah, Eliezer, Santana, Isabel, Pastor, Pau, Diez-Fairen, Monica, Aguilar, Miquel, Tienari, Pentti J., Myllykangas, Liisa, Oinas, Minna, Revesz, Tamas, Lees, Andrew, Boeve, Brad F., Petersen, Ronald C., Ferman, Tanis J., Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Graff-Radford, Neill, Cairns, Nigel J., Morris, John C., Pickering-Brown, Stuart, Mann, David, Halliday, Glenda M., Hardy, John, Trojanowski, John Q., Dickson, Dennis W., Singleton, Andrew, Stone, David J. and Bras, Jose 2018. Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study. Lancet Neurology 17 (1) , pp. 64-74. 10.1016/S1474-4422(17)30400-3

Ward, Joey, Strawbridge, Rona J., Bailey, Mark E. S., Graham, Nicholas, Ferguson, Amy, Lyall, Donald M., Cullen, Brenda, Pidgeon, Laura M., Cavanagh, Jonathan, Mackay, Daniel F., Pell, Jill P., O'Donovan, Michael ORCID: https://orcid.org/0000-0001-7073-2379, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 and Smith, Daniel J. 2017. Genome-wide analysis in UK Biobank identifies four loci associated with mood instability and genetic correlation with MDD, anxiety disorder and schizophrenia. Translational Psychiatry 7 , 1264. 10.1038/s41398-017-0012-7

Rietschel, Liz, Streit, Fabian, Zhu, Gu, McAloney, Kerrie, Frank, Josef, Couvy-Duchesne, Baptiste, Witt, Stephanie H., Binz, Tina M., McGrath, John, Hickie, Ian B., Hansell, Narelle K., Wright, Margaret J., Gillespie, Nathan A., Forstner, Andreas J., Schulze, Thomas G., Wüst, Stefan, Nöthen, Markus M., Baumgartner, Markus R., Walker, Brian R., Crawford, Andrew A., Colodro-Conde, Lucía, Medland, Sarah E., Martin, Nicholas G., Rietschel, Marcella and Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 2017. Hair cortisol in twins: Heritability and genetic overlap with psychological variables and stress-system genes. Scientific Reports 7 (1) , 15351. 10.1038/s41598-017-11852-3

Mistry, Sumit, Zammit, Stanley ORCID: https://orcid.org/0000-0002-2647-9211, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Jones, Hannah J. and Smith, Daniel J. 2017. Borderline personality and attention-deficit hyperactivity traits in childhood are associated with hypomanic features in early adulthood. Journal of affective disorders 221 , pp. 246-253. 10.1016/j.jad.2017.06.039

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