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Byrne, Robert A.J., Nimmo, Jacqui, Torvell, Megan, Carpanini, Sarah M., Daskoulidou, Nikoleta, Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490, Noble, Lucy V., Veteleanu, Aurora, Watkins, Lewis M., Zelek, Wioleta M., O'Donovan, Michael C. ORCID: https://orcid.org/0000-0001-7073-2379 and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2025. The schizophrenia-associated gene CSMD1 encodes a complement classical pathway inhibitor predominantly expressed by astrocytes and at synapses in mice and humans. Brain, Behavior, and Immunity 127 , pp. 287-302. 10.1016/j.bbi.2025.03.026
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Nguyen, Van Dien, Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490 and Zhou, You ORCID: https://orcid.org/0000-0002-1743-1291 2024. From complement to complosome in non‐alcoholic fatty liver disease: when location matters. Liver International 44 (2) , pp. 316-329. 10.1111/liv.15796
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Mazzarino, Morgane, Cetin, Esra, Bartosova, Maria, Marinovic, Iva, Ipseiz, Natacha ORCID: https://orcid.org/0000-0001-5008-8889, Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490, Schmitt, Claus Peter, Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578, Labéta, Mario O. ORCID: https://orcid.org/0000-0001-5750-6983 and Raby, Anne-Catherine ORCID: https://orcid.org/0000-0002-5354-5835 2023. Therapeutic targeting of chronic kidney disease-associated DAMPs differentially contributing to vascular pathology. Frontiers in Immunology 14 , 1240679. 10.3389/fimmu.2023.1240679
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Chan, Yee-Hung, Moss, Joe W. E. ORCID: https://orcid.org/0000-0002-1866-9752, Williams, Jessica O., Ferekidis, Nele, Alshehri, Nouf, Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490, Menendez Gonzalez, Juan B., Plummer, Sue F., Michael, Daryn R., Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733 and Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578 2023. (+)-catechin attenuates multiple atherosclerosis-associated processes in vitro, modulates disease-associated risk factors in C57BL/6J mice and reduces atherogenesis in LDL receptor deficient mice by inhibiting inflammation and increasing markers of plaque stability. Molecular Nutrition & Food Research 67 (14) , 2200716. 10.1002/mnfr.202200716
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Schroeder, B. E., Robertson, N. P. ORCID: https://orcid.org/0000-0002-5409-4909 and Hughes, T. A. T. ORCID: https://orcid.org/0000-0003-2348-3490 2023. Cerebral amyloid angiopathy: an update. Journal of Neurology 270 , pp. 2809-2811. 10.1007/s00415-023-11631-3
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Webberley, Thomas S., Bevan, Ryan J. ORCID: https://orcid.org/0000-0002-2557-2887, Kerry-Smith, Joshua, Dally, Jordanna, Michael, Daryn R., Thomas, Sophie, Rees, Meg, Morgan, James E. ORCID: https://orcid.org/0000-0002-8920-1065, Marchesi, Julian R., Good, Mark A. ORCID: https://orcid.org/0000-0002-1824-1203, Plummer, Sue F., Wang, Duolao and Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490 2023. Assessment of Lab4P probiotic effects on cognition in 3xTg-AD Alzheimer’s disease model mice and the SH-SY5Y neuronal cell line. International Journal of Molecular Sciences 24 (5) , 4683. 10.3390/ijms24054683
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Seidel, Florine, Kleemann, Robert, van Duyvenvoorde, Wim, van Trigt, Nikki, Keijzer, Nanda, van der Kooij, Sandra, van Kooten, Cees, Verschuren, Lars, Menke, Aswin, Kiliaan, Amanda J., Winter, Johnathan, Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490, Morgan, B. Paul, Baas, Frank, Fluiter, Kees and Morrison, Martine C. 2022. Therapeutic intervention with anti-complement component 5 antibody does not reduce nash but does attenuate atherosclerosis and mif concentrations in ldlr-/-.Leiden mice. International Journal of Molecular Sciences 23 (18) , 10736. 10.3390/ijms231810736
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Carpanini, Sarah M., Torvell, Megan, Bevan, Ryan J. ORCID: https://orcid.org/0000-0002-2557-2887, Byrne, Robert A. J., Daskoulidou, Nikoleta, Saido, Takaomi C., Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421, Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490, Zelek, Wioleta M. and Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 2022. Terminal complement pathway activation drives synaptic Loss in Alzheimer’s disease models. Acta Neuropathologica Communications 10 , 99. 10.1186/s40478-022-01404-w
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Webberley, Thomas S., Masetti, Giulia, Bevan, Ryan J., Kerry-Smith, Joshua, Jack, Alison A., Michael, Daryn R., Thomas, Sophie, Glymenaki, Maria, Li, Jia, McDonald, Julie A. K., John, Daniel, Morgan, James E., Marchesi, Julian R. ORCID: https://orcid.org/0000-0002-7994-5239, Good, Mark A., Plummer, Sue F. and Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490 2022. The impact of probiotic supplementation on cognitive, pathological and metabolic markers in a transgenic mouse model of Alzheimer’s Disease. Frontiers in Neuroscience 16 , 843105. 10.3389/fnins.2022.843105
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Westacott, Laura J., Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Haan, Niels, Brain, Sophie A., Bush, Emma-Louise, Toneva, Margarita, Baloc, Andreea-Ingrid, Moon, Anna L. ORCID: https://orcid.org/0000-0002-6587-4425, Reddaway, Jack, Owen, Michael J. ORCID: https://orcid.org/0000-0003-4798-0862, Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009, Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Gray, William P. ORCID: https://orcid.org/0000-0001-7595-8887 and Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124 2022. Complement C3 and C3aR mediate different aspects of emotional behaviours; relevance to risk for psychiatric disorder. Brain, Behavior, and Immunity 99 , pp. 70-82. 10.1016/j.bbi.2021.09.005
