Almotiri, Alhomidi, Abdelfattah, Ali, Storch, Elis, Stemmler, Marc P., Brabletz, Simone, Brabletz, Thomas and Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733 2024. Zeb1 maintains long-term adult hematopoietic stem cell function and extramedullary hematopoiesis. Experimental Hematology 134 , 104177. 10.1016/j.exphem.2024.104177 |
Almotiri, Alhomidi, Boyd, Ashleigh S. and Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733 2023. Zeb1 Regulates the function of lympho-myeloid primed progenitors after transplantation. Biomolecules 13 (9) , 1386. 10.3390/biom13091386 |
Chan, Yee-Hung, Moss, Joe W. E. ORCID: https://orcid.org/0000-0002-1866-9752, Williams, Jessica O., Ferekidis, Nele, Alshehri, Nouf, Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490, Menendez Gonzalez, Juan B., Plummer, Sue F., Michael, Daryn R., Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733 and Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578 2023. (+)-catechin attenuates multiple atherosclerosis-associated processes in vitro, modulates disease-associated risk factors in C57BL/6J mice and reduces atherogenesis in LDL receptor deficient mice by inhibiting inflammation and increasing markers of plaque stability. Molecular Nutrition & Food Research 67 (14) , 2200716. 10.1002/mnfr.202200716 |
Rastogi, Namrata, Gonzalez, Juan Bautista Menendez, Srivastava, Vikas, Alanazi, Bader, Alanazi, Rehab N., Hughes, Owen M., O'Neill, Niamh S., Gilkes, Amanda, Ashley, Neil, Deshpande, Sumukh, Andrews, Robert, Mead, Adam, Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Darley, Richard ORCID: https://orcid.org/0000-0003-0879-0724 and Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 2023. Nuclear factor I-C overexpression promotes monocytic development and cell survival in acute myeloid leukemia. Leukemia 37 , pp. 276-287. 10.1038/s41375-022-01801-z |
Menendez-Gonzalez, Juan Bautista, Strange, Kathryn E., Bassetto, Marcella, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733 and Ferla, Salvatore 2022. Ligand-based discovery of a novel GATA2 inhibitor targeting acute myeloid leukemia cells. Frontiers In Drug Discovery 2 , 1013229. 10.3389/fddsv.2022.1013229 |
Menendez-Gonzalez, Juan Bautista and Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733 2022. Exploring the associations between clonal hematopoiesis of indeterminate potential, myeloid malignancy, and atherosclerosis. Ramji, Dipak, ed. Atherosclerosis, Vol. 2419. Methods in Molecular Biology, Springer, pp. 73-88. (10.1007/978-1-0716-1924-7_5) |
Almotiri, Alhomidi, Abdelfattah, Ali and Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733 2022. Flow cytometry analysis of hematopoietic stem/progenitor cells and mature blood cell subsets in atherosclerosis. Ramji, Dipak, ed. Atherosclerosis, Vol. 2419. Methods in Molecular Biology, Springer, pp. 583-595. (10.1007/978-1-0716-1924-7_36) |
Lawson, Hannah, van de Lagemaat, Louie N., Barile, Melania, Tavosanis, Andrea, Durko, Jozef, Villacreces, Arnaud, Bellani, Aarushi, Mapperley, Christopher, Georges, Elise, Martins-Costa, Catarina, Sepulveda, Catarina, Allen, Lewis, Campos, Joana, Campbell, Kirsteen J., O'Carroll, Donal, Gottgens, Berthold, Cory, Suzanne, Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733, Guitart, Amelie V. and Kranc, Kamil R. 2021. CITED2 coordinates key haematopoietic regulatory pathways to maintain the HSC pool in both steady-state haematopoiesis and transplantation. Stem Cell Reports 16 (11) , pp. 2784-2797. 10.1016/j.stemcr.2021.10.001 |
