Browse by Current Cardiff authors

Bentley, Kirsten ORCID: https://orcid.org/0000-0002-6619-2098, Statkute, Evelina, Murrell, Isa, Fielding, Ceri A. ORCID: https://orcid.org/0000-0002-5817-3153, Antrobus, Robin, Preston, Hannah, Kerr-Jones, Lauren, Cochrane, Daniel, Brizic, Ilija, Lehner, Paul J., Wilkinson, Gavin W. G., Wang, Eddie C. Y. ORCID: https://orcid.org/0000-0002-2243-4964, Graham, Stephen C., Weekes, Michael P. and Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182 2025. Virion proteomics of genetically intact HCMV reveals a regulator of envelope glycoprotein composition that protects against humoral immunity. Proceedings of the National Academy of Sciences 122 (38) , e2425622122. 10.1073/pnas.2425622122

Davies, Kate ORCID: https://orcid.org/0000-0002-9807-1231, Rizek, Al-Motaz, Edkins, Sarah ORCID: https://orcid.org/0000-0003-0717-1972, Kollnberger, Simon, Wang, Eddie C. Y. ORCID: https://orcid.org/0000-0002-2243-4964, Eberl, Matthias ORCID: https://orcid.org/0000-0002-9390-5348, Underwood, Jonathan ORCID: https://orcid.org/0000-0001-6963-2821 and Mclaren, James E. ORCID: https://orcid.org/0000-0002-7021-5934 2025. NKG2A-mediated immune modulation of natural killer cells by Staphylococcus aureus. The Journal of Immunology , vkaf174. 10.1093/jimmun/vkaf174 Item availability restricted.

Preston, Hannah, Casey, Rowan, Ferris, Elizabeth, Kerr-Jones, Lauren, Jones, Lauren, Latif, Farah ORCID: https://orcid.org/0000-0002-0576-9623, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Aicheler, Rebecca J., Wang, Eddie C. Y. ORCID: https://orcid.org/0000-0002-2243-4964, Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182 and Fielding, Ceri A. ORCID: https://orcid.org/0000-0002-5817-3153 2025. Human cytomegalovirus immune evasion of natural killer cells: a virus for all seasons? Pathogens 14 (7) , 629. 10.3390/pathogens14070629

Litvin, Ulad, Wang, Eddie C.Y. ORCID: https://orcid.org/0000-0002-2243-4964, Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182, Fielding, Ceri A. ORCID: https://orcid.org/0000-0002-5817-3153 and Hughes, Joseph 2024. Evolution of the cytomegalovirus RL11 gene family in old world monkeys and great apes. Virus Evolution 10 (1) , veae066. 10.1093/ve/veae066

Kite, Joanne, Hill, Monica, Preston, Natasha, Rubina, Anzelika, Kollnberger, Simon, Wang, Eddie Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 and Elliott, Gillian 2024. Downregulation of endogenous nectin1 in human keratinocytes by herpes simplex virus 1 glycoprotein D excludes superinfection but does not affect NK cell function. Journal of General Virology 105 (3) 10.1099/jgv.0.001969

Vlachava, Virginia-Maria ORCID: https://orcid.org/0000-0003-4233-7739, Seirafian, Sepehr, Fielding, Ceri A. ORCID: https://orcid.org/0000-0002-5817-3153, Kollnberger, Simon, Aicheler, Rebecca J., Hughes, Joseph, Baker, Alexander ORCID: https://orcid.org/0000-0001-8232-0531, Weekes, Michael P., Forbes, Simone, Wilkinson, Gavin W. G., Wang, Eddie C. Y. ORCID: https://orcid.org/0000-0002-2243-4964 and Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182 2023. HCMV-secreted glycoprotein gpUL4 inhibits TRAIL-mediated apoptosis and NK cell activation. Proceedings of the National Academy of Sciences 120 (49) , e2309077120. 10.1073/pnas.2309077120

Rubina, Anzelika, Patel, Mihil, Nightingale, Katie, Potts, Martin, Fielding, Ceri A. ORCID: https://orcid.org/0000-0002-5817-3153, Kollnberger, Simon, Lau, Betty, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Miners, Kelly L., Nichols, Jenna, Nobre, Luis, Roberts, Dawn, Trinca, Terrence M., Twohig, Jason P., Vlahava, Virginia-Maria, Davison, Andrew J., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Tomasec, Peter, Wilkinson, Gavin W. G., Weekes, Michael P., Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182 and Wang, Eddie C. Y. ORCID: https://orcid.org/0000-0002-2243-4964 2023. ADAM17 targeting by human cytomegalovirus remodels the cell surface proteome to simultaneously regulate multiple immune pathways. Proceedings of the National Academy of Sciences 120 (33) , e2303155120. 10.1073/pnas.2303155120

Grant, Michael D., Bentley, Kirsten ORCID: https://orcid.org/0000-0002-6619-2098, Fielding, Ceri A. ORCID: https://orcid.org/0000-0002-5817-3153, Hatfield, Keeley M., Ings, Danielle P., Harnum, Debbie, Wang, Eddie C.Y. ORCID: https://orcid.org/0000-0002-2243-4964, Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182 and Holder, Kayla A. 2023. Combined anti-S1 and anti-S2 antibodies from hybrid immunity elicit potent cross-variant ADCC against SARS-CoV-2. JCI Insight 8 (15) , e170681. 10.1172/jci.insight.170681

Luo, Shunqun, Liman, Nurcin, Li, Can, Crossman, Assiatu, Wang, Eddie C. Y. ORCID: https://orcid.org/0000-0002-2243-4964, Meylan, Françoise and Park, Jung-Hyun 2023. The cytokine receptor DR3 identifies and promotes the activation of thymic NKT17 cells. Cellular and Molecular Life Sciences 80 (3) , pp. 1-12. 10.1007/s00018-023-04726-7

Morgan, Huw J., Rees, Elise, Lanfredini, Simone ORCID: https://orcid.org/0000-0002-3160-5120, Powell, Kate A., Gore, Jasmine, Gibbs, Alex, Lovatt, Charlotte, Davies, Gemma E., Olivero, Carlotta ORCID: https://orcid.org/0000-0002-8961-6703, Shorning, Boris Y., Tornillo, Giusy, Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976, Darley, Richard ORCID: https://orcid.org/0000-0003-0879-0724, Wang, Eddie C.Y. ORCID: https://orcid.org/0000-0002-2243-4964 and Patel, Girish K. 2022. CD200 ectodomain shedding into the tumor microenvironment leads to NK cell dysfunction and apoptosis. Journal of Clinical Investigation 132 (21) , e150750. 10.1172/JCI150750

Statkute, Evelina, Wang, Eddie ORCID: https://orcid.org/0000-0002-2243-4964 and Stanton, Richard ORCID: https://orcid.org/0000-0002-6799-1182 2022. An optimised CRISPR/Cas9 adenovirus vector (AdZ-CRISPR) for high throughput cloning of sgRNA, using enhanced sgRNA and Cas9 variants. Human Gene Therapy 33 (17-18) , pp. 990-1001. 10.1089/hum.2021.120

Crozier, Thomas W.M., Greenwood, Edward J.D., Williamson, James C., Guo, Wenrui, Porter, Linsey M., Gabaev, Ildar, Teixeira-Silva, Ana, Grice, Guinevere L., Wickenhagen, Arthur, Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182, Wang, Eddie C. Y. ORCID: https://orcid.org/0000-0002-2243-4964, Wilson, Sam J., Matheson, Nicholas J., Nathan, James A., McCaughan, Frank and Lehner, Paul J. 2022. Quantitative proteomic analysis of SARS-CoV-2 infection of primary human airway ciliated cells and lung epithelial cells demonstrates the effectiveness of SARS-CoV-2 innate immune evasion. Wellcome Open Research 7 , 224. 10.12688/wellcomeopenres.17946.1

Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153, Sabberwal, Pragati, Williamson, James C., Greenwood, Edward J.D., Crozier, Thomas WM, Zelek, Wioleta, Seow, Jeffrey, Graham, Carl, Huettner, Isabella, Edgeworth, Jonathan D., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Morgan, Paul B. ORCID: https://orcid.org/0000-0003-4075-7676, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Eberl, Matthias ORCID: https://orcid.org/0000-0002-9390-5348, Humphreys, Ian R. ORCID: https://orcid.org/0000-0002-9512-5337, Merrick, Blair, Doores, Katie, Wilson, Sam J., Lehner, Paul J., Wang, Eddie C.Y. ORCID: https://orcid.org/0000-0002-2243-4964 and Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182 2022. SARS-CoV-2 host-shutoff impacts innate NK cell functions, but antibody-dependent NK activity is strongly activated through non-spike antibodies. eLife 11 10.7554/eLife.74489

Wang, Eddie C.Y. ORCID: https://orcid.org/0000-0002-2243-4964, Fielding, Ceri A. ORCID: https://orcid.org/0000-0002-5817-3153 and Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182 2022. Concerns over functional experiments, interpretation, and required controls. Journal of Clinical Investigation 132 (5) , e157369. 10.1172/JCI157369

Nightingale, Katie, Potts, Martin, Hunter, Leah M., Fielding, Ceri A. ORCID: https://orcid.org/0000-0002-5817-3153, Zerbe, Cassie M., Fletcher-Etherington, Alice, Nobre, Luis, Wang, Eddie C. Y. ORCID: https://orcid.org/0000-0002-2243-4964, Strang, Blair L., Houghton, Jack W., Antrobus, Robin, Suarez, Nicolas M., Nichols, Jenna, Davison, Andrew J., Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182 and Weekes, Michael P. 2022. Human cytomegalovirus protein RL1 degrades the antiviral factor SLFN11 via recruitment of the CRL4 E3 ubiquitin ligase complex. Proceedings of the National Academy of Sciences 119 (6) , e2108173119. 10.1073/pnas.2108173119

Wickenhagen, Arthur, Sugrue, Elena, Lytras, Spyros, Kuchi, Srikeerthana, Noerenberg, Marko, Turnbull, Matthew L., Loney, Colin, Herder, Vanessa, Allan, Jay, Jarmson, Innes, Cameron-Ruiz, Natalia, Varjak, Margus, Pinto, Rute M., Lee, Jeffrey Y., Iselin, Louisa, Palmalux, Natasha, Stewart, Douglas G., Swingler, Simon, Greenwood, Edward J. D., Crozier, Thomas W. M., Gu, Quan, Davies, Emma L., Clohisey, Sara, Wang, Bo, Trindade Maranhão Costa, Fabio, Freire Santana, Monique, de Lima Ferreira, Luiz Carlos, Murphy, Lee, Fawkes, Angie, Meynert, Alison, Grimes, Graeme, Da Silva Filho, Joao Luiz, Marti, Matthias, Hughes, Joseph, Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182, Wang, Eddie C. Y. ORCID: https://orcid.org/0000-0002-2243-4964, Ho, Antonia, Davis, Ilan, Jarrett, Ruth F., Castello, Alfredo, Robertson, David L., Semple, Malcolm G., Openshaw, Peter J. M., Palmarini, Massimo, Lehner, Paul J., Baillie, J. Kenneth, Rihn, Suzannah J., Wilson, Sam J., Baillie, J. Kenneth, Semple, Malcolm G., Openshaw, Peter J. M., Carson, Gail, Alex, Beatrice, Bach, Benjamin, Barclay, Wendy S., Bogaert, Debby, Chand, Meera, Cooke, Graham S., Docherty, Annemarie B., Dunning, Jake, da Silva Filipe, Ana, Fletcher, Tom, Green, Christopher A., Harrison, Ewen M., Ho, Antonia Ying Wai, Horby, Peter W., Ijaz, Samreen, Khoo, Saye, Klenerman, Paul, Law, Andrew, Lim, Wei Shen, Mentzer, Alexander J., Merson, Laura, Meynert, Alison M., Noursadeghi, Mahdad, Moore, Shona C., Palmarini, Massimo, Paxton, William A., Pollakis, Georgios, Price, Nicholas, Rambaut, Andrew, Robertson, David L., Russell, Clark D., Sancho-Shimizu, Vanessa, Scott, Janet T., de Silva, Thushan, Sigfrid, Louise, Solomon, Tom, Sriskandan, Shiranee, Stuart, David, Summers, Charlotte, Tedder, Richard S., Thomson, Emma C., Thompson, A. A. Roger, Thwaites, Ryan S., Turtle, Lance C. W., Gupta, Rishi K., Palmieri, Carlo, Swann, Olivia V., Zambon, Maria, Dumas, Marc-Emmanuel, Griffin, Julian L., Takats, Zoltan, Chechi, Kanta, Andrikopoulos, Petros, Osagie, Anthonia, Olanipekun, Michael, Liggi, Sonia, Lewis, Matthew R., dos Santos Correia, Gonçalo, Sands, Caroline J., Takis, Panteleimon, Maslen, Lynn, Hardwick, Hayley, Donohue, Chloe, Griffiths, Fiona, Oosthuyzen, Wilna, Donegan, Cara, Spencer, Rebecca G., Norman, Lisa, Pius, Riinu, Drake, Thomas M., Fairfield, Cameron J., Knight, Stephen R., Mclean, Kenneth A., Murphy, Derek, Shaw, Catherine A., Dalton, Jo, Girvan, Michelle, Saviciute, Egle, Roberts, Stephanie, Harrison, Janet, Marsh, Laura, Connor, Marie, Halpin, Sophie, Jackson, Clare, Gamble, Carrol, Plotkin, Daniel, Lee, James, Leeming, Gary, Law, Andrew, Wham, Murray, Clohisey, Sara, Hendry, Ross, Scott-Brown, James, Greenhalf, William, Shaw, Victoria, McDonald, Sarah E., Keating, Seán, Ahmed, Katie A., Armstrong, Jane A., Ashworth, Milton, Asiimwe, Innocent G., Bakshi, Siddharth, Barlow, Samantha L., Booth, Laura, Brennan, Benjamin, Bullock, Katie, Catterall, Benjamin W. A., Clark, Jordan J., Clarke, Emily A., Cole, Sarah, Cooper, Louise, Cox, Helen, Davis, Christopher, Dincarslan, Oslem, Dunn, Chris, Dyer, Philip, Elliott, Angela, Evans, Anthony, Finch, Lorna, Fisher, Lewis W. S., Foster, Terry, Garcia-Dorival, Isabel, Greenhalf, William, Gunning, Philip, Hartley, Catherine, Jensen, Rebecca L., Jones, Christopher B., Jones, Trevor R., Khandaker, Shadia, King, Katharine, Kiy, Robyn T., Koukorava, Chrysa, Lake, Annette, Lant, Suzannah, Latawiec, Diane, Lavelle-Langham, Lara, Lefteri, Daniella, Lett, Lauren, Livoti, Lucia A., Mancini, Maria, McDonald, Sarah, McEvoy, Laurence, McLauchlan, John, Metelmann, Soeren, Miah, Nahida S., Middleton, Joanna, Mitchell, Joyce, Moore, Shona C., Murphy, Ellen G., Penrice-Randal, Rebekah, Pilgrim, Jack, Prince, Tessa, Reynolds, Will, Ridley, P. Matthew, Sales, Debby, Shaw, Victoria E., Shears, Rebecca K., Small, Benjamin, Subramaniam, Krishanthi S., Szemiel, Agnieska, Taggart, Aislynn, Tanianis-Hughes, Jolanta, Thomas, Jordan, Trochu, Erwan, van Tonder, Libby, Wilcock, Eve, Zhang, J. Eunice, Flaherty, Lisa, Maziere, Nicole, Cass, Emily, Carracedo, Alejandra Doce, Carlucci, Nicola, Holmes, Anthony, Massey, Hannah, Murphy, Lee, Wrobel, Nicola, McCafferty, Sarah, Morrice, Kirstie, MacLean, Alan, Adeniji, Kayode, Agranoff, Daniel, Agwuh, Ken, Ail, Dhiraj, Aldera, Erin L., Alegria, Ana, Allen, Sam, Angus, Brian, Ashish, Abdul, Atkinson, Dougal, Bari, Shahedal, Barlow, Gavin, Barnass, Stella, Barrett, Nicholas, Bassford, Christopher, Basude, Sneha, Baxter, David, Beadsworth, Michael, Bernatoniene, Jolanta, Berridge, John, Berry, Colin, Best, Nicola, Bothma, Pieter, Chadwick, David, Brittain-Long, Robin, Bulteel, Naomi, Burden, Tom, Burtenshaw, Andrew, Caruth, Vikki, Chadwick, David, Chambler, Duncan, Chee, Nigel, Child, Jenny, Chukkambotla, Srikanth, Clark, Tom, Collini, Paul, Cosgrove, Catherine, Cupitt, Jason, Cutino-Moguel, Maria-Teresa, Dark, Paul, Dawson, Chris, Dervisevic, Samir, Donnison, Phil, Douthwaite, Sam, Drummond, Andrew, DuRand, Ingrid, Dushianthan, Ahilanadan, Dyer, Tristan, Evans, Cariad, Eziefula, Chi, Fegan, Chrisopher, Finn, Adam, Fullerton, Duncan, Garg, Sanjeev, Garg, Atul, Gkrania-Klotsas, Effrossyni, Godden, Jo, Goldsmith, Arthur, Graham, Clive, Hardy, Elaine, Hartshorn, Stuart, Harvey, Daniel, Havalda, Peter, Hawcutt, Daniel B., Hobrok, Maria, Hodgson, Luke, Hormis, Anil, Jacobs, Michael, Jain, Susan, Jennings, Paul, Kaliappan, Agilan, Kasipandian, Vidya, Kegg, Stephen, Kelsey, Michael, Kendall, Jason, Kerrison, Caroline, Kerslake, Ian, Koch, Oliver, Koduri, Gouri, Koshy, George, Laha, Shondipon, Laird, Steven, Larkin, Susan, Leiner, Tamas, Lillie, Patrick, Limb, James, Linnett, Vanessa, Little, Jeff, Lyttle, Mark, MacMahon, Michael, MacNaughton, Emily, Mankregod, Ravish, Masson, Huw, Matovu, Elijah, McCullough, Katherine, McEwen, Ruth, Meda, Manjula, Mills, Gary, Minton, Jane, Mirfenderesky, Mariyam, Mohandas, Kavya, Mok, Quen, Moon, James, Moore, Elinoor, Morgan, Patrick, Morris, Craig, Mortimore, Katherine, Moses, Samuel, Mpenge, Mbiye, Mulla, Rohinton, Murphy, Michael, Nagel, Megan, Nagarajan, Thapas, Nelson, Mark, Norris, Lillian, O?Shea, Matthew K., Otahal, Igor, Ostermann, Marlies, Pais, Mark, Palmieri, Carlo, Panchatsharam, Selva, Papakonstantinou, Danai, Paraiso, Hassan, Patel, Brij, Pattison, Natalie, Pepperell, Justin, Peters, Mark, Phull, Mandeep, Pintus, Stefania, Singh Pooni, Jagtur, Planche, Tim, Post, Frank, Price, David, Prout, Rachel, Rae, Nikolas, Reschreiter, Henrik, Reynolds, Tim, Richardson, Neil, Roberts, Mark, Roberts, Devender, Rose, Alistair, Rousseau, Guy, Ruge, Bobby, Ryan, Brendan, Saluja, Taranprit, Schmid, Matthias L., Shah, Aarti, Shanmuga, Prad, Sharma, Anil, Shawcross, Anna, Sizer, Jeremy, Shankar-Hari, Manu, Smith, Richard, Snelson, Catherine, Spittle, Nick, Staines, Nikki, Stambach, Tom, Stewart, Richard, Subudhi, Pradeep, Szakmany, Tamas, Tatham, Kate, Thomas, Jo, Thompson, Chris, Thompson, Robert, Tridente, Ascanio, Tupper-Carey, Darell, Twagira, Mary, Vallotton, Nick, Vancheeswaran, Rama, Vincent-Smith, Lisa, Visuvanathan, Shico, Vuylsteke, Alan, Waddy, Sam, Wake, Rachel, Walden, Andrew, Welters, Ingeborg, Whitehouse, Tony, Whittaker, Paul, Whittington, Ashley, Papineni, Padmasayee, Wijesinghe, Meme, Williams, Martin, Wilson, Lawrence, Cole, Sarah, Winchester, Stephen, Wiselka, Martin, Wolverson, Adam, Wootton, Daniel G., Workman, Andrew, Yates, Bryan and Young, Peter 2021. A prenylated dsRNA sensor protects against severe COVID-19. Science 374 (6567) , pp. 535-536. 10.1126/science.abj3624

Vlachava, Virginia-Maria ORCID: https://orcid.org/0000-0003-4233-7739, Murrell, Isa, Zhuang, Lihui, Aicheler, Rebecca J., Lim, Eleanor, Miners, Kelly L., Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Suárez, Nicolás M., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Davison, Andrew J., Wilkinson, Gavin W.G., Wills, Mark R., Weekes, Michael P., Wang, Eddie C.Y. ORCID: https://orcid.org/0000-0002-2243-4964 and Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182 2021. Monoclonal antibodies targeting nonstructural viral antigens can activate ADCC against human cytomegalovirus. Journal of Clinical Investigation 131 (4) , e139296. 10.1172/JCI139296

Ahmed, Raya, Miners, Kelly L., Lahoz-Beneytez, Julio, Jones, Rhiannon E., Roger, Laureline, Baboonian, Christina, Zhang, Yan, Wang, Eddie C. Y. ORCID: https://orcid.org/0000-0002-2243-4964, Hellerstein, Marc K., McCune, Joseph M., Baird, Duncan M. ORCID: https://orcid.org/0000-0001-8408-5467, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Macallan, Derek C., Asquith, Becca and Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938 2020. CD57+ Memory T Cells Proliferate In Vivo. Cell Reports 33 (11) , 108501. 10.1016/j.celrep.2020.108501

Lau, Betty, Kerr, Karen, Gu, Quan, Nightingale, Katie, Antrobus, Robin, Suárez, Nicolás M., Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182, Wang, Eddie C. Y. ORCID: https://orcid.org/0000-0002-2243-4964, Weekes, Michael P. and Davison, Andrew J. 2020. Human Cytomegalovirus long non-coding RNA1.2 suppresses extracellular release of the pro-inflammatory Cytokine IL-6 by blocking NF-κB activation. Frontiers in Cellular and Infection Microbiology 10 , 361. 10.3389/fcimb.2020.00361

Elasifer, Hana, Wang, Eddie C.Y. ORCID: https://orcid.org/0000-0002-2243-4964, Prod'homme, Virginie ORCID: https://orcid.org/0000-0002-9664-4710, Davies, James ORCID: https://orcid.org/0000-0003-3569-4500, Forbes, Simone, Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182, Patel, Mihil, Fielding, Ceri A. ORCID: https://orcid.org/0000-0002-5817-3153, Roberts, Dawn, Traherne, James A., Gruber, Nicole, Bugert, Joachim J. ORCID: https://orcid.org/0000-0002-0556-3211, Aicheler, Rebecca J. and Wilkinson, Gavin W. G. 2020. Downregulation of HLA-I by the molluscum contagiosum virus mc080 impacts NK-cell recognition and promotes CD8+ T-cell evasion. Journal of General Virology 101 , pp. 863-872. 10.1099/jgv.0.001417

Collins, Fraser L., Stone, Michael D., Turton, Jane, McCabe, Laura R., Wang, Eddie C.Y. ORCID: https://orcid.org/0000-0002-2243-4964 and Williams, Anwen S. ORCID: https://orcid.org/0000-0001-6118-020X 2019. Oestrogen-deficiency induces bone loss by modulating CD14+ monocyte and CD4+ T cell DR3 expression and serum TL1A levels. BMC Musculoskeletal Disorders 20 (1) , 326. 10.1186/s12891-019-2704-z

Nobre, Luis V., Nightingale, Katie, Ravenhill, Benjamin J., Antrobus, Robin, Soday, Lior, Nichols, Jenna, Davies, James ORCID: https://orcid.org/0000-0003-3569-4500, Seirafian, Sepehr, Wang, Eddie C.Y. ORCID: https://orcid.org/0000-0002-2243-4964, Davison, Andrew J., Wilkinson, Gavin W.G., Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182, Huttlin, Edward L. and Weekes, Michael P. 2019. Human cytomegalovirus interactome analysis identifies degradation hubs, domain associations and viral protein functions. eLife 8 , e49894. 10.7554/eLife.49894

Boelen, Lies, Debebe, Bisrat, Silveira, Marcos, Salam, Arafa, Makinde, Julia, Roberts, Chrissy h., Wang, Eddie C. Y. ORCID: https://orcid.org/0000-0002-2243-4964, Frater, John, Gilmour, Jill, Twigger, Katie, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Miners, Kelly L., Jayaraman, Jyothi, Traherne, James A., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Qi, Ying, Martin, Maureen P., Macallan, Derek C., Thio, Chloe L., Astemborski, Jacquie, Kirk, Gregory, Donfield, Sharyne M., Buchbinder, Susan, Khakoo, Salim I., Goedert, James J., Trowsdale, John, Carrington, Mary, Kollnberger, Simon and Asquith, Becca 2018. Inhibitory killer cell immunoglobulin-like receptors strengthen CD8+ T cell-mediated control of HIV-1, HCV, and HTLV-1. Science Immunology 3 (29) , eaao2892. 10.1126/sciimmunol.aao2892

Patel, Mihil, Vlachava, Virginia-Maria ORCID: https://orcid.org/0000-0003-4233-7739, Forbes, Simone K., Fielding, Ceri A. ORCID: https://orcid.org/0000-0002-5817-3153, Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182 and Wang, Edward ORCID: https://orcid.org/0000-0002-2243-4964 2018. HCMV-encoded NK modulators: Lessons from in vitro and in vivo genetic variation. Frontiers in Immunology 9 , 2214. 10.3389/fimmu.2018.02214

Nightingale, Katie, Lin, Kai-Min, Ravenhill, Benjamin J., Davies, Colin, Nobre, Luis, Fielding, Ceri A. ORCID: https://orcid.org/0000-0002-5817-3153, Ruckova, Eva, Fletcher-Etherington, Alice, Soday, Lior, Nichols, Hester ORCID: https://orcid.org/0000-0002-6814-4364, Sugrue, Daniel, Wang, Eddie C.Y. ORCID: https://orcid.org/0000-0002-2243-4964, Moreno, Pablo, Umrania, Yagnesh, Huttlin, Edward L., Antrobus, Robin, Davison, Andrew J., Wilkinson, Gavin W.G. ORCID: https://orcid.org/0000-0002-5623-0126, Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182, Tomasec, Peter and Weekes, Michael P. 2018. High-definition analysis of host protein stability during human cytomegalovirus infection reveals antiviral factors and viral evasion mechanisms. Cell Host and Microbe 24 (3) , 447-460.e11. 10.1016/j.chom.2018.07.011

Wang, Eddie C. Y. ORCID: https://orcid.org/0000-0002-2243-4964, Pjechova, Marina, Nightingale, Katie, Vlachava, Virginia-Maria ORCID: https://orcid.org/0000-0003-4233-7739, Patel, Mihil, Ruckova, Eva, Forbes, Simone K., Nobre, Luis, Antrobus, Robin, Roberts, Dawn, Fielding, Ceri A. ORCID: https://orcid.org/0000-0002-5817-3153, Seirafian, Sepehr, Davies, James ORCID: https://orcid.org/0000-0003-3569-4500, Murrell, Isa, Lau, Betty, Wilkie, Gavin S., Suarez, Nicolas M., Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182, Vojtesek, Borivoj, Davison, Andrew, Lehner, Paul J., Weekes, Michael P., Wilkinson, Gavin W. G. ORCID: https://orcid.org/0000-0002-5623-0126 and Tomasec, Peter 2018. Suppression of costimulation by human cytomegalovirus promotes evasion of cellular immune defenses. Proceedings of the National Academy of Sciences 115 (19) , pp. 4998-5003. 10.1073/pnas.1720950115

Malhotra, Nidhi, Leyva-Castillo, Juan Manuel, Jadhav, Unmesh, Barreiro, Olga, Kam, Christy, O'Neill, Nicholas K., Meylan, Francoise, Chambon, Pierre, von Andrian, Ulrich H., Siegel, Richard M., Wang, Eddie C. ORCID: https://orcid.org/0000-0002-2243-4964, Shivdasani, Ramesh and Geha, Raif S. 2018. RORα-expressing T regulatory cells restrain allergic skin inflammation. Science Immunology 3 (21) , eaao6923. 10.1126/sciimmunol.aao6923

Singh, Ravinder, Perks, William, Twohig, Jason, Kidd, Emma ORCID: https://orcid.org/0000-0001-5507-1170, Broadley, Kenneth ORCID: https://orcid.org/0000-0002-3339-2050, Farrow, S N, Williams, Anwen ORCID: https://orcid.org/0000-0001-6118-020X, Taylor, Philip ORCID: https://orcid.org/0000-0003-0163-1421 and Wang, Edward ORCID: https://orcid.org/0000-0002-2243-4964 2017. Death receptor 3 regulates distinct pathological attributes of acute versus chronic murine allergic lung inflammation. Cellular Immunology 320 , pp. 62-70. 10.1016/j.cellimm.2017.09.005

Collins, Fraser L., Williams, Jessica O. ORCID: https://orcid.org/0000-0001-6118-020X, Bloom, Anja C., Singh, Ravinder K., Jordan, Lauren, Stone, Michael D., McCabe, Laura R., Wang, Eddie C. Y. ORCID: https://orcid.org/0000-0002-2243-4964 and Williams, Anwen S. ORCID: https://orcid.org/0000-0001-6118-020X 2017. CCL3 and MMP-9 are induced by TL1A during death receptor 3 (TNFRSF25)-dependent osteoclast function and systemic bone loss. Bone 97 , pp. 94-104. 10.1016/j.bone.2017.01.002

Williams, Anwen ORCID: https://orcid.org/0000-0001-6118-020X, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Thurner, Lorenz and Liu, Chuan-ju 2016. Novel insights into TNF receptor, DR3 and progranulin pathways in arthritis and bone remodeling. Arthritis & Rheumatology 68 (12) , pp. 2845-2856. 10.1002/art.39816

Perks, William V., Singh, Ravinder K., Jones, Gareth W., Twohig, Jason P., Williams, Anwen S. ORCID: https://orcid.org/0000-0001-6118-020X, Humphreys, Ian R. ORCID: https://orcid.org/0000-0002-9512-5337, Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421, Jones, Simon A. and Wang, Eddie C. Y. ORCID: https://orcid.org/0000-0002-2243-4964 2016. Death Receptor 3 promotes chemokine directed leukocyte recruitment in acute resolving inflammation and is essential for pathological development of mesothelial fibrosis in chronic disease. American Journal of Pathology 186 (11) , pp. 2813-2823. 10.1016/j.ajpath.2016.07.021

Jia, Li-Guo, Bamias, Giorgos, Burkly, Linda C., Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Gruszka, D., Pizarro, T. T. and Cominelli, F. 2016. A novel role for TL1A/DR3 in protection against intestinal injury and infection. Journal of Immunology 197 (1) , pp. 377-386. 10.4049/​jimmunol.1502466 Item availability restricted.

Williams, Jessica, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Lang, Derek and Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X 2016. Characterisation of Death Receptor 3 dependent aortic changes during inflammatory arthritis. Pharmacology Research & Perspectives 4 (4) , e0024. 10.1002/prp2.240

Wilkinson, Gavin William Grahame ORCID: https://orcid.org/0000-0002-5623-0126, Davison, Andrew J., Tomasec, Peter, Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153, Aicheler, Rebecca, Murrell, Isa, Seirafian, Sepher, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Weekes, Michael, Lehner, Paul J., Wilkie, Gavin S. and Stanton, Richard James ORCID: https://orcid.org/0000-0002-6799-1182 2015. Human cytomegalovirus: taking the strain. Medical Microbiology and Immunology 204 (3) , pp. 273-284. 10.1007/s00430-015-0411-4

Collins, Fraser L., Williams, Jessica, Bloom, Anja C., Stone, Michael D., Choy, Ernest Ho Sing ORCID: https://orcid.org/0000-0003-4459-8609, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 and Williams, Anwen Sian 2015. Death Receptor 3 (TNFRSF25) Increases mineral apposition by osteoblasts and region specific new bone formation in the axial skeleton of male DBA/1 mice. Journal of Immunology Research 2015 , -. 10.1155/2015/901679

Wang, Eddie C. Y. ORCID: https://orcid.org/0000-0002-2243-4964, Newton, Zarabeth, Hayward, Olivia A., Clark, Stephen R. ORCID: https://orcid.org/0000-0001-5907-9671, Collins, Fraser, Perks, William V., Singh, Ravinder K., Twohig, Jason P. and Williams, Anwen S. ORCID: https://orcid.org/0000-0001-6118-020X 2014. Regulation of early cartilage destruction in inflammatory arthritis by death receptor 3. Arthritis and Rheumatology 66 (10) , pp. 2762-2772. 10.1002/art.38770

Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182, Prod'homme, Virginie ORCID: https://orcid.org/0000-0002-9664-4710, Purbhoo, Marco A., Moore, Melanie, Aicheler, Rebecca J., Heinzmann, Marcus, Bailer, Susanne M., Haas, Jürgen, Antrobus, Robin, Weekes, Michael P., Lehner, Paul J., Vojtesek, Borivoj, Miners, Kelly L., Man, Stephen ORCID: https://orcid.org/0000-0001-9103-1686, Wilkie, Gavin S., Davison, Andrew J., Wang, Eddie C. Y. ORCID: https://orcid.org/0000-0002-2243-4964, Tomasec, Peter and Wilkinson, Gavin W. G. ORCID: https://orcid.org/0000-0002-5623-0126 2014. HCMV pUL135 remodels the actin cytoskeleton to impair immune recognition of infected cells. Cell Host and Microbe 16 (2) , pp. 201-214. 10.1016/j.chom.2014.07.005

Weekes, Michael P., Tomasec, Peter, Huttlin, Edward L., Fielding, Ceri A. ORCID: https://orcid.org/0000-0002-5817-3153, Nusinow, David, Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182, Wang, Eddie C. Y. ORCID: https://orcid.org/0000-0002-2243-4964, Aicheler, Rebecca, Murrell, Isa, Wilkinson, Gavin W. G. ORCID: https://orcid.org/0000-0002-5623-0126, Lehner, Paul J. and Gygi, Steven P. 2014. Quantitative temporal viromics: an approach to investigate host-pathogen interaction. Cell 157 (6) , pp. 1460-1472. 10.1016/j.cell.2014.04.028

Fielding, Ceri A. ORCID: https://orcid.org/0000-0002-5817-3153, Aicheler, Rebecca, Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182, Wang, Eddie C. Y. ORCID: https://orcid.org/0000-0002-2243-4964, Han, Song, Seirafian, Sepehr, Davies, James, McSharry, Brian P., Weekes, Michael P., Antrobus, P. Robin, Prod'homme, Virginie ORCID: https://orcid.org/0000-0002-9664-4710, Blanchet, Fabien P., Sugrue, Daniel M., Cuff, Simone ORCID: https://orcid.org/0000-0002-0546-3579, Roberts, Dawn, Davison, Andrew J., Lehner, Paul J., Wilkinson, Gavin W. G. ORCID: https://orcid.org/0000-0002-5623-0126 and Tomasec, Peter 2014. Two novel human cytomegalovirus NK cell evasion functions target MICA for lysosomal degradation. PLoS Pathogens 10 (5) , e1004058. 10.1371/journal.ppat.1004058

Pembroke, Thomas ORCID: https://orcid.org/0000-0002-2600-2034, Christian, Adam, Jones, Emma, Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567 2013. The paradox of NKp46+ natural killer cells: drivers of severe hepatitis C virus-induced pathology but in-vivo resistance to interferon treatment. Gut n/a 10.1136/gutjnl-2013-304472

Smith, Wendell, Tomasec, Peter, Aicheler, Rebecca, Loewendorf, Andrea, Nemcovicova, Ivana, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Stanton, Richard James ORCID: https://orcid.org/0000-0002-6799-1182, Macauley, Matt, Norris, Paula, Willen, Laure, Ruckova, Eva, Nomoto, Akio, Schneider, Pascal, Hahn, Gabriele, Zajonc, Dirk M., Ware, Carl F., Wilkinson, Gavin William Grahame ORCID: https://orcid.org/0000-0002-5623-0126 and Benedict, Chris A. 2013. Human cytomegalovirus glycoprotein UL141 targets the TRAIL death receptors to thwart host innate antiviral defenses. Cell Host & Microbe 13 (3) , pp. 324-335. 10.1016/j.chom.2013.02.003

Collins, Fraser, Stone, M. D., Goodfellow, Rhian Mair, Choy, Ernest Ho Sing ORCID: https://orcid.org/0000-0003-4459-8609, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 and Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X 2012. TNF-like protein 1A/death receptor 3 pathway regulates osteoclastogenesis and is associated with erosive disease in rheumatoid arthritis. Arthritis and Rheumatism 64 (10) , S768-S768.

Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 2012. On death receptor 3 and its ligands... Immunology 137 (1) , pp. 114-116. 10.1111/j.1365-2567.2012.03606.x

Pembroke, Thomas ORCID: https://orcid.org/0000-0002-2600-2034, Rees, Ian W., Gallagher, Kathleen, Jones, Emma, Mizen, Paul Edward, Navruzov, Timur, Freedman, Andrew Robert, Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153, Humphreys, Ian R. ORCID: https://orcid.org/0000-0002-9512-5337, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567 2012. Rapid early innate control of hepatitis C virus during IFN-α treatment compromises adaptive CD4+T-cell immunity. European Journal of Immunology 42 (9) , pp. 2383-2394. 10.1002/eji.201142072

Coles, Steven, Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Burnett, Alan Kenneth, Man, Stephen Tzekwung ORCID: https://orcid.org/0000-0001-9103-1686, Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 and Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 2012. Increased CD200 expression in acute myeloid leukemia is linked with an increased frequency of FoxP3+ regulatory T cells [Letter]. Leukemia 26 (9) , pp. 2146-2148. 10.1038/leu.2012.75

Coles, Steven, Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Burnett, Alan Kenneth, Man, Stephen Tzekwung ORCID: https://orcid.org/0000-0001-9103-1686, Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 and Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 2012. Expression of CD200 on AML blasts directly suppresses memory T-cell function [Letter]. Leukemia 26 (9) , pp. 2148-2151. 10.1038/leu.2012.77

Twohig, Jason Peter, Marsden, Morgan, Cuff, Simone ORCID: https://orcid.org/0000-0002-0546-3579, Ferdinand, John R., Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004, Perks, William Victor, Al-Shamkhani, Aymen, Humphreys, Ian R. ORCID: https://orcid.org/0000-0002-9512-5337 and Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 2012. The death receptor 3/TL1A pathway is essential for efficient development of antiviral CD4+ and CD8+ T-cell immunity. The FASEB Journal 26 (8) , pp. 3575-3586. 10.1096/fj.11-200618

Pembroke, Thomas ORCID: https://orcid.org/0000-0002-2600-2034, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567 2012. PMO-174 Intrahepatic natural killer cell phenotyping and functional analysis by fine needle aspiration in chronic HCV infection. Gut 61 (S2) , A144-A145. 10.1136/gutjnl-2012-302514b.174

Collins, Fraser, Stone, M., Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 and Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X 2012. Death receptor 3 and tl1a: A regulatory pathway of bone turnover and target for osteoporosis therapy? [Abstract]. Osteoporosis International 23 , S528-S528.

Calder, Claudia Jane and Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 2012. An essential role for death receptor 3 in experimental autoimmune uveoretinitis [Letter]. Ocular Immunology and Inflammation 20 (3) , pp. 212-214. 10.3109/09273948.2012.658135

Collins, Fraser, Stone, Michael D., Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 and Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X 2012. Death receptor 3 and Tl1a: A driving force in osteoclast differentiation and potential target for rheumatoid arthritis therapy [Abstract]. Rheumatology 51 (s3) , p. 140. 10.1093/rheumatology/kes108

Al-Lamki, Rafia S., Lu, WanHua, Finlay, Sarah, Twohig, Jason Peter, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Tolkovsky, Aviva M. and Bradley, John R. 2012. DR3 signaling protects against cisplatin nephrotoxicity mediated by tumor necrosis factor. American Journal of Pathology 180 (4) , pp. 1454-1464. 10.1016/j.ajpath.2012.01.003

Prod'homme, Virginie ORCID: https://orcid.org/0000-0002-9664-4710, Tomasec, Peter, Cunningham, Charles, Lemberg, Marius K., Stanton, Richard James ORCID: https://orcid.org/0000-0002-6799-1182, McSharry, Brian, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Cuff, Simone ORCID: https://orcid.org/0000-0002-0546-3579, Martoglio, Bruno, Davison, Andrew J., Braud, Veronique M. and Wilkinson, Gavin William Grahame ORCID: https://orcid.org/0000-0002-5623-0126 2012. Human cytomegalovirus UL40 signal peptide regulates cell surface expression of the NK cell ligands HLA-E and gpUL18. The Journal of Immunology 188 (6) , pp. 2794-2804. 10.4049/jimmunol.1102068

Coles, Steven, Man, Stephen Tzekwung ORCID: https://orcid.org/0000-0001-9103-1686, Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062, Wang, Edward Chyng Yern ORCID: https://orcid.org/0000-0002-2243-4964, Burnett, Alan Kenneth, Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 and Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 2011. CD200 inhibits memory Th1 cell function in acute myeloid leukaemia (AML)[Abstract]. Immunology 135 (S1) , p. 178. 10.1111/j.1365-2567.2011.03534.x

Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Newton, Zarabeth, Collins, Fraser, Hayward, Olivia, Perks, William Victor, Singh, Ravinder, Twohig, Jason Peter and Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X 2011. Control of early cartilage destruction in inflammatory arthritis by death receptor 3 [Abstract]. Immunology 135 (s1) , p. 153. 10.1111/j.1365-2567.2011.03534.x

Stacey, Maria A., Marsden, Morgan, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Wilkinson, Gavin William Grahame ORCID: https://orcid.org/0000-0002-5623-0126 and Humphreys, Ian R. ORCID: https://orcid.org/0000-0002-9512-5337 2011. IL-10 restricts activation-induced death of NK cells during acute murine cytomegalovirus infection. The Journal of Immunology 187 (6) , pp. 2944-2952. 10.4049/jimmunol.1101021

Coles, Steven, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Man, Stephen Tzekwung ORCID: https://orcid.org/0000-0001-9103-1686, Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062, Burnett, Alan Kenneth, Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 and Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 2011. CD200 expression suppresses natural killer cell function and directly inhibits patient anti-tumor response in acute myeloid leukemia. Leukemia 25 (5) , pp. 792-799. 10.1038/leu.2011.1

Jones, Gareth Wyn, Stumhofer, Jason S., Foster, Tom, Twohig, Jason Peter, Hertzog, Paul, Topley, Nicholas, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Hunter, Christopher A., Jenkins, Brendan J., Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2011. Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation. The FASEB Journal 25 (1) , pp. 409-419. 10.1096/fj.10-166843

Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 2011. CD4+ T cells, human cytomegalovirus and end-stage renal disease. Nephrology Dialysis Transplantation 26 (5) , pp. 1467-1470. 10.1093/ndt/gfr167

Jones, Gareth Wyn, Stumhofer, J. S., Foster, T., Twohig, Jason Peter, Hertzog, P., Topley, Nicholas, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Hunter, Catherine, Jenkins, Brian J., Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 and Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 2010. Differential responsiveness of naive and activated T cells to TL1A that affect Th17 generation, maintenance and proliferation [Abstract]. Immunology 131 (s1) , p. 102. 10.1111/j.1365-2567.2010.03390.x

Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Collins, Fraser, Newton, Zarabeth, Goodfellow, Rhian Mair, Rajak, Rushda, Calder, Claudia Jean and Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 2010. Death Receptor 3 orchestrates erosive pathology in inflammatory arthritis [Poster Abstract]. Immunology 131 (s1) , p. 53. 10.1111/j.1365-2567.2010.03390.x

Coles, Steven, Man, Stephen Tzekwung ORCID: https://orcid.org/0000-0001-9103-1686, Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Burnett, Alan Kenneth, Darley, Richard Lawrence ORCID: https://orcid.org/0000-0003-0879-0724 and Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 2010. Over-expression of CD200 un acute myeloid leukemia mediates the expansion of regulatory T-lymphocytes and directly inhibits natural killer cell tumor immunity [Abstract]. Blood 116 (21) , p. 218.

McLaren, James Edward ORCID: https://orcid.org/0000-0002-7021-5934, Calder, Claudia Jane, McSharry, Brian P., Sexton, Keith John, Salter, Rebecca Claire, Singh, Nishi N., Wilkinson, Gavin William Grahame ORCID: https://orcid.org/0000-0002-5623-0126, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2010. The TNF-like protein 1A-death receptor 3 pathway promotes macrophage foam cell formation in vitro. Journal of Immunology 184 (10) , pp. 5827-5834. 10.4049/jimmunol.0903782

Twohig, Jason Peter, Roberts, Malcolm I., Gavalda, Nuria, Rees-Taylor, Emma Louise, Giralt, Albert, Adams, Deborah, Brooks, Simon Philip ORCID: https://orcid.org/0000-0001-9853-6177, Bull, Melanie Jane, Calder, Claudia Jane, Cuff, Simone ORCID: https://orcid.org/0000-0002-0546-3579, Yong, Audrey Alice, Alberch, Jordi, Davies, Alun M. ORCID: https://orcid.org/0000-0001-5841-8176, Dunnett, Stephen Bruce ORCID: https://orcid.org/0000-0003-1826-1578, Tolkovsky, Aviva M. and Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 2010. Age-dependent maintenance of motor controland corticostriatal innervation by death receptor 3. Journal of Neuroscience 30 (10) , pp. 3782-3792. 10.1523/JNEUROSCI.1928-09.2010

Taraban, V.Y., Slebioda, T. J., Willoughby, J. E., Buchan, S. L., James, S., Sheth, B., Smyth, N. R., Thomas, G. J., Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 and Al-Shamkhani, A. 2010. Sustained TL1A expression modulates effector and regulatory T-cell responses and drives intestinal goblet cell hyperplasia. Mucosal Immunology 4 (2) , pp. 186-196. 10.1038/mi.2010.70

Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Bull, Melanie, Newton, Zarabeth, Calder, Claudia Jane, Twohig, Jason Peter, Elford, Carole, Evans, Bronwen Alice James ORCID: https://orcid.org/0000-0002-3082-1008, Al-Shamkhani, A. and Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 2009. A functional role for death receptor-3 in arthritis [Abstract]. Cytokine 48 (1-2) , p. 134. 10.1016/j.cyto.2009.07.568

Twohig, Jason Peter, Pappworth, Isabel Y., Baalasubramanian, Sivasankar, Kulik, Liudmila, Bull, Melanie, Holers, V. M., Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 and Marchbank, Kevin J. 2009. Defective B cell ontogeny and humoral immune response in mice prematurely expressing human complement receptor 2 (CR2, CD21) is similar to that seen in aging wild type mice. Molecular Immunology 46 (10) , pp. 2002-2013. 10.1016/j.molimm.2009.03.007

Newton, Zarabeth, Bull, Melanie, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 and Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X 2009. The role of dr3/tl1a in cartilage depletion caused by inflammatory arthritis [Abstract]. Rhuematology 48 (s1) , I30-I30. 10.1093/rheumatology/kep713

Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Bull, Melanie, Newton, Zarabeth, Calder, Claudia Jane, Twohig, Jason Peter, Elford, Carole, Evans, Bronwen Alice James ORCID: https://orcid.org/0000-0002-3082-1008, Al-Shamkhani, A. and Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 2009. Functional role of dr3 in inflammatory arthritis: A novel target for therapy? [Abstract]. Rheumatology 48 (s1) , I8-I8. 10.1093/rheumatology/kep704

Jones, Gareth Wyn, Stumhofer, J. S., Newton, Zarabeth, Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004, Ernst, M., Topley, Nicholas, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Hunter, Catherine, Jenkins, Brian J., Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2008. TL1A/TNFSF15 promotes a STAT1-mediated suppression of IL-17-secreting T-helper cells [Abstract]. Immunology 125 (s1) , p. 62. 10.1111/j.1365-2567.2008.02974.x

Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Bull, Melanie, Newton, Zarabeth, Calder, Claudia Jane, Twohig, Jason Peter, Elford, Carole, Evans, Bronwen Alice James ORCID: https://orcid.org/0000-0002-3082-1008, Rowley, T. F., Slebioda, T. J., Taraban, V. Y., Al-Shamkhani, A. and Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 2008. The role of death receptor 3 in inflammatory arthritis [Abstract]. Immunology 125 , p. 34. 10.1111/j.1365-2567.2008.02974.x

Bull, Melanie Jane, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Newton, Zarabeth, Calder, Claudia, Twohig, Jason Peter, Elford, Carole, Evans, Bronwen Alice James ORCID: https://orcid.org/0000-0002-3082-1008, Rowley, T. F., Slebioda, T. J., Taraban, V. Y., Al-Shamkhani, A. and Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 2008. The Death Receptor 3-TNF-like protein 1A pathway drives adverse bone pathology in inflammatory arthritis. Journal of Experimental Medicine 205 (11) , pp. 2457-2464. 10.1084/jem.20072378

Meylan, Françoise, Davidson, Todd S., Kahle, Erin, Kinder, Michelle, Acharya, Krishika, Jankovic, Dragana, Bundoc, Virgilio, Hodges, Marcus, Shevach, Ethan M., Keane-Myers, Andrea, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 and Siegel, Richard M. 2008. The TNF-family receptor DR3 is essential for diverse T cell-mediated inflammatory diseases. Immunity 29 (1) , pp. 79-89. 10.1016/j.immuni.2008.04.021

Al-Lamki, Rafia S., Wang, Jun, Tolkovsky, Aviva M., Bradley, J. Andrew, Griffin, Jules L., Thiru, Sathia, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Bolton, Eleanor, Min, Wang, Moore, Paul, Pober, Jordan S. and Bradley, John R. 2008. TL1A both promotes and protects from renal inflammation and injury. Journal of the American Society of Nephrology 19 (5) , pp. 953-960. 10.1681/ASN.2007060706

McSharry, Brian P., Burgert, Hans-Gerhard, Owen, Douglas P., Stanton, Richard James ORCID: https://orcid.org/0000-0002-6799-1182, Prod'homme, Virginie, Sester, Martina, Koebernick, Katja, Groh, Veronika, Spies, Thomas, Cox, Steven, Little, Ann-Margaret, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Tomasec, Peter and Wilkinson, Gavin William Grahame ORCID: https://orcid.org/0000-0002-5623-0126 2008. Adenovirus E3/19K promotes evasion of NK cell recognition by intracellular sequestration of the NKG2D ligands major histocompatibility complex class I chain-related proteins A and B. Journal of Virology 82 (9) , pp. 4585-4594. 10.1128/JVI.02251-07

Chong, Lee Kien, Aicheler, Rebecca, Llewellyn-Lacey, Sian, Tomasec, Peter, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499 and Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 2008. Proliferation and interleukin 5 production by CD8hiCD57+ T cells. European Journal of Immunology 38 (4) , pp. 995-1000. 10.1002/eji.200737687

Jones, Gareth Wyn, Newton, Zarabeth, Nowell, Mari Ann, Jenkins, B. J., Ernst, M., Topley, Nicholas, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2008. TL1A negatively regulates development of T helper 17 cells [Abstract]. Rheumatology 47 (S2) , II20-II20. 10.1093/rheumatology/kem509

Wilkinson, Gavin William Grahame ORCID: https://orcid.org/0000-0002-5623-0126, Tomasec, Peter, Stanton, Richard James ORCID: https://orcid.org/0000-0002-6799-1182, Armstrong, Melanie, Prod'homme, Virginie ORCID: https://orcid.org/0000-0002-9664-4710, Aicheler, Rebecca, McSharry, Brian P., Rickards, Carole R., Cochrane, Daniel, Llewellyn-Lacey, Sian, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Griffin, Cora A. and Davison, Andrew J. 2008. Modulation of natural killer cells by human cytomegalovirus. Journal of Clinical Virology 41 (3) , pp. 206-212. 10.1016/j.jcv.2007.10.027

Stanton, Richard James ORCID: https://orcid.org/0000-0002-6799-1182, McSharry, Brian Patrick, Rickards, Carole Ruth, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Tomasec, Peter and Wilkinson, Gavin William Grahame ORCID: https://orcid.org/0000-0002-5623-0126 2007. Cytomegalovirus destruction of focal adhesions revealed in a high-throughput Western blot analysis of cellular protein expression. Journal of Virology 81 (15) , pp. 7860-7872. 10.1128/JVI.02247-06

Jones, Gareth Wyn, Newton, Zarabeth, Jenkins, B. J., Ernst, M., Topley, Nicholas, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2007. TL1A counteracts the IL-6 control of the STAT3-mediated development of T helper 17 cells [Abstract]. Cytokine 39 (1) , pp. 18-19.

Prod'homme, Virginie ORCID: https://orcid.org/0000-0002-9664-4710, Griffin, Cora, Aicheler, Rebecca, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, McSharry, Brian Patrick, Rickards, Carole Ruth, Stanton, Richard James ORCID: https://orcid.org/0000-0002-6799-1182, Borysiewicz, Leszek K., Lopez-Botet, Miguel, Wilkinson, Gavin William Grahame ORCID: https://orcid.org/0000-0002-5623-0126 and Tomasec, Peter 2007. The Human Cytomegalovirus MHC Class I Homolog UL18 Inhibits LIR-1+ but Activates LIR-1- NK Cells. The Journal of Immunology 178 (7) , pp. 4473-4481.

Omidvar, Nader, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Longhi, M. Paula, Smith, Richard A. G. and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2006. Expression of glycosylphosphatidylinositol-anchored CD59 on target cells enhances human NK cell-mediated cytotoxicity. Journal of immunology 176 (5) , pp. 2915-2923.

Omidvar, Nader, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Longhi, Maria P., Smith, Richard A. G. and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2006. Expression of glycosylphosphatidylinositol-anchored CD59 on target cells enhances human NK cell-mediated cytotoxicity. The Journal of Immunology 176 (5) , pp. 2915-2923. 10.4049/jimmunol.176.5.2915

Griffin, Cora, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, McSharry, Brian Patrick, Rickards, Carole Ruth, Browne, Helena, Wilkinson, Gavin William Grahame ORCID: https://orcid.org/0000-0002-5623-0126 and Tomasec, Peter 2005. Characterization of a highly glycosylated form of the human cytomegalovirus HLA class I homologue gpUL18. Journal of General Virology 86 (11) , pp. 2999-3008. 10.1099/vir.0.81126-0

Siebert, Stefan, Amos, Nick, Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Aksentijevich, Ivona, Williams, Bryan Davies and Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499 2005. Reduced tumor necrosis factor signaling in primary human fibroblasts containing a tumor necrosis factor receptor superfamily 1A mutant. Arthritis & Rheumatism 52 (4) , pp. 1287-1282. 10.1002/art.20955

Tomasec, Peter, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Davison, Andrew J., Vojtesek, Borivoj, Armstrong, Melanie, Griffin, Cora, McSharry, Brian Patrick, Morris, Rebecca J., Llewellyn-Lacey, Sian, Rickards, Carole Ruth, Nomoto, Akio, Sinzger, Christian and Wilkinson, Gavin William Grahame ORCID: https://orcid.org/0000-0002-5623-0126 2005. Downregulation of natural killer cell-activating ligand CD155 by human cytomegalovirus UL141. Nature Immunology 6 (2) , pp. 181-188. 10.1038/ni1156

Vedhara, K. and Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 2005. Assessment of the immune system in human psychoneuroimmunology. Vedhara, K. and Irwin, M. R., eds. Human Psychneuroimmunology, Oxford: Oxford University Press, pp. 53-80.

Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, McSharry, Brian Patrick, Retiere, Christelle, Tomasec, Peter, Williams, Sheila, Borysiewicz, Leszek K., Braud, Veronique M. and Wilkinson, Gavin William Grahame ORCID: https://orcid.org/0000-0002-5623-0126 2002. UL40-mediated NK evasion during productive infection with human cytomegalovirus. Proceedings of the National Academy of Sciences 99 (11) , pp. 7570-7575. 10.1073/pnas.112680099

Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Thern, Anette, Denzel, Angela, Kitson, Jeremy, Farrow, Stuart N. and Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 2001. DR3 regulates negative selection during thymocyte development. Molecular and cellular biology 21 (10) , pp. 3451-61. 10.1128/MCB.21.10.3451-3461.2001

Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Kitson, Jeremy, Thern, Anette, Williamson, Jill, Farrow, Stuart N. and Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 2001. Genomic structure, expression, and chromosome mapping of the mouse homologue for the WSL-1 (DR3, Apo3, TRAMP, LARD, TR3, TNFRSF12) gene. Immunogenetics 53 (1) , pp. 59-63. 10.1007/s002510000290

Lawson, Thomas, Man, Stephen Tzekwung ORCID: https://orcid.org/0000-0001-9103-1686, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Williams, Sheila, Amos, Nick, Gillespie, Geraldine M., Moss, Paul A. and Borysiewicz, Leszek K. 2001. Functional differences between influenza A-specific cytotoxic T lymphocyte clones expressing dominant and subdominant TCR. International Immunology 13 (11) , pp. 1383-1390. 10.1093/intimm/13.11.1383

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