Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Browse by Current Cardiff authors

Number of items: 40.

Roberts, Luke D., Hornsby, Amanda K.E., Thomas, Alanna, Sassi, Martina, Kinzett, Aimee, Hsiao, Nathan, David, Bethan R., Good, Mark ORCID:, Wells, Timothy ORCID: and Davies, Jeffrey S. 2023. The 5:2 diet does not increase adult hippocampal neurogenesis or enhance spatial memory in mice. EMBO Reports 24 (12) , e57269. 10.15252/embr.202357269

Rees, Daniel, Beynon, Amy L., Lelos, Mariah J. ORCID:, Smith, Gaynor A. ORCID:, Roberts, Luke D., Phelps, Lyndsey, Dunnett, Stephen B. ORCID:, Morgan, Alwena H., Brown, Rowan M., Wells, Timothy ORCID: and Davies, Jefrey S. 2023. Acyl-ghrelin attenuates neurochemical and motor deficits in the 6-OHDA model of Parkinson’s Disease. Cellular and Molecular Neurobiology 43 , pp. 2377-2384. 10.1007/s10571-022-01282-9

Hornsby, Amanda K.E., Buntwal, Luke, Carisi, Maria Carla, Santos, Vanessa V., Johnston, Fionnuala, Roberts, Luke D., Sassi, Martina, Mequinion, Mathieu, Stark, Romana, Reichenbach, Alex, Lockie, Sarah H., Siervo, Mario, Howell, Owain, Morgan, Alwena H., Wells, Timothy ORCID:, Andrews, Zane B., Burn, David J. and Davies, Jeffrey S. 2020. Unacylated-ghrelin impairs hippocampal neurogenesis and memory in mice and is altered in Parkinson's dementia in humans. Cell Reports Medicine 1 (7) , 100120. 10.1016/j.xcrm.2020.100120

Tilston, Thomas W, Brown, Richard D, Wateridge, Matthew J, Arms-Williams, Bradley, Walker, Jamie J, Sun, Yuxiang and Wells, Timothy ORCID: 2019. A novel automated system yields reproducible temporal feeding patterns in laboratory rodents. Journal of Nutrition 149 (9) , pp. 1674-1684. 10.1093/jn/nxz116

Braxton, Thomas M., Sarpong, Dionne Ea, Dovey, Janine L, Guillou, Anne, Evans, Ba ORCID:, Castellano, Juan M., Keenan, Bethany E. ORCID:, Baraghithy, Saja, Evans, Sam L. ORCID:, Tena-Sempere, Manuel, Mollard, Patrice, Tam, Joseph and Wells, Timothy ORCID: 2019. Thermoneutrality improves skeletal impairment in adult Prader-Willi syndrome mice. Journal of Endocrinology 243 (3) , pp. 175-186. 10.1530/JOE-19-0279

Ratcliff, Michael, Rees, Daniel, McGrady, Scott, Buntwal, Luke, Hornsby, Amanda K. E., Bayliss, Jaqueline, Kent, Brianne A., Bussey, Timothy, Saksida, Lisa, Beynon, Amy L., Howell, Owain W., Morgan, Alwena H., Sun, Yuxiang, Andrews, Zane B., Wells, Timothy ORCID: and Davies, Jeffrey S. 2019. Calorie restriction activates new adult born olfactory-bulb neurones in a ghrelin-dependent manner but acyl-ghrelin does not enhance subventricular zone neurogenesis. Journal of Neuroendocrinology 31 (7) , -. 10.1111/jne.12755

Welden, Justin R., Zhang, Zhaiyi, Duncan, Marilyn J., Falaleeva, Marina, Wells, Timothy ORCID: and Stamm, Stefan 2018. The posterior pituitary expresses the serotonin receptor 2C. Neuroscience Letters 684 , pp. 132-139. 10.1016/j.neulet.2018.06.051

Hopkins, Anna L., Nelson, Timothy A. S., Guschina, Irina A., Parsons, Lydia C., Lewis, Charlotte L., Brown, Richard C., Christian, Helen C., Davies, Jeffrey S. and Wells, Timothy ORCID: 2017. Unacylated ghrelin promotes adipogenesis in rodent bone marrow via ghrelin O-acyl transferase and GHS-R1a activity: evidence for target-cell-induced acylation. Scientific Reports 7 , 45541. 10.1038/srep45541