Abdelfattah, Ali Mahmoud, Hughes-Davies, Antonia, Clayfield, Liam Daniel, Menendez-Gonzalez, Juan Bautista, Almotiri, Alhomidi, Alotaibi, Badi, Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 and Rodrigues, Neil P ORCID: https://orcid.org/0000-0002-1925-7733 2021. Gata2 haploinsufficiency promotes proliferation and functional decline of HSCs with myeloid bias during aging. Blood Advances 5 (20) , pp. 4285-4290. 10.1182/bloodadvances.2021004726 |
O'Morain, Victoria L., Chan, Yee-Hung, Williams, Jessica O., Alotibi, Reem, Alahmadi, Alaa, Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733, Plummer, Sue F., Hughes, Timothy R., Michael, Daryn R. and Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578 2021. The Lab4P consortium of probiotics attenuates atherosclerosis in LDL receptor deficient mice fed a high fat diet and causes plaque stabilization by inhibiting inflammation and several pro-atherogenic processes. Molecular Nutrition & Food Research 65 (17) , 2100214. 10.1002/mnfr.202100214 |
Moss, Joe W. E. ORCID: https://orcid.org/0000-0002-1866-9752, Williams, Jessica O., Al-Ahmadi, Wijdan, O'Morain, Victoria, Chan, Yee-Hung, Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490, Menendez-Gonzalez, Juan B., Almotiri, Alhomidi, Plummer, Sue F., Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733, Michael, D. R. and Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578 2021. Protective effects of a unique combination of nutritionally active ingredients on risk factors and gene expression associated with atherosclerosis in C57BL/6J mice fed a high fat diet. Food and Function 12 (8) , pp. 3657-3671. 10.1039/D0FO02867C |
Lawson, Hannah, Sepulveda, Catarina, van de Latemaat, Louie N., Durko, Jozef, Barile, Melania, Tavosanis, Andrea, Georges, Elise, Shmakova, Alena, Timms, Penny, Carter, Roderick N., Allen, Lewis, Campos, Joana, Vukovic, Milica, Guitart, Amelie V., Giles, Peter ORCID: https://orcid.org/0000-0003-3143-6854, O'Shea, Marie, Vernimmen, Douglas, Morton, Nicholas M., Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733, Gottgens, Berthold, Schofield, Christopher J., Lengeling, Andreas, O'Carroll, Donal and Kranc, Kamil R. 2021. JMJD6 promotes self-renewal and regenerative capacity of hematopoietic stem cells. Blood Advances 5 (3) , pp. 889-899. 10.1182/bloodadvances.2020002702 |
Almotiri, Alhomidi, Alzahrani, Hamed Ahmad A., Menendez-Gonzalez, Juan Bautista, Abdelfattah, Ali, Alotaibi, Badi, Saleh, Lubaid, Greene, Adelle, Georgiou, Mia R. F., Gibbs, Alex, Alsayari, Amani Salem, Taha, Sarab, Thomas, Leigh-Anne, Shah, Dhruv, Edkins, Sarah ORCID: https://orcid.org/0000-0003-0717-1972, Giles, Peter J. ORCID: https://orcid.org/0000-0003-3143-6854, Stemmler, Marc P., Brabletz, Simone, Brabletz, Thomas, Boyd, Ashleigh S., Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775 and Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733 2021. Zeb1 modulates hematopoietic stem cell fates required for suppressing acute myeloid leukemia. Journal of Clinical Investigation 131 (1) , e129115. 10.1172/JCI129115 |
Menendez Gonzalez, Juan Bautista, Sinnadurai, Samantha, Gibbs, Alex, Thomas, Leigh-anne, Konstantinou, Maria, Garcia Valverde, Alfonso, Boyer, Magali, Wang, Zhengke, Boyd, Ashleigh S., Blair, Allison, Morgan, Rhys G. and Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733 2019. Inhibition of GATA2 restrains cell proliferation and enhances apoptosis and chemotherapy mediated apoptosis in human GATA2 overexpressing AML cells. Scientific Reports 9 , 12212. 10.1038/s41598-019-48589-0 |