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Baker, L.M., Webberley, T.S., Masetti, G., Hughes, T.R. ORCID: https://orcid.org/0000-0003-2348-3490, Marchesi, J.R., Jack, A.A., Joyce, T.S.C., Allen, M.D., Plummer, S.F., Michael, D.R., Ramanathan, G., Del Sol, R. and Facey, P.D. 2021. A genome guided evaluation of the Lab4 probiotic consortium. Genomics 113 (6) , pp. 4028-4038. 10.1016/j.ygeno.2021.08.007
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Westacott, Laura J., Haan, Niels, Evison, Claudia, Marei, Omar, Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009, Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490, Zaben, Malik ORCID: https://orcid.org/0000-0002-7446-4532, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124 and Gray, William P. ORCID: https://orcid.org/0000-0001-7595-8887 2021. Dissociable effects of complement C3 and C3aR on survival and morphology of adult born hippocampal neurons, pattern separation, and cognitive flexibility in male mice. Brain, Behavior, and Immunity 98 , pp. 136-150. 10.1016/j.bbi.2021.08.215
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Webberley, Thomas S., Masetti, Giulia, Baker, Laura M., Dally, Jordanna, Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490, Marchesi, Julian R., Jack, Alison A., Plummer, Sue F., Ramanathan, Guru, Facey, Paul D. and Michael, Daryn R. 2021. The impact of Lab4 probiotic supplementation in a 90-Day study in wistar rats. Frontiers in Nutrition 8 , 778289. 10.3389/fnut.2021.778289
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Al-Ahmadi, Wijdan, Webberley, Thomas S., Joseph, Alex, Harris, Ffion, Chan, Yee-Hung, Alotibi, Reem, Williams, Jessica O., Alahmadi, Alaa, Decker, Thomas, Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490 and Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578 2021. Pro-atherogenic actions of signal transducer and activator of transcription 1 serine 727 phosphorylation in LDL receptor deficient mice via modulation of plaque inflammation. FASEB Journal 35 (10) , e21892. 10.1096/fj.202100571RR
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Moss, Joe W. E. ORCID: https://orcid.org/0000-0002-1866-9752, Williams, Jessica O., Al-Ahmadi, Wijdan, O'Morain, Victoria, Chan, Yee-Hung, Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490, Menendez-Gonzalez, Juan B., Almotiri, Alhomidi, Plummer, Sue F., Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733, Michael, D. R. and Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578 2021. Protective effects of a unique combination of nutritionally active ingredients on risk factors and gene expression associated with atherosclerosis in C57BL/6J mice fed a high fat diet. Food and Function 12 (8) , pp. 3657-3671. 10.1039/D0FO02867C
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Mullish, Benjamin H., Marchesi, Julian R. ORCID: https://orcid.org/0000-0002-7994-5239, McDonald, Julie A. K., Pass, Daniel A. ORCID: https://orcid.org/0000-0003-2799-8432, Masetti, Giulia, Michael, Daryn R., Plummer, Sue, Jack, Alison A., Davies, Thomas S., Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490 and Wang, Duolao 2021. Probiotics reduce self-reported symptoms of upper respiratory tract infection in overweight and obese adults: should we be considering probiotics during viral pandemics? Gut Microbes 13 (1) , pp. 1-9. 10.1080/19490976.2021.1900997
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Bevan, Ryan J., Hughes, Tim R. ORCID: https://orcid.org/0000-0003-2348-3490, Williams, Pete A., Good, Mark A. ORCID: https://orcid.org/0000-0002-1824-1203, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Morgan, James E. ORCID: https://orcid.org/0000-0003-4075-7676 2020. Retinal ganglion cell degeneration correlates with hippocampal spine loss in experimental Alzheimer's disease. Acta Neuropathologica Communications 8 (1) , 216. 10.1186/s40478-020-01094-2
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Michael, D. R., Jack, A. A., Masetti, G., Davies, T. S., Loxley, K. E., Kerry-Smith, J., Plummer, J. F., Marchesi, J. R. ORCID: https://orcid.org/0000-0002-7994-5239, Mullish, B. H., McDonald, J. A. K., Hughes, T. R. ORCID: https://orcid.org/0000-0003-2348-3490, Wang, D., Garaiova, I., Paduchová, Z., Muchová, J., Good, M. A. ORCID: https://orcid.org/0000-0002-1824-1203 and Plummer, S. F. 2020. A randomised controlled study shows supplementation of overweight and obese adults with lactobacilli and bifidobacteria reduces bodyweight and improves well-being. Scientific Reports 10 (1) , -. 10.1038/s41598-020-60991-7
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Michael, D.R., Davies, T.S., Loxley, K.E., Allen, M.D., Good, M.A. ORCID: https://orcid.org/0000-0002-1824-1203, Hughes, T.R. ORCID: https://orcid.org/0000-0003-2348-3490 and Plummer, S.F. 2019. In vitro neuroprotective activities of two distinct probiotic consortia. Beneficial Microbes 10 (4) , pp. 437-447. 10.3920/BM2018.0105
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Boshra, Hani, Zelek, Wioleta M., Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490, Rodriguez de Cordoba, Santiago and Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 2018. Absence of CD59 in guinea pigs: Analysis of the Cavia porcellus genome suggests the evolution of a CD59 pseudogene. Journal of Immunology 200 (1) , pp. 327-335. 10.4049/jimmunol.1701238

