Browse by Current Cardiff authors

Smart, Sophie E. ORCID: https://orcid.org/0000-0002-6709-5425, Legge, Sophie E., Fenner, Eilidh, Pardiñas, Antonio F. ORCID: https://orcid.org/0000-0001-6845-7590, Woolway, Grace, Lynham, Amy J. ORCID: https://orcid.org/0000-0002-3189-6888, Escott‐Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009, Wilkinson, Lawrence ORCID: https://orcid.org/0000-0002-9337-6124, Holmans, Peter ORCID: https://orcid.org/0000-0003-0870-9412, O'Donovan, Michael C. ORCID: https://orcid.org/0000-0001-7073-2379, Owen, Michael J. ORCID: https://orcid.org/0000-0003-4798-0862 and Walters, James T.R. ORCID: https://orcid.org/0000-0002-6980-4053 2025. The role of SLC39A8.p.( Ala391Thr ) in schizophrenia symptom severity and cognitive ability: cross‐sectional studies of schizophrenia and the general UK population. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 198 (7) , pp. 135-146. 10.1002/ajmg.b.33037

Moon, Anna ORCID: https://orcid.org/0000-0002-6587-4425, Mawson, Eleanor, Gasalla, Patricia, Wilkinson, Lawrence ORCID: https://orcid.org/0000-0002-9337-6124, Dwyer, Dominic ORCID: https://orcid.org/0000-0001-8069-5508, Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009 and Thomas, Kerrie ORCID: https://orcid.org/0000-0003-3355-9583 2025. Reduced gene dosage of the psychiatric risk gene Cacna1c is associated with impairments in hypothalamic–pituitary–adrenal axis activity in rats. International Journal of Molecular Sciences 26 (12) , 5547. 10.3390/ijms26125547

Gasalla, Patricia, Thomas, Kerrie L. ORCID: https://orcid.org/0000-0003-3355-9583, Wilkinson, Lawrence ORCID: https://orcid.org/0000-0002-9337-6124, Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009 and Dwyer, Dominic Michael ORCID: https://orcid.org/0000-0001-8069-5508 2025. Reduced cacna1c expression produces anhedonic reactions to palatable sucrose in rats: No interactions with juvenile or adult stress. Genes, Brain and Behavior 24 (2) , e70021. 10.1111/gbb.70021

Haddon, Josephine E. ORCID: https://orcid.org/0000-0001-5975-813X, Titherage, Daniel, Heckenast, Julia R., Carter, Jennifer, Owen, Michael J. ORCID: https://orcid.org/0000-0003-4798-0862, Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009, Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124 and Jones, Matthew W. 2024. Linking haploinsufficiency of the autism- and schizophrenia-associated gene Cyfip1 with striatal-limbic-cortical network dysfunction and cognitive inflexibility. Translational Psychiatry 14 (1) , 256. 10.1038/s41398-024-02969-x

Correa-da-Silva, Felipe, Carter, Jenny, Wang, Xin-Yuan, Sun, Rui, Pathak, Ekta, Kuhn, José Manuel Monroy, Schriever, Sonja C., Maya-Monteiro, Clarissa M., Jiao, Han, Kalsbeek, Martin J., Moraes-Vieira, Pedro M. M., Gille, Johan J. P., Sinnema, Margje, Stumpel, Constance T. R. M., Curfs, Leopold M. G., Stenvers, Dirk Jan, Pfluger, Paul T., Lutter, Dominik, Pereira, Alberto M., Kalsbeek, Andries, Fliers, Eric, Swaab, Dick F., Wilkinson, Lawrence ORCID: https://orcid.org/0000-0002-9337-6124, Gao, Yuanqing and Yi, Chun-Xia 2024. Microglial phagolysosome dysfunction and altered neural communication amplify phenotypic severity in Prader-Willi Syndrome with larger deletion. Acta Neuropathologica 147 , 64. 10.1007/s00401-024-02714-0

Bosworth, Matthew L. ORCID: https://orcid.org/0000-0003-1391-7515, Isles, Anthony R. ORCID: https://orcid.org/0000-0002-7587-5712, Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124 and Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799 2024. Sex-dependent effects of Setd1a haploinsufficiency on development and adult behaviour. PLoS ONE 10.1371/journal.pone.0298717

