Browse by Current Cardiff authors

Zelek, Wioleta M., Bevan, Ryan J. ORCID: https://orcid.org/0000-0002-2557-2887, Nimo, Jacqui M., Dewilde, Maarten, De Strooper, Bart and Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 2025. Targeting novel anti‐complement drugs to the brain reduces complement activation and synapse loss, and improves cognition in a mouse model of dementia. Alzheimer's & Dementia: The Journal of the Alzheimer's Association 20 (S6) 10.1002/alz.090708

Zelek, Wioleta M., Bevan, Ryan J. ORCID: https://orcid.org/0000-0002-2557-2887, Nimmo, Jacqui, Dewilde, Maarten, De Strooper, Bart and Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 2024. Brain-penetrant complement inhibition mitigates neurodegeneration in an Alzheimer's disease mouse model. Brain 10.1093/brain/awae278

Zelek, Wioleta M., Bevan, Ryan J. ORCID: https://orcid.org/0000-0002-2557-2887 and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2024. Targeting terminal pathway reduces brain complement activation, amyloid load and synapse loss, and improves cognition in a mouse model of dementia. Brain, Behavior, and Immunity 118 , pp. 355-363. 10.1016/j.bbi.2024.03.017

Baillie, Kirsten, Davies, Helen E., Keat, Samuel B. K., Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Miners, Kelly L., Jones, Samantha A., Mellou, Ermioni, Toonen, Erik J. M., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Zelek, Wioleta M. 2024. Complement dysregulation is a prevalent and therapeutically amenable feature of long COVID. Med 5 (3) , pp. 239-253. 10.1016/j.medj.2024.01.011

Daskoulidou, Nikoleta, Carpanini, Sarah, Zelek, Wioleta and Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 2024. Involvement of complement in Alzheimer's Disease: From genetics through pathology to therapeutic strategies. Ellenbroek, Bart A., Barnes, Thomas R. E., Andersen, Susan L., Paulus, Martin P. and Olivier, Jocelien, eds. Current Topics in Behavioral Neurosciences, Springer, Berlin, Heidelberg, pp. 1-22. (10.1007/7854_2024_524)

Kamegai, Naoki, Kim, Hangsoo, Suzuki, Yasuhiro, Fukui, Sosuke, Kojima, Hiroshi, Maruyama, Shoichi, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Zelek, Wioleta Milena and Mizuno, Masashi 2023. Complement terminal pathway inhibition reduces peritoneal injuries in a rat peritonitis model. Clinical & Experimental Immunology 214 (2) , pp. 209-218. 10.1093/cei/uxad088

Karbian, Netanel, Eshed-Eisenbach, Yael, Zeibak, Marian, Tabib, Adi, Sukhanov, Natasha, Vainshtein, Anya, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Fellig, Yakov, Peles, Elior and Mevorach, Dror 2023. Complement-membrane regulatory proteins are absent from the nodes of Ranvier in the peripheral nervous system. Journal of Neuroinflammation 20 (1) , 245. 10.1186/s12974-023-02920-9

Daskoulidou, Nikoleta, Shaw, Bethany, Torvell, Megan, Watkins, Lewis, Cope, Emma L., Carpanini, Sarah M., Allen, Nicholas D. ORCID: https://orcid.org/0000-0003-4009-186X and Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 2023. Complement receptor 1 is expressed on brain cells and in the human brain. Glia 71 (6) , pp. 1522-1535. 10.1002/glia.24355

Veteleanu, Aurora, Pape, Sarah, Davies, Kate ORCID: https://orcid.org/0000-0002-9807-1231, Kodosaki, Eleftheria, Hye, Abdul, Zelek, Wioleta M., Strydom, Andre and Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 2023. Complement dysregulation and Alzheimer's disease in Down syndrome. Alzheimer's & Dementia: The Journal of the Alzheimer's Association 19 (4) , pp. 1383-1392. 10.1002/alz.12799

Siggins, Matthew K., Davies, Kate ORCID: https://orcid.org/0000-0002-9807-1231, Fellows, Rosie, Thwaites, Ryan S., Baillie, J. Kenneth, Semple, Malcolm G., Openshaw, Peter J.M., Zelek, Wioleta, Harris, Claire L. and Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 2023. Alternative pathway dysregulation in tissues drives sustained complement activation and predicts outcome across the disease course in COVID-19. Immunology 168 (3) , pp. 473-492. 10.1111/imm.13585

Stevenson-Hoare, Joshua, Heslegrave, Amanda, Leonenko, Ganna ORCID: https://orcid.org/0000-0001-8025-661X, Fathalla, Dina, Bellou, Eftychia, Luckcuck, Lauren, Marshall, Rachel, Sims, Rebecca ORCID: https://orcid.org/0000-0002-3885-1199, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Hardy, John, de Strooper, Bart, Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259, Zetterberg, Henrik and Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 2023. Plasma biomarkers and genetics in the diagnosis and prediction of Alzheimer's disease. Brain 146 (2) , pp. 690-699. 10.1093/brain/awac128

Lekova, Eleonora, Zelek, Wioleta M., Gower, David, Spitzfaden, Claus, Osuch, Isabelle H., John-Morris, Elen, Stach, Lasse, Gormley, Darren, Sanderson, Andrew, Bridges, Angela, Wear, Elizabeth R., Petit-Frere, Sebastien, Burden, Michael N., Priest, Richard, Wattam, Trevor, Kitchen, Semra J., Feeney, Maria, Davis, Susannah, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Nichols, Eva-Maria 2022. Discovery of functionally distinct anti-C7 monoclonal antibodies and stratification of anti-nicotinic AChR positive Myasthenia Gravis patients. Frontiers in Immunology 13 , 968206. 10.3389/fimmu.2022.968206

Zelek, Wioleta M. and Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 2022. Targeting complement in neurodegeneration: challenges, risks, and strategies. Trends in Pharmacological Sciences 43 (8) , pp. 615-628. 10.1016/j.tips.2022.02.006

Carpanini, Sarah M., Torvell, Megan, Bevan, Ryan J. ORCID: https://orcid.org/0000-0002-2557-2887, Byrne, Robert A. J., Daskoulidou, Nikoleta, Saido, Takaomi C., Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421, Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490, Zelek, Wioleta M. and Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 2022. Terminal complement pathway activation drives synaptic Loss in Alzheimer’s disease models. Acta Neuropathologica Communications 10 , 99. 10.1186/s40478-022-01404-w

Banda, Nirmal K., Deane, Kevin D., Bemis, Elizabeth A., Strickland, Colin, Seifert, Jennifer, Jordan, Kimberly, Goldman, Katriona, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Moreland, Larry W., Lewis, Myles J., Pitzalis, Costantino and Holers, V. Michael 2022. Analysis of complement gene expression, clinical associations, and biodistribution of complement proteins in the synovium of early rheumatoid arthritis patients reveals unique pathophysiologic features. Journal of Immunology 208 (11) , pp. 2482-2496. 10.4049/jimmunol.2101170

Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153, Sabberwal, Pragati, Williamson, James C., Greenwood, Edward J.D., Crozier, Thomas WM, Zelek, Wioleta, Seow, Jeffrey, Graham, Carl, Huettner, Isabella, Edgeworth, Jonathan D., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Morgan, Paul B. ORCID: https://orcid.org/0000-0003-4075-7676, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Eberl, Matthias ORCID: https://orcid.org/0000-0002-9390-5348, Humphreys, Ian R. ORCID: https://orcid.org/0000-0002-9512-5337, Merrick, Blair, Doores, Katie, Wilson, Sam J., Lehner, Paul J., Wang, Eddie C.Y. ORCID: https://orcid.org/0000-0002-2243-4964 and Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182 2022. SARS-CoV-2 host-shutoff impacts innate NK cell functions, but antibody-dependent NK activity is strongly activated through non-spike antibodies. eLife 11 10.7554/eLife.74489

Lewis, Lisa A, Gulati, Sunita, Zelek, Wioleta M., Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Song, Wen-Chao, Zheng, Bo, Nowak, Nancy, DeOliveira, Rosane B., Sanchez, Bryan, DeSouza Silva, Leandro, Schuurman, Janine, Beurskens, Frank, Ram, Sanjay and Rice, Peter A 2022. Efficacy of an experimental gonococcal lipooligosaccharide mimitope vaccine requires terminal complement. The Journal of Infectious Diseases 225 (10) , 1861–1864. 10.1093/infdis/jiab630

Gytz Olesen, Heidi, Michailidou, Iliana, Zelek, Wioleta M., Vreijling, Jeroen, Ruizendaal, Patrick, de Klein, Ferry, Marquart, J. Arnoud, Kuipers, Thomas B., Mei, Hailiang, Zhang, Yuchun, Ahasan, Muhammad, Johnson, Krista K., Wang, Yi, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, van Dijk, Marcus, Fluiter, Kees, Andersen, Gregers Rom and Baas, Frank 2022. Development, characterization, and in vivo validation of a humanized C6 monoclonal antibody that Inhibits the membrane attack complex. Journal of Innate Immunity 10.1159/000524587

Kolka, Cathryn M., Webster, Julie, Lepletier, Ailin, Winterford, Clay, Brown, Ian, Richards, Renee S., Zelek, Wioleta M., Cao, Yilang, Khamis, Ramlah, Shanmugasundaram, Karthik B., Wuethrich, Alain, Trau, Matt, Brosda, Sandra, Barbour, Andrew, Shah, Alok K., Eslick, Guy D., Clemons, Nicholas J., Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Hill, Michelle M. 2022. C5b-9 membrane attack complex formation and extracellular vesicle shedding in Barrett's esophagus and esophageal adenocarcinoma. Frontiers in Immunology 13 , 842023. 10.3389/fimmu.2022.842023

Scurr, Martin ORCID: https://orcid.org/0000-0002-4120-0688, Zelek, Wioleta, Lippiatt, George, Somerville, Michelle, Burnell, Stephanie, Capitani, Lorenzo, Davies, Kate, Lawton, Helen, Tozer, Thomas, Rees, Tara, Roberts, Kerry, Evans, Mererid, Jackson, Amanda, Young, Charlotte, Fairclough, Lucy, Tighe, Paddy, Wills, Mark, Westwell, Andrew ORCID: https://orcid.org/0000-0002-5166-9236, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567 2022. Whole blood-based measurement of SARS-CoV-2-specific T cells reveals asymptomatic infection and vaccine immunogenicity in healthy subjects and patients with solid organ cancers. Immunology 165 (2) , pp. 250-259. 10.1111/imm.13433

Cooze, B.J., Dickerson, M., Loganathan, R., Watkins, L.M., Grounds, E., Pearson, B.R., Bevan, R.J., Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Magliozzi, R., Reynolds, R., Neal, J.W. and Howell, O.W. 2022. The association between neurodegeneration and local complement activation in the thalamus to progressive multiple sclerosis outcome. Brain Pathology 32 , e13054. 10.1111/bpa.13054

Westacott, Laura J., Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Haan, Niels, Brain, Sophie A., Bush, Emma-Louise, Toneva, Margarita, Baloc, Andreea-Ingrid, Moon, Anna L. ORCID: https://orcid.org/0000-0002-6587-4425, Reddaway, Jack, Owen, Michael J. ORCID: https://orcid.org/0000-0003-4798-0862, Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009, Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Gray, William P. ORCID: https://orcid.org/0000-0001-7595-8887 and Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124 2022. Complement C3 and C3aR mediate different aspects of emotional behaviours; relevance to risk for psychiatric disorder. Brain, Behavior, and Immunity 99 , pp. 70-82. 10.1016/j.bbi.2021.09.005

Torvell, Megan, Carpanini, Sarah M., Daskoulidou, Nikoleta, Byrne, Robert A. J., Sims, Rebecca ORCID: https://orcid.org/0000-0002-3885-1199 and Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 2021. Genetic insights into the impact of complement in Alzheimer's disease. Genes 12 (12) , 1990. 10.3390/genes12121990

Chakraborty, Mallinath, Rodrigues, Patrícia R. S. ORCID: https://orcid.org/0000-0003-0768-0013, Watkins, W. John ORCID: https://orcid.org/0000-0003-3262-6588, Hayward, Angela, Sharma, Alok, Hayward, Rachel, Smit, Elisa, Jones, Rebekka, Goel, Nitin, Asokkumar, Amar, Calvert, Jennifer, Odd, David, Morris, Ian, Doherty, Cora, Elliott, Sian, Strang, Angela, Andrews, Robert, Zaher, Summia, Sharma, Simran, Bell, Sarah, Oruganti, Siva, Smith, Claire, Orme, Judith, Edkins, Sarah ORCID: https://orcid.org/0000-0003-0717-1972, Craigon, Marie, White, Daniel, Dantoft, Widad, Davies, Luke C., Moet, Linda, McLaren, James E. ORCID: https://orcid.org/0000-0002-7021-5934, Clarkstone, Samantha, Watson, Gareth L., Hood, Kerenza ORCID: https://orcid.org/0000-0002-5268-8631, Kotecha, Sailesh ORCID: https://orcid.org/0000-0003-3535-7627, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2021. nSeP: immune and metabolic biomarkers for early detection of neonatal sepsis-protocol for a prospective multicohort study. BMJ Open 11 (12) , e050100. 10.1136/bmjopen-2021-050100

Westacott, Laura J., Haan, Niels, Evison, Claudia, Marei, Omar, Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009, Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490, Zaben, Malik ORCID: https://orcid.org/0000-0002-7446-4532, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124 and Gray, William P. ORCID: https://orcid.org/0000-0001-7595-8887 2021. Dissociable effects of complement C3 and C3aR on survival and morphology of adult born hippocampal neurons, pattern separation, and cognitive flexibility in male mice. Brain, Behavior, and Immunity 98 , pp. 136-150. 10.1016/j.bbi.2021.08.215