Michael, D. R., Davies, T. S., Moss, J. W. E., Calvente, D. Lama, Ramji, D. P. ORCID: https://orcid.org/0000-0002-6419-5578, Marchesi, J. R. ORCID: https://orcid.org/0000-0002-7994-5239, Pechlivanis, A., Plummer, S. F. and Hughes, T. R. ORCID: https://orcid.org/0000-0003-2348-3490 2017. The anti-cholesterolaemic effect of a consortium of probiotics: An acute study in C57BL/6J mice. Scientific Reports 7 , 2883. 10.1038/s41598-017-02889-5
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Bergfeld, Arne, Dasari, Prasad, Werner, Sandra, Hughes, Timothy ORCID: https://orcid.org/0000-0003-2348-3490, Song, Wen-Chao, Hortschansky, Peter, Brakhage, Axel A., Hünig, Thomas, Zipfel, Peter F. and Beyersdorf, Niklas 2017. Direct binding of the pH-regulated protein 1 (Pra1) from Candida albicans inhibits cytokine secretion by mouse CD4+ T cells. Frontiers in Microbiology 8 10.3389/fmicb.2017.00844
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Granados-Durán, Pablo, López-Ávalos, María Dolores, Cifuentes, Manuel, Pérez-Martín, Margarita, Fernández-Arjona, María del Mar, Hughes, Timothy ORCID: https://orcid.org/0000-0003-2348-3490, Johnson, Krista, Morgan, Bryan ORCID: https://orcid.org/0000-0003-4075-7676, Fernández-Llebrez, Pedro and Grondona, Jesús M. 2017. Microbial neuraminidase induces a moderate and transient myelin vacuolation independent of complement system activation. Frontiers in Neurology 8 , 78. 10.3389/fneur.2017.00078
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Granados-Duran, Pablo, Lopez-Avalos, Maria Dolores, Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490, Johnson, Krista, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Tamburini, Paul P., Fernandez-Llebrez, Pedro and Grondona, Jesus M. 2016. Complement system activation contributes to the ependymal damage induced by microbial neuraminidase. Journal of Neuroinflammation 13 (115) 10.1186/s12974-016-0576-9
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Towner, Laurence D., Wheat, Richard A., Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490 and Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 2016. Complement membrane attack and tumorigenesis: a systems biology approach. Journal of Biological Chemistry 291 (29) , pp. 14927-14938. 10.1074/jbc.M115.708446
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Bloom, Anja C., Collins, Fraser L., van't Hof, Rob J., Ryan, Elizabeth S., Jones, Emma, Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Erlandsson, Malin, Bokarewa, Maria, Aeschlimann, Daniel ORCID: https://orcid.org/0000-0003-0930-7706, Evans, Bronwen A. J. ORCID: https://orcid.org/0000-0002-3082-1008 and Williams, Anwen S. ORCID: https://orcid.org/0000-0001-6118-020X 2016. Deletion of the membrane complement inhibitor CD59a drives age and gender-dependent alterations to bone phenotype in mice. Bone 84 , pp. 253-261. 10.1016/j.bone.2015.12.014
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Triantafilou, Martha ORCID: https://orcid.org/0000-0002-8489-2602, Hughes, Timothy ORCID: https://orcid.org/0000-0003-2348-3490, Morgan, Bryan ORCID: https://orcid.org/0000-0003-4075-7676 and Triantafilou, Kathy ORCID: https://orcid.org/0000-0002-7473-6278 2016. Complementing the inflammasome. Immunology 147 (2) , pp. 152-164. 10.1111/imm.12556