Griesius, Simonas, Waldron, Sophie, Kamenish, Katie A., Cherbanich, Nick, Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124, Thomas, Kerrie L. ORCID: https://orcid.org/0000-0003-3355-9583, Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009, Mellor, Jack R., Dwyer, Dominic M. ORCID: https://orcid.org/0000-0001-8069-5508 and Robinson, Emma S. J. 2023. A mild impairment in reversal learning in a bowl-digging substrate deterministic task but not other cognitive tests in the Dlg2+/- rat model of genetic risk for psychiatric disorder. Genes, Brain and Behavior 22 (6) , e12865. 10.1111/gbb.12865

Clifton, Nicholas ORCID: https://orcid.org/0000-0003-2597-5253, Bosworth, Matthew ORCID: https://orcid.org/0000-0003-1391-7515, Haan, Niels, Rees, Elliott ORCID: https://orcid.org/0000-0002-6168-9222, Holmans, Peter ORCID: https://orcid.org/0000-0003-0870-9412, Wilkinson, Lawrence ORCID: https://orcid.org/0000-0002-9337-6124, Isles, Anthony ORCID: https://orcid.org/0000-0002-7587-5712, Collins, Mark and Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009 2022. Developmental disruption to the cortical transcriptome and synaptosome in a model of SETD1A loss-of-function. Human Molecular Genetics 31 (18) , pp. 3095-3106. 10.1093/hmg/ddac105

Silva, Ana I. ORCID: https://orcid.org/0000-0002-1184-4909, Ehrhart, Friederike, Ulfarsson, Magnus O., Stefansson, Hreinn, Stefansson, Kari, Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124, Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009 and Linden, David E.J. ORCID: https://orcid.org/0000-0002-5638-9292 2022. Neuroimaging findings in neurodevelopmental copy number variants: identifying molecular pathways to convergent phenotypes. Biological Psychiatry 92 (5) , pp. 341-361. 10.1016/j.biopsych.2022.03.018

Griesius, Simonas, O'Donnell, Cian, Waldron, Sophie, Thomas, Kerrie L. ORCID: https://orcid.org/0000-0003-3355-9583, Dwyer, Dominic M. ORCID: https://orcid.org/0000-0001-8069-5508, Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124, Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009, Robinson, Emma S. J. and Mellor, Jack R. 2022. Reduced expression of the psychiatric risk gene DLG2 (PSD93) impairs hippocampal synaptic integration and plasticity. Neuropsychopharmacology 47 , pp. 1367-1378. 10.1038/s41386-022-01277-6

Westacott, Laura and Wilkinson, Lawrence ORCID: https://orcid.org/0000-0002-9337-6124 2022. Complement dependent synaptic reorganisation during critical periods of brain development and risk for psychiatric disorder. Frontiers in Neuroscience 16 , 840266. 10.3389/fnins.2022.840266

Waldron, Sophie, Pass, Rachel ORCID: https://orcid.org/0000-0002-3652-0126, Griesius, Simonas, Mellor, Jack R., Robinson, Emma S. J., Thomas, Kerrie L. ORCID: https://orcid.org/0000-0003-3355-9583, Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009 and Dwyer, Dominic M. ORCID: https://orcid.org/0000-0001-8069-5508 2022. Behavioural and molecular characterisation of the Dlg2 haploinsufficiency rat model of genetic risk for psychiatric disorder. Genes, Brain and Behavior 21 (4) , e12797. 10.1111/gbb.12797

Pass, Rachel ORCID: https://orcid.org/0000-0002-3652-0126, Haan, Niels, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124, Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009 and Thomas, Kerrie L. ORCID: https://orcid.org/0000-0003-3355-9583 2022. Selective behavioural impairments in mice heterozygous for the cross disorder psychiatric risk gene DLG2. Genes, Brain and Behavior 21 (4) , e12799. 10.1111/gbb.12799

Westacott, Laura J., Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Haan, Niels, Brain, Sophie A., Bush, Emma-Louise, Toneva, Margarita, Baloc, Andreea-Ingrid, Moon, Anna L. ORCID: https://orcid.org/0000-0002-6587-4425, Reddaway, Jack, Owen, Michael J. ORCID: https://orcid.org/0000-0003-4798-0862, Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009, Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Gray, William P. ORCID: https://orcid.org/0000-0001-7595-8887 and Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124 2022. Complement C3 and C3aR mediate different aspects of emotional behaviours; relevance to risk for psychiatric disorder. Brain, Behavior, and Immunity 99 , pp. 70-82. 10.1016/j.bbi.2021.09.005