Wong, Edwin, Marchbank, Kevin, Lomax-Browne, Hannah, Pappworth, Isabel, Denton, Harriet, Cooke, Katie, Ward, Sophie, McLoughlin, Amy-Claire, Richardson, Grant, Wilson, Valerie, Harris, Claire, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Hakobyan, Svetlana, McAlinden, Paul, Gale, Daniel, Maxwell, Heather, Christian, Martin, Malcomson, Roger, Goodship, Timothy, Marks, Stephen, Pickering, Matthew, Kavanagh, David, Cook, H. Terence and Johnson, Sally 2021. C3 Glomerulopathy and related disorders in children. Clinical Journal of the American Society of Nephrology 16 (11) , pp. 1639-1651. 10.2215/CJN.00320121

Byrne, Robert A. J., Torvell, Megan, Daskoulidou, Nikoleta, Fathalla, Dina, Kokkali, Eirini, Carpanini, Sarah M. and Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 2021. Novel monoclonal antibodies against mouse C1q: characterisation and development of a quantitative ELISA for mouse C1q. Molecular Neurobiology 58 (9) , pp. 4323-4336. 10.1007/s12035-021-02419-5

MacKenzie, Georgina, Subramaniam, Sumithra, Caldwell, Lindsey J., Fitzgerald, Denise, Harrison, Neil A. ORCID: https://orcid.org/0000-0002-9584-3769, Hong, Soyon, Irani, Sarosh R., Khandaker, Golam M., Liston, Adrian, Miron, Veronique E., Mondelli, Valeria, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Pariante, Carmine, Shah, Divya K., Taams, Leonie S., Teeling, Jessica L. and Upthegrove, Rachel 2021. Research priorities for neuroimmunology: identifying the key research questions to be addressed by 2030. Wellcome Open Research 6 , 194. 10.12688/wellcomeopenres.16997.1

Mc Mahon, O., Hallam, T. M., Patel, S., Harris, C. L., Menny, A., Zelek, W. M., Widjajahakim, R., Java, A., Cox, T., Tzoumas, N., Steel, D. H. W., Shuttleworth, V. G., Smith-Jackson, K., Brocklebank, V., Griffiths, H., Cree, A. J., Atkinson, J. P., Lotery, A. J., Bubeck, D., Morgan, B. P. ORCID: https://orcid.org/0000-0003-4075-7676, Marchbank, K. J., Seddon, J. M. and Kavanagh, D. 2021. The rare C9 P167S risk variant for age-related macular degeneration increases polymerization of the terminal component of the complement cascade. Human Molecular Genetics 30 (13) , pp. 1188-1199. 10.1093/hmg/ddab086

Webster, Julie A., Wuethrich, Alain, Shanmugasundaram, Karthik B., Richards, Renee S., Zelek, Wioleta M., Shah, Alok K., Gordon, Louisa G., Kendall, Bradley J., Hartel, Gunter, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Trau, Matt and Hill, Michelle M. 2021. Development of EndoScreen chip, a microfluidic pre-endoscopy triage test for esophageal adenocarcinoma. Cancers 13 (12) , 2865. 10.3390/cancers13122865

Carpanini, Sarah M., Harwood, Janet C., Baker, Emily, Torvell, Megan, Sims, Rebecca ORCID: https://orcid.org/0000-0002-3885-1199, Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259 and Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 2021. The impact of complement genes on the risk of late-onset Alzheimer's disease. Genes 12 (3) , 443. 10.3390/genes12030443

Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Gommerman, Jennifer L. and Ramaglia, Valeria 2021. An “outside-in” and “inside-out” consideration of complement in the multiple sclerosis brain: lessons from development and neurodegenerative diseases. Frontiers in Cellular Neuroscience 14 , 600656. 10.3389/fncel.2020.600656

Murrell, Isa, Forde, Donall, Zelek, Wioleta, Tyson, Linda, Chichester, Lisa, Palmer, Nicki, Jones, Rachel, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Moore, Catherine 2021. Temporal development and neutralising potential of antibodies against SARS-CoV-2 in hospitalised COVID-19 patients: An observational cohort study. PLoS ONE 16 (1) , e0245382. 10.1371/journal.pone.0245382

Rodrigues, Patrícia R.S. ORCID: https://orcid.org/0000-0003-0768-0013, Picco, Noemi, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Ghazal, Peter ORCID: https://orcid.org/0000-0003-0035-2228 2021. Sepsis target validation for repurposing and combining complement and immune checkpoint inhibition therapeutics. Expert Opinion on Drug Discovery 16 (5) , pp. 537-551. 10.1080/17460441.2021.1851186

Buckland, Matthew S., Galloway, James B., Fhogartaigh, Caoimhe Nic, Meredith, Luke, Provine, Nicholas M., Bloor, Stuart, Ogbe, Ane, Zelek, Wioleta M., Smielewska, Anna, Yakovleva, Anna, Mann, Tiffeney, Bergamaschi, Laura, Turner, Lorinda, Mescia, Frederica, Toonen, Erik J. M., Hackstein, Carl-Philipp, Akther, Hossain Delowar, Vieira, Vinicius Adriano, Ceron-Gutierrez, Lourdes, Periselneris, Jimstan, Kiani-Alikhan, Sorena, Grigoriadou, Sofia, Vaghela, Devan, Lear, Sara E., Török, M. Estée, Hamilton, William L., Stockton, Joanne, Quick, Josh, Nelson, Peter, Hunter, Michael, Coulter, Tanya I., Devlin, Lisa, Bradley, John R., Smith, Kenneth G. C., Ouwehand, Willem H., Estcourt, Lise, Harvala, Heli, Roberts, David J., Wilkinson, Ian B., Screaton, Nick, Loman, Nicholas, Doffinger, Rainer, Lyons, Paul A., Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Goodfellow, Ian G., Klenerman, Paul, Lehner, Paul J., Matheson, Nicholas J. and Thaventhiran, James E. D. 2020. Treatment of COVID-19 with remdesivir in the absence of humoral immunity: a case report. Nature Communications 11 (1) , 6385. 10.1038/s41467-020-19761-2

Zelek, Wioleta M. and Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 2020. Monoclonal antibodies capable of inhibiting complement downstream of C5 in multiple species. Frontiers in Immunology 11 (11) , 612402. 10.3389/fimmu.2020.612402

Bevan, Ryan J., Hughes, Tim R. ORCID: https://orcid.org/0000-0003-2348-3490, Williams, Pete A., Good, Mark A. ORCID: https://orcid.org/0000-0002-1824-1203, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Morgan, James E. ORCID: https://orcid.org/0000-0003-4075-7676 2020. Retinal ganglion cell degeneration correlates with hippocampal spine loss in experimental Alzheimer's disease. Acta Neuropathologica Communications 8 (1) , 216. 10.1186/s40478-020-01094-2

Zelek, Wioleta Milena, Fathalla, Dina, Morgan, Angharad ORCID: https://orcid.org/0000-0003-4075-7676, Touchard, Samuel, Loveless, Samantha ORCID: https://orcid.org/0000-0002-5124-4115, Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634, Robertson, Neil P. ORCID: https://orcid.org/0000-0002-5409-4909 and Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 2020. Cerebrospinal fluid complement system biomarkers in demyelinating disease. Multiple Sclerosis 26 (14) , pp. 1929-1937. 10.1177/1352458519887905

O'Connor, Daryl B., Aggleton, John P. ORCID: https://orcid.org/0000-0002-5573-1308, Chakarabati, Bhismadev, Cooper, Cary L., Creswell, Cathy, Dunsmuir, Sandra, Fiske, Susan T., Gathercole, Susan, Gough, Brendan, Ireland, Jane L., Jones, Marc V., Jowett, Adam, Kagan, Carolyn, Karanika-Murray, Maria, Kaye, Linda K., Kumari, Veena, Lewandowsky, Stephan, Lightman, Stafford, Malpass, Debra, Meins, Elizabeth, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Morrison Coulthard, Lisa J., Reicher, Stephen D., Schacter, Daniel L, Sherman, Susan M., Simms, Victoria, Williams, Antony, Wykes, Til and Armitage, Christopher J. 2020. Research priorities for the COVID-19 pandemic and beyond: a call to action for psychological science. British Journal of Psychology 111 (4) , pp. 603-629. 10.1111/bjop.12468

Zelek, Wioleta M., Cole, Jade, Ponsford, Mark J., Harrison, Richard A., Schroeder, Ben E., Webb, Nicholas, Jolles, Stephen, Fegan, Christopher ORCID: https://orcid.org/0000-0001-9685-0621, Morgan, Matt ORCID: https://orcid.org/0000-0003-4075-7676, Wise, Matt P. and Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 2020. Complement inhibition with the C5 blocker LFG316 in severe COVID-19. American Journal of Respiratory and Critical Care Medicine 202 (9) , pp. 1304-1308. 10.1164/rccm.202007-2778LE

Zelek, Wioleta M., Menzies, Georgina E. ORCID: https://orcid.org/0000-0002-6600-6507, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Stockinger, Brigitta and Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 2020. Characterising the original anti-C5 function-blocking antibody, BB5.1, for species specificity, mode of action and interactions with C5. Immunology 161 (2) , pp. 103-113. 10.1111/imm.13228

Shi, Liu, Winchester, Laura M., Liu, Benjamine Y., Killick, Richard, Ribe, Elena M., Westwood, Sarah, Baird, Alison L., Buckley, Noel J., Hong, Shengjun, Dobricic, Valerija, Kilpert, Fabian, Franke, Andre, Kiddle, Steven, Sattlecker, Martina, Dobson, Richard, Cuadrado, Antonio, Hye, Abdul, Ashton, Nicholas J., Morgan, Angharad R., Bos, Isabelle, Vos, Stephanie J.B., ten Kate, Mara, Scheltens, Philip, Vandenberghe, Rik, Gabel, Silvy, Meersmans, Karen, Engelborghs, Sebastiaan, De Roeck, Ellen E., Sleegers, Kristel, Frisoni, Giovanni B., Blin, Olivier, Richardson, Jill C., Bordet, Régis, Molinuevo, José L., Rami, Lorena, Wallin, Anders, Kettunen, Petronella, Tsolaki, Magda, Verhey, Frans, Lleó, Alberto, Alcolea, Daniel, Popp, Julius, Peyratout, Gwendoline, Martinez-Lage, Pablo, Tainta, Mikel, Johannsen, Peter, Teunissen, Charlotte E., Freund-Levi, Yvonne, Frölich, Lutz, Legido-Quigley, Cristina, Barkhof, Frederik, Blennow, Kaj, Rasmussen, Katrine Laura, Nordestgaard, Børge Grønne, Frikke-Schmidt, Ruth, Nielsen, Sune Fallgaard, Soininen, Hilkka, Vellas, Bruno, Kloszewska, Iwona, Mecocci, Patrizia, Zetterberg, Henrik, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Streffer, Johannes, Visser, Pieter Jelle, Bertram, Lars, Nevado-Holgado, Alejo J. and Lovestone, Simon 2020. Dickkopf-1 overexpression in vitro nominates candidate blood biomarkers relating to Alzheimer's disease pathology. Journal of Alzheimer's Disease 77 (3) , pp. 1353-1368. 10.3233/JAD-200208

Jackson, Harriet M., Foley, Kate E., O'Rourke, Rita, Stearns, Timothy M., Fathalla, Dina, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Howell, Gareth R. 2020. A novel mouse model expressing human forms for complement receptors CR1 and CR2. BMC Genetics 21 (1) , 101. 10.1186/s12863-020-00893-9

van Dijk, Bart J., Meijers, Joost C.M., Kloek, Anne T., Knaup, Veronique L., Rinkel, Gabriel J.E., Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, van der Kamp, Marije J., Osuka, Koji, Aronica, Eleonora, Ruigrok, Ynte M., van de Beek, Diederik, Brouwer, Matthijs, Pekna, Marcela, Hol, Elly M. and Vergouwen, Mervyn D.I. 2020. Complement C5 contributes to brain injury after subarachnoid hemorrhage. Translational Stroke Research 11 , pp. 678-688. 10.1007/s12975-019-00757-0

Mondelli, Valeria, Di Forti, Marta, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Murray, Robin M., Pariante, Carmine M. and Dazzan, Paola 2020. Baseline high levels of complement component 4 predict worse clinical outcome at 1-year follow-up in first-episode psychosis. Brain, Behavior, and Immunity 88 , pp. 913-915. 10.1016/j.bbi.2020.01.014

Altmann, Tom, Torvell, Megan, Owens, Stephen, Mitra, Dipayan, Sheerin, Neil S., Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Kavanagh, David and Forsyth, Rob 2020. Complement factor I deficiency: a potentially treatable cause of fulminant cerebral inflammation. Neurology, Neuroimmunology and Neuroinflammation 7 (3) , e689. 10.1212/NXI.0000000000000689

Ghias, Mondana H., Hyde, Michael J., Tomalin, Lewis E., Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Alavi, Afsaneh, Lowes, Michelle A. and Piguet, Vincent 2020. Role of the complement pathway in inflammatory skin diseases: a focus on hidradenitis suppurativa. Journal of Investigative Dermatology 140 (3) , 531-536.e1. 10.1016/j.jid.2019.09.009