McCully, Michelle L., Collins, Paul J., Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Billen, Jaak, O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 and Moser, Bernhard ORCID: https://orcid.org/0000-0002-4354-4572 2015. Skin metabolites define a new paradigm in the localization of skin tropic memory T cells. Journal of Immunology 195 (1) , pp. 96-104. 10.4049/jimmunol.1402961
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Ramaglia, V., Jackson, S. J., Hughes, Timothy ORCID: https://orcid.org/0000-0003-2348-3490, Neal, James, Baker, D. and Morgan, Bryan ORCID: https://orcid.org/0000-0003-4075-7676 2015. Complement activation and expression during chronic relapsing experimental autoimmune encephalomyelitis in the Biozzi ABH mouse. Clinical & Experimental Immunology 180 (3) , pp. 432-441. 10.1111/cei.12595

Davies, T. S., Gallagher, H., Jaafar, F., Moss, J. W., Hughes, Timothy Rutland ORCID: https://orcid.org/0000-0003-2348-3490 and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2015. Interferon gamma signalling in atherosclerosis: pro-atherogenic actions and therapeutic approaches. Cardiology 131 , p. 292.
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Towner, Laurence, Hughes, Timothy ORCID: https://orcid.org/0000-0003-2348-3490 and Morgan, B. Paul 2014. Exploring the effects of non-lethal complement membrane attack on CT26 Colon Carcinoma cells using network analysis of differentially expressed genes. Molecular Immunology 61 (2) , pp. 245-246.