Menendez Gonzalez, Juan Bautista, Vukovic, Milica, Abdelfattah, Ali, Saleh, Lubaid, Almotiri, Alhomidi, Thomas, Leigh-anne, Agirre-Lizaso, Alona, Azevedo, Aleksandra, Menezes, Ana Catarina, Tornillo, Giusy, Edkins, Sarah ORCID: https://orcid.org/0000-0003-0717-1972, Kong, Kay, Giles, Peter ORCID: https://orcid.org/0000-0003-3143-6854, Anjos-Afonso, Fernando, Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976, Boyd, Ashleigh S., Kranc, Kamil R. and Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733 2019. Gata2 as a crucial regulator of stem cells in adult hematopoiesis and acute myeloid leukemia. Stem Cell Reports 13 (2) , pp. 291-306. 10.1016/j.stemcr.2019.07.005 |
Menendez-Gonzalez, Juan Bautista, Saleh, Lubaid, Feng, Gui Jie and Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733 2019. Isolation of murine hematopoietic stem cells. Boyd, Ashleigh S., ed. Immunological Tolerance: Methods and Protocols, Vol. 1899. Methods in Molecular Biology, New York: Humana Press, pp. 15-23. (10.1007/978-1-4939-8938-6_2) |
Boyd, Ashleigh S. and Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733 2018. Stem cells cycle toward immune surveillance. Immunity 48 (2) , pp. 187-190. 10.1016/j.immuni.2018.02.006 |
Portero Migueles, Rosa, Shaw, Louise, Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733, May, Gillian, Henseleit, Korinna, Anderson, Kathryn G. V., Goker, Hakan, Jones, C. Michael, de Bruijn, Marella F. T. R., Brickman, Joshua M. and Enver, Tariq 2017. Transcriptional regulation of Hhex in hematopoiesis and hematopoietic stem cell ontogeny. Developmental Biology 424 (2) , pp. 236-245. 10.1016/j.ydbio.2016.12.021 |
Guitart, Amelie V, Panagopoulou, Theano I, Villacreces, Arnaud, Vukovic, Milica, Sepulveda, Catarina, Allen, Lewis, Carter, Roderick N, Lagemaat, Louie N van de, Morgan, Marcos, Giles, Peter, Sas, Zuzanna, Gonzalez, Marta Vila, Lawson, Hannah, Paris, Jasmin, Edwards-Hicks, Joy, Schaak, Katrin, Subramani, Chithra, Gezer, Deniz, Armesilla-Diaz, Alejandro, Wills, Jimi Carlo, Easterbrook, Aaron, Coman, David, Wai, Chi, So, Eric, O'Carroll, Donal, Vernimmen, Douglas, Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733, Pollard, Patrick J, Morton, Nicholas M, Finch, Andrew and Kranc, Kamil R 2017. Fumarate hydratase is a critical regulator of hematopoietic stem cell functions. Journal of Experimental Medicine 214 (3) , -. 10.1084/jem.20161087 |
Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733 and Tipping, A. J. 2013. Transcription factor GATA-2 regulates quiescence of hematopoietic stem and progenitor cells. Hayat, M. A., ed. Tumor Dormancy, Quiescence, and Senescence, Volume 2, Vol. 2. Springer, pp. 277-288. (10.1007/978-94-007-7726-2_26) |
Guha, Prajna, Morgan, John W., Mostoslavsky, Gustavo, Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733 and Boyd, Ashleigh S. 2013. Lack of immune response to differentiated cells derived from syngeneic induced pluripotent stem cells. Cell Stem Cell 12 (4) , pp. 407-412. 10.1016/j.stem.2013.01.006 |
Boyd, Ashleigh S., Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733, Lui, Kathy O., Fu, Xuemei and Xu, Yang 2012. Concise review: Immune recognition of induced pluripotent stem cells. Stem Cells 30 (5) , pp. 797-803. 10.1002/stem.1066 |
Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733, Tipping, Alex J., Wang, Zhengke and Enver, Tariq 2012. GATA-2 mediated regulation of normal hematopoietic stem/progenitor cell function, myelodysplasia and myeloid leukemia. The International Journal of Biochemistry & Cell Biology 44 (3) , pp. 457-460. 10.1016/j.biocel.2011.12.004 |
Kranc, Kamil R., Schepers, Hein, Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733, Bamforth, Simon, Villadsen, Ellen, Ferry, Helen, Bouriez-Jones, Tiphaine, Sigvardsson, Mikael, Bhattacharya, Shoumo, Jacobsen, Sten Eirik and Enver, Tariq 2009. Cited2 is an essential regulator of adult hematopoietic stem cells. Cell Stem Cell 5 (6) , pp. 659-665. 10.1016/j.stem.2009.11.001 |
