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Number of items: 60.

Rastogi, Namrata, Gonzalez, Juan Bautista Menendez, Srivastava, Vikas, Alanazi, Bader, Alanazi, Rehab N., Hughes, Owen M., O'Neill, Niamh S., Gilkes, Amanda, Ashley, Neil, Deshpande, Sumukh, Andrews, Robert, Mead, Adam, Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Darley, Richard ORCID: https://orcid.org/0000-0003-0879-0724 and Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 2023. Nuclear factor I-C overexpression promotes monocytic development and cell survival in acute myeloid leukemia. Leukemia 37 , pp. 276-287. 10.1038/s41375-022-01801-z
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Wagstaff, Megan, Tsaponina, Olga, Caalim, Gilian, Greenfield, Hayley, Milton-Harris, Leanne, Mancini, Erika J., Blair, Allison, Heesom, Kate J., Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976, Darley, Richard L. ORCID: https://orcid.org/0000-0003-0879-0724, Roberts, Stefan G. and Morgan, Rhys G. 2023. Crosstalk between β-catenin and WT1 signalling activity in acute myeloid leukemia [Letters to the Editor]. Haematologica 108 (1) 10.3324/haematol.2021.280294
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Morgan, Huw J., Rees, Elise, Lanfredini, Simone ORCID: https://orcid.org/0000-0002-3160-5120, Powell, Kate A., Gore, Jasmine, Gibbs, Alex, Lovatt, Charlotte, Davies, Gemma E., Olivero, Carlotta ORCID: https://orcid.org/0000-0002-8961-6703, Shorning, Boris Y., Tornillo, Giusy, Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976, Darley, Richard ORCID: https://orcid.org/0000-0003-0879-0724, Wang, Eddie C.Y. ORCID: https://orcid.org/0000-0002-2243-4964 and Patel, Girish K. 2022. CD200 ectodomain shedding into the tumor microenvironment leads to NK cell dysfunction and apoptosis. Journal of Clinical Investigation 132 (21) , e150750. 10.1172/JCI150750
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Menezes, Ana Catarina, Jones, Rachel, Shrestha, Alina, Nicholson, Rachael, Leckenby, Adam, Azevedo, Aleksandra, Davies, Sara, Baker, Sarah ORCID: https://orcid.org/0000-0002-7474-9757, Gilkes, Amanda, Darley, Richard ORCID: https://orcid.org/0000-0003-0879-0724 and Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 2022. Increased expression of RUNX3 inhibits normal human myeloid development. Leukemia 36 , pp. 1769-1780. 10.1038/s41375-022-01577-2
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Nicholson, Rachael, Menezes, Ana C., Azevedo, Aleksandra, Leckenby, Adam, Davies, Sara, Seedhouse, Claire, Gilkes, Amanda, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 and Darley, Richard L. ORCID: https://orcid.org/0000-0003-0879-0724 2022. Protein kinase C epsilon overexpression is associated with poor patient outcomes in AML and promotes daunorubicin resistance through p-glycoprotein-mediated drug efflux. Frontiers in Oncology 12 , 840046. 10.3389/fonc.2022.840046
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Menezes, Ana Catarina, Dixon, Christabel, Scholz, Anna, Nicholson, Rachael, Leckenby, Adam, Azevedo, Aleksandra, Baker, Sarah ORCID: https://orcid.org/0000-0002-7474-9757, Gilkes, Amanda F., Davies, Sara, Darley, Richard L. ORCID: https://orcid.org/0000-0003-0879-0724 and Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 2022. RUNX3 overexpression inhibits normal human erythroid development. Scientific Reports 12 , 1243. 10.1038/s41598-022-05371-z