Westwood, Sarah, Baird, Alison L., Anand, Sneha N., Nevado-Holgado, Alejo J., Kormilitzin, Andrey, Shi, Liu, Hye, Abdul, Ashton, Nicholas J., Morgan, Angharad, Bos, Isabelle, Vos, Stephanie J. B., Baker, Susan, Buckley, Noel J., Ten Kate, Mara, Scheltens, Philip, Teunissen, Charlotte E., Vandenberghe, Rik, Gabel, Silvy, Meersmans, Karen, Engelborghs, Sebastiaan, De Roeck, Ellen E., Sleegers, Kristel, Frisoni, Giovanni B., Blin, Olivier, Richardson, Jill C., Bordet, Régis, Molinuevo, José L., Rami, Lorena, Wallin, Anders, Kettunen, Petronella, Tsolaki, Magda, Verhey, Frans, Lléo, Alberto, Sala, Isabel, Popp, Julius, Peyratout, Gwendoline, Martinez-Lage, Pablo, Tainta, Mikel, Johannsen, Peter, Freund-Levi, Yvonne, Frölich, Lutz, Dobricic, Valerija, Legido-Quigley, Cristina, Bertram, Lars, Barkhof, Frederik, Zetterberg, Henrik, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Streffer, Johannes, Visser, Pieter Jelle and Lovestone, Simon 2020. Validation of plasma proteomic biomarkers relating to brain amyloid burden in the EMIF-Alzheimer's disease multimodal biomarker discovery cohort. Journal of Alzheimer's Disease 74 (1) , pp. 213-225. 10.3233/JAD-190434

Cipriani, Valentina, Lorés-Motta, Laura, He, Fan, Fathalla, Dina, Tilakaratna, Viranga, McHarg, Selina, Bayatti, Nadhim, Acar, İlhan E, Hoyng, Carel B, Fauser, Sascha, Moore, Anthony T, Yates, John RW, de Jong, Eiko K, Morgan, B Paul ORCID: https://orcid.org/0000-0003-4075-7676, den Hollander, Anneke I, Bishop, Paul N and Clark, Simon J 2020. Increased circulating levels of Factor H-Related Protein 4 are strongly associated with age-related macular degeneration. Nature Communications 11 , 778. 10.1038/s41467-020-14499-3

Shi, Liu, Westwood, Sarah, Baird, Alison L., Winchester, Laura, Dobricic, Valerija, Kilpert, Fabian, Hong, Shengjun, Franke, Andre, Hye, Abdul, Ashton, Nicholas J., Morgan, Angharad R., Bos, Isabelle, Vos, Stephanie J. B., Buckley, Noel J., Kate, Mara ten, Scheltens, Philip, Vandenberghe, Rik, Gabel, Silvy, Meersmans, Karen, Engelborghs, Sebastiaan, De Roeck, Ellen E., Sleegers, Kristel, Frisoni, Giovanni B., Blin, Olivier, Richardson, Jill C., Bordet, Régis, Molinuevo, José L., Rami, Lorena, Wallin, Anders, Kettunen, Petronella, Tsolaki, Magda, Verhey, Frans, Lleó, Alberto, Alcolea, Daniel, Popp, Julius, Peyratout, Gwendoline, Martinez-Lage, Pablo, Tainta, Mikel, Johannsen, Peter, Teunissen, Charlotte E., Freund-Levi, Yvonne, Frölich, Lutz, Legido-Quigley, Cristina, Barkhof, Frederik, Blennow, Kaj, Zetterberg, Henrik, Baker, Susan, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Streffer, Johannes, Visser, Pieter Jelle, Bertram, Lars, Lovestone, Simon and Nevado-Holgado, Alejo J. 2019. Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay. Alzheimer's and Dementia 15 (11) , pp. 1478-1488. 10.1016/j.jalz.2019.06.4951

Mancuso, Renzo, Fryatt, Gemma, Cleal, Madeleine, Obst, Juliane, Pipi, Elena, Monzón-Sandoval, Jimena, Ribe, Elena, Winchester, Laura, Webber, Caleb ORCID: https://orcid.org/0000-0001-8063-7674, Nevado, Alejo, Jacobs, Tom, Austin, Nigel, Theunis, Clara, Grauwen, Karolien, Ruiz, Eva Daniela, Mudher, Amrit, Vicente-Rodriguez, Marta, Parker, Christine A., Simmons, Camilla, Cash, Diana, Richardson, Jill, Bullmore, Edward T., Bhatti, Junaid, Chamberlain, Samuel J., Correia, Marta M., Crofts, Anna L., Dickinson, Amber, Foster, Andrew C., Kitzbichler, Manfred G., Knight, Clare, Lynall, Mary-Ellen, Maurice, Christina, O'Donnell, Ciara, Pointon, Linda J., Hyslop, Peter St. George, Turner, Lorinda, Vertes, Petra, Widmer, Barry, Williams, Guy B., Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Leckey, Claire A., Morgan, Angharad R. ORCID: https://orcid.org/0000-0003-4075-7676, O'Hagan, Caroline, Touchard, Samuel, Cavanagh, Jonathan, Deith, Catherine, Farmer, Scott, McClean, John, McColl, Alison, McPherson, Andrew, Scouller, Paul, Sutherland, Murray, Boddeke, H. W. G. M. (Erik), Richardson, Jill C., Khan, Shahid, Murphy, Phil, Parker, Christine A., Patel, Jai, Jones, Declan, de Boer, Peter, Kemp, John, Drevets, Wayne C., Nye, Jeffrey S., Wittenberg, Gayle, Isaac, John, Bhattacharya, Anindya, Carruthers, Nick, Kolb, Hartmuth, Pariante, Carmine M., Turkheimer, Federico, Barker, Gareth J., Byrom, Heidi, Cash, Diana, Cattaneo, Annamaria, Gee, Antony, Hastings, Caitlin, Mariani, Nicole, McLaughlin, Anna, Mondelli, Valeria, Nettis, Maria, Nikkheslat, Naghmeh, Randall, Karen, Sheridan, Hannah, Simmons, Camilla, Singh, Nisha, VAn Loo, Victoria, Vicente-Rodriguez, Marta, Wood, Tobias C, Worrell, Courtney, Zajkowska, Zuzanna, Plath, Niels, Egebjerg, Jan, Eriksson, Hans, Gastambide, Francois, Adams, Karen Husted, Jeggo, Ross, Thomsen, Christian, Pederson, Jan Torleif, Campbell, Brian, Möller, Thomas, Nelson, Bob, Zorn, Stevin, O'Connor, Jason, Attenburrow, Mary Jane, Baird, Alison, Benjamin, Jithen, Clare, Stuart, Cowen, Philip, Huang, I-Shu (Dante), Hurley, Samuel, Jones, Helen, Lovestone, Simon, Mada, Francisca, Nevado-Holgado, Alejo, Oladejo, Akintayo, Ribe, Elena, Smith, Katy, Vyas, Anviti, Hughes, Zoe, Balice-Gordon, Rita, Duerr, James, Piro, Justin R, Sporn, Jonathan, Perry (PI), V Hugh, Cleal, Madeleine, Fryatt, Gemma, Gomez-Nicola, Diego, Mancuso, Renzo, Reynolds, Richard, Harrison, Neil A. ORCID: https://orcid.org/0000-0002-9584-3769, Cercignani, Mara ORCID: https://orcid.org/0000-0002-4550-2456, Clarke, Charlotte L, Hoskins, Elizabeth, Kohn, Charmaine, Murray, Rosemary, Wilcock, Lauren, Wlazly, Dominika, Mount, Howard, Jones, Declan N. C., Lovestone, Simon, Gomez-Nicola, Diego and Perry, V. Hugh 2019. CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice. Brain 142 (10) , pp. 3243-3264. 10.1093/brain/awz241

Zelek, Wioleta M., Xie, Long, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Harris, Claire L. 2019. Compendium of current complement therapeutics. Molecular Immunology 114 , pp. 341-352. 10.1016/j.molimm.2019.07.030

Mastellos, Dimitrios C., Blom, Anna M., Connolly, E. Sander, Daha, Mohamed R., Geisbrecht, Brian V., Ghebrehiwet, Berhane, Gros, Piet, Hajishengallis, George, Holers, V. Michael, Huber-Lang, Markus, Kinoshita, Taroh, Mollnes, Tom E., Montgomery, Robert A., Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Nilsson, Bo, Pio, Ruben, Ricklin, Daniel, Risitano, Antonio M., Taylor, Ronald P., Mantovani, Alberto, Ioannidis, John P. A. and Lambris, John D. 2019. 'Stealth' corporate innovation: an emerging threat for therapeutic drug development. Nature Immunology 20 (11) , pp. 1409-1413. 10.1038/s41590-019-0503-1

Zelek, Wioleta M., Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421 and Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 2019. Development and characterisation of novel anti-C5 monoclonal antibodies capable of inhibiting complement in multiple species. Immunology 157 (4) , pp. 283-295. 10.1111/imm.13083

Yang, Jack, Ramirez Moral, Ivan, van 't Veer, Cornelis, de Vos, Alex F., de Beer, Regina, Roelofs, Joris J. T. H., Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 and van der Poll, Tom 2019. Complement factor C5 inhibition reduces type 2 responses without affecting group 2 innate lymphoid cells in a house dust mite induced murine asthma model. Respiratory Research 20 (1) , -. 10.1186/s12931-019-1136-5

Baker, Emily, Sims, Rebecca ORCID: https://orcid.org/0000-0002-3885-1199, Leonenko, Ganna ORCID: https://orcid.org/0000-0001-8025-661X, Frizzati, Aura ORCID: https://orcid.org/0000-0002-7002-6180, Harwood, Janet, Grozeva, Detelina ORCID: https://orcid.org/0000-0003-3239-8415, Morgan, Kevin ORCID: https://orcid.org/0000-0003-4075-7676, Passmore, Peter, Holmes, Clives, Powell, John, Brayne, Carol, Gill, Michael, Mead, Simon, Bossu, Paola, Spalletta, Gianfranco, Goate, Alison, Crunchaga, Carlos, Maier, Wolfgang, Heun, Reinhard, Jessen, Frank, Peters, Oliver, Dichgans, Martin, Frolich, Lutz, Ramirez, Alfredo, Jones, Lesley ORCID: https://orcid.org/0000-0002-3007-4612, Hardy, John, Ivanov, Dobril ORCID: https://orcid.org/0000-0001-6271-6301, Hill, Matthew ORCID: https://orcid.org/0000-0001-6776-8709, Holmans, Peter ORCID: https://orcid.org/0000-0003-0870-9412, Allen, Nicholas ORCID: https://orcid.org/0000-0003-4009-186X, Morgan, Paul ORCID: https://orcid.org/0000-0003-4075-7676, Seshadri, Sudha, Schellenberg, Gerard, Amouvel, Philippe, Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259 and Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483 2019. Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer’s disease. PLoS ONE 14 (7) , e0218111. 10.1371/journal.pone.0218111

Morgan, Angharad R., Touchard, Samuel, Leckey, Claire, O'Hagan, Caroline, Nevado-Holgado, Alejo J., Barkhof, Frederik, Bertram, Lars, Blin, Olivier, Bos, Isabelle, Dobricic, Valerija, Engelborghs, Sebastiaan, Frisoni, Giovanni, Frölich, Lutz, Gabel, Silvey, Johannsen, Peter, Kettunen, Petronella, Koszewska, Iwona, Legido-Quigley, Cristina, Lleó, Alberto, Martinez-Lage, Pablo, Mecocci, Patrizia, Meersmans, Karen, Molinuevo, José Luis, Peyratout, Gwendoline, Popp, Julius, Richardson, Jill, Sala, Isabel, Scheltens, Philip, Streffer, Johannes, Soininen, Hikka, Tainta-Cuezva, Mikel, Teunissen, Charlotte, Tsolaki, Magda, Vandenberghe, Rik, Visser, Pieter Jelle, Vos, Stephanie, Wahlund, Lars-Olof, Wallin, Anders, Westwood, Sarah, Zetterberg, Henrik, Lovestone, Simon, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Bullmore, Edward T., Bhatti, Junaid, Chamberlain, Samuel J., Correia, Marta M., Crofts, Anna L., Dickinson, Amber, Foster, Andrew C., Kitzbichler, Manfred G., Knight, Clare, Lynall, Mary-Ellen, Maurice, Christina, O'Donnell, Ciara, Pointon, Linda J., St George Hyslop, Peter, Turner, Lorinda, Vertes, Petra, Widmer, Barry, Williams, Guy B., Cavanagh, Jonathan, Deith, Catherine, Farmer, Scott, McClean, John, McColl, Alison, McPherson, Andrew, Scouller, Paul, Sutherland, Murray, Boddeke, H.W.G.M., Richardson, Jill C., Khan, Shahid, Murphy, Phil, Parker, Christine A., Patel, Jai, Jones, Declan, de Boer, Peter, Kemp, John, Drevets, Wayne C., Nye, Jeffrey S., Wittenberg, Gayle, Isaac, John, Bhattacharya, Anindya, Carruthers, Nick, Kolb, Hartmuth, Pariante, Carmine M., Turkheimer, Federico, Barker, Gareth J., Byrom, Heidi, Cash, Diana, Cattaneo, Annamaria, Gee, Antony, Hastings, Caitlin, Mariani, Nicole, McLaughlin, Anna, Mondelli, Valeria, Nettis, Maria, Nikkheslat, Naghmeh, Randall, Karen, Sheridan, Hannah, Simmons, Camilla, Singh, Nisha, Van Loo, Victoria, Vicente-Rodriguez, Marta, Wood, Tobias C., Worrell, Courtney, Zajkowska, Zuzanna, Plath, Niels, Egebjerg, Jan, Eriksson, Hans, Gastambide, Francois, Adams, Karen Husted, Jeggo, Ross, Thomsen, Christian, Pederson, Jan Torleif, Campbell, Brian, Möller, Thomas, Nelson, Bob, Zorn, Stevin, O'Connor, Jason, Attenburrow, Mary Jane, Baird, Alison, Benjamin, Jithen, Clare, Stuart, Cowen, Philip, Huang, I-Shu (Dante), Hurley, Samuel, Jones, Helen, Lovestone, Simon, Mada, Francisca, Nevado-Holgado, Alejo, Oladejo, Akintayo, Ribe, Elena, Smith, Katy, Vyas, Anviti, Hughes, Zoe, Balice-Gordon, Rita, Duerr, James, Piro, Justin R., Sporn, Jonathan, Perry, V. Hugh, Cleal, Madeleine, Fryatt, Gemma, Gomez-Nicola, Diego, Mancuso, Renzo, Reynolds, Richard, Harrison, Neil A. ORCID: https://orcid.org/0000-0002-9584-3769, Cercignani, Mara ORCID: https://orcid.org/0000-0002-4550-2456, Clarke, Charlotte L., Hoskins, Elizabeth, Kohn, Charmaine, Murray, Rosemary, Wilcock, Lauren, Wlazly, Dominika and Mount, Howard 2019. Inflammatory biomarkers in Alzheimer's disease plasma. Alzheimer's & Dementia 15 (6) , pp. 776-787. 10.1016/j.jalz.2019.03.007

