Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Browse by Current Cardiff authors

[up] Up a level
Number of items: 23.

Bellou, Eftychia, Kim, Woori, Leonenko, Ganna ORCID: https://orcid.org/0000-0001-8025-661X, Tao, Feifei, Simmonds, Emily, Wu, Ying, Mattsson-Carlgren, Niklas, Hansson, Oskar, Nagle, Michael W. and Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 2025. Benchmarking Alzheimer's disease prediction: personalised risk assessment using polygenic risk scores across various methodologies and genome-wide studies. Alzheimer's Research and Therapy 17 (1) , 6. 10.1186/s13195-024-01664-9
file

Simmonds, Emily, Leonenko, Ganna ORCID: https://orcid.org/0000-0001-8025-661X, Yaman, Umran, Bellou, Eftychia, Myers, Amanda, Morgan, Kevin, Brookes, Keeley, Hardy, John, Salih, Dervis and Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 2024. Chromosome X-wide association study in case control studies of pathologically confirmed Alzheimer’s disease in a European population. Translational Psychiatry 14 (1) , 358. 10.1038/s41398-024-03058-9
file

Stevenson-Hoare, Joshua, Legge, Sophie E., Simmonds, Emily, Han, Jun, Owen, Michael J. ORCID: https://orcid.org/0000-0003-4798-0862, O'Donovan, Michael ORCID: https://orcid.org/0000-0001-7073-2379, Kirov, George ORCID: https://orcid.org/0000-0002-3427-3950 and Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 2024. Severe psychiatric disorders are associated with increased risk of dementia. BMJ Mental Health 27 (1) , e301097. 10.1136/bmjment-2024-301097
file

Leonenko, Ganna ORCID: https://orcid.org/0000-0001-8025-661X, Bauermeister, Sarah, Ghanti, Dipanwita, Stevenson-Hoare, Joshua, Simmonds, Emily, Brookes, Keeley, Morgan, Kevin, Chaturvedi, Nishi, Elliot, Paul, Sudlow, Cathie, Thomas, Alan, Wareham, Nicholas, Gallacher, John and Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 2024. Dementias Platform UK: Bringing genetics into life. Alzheimer's & Dementia: The Journal of the Alzheimer's Association 20 (5) , pp. 3281-3289. 10.1002/alz.13782
file

Steventon, Jessica J., Lancaster, Thomas M., Simmonds Baker, Emily, Bracher-Smith, Matthew, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Ruth, Katherine S., Davies, William ORCID: https://orcid.org/0000-0002-7714-2440, Caseras, Xavier ORCID: https://orcid.org/0000-0002-8490-6891 and Murphy, Kevin ORCID: https://orcid.org/0000-0002-6516-313X 2023. Menopause age, reproductive span and hormone therapy duration predict the volume of medial temporal lobe brain structures in postmenopausal women. Psychoneuroendocrinology 158 , 106393. 10.1016/j.psyneuen.2023.106393
file

Harrison, Judith R. ORCID: https://orcid.org/0000-0002-5775-2524, Foley, Sonya F. ORCID: https://orcid.org/0000-0002-8390-2709, Baker, Emily, Bracher-Smith, Matthew, Holmans, Peter ORCID: https://orcid.org/0000-0003-0870-9412, Stergiakouli, Evie, Linden, David E.J. ORCID: https://orcid.org/0000-0002-5638-9292, Caseras, Xavier ORCID: https://orcid.org/0000-0002-8490-6891, Jones, Derek K. ORCID: https://orcid.org/0000-0003-4409-8049 and Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 2023. Pathway-specific polygenic scores for Alzheimer's disease are associated with changes in brain structure in younger and older adults. Brain Communications 5 (5) , fcad229. 10.1093/braincomms/fcad229
file

Wren, Georgina, Baker, Emily, Underwood, Jack ORCID: https://orcid.org/0000-0003-1731-6039, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Thompson, Andrew ORCID: https://orcid.org/0000-0001-6788-7222, Kirov, George ORCID: https://orcid.org/0000-0002-3427-3950, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 and Davies, William ORCID: https://orcid.org/0000-0002-7714-2440 2023. Characterising heart rhythm abnormalities associated with Xp22.31 deletion. Journal of Medical Genetics 60 , pp. 636-643. 10.1136/jmg-2022-108862
file

Simmonds, Emily, Leonenko, Ganna ORCID: https://orcid.org/0000-0001-8025-661X, Schmidt, Karl Michael ORCID: https://orcid.org/0000-0002-0227-3024, Hill, Matthew, Myers, Amanda, Shoai, Maryam, de Rojas, Itziar, Tesi, Niccolo, Holstege, Henne, van der Flier, Wiesje, Pijnenburg, Yolande, Ruiz, Agustin, Hardy, John, van der Lee, Sven and Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 2023. What does heritability of Alzheimer’s disease represent? PLoS ONE 18 (4) , e0281440. 10.1371/journal.pone.0281440
file