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Robinson, Andrew J., Darley, Richard L. ORCID: https://orcid.org/0000-0003-0879-0724 and Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 2021. Reactive oxygen species in leukemias: maintaining cancer cell proliferation via redox signaling and changing metabolic homeostasis. Oncotarget 12 (10) , pp. 952-954. 10.18632/oncotarget.27913
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Rastogi, Namrata, Baker, Sarah ORCID: https://orcid.org/0000-0002-7474-9757, Man, Stephen ORCID: https://orcid.org/0000-0001-9103-1686, Uger, Robert A., Wong, Mark, Coles, Steve J., Hodges, Marie, Gilkes, Amanda, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Darley, Richard ORCID: https://orcid.org/0000-0003-0879-0724 and Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 2021. Use of an anti-CD200 blocking antibody improves immune responses to AML in vitro and in vivo. British Journal of Haematology 193 (1) , pp. 155-159. 10.1111/bjh.17125
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Robinson, Andrew J., Darley, Richard L. ORCID: https://orcid.org/0000-0003-0879-0724 and Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 2021. Reactive oxygen species and metabolic re-wiring in acute leukemias. Piccaluga, Pier Paolo, ed. Acute Leukemias, IntechOpen, pp. 35-56. (10.5772/intechopen.94829)
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Robinson, Andrew J., Hopkins, Goitseone L., Rastogi, Namrata, Hodges, Marie, Doyle, Michelle, Davies, Sara, Hole, Paul S., Omidvar, Nader, Darley, Richard L. ORCID: https://orcid.org/0000-0003-0879-0724 and Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 2020. Reactive oxygen species drive proliferation in acute myeloid leukemia via the glycolytic regulator PFKFB3. Cancer Research 80 (5) , pp. 937-949. 10.1158/0008-5472.CAN-19-1920
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Alanazi, Bader, Munje, Chinmay R., Rastogi, Namrata, Williamson, Andrew J. K., Taylor, Samuel, Hole, Paul S., Hodges, Marie, Doyle, Michelle, Baker, Sarah ORCID: https://orcid.org/0000-0002-7474-9757, Gilkes, Amanda F., Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Pierce, Andrew, Whetton, Anthony D., Darley, Richard L. ORCID: https://orcid.org/0000-0003-0879-0724 and Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 2020. Integrated nuclear proteomics and transcriptomics identifies S100A4 as a therapeutic target in acute myeloid leukemia. Leukemia 34 (2) , pp. 427-440. 10.1038/s41375-019-0596-4
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Morgan, Rhys G, Ridsdale, Jenna, Payne, Megan, Heesom, Kate J, Wilson, Marieangela C, Davidson, Andrew, Greenhough, Alexander, Davies, Sara, Williams, Ann C, Blair, Allison, Waterman, Marian L, Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 and Darley, Richard L ORCID: https://orcid.org/0000-0003-0879-0724 2019. LEF-1 drives aberrant B-catenin nuclear localization in myeloid leukemia cells. Haematologica 104 , pp. 1365-1377. 10.3324/haematol.2018.202846
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Wadley, Alex J., Morgan, Rhys G., Darley, Richard L. ORCID: https://orcid.org/0000-0003-0879-0724, Hole, Paul S. and Coles, Steven J. 2019. Using flow cytometry to detect and measure intracellular thiol redox status in viable T cells from heterogeneous populations. Hancock, John T. and Conway, Myra E., eds. Redox-Mediated Signal Transduction: Methods and Protocols, Vol. 1990. Methods in Molecular Biology, New York, NY, USA: Humana Press, pp. 53-70. (10.1007/978-1-4939-9463-2_5)