Davies, T. S., Li, N., McLaren, James ORCID: https://orcid.org/0000-0002-7021-5934, Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490 and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2014. Pro- therogenic actions of interferon-gamma on macrophages in atherosclerosis. Cardiology 128 (S1) , p. 278. 10.1159/000365062

Steiner, Tanja, Francescut, Lorenza, Byrne, Simon, Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490, Jayanthi, Archana, Guschina, Irina, Harwood, Adrian John ORCID: https://orcid.org/0000-0003-2377-2612, Cianflone, Katherine, Stover, Cordula and Francis, Sheila 2014. Protective role for properdin in progression of experimental murine atherosclerosis. PLoS ONE 9 (3) , e92404. 10.1371/journal.pone.0092404
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Triantafilou, K. ORCID: https://orcid.org/0000-0002-7473-6278, Hughes, T. R. ORCID: https://orcid.org/0000-0003-2348-3490, Triantafilou, M. ORCID: https://orcid.org/0000-0002-7473-6278 and Morgan, B. P. ORCID: https://orcid.org/0000-0003-4075-7676 2013. The complement membrane attack complex triggers intracellular Ca2+ fluxes leading to NLRP3 inflammasome activation. Journal of Cell Science 126 (13) , pp. 2903-2913. 10.1242/jcs.124388

Laudisi, F., Spreafico, R., Evrard, M., Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490, Mandriani, B., Kandasamy, M., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Sivasankar, B. and Mortellaro, A. 2013. Cutting edge: The NLRP3 inflammasome links complement-mediated inflammation and IL-1β release. The Journal of Immunology 191 (3) , pp. 1006-1010. 10.4049/jimmunol.1300489

Killick, R., Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Lovestone, S. 2013. Corrigendum to “Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH” [Neurosci. Lett. 533 (2013) 96–99] [Corrigendum]. Neuroscience Letters 545 , p. 144. 10.1016/j.neulet.2013.05.004

Killick, R., Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Lovestone, S. 2013. Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH. Neuroscience Letters 533 , pp. 96-99. 10.1016/j.neulet.2012.11.008

Kandasamy, Matheswaran, Ying, Poon C., Ho, Adrian W. S., Sumatoh, Hermi R., Schlitzer, Andreas, Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490, Kemeny, David M., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Ginhoux, Florent and Sivasankar, Baalasubramanian 2013. Complement mediated signaling on pulmonary CD103+ dendritic cells is critical for their migratory function in response to influenza infection. PLoS Pathogens 9 (1) , e1003115. 10.1371/journal.ppat.1003115
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Ramaglia, Valeria, Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490, Donev, Rossen Mintchev, Ruseva, Marieta Milkova, Wu, Xiaobo, Huitinga, Inge, Baas, Frank, Neal, James William and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2012. C3-dependent mechanism of microglial priming relevant to multiple sclerosis. Proceedings of the National Academy of Sciences 109 (3) , pp. 965-970. 10.1073/pnas.1111924109

Lewis, Ruth D., Perry, Mark J., Guschina, Irina, Jackson, Christopher L., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490 2011. CD55 deficiency protects against atherosclerosis in ApoE-deficient mice via C3a modulation of lipid metabolism. American Journal of Pathology 179 (4) , pp. 1601-1607. 10.1016/j.ajpath.2011.06.015

Lueck, K., Wasmuth, S., Williams, J., Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Lommatzsch, A., Greenwood, J., Moss, Sarah E. and Pauleikhoff, D. 2011. Sub-lytic C5b-9 induces functional changes in retinal pigment epithelial cells consistent with age-related macular degeneration. Eye 25 (8) , pp. 1074-1082. 10.1038/eye.2011.109

Copland, D. A., Hussain, K., Baalasubramanian, Sivasankar, Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Xu, H., Dick, A. D. and Nicholson, L. B. 2010. Systemic and local anti-C5 therapy reduces the disease severity in experimental autoimmune uveoretinitis. Clinical and Experimental Immunology 159 (3) , pp. 303-314. 10.1111/j.1365-2249.2009.04070.x

Gray, Lisa Clare, Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490 and Van Den Berg, Carmen Wilma 2010. Binding of human antigen R (HuR) to an AU-rich element (ARE) in the 3' untranslated region (3' UTR) reduces the expression of decay accelerating factor (DAF). Molecular Immunology 47 (16) , pp. 2545-2551. 10.1016/j.molimm.2010.07.002