Crawford, Karen, Leonenko, Ganna ORCID: https://orcid.org/0000-0001-8025-661X, Baker, Emily, Grozeva, Detelina ORCID: https://orcid.org/0000-0003-3239-8415, Lan-Leung, Benoit, Holmans, Peter ORCID: https://orcid.org/0000-0003-0870-9412, Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259, O'Donovan, Michael C. ORCID: https://orcid.org/0000-0001-7073-2379, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 and Ivanov, Dobril K. ORCID: https://orcid.org/0000-0001-6271-6301 2022. Golgi apparatus, endoplasmic reticulum and mitochondrial function implicated in Alzheimer's disease through polygenic risk and RNA sequencing. Molecular Psychiatry 10.1038/s41380-022-01926-8
filefile

Mirza-Davies, Anastasia, Foley, Sonya ORCID: https://orcid.org/0000-0002-8390-2709, Caseras, Xavier ORCID: https://orcid.org/0000-0002-8490-6891, Baker, Emily, Holmans, Peter ORCID: https://orcid.org/0000-0003-0870-9412, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Jones, Derek K ORCID: https://orcid.org/0000-0003-4409-8049, Harrison, Judith R ORCID: https://orcid.org/0000-0002-5775-2524 and Messaritaki, Eirini ORCID: https://orcid.org/0000-0002-9917-4160 2022. The impact of genetic risk for Alzheimer’s disease on the structural brain networks of young adults. Frontiers in Neuroscience 16 , 987677. 10.3389/fnins.2022.987677
file

Bracher-Smith, Matthew, Leonenko, Ganna ORCID: https://orcid.org/0000-0001-8025-661X, Baker, Emily, Crawford, Karen, Graham, Andrew, Salih, Dervis, Howell, Brian, Hardy, John and Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 2022. Whole genome analysis in APOE4 homozygotes identifies the DAB1-RELN pathway in Alzheimer’s disease pathogenesis. Neurobiology of Aging 119 , pp. 67-76. 10.1016/j.neurobiolaging.2022.07.009
filefile

Crawford, Karen, Leonenko, Ganna ORCID: https://orcid.org/0000-0001-8025-661X, Baker, Emily, Grozeva, Detelina ORCID: https://orcid.org/0000-0003-3239-8415, Lan-Leung, Benoit, Holmans, Peter ORCID: https://orcid.org/0000-0003-0870-9412, Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259, O'Donovan, Michael ORCID: https://orcid.org/0000-0001-7073-2379, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 and Ivanov, Dobril ORCID: https://orcid.org/0000-0001-6271-6301 2022. Analysis of Alzheimer's disease Polygenic Risk Scores using RNA-sequencing provides further novel biological pathways. [Online]. medRxiv: Cold Spring Harbor Laboratory. Available at: https://doi.org/10.1101/2022.06.29.22276952

Chambers, Tom, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Legge, Sophie, Baker, Emily, Singh, Krish ORCID: https://orcid.org/0000-0002-3094-2475, Walters, James T. R. ORCID: https://orcid.org/0000-0002-6980-4053, Caseras, Xavier ORCID: https://orcid.org/0000-0002-8490-6891 and Anney, Richard J. L. ORCID: https://orcid.org/0000-0002-6083-407X 2022. Genetic common variants associated with cerebellar volume and their overlap with mental disorders: a study on 33,265 individuals from the UK-Biobank. Molecular Psychiatry 27 , pp. 2282-2290. 10.1038/s41380-022-01443-8
filefile

Leonenko, Ganna ORCID: https://orcid.org/0000-0001-8025-661X, Baker, Emily, Stevenson-Hoare, Joshua, Sierksma, Annerieke, Fiers, Mark, Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259, de Strooper, Bart, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 and Alzheimer's Disease Neuroimaging Initiative 2021. Identifying individuals with high risk of Alzheimer’s disease using polygenic risk scores. Nature Communications 12 , 4506.
file

Carpanini, Sarah M., Harwood, Janet C., Baker, Emily, Torvell, Megan, Sims, Rebecca ORCID: https://orcid.org/0000-0002-3885-1199, Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259 and Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 2021. The impact of complement genes on the risk of late-onset Alzheimer's disease. Genes 12 (3) , 443. 10.3390/genes12030443
file

Bellou, Eftychia, Baker, Emily, Leonenko, Ganna ORCID: https://orcid.org/0000-0001-8025-661X, Bracher-Smith, Matthew, Daunt, Paula, Menzies, Georgina ORCID: https://orcid.org/0000-0002-6600-6507, Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259 and Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 2020. Age-dependent effect of APOE and polygenic component on Alzheimer's disease. Neurobiology of Aging 93 , pp. 69-77. 10.1016/j.neurobiolaging.2020.04.024
file