Zelek, Wioleta M., Watkins, Lewis M., Howell, Owain W., Evans, Rhian, Loveless, Sam ORCID: https://orcid.org/0000-0002-5124-4115, Robertson, Neil P. ORCID: https://orcid.org/0000-0002-5409-4909, Beenes, Marijke, Willems, Loek, Brandwijk, Ricardo and Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 2019. Measurement of soluble CD59 in CSF in demyelinating disease: Evidence for an intrathecal source of soluble CD59. Multiple Sclerosis 25 (4) , pp. 523-531. 10.1177/1352458518758927

Goutaudier, Valentin, Perrochia, Hélène, Mucha, Simon, Bonnet, Marie, Delmas, Sylvie, Garo, Florian, Garrigue, Valérie, Lepreux, Sébastien, Pernin, Vincent, Serre, Jean-Emmanuel, Szwarc, Ilan, Merville, Pierre, Ramounau-Pigot, Annie, René, Céline, Visentin, Jonathan, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Frémeaux-Bacchi, Véronique, Mourad, Georges, Couzi, Lionel and Le Quintrec, Moglie 2019. C5b9 deposition in glomerular capillaries is associated with poor kidney allograft survival in antibody-mediated rejection. Frontiers in Immunology 10 , -. 10.3389/fimmu.2019.00235

Carpanini, Sarah M., Torvell, Megan and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2019. Therapeutic inhibition of the complement system in diseases of the central nervous system. Frontiers in Immunology 10 , -. 10.3389/fimmu.2019.00362

Kopczynska, Maja, Zelek, Wioleta, Touchard, Samuel, Gaughran, Fiona, Di Forti, Marta, Mondelli, Valeria, Murray, Robin, O'Donovan, Michael ORCID: https://orcid.org/0000-0001-7073-2379 and Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 2019. Complement system biomarkers in first episode psychosis. Schizophrenia Research 204 , pp. 16-22. 10.1016/j.schres.2017.12.012

Karbian, Netanel, Eshed-Eisenbach, Yael, Tabib, Adi, Hoizman, Hila, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Schueler-Furman, Ora, Peles, Elior and Mevorach, Dror 2018. Molecular pathogenesis of human CD59 deficiency. Neurology Genetics 4 (6) , e280. 10.1212/NXG.0000000000000280

Menny, Anaïs, Serna, Marina, Boyd, Courtney M., Gardner, Scott, Joseph, Agnel Praveen, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Topf, Maya, Brooks, Nicholas J. and Bubeck, Doryen 2018. CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers. Nature Communications 9 , 5316. 10.1038/s41467-018-07653-5

Zelek, Wioleta M., Harris, Claire L. and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2018. Extracting the barbs from complement assays: Identification and optimisation of a safe substitute for traditional buffers. Immunobiology 223 (12) , pp. 744-749. 10.1016/j.imbio.2018.07.016

Griffiths, Mark R., Botto, Marina, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Neal, James W. and Gasque, Philippe 2018. CD93 regulates central nervous system inflammation in two mouse models of autoimmune encephalomyelitis. Immunology 155 (3) , pp. 346-355. 10.1111/imm.12974

Zelek, Wioleta M., Stott, Matthew, Walters, David, Harris, Claire L. and Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 2018. Characterising a pH-switch anti-C5 antibody as a tool for human and mouse complement C5 purification and cross-species inhibition of classical and reactive lysis. Immunology 155 (3) , pp. 396-403. 10.1111/imm.12982

Kopczynska, Maja, Zelek, Wioleta, Vespa, Simone, Touchard, Samuel, Wardle, Mark, Loveless, Samantha ORCID: https://orcid.org/0000-0002-5124-4115, Thomas, Rhys H., Hamandi, Khalid and Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 2018. Complement system biomarkers in epilepsy. Seizure - European Journal of Epilepsy 60 , pp. 1-7. 10.1016/j.seizure.2018.05.016

Loveless, Sam ORCID: https://orcid.org/0000-0002-5124-4115, Neal, James W., Howell, Owain W., Harding, Katharine E., Sarkies, Patrick, Evans, Rhian, Bevan, Ryan J., Hakobyan, Svetlana, Harris, Claire L., Robertson, Neil P. ORCID: https://orcid.org/0000-0002-5409-4909 and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2018. Tissue microarray methodology identifies complement pathway activation and dysregulation in progressive multiple sclerosis. Brain Pathology 28 (4) , pp. 507-520. 10.1111/bpa.12546

Michailidou, Iliana, Jongejan, Aldo, Vreijling, Jeroen P., Georgakopoulou, Theodosia, de Wissel, Marit B., Wolterman, Ruud A., Ruizendaal, Patrick, Klar-Mohamad, Ngaisah, Grootemaat, Anita E., Picavet, Daisy I., Kumar, Vinod, van Kooten, Cees, Woodruff, Trent M., Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, van der Wel, Nicole N., Ramaglia, Valeria, Fluiter, Kees and Baas, Frank 2018. Systemic inhibition of the membrane attack complex impedes neuroinflammation in chronic relapsing experimental autoimmune encephalomyelitis. Acta Neuropathologica Communications 6 (1) , 36. 10.1186/s40478-018-0536-y

Mihai, Sidonia, Hirose, Misa, Wang, Yi, Thurman, Joshua M., Holers, V. Michael, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Köhl, Jörg, Zillikens, Detlef, Ludwig, Ralf J. and Nimmerjahn, Falk 2018. Specific inhibition of complement activation significantly ameliorates autoimmune blistering disease in mice. Frontiers in Immunology 9 , 535. 10.3389/fimmu.2018.00535

Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2018. Complement in the pathogenesis of Alzheimer's disease. Seminars in Immunopathology 40 (1) , pp. 113-124. 10.1007/s00281-017-0662-9

Boshra, Hani, Zelek, Wioleta M., Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490, Rodriguez de Cordoba, Santiago and Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 2018. Absence of CD59 in guinea pigs: Analysis of the Cavia porcellus genome suggests the evolution of a CD59 pseudogene. Journal of Immunology 200 (1) , pp. 327-335. 10.4049/jimmunol.1701238

Morgan, Angharad, O'Hagan, Caroline, Touchard, Samuel, Lovestone, Simon and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2017. Effects of freezer storage time on levels of complement biomarkers. BMC Research Notes 10 (1) , 559. 10.1186/s13104-017-2885-1

Stott, Matthew, van den Berg, Carmen, Forton, Julian ORCID: https://orcid.org/0000-0002-0580-0432, Monk, Peter, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 and McGreal, Eamon 2017. Post-translational modification of complement anaphylatoxins during chronic neutrophilic inflammation. Molecular Immunology 89 , p. 167. 10.1016/j.molimm.2017.06.141

Taylor, Ronald P., Lindorfer, Margaret A., Cook, Erika M., Beurskens, Frank J., Schuurman, Janine, Parren, Paul W.H.I., Zent, Clive S., VanDerMeid, Karl R., Burack, Richard, Mizuno, Masashi and Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 2017. Hexamerization-enhanced CD20 antibody mediates complement-dependent cytotoxicity in serum genetically deficient in C9. Clinical Immunology 181 , pp. 24-28. 10.1016/j.clim.2017.05.016

Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Boyd, Courtney and Bubeck, Doryen 2017. Molecular cell biology of complement membrane attack. Seminars in Cell and Developmental Biology

Hakobyan, Svetlana, Luppe, Sebastian, Evans, David R. S., Harding, Katharine, Loveless, Samantha ORCID: https://orcid.org/0000-0002-5124-4115, Robertson, Neil P. ORCID: https://orcid.org/0000-0002-5409-4909 and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2017. Plasma complement biomarkers distinguish multiple sclerosis and neuromyelitis optica spectrum disorder. Multiple Sclerosis Journal 23 (7) , pp. 946-955. 10.1177/1352458516669002

Granados-Durán, Pablo, López-Ávalos, María Dolores, Cifuentes, Manuel, Pérez-Martín, Margarita, Fernández-Arjona, María del Mar, Hughes, Timothy ORCID: https://orcid.org/0000-0003-2348-3490, Johnson, Krista, Morgan, Bryan ORCID: https://orcid.org/0000-0003-4075-7676, Fernández-Llebrez, Pedro and Grondona, Jesús M. 2017. Microbial neuraminidase induces a moderate and transient myelin vacuolation independent of complement system activation. Frontiers in Neurology 8 , 78. 10.3389/fneur.2017.00078

Morgan, Angharad, Touchard, Samuel, O'Hagan, Caroline, Sims, Rebecca ORCID: https://orcid.org/0000-0002-3885-1199, Majounie, Elisa ORCID: https://orcid.org/0000-0003-2800-1091, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Jones, Lesley ORCID: https://orcid.org/0000-0002-3007-4612, Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259 and Morgan, Bryan ORCID: https://orcid.org/0000-0003-4075-7676 2017. The correlation between inflammatory biomarkers and polygenic risk score in Alzheimer's Disease. Journal of Alzheimer's Disease 56 (1) , pp. 25-36. 10.3233/JAD-160889

Stover, Cordula M., Mizuno, Masashi, Suzuki, Yasuhiro, Higashide, Keiko, Sei, Yumi, Iguchi, Daiki, Sakata, Fumiko, Horie, Masanobu, Maruyama, Shoichi, Matsuo, Seiichi, Morgan, Bryan ORCID: https://orcid.org/0000-0003-4075-7676 and Ito, Yasuhiko 2017. High levels of soluble C5b-9 complex in dialysis fluid may predict poor prognosis in peritonitis in peritoneal dialysis patients. PLoS ONE 12 (1) , e0169111. 10.1371/journal.pone.0169111

Granados-Duran, Pablo, Lopez-Avalos, Maria Dolores, Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490, Johnson, Krista, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Tamburini, Paul P., Fernandez-Llebrez, Pedro and Grondona, Jesus M. 2016. Complement system activation contributes to the ependymal damage induced by microbial neuraminidase. Journal of Neuroinflammation 13 (115) 10.1186/s12974-016-0576-9

Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Walters, David, Serna, Marina and Bubeck, Doryen 2016. Terminal complexes of the complement system: new structural insights and their relevance to function. Immunological Reviews 274 (1) , pp. 141-151. 10.1111/imr.12461

Hakobyan, Svetlana, Harding, Katharine, Aiyaz, Mohammed, Hye, Abdul, Dobson, Richard, Baird, Alison, Liu, Benjamine, Harris, Claire, Lovestone, Simon and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2016. Complement biomarkers as predictors of disease progression in Alzheimer's disease. Journal of Alzheimer's Disease 54 (2) , pp. 707-716. 10.3233/JAD-160420

Heurich-Sevcenco, M. ORCID: https://orcid.org/0000-0003-0105-2702, Preston, R.J.S., O'Donnell, V. B. ORCID: https://orcid.org/0000-0003-4089-8460, Morgan, B. P. ORCID: https://orcid.org/0000-0003-4075-7676 and Collins, P. W. ORCID: https://orcid.org/0000-0002-6410-1324 2016. Thrombomodulin enhances complement regulation through strong affinity interactions with factor H and C3b-Factor H complex. Thrombosis Research 145 , pp. 84-92. 10.1016/j.thromres.2016.07.017

Towner, Laurence D., Wheat, Richard A., Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490 and Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 2016. Complement membrane attack and tumorigenesis: a systems biology approach. Journal of Biological Chemistry 291 (29) , pp. 14927-14938. 10.1074/jbc.M115.708446

Challis, Rachel C., Araujo, Geisilaine S. R., Wong, Edwin K. S., Anderson, Holly E., Awan, Atif, Dorman, Anthony M., Waldron, Mary, Wilson, Valerie, Brocklebank, Vicky, Strain, Lisa, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Harris, Claire L., Marchbank, Kevin J., Goodship, Timothy H. J. and Kavanagh, David 2016. A de novo deletion in the regulators of complement activation cluster producing a hybrid complement factor H/complement factor H-related 3 gene in atypical hemolytic uremic syndrome. Journal of the American Society of Nephrology 27 (6) , pp. 1617-1624. 10.1681/ASN.2015010100