Golding, David M., Rees, Daniel J., Davies, Jennifer R., Relkovic, Dinko, Furby, Hannah V. ORCID:, Guschina, Irina A., Hopkins, Anna L., Davies, Jeffrey S., Resnick, James L., Isles, Anthony R. ORCID: and Wells, Timothy ORCID: 2017. Paradoxical leanness in the imprinting-centre deletion mouse model for Prader–Willi syndrome. Journal of Endocrinology 232 (1) , pp. 123-135. 10.1530/JOE-16-0367

Navein, Alice E., Cooke, Esther J., Davies, Jennifer R., Smith, Terence G., Wells, Lois H. M. ORCID:, Ohazama, Atsushi, Healy, Christopher, Sharpe, Paul T., Evans, Sam L. ORCID:, Evans, Bronwen A. J. ORCID:, Votruba, Marcela ORCID: and Wells, Timothy ORCID: 2016. Disrupted mitochondrial function in the Opa3L122P mouse model for Costeff Syndrome impairs skeletal integrity. Human Molecular Genetics 25 (12) , pp. 2404-2416. 10.1093/hmg/ddw107

Hornsby, Amanda K. E., Redhead, Yushi T., Rees, Daniel J., Ratcliff, Michael S. G., Reichenbach, Alex, Wells, Timothy ORCID:, Francis, Lewis, Amstalden, Katia, Andrews, Zane B. and Davies, Jeffrey S. 2016. Short-term calorie restriction enhances adult hippocampal neurogenesis and remote fear memory in a Ghsr-dependent manner. Psychoneuroendocrinology 63 , pp. 198-207. 10.1016/j.psyneuen.2015.09.023

Davies, Jennifer R. ORCID:, Humby, Trevor ORCID:, Dwyer, Dominic M. ORCID:, Garfield, Alastair S., Furby, Hannah ORCID:, Wilkinson, Lawrence Stephen ORCID:, Wells, Timothy ORCID: and Isles, Anthony Roger ORCID: 2015. Calorie seeking, but not hedonic response, contributes to hyperphagia in a mouse model for Prader-Willi syndrome. European Journal of Neuroscience 42 (4) , pp. 2105-2113. 10.1111/ejn.12972

Evans, Bronwen Alice James ORCID:, James, T. W., James, K., Cox, A., Farr, L., Paisey, Stephen James ORCID:, Dempster, D. W., Stone, M. D., Griffiths, P. A., Hugtenburg, R. P., Brady, Sir M. and Wells, Timothy ORCID: 2014. Preclinical assessment of a new magnetic resonance-based technique for determining bone quality by characterization of trabecular microarchitecture. Calcified Tissue International 95 (6) , pp. 506-520. 10.1007/s00223-014-9922-z

Man, Pui-Sin, Wells, Timothy ORCID: and Carter, David Allan 2014. Cellular distribution of Egr1 transcription in the male rat pituitary gland. Journal of Molecular Endocrinology 53 (2) , pp. 271-280. 10.1530/JME-14-0158

El-Kasti, Muna Mustafa, Wells, Timothy ORCID: and Carter, David Allan 2012. A novel long-range enhancer regulates postnatal expression of Zeb2: implications for Mowat-Wilson syndrome phenotypes. Human Molecular Genetics 21 (26) , pp. 5429-5442. 10.1093/hmg/dds389

Wells, Timothy ORCID:, Davies, Jennifer Rhian, Guschina, Irina, Ball, Daniel, Davies, Jeffrey Stephens, Davies, Vanessa J., Evans, Bronwen Alice James ORCID: and Votruba, Marcela ORCID: 2012. Opa3, a novel regulator of mitochondrial function, controls thermogenesis and abdominal fat mass in a mouse model for Costeff syndrome. Human Molecular Genetics 21 (22) , pp. 4836-4844. 10.1093/hmg/dds315

Glad, C., Kitchen, E., Russ, G., Harris, S., Davies, J., Gevers, E., Gabrielsson, B. and Wells, Timothy ORCID: 2011. Reverse feeding suppresses the activity of the GH axis in rats and induces a preobesogenic state. Endocrinology 152 (3) , pp. 869-882. 10.1210/en.2010-0713

Evans, Bronwen Alice James ORCID:, Bullen, Melanie Jean, Kench, Rebecca Carol, Fox, Rebecca E., Morgan, Liam David ORCID:, Stevenson, Amy Elizabeth, Gevers, Evelien F., Perry, Mark J. and Wells, Timothy ORCID: 2011. The influence of leptin on trabecular architecture and marrow adiposity in GH-deficient rats. Journal of Endocrinology 208 (1) , pp. 69-79. 10.1677/JOE-10-0178