Munje, Chinmay, Hills, Robert K. ORCID: https://orcid.org/0000-0003-0166-0062, Whetton, Anthony, Burnett, Alan K., Darley, Richard L. ORCID: https://orcid.org/0000-0003-0879-0724 and Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 2015. Cord blood-derived quiescent CD34+ cells are more transcriptionally matched to AML blasts than cytokine-induced normal human hematopoietic CD34+ cells. Gene Expression: International Journal of Molecular and Cellular Science 16 (4) , pp. 169-175. 10.3727/105221615X14399878166159
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Coles, S. J., Gilmour, M. N., Reid, R., Knapper, S. ORCID: https://orcid.org/0000-0002-6405-4441, Burnett, A. K., Man, S. ORCID: https://orcid.org/0000-0001-9103-1686, Tonks, A. ORCID: https://orcid.org/0000-0002-6073-4976 and Darley, R. L. ORCID: https://orcid.org/0000-0003-0879-0724 2015. The immunosuppressive ligands PD-L1 and CD200 are linked in AML T-cell immunosuppression: identification of a new immunotherapeutic synapse. Leukemia 29 , pp. 1952-1954. 10.1038/leu.2015.62

Agathanggelou, A., Weston, V. J., Perry, T., Davies, N. J., Skowronska, A., Payne, D. T., Fossey, J. S., Oldreive, C. E., Wei, W., Pratt, G., Parry, H., Oscier, D., Coles, Steven, Hole, Paul Spencer, Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724, McMahon, M., Hayes, J. D., Moss, P., Stewart, G., Taylor, A. M. R. and Stankovic, T. 2015. Targeting the ataxia telangiectasia mutated-null phenotype in chronic lymphocytic leukemia with pro-oxidants. Haematologica 100 (8) , pp. 1076-1085. 10.3324/haematol.2014.115170

Morgan, Rhys G., Ridsdale, Jenna, Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 2014. Factors affecting the nuclear localization of β-Catenin in normal and malignant tissue. Journal of Cellular Biochemistry 115 (8) , pp. 1351-1361. 10.1002/jcb.24803

Zabkiewicz, Joanna ORCID: https://orcid.org/0000-0003-0951-3825, Pearn, Lorna, Hills, Robert ORCID: https://orcid.org/0000-0003-0166-0062, Morgan, Rhys G., Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976, Burnett, Alan K. and Darley, Richard ORCID: https://orcid.org/0000-0003-0879-0724 2014. The PDK1 master kinase is over-expressed in acute myeloid leukemia and promotes PKC-mediated survival of leukemic blasts. Haematologica 99 (5) , pp. 858-864. 10.3324/haematol.2013.096487

Hole, Paul Spencer, Zabkiewicz, Joanna ORCID: https://orcid.org/0000-0003-0951-3825, Munje, Chinmay, Newton, Zarabeth, Pearn, Lorna, White, Paul Charles ORCID: https://orcid.org/0000-0002-6562-4696, Marquez, Nuria, Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062, Burnett, Alan Kenneth, Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 2013. Overproduction of NOX-derived ROS in AML promotes proliferation and is associated with defective oxidative stress signaling. Blood 122 (19) , pp. 3322-3330. 10.1182/blood-2013-04-491944

Morgan, Rhys G., Pearn, Lorna, Liddiard, Kate ORCID: https://orcid.org/0000-0002-0953-1997, Pumford, Sara Louise, Burnett, Alan Kenneth, Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 2013. γ-Catenin is overexpressed in acute myeloid leukemia and promotes the stabilization and nuclear localization of β-catenin. Leukemia 27 (2) , pp. 336-343. 10.1038/leu.2012.221
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Daud, Siti Sarah, Pumford, Sara L, Gilmour, Marie N., Gilkes, Amanda F., Burnett, Alan Kenneth, Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062, Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 2012. Identification of the Wnt signalling protein, TCF7L2 as a significantly overexpressed transcription factor in AML [Abstract]. Blood 120 (21) , 1281.

Coles, Steven, Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Burnett, Alan Kenneth, Man, Stephen Tzekwung ORCID: https://orcid.org/0000-0001-9103-1686, Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 and Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 2012. Increased CD200 expression in acute myeloid leukemia is linked with an increased frequency of FoxP3+ regulatory T cells [Letter]. Leukemia 26 (9) , pp. 2146-2148. 10.1038/leu.2012.75
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Coles, Steven, Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Burnett, Alan Kenneth, Man, Stephen Tzekwung ORCID: https://orcid.org/0000-0001-9103-1686, Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 and Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 2012. Expression of CD200 on AML blasts directly suppresses memory T-cell function [Letter]. Leukemia 26 (9) , pp. 2148-2151. 10.1038/leu.2012.77

Liddiard, Kate ORCID: https://orcid.org/0000-0002-0953-1997, Burnett, Alan Kenneth, Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 and Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 2012. RUNX1-ETO deregulates the proliferation and growth factor responsiveness of human hematopoietic progenitor cells downstream of the myeloid transcription factor, MYCT1 [Letter]. Leukemia 26 (1) , pp. 177-179. 10.1038/leu.2011.188
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Coles, Steven, Man, Stephen Tzekwung ORCID: https://orcid.org/0000-0001-9103-1686, Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062, Wang, Edward Chyng Yern ORCID: https://orcid.org/0000-0002-2243-4964, Burnett, Alan Kenneth, Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 and Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 2011. CD200 inhibits memory Th1 cell function in acute myeloid leukaemia (AML)[Abstract]. Immunology 135 (S1) , p. 178. 10.1111/j.1365-2567.2011.03534.x

Coles, Steven, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Man, Stephen Tzekwung ORCID: https://orcid.org/0000-0001-9103-1686, Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062, Burnett, Alan Kenneth, Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 2011. CD200 expression suppresses natural killer cell function and directly inhibits patient anti-tumor response in acute myeloid leukemia. Leukemia 25 (5) , pp. 792-799. 10.1038/leu.2011.1

Hole, Paul Spencer, Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 and Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 2011. Do reactive oxygen species play a role in myeloid leukemias? Blood 117 (22) , pp. 5816-5826. 10.1182/blood-2011-01-326025

Zabkiewicz, Joanna ORCID: https://orcid.org/0000-0003-0951-3825, Pearn, Lorna, Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062, Morgan, Rhys G., Burnett, Alan Kenneth, Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 2010. PDK1 overexpression in acute myeloid leukemia; Clinical significance and potential as a therapeutic target [Abstract]. Blood 116 (21) , pp. 892-893.

Morgan, Rhys Gareth, Pearn, Lorna, Liddiard, Kate ORCID: https://orcid.org/0000-0002-0953-1997, Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062, Burnett, Alan Kenneth, Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 2010. Distinct regulation of beta- and gamma-Catenin throughout hematopoietic development contrasts with their cooperative roles in acute myeloid leukemia [Abstract]. Blood 116 (21) , 1573.

Coles, Steven, Man, Stephen Tzekwung ORCID: https://orcid.org/0000-0001-9103-1686, Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Burnett, Alan Kenneth, Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 and Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 2010. Over-expression of CD200 un acute myeloid leukemia mediates the expansion of regulatory T-lymphocytes and directly inhibits natural killer cell tumor immunity [Abstract]. Blood 116 (21) , p. 218.

Liddiard, Kate ORCID: https://orcid.org/0000-0002-0953-1997, Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062, Burnett, Alan Kenneth, Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 and Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 2010. OGG1 is a novel prognostic indicator in acute myeloid leukaemia. Oncogene 29 (13) , pp. 2005-2012. 10.1038/onc.2009.462

Hole, Paul Spencer, Pearn, Lorna, Tonks, Amanda Jayne ORCID: https://orcid.org/0000-0002-6073-4976, James, Philip Eurig, Burnett, Alan Kenneth, Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 and Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 2010. Ras-induced reactive oxygen species promote growth factor-independent proliferation in human CD34+ hematopoietic progenitor cells. Blood 115 (6) , pp. 1238-1246. 10.1182/blood-2009-06-222869

Yang, Jian ORCID: https://orcid.org/0000-0003-2631-4553, Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724, Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X and Evans, William Howard 2009. Low connexin channel-dependent intercellular communication in human adult hematopoietic progenitor/stem cells: Probing mechanisms of autologous stem cell therapy. Cell Communication and Adhesion 16 (5-6) , pp. 138-145. 10.3109/15419061003653763

Dewitt, Sharon ORCID: https://orcid.org/0000-0001-8169-8241, Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 and Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X 2009. Translocation or just location? Pseudopodia affect fluorescent signals. Journal of Cell Biology 184 (2) , pp. 197-203. 10.1083/jcb.200806047
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Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976, Pearn, Lorna, Musson, Megan, Gilkes, Amanda F., Mills, Kenneth Ian, Burnett, Alan Kenneth and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 2007. Transcriptional dysregulation mediated by RUNX1-RUNX1T1 in normal human progenitor cells and in acute myeloid leukaemia. Leukemia 21 (12) , pp. 2495-2505. 10.1038/sj.leu.2404961

Walsby, Elisabeth Jane ORCID: https://orcid.org/0000-0001-8523-5017, Gilkes, Amanda Frances, Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976, Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 and Mills, Kenneth Ian 2007. FUS expression alters the differentiation response to all-trans retinoic acid in NB4 and NB4R2 cells. British Journal of Haematology 139 (1) , pp. 94-97. 10.1111/j.1365-2141.2007.06756.x

Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976, Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062, White, Paul Charles ORCID: https://orcid.org/0000-0002-6562-4696, Rosie, B., Mills, Kenneth Ian, Burnett, Alan Kenneth and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 2007. CD200 as a prognostic factor in acute myeloid leukaemia. Leukemia 21 (3) , pp. 566-568. 10.1038/sj.leu.2404559

Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976, Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062, White, Paul Charles ORCID: https://orcid.org/0000-0002-6562-4696, Rosie, B., Mills, Kenneth Ian, Burnett, Alan Kenneth and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 2007. CD200 as a prognostic factor in acute myeloid leukaemia [Letter]. Leukemia 21 (3) , pp. 566-568. 10.1038/sj.leu.2404559

Pearn, Lorna, Fisher, Janet, Burnett, Alan Kenneth and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 2007. The role of PKC and PDK1 in monocyte lineage specification by Ras. Blood 109 (10) , pp. 4461-9. 10.1182/blood-2006-09-047217

Omidvar, Nader, Pearn, Lorna, Burnett, Alan Kenneth and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 2006. Ral is both necessary and sufficient for the inhibition of myeloid differentiation mediated by Ras. Molecular and cellular biology 26 (10) , pp. 3966-75. 10.1128/MCB.26.10.3966-3975.2006
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Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976, Pearn, Lorna, Mills, Kenneth Ian, Burnett, Alan Kenneth and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 2006. The sensitivity of human cells expressing RUNX1-RUNX1T1 to chemotherapeutic agents. Leukemia 20 (10) , pp. 1883-5. 10.1038/sj.leu.2404364

Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976, Tonks, Amanda Jayne ORCID: https://orcid.org/0000-0002-6073-4976, Pearn, Lorna, Mohamad, Zulkhairi, Burnett, Alan Kenneth and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 2005. Optimized retroviral transduction protocol which preserves the primitive subpopulation of human hematopoietic cells. Biotechnology Progress 21 (3) , pp. 953-958. 10.1021/bp0500314

Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976, Tonks, Amanda Jayne, Pearn, Lorna, Pearce, Laurence, Hoy, Terence George, Couzens, Stephen, Fisher, Janet, Burnett, Alan Kenneth and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 2004. Expression of AML1-ETO in human myelomonocytic cells selectively inhibits granulocytic differentiation and promotes their self-renewal. Leukemia 18 (7) , pp. 1238-1245. 10.1038/sj.leu.2403396

Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976, Tonks, Amanda Jayne, Pearn, Lorna, Pearce, L., Hoy, T., Couzens, Stephen, Fisher, J., Burnett, Alan Kenneth and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 2004. Expression of AML1-ETO in human myelomonocytic cells selectively inhibits granulocytic differentiation and promotes their self-renewal. Leukemia 18 (7) , pp. 1238-1245. 10.1038/sj.leu.2403396

Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976, Pearn, Lorna, Tonks, Amanda Jayne, Pearce, Laurence, Hoy, Terence George, Phillips, Sarah, Fisher, Janet, Downing, James R., Burnett, Alan Kenneth and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 2003. The AML-1 ETO fusion gene promotes extensive self-renewal of human primary erythroid cells. Blood 101 (2) , pp. 624-632. 10.1182/blood-2002-06-1732

Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724, Pearn, Lorna, Omidvar, Nader, Sweeney, Marion Carol ORCID: https://orcid.org/0000-0003-0713-0855, Fisher, Janet, Phillips, Sarah, Hoy, Terence George and Burnett, Alan Kenneth 2002. Protein kinase C mediates mutant N-Ras-induced developmental abnormalities in normal human erythroid cells. Blood 100 (12) , pp. 4185-92. 10.1182/blood-2002-05-1358

McGlynn, Angela P., Padua, Rose Ann, Burnett, Alan Kenneth and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 2000. Alternative effects of RAS and RAF oncogenes on the proliferation and apoptosis of factor-dependent FDC-P1 cells. Leukemia Research 24 (1) , pp. 47-54. 10.1016/s0145-2126(99)00159-9

Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724, Pearn, Lorna and Burnett, Alan Kenneth 2000. Mutant RAS promotes amplification of primitive human erythroid cells. Blood 96 (11) , 92A-92A.

Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 and Burnett, Alan Kenneth 1999. Mutant RAS inhibits neutrophil but not macrophage differentiation and allows continued growth of neutrophil precursors. Experimental Hematology 27 (11) , pp. 1599-1608. 10.1016/S0301-472X(99)00100-9

Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724, Hoy, T. G., Robinson, L. and Burnett, Alan Kenneth 1998. Mutant N-RAS blocks granulocytic differentiation of human cd34+ cells. British Journal of Haematology 102 (1) , p. 289. 10.1111/j.1365-2141.1998.tb08997.x

Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724, Hoy, T. G. and Burnett, Alan Kenneth 1998. Mutant N-RAS blocks granulocytic differentiation of human CD34(+) cells [Abstract]. British Journal of Haematology 101 (S) , p. 22.

Gallagher, Andrea P., Burnett, Alan Kenneth, Bowen, David T. and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 1998. Mutant RAS selectively promotes sensitivity of myeloid leukemia cells to apoptosis by a protein kinase C-dependent process. Cancer Research 58 (9) , pp. 2029-2035.

Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724, Gallagher, A. P., Bowen, D. T. and Burnett, Alan Kenneth 1997. Mutant RAS selectively promotes sensitivity of myeloid leukemia cells to apoptosis by a PKC-dependent process. Blood 90 (10) , p. 202.

Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724, Hoy, Terence G., Baines, Paul, Padua, Rose Ann and Burnett, Alan Kenneth 1997. Mutant N-RAS induces erythroid lineage dysplasia in human CD34+ Cells. Journal of Experimental Medicine 185 (7) , pp. 1337-1348. 10.1084/jem.185.7.1337

Zaker, Farhad, Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724, Sabah, Ala Al and Burnett, Alan Kenneth 1997. Oncogenic RAS genes impair erythroid differentiation of erythroleukaemia cells. Leukemia Research 21 (7) , pp. 635-640. 10.1016/S0145-2126(97)00022-2

Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724, Baines, Paul, Hoy, Terence G., Padua, Rose Ann and Burnett, Alan Kenneth 1996. Mutant N-RAS alters the developmental potential of human CD34(+) cells in a lineage-specific manner. British Journal of Haematology 93 (S2) , p. 597.

Evely, R. S., Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724, Gilkes, Amanda F., Goringe, A., Mirza, T. and Burnett, Alan Kenneth 1996. In-vivo modelling of myeloid malignancies using severe combined immunodeficient (SCID) mice [Abstract]. British Journal of Haematology 93 , p. 205.

Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724, Baines, Paul, Hoy, T. G. and Burnett, Alan Kenneth 1995. Mutant N-RAS induces erythroid lineage dysplasia in human CD34(+) progenitor cells. Blood 86 (10) , p. 1665.

Gallagher, A., Padua, R. A., Alsabah, A., Burnett, Alan Kenneth and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 1994. P21RAS expression in leukemogenesis and hematopoiesis. Blood 84 (10) , A605-A605.

Morris, Alan G., Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 and Bateman, Wendy J. 1992. The loss of class II MHC antigen expression by ras-transformed murine fibroblasts passaged as tumours correlates with increased tumorigenicity but is not mediated by T cells. Cancer Immunology, Immunotherapy 35 (1) , pp. 46-52. 10.1007/BF01741054

This list was generated on Sat Nov 8 11:29:58 2025 GMT.


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