Watkins, Lewis M., Neal, James W., Loveless, Samantha ORCID: https://orcid.org/0000-0002-5124-4115, Michailidou, Iliana, Ramaglia, Valeria, Rees, Mark I., Reynolds, Richard, Robertson, Neil ORCID: https://orcid.org/0000-0002-5409-4909, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Howell, Owain W. 2016. Complement is activated in progressive multiple sclerosis cortical grey matter lesions. Journal of Neuroinflammation 13 , 161. 10.1186/s12974-016-0611-x

Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2016. The membrane attack complex as an inflammatory trigger. Immunobiology 221 (6) , pp. 747-751. 10.1016/j.imbio.2015.04.006

Williams, Pete A., Tribble, James R., Pepper, Keating W., Cross, Stephen D., Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Morgan, James E. ORCID: https://orcid.org/0000-0003-4075-7676, John, Simon W. M. and Howell, Gareth R. 2016. Inhibition of the classical pathway of the complement cascade prevents early dendritic and synaptic degeneration in glaucoma. Molecular Neurodegeneration 11 , 26. 10.1186/s13024-016-0091-6

Bloom, Anja C., Collins, Fraser L., van't Hof, Rob J., Ryan, Elizabeth S., Jones, Emma, Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Erlandsson, Malin, Bokarewa, Maria, Aeschlimann, Daniel ORCID: https://orcid.org/0000-0003-0930-7706, Evans, Bronwen A. J. ORCID: https://orcid.org/0000-0002-3082-1008 and Williams, Anwen S. ORCID: https://orcid.org/0000-0001-6118-020X 2016. Deletion of the membrane complement inhibitor CD59a drives age and gender-dependent alterations to bone phenotype in mice. Bone 84 , pp. 253-261. 10.1016/j.bone.2015.12.014

Bahia El Idrissi, N., Hakobyan, S., Ramaglia, V., Geluk, A., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Das, P. Kumar and Baas, F. 2016. Complement activation in leprosy: a retrospective study shows elevated circulating terminal complement complex in reactional leprosy. Clinical and Experimental Immunology 184 (3) , p. 338. 10.1111/cei.12767

Moore, G. R. Wayne, Laule, Cornelia, Leung, Esther, Pavlova, Vladimira, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Esiri, Margaret M. 2016. Complement and humoral adaptive immunity in the human choroid plexus: roles for stromal concretions, basement membranes, and epithelium. Journal of Neuropathology and Experimental Neurology 75 (5) , pp. 415-428. 10.1093/jnen/nlw017

Szarvas, Nóra, Szilágyi, Ágnes, Csuka, Dorottya, Takács, Beáta, Rusai, Krisztina, Müller, Thomas, Arbeiter, Klaus, Réti, Marienn, Haris, Ágnes, Wagner, László, Török, Szilárd, Kelen, Kata, Szabó, Attila J., Reusz, György S., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Prohászka, Zoltán 2016. Genetic analysis and functional characterization of novel mutations in a series of patients with atypical hemolytic uremic syndrome. Molecular Immunology 71 , pp. 10-22. 10.1016/j.molimm.2016.01.003

Serna, Marina, Giles, Joanna L., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Bubeck, Doryen 2016. Structural basis of complement membrane attack complex formation. Nature Communications 7 , 10587. 10.1038/ncomms10587

Triantafilou, Martha ORCID: https://orcid.org/0000-0002-8489-2602, Hughes, Timothy ORCID: https://orcid.org/0000-0003-2348-3490, Morgan, Bryan ORCID: https://orcid.org/0000-0003-4075-7676 and Triantafilou, Kathy ORCID: https://orcid.org/0000-0002-7473-6278 2016. Complementing the inflammasome. Immunology 147 (2) , pp. 152-164. 10.1111/imm.12556

Ruseva, Marieta M., Ramaglia, Valeria, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Harris, Claire L. 2015. An anticomplement agent that homes to the damaged brain and promotes recovery after traumatic brain injury in mice. Proceedings of the National Academy of Sciences 112 (46) , pp. 14319-14324. 10.1073/pnas.1513698112

Mook-Kanamori, B. B., Valls Serón, M., Geldhoff, M., Havik, S. R., van der Ende, A., Baas, F., van der Poll, T., Meijers, J. C. M., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Brouwer, M. C. and van de Beek, D. 2015. Thrombin-activatable fibrinolysis inhibitor influences disease severity in humans and mice with pneumococcal meningitis. Journal of Thrombosis and Haemostatis 13 (11) , pp. 2076-2086. 10.1111/jth.13132

Morgan, Bryan ORCID: https://orcid.org/0000-0003-4075-7676 2015. The role of complement in neurological and neuropsychiatric diseases. Expert Review of Clinical Immunology 11 (10) , pp. 1109-1119. 10.1586/1744666X.2015.1074039

Martínez-Barricarte, Rubén, Heurich-Sevcenco, Meike ORCID: https://orcid.org/0000-0003-0105-2702, López-Perrote, Andrés, Tortajada, Agustin, Pinto, Sheila, López-Trascasa, Margarita, Sánchez-Corral, Pilar, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Llorca, Oscar, Harris, Claire L. and Rodríguez de Córdoba, Santiago 2015. The molecular and structural bases for the association of complement C3 mutations with atypical hemolytic uremic syndrome. Molecular Immunology 66 (2) , pp. 263-273. 10.1016/j.molimm.2015.03.248

Kasanmoentalib, E. Soemirien, Valls Seron, Mercedes, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Brouwer, Matthijs C. and van de Beek, Diederik 2015. Adjuvant treatment with dexamethasone plus anti-C5 antibodies improves outcome of experimental pneumococcal meningitis: a randomized controlled trial. Journal of Neuroinflammation 12 (1) , 149. 10.1186/s12974-015-0372-y

Giles, Joanna L., Choy, Ernest ORCID: https://orcid.org/0000-0003-4459-8609, van den Berg, Carmen, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Harris, Claire L. 2015. Response to comment on 'Functional analysis of a complement polymorphism (rs17611) associated with rheumatoid arthritis'. Journal of Immunology 195 (1) , p. 4. 10.4049/jimmunol.1500968

Bahia El Idrissi, Nawal, Das, Pranab K., Fluiter, Kees, Rosa, Patricia S., Vreijling, Jeroen, Troost, Dirk, Morgan, Bryan ORCID: https://orcid.org/0000-0003-4075-7676, Baas, Frank and Ramaglia, Valeria 2015. M. leprae components induce nerve damage by complement activation: identification of lipoarabinomannan as the dominant complement activator. Acta Neuropathologica 129 (5) , pp. 653-667. 10.1007/s00401-015-1404-5

Ramaglia, V., Jackson, S. J., Hughes, Timothy ORCID: https://orcid.org/0000-0003-2348-3490, Neal, James, Baker, D. and Morgan, Bryan ORCID: https://orcid.org/0000-0003-4075-7676 2015. Complement activation and expression during chronic relapsing experimental autoimmune encephalomyelitis in the Biozzi ABH mouse. Clinical & Experimental Immunology 180 (3) , pp. 432-441. 10.1111/cei.12595

Owen, E. Patricia, Würzner, Reinhard, Leisegang, Felicity, Rizkallah, Pierre, Whitelaw, Andrew, Simpson, John, Thomas, Andrew David ORCID: https://orcid.org/0000-0002-5474-1205, Harris, Claire Louise, Giles, Joanna L., Hellerud, Bernt C., Mollnes, Tom E., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Potter, Paul C. and Orren, Ann 2015. A complement C5 gene mutation, c.754G>A:p.A252T, is common in the Western Cape, South Africa and found to be homozygous in seven percent of Black African meningococcal disease cases. Molecular Immunology 64 (1) , pp. 170-176. 10.1016/j.molimm.2014.11.010

Giles, Joanna, Choy, Ernest Ho Sing ORCID: https://orcid.org/0000-0003-4459-8609, Van Den Berg, Carmen, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Harris, Claire Louise 2015. Functional analysis of a complement polymorphism (rs17611) associated with rheumatoid arthritis. The Journal of Immunology 194 (7) , pp. 3029-3034. 10.4049/jimmunol.1402956

Subias, Marta, Tortajada, Agustin, Gastoldi, Sara, Galbusera, Miriam, Lopez-Perrote, Andres, Lopez, Lucia de Juana, Gonzalez-Fernandez, Fernando Ataulfo, Villegas-Martinez, Ana, Dominguez, Mercedes, Llorca, Oscar, Noris, Marina, Morgan, Bryan ORCID: https://orcid.org/0000-0003-4075-7676 and Rodriguez de Cordoba, Santiago 2014. A novel antibody against human factor B that blocks formation of the C3bB proconvertase and inhibits complement activation in disease models. The Journal of Immunology 193 (11) , pp. 5567-5575. 10.4049/jimmunol.1402013

Giles, J. L. ORCID: https://orcid.org/0000-0003-3143-6854, Choy, E. ORCID: https://orcid.org/0000-0003-4459-8609, van den Berg, C., Morgan, B. P. ORCID: https://orcid.org/0000-0003-4075-7676 and Harris, C. L. 2014. Functional analysis of a complement polymorphism (rs17611) associated with Rheumatoid Arthritis. Immunology 143 (s2) , pp. 181-182. 10.1111/imm.12407

Clark, Simon J., Schmidt, Christoph Q., White, Anne W., Hakobyan, Svetlana, Morgan, Bryan ORCID: https://orcid.org/0000-0003-4075-7676 and Bishop, Paul N. 2014. Identification of factor H-like protein 1 as the predominant complement regulator in Bruch's membrane: implications for age-related macular degeneration. The Journal of Immunology 193 (10) , pp. 4962-4970. 10.4049/jimmunol.1401613

Paixao-Cavalcante, Danielle, Torreira, Eva, Lindorfer, Margaret A., Rodriguez de Cordoba, Santiago, Morgan, Bryan ORCID: https://orcid.org/0000-0003-4075-7676, Taylor, Ronald P., Llorca, Oscar and Harris, Claire 2014. A humanized antibody that regulates the alternative pathway convertase: potential for therapy of renal disease associated with nephritic factors. The Journal of Immunology 192 (10) , pp. 4844-4851. 10.4049/jimmunol.1303131

Ingram, Gillian, Loveless, Sam ORCID: https://orcid.org/0000-0002-5124-4115, Howell, Owain W., Hakobyan, Svetlana, Dancey, Bethan, Harris, Claire L., Robertson, Neil P. ORCID: https://orcid.org/0000-0002-5409-4909, Neal, James W. and Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 2014. Complement activation in multiple sclerosis plaques: an immunohistochemical analysis. Acta Neuropathologica Communications 2 , 53. 10.1186/2051-5960-2-53

Fluiter, Kees, Opperhuizen, Anne Loes, Morgan, Bryan ORCID: https://orcid.org/0000-0003-4075-7676, Baas, Frank and Ramaglia, Valeria 2014. Inhibition of the membrane attack complex of the complement system reduces secondary neuroaxonal loss and promotes neurologic recovery after traumatic brain injury in mice. The Journal of Immunology 192 (5) , pp. 2339-2348. 10.4049/jimmunol.1302793

Pickering, Matthew C, D'Agati, Vivette D, Nester, Carla M, Smith, Richard J, Haas, Mark, Appel, Gerald B, Alpers, Charles E, Bajema, Ingeborg M, Bedrosian, Camille, Braun, Michael, Doyle, Mittie, Fakhouri, Fadi, Fervenza, Fernando C, Fogo, Agnes B, Frémeaux-Bacchi, Véronique, Gale, Daniel P, Goicoechea de Jorge, Elena, Griffin, Gene, Harris, Claire Louise, Holers, V Michael, Johnson, Sally, Lavin, Peter J, Medjeral-Thomas, Nicholas, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Nast, Cynthia C, Noel, Laure-Hélène, Peters, D Keith, Rodríguez de Córdoba, Santiago, Servais, Aude, Sethi, Sanjeev, Song, Wen-Chao, Tamburini, Paul, Thurman, Joshua M, Zavros, Michael and Cook, H Terence 2013. C3 glomerulopathy: consensus report. Kidney International 84 (6) , pp. 1079-1089. 10.1038/ki.2013.377

Liu, J, Copland, D, Horie, S, Wu, W, Chen, M, Xu, Y, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Mack, M, Xu, H, Nicholson, L and Dick, A 2013. Myeloid cells expressing VEGF and Arginase-1 following uptake of damaged retinal pigment epithelium suggests potential mechanism that drives the onset of choroidal angiogenesis in mice. PLoS ONE 8 (8) , e72935. 10.1371/journal.pone.0072935

Khandhadia, Samir, Hakobyan, Svetlana, Heng, Ling Z., Gibson, Jane, Adams, David H., Alexander, Graeme J., Gibson, Jonathan M., Martin, Keith R., Menon, Geeta, Nash, Kathryn, Sivaprasad, Sobha, Ennis, Sarah, Cree, Angela J., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Lotery, Andrew J. 2013. Age-related macular degeneration and modification of systemic complement factor H production through liver transplantation. Ophthalmology 120 (8) , pp. 1612-1618. 10.1016/j.ophtha.2013.01.004