Carter, David Allan, Rough, Kirsty and Wells, Timothy ORCID: 2011. Transcription mapping of embryonic rat brain reveals EGR-1 induction in SOX2+ neural progenitor cells. Frontiers in Molecular Neuroscience 4 10.3389/fnmol.2011.00006

Davies, Jeffrey Stephens, Kotokorpi, Pia, Eccles, Sinan R., Barnes, Sarah K., Tokarczuk, Pawel Franciszek, Allen, Sophie Katharine, Whitworth, Hilary S., Guschina, Irina, Evans, Bronwen Alice James ORCID:, Mode, Agneta, Zigman, Jeffrey M. and Wells, Timothy ORCID: 2009. Ghrelin induces abdominal obesity via GHS-R-dependent lipid retention. Molecular Endocrinology 23 (6) , pp. 914-924. 10.1210/me.2008-0432

Stevenson, A. E., Evans, Bronwen Alice James ORCID:, Gevers, E. F., Elford, Carole, McLeod, Robert William J., Perry, M. J., El-Kasti, M. M., Coschigano, K. T., Kopchick, J. J., Evans, Samuel Lewin ORCID: and Wells, Timothy ORCID: 2009. Does adiposity status influence femoral cortical strength in rodent models of growth hormone deficiency? American Journal of Physiology - Endocrinology and Metabolism 296 (1) , E147-E156. 10.1152/ajpendo.90689.2008

Wells, Timothy ORCID: 2009. Ghrelin - Defender of fat. Progress in Lipid Research 48 (5) , pp. 257-274. 10.1016/j.plipres.2009.04.002

El-Kasti, Muna Mustafa, Christian, H. C., Huerta-Ocampo, I., Stolbrink, M., Gill, S., Houston, P. A., Davies, J. S., Chilcott, J., Hill, N., Matthews, D. R., Carter, David Allan and Wells, Timothy ORCID: 2008. The pregnancy-induced increase in baseline circulating growth hormone in rats is not induced by ghrelin. Journal of Neuroendocrinology 20 (3) , pp. 309-322. 10.1111/j.1365-2826.2008.01650.x

Davies, J. S., Kotokorpi, P., Lindahl, U., Oscarsson, J., Wells, Timothy ORCID: and Mode, A. 2008. Effects of the synthetic liver X receptor agonist T0901317 on the growth hormone and thyroid hormone axes in male rats. Endocrine 33 (2) , pp. 196-204. 10.1007/s12020-008-9067-9

Mansergh, Fiona Catherine, Wells, Timothy ORCID:, Elford, Carole, Evans, Samuel Lewin ORCID:, Evans, Martin John, Perry, Mark J. and Evans, Bronwen Alice James ORCID: 2007. Osteopenia in Sparc (osteonectin) deficient mice: characterization of phenotypic determinants of femoral strength and changes in gene expression. Physiological genomics 32 (1) , pp. 64-73. 10.1152/physiolgenomics.00151.2007

Man, Pui Sin, Wells, Timothy ORCID: and Carter, David Allan 2007. Egr-1-d2EGFP transgenic rats identify transient populations of neurons and glial cells during postnatal brain development. Gene Expression Patterns 7 (8) , pp. 872-883. 10.1016/j.modgep.2007.06.006

Davies, Jeffrey Stephens, Gevers, Evelien F., Stevenson, Amy Elizabeth, Coschigano, Karen T., El-Kasti, Muna Mustafa, Bull, Melanie J., Elford, Carole., Evans, Bronwen Alice James ORCID:, Kopchick, John J. and Wells, Timothy ORCID: 2007. Adiposity profile in the dwarf (dw/dw) rat: an unusually lean model of profound growth hormone deficiency. American Journal of Physiology - Endocrinology and Metabolism 292 (5) , E1483-E1494. 10.1152/ajpendo.00417.2006

Holter, J. L., Davies, J. S., Man, P. S., Wells, Timothy ORCID: and Carter, David Allan 2007. Transgenic delivery and detection of GFP in neuropeptide neurons. Neuropeptide Techniques, Neuromethods, vol. 39. Springer, pp. 31-44. (10.1007/978-1-60327-099-1_5)

Humphries, Ann L., Wells, Timothy ORCID:, Baler, Ruben, Klein, David C. and Carter, David Allan 2007. Rodent Aanat: intronic E-box sequences control tissue specificity but not rhythmic expression in the pineal gland. Molecular and Cellular Endocrinology 270 (1-2) , pp. 43-49. 10.1016/j.mce.2007.02.003