Lewis, Ruth D., Jackson, Christopher L., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490 2010. The membrane attack complex of complement drives the progression of atherosclerosis in apolipoprotein E knockout mice. Molecular Immunology 47 (5) , pp. 1098-1105. 10.1016/j.molimm.2009.10.035

Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490, Ross, Kirsty S., Cowan, Graeme J. M., Baalasubramanian, Sivasank, Harris, Claire Louise, Mitchell, Timothy J. and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2009. Identification of the high affinity binding site in the Streptococcus intermedius toxin intermedilysin for its membrane receptor, the human complement regulator CD59. Molecular Immunology 46 (7) , pp. 1561-1567. 10.1016/j.molimm.2009.01.003

Ruseva, Marieta Milkova, Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490, Donev, Rossen Mintchev, Baalasubramanian, Sivasankar, Pickering, Matthew C., Wu, Xiaobo, Harris, Claire Louise and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2009. Crry deficiency in complement sufficient mice: C3 consumption occurs without associated renal injury. Molecular Immunology 46 (5) , pp. 803-811. 10.1016/j.molimm.2008.09.003

Donev, Rossen Mintchev, Gray, Lisa Clare, Baalasubramanian, Sivasankar, Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490, Van Den Berg, Carmen Wilma and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2008. Modulation of CD59 expression by restrictive silencer factor-derived peptides in cancer immunotherapy for neuroblastoma [RETRACTED]. Cancer Research 68 (14) , pp. 5979-5987. 10.1158/0008-5472.CAN-07-6828

Sivasankar, Baalasubramanian, Donev, Rossen Mintchev, Longhi, M. Paula, Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490, Davies, Ruth, Cole, Duncan Sean, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Marchbank, Kevin J. 2007. CD59a deficient mice display reduced B cell activity and antibody production in response to T-dependent antigens. Molecular Immunology 44 (11) , pp. 2978-2987. 10.1016/j.molimm.2006.12.025

Donev, Rossen Mintchev, Cole, Duncan Sean, Sivanaskar, Baalasubramanian, Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490 and Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 2006. p53 regulates cellular resistance to complement lysis through enhanced expression of CD59 [RETRACTED]. Cancer Research 66 (4) , pp. 2451-8. 10.1158/0008-5472.CAN-05-3191

Irvine, Scott A., Martin, John, Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490 and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2006. Lipoprotein lipase is expressed by glomerular mesangial cells. The International Journal of Biochemistry & Cell Biology 38 (1) , pp. 12-16. 10.1016/j.biocel.2005.07.008

Mead, James R., Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490, Irvine, Scott A., Singh, Nishi Nihar and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2003. Interferon-γ stimulates the expression of the inducible cAMP early repressor in macrophages through the activation of casein kinase 2: A Potentially novel pathway for interferon-γ-mediated inhibition of gene transcription. Journal of Biological Chemistry , pp. 17741-17751. 10.1074/jbc.M301602200

Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490, Tengku-Muhammad, T. S., Irvine, S. A. and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2002. A novel role of Sp1 and Sp3 in the interferon- -mediated suppression of macrophage lipoprotein lipase gene transcription. Journal of Biological Chemistry 277 (13) , pp. 11097-11106. 10.1074/jbc.M106774200

Kockar, Feray Tura, Foka, Pelagia, Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490, Kousteni, Stavroula and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2001. Analysis of the Xenopus laevis CCAAT-enhancer binding protein α gene promoter demonstrates species-specific differences in the mechanisms for both auto-activation and regulation by Sp1. Nucleic Acids Research 29 (2) , pp. 362-372. 10.1093/nar/29.2.362

Granger, Rachel L., Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490 and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2000. Gene, stimulus and cell-type specific regulation of activator protein-1 in mesangial cells by lipopolysaccharide and cytokines. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression 1492 (1) , pp. 100-107. 10.1016/S0167-4781(00)00089-0

Granger, Rachel L, Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490 and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2000. Stimulus- and cell-type-specific regulation of CCAAT-enhancer binding protein isoforms in glomerular mesangial cells by lipopolysaccharide and cytokines. Biochimica et Biophysica Acta - Molecular Basis of Disease 1501 (2-3) , pp. 171-179. 10.1016/S0925-4439(00)00016-8

This list was generated on Fri Nov 7 10:27:26 2025 GMT.


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