Triantafilou, K. ORCID: https://orcid.org/0000-0002-7473-6278, Hughes, T. R. ORCID: https://orcid.org/0000-0003-2348-3490, Triantafilou, M. ORCID: https://orcid.org/0000-0002-7473-6278 and Morgan, B. P. ORCID: https://orcid.org/0000-0003-4075-7676 2013. The complement membrane attack complex triggers intracellular Ca2+ fluxes leading to NLRP3 inflammasome activation. Journal of Cell Science 126 (13) , pp. 2903-2913. 10.1242/jcs.124388

Laudisi, F., Spreafico, R., Evrard, M., Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490, Mandriani, B., Kandasamy, M., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Sivasankar, B. and Mortellaro, A. 2013. Cutting edge: The NLRP3 inflammasome links complement-mediated inflammation and IL-1β release. The Journal of Immunology 191 (3) , pp. 1006-1010. 10.4049/jimmunol.1300489

Killick, R., Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Lovestone, S. 2013. Corrigendum to “Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH” [Neurosci. Lett. 533 (2013) 96–99] [Corrigendum]. Neuroscience Letters 545 , p. 144. 10.1016/j.neulet.2013.05.004

Goicoechea de Jorge, E., Caesar, J. J. E., Malik, T. H., Patel, M., Colledge, M., Johnson, S., Hakobyan, Svetlana, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Harris, Claire Louise, Pickering, M. C. and Lea, S. M. 2013. Dimerization of complement factor H-related proteins modulates complement activation in vivo. Proceedings of the National Academy of Sciences of the United States of America 110 (12) , pp. 4685-4690. 10.1073/pnas.1219260110

Clark, S. J., Ridge, L. A., Herbert, A. P., Hakobyan, Svetlana, Mulloy, B., Lennon, R., Wurzner, R., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Uhrin, D., Bishop, P. N. and Day, A. J. 2013. Tissue-specific host recognition by complement factor H is mediated by differential activities of its glycosaminoglycan-binding regions. The Journal of Immunology 190 (5) , pp. 2049-2057. 10.4049/jimmunol.1201751

Killick, R., Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Lovestone, S. 2013. Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH. Neuroscience Letters 533 , pp. 96-99. 10.1016/j.neulet.2012.11.008

Kandasamy, Matheswaran, Ying, Poon C., Ho, Adrian W. S., Sumatoh, Hermi R., Schlitzer, Andreas, Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490, Kemeny, David M., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Ginhoux, Florent and Sivasankar, Baalasubramanian 2013. Complement mediated signaling on pulmonary CD103+ dendritic cells is critical for their migratory function in response to influenza infection. PLoS Pathogens 9 (1) , e1003115. 10.1371/journal.ppat.1003115

Adriani, Kirsten S., Brouwer, Matthijs C., Geldhoff, Madelijn, Baas, Frank, Zwinderman, Aeilko H., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Harris, Claire Louise, van der Ende, Arie and van de Beek, Diederik 2013. Common polymorphisms in the complement system and susceptiblity to bacterial meningitis. Journal of Infection 66 (3) , pp. 255-262. 10.1016/j.jinf.2012.10.008

Paixao Cavalcante, Danielle, López-Trascasa, Margarita, Skattum, Lillemor, Giclas, Patricia C, Goodship, Timothy H, de Córdoba, Santiago Rodríguez, Truedsson, Lennart, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Harris, Claire Louise 2012. Sensitive and specific assays for C3 nephritic factors clarify mechanisms underlying complement dysregulation. Kidney International 82 (10) , pp. 1084-1092. 10.1038/ki.2012.250

Harris, Claire Louise, Heurich, Meike ORCID: https://orcid.org/0000-0003-0105-2702, Rodriguez de Cordoba, Santiago and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2012. The complotype: dictating risk for inflammation and infection. Trends in Immunology 33 (10) , pp. 513-521. 10.1016/j.it.2012.06.001

Ingram, Gillian, Hakobyan, Svetlana, Hirst, Claire Louise, Harris, Claire Louise, Loveless, Samantha ORCID: https://orcid.org/0000-0002-5124-4115, Mitchell, John Paul, Pickersgill, Trevor, Robertson, Neil ORCID: https://orcid.org/0000-0002-5409-4909 and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2012. Systemic complement profiling in multiple sclerosis as a biomarker of disease state. Multiple Sclerosis Journal 18 (10) , pp. 1401-1411. 10.1177/1352458512438238

Kempshall, Emma, Thebault, Simon, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Harris, Claire Louise and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 2012. Complement-induced protection: an explanation for the limitations of cell-based tumour immunotherapies. Immunology and Cell Biology 90 (9) , pp. 869-871. 10.1038/icb.2012.30

Mizuno, Masashi, Ito, Yasuhiko and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2012. Exploiting the nephrotoxic effects of venom from the sea anemone, phyllodiscus semoni, to create a hemolytic uremic syndrome model in the rat. Marine Drugs 10 (7) , pp. 1582-1604. 10.3390/md10071582

Elvington, Michelle, Huang, Yuxiang, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Qiao, Fei, van Rooijen, Nico, Atkinson, Carl and Tomlinson, Stephen 2012. A targeted complement-dependent strategy to improve the outcome of mAb therapy, and characterization in a murine model of metastatic cancer. Blood 119 (25) , pp. 6043-6051. 10.1182/blood-2011-10-383232

Mizuno, Masashi, Ito, Yasuhiko, Mizuno, Tomohiro, Harris, Claire Louise, Suzuki, Yasuhiro, Okada, Noriko, Matsuo, Seiichi and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2012. Membrane complement regulators protect against fibrin exudation increases in a severe peritoneal inflammation model in rats. American Journal of Physiology-Renal Physiology 302 (10) , F1245-F1251. 10.1152/ajprenal.00652.2011

Sacks, Steven and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2012. Complement UK - how and why it started [Editorial]. Immunobiology 217 (2) , pp. 125-126. 10.1016/j.imbio.2011.05.001

Pappworth, Isabel Y., Hayes, Christine, Dimmick, Jason, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Holers, V. Michael and Marchbank, Kevin J. 2012. Mice expressing human CR1/CD35 have an enhanced humoral immune response to T-dependent antigens but fail to correct the effect of premature human CR2 expression. Immunobiology 217 (2) , pp. 147-157. 10.1016/j.imbio.2011.06.001

Ramaglia, Valeria, Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490, Donev, Rossen Mintchev, Ruseva, Marieta Milkova, Wu, Xiaobo, Huitinga, Inge, Baas, Frank, Neal, James William and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2012. C3-dependent mechanism of microglial priming relevant to multiple sclerosis. Proceedings of the National Academy of Sciences 109 (3) , pp. 965-970. 10.1073/pnas.1111924109

Gibson, J., Hakobyan, Svetlana, Cree, A. J., Collins, A., Harris, Claire Louise, Ennis, S., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Lotery, A. J. 2012. Variation in complement component C1 inhibitor in age-related macular degeneration. Immunobiology 217 (2) , pp. 251-255. 10.1016/j.imbio.2011.07.015

Thomas, Andrew David ORCID: https://orcid.org/0000-0002-5474-1205, Orren, Ann, Connaughton, J., Feighery, C., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Roberts, Andrew Glyn 2012. Characterization of a large genomic deletion in four Irish families with C7 deficiency. Molecular Immunology 50 (1-2) , pp. 57-59. 10.1016/j.molimm.2011.12.002

Ingram, Gillian, Hakobyan, Svetlana, Loveless, Samantha ORCID: https://orcid.org/0000-0002-5124-4115, Robertson, Neil ORCID: https://orcid.org/0000-0002-5409-4909 and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2011. Complement regulator factor H in multiple sclerosis. Journal of Cellular Biochemistry 112 (10) , pp. 2653-2654. 10.1002/jcb.23204

Paringe, Vishal, Bloom, A. C., Choy, Ernest Ho Sing ORCID: https://orcid.org/0000-0003-4459-8609, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X 2011. Compromised expression of the complement membrane inhibitor CD59a propagates age-related joint degeneration in mice [Poster Abstract]. Arthritis and Rheumatism 63 (s10) , S947-S947. 10.1002/art.33310

Bloom, Anja Constanze, Collins, Fraser, Evans, Bronwen Alice James ORCID: https://orcid.org/0000-0002-3082-1008, Aeschlimann, Daniel P. ORCID: https://orcid.org/0000-0003-0930-7706, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X 2011. CD59 an unexpected protective role in bone [Abstract]. Bone 48 , S161-S162.

de Córdoba, Santiago Rodríguez, Harris, Claire Louise, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Llorca, Oscar 2011. Lessons from functional and structural analyses of disease-associated genetic variants in the complement alternative pathway. Biochimica et Biophysica Acta - Molecular Basis of Disease 1812 (1) , pp. 12-22. 10.1016/j.bbadis.2010.09.002

Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2011. Therapeutic Agents for Hereditary Angioedema [Letter]. New England Journal of Medicine 364 (1) , p. 86.

Raby, Anne-Catherine ORCID: https://orcid.org/0000-0002-5354-5835, Holst, Benjamin, Davies, James Anthony ORCID: https://orcid.org/0000-0003-3569-4500, Colmont, Chantal Sophie, Laumonnier, Yves, Coles, Barbara, Shah, Sanjoy, Hall, Judith Elizabeth ORCID: https://orcid.org/0000-0002-6770-7372, Topley, Nicholas, Köhl, Jörg, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Labeta, Mario Oscar ORCID: https://orcid.org/0000-0001-5750-6983 2011. TLR activation enhances C5a-induced pro-inflammatory responses by negatively modulating the second C5a receptor, C5L2. European Journal of Immunology 41 (9) , pp. 2741-2752. 10.1002/eji.201041350

Lewis, Ruth D., Perry, Mark J., Guschina, Irina, Jackson, Christopher L., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490 2011. CD55 deficiency protects against atherosclerosis in ApoE-deficient mice via C3a modulation of lipid metabolism. American Journal of Pathology 179 (4) , pp. 1601-1607. 10.1016/j.ajpath.2011.06.015

Heurich, Meike ORCID: https://orcid.org/0000-0003-0105-2702, Martinez-Barricarte, Ruben, Francis, Nigel ORCID: https://orcid.org/0000-0002-4706-4795, Roberts, Dawn L., Rodriguez de Cordoba, Santiago, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Harris, Claire Louise 2011. Common polymorphisms in C3, factor B, and factor H collaborate to determine systemic complement activity and disease risk. Proceedings of the National Academy of Sciences of the United States of America 108 (21) , pp. 8761-8766. 10.1073/pnas.1019338108

Roversi, P., Johnson, S., Caesar, J. J. E., McLean, F., Leath, K. J., Tsiftsoglou, S. A., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Harris, Claire Louise, Sim, R. B. and Lea, S. M. 2011. Structural basis for complement factor I control and its disease-associated sequence polymorphisms. Proceedings of the National Academy of Sciences of the United States of America 108 (31) , pp. 12839-12844. 10.1073/pnas.1102167108

Bubeck, Doryen, Roversi, Pietro, Donev, Rossen Mintchev, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Llorca, Oscar and Lea, Susan M. 2011. Structure of human complement C8, a precursor to membrane attack. Journal of Molecular Biology 405 (2) , pp. 325-330. 10.1016/j.jmb.2010.10.031

Heurich, Bianca, el Idrissi, Nawal Bahia, Donev, Rossen Mintchev, Petri, Susanne, Claus, Peter, Neal, James, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Ramaglia, Valeria 2011. Complement upregulation and activation on motor neurons and neuromuscular junction in the SOD1 G93A mouse model of familial amyotrophic lateral sclerosis. Journal of Neuroimmunology 235 (1-2) , pp. 104-109. 10.1016/j.jneuroim.2011.03.011

Woehrl, Bianca, Brouwer, Matthijs C., Murr, Carmen, Heckenberg, Sebastiaan G.B., Baas, Frank, Pfister, Hans W., Zwinderman, Aeilko H., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Barnum, Scott R., Van der Ende, Arie, Koedel, Uwe and van de Beek, Diederik 2011. Complement component 5 contributes to poor disease outcome in humans and mice with pneumococcal meningitis. Journal of Clinical Investigation 121 (10) , pp. 3943-3953. 10.1172/JCI57522

Roversi, Pietro, Johnson, Steven, Caesar, Joseph J. E., McLean, Florence, Leath, Kirstin J., Tsiftsoglou, Stefanos A., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Harris, Claire Louise, Sim, Robert B. and Lea, Susan M. 2011. Structures of the rat complement regulator CrrY. Acta Crystallographica Section F: Structural Biology and Crystallization Communications 67 (7) , pp. 739-743. 10.1107/S1744309111016551

Lueck, K., Wasmuth, S., Williams, J., Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Lommatzsch, A., Greenwood, J., Moss, Sarah E. and Pauleikhoff, D. 2011. Sub-lytic C5b-9 induces functional changes in retinal pigment epithelial cells consistent with age-related macular degeneration. Eye 25 (8) , pp. 1074-1082. 10.1038/eye.2011.109

Martínez-Barricarte, Rubén, Heurich, Meike ORCID: https://orcid.org/0000-0003-0105-2702, Valdes-Cañedo, Francisco, Vazquez-Martul, Eduardo, Torreira, Eva, Montes, Tamara, Tortajada, Agustín, Pinto, Sheila, Lopez-Trascasa, Margarita, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Llorca, Oscar, Harris, Claire Louise and Rodríguez de Córdoba, Santiago 2010. Human C3 mutation reveals a mechanism of dense deposit disease pathogenesis and provides insights into complement activation and regulation. Journal of Clinical Investigation 120 (10) , pp. 3702-3712. 10.1172/JCI43343