Davies, Jeffrey S., Thompson, N. M., Christian, H. C., Pinilla, L., Ebling, F. J. P., Tena-Sempere, M. and Wells, Timothy ORCID: 2006. Hypothalamic expression of human growth hormone induces post-pubertal hypergonadotrophism in male transgenic growth retarded rats. Journal of Neuroendocrinology 18 (10) , pp. 719-731. 10.1111/j.1365-2826.2006.01467.x

Martini, A. C., Fernández-Fernández, R., Tovar, S., Navarro, V. M., Vigo, E., Vazquez, Marisol, Davies, J. S., Thompson, N. M., Aguilar, E., Pinilla, L., Wells, Timothy ORCID:, Dieguez, C and Tena-Sempere, M. 2006. Comparative analysis of the effects of ghrelin and unacylated ghrelin on luteinizing hormone secretion in male rats. Endocrinology 147 (5) , pp. 2374-2382. 10.1210/en.2005-1422

Davies, Jeffrey Stephens, Holter, J. L., Knight, D., Beaucourt, S. M., Murphy, D., Carter, David A. and Wells, Timothy ORCID: 2004. Manipulating sorting signals to generate co-expression of somatostatin and eGFP in the regulated secretory pathway from a monocistronic construct. Journal of Molecular Endocrinology 33 (2) , pp. 523-532. 10.1677/jme.1.01578

Davies, Jeffrey S., Carter, David Allan and Wells, Timothy ORCID: 2004. Photic stimulation inhibits growth hormone secretion in rats: A hypothalamic mechanism for transient entrainment. Endocrinology 145 (6) , 2950. 10.1210/en.2003-1236

Evans, Bronwen A. J. ORCID:, Warner, Justin T., Elford, Carole, Evans, Samuel Lewin ORCID:, Laib, L., Bains, R. K., Gregory, John Welbourn ORCID: and Wells, Tim ORCID: 2003. Morphological determinants of femoral strength in growth hormone-deficient transgenic growth-retarded (Tgr) rats. Journal of Bone and Mineral Research 18 (7) , pp. 1308-1316. 10.1359/jbmr.2003.18.7.1308

Thompson, Nichola M., Davies, Jeffrey Stephens, Mode, Agneta, Houston, Pamela A. and Wells, Timothy ORCID: 2003. Pattern-dependent suppression of growth hormone (GH) pulsatility by ghrelin and GH-releasing peptide-6 in moderately GH-deficient rats. Endocrinology 144 (11) , pp. 4859-4867. 10.1210/en.2003-0423

Slade, J. P., Man, Pui Sin, Wells, Timothy ORCID: and Carter, David Allan 2002. Stimulus-specific induction of an Egr-I transgene in a rat brain. Neuroreport -Oxford- 13 (5) , pp. 671-674.

Smith, Martyn, Burke, Zoe, Humphries, Ann, Wells, Timothy ORCID:, Klein, David, Carter, David Allan and Baler, Ruben 2001. Tissue-specific transgenic knockdown of Fos-related antigen 2 (Fra-2) expression mediated by dominant negative Fra-2. Molecular and Cellular Biology 21 (11) , pp. 3704-3713. 10.1128/MCB.21.11.3704-3713.2001

Wells, Timothy ORCID: and Carter, David Allan 2001. Genetic engineering of neural function in transgenic rodents: towards a comprehensive strategy? Journal of Neuroscience Methods 108 (2) , pp. 111-130. 10.1016/S0165-0270(01)00391-0

Wells, Timothy ORCID: and Houston, P. A. 2001. Skeletal growth acceleration with growth hormone secretagogues in transgenic growth retarded rats: pattern-dependent effects and mechanisms of desensitization. Journal of Neuroendocrinology 13 (6) , pp. 496-504. 10.1046/j.1365-2826.2001.00661.x

Warner, Justin T., Wells, Timothy ORCID:, Elford, Carole, Evans, Bronwen Alice James ORCID:, Evans, Samuel Lewin ORCID: and Gregory, John Welbourn ORCID: 2000. Undermineralisation and reduced bone strength in growth hormone (GH) deficient transgenic (Tgr) rats. Journal of Bone and Mineral Research (JBMR) 15 (6) , p. 1219.

This list was generated on Sat Jun 22 05:41:45 2024 BST.