Baker, Emily and Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 2020. Polygenic risk scores in Alzheimer’s disease: current applications and future directions. Frontiers in Digital Health: Personalized Medicine 2 (14) 10.3389/fdgth.2020.00014
file

Baker, Emily, Sims, Rebecca ORCID: https://orcid.org/0000-0002-3885-1199, Leonenko, Ganna ORCID: https://orcid.org/0000-0001-8025-661X, Frizzati, Aura ORCID: https://orcid.org/0000-0002-7002-6180, Harwood, Janet, Grozeva, Detelina ORCID: https://orcid.org/0000-0003-3239-8415, Morgan, Kevin ORCID: https://orcid.org/0000-0003-4075-7676, Passmore, Peter, Holmes, Clives, Powell, John, Brayne, Carol, Gill, Michael, Mead, Simon, Bossu, Paola, Spalletta, Gianfranco, Goate, Alison, Crunchaga, Carlos, Maier, Wolfgang, Heun, Reinhard, Jessen, Frank, Peters, Oliver, Dichgans, Martin, Frolich, Lutz, Ramirez, Alfredo, Jones, Lesley ORCID: https://orcid.org/0000-0002-3007-4612, Hardy, John, Ivanov, Dobril ORCID: https://orcid.org/0000-0001-6271-6301, Hill, Matthew ORCID: https://orcid.org/0000-0001-6776-8709, Holmans, Peter ORCID: https://orcid.org/0000-0003-0870-9412, Allen, Nicholas ORCID: https://orcid.org/0000-0003-4009-186X, Morgan, Paul ORCID: https://orcid.org/0000-0003-4075-7676, Seshadri, Sudha, Schellenberg, Gerard, Amouvel, Philippe, Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259 and Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 2019. Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer’s disease. PLoS ONE 14 (7) , e0218111. 10.1371/journal.pone.0218111
file

Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Baker, Emily, Shoai, Maryam, Leonenko, Ganna ORCID: https://orcid.org/0000-0001-8025-661X, Myers, Amanda J., Huentelman, Matt and Hardy, John 2019. Genetic analysis suggests high misassignment rates in clinical Alzheimer's cases and controls. Neurobiology of Aging 77 , pp. 178-182. 10.1016/j.neurobiolaging.2018.12.002
file

Vivian-Griffiths, Timothy, Baker, Emily, Schmidt, Karl M. ORCID: https://orcid.org/0000-0002-0227-3024, Bracher-Smith, Matthew, Walters, James ORCID: https://orcid.org/0000-0002-6980-4053, Artemiou, Andreas ORCID: https://orcid.org/0000-0002-7501-4090, Holmans, Peter ORCID: https://orcid.org/0000-0003-0870-9412, O'Donovan, Michael C. ORCID: https://orcid.org/0000-0001-7073-2379, Owen, Michael J. ORCID: https://orcid.org/0000-0003-4798-0862, Pocklington, Andrew ORCID: https://orcid.org/0000-0002-2137-0452 and Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 2019. Predictive modeling of schizophrenia from genomic data: Comparison of polygenic risk score with kernel support vector machines approach. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 180 (1) , pp. 80-85. 10.1002/ajmg.b.32705
file

Baker, Emily Ann 2018. Investigation of new strategies for identifying causal mechanisms in Alzheimer's disease taking bioinformatics approaches beyond GWAS. PhD Thesis, Cardiff University.
Item availability restricted.
filefile

Ahmad, Shahzad, Bannister, Christian ORCID: https://orcid.org/0000-0001-8558-9480, van der Lee, Sven J., Vojinovic, Dina, Adams, Hieab H.H., Ramirez, Alfredo, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Sims, Rebecca ORCID: https://orcid.org/0000-0002-3885-1199, Baker, Emily, Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259, Holmans, Peter ORCID: https://orcid.org/0000-0003-0870-9412, Vernooij, Meike W., Ikram, M. Arfan, Amin, Najaf and van Duijn, Cornelia M. 2018. Disentangling the biological pathways involved in early features of Alzheimer's disease in the Rotterdam Study. Alzheimer's and Dementia 14 (7) , pp. 848-857. 10.1016/j.jalz.2018.01.005
file

Baker, Emily, Schmidt, Karl Michael ORCID: https://orcid.org/0000-0002-0227-3024, Sims, Rebecca ORCID: https://orcid.org/0000-0002-3885-1199, O'Donovan, Michael C. ORCID: https://orcid.org/0000-0001-7073-2379, Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259, Holmans, Peter ORCID: https://orcid.org/0000-0003-0870-9412 and Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 2018. POLARIS: polygenic LD-adjusted risk score approach for set-based analysis of GWAS data. Genetic Epidemiology 42 (4) , pp. 366-377. 10.1002/gepi.22117
file

This list was generated on Sun Mar 9 05:18:19 2025 GMT.


Maintained by Cardiff University Information Services