Ingram, Gillian, Hakobyan, Svetlana, Hirst, Claire Louise, Harris, Claire Louise, Pickersgill, Trevor, Cossburn, Mark D., Loveless, Samantha ORCID: https://orcid.org/0000-0002-5124-4115, Robertson, Neil ORCID: https://orcid.org/0000-0002-5409-4909 and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2010. Complement regulator factor H as a serum biomarker of multiple sclerosis disease state. Brain 133 (6) , pp. 1602-1611. 10.1093/brain/awq085

Manickam, Balasubramanian, Jha, Purushottam, Hepburn, Natalie Jayne, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Harris, Claire Louise, Bora, Puran S. and Bora, Nalini S. 2010. Suppression of complement activation by recombinant Crry inhibits experimental autoimmune anterior uveitis (EAAU). Molecular Immunology 48 (1-3) , pp. 231-239. 10.1016/j.molimm.2010.08.006

Tediose, Teeo, Kolev, Martin Veselinov ORCID: https://orcid.org/0000-0002-7208-3875, Baalasubramanian, Sivasankar, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Donev, Rossen Mintchev 2010. Interplay between REST and nucleolin transcription factors: a key mechanism in the overexpression of genes upon increased phosphorylation [RETRACTED]. Nucleic Acids Research 38 (9) , pp. 2799-2812. 10.1093/nar/gkq013

Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2010. Hereditary Angioedema - Therapies Old and New [Editorial]. New England Journal of Medicine 363 (6) , pp. 581-583. 10.1056/NEJMe1006450

Clark, S. J., Perveen, R., Hakobyan, Svetlana, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Sim, R. B., Bishop, P. N. and Day, A. J. 2010. Impaired Binding of the Age-related Macular Degeneration-associated Complement Factor H 402H Allotype to Bruch's Membrane in Human Retina. Journal of Biological Chemistry 285 (39) , pp. 30192-30202. 10.1074/jbc.M110.103986

Bora, N. S., Jha, P., Lyzogubov, V. V., Kaliappan, S., Liu, J., Tytarenko, R. G., Fraser, Deborah A., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Bora, P. S. 2010. Recombinant Membrane-targeted Form of CD59 Inhibits the Growth of Choroidal Neovascular Complex in Mice. Journal of Biological Chemistry 285 (44) , pp. 33826-33833. 10.1074/jbc.M110.153130

Lewis, Ruth D., Jackson, Christopher L., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490 2010. The membrane attack complex of complement drives the progression of atherosclerosis in apolipoprotein E knockout mice. Molecular Immunology 47 (5) , pp. 1098-1105. 10.1016/j.molimm.2009.10.035

Johnson, S. A., Williams, J. M., Hakobyan, Svetlana, Richards, A., Perkins, Sarah, Marchbank, K. J., Goodship, T. H. J., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Taylor, Christopher Matthew ORCID: https://orcid.org/0000-0002-9146-9167 and Savage, C. O. S. 2010. Impact of compound heterozygous complement factor H mutations on development of atypical hemolytic uremic syndrome - A pedigree revisited. Molecular Immunology 47 (7-8) , pp. 1585-1591. 10.1016/j.molimm.2009.12.001

Ingram, Gillian, Hakobyan, Svetlana, Robertson, Neil ORCID: https://orcid.org/0000-0002-5409-4909 and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2010. Elevated plasma C4a levels in multiple sclerosis correlate with disease activity. Journal of Neuroimmunology 223 (1-2) , pp. 124-127. 10.1016/j.jneuroim.2010.03.014

Copland, D. A., Hussain, K., Baalasubramanian, Sivasankar, Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Xu, H., Dick, A. D. and Nicholson, L. B. 2010. Systemic and local anti-C5 therapy reduces the disease severity in experimental autoimmune uveoretinitis. Clinical and Experimental Immunology 159 (3) , pp. 303-314. 10.1111/j.1365-2249.2009.04070.x

Mizuno, Tomohiro, Mizuno, Masashi, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Noda, Yukihiro, Yamada, Kiyofumi, Okada, Noriko, Yuzawa, Yukio, Matsuo, Seiichi and Ito, Yasuhiko 2010. Specific collaboration between rat membrane complement regulators Crry and CD59 protects peritoneum from damage by autologous complement activation. Nephrology Dialysis Transplantation 26 (6) , pp. 1821-1830. 10.1093/ndt/gfq683

Harhausen, Denise, Khojasteh, Uldus, Stahel, Philip F, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Nietfeld, Wilfried, Dirnagl, Ulrich and Trendelenburg, George 2010. Membrane attack complex inhibitor CD59a protects against focal cerebral ischemia in mice. Journal of Neuroinflammation 7 , pp. 15-26. 10.1186/1742-2094-7-15

Qiao, Fei, Atkinson, Carl, Kindy, Mark S., Shunmugavel, Anandakumar, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Song, Hongbin and Tomlinson, Stephen 2010. The alternative and terminal pathways of complement mediate post-traumatic spinal cord inflammation and injury. American Journal of Pathology 177 (6) , pp. 3061-3070. 10.2353/ajpath.2010.100158

Ten, Vadim S., Yao, Jun, Ratner, Veniamin, Sosunov, Sergey, Fraser, Deborah A., Botto, Marina, Baalasubramanian, Sivasankar, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Silverstein, Samuel, Stark, Raymond, Polin, Richard, Vannucci, Susan J., Pinsky, David and Starkov, Anatoly A. 2010. Complement component C1q mediates mitochondria-driven oxidative stress in neonatal hypoxic-ischemic brain injury. Journal of Neuroscience 30 (6) , pp. 2077-2087. 10.1523/JNEUROSCI.5249-09.2010

Hakobyan, Svetlana, Tortajada, Agustín, Harris, Claire Louise, de Córdoba, Santiago R and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2010. Variant-specific quantification of factor H in plasma identifies null alleles associated with atypical hemolytic uremic syndrome. Kidney International 78 (8) , pp. 782-788. 10.1038/ki.2010.275

Ramaglia, Valeria, Tannemaat, Martijn Rudolf, de Kok, Maryla, Wolterman, Ruud, Vigar, Miriam Ann, King, Rosalind Helen Mary, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Baas, Frank 2009. Complement inhibition accelerates regeneration in a model of peripheral nerve injury. Molecular Immunology 47 (2-3) , pp. 302-309. 10.1016/j.molimm.2009.09.019

Tortajada, Agustin, Montes, Tamara, Martinez-Barricarte, Ruben, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Harris, Claire Louise and de Cordoba, Santiago Rodriguez 2009. The disease-protective complement factor H allotypic variant Ile62 shows increased binding affinity for C3b and enhanced cofactor activity. Human Molecular Genetics 18 (18) , pp. 3452-3461. 10.1093/hmg/ddp289

Ramaglia, Valeria, King, Rosalind Helen Mary, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Baas, Frank 2009. Deficiency of the complement regulator CD59a exacerbates Wallerian degeneration. Molecular Immunology 46 (8-9) , pp. 1892-1896. 10.1016/j.molimm.2009.01.017

Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490, Ross, Kirsty S., Cowan, Graeme J. M., Baalasubramanian, Sivasank, Harris, Claire Louise, Mitchell, Timothy J. and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2009. Identification of the high affinity binding site in the Streptococcus intermedius toxin intermedilysin for its membrane receptor, the human complement regulator CD59. Molecular Immunology 46 (7) , pp. 1561-1567. 10.1016/j.molimm.2009.01.003

Montes, Tamara, Tortajada, Agustin, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Rodriguez de Cordoba, Santiago and Harris, Claire Louise 2009. Functional basis of protection against age-related macular degeneration conferred by a common polymorphism in complement factor B. Proceedings of the National Academy of Sciences 106 (11) , pp. 4366-4371. 10.1073/pnas.0812584106

Scola, Anne-Marie, Johswich, Kay-Ole, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Klos, Andreas and Monk, Peter N. 2009. The human complement fragment receptor, C5L2, is a recycling decoy receptor. Molecular Immunology 46 (6) , pp. 1149-1162. 10.1016/j.molimm.2008.11.001

Ruseva, Marieta Milkova, Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490, Donev, Rossen Mintchev, Baalasubramanian, Sivasankar, Pickering, Matthew C., Wu, Xiaobo, Harris, Claire Louise and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2009. Crry deficiency in complement sufficient mice: C3 consumption occurs without associated renal injury. Molecular Immunology 46 (5) , pp. 803-811. 10.1016/j.molimm.2008.09.003

Kolev, Martin ORCID: https://orcid.org/0000-0002-7208-3875, Ruseva, Marieta Milkova, Harris, Claire Louise, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Donev, Rossen Mintchev 2009. Implication of complement system and its regulators in Alzheimer's Disease. Current Neuropharmacology 7 (1) , pp. 1-8.

Baalasubramanian, Sivasankar, Longhi, M. Paula, Gallagher, Kathleen M. E., Betts, Gareth J., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567 and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 2009. CD59 blockade enhances antigen-specific CD4+ T cell responses in humans: a new target for cancer immunotherapy? The Journal of Immunology 182 (9) , pp. 5203-5207. 10.4049/jimmunol.0804243

Arnold, D. F., Roberts, Andrew Glyn, Thomas, Anne Gwenllain, Ferry, B., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Chapel, H. 2009. A novel mutation in a patient with a deficiency of the eighth component of complement associated with recurrent meningococcal meningitis. Journal of Clinical Immunology 29 (5) , pp. 691-695. 10.1007/s10875-009-9295-7

Kolev, Martin ORCID: https://orcid.org/0000-0002-7208-3875, Tediose, Teeo, Baalasubramanian, Sivasankar, Harris, Claire Louise, Thome, J., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Donev, Rossen Mintchev 2009. Upregulating CD59: a new strategy for protection of neurons from complement-mediated degeneration. The Pharmacogenomics Journal 10 (1) , pp. 12-19. 10.1038/tpj.2009.52

Ingram, Gillian, Hakobyan, Svetlana, Robertson, Neil ORCID: https://orcid.org/0000-0002-5409-4909 and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2009. Complement in multiple sclerosis: its role in disease and potential as a biomarker. Clinical and Experimental Immunology 155 (2) , pp. 128-139. 10.1111/j.1365-2249.2008.03830.x

Stahel, Philip F, Flierl, Michael A, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Persigehl, Ivonne, Stoll, Christiane, Conrad, Claudia, Touban, Basel M, Smith, Wade R, Beauchamp, Kathryn, Schmidt, Oliver I, Ertel, Wolfgang and Leinhase, Iris 2009. Absence of the complement regulatory molecule CD59a leads to exacerbated neuropathology after traumatic brain injury in mice. Journal of Neuroinflammation 6 , pp. 2-13. 10.1186/1742-2094-6-2

Savage, D. B., Semple, R. K., Clatworthy, M. R., Lyons, P. A., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Cochran, E. K., Gorden, P., Raymond-Barker, P., Murgatroyd, P. R., Adams, C., Scobie, I., Mufti, G. J., Alexander, G. J. M., Thiru, S., Murano, I., Cinti, S., Chaudhry, A. N., Smith, K. G. C. and O'Rahilly, S. 2009. Complement Abnormalities in Acquired Lipodystrophy Revisited. Journal of Clinical Endocrinology & Metabolism 94 (1) , pp. 10-16. 10.1210/jc.2008-1703

McColl, Aisleen, Bournazos, Stylianos, Franz, Sandra, Perretti, Mauro, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Haslett, Christopher and Dransfield, Ian 2009. Glucocorticoids induce protein S-dependent phagocytosis of apoptotic neutrophils by human macrophages. The Journal of Immunology 183 (3) , pp. 2167-2175. 10.4049/jimmunol.0803503

Mizuno, Masashi, Ito, Yasuhiko, Hepburn, Natalie Jayne, Mizuno, Tomohiro, Noda, Yukihiro, Yuzawa, Yukio, Harris, Claire Louise, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Matsuo, Seiichi 2009. Zymosan, but not lipopolysaccharide, triggers severe and progressive peritoneal injury accompanied by complement activation in a rat peritonitis model. The Journal of Immunology 183 (2) , pp. 1403-1412. 10.4049/jimmunol.0804245

Hakobyan, Svetlana, Harris, Claire Louise, Van Den Berg, Carmen Wilma, Fernandez-Alonso, Maria Carmen, de Jorge, Elena Goicoechea, de Cordoba, Santiago Rodriguez, Rivas, German, Mangione, Palma, Pepys, Mark B. and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2008. Complement factor H binds to denatured rather than to native pentameric C-reactive protein. Journal of Biological Chemistry 283 (45) , pp. 30451-30460. 10.1074/jbc.M803648200

Donev, Rossen Mintchev, Gray, Lisa Clare, Baalasubramanian, Sivasankar, Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490, Van Den Berg, Carmen Wilma and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2008. Modulation of CD59 expression by restrictive silencer factor-derived peptides in cancer immunotherapy for neuroblastoma [RETRACTED]. Cancer Research 68 (14) , pp. 5979-5987. 10.1158/0008-5472.CAN-07-6828

Morton, Jonathan, Coles, Barbara, Wright, Kate Louise, Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004, Morrow, Jason D., Terry, Erin S., Anning, Peter, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Dioszeghy, Vincent, Kuhn, Hartmut, Chaitidis, Pavlos, Hobbs, Adrian J., Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 2008. Circulating neutrophils maintain physiological blood pressure by suppressing bacteria and IFN -dependent iNOS expression in the vasculature of healthy mice. Blood 111 (10) , pp. 5187-5194. 10.1182/blood-2007-10-117283

Ramaglia, Valeria, Wolterman, Ruud, de Kok, Maryla, Vigar, Miriam Ann, Wagenaar-Bos, Ineke, King, Rosalind Helen Mary, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Baas, Frank 2008. Soluble complement receptor 1 protects the peripheral nerve from early axon loss after injury. American Journal of Pathology 172 (4) , pp. 1043-1052. 10.2353/ajpath.2008.070660

Hepburn, Natalie Jayne, Ruseva, Marieta Milkova, Harris, Claire Louise and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2008. Complement, roles in renal disease and modulation for therapy. Clinical Nephrology 70 (5) , pp. 357-376.