Tipping, A. J., Pina, C., Castor, A., Hong, D., Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733, Lazzari, L., May, G. E., Jacobsen, S. E. W. and Enver, T. 2009. High GATA-2 expression inhibits human hematopoietic stem and progenitor cell function by effects on cell cycle. Blood 113 (12) , pp. 2661-2672. 10.1182/blood-2008-06-161117 |
Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733, Boyd, Ashleigh S., Fugazza, Cristina, May, Gillian E., Guo, YanPing, Tipping, Alex J., Scadden, David T., Vyas, Paresh and Enver, Tariq 2008. GATA-2 regulates granulocyte-macrophage progenitor cell function. Blood 112 (13) , pp. 4862-4873. 10.1182/blood-2008-01-136564 |
Nijnik, Anastasia, Woodbine, Lisa, Marchetti, Caterina, Dawson, Sara, Lambe, Teresa, Liu, Cong, Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733, Crockford, Tanya L., Cabuy, Erik, Vindigni, Alessandro, Enver, Tariq, Bell, John I., Slijepcevic, Predrag, Goodnow, Christopher C., Jeggo, Penelope A. and Cornall, Richard J. 2007. DNA repair is limiting for haematopoietic stem cells during ageing. Nature 447 (7145) , pp. 686-690. 10.1038/nature05875 |
Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733, Janzen, V., Forkert, R., Dombkowski, D. M., Boyd, A. S., Orkin, S. H., Enver, T., Vyas, P. and Scadden, D. 2005. Haploinsufficiency of GATA-2 perturbs adult hematopoietic stem-cell homeostasis. Blood 106 (2) , pp. 477-484. 10.1182/blood-2004-08-2989 |
Craiu, A., Saito, Y., Limon, A., Eppich, H. M., Olson, D. P., Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733, Adams, G. B., Dombkowski, D., Richardson, P., Schlossman, R., Choi, P. S., Grogins, J., O'Connor, P. G., Cohen, K., Attar, E. C., Freshman, J., Rich, R., Mangano, J. A., Gribben, J. G., Anderson, K. C. and Scadden, D. T. 2005. Flowing cells through pulsed electric fields efficiently purges stem cell preparations of contaminating myeloma cells while preserving stem cell function. Blood 105 (5) , pp. 2235-2238. 10.1182/blood-2003-12-4399 |
Qiu, J., Takagi, Y., Harada, J., Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733, Moskowitz, M. A., Scadden, D. T. and Cheng, T. 2004. Regenerative response in ischemic brain restricted by p21cip1/waf1. Journal of Experimental Medicine 199 (7) , pp. 937-945. 10.1084/jem.20031385 |
Adams, G. B., Chabner, K. T., Foxall, R. T., Weibrecht, K. W., Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733, Dombkowski, D., Fallon, R., Poznansky, M. C. and Scadden, D. T. 2002. Heterologous cells cooperate to augment stem cell migration, homing, and engraftment. Blood 101 (1) , pp. 45-51. 10.1182/blood-2002-02-0486 |
Cheng, T., Shen, H., Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733, Stier, S. and Scadden, D. T. 2001. Transforming growth factor β1 mediates cell-cycle arrest of primitive hematopoietic cells independent of p21Cip1/Waf1or p27Kip1. Blood 98 (13) , pp. 3643-3649. 10.1182/blood.V98.13.3643 |
Cheng, Tao, Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733, Shen, Hongmei, Yang, Yong-Guang, Dombkowski, David, Sykes, Megan and Scadden, David T. 2000. Hematopoietic stem cell quiescence maintained by p21cip1/waf1. Science 287 (5459) , pp. 1804-1808. 10.1126/science.287.5459.1804 |
Cheng, Tao, Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733, Dombkowski, David, Stier, Sebastian and Scadden, David T. 2000. Stem cell repopulation efficiency but not pool size is governed by p27 (kip1). Nature Medicine 6 , pp. 1235-1240. 10.1038/81335 |