Westacott, Laura J., Haan, Niels, Evison, Claudia, Marei, Omar, Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009, Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490, Zaben, Malik ORCID: https://orcid.org/0000-0002-7446-4532, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124 and Gray, William P. ORCID: https://orcid.org/0000-0001-7595-8887 2021. Dissociable effects of complement C3 and C3aR on survival and morphology of adult born hippocampal neurons, pattern separation, and cognitive flexibility in male mice. Brain, Behavior, and Immunity 98 , pp. 136-150. 10.1016/j.bbi.2021.08.215

Silva, Ana I. ORCID: https://orcid.org/0000-0002-1184-4909, Kirov, George ORCID: https://orcid.org/0000-0002-3427-3950, Kendall, Kimberley M. ORCID: https://orcid.org/0000-0002-6755-6121, Bracher-Smith, Mathew, Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124, Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009, Ulfarsson, Magnus O., Walters, G. Bragi, Stefansson, Hreinn, Stefansson, Kari, Linden, David E.J. ORCID: https://orcid.org/0000-0002-5638-9292 and Caseras, Xavier ORCID: https://orcid.org/0000-0002-8490-6891 2021. Analysis of diffusion tensor imaging data from the UK Biobank confirms dosage effect of 15q11.2 copy number variation on white matter and shows association with cognition. Biological Psychiatry 90 (5) , pp. 307-316. 10.1016/j.biopsych.2021.02.969

Tigaret, Cezar M. ORCID: https://orcid.org/0000-0001-5848-6697, Tzu-Ching, E. Lin, Morrell, Edward R., Sykes, Lucy, Moon, Anna L. ORCID: https://orcid.org/0000-0002-6587-4425, O'Donovan, Michael ORCID: https://orcid.org/0000-0001-7073-2379, Owen, Michael J. ORCID: https://orcid.org/0000-0003-4798-0862, Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124, Jones, Matthew W., Thomas, Kerrie L. ORCID: https://orcid.org/0000-0003-3355-9583 and Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009 2021. Neurotrophin receptor activation rescues cognitive and synaptic abnormalities caused by hemizygosity of the psychiatric risk gene Cacna1c. Molecular Psychiatry 26 , pp. 1748-1760. 10.1038/s41380-020-01001-0

Haan, Niels, Westacott, Laura J., Carter, Jenny, Owen, Michael J. ORCID: https://orcid.org/0000-0003-4798-0862, Gray, William P. ORCID: https://orcid.org/0000-0001-7595-8887, Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009 and Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124 2021. Haploinsufficiency of the schizophrenia and autism risk gene Cyfip1 causes abnormal postnatal hippocampal neurogenesis through microglial and Arp2/3 mediated actin dependent mechanisms. Translational Psychiatry 11 (1) , 313. 10.1038/s41398-021-01415-6

Moon, Anna L ORCID: https://orcid.org/0000-0002-6587-4425, Brydges, Nichola M, Wilkinson, Lawrence S ORCID: https://orcid.org/0000-0002-9337-6124, Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009 and Thomas, Kerrie L ORCID: https://orcid.org/0000-0003-3355-9583 2020. Cacna1c hemizygosity results in aberrant fear conditioning to neutral stimuli. Schizophrenia Bulletin 46 (5) , pp. 1231-1238. 10.1093/schbul/sbz127

Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Smith, Georgia E., Small, Rebecca, Davies, William ORCID: https://orcid.org/0000-0002-7714-2440, Carter, Jenny, Bentley, Chloe A., Winstanley, Catharine A., Rogers, Robert D. and Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124 2020. Effects of 5-HT2C, 5-HT1A receptor challenges and modafinil on the initiation and persistence of gambling behaviours. Psychopharmacology 237 , pp. 1745-1756. 10.1007/s00213-020-05496-x

Clifton, Nicholas E. ORCID: https://orcid.org/0000-0003-2597-5253, Thomas, Kerrie L. ORCID: https://orcid.org/0000-0003-3355-9583, Wilkinson, Lawrence S ORCID: https://orcid.org/0000-0002-9337-6124, Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009 and Trent, Simon ORCID: https://orcid.org/0000-0001-9563-4281 2020. FMRP and CYFIP1 at the synapse and their role in psychiatric vulnerability. Complex Psychiatry 10.1159/000506858

Chapman, Ria M, Tinsley, Caroline L, Hill, Matthew J ORCID: https://orcid.org/0000-0001-6776-8709, Forrest, Marc P, Tansey, Katherine E, Pardinas, Antonio F. ORCID: https://orcid.org/0000-0001-6845-7590, Rees, Elliott ORCID: https://orcid.org/0000-0002-6168-9222, Doyle, A. Michelle, Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124, Owen, Michael J. ORCID: https://orcid.org/0000-0003-4798-0862, O'Donovan, Michael ORCID: https://orcid.org/0000-0001-7073-2379 and Blake, Derek J. ORCID: https://orcid.org/0000-0002-5005-4731 2019. Convergent evidence that ZNF804A is a regulator of pre-messenger RNA processing and gene expression. Schizophrenia Bulletin 45 (6) , pp. 1267-1278. 10.1093/schbul/sby183

Sykes, Lucy, Haddon, Josephine ORCID: https://orcid.org/0000-0001-5975-813X, Lancaster, Thomas M. ORCID: https://orcid.org/0000-0003-1322-2449, Sykes, Arabella, Azzouni, Karima, Niklas, Ihssen, Moon, Anna L. ORCID: https://orcid.org/0000-0002-6587-4425, Lin, Tzu-Ching E., Linden, David E. ORCID: https://orcid.org/0000-0002-5638-9292, Owen, Michael J. ORCID: https://orcid.org/0000-0003-4798-0862, O'Donovan, Michael C. ORCID: https://orcid.org/0000-0001-7073-2379, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124, Thomas, Kerrie L. ORCID: https://orcid.org/0000-0003-3355-9583 and Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009 2019. Genetic variation in the psychiatric risk gene CACNA1C modulates reversal learning across species. Schizophrenia Bulletin 45 (5) , pp. 1024-1032. 10.1093/schbul/sby146

Davies, Jennifer R. ORCID: https://orcid.org/0000-0001-7415-6129, Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124, Isles, Anthony R. ORCID: https://orcid.org/0000-0002-7587-5712 and Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799 2019. Prader-Willi syndrome imprinting centre deletion mice have impaired baseline and 5-HT2CR-mediated response inhibition. Human Molecular Genetics 28 (18) , pp. 3013-3023. 10.1093/hmg/ddz100

Silva, Ana I., Haddon, Josephine E., Syed, Yasir Ahmed ORCID: https://orcid.org/0000-0001-9495-307X, Trent, Simon ORCID: https://orcid.org/0000-0001-9563-4281, Tzu-Ching, E. Lin, Patel, Yateen, Carter, Jenny, Haan, Niels, Honey, Robert C. ORCID: https://orcid.org/0000-0001-6870-1880, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Assaf, Yaniv, Owen, Michael J. ORCID: https://orcid.org/0000-0003-4798-0862, Linden, David E. J. ORCID: https://orcid.org/0000-0002-5638-9292, Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009 and Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124 2019. Cyfip1 haploinsufficient rats show white matter changes, myelin thinning, abnormal oligodendrocytes and behavioural inflexibility. Nature Communications 10 , 3455. 10.1038/s41467-019-11119-7

Silva, Ana I. ORCID: https://orcid.org/0000-0002-1184-4909, Ulfarsson, Magnus O., Stefansson, Hreinn, Gustafsson, Omar, Walters, G. Bragi, Linden, David E.J. ORCID: https://orcid.org/0000-0002-5638-9292, Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124, Drakesmith, Mark ORCID: https://orcid.org/0000-0001-8574-9560, Owen, Michael J. ORCID: https://orcid.org/0000-0003-4798-0862, Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009 and Stefansson, Kari 2019. Reciprocal white matter changes associated with copy number variation at 15q11.2 BP1-BP2: A diffusion tensor imaging study. Biological Psychiatry 85 (7) , pp. 563-572. 10.1016/j.biopsych.2018.11.004

Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Patel, Yateen, Carter, Jenny, Stokes, Laura-Jean G., Rogers, Robert D. and Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124 2019. Feeding behaviour, risk-sensitivity and response control: effects of 5-HT 2C receptor manipulations. Philosophical Transactions B: Biological Sciences 374 (1766) , 20180144. 10.1098/rstb.2018.0144

Davies, William ORCID: https://orcid.org/0000-0002-7714-2440 and Wilkinson, Lawrence ORCID: https://orcid.org/0000-0002-9337-6124 2019. Editorial overview: special issue on epigenetics and genomic imprinting. Current Opinion in Behavioral Sciences 25 , iii-v. 10.1016/j.cobeha.2018.12.006

Iliescu, Adela F. ORCID: https://orcid.org/0000-0001-6642-9385, Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009, Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124, Dwyer, Dominic M. ORCID: https://orcid.org/0000-0001-8069-5508 and Honey, R. C. ORCID: https://orcid.org/0000-0001-6870-1880 2018. The nature of phenotypic variation in Pavlovian conditioning. Journal of Experimental Psychology: Animal Learning and Cognition 44 (4) , pp. 358-369. 10.1037/xan0000177

Moon, Anna L. ORCID: https://orcid.org/0000-0002-6587-4425, Haan, Niels, Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124, Thomas, Kerrie L. ORCID: https://orcid.org/0000-0003-3355-9583 and Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009 2018. CACNA1C: Association with pychiatric disorders, behavior, and neurogenesis. Schizophrenia Bulletin 44 (5) , pp. 958-965. 10.1093/schbul/sby096

Dent, Claire L., Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Lewis, Katie, Ward, Andrew, Fischer-Colbrie, Reiner, Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124, Wilkins, Jon F. and Isles, Anthony R. ORCID: https://orcid.org/0000-0002-7587-5712 2018. Impulsive choice in mice lacking paternal expression of Grb10 suggests intragenomic conflict in behavior. Genetics 209 (1) , pp. 233-239. 10.1534/genetics.118.300898

Liu, Yia-Ping, Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124 and Robbins, Trevor W. 2017. ‘Waiting impulsivity’ in isolation-reared and socially-reared rats: effects of amphetamine. Psychopharmacology 234 (9-10) , pp. 1587-1601. 10.1007/s00213-017-4579-8

Clifton, N. E. ORCID: https://orcid.org/0000-0003-2597-5253, Pocklington, A. J. ORCID: https://orcid.org/0000-0002-2137-0452, Scholz, B., Rees, E. ORCID: https://orcid.org/0000-0002-6168-9222, Walters, J. T. R. ORCID: https://orcid.org/0000-0002-6980-4053, Kirov, G. ORCID: https://orcid.org/0000-0002-3427-3950, O'Donovan, M. C. ORCID: https://orcid.org/0000-0001-7073-2379, Owen, M. J. ORCID: https://orcid.org/0000-0003-4798-0862, Wilkinson, L. S. ORCID: https://orcid.org/0000-0002-9337-6124, Thomas, K. L. ORCID: https://orcid.org/0000-0003-3355-9583 and Hall, J. ORCID: https://orcid.org/0000-0003-2737-9009 2017. Schizophrenia copy number variants and associative learning. Molecular Psychiatry 22 (2) , pp. 178-182. 10.1038/mp.2016.227

Garfield, Alastair S., Davies, Jennifer S., Burke, Luke K., Furby, Hannah ORCID: https://orcid.org/0000-0002-7279-1812, Wilkinson, Lawrence ORCID: https://orcid.org/0000-0002-9337-6124, Heisler, Lora K. and Isles, Anthony Roger ORCID: https://orcid.org/0000-0002-7587-5712 2016. Increased alternate splicing of Htr2c in a mouse model for Prader-Willi syndrome leads disruption of 5HT2C receptor mediated appetite. Molecular Brain 9 , 95. 10.1186/s13041-016-0277-4

Dent, Claire, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Swaden Lewis, Katie J., Plagge, A, Fischer-Colbrie, R, Wilkins, J. F., Wilkinson, Lawrence ORCID: https://orcid.org/0000-0002-9337-6124 and Isles, Anthony Roger ORCID: https://orcid.org/0000-0002-7587-5712 2016. Impulsive choices in mice lacking imprinted Nesp55. Genes, Brain and Behavior 15 (8) , pp. 693-701. 10.1111/gbb.12316

Scholz, Birger, Doidge, Amie N., Barnes, Philip, Hall, Jeremy ORCID: https://orcid.org/0000-0003-2737-9009, Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124 and Thomas, Kerrie L. ORCID: https://orcid.org/0000-0003-3355-9583 2016. The regulation of cytokine networks in hippocampal CA1 differentiates extinction from those required for the maintenance of contextual fear memory after recall. PLoS ONE 11 (5) , e0153102. 10.1371/journal.pone.0153102

Heckenast, Julia R., Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 and Jones, Matthew W. 2015. Decoding advances in psychiatric genetics: a focus on neural circuits in rodent models. Advances in Genetics 92 , pp. 75-106. 10.1016/bs.adgen.2015.09.001

Hinton, Robert, Opoka, Amy, Ojarikre, Obah A., Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 and Davies, William ORCID: https://orcid.org/0000-0002-7714-2440 2015. Preliminary evidence for aortopathy and an x-linked parent-of-origin effect on aortic valve malformation in a mouse model of Turner syndrome. Journal of Cardiovascular Development and Disease 2 (3) , pp. 190-199. 10.3390/jcdd2030190

Davies, Jennifer R. ORCID: https://orcid.org/0000-0001-7415-6129, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Dwyer, Dominic M. ORCID: https://orcid.org/0000-0001-8069-5508, Garfield, Alastair S., Furby, Hannah ORCID: https://orcid.org/0000-0002-7279-1812, Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124, Wells, Timothy ORCID: https://orcid.org/0000-0003-3618-0595 and Isles, Anthony Roger ORCID: https://orcid.org/0000-0002-7587-5712 2015. Calorie seeking, but not hedonic response, contributes to hyperphagia in a mouse model for Prader-Willi syndrome. European Journal of Neuroscience 42 (4) , pp. 2105-2113. 10.1111/ejn.12972

Davies, William ORCID: https://orcid.org/0000-0002-7714-2440, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Trent, Simon ORCID: https://orcid.org/0000-0001-9563-4281, Eddy, Jessica B., Ojarikre, Obah A. and Wilkinson, Lawrence S. ORCID: https://orcid.org/0000-0002-9337-6124 2014. Genetic and pharmacological modulation of the steroid sulfatase axis improves response control; comparison to drugs used in ADHD. Neuropsychopharmacology 39 , pp. 2622-2632. 10.1038/npp.2014.115

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Isles, Anthony Roger ORCID: https://orcid.org/0000-0002-7587-5712 and Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 2000. Imprinted genes, cognition and behaviour. Trends in Cognitive Sciences 4 (8) , pp. 309-318. 10.1016/S1364-6613(00)01504-7

Collins, P., Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124, Everitt, B. J., Robbins, T. W. and Roberts, A. C. 2000. The effect of dopamine depletion from the caudate nucleus of the common marmoset (Callithrix jacchus) on tests of prefrontal cognitive function. Behavioral Neuroscience 114 (1) , pp. 3-17. 10.1037/0735-7044.114.1.3

Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Laird, Fiona M., Davies, William ORCID: https://orcid.org/0000-0002-7714-2440 and Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 1999. Visuospatial attentional functioning in mice: interactions between cholinergic manipulations and genotype. European Journal of Neuroscience 11 (8) , pp. 2813-2823. 10.1046/j.1460-9568.1999.00701.x

Hall, F. S., Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799 and Robbins, T. W. 1999. Maternal deprivation of neonatal rats produces enduring changes in dopamine function. Synapse 32 (1) , pp. 37-43. 10.1002/(SICI)1098-2396(199904)32:1<37::AID-SYN5>3.0.CO;2-4

Ward, B.O, Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124, Robbins, T.W and Everitt, B.J 1999. Forebrain serotonin depletion facilitates the acquisition and performance of a conditional visual discrimination task in rats. Behavioural Brain Research 100 (1-2) , pp. 51-65. 10.1016/S0166-4328(98)00112-0

Hall, F. S., Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Inglis, W., Kendall, D. A., Marsden, C. A. and Robbins, T. W. 1998. Isolation rearing in rats: Pre- and postsynaptic changes in striatal dopaminergic systems. Pharmacology, Biochemistry and Behavior 59 (4) , pp. 859-872. 10.1016/S0091-3057(97)00510-8

Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Killcross, Andrew Simon, Torres, EM, Everitt, B. J. and Robbins, T. W. 1998. Dissociations in dopamine release in medial prefrontal cortex and ventral striatum during the acquisition and extinction of classical aversive conditioning in the rat. European Journal of Neuroscience 10 (3) , pp. 1019-1026. 10.1046/j.1460-9568.1998.00119.x

Hall, F. S., Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 and Robbins, T. W. 1997. The effects of isolation-rearing on preference by rats for a novel environment. Physiology & Behavior 62 (2) , pp. 299-303. 10.1016/S0031-9384(97)00117-0

Hall, F. S., Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 and Robbins, T. W. 1997. The effects of isolation-rearing on sucrose consumption in rats. Physiology & Behavior 62 (2) , pp. 291-297. 10.1016/S0031-9384(97)00116-9

Hall, F. S., Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 and Robbins, T. W. 1997. The effects of isolation-rearing of rats on behavioural responses to food and environmental novelty. Physiology & Behavior 62 (2) , pp. 281-290. 10.1016/S0031-9384(97)00115-7

Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124, Dias, R, Thomas, K.L, Augood, S.J, Everitt, B.J, Robbins, T.W and Roberts, A.C 1997. Contrasting effects of excitotoxic lesions of the prefrontal cortex on the behavioural response to d-amphetamine and presynaptic and postsynaptic measures of striatal dopamine function in monkeys. Neuroscience 80 (3) , pp. 717-730. 10.1016/S0306-4522(97)00075-4

Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 1997. The nature of interactions involving prefrontal and striatal dopamine systems. Journal of Psychopharmacology 11 (2) , pp. 143-150. 10.1177/026988119701100207

Matthews, K, Hall, FS, Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 and Robbins, TW 1996. Retarded acquisition and reduced expression of conditioned locomotor activity in adult rats following repeated early maternal separation: Effects of prefeeding, d-amphetamine, dopamine antagonists and clonidine. Psychopharmacology 126 (1) , pp. 75-84.

Humby, T, Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124, Robbins, TW and Geyer, MA 1996. Prepulses inhibit startle-induced reductions of extracellular dopamine in the nucleus accumbens of rat. Journal of Neuroscience 16 (6) , pp. 2149-2156.

Robbins, T.W., Jones, G.H. and Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 1996. Behavioural and neurochemical effects of early social deprivation in the rat. Journal of Psychopharmacology 10 (1) , pp. 39-47. 10.1177/026988119601000107

Matthews, Keith, Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 and Robbins, Trevor W. 1996. Repeated maternal separation of preweanling rats attenuates behavioral responses to primary and conditioned incentives in adulthood. Physiology & Behavior 59 (1) , pp. 99-107. 10.1016/0031-9384(95)02069-1

Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799, Robbins, T. W. and Everitt, B. J. 1995. Differential Effects of Forebrain 5-Hydroxytryptamine Depletions on Pavlovian Aversive Conditioning to Discrete and Contextual Stimuli in the Rat. European Journal of Neuroscience 7 (10) , pp. 2042-2052. 10.1111/j.1460-9568.1995.tb00627.x

Geyer, M. A., Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124, Humby, Trevor ORCID: https://orcid.org/0000-0002-1840-1799 and Robbins, T. W. 1995. Prepulse inhibition of startle-induced reductions of accumbens dopamine [Abstract]. Biological Psychiatry 37 (9) , p. 634. 10.1016/0006-3223(95)94560-J

McAlonan, Gráinne M., Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124, Robbins, Trevor W. and Everitt, Barry J. 1995. The effects of AMPA-induced lesions of the septo-hippocampal cholinergic projection on aversive conditioning to explicit and contextual cues and spatial learning in the water maze. European Journal of Neuroscience 7 (2) , pp. 281-292. 10.1111/j.1460-9568.1995.tb01064.x

Torres, E. M., Perry, T. A., Blokland, A., Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124, Wiley, R. G., Lappi, D. A. and Dunnett, Stephen Bruce ORCID: https://orcid.org/0000-0003-1826-1578 1994. Behavioural, histochemical and biochemical consequences of selective immunolesions in discrete regions of the basal forebrain cholinergic system. Neuroscience 63 (1) , pp. 95-122. 10.1016/0306-4522(94)90010-8

Phillips, G. D., Howes, S. R., Whitelaw, R. B., Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124, Robbins, T. W. and Everitt, B. J. 1994. Isolation rearing enhances the locomotor response to cocaine and a novel environment, but impairs the intravenous self-administration of cocaine. Psychopharmacology 115 (3) , pp. 407-418.

Roberts, A. C., De Salvia, M. A., Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124, Collins, P., Muir, J. L., Everitt, B. J. and Robbins, T. W. 1994. 6-Hydroxydopamine lesions of the prefrontal cortex in monkeys enhance performance on an analog of the Wisconsin Card Sort Test: possible interactions with subcortical dopamine. Journal of Neuroscience 14 (5) , pp. 2531-2544.

Marston, H. M., West, H. L., Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124, Everitt, B. J. and Robbins, T. W. 1994. Effects of excitotoxic lesions of the septum and vertical limb nucleus of the diagonal band of Broca on conditional visual discrimination: relationship between performance and choline acetyltransferase activity in the cingulate cortex. Journal of Neuroscience 14 (4) , pp. 2009-2019.

Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124, Killcross, Simon S., Humby, Trevor, Hall, Frank S., Geyer, Mark A. and Robbins, Trevor W. 1994. Social isolation in the rat produces developmentally specific deficits in prepulse inhibition of the acoustic startle response without disrupting latent inhibition. Neuropsychopharmacology 10 (1) , pp. 61-72. 10.1038/npp.1994.8

Geyer, Mark A., Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124, Humby, Trevor and Robbins, Trevor W. 1993. Isolation rearing of rats produces a deficit in prepulse inhibition of acoustic startle similar to that in schizophrenia. Biological psychiatry 34 (6) , pp. 361-372. 10.1016/0006-3223(93)90180-L

Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124, Mittleman, G., Torres, E., Humby, T., Hall, F. S. and Robbins, T. W. 1993. Enhancement of amphetamine-induced locomotor activity and dopamine release in nucleus accumbens following excitotoxic lesions of the hippocampus. Behavioural Brain Research 55 (2) , pp. 143-150.

Calamandrei, Gemma, Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 and Keverne, Eric B. 1992. Olfactory recognition of infants in laboratory mice: Role of noradrenergic mechanisms. Physiology & Behavior 52 (5) , pp. 901-907. 10.1016/0031-9384(92)90369-D

Page, K. J., Everitt, B. J., Robbins, T. W., Marston, H. M. and Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 1991. Dissociable effects on spatial maze and passive avoidance acquisition and retention following AMPA- and ibotenic acid-induced excitotoxic lesions of the basal forebrain in rats: Differential dependence on cholinergic neuronal loss. Neuroscience 43 (2-3) , pp. 457-472. 10.1016/0306-4522(91)90308-B

Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 and Collard, Keith J. 1990. Synaptosomal tryptophan uptake and efflux following lesion of central 5-hydroxytryptaminergic neurones. British Journal of Pharmacology 101 (4) , pp. 981-985. 10.1111/j.1476-5381.1990.tb14192.x

Foster, G. A., Roberts, M. H. T., Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124, Björklund, A., Gage, F. H., Hökfelt, T., Schultzberg, M. and Sharp, T. 1989. Structural and functional analysis of raphe neurone implants into denervated rat spinal cord. Brain Research Bulletin 22 (1) , pp. 131-137. 10.1016/0361-9230(89)90137-8

Davies, Michael, Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 and Roberts, Malcolm H.T. 1988. Evidence for depressant 5-HT1-like receptors on rat brainstem neurones. British Journal of Pharmacology 94 (2) , pp. 492-499. 10.1111/j.1476-5381.1988.tb11552.x

Davies, Michael, Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 and Roberts, Malcolm H.T. 1988. Evidence for excitatory 5-HT2-receptors on rat brainstem neurones. British Journal of Pharmacology 94 (2) , pp. 483-491. 10.1111/j.1476-5381.1988.tb11551.x

Collard, K.J., Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 and Lewis, D.J. 1988. Studies on the mechanism by which tryptophan efflux from isolated synaptosomes is stimulated by depolarization. British Journal of Pharmacology 93 (2) , pp. 341-348. 10.1111/j.1476-5381.1988.tb11440.x

Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 and Collard, Keith J. 1984. Opposite effects of extracellular sodium removal on the uptake of tryptophan into rat cortical slices and synaptosomes. Journal of Neuroscience 43 (1) , pp. 274-275. 10.1111/j.1471-4159.1984.tb06708.x

Collard, K. J., Evans, T. N. W., Suter, H. A. and Wilkinson, Lawrence Stephen ORCID: https://orcid.org/0000-0002-9337-6124 1982. The stimulus-induced release of 5-hydroxytryptamine and tryptophan from superfused rat brain synaptosomes. Journal of Neural Transmission 53 (2-3) , pp. 223-230. 10.1007/BF01243414