Donev, Rossen Mintchev, Baalasubramanian, Sivasankar, Mizuno, Masashi and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2008. The mouse complement regulator CD59b is significantly expressed only in testis and plays roles in sperm acrosome activation and motility [RETRACTED]. Molecular Immunology 45 (2) , pp. 534-542. 10.1016/j.molimm.2007.05.011

Hepburn, Natalie Jayne, Chamberlain-Banoub, Jayne L., Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Harris, Claire Louise 2008. Prevention of experimental autoimmune myasthenia gravis by rat Crry-Ig: a model agent for long-term complement inhibition in vivo. Molecular Immunology 45 (2) , pp. 395-405. 10.1016/j.molimm.2007.06.144

Willison, Hugh J., Halstead, Susan K., Beveridge, Erin, Zitman, Femke M. P., Greenshields, Kay N., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Plomp, Jaap J. 2008. The role of complement and complement regulators in mediating motor nerve terminal injury in murine models of Guillain-Barré syndrome. Journal of Neuroimmunology 201 , pp. 172-182. 10.1016/j.jneuroim.2008.05.028

Leite, Maria Isabel, Jacob, Saiju, Viegas, Stuart, Cossins, Judy, Clover, Linda, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Beeson, David, Willcox, Nick and Vincent, Angela 2008. IgG1 antibodies to acetylcholine receptors in 'seronegative' myasthenia gravis. Brain 131 (7) , pp. 1940-1952. 10.1093/brain/awn092

Hakobyan, Svetlana, Harris, Claire Louise, Tortajada, Agustín, Goicochea de Jorge, Elena, Garcia-Layana, Alfredo, Fernandez-Robredo, Patricia, Rodriguez de Cordoba, Santiago and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2008. Measurement of factor H variants in plasma using variant-specific monoclonal antibodies: application to assessing risk of age-related macular degeneration. Investigative Ophthalmology and Visual Science 49 (5) , pp. 1983-1990. 10.1167/iovs.07-1523

Athisayaraj, T.W., Henley, P., Asderakis, A. ORCID: https://orcid.org/0000-0001-6859-2020, Morgan, B.P. ORCID: https://orcid.org/0000-0003-4075-7676 and Chavez, R. 2007. Complement activation associated to ischaemia and reperfusion in clinical renal transplantation. Molecular Immunology 44 (16) , p. 3935. 10.1016/j.molimm.2007.06.065

Hepburn, Natalie Jayne, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Harris, Claire Louise 2007. In Vivo Characterization and Therapeutic Efficacy of a C5-specific Inhibitor from the Soft Tick Ornithodoros moubata. J Biol Chem 282 , pp. 8292-8299. 10.1074/jbc.M609858200

Harris, Claire Louise, Cordoba, S. Rodriguez de, Jorge, E. Goicoechea de and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2007. Gain-of-function mutations in complement factor B are associated with atypical hemolytic uremic syndrome. Proceedings of the National Academy of Sciences 104 (1) , pp. 240-5. 10.1073/pnas.0603420103

Harris, Claire Louise, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Pettigrew, D.M. and Lea, S.M. 2007. Decay-accelerating factor must bind both components of the complement alternative pathway c3 convertase to mediate efficient decay. Journal of Immunology 178 , pp. 352-359.

Hepburn, Natalie J., Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Chamberlain, Jayne C., Hamer, Joseph, Nunn, M. A., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Harris, Claire Louise 2007. In vivo characterisation and therapeutic efficacy of a C5-specific inhibitor [Abstract]. Molecular Immunology 44 (1-3) , p. 183. 10.1016/j.molimm.2006.07.087

Mizuno, Masashi, Donev, Rossen Mark, Harris, Claire Louise and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2007. CD55 in rat male reproductive tissue: Differential expression in testis and expression of a unique truncated isoform on spermatozoa. Molecular Immunology 44 (7) , pp. 1613-1622. 10.1016/j.molimm.2006.08.018

Sivasankar, Baalasubramanian, Donev, Rossen Mintchev, Longhi, M. Paula, Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490, Davies, Ruth, Cole, Duncan Sean, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Marchbank, Kevin J. 2007. CD59a deficient mice display reduced B cell activity and antibody production in response to T-dependent antigens. Molecular Immunology 44 (11) , pp. 2978-2987. 10.1016/j.molimm.2006.12.025

Omidvar, Nader, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Longhi, M. Paula, Smith, Richard A. G. and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2006. Expression of glycosylphosphatidylinositol-anchored CD59 on target cells enhances human NK cell-mediated cytotoxicity. Journal of immunology 176 (5) , pp. 2915-2923.

Omidvar, Nader, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Longhi, Maria P., Smith, Richard A. G. and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2006. Expression of glycosylphosphatidylinositol-anchored CD59 on target cells enhances human NK cell-mediated cytotoxicity. The Journal of Immunology 176 (5) , pp. 2915-2923. 10.4049/jimmunol.176.5.2915

Donev, Rossen Mintchev, Cole, Duncan Sean, Sivanaskar, Baalasubramanian, Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490 and Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 2006. p53 regulates cellular resistance to complement lysis through enhanced expression of CD59 [RETRACTED]. Cancer Research 66 (4) , pp. 2451-8. 10.1158/0008-5472.CAN-05-3191

Donev, Rossen Mintchev and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2006. A quantitative method for comparison of expression of alternatively spliced genes using different primer pairs. Journal of Biochemical and Biophysical Methods 66 (1-3) , pp. 23-31. 10.1016/j.jbbm.2005.11.001

Longhi, M. Paula, Baalasubramanian, Sivasankar, Omidvar, Nader, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 2005. Cutting edge: murine CD59a modulates antiviral CD4+ T cell activity in a complement-independent manner. Journal of Immunology 175 (11) , pp. 7098-7102.

Harris, Claire Louise, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Lea, S. M. and Abbott, R. J. 2005. Molecular dissection of interactions between components of the alternative pathway of complement and decay accelerating factor (CD55). Journal of Biological Chemistry 280 (4) , pp. 2569-78. 10.1074/jbc.M410179200

Van Beek, J. and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2005. The role of complement in EAE. Lavi, E. and Constantinescu, C. S., eds. Experimental Models of Multple Sclerosis, Dordrecht: Kluwer Academic, pp. 245-267. (10.1007/0-387-25518-4_12)

Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Griffiths, M., Khanom, H., Taylor, S. M. and Neal, James William 2004. Blockade of the C5a receptor fails to protect against experimental autoimmune encephalomyelitis in rats. Clinical & Experimental Immunology 138 (3) , pp. 430-8. 10.1111/j.1365-2249.2004.02646.x

Baalasubramanian, Sivasankar, Harris, Claire Louise, Donev, Rossen Mintchev, Mizuno, Masashi, Omidvar, Nader, Song, Wen-Chao and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2004. CD59a is the primary regulator of membrane attack complex assembly in the mouse. Journal of Immunology 173 , pp. 3684-3692.

Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Mizuno, Masashi, Richards, Peter James, Holt, Dewi Stanley and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2004. Deletion of the gene encoding CD59a in mice increases disease severity in a murine model of rheumatoid arthritis. Arthritis & Rheumatism 50 (9) , pp. 3035-3044. 10.1002/art.20478

Rushmere, N. K., Knowlden, Janice Mary, Gee, Julia Margaret Wendy ORCID: https://orcid.org/0000-0001-6483-2015, Harper, Maureen Elaine, Robertson, J. F. R., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Nicholson, Robert Ian 2004. Analysis of the level of mRNA expression of the membrane regulators of complement, Cd59, Cd55 and Cd46, in breast, cancer. International Journal of Cancer 108 (6) , pp. 930-936. 10.1002/ijc.11606

Mead, Richard James, Neal, James William, Griffiths, Mark Raymond, Linington, Christopher, Botto, Marina, Lassmann, Hans and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2004. Deficiency of the complement regulator CD59a enhances disease severity, demyelination and axonal injury in murine acute experimental allergic encephalomyelitis. Laboratory Investigation 84 , pp. 21-28. 10.1038/labinvest.3700015

Harris, Claire Louise and Morgan, Bryan ORCID: https://orcid.org/0000-0003-4075-7676 2004. The many faces of the membrane regulators of complement. Szebeni, Janos, ed. The Complement System: Novel Roles in Health and Disease, Boston: Kluwer, pp. 129-166.

Sivasankar, B., Mizuno, Masashi, Donev, Rossen Mintchev, Omidvar, Nader, Harris, Claire Louise, Song, W. C. and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2004. CD59b is expressed at low level on mouse erythrocytes and has a negligible protective role in the presence of CD59a. Molecular Immunology 41 (2-3) , pp. 307-308. 10.1016/j.molimm.2004.03.002

Harris, Claire Louise, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Goodfellow, Ian, Evans, David J., Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2003. Generation of anti-complement 'prodrugs': cleavable reagents for specific delivery of complement regulators to disease sites. The Journal of Biological Chemistry 278 (38) , pp. 36068-36076. 10.1074/jbc.M306351200

Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Harris, Claire Louise, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Mason, Malcolm David ORCID: https://orcid.org/0000-0003-1505-2869 2003. Antigen-presenting cell exosomes are protected from complement-mediated lysis by expression of CD55 and CD59. European Journal of Immunology 33 (2) , pp. 522-31. 10.1002/immu.200310028

Spiller, Owen Bradley ORCID: https://orcid.org/0000-0002-9117-6911, Robinson, Mairi, O'Donnell, Elizabeth, Milligan, Steven, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Davison, Andrew J. and Blackbourn, David J. 2003. Complement regulation by Kaposi's sarcoma-associated herpesvirus ORF4 protein. Journal of Virology 77 (1) , pp. 592-599. 10.1128/JVI.77.1.592-599.2003

McGreal, Eamon Patrick, Ikawaki, N, Akatsu, H., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Gasque, Phillipe 2002. Human C1qRp is identical with CD93 and the mNI-11 antigen but does not bind C1q. Journal of Immunology 168 , pp. 5222-5232.

Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Van Den Berg, Carmen Wilma 2002. GPI-anchored GFP signals Ca2+ but is homogeneously distributed on the cell surface. Biochemical and Biophysical Research Communications 293 (2) , pp. 714-721. 10.1016/S0006-291X(02)00280-2

Okosieme, Onyebuchi E., Parkes, Arthur Burnham, McCullough, B., Doukidis, D., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Richards, C. J. and Lazarus, John Henry 2002. Complement activation in postpartum thyroiditis. QJM: An International Journal of Medicine 95 (3) , pp. 173-179. 10.1093/qjmed/95.3.173

Mead, Richard James, Singhrao, Simarjit Kaur, Neal, James William, Lassmann, H. and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2002. The membrane attack complex of complement causes severe demyelination associated with acute axonal injury. Journal of Immunology 168 , pp. 458-465.

Holt, Dewi Stanley, Botto, M., Bygrave, A. E., Hanna, S. M., Walport, M. J. and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2001. Targeted deletion of the CD59 gene causes spontaneous intravascular hemolysis and hemoglobinuria. Blood 98 (2) , pp. 442-9. 10.1182/blood.V98.2.442

Gasque, Philippe, Dean, Y. D., McGreal, Eamon Patrick, VanBeek, J. and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2000. Complement components of the innate immune system in health and disease in the CNS. Immunopharmacology 49 (1-2) , pp. 171-186. 10.1016/S0162-3109(00)80302-1

Labeta, Mario ORCID: https://orcid.org/0000-0001-5750-6983, Vidal, K., Rey Nores, J. E., Arias, M., Vita, N., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Guillemot, J.C., Loyaux, D., Ferrara, P., Schmid, D., Affolter, M., Borysiewicz, L. K., Donnet-Hughes, A. and Schiffrin, E. J. 2000. Innate recognition of bacteria in human milk is mediated by a milk-derived highly expressed pattern recognition receptor, soluble CD14. Journal of Experimental Medicine 191 , pp. 1807-1812. 10.1084/jem.191.10.1807

Orren, Ann 2000. Screening for complement deficiency. Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, ed. Complement Methods and Protocols, Vol. 150. Methods in Molecular Biology, Springer, pp. 139-158. (10.1385/1-59259-056-X:139)

Jones, J., Davies, E., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X 1996. Effect of inhibitors of tyrosine kinase and phospholipase C on neutrophil response to perforin attack. Immunology 89 (Supp1) , R187-R187.

Van Den Berg, Carmen Wilma, Cinek, Tomas, Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X, Horejsi, Vaclav and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 1995. Exogenous CD59 incorporated into U937 cells through its glycosyl phosphatidylinositol anchor becomes associated with signalling molecules in a time dependent manner. Biochemical Society Transactions 23 (2) , 269S. 10.1042/bst023269s

Taylor, Kathryn Mary ORCID: https://orcid.org/0000-0002-9576-9490, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Campbell, Anthony Keith 1994. Altered glycosylation and selected mutation in recombinant human complement component C9: effects on haemolytic activity. Immunology 83 (3) , pp. 501-506.