Browse by All Cardiff Authors

Ahmed, Rochelle D., Vitsupakorn, Danoo, Hartwell, Kieran D., Albalawi, Karma, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Watson, Peter D. ORCID: https://orcid.org/0000-0003-0250-7852 and Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2025. Chromophore charge-state switching through copper-dependent homodimerisation of an engineered green fluorescent protein. Chemical Science 10.1039/D5SC06589E

Ahmed, Rochelle D., Jamieson, W. David ORCID: https://orcid.org/0000-0001-8260-5211, Vitsupakon, Danoo, Zitti, Athena, Pawson, Kai A., Castell, Oliver K. ORCID: https://orcid.org/0000-0002-6059-8062, Watson, Peter D. ORCID: https://orcid.org/0000-0003-0250-7852 and Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2025. Molecular dynamics guided identification of a brighter variant of superfolder Green Fluorescent Protein with increased photobleaching resistance. Communications Chemistry 8 , 174. 10.1038/s42004-025-01573-4

Gwyther, Rebecca E. A., Côté, Sébastien, Chang-Seuk, Lee, Haosen, Miao, Ramakrishnan, Krithika, Palma, Matteo and Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2024. Optimising CNT-FET biosensor design through modelling of biomolecular electrostatic gating and its application to β-lactamase detection. Nature Communications 15 , 7482. 10.1038/s41467-024-51325-6

Grigorenko, Bella L., Khrenova, Maria, Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 and Nemukhin, Alexander 2024. Histidine-assisted reduction of arylnitrenes upon photo-activation of phenyl azide chromophores in the GFP-like fluorescent proteins. Organic and Biomolecular Chemistry 22 , pp. 337-347. 10.1039/D3OB01450A

Mack, Andrew H., Menzies, Georgina ORCID: https://orcid.org/0000-0002-6600-6507, Southgate, Alex, Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995, Connor, Thomas R. ORCID: https://orcid.org/0000-0003-2394-6504 and Leitner, Thomas 2023. A proofreading mutation with an allosteric effect allows a cluster of SARS-CoV-2 viruses to rapidly evolve. Molecular Biology and Evolution 40 (10) , msad209. 10.1093/molbev/msad209

Evans, O., Singh, V., Aksakal, O., Jones, D. ORCID: https://orcid.org/0000-0001-7709-3995, Borri, P. ORCID: https://orcid.org/0000-0002-7873-3314 and Langbein, W. ORCID: https://orcid.org/0000-0001-9786-1023 2023. Low-temperature plasmonically enhanced single-molecule spectroscopy of fluorescent proteins. Presented at: The European Conference on Lasers and Electro-Optics 2023, 26-30 June 2023. 2023 Conference on Lasers and Electro-Optics Europe & European Quantum Electronics Conference (CLEO/Europe-EQEC). IEEE, 10.1109/cleo/europe-eqec57999.2023.10231465

Ramakrishnan, Krithika, Johnson, Rachel L., Winter, Samuel D., Worthy, Harley L., Thomas, Christopher, Humer, Diana C., Spadiut, Oliver, Hindson, Sarah H., Wells, Stephen, Barratt, Andrew H., Menzies, Georgina E. ORCID: https://orcid.org/0000-0002-6600-6507, Pudney, Christopher R. and Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2023. Glycosylation increases active site rigidity leading to improved enzyme stability and turnover. The FEBS Journal 290 (15) , pp. 3812-3827. 10.1111/febs.16783

Stano, Pasquale, Altamura, Emiliano, Mavelli, Fabio, Singh, Vijai and Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2023. Editorial: Fiat lux! Light-driven and light-controlled synthetic biological parts, devices, systems and processes. Frontiers in Bioengineering and Biotechnology 11 , 1201962. 10.3389/fbioe.2023.1201962

Zitti, Athena and Jones, Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2023. Expanding the genetic code: a non-natural amino acid story. Biochemist 45 (1) , pp. 2-6. 10.1042/bio_2023_102

Ahmed, Rochelle D., Auhim, Husam Sabah, Worthy, Harley L. and Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2023. Fluorescent proteins: Crystallization, structural determination, and nonnatural amino acid incorporation. Sharma, Mayank, ed. Fluorescent Proteins: Methods and Protocols, Vol. 2564. Methods in Molecular Biology, Springer, pp. 99-119. (10.1007/978-1-0716-2667-2_5)

Lee, Chang-Seuk, Gwyther, Rebecca E.A, Freeley, Mark, Jones, Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 and Palma, Matteo 2022. Fabrication and functionalisation of nanocarbon-based field-effect transistor biosensors. ChemBioChem 23 (23) , e202200282. 10.1002/cbic.202200282

Cervantes-Salguero, K., Freeley, M., Gwyther, R. E. A., Jones, D. D. ORCID: https://orcid.org/0000-0001-7709-3995, Chavez, J. L. and Palma, M. 2022. Single molecule DNA origami nanoarrays with controlled protein orientation. Biophysics Reviews 3 (3) 10.1063/5.0099294

Gwyther, Rebecca E. A., Nekrasov, Nikita P., Emilianov, Aleksei V., Nasibulin, Albert G., Ramakrishnan, Krithika, Bobrinetskiy, Ivan and Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2022. Differential bio-optoelectronic gating of semiconducting carbon nanotubes by varying the covalent attachment residue of a green fluorescent protein. Advanced Functional Materials 32 (22) , 2112374. 10.1002/adfm.202112374

Noby, Nehad, Johnson, Rachel L., Tyzack, Jonathan D., Embaby, Amira M., Saeed, Hesham, Hussein, Ahmed, Khattab, Sherine N., Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369 and Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2022. Structure-guided engineering of a family IV cold-adapted esterase expands its substrate range. International Journal of Molecular Sciences 23 (9) , 4703. 10.3390/ijms23094703

Noby, Nehad, Auhim, Husam Sabah, Winter, Samuel, Worthy, Harley L., Embaby, Amira M., Saeed, Hesham, Hussein, Ahmed, Pudney, Christopher R., Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Wells, Stephen A. and Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2021. Structure and in silico simulations of a cold-active esterase reveals its prime cold-adaptation mechanism. Open Biology 11 (12) , 210182. 10.1098/rsob.210182

Xu, Xinzhao, Bowen, Benjamin J., Gwyther, Rebecca E. A., Freeley, Mark, Grigorenko, Bella, Nemukhin, Alexander V., Eklöf-Österberg, Johnas, Moth-Poulsen, Kasper, Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 and Palma, Matteo 2021. Tuning electrostatic gating of semiconducting carbon nanotubes by controlling protein orientation in biosensing devices. Angewandte Chemie International Edition 60 (37) , pp. 20184-20189. 10.1002/anie.202104044

Johnson, Rachel L., Blaber, Hayley G., Evans, Tomas, Worthy, Harley L., Pope, Jacob R. ORCID: https://orcid.org/0000-0001-6478-5378 and Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2021. Designed artificial protein heterodimers with coupled functions constructed using bio-orthogonal chemistry. Frontiers in Chemistry 9 , 733550. 10.3389/fchem.2021.733550

Freeley, Mark, Gwyther, Rebecca E. A., Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 and Palma, Matteo 2021. DNA-directed assembly of carbon nanotube-protein hybrids. Biomolecules 11 (7) , 955. 10.3390/biom11070955

Sabah Auhim, Husam, Grigorenko, Bella L, Harris, Tessa, Aksakal, Ozan, Polyakov, Igor, Berry, Colin ORCID: https://orcid.org/0000-0002-9943-548X, dos Passos Gomes, Gabriel, Alabugin, Igor, Rizkallah, Pierre, Nemukhin, Alexander and Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2021. Stalling chromophore synthesis of the fluorescent protein Venus reveals the molecular basis of the final oxidation step. Chemical Science 12 (22) , pp. 7735-7745. 10.1039/D0SC06693A

Worthy, Harley L., Williamson, Lainey J., Auhim, Husam Sabah, Leppla, Stephen H., Sastalla, Inka, Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369 and Berry, Colin ORCID: https://orcid.org/0000-0002-9943-548X 2021. The crystal sructure of Bacillus cereus HblL1. Toxins 13 (4) , 253. 10.3390/toxins13040253

Pope, Jacob R. ORCID: https://orcid.org/0000-0001-6478-5378, Johnson, Rachel L., Jamieson, W. David ORCID: https://orcid.org/0000-0001-8260-5211, Worthy, Harley L., Kailasam, Senthilkumar, Ahmed, Rochelle D., Taban, Ismail, Auhim, Husam Sabah, Watkins, Daniel W. ORCID: https://orcid.org/0000-0003-3825-5036, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Castell, Oliver ORCID: https://orcid.org/0000-0002-6059-8062 and Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2021. Association of fluorescent protein pairs and it's significant impact on fluorescence and energy transfer. Advanced Science 8 (1) , 2003167. 10.1002/advs.202003167

Karuna, Arnica, Masia, Francesco ORCID: https://orcid.org/0000-0003-4958-410X, Chappell, Sally, Errington, Rachel ORCID: https://orcid.org/0000-0002-8016-4376, Hartley, Andrew M., Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995, Borri, Paola ORCID: https://orcid.org/0000-0002-7873-3314 and Langbein, Wolfgang ORCID: https://orcid.org/0000-0001-9786-1023 2020. Quantitative imaging of B1 cyclin expression across the cell cycle using green fluorescent protein tagging and epi-fluorescence. Cytometry Part A 97 (10) , pp. 1066-1072. 10.1002/cyto.a.24038

Bowen, Benjamin J., McGarrity, Adam R., Szeto, Jenn-Yeu A., Pudney, Christopher R. and Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2020. Switching protein metalloporphyrin binding specificity by design from iron to fluorogenic zinc. Chemical Communications 56 (31) , pp. 4308-4311. 10.1039/D0CC00596G

Thomas, Suzanne K. ORCID: https://orcid.org/0000-0003-0342-3298, Jamieson, W. David ORCID: https://orcid.org/0000-0001-8260-5211, Gwyther, Rebecca E. A., Bowen, Benjamin J., Beachey, Adam, Worthy, Harley L., MacDonald, J. Emyr ORCID: https://orcid.org/0000-0001-5504-1692, Elliott, Martin ORCID: https://orcid.org/0000-0002-9254-9898, Castell, Oliver K. ORCID: https://orcid.org/0000-0002-6059-8062 and Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2020. Site-specific protein photochemical covalent attachment to carbon nanotube side walls and its electronic impact on single molecule function. Bioconjugate Chemistry 31 (3) , pp. 584-594. 10.1021/acs.bioconjchem.9b00719

Gwyther, Rebecca E.A., Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 and Worthy, Harley L. 2019. Better together: building protein oligomers naturally and by design. Biochemical Society Transactions 47 (6) , pp. 1773-1780. 10.1042/BST20190283

Worthy, Harley L., Sabah Auhim, Husam, Jamieson, W. David ORCID: https://orcid.org/0000-0001-8260-5211, Pope, Jacob R. ORCID: https://orcid.org/0000-0001-6478-5378, Wall, Aaron, Batchlor, Robert, Johnson, Rachel L., Watkins, Daniel W. ORCID: https://orcid.org/0000-0003-3825-5036, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Castell, Oliver K. ORCID: https://orcid.org/0000-0002-6059-8062 and Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2019. Positive functional synergy of structurally integrated artificial protein dimers assembled by Click chemistry. Communications Chemistry 2 , 83. 10.1038/s42004-019-0185-5

Gulácsy, Christina E., Meade, Richard, Catici, Dragana A. M., Soeller, Christian, Pantos, G. Dan, Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995, Alibhai, Dominic, Jepson, Mark, Valev, Ventsislav K., Mason, Jody M., Williams, Robert J. and Pudney, Christopher R. 2019. Excitation-energy-dependent molecular beacon detects early stage neurotoxic Aβ aggregates in the presence of cortical neurons. ACS Chemical Neuroscience 10 (3) , pp. 1240-1250. 10.1021/acschemneuro.8b00322

Zaki, Athraa, Hartley, Andrew, Reddington, Samuel, Thomas, Suzanne ORCID: https://orcid.org/0000-0003-0342-3298, Watson, Peter ORCID: https://orcid.org/0000-0003-0250-7852, Hayes, Anthony, Moskalenko, Andy, Craciun, Monica, MacDonald, John ORCID: https://orcid.org/0000-0001-5504-1692, Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 and Elliott, Martin ORCID: https://orcid.org/0000-0002-9254-9898 2018. Defined covalent assembly of protein molecules on graphene using a genetically encoded photochemical reaction handle. RSC Advances 8 , pp. 5768-5775. 10.1039/c7ra11166e

Elliott, Martin ORCID: https://orcid.org/0000-0002-9254-9898 and Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2018. Approaches to single molecule studies of metalloprotein electron transfer using scanning probe-based techniques. Biochemical Society Transactions 46 (1) , pp. 1-9. 10.1042/BST20170229

Halliwell, Lisa M., Jathoul, Amit P. ORCID: https://orcid.org/0000-0002-6767-7775, Bate, Jack P., Worthy, Harley L., Anderson, James C., Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 and Murray, James Augustus Henry ORCID: https://orcid.org/0000-0002-2282-3839 2018. ΔFlucs: brighter photinus pyralis firefly luciferases identified by surveying consecutive single amino acid deletion mutations in a thermostable variant. Biotechnology and Bioengineering 115 (1) , pp. 50-59. 10.1002/bit.26451

Freeley, Mark, Worthy, Harley L., Ahmed, Rochelle, Bowen, Ben, Watkins, Daniel, MacDonald, J. Emyr ORCID: https://orcid.org/0000-0001-5504-1692, Zheng, Ming, Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 and Palma, Matteo 2017. Site-specific one-to-one click coupling of single proteins to individual carbon nanotubes: a single-molecule approach. Journal of the American Chemical Society 139 (49) , pp. 17834-17840. 10.1021/jacs.7b07362

Marth, Gabriella, Hartley, Andrew M., Reddington, Samuel C., Sargisson, Lauren L., Parcollet, Marlène, Dunn, Katherine E., Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 and Stulz, Eugen 2017. Precision templated bottom-up multiprotein nanoassembly through defined click chemistry linkage to DNA. ACS Nano 11 (5) , pp. 5003-5010. 10.1021/acsnano.7b01711

Hartley, Andrew M., Worthy, Harley L., Reddington, Samuel C., Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369 and Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2016. Molecular basis for functional switching of GFP by two disparate non-native post-translational modifications of a phenyl azide reaction handle. Chemical Science 7 (10) , pp. 6484-6491. 10.1039/C6SC00944A

Hartley, Andrew M., Zaki, Athraa J., McGarrity, Adam R., Robert-Ansart, Cecile, Moskalenko, Andriy V., Jones, Gareth F. ORCID: https://orcid.org/0000-0001-7709-3995, Craciun, Monica F., Russo, Saverio, Elliott, Martin ORCID: https://orcid.org/0000-0002-9254-9898, MacDonald, J. Emyr ORCID: https://orcid.org/0000-0001-5504-1692 and Jones, D. Daffydd ORCID: https://orcid.org/0000-0001-7709-3995 2015. Functional modulation and directed assembly of an enzyme through designed non-natural post-translation modification. Chemical Science 6 (7) , pp. 3712-3717. 10.1039/C4SC03900A

Arpino, James A. J., Baldwin, Amy Joy ORCID: https://orcid.org/0000-0002-2162-3771, McGarrity, Adam R., Tippmann, Eric M. and Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2015. In-frame amber stop codon replacement mutagenesis for the directed evolution of proteins containing non-canonical amino acids: identification of residues open to bio-orthogonal modification. PLoS ONE 10 (5) , e0127504. 10.1371/journal.pone.0127504

Rohamare, Sonali, Gaikwad, Sushama, Jones, Dafydd ORCID: https://orcid.org/0000-0001-7709-3995, Bhavnani, Varsha, Pal, Jayanta, Sharma, Ranu and Chatterjee, Prathit 2015. Cloning, expression and in silico studies of a serine protease from a marine actinomycete (Nocardiopsis sp. NCIM 5124). Process Biochemistry 50 (3) , pp. 378-387. 10.1016/j.procbio.2014.12.025

Reddington, Samuel C., Baldwin, Amy J. ORCID: https://orcid.org/0000-0002-2162-3771, Thompson, Rebecca, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Tippmann, Eric M. and Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2015. Directed evolution of GFP with non-natural amino acids identifies residues for augmenting and photoswitching fluorescence. Chemical Science 6 (2) , pp. 1159-1166. 10.1039/C4SC02827A

Reddington, Samuel C., Driezis, Sarunas, Hartley, Andrew M., Watson, Peter Duncan ORCID: https://orcid.org/0000-0003-0250-7852, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369 and Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2015. Genetically encoded phenyl azide photochemistry drives positive and negative functional modulation of a red fluorescent protein. RSC Advances 5 (95) , pp. 77734-77738. 10.1039/C5RA13552D

Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995, Arpino, James A. J., Baldwin, Amy Joy ORCID: https://orcid.org/0000-0002-2162-3771 and Edmundson, Matthew C. 2014. Transposon-based approaches for generating novel molecular diversity during directed evolution. Gillam, Elizabeth M. J., Copp, Janine M. and Ackerley, David, eds. Directed Evolution Library Creation: Methods and Protocols, Vol. 1179. Methods in Molecular Biology, Springer, pp. 159-172. (10.1007/978-1-4939-1053-3_11)

Arpino, James Alexander Joseph, Reddington, Samuel C., Halliwell, Lisa Marie, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369 and Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2014. Random single amino acid deletion sampling unveils structural tolerance and the benefits of helical registry shift on GFP folding and structure. Structure 22 (6) , pp. 889-898. 10.1016/j.str.2014.03.014

Arpino, James Alexander Joseph, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369 and Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2014. Structural and dynamic changes associated with beneficial engineered single-amino-acid deletion mutations in enhanced green fluorescent protein. Acta Crystallographica Section D Biological Crystallography 70 (8) , pp. 2152-2162. 10.1107/S139900471401267X

Reddington, Samuel C., Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Watson, Peter Duncan ORCID: https://orcid.org/0000-0003-0250-7852, Pearson, Rachel, Tippmann, Eric Michael and Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2013. Different photochemical events of a genetically encoded phenyl azide define and modulate GFP fluorescence. Angewandte Chemie - International Edition 52 (23) , pp. 5974-5977. 10.1002/anie.201301490

Reddington, Samuel C., Watson, Peter Duncan ORCID: https://orcid.org/0000-0003-0250-7852, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Tippmann, Eric Michael and Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2013. Genetically encoding phenyl azide chemistry: new uses and ideas for classical biochemistry. Biochemical Society Transactions 41 (5) , pp. 1177-1182. 10.1042/BST20130094

Morris, Josephine Lydia, Reddington, Samuel C., Murphy, Damien Martin ORCID: https://orcid.org/0000-0002-5941-4879, Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995, Platts, James Alexis ORCID: https://orcid.org/0000-0002-1008-6595 and Tippmann, Eric Michael 2013. Aryl azide photochemistry in defined protein environments. Organic Letters 15 (4) , pp. 728-731. 10.1021/ol3028779

Della Pia, Eduardo Antonio, Macdonald, John Emyr ORCID: https://orcid.org/0000-0001-5504-1692, Elliott, Martin ORCID: https://orcid.org/0000-0002-9254-9898 and Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2012. Direct binding of a redox protein for single-molecule electron transfer measurements. Small 8 (15) , pp. 2341-2344. 10.1002/smll.201102416

Arpino, James, Czapinska, Honorata, Piasecka, Anna, Edwards, Wayne Robert, Barker, Paul, Gajda, Michal J., Bochler, Matthias ORCID: https://orcid.org/0000-0001-7884-4463 and Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2012. Structural basis for efficient chromophore communication and energy transfer in a constructed didomain protein scaffold. Journal of the American Chemical Society 134 (33) , pp. 13632-13640. 10.1021/ja301987h

Della Pia, Eduardo Antonio, Elliott, Martin ORCID: https://orcid.org/0000-0002-9254-9898, Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 and Macdonald, J. Emyr ORCID: https://orcid.org/0000-0001-5504-1692 2012. Orientation-dependent electron transport in a single redox protein [RETRACTED]. ACS Nano 6 (1) , pp. 355-361. 10.1021/nn2036818

Reddington, Samuel C., Tippmann, Eric Michael and Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2012. Residue choice defines efficiency and influence of bioorthogonal protein modification via genetically encoded strain promoted Click chemistry. Chemical Communications 48 (67) , pp. 8419-8421. 10.1039/c2cc31887c

Arpino, James, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369 and Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2012. Crystal structure of enhanced green fluorescent protein to 1.35 Å resolution reveals alternative conformations for Glu222. PLoS ONE 7 (10) , e47132. 10.1371/journal.pone.0047132

Gamble, Michael David, Kunze, Georg, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Wilson, Keith S. and Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2012. The role of substrate specificity and metal binding in defining the activity and structure of an intracellular subtilisin. FEBS Open Bio 2 , pp. 209-215. 10.1016/j.fob.2012.07.001

Della Pia, Eduardo Antonio, Chi, Qijin, Macdonald, John Emyr ORCID: https://orcid.org/0000-0001-5504-1692, Ulstrup, Jens, Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 and Elliott, Martin ORCID: https://orcid.org/0000-0002-9254-9898 2012. Fast electron transfer through a single molecule natively structured redox protein. Nanoscale 4 (22) , pp. 7106-7113. 10.1039/c2nr32131a

Della Pia, Eduardo Antonio, Chi, Qijin, Elliott, Martin ORCID: https://orcid.org/0000-0002-9254-9898, Macdonald, John Emyr ORCID: https://orcid.org/0000-0001-5504-1692, Ulstrup, Jens and Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2012. Redox tuning of cytochrome b562 through facile metal porphyrin substitution. Chemical Communications 48 (86) , pp. 10624-10626. 10.1039/c2cc34302a

Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2011. Recombining low homology, functionally rich regions of bacterial subtilisins by combinatorial fragment exchange. PLoS ONE 6 (9) , e24319. 10.1371/journal.pone.0024319

Gamble, Michael David, Kunze, Georg, Dodson, Eleanor J., Wilson, Keith S. and Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2011. Regulation of an intracellular subtilisin protease activity by a short propeptide sequence through an original combined dual mechanism. Proceedings of the National Academy of Sciences 108 (9) , pp. 3536-3541. 10.1073/pnas.1014229108

Della Pia, Eduardo Antonio, Chi, Qijin, Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995, Macdonald, John Emyr ORCID: https://orcid.org/0000-0001-5504-1692, Ulstrup, Jens and Elliott, Martin ORCID: https://orcid.org/0000-0002-9254-9898 2011. Single-molecule mapping of long-range electron transport for a cytochrome b562 variant. Nano Letters 11 (1) , pp. 176-182. 10.1021/nl103334q

Vevodova, Jiyka, Gamble, Michael David, Kunze, Georg, Ariza, Antonio, Dodson, Eleanor, Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 and Wilson, Keith S. 2010. Crystal structure of an intracellular subtilisin reveals novel structural features unique to this subtilisin family. Structure 18 (6) , pp. 744-755. 10.1016/j.str.2010.03.008

Edwards, Wayne Robert, Williams, Abigail J., Morris, Josephine Lydia, Baldwin, Amy Joy ORCID: https://orcid.org/0000-0002-2162-3771, Allemann, Rudolf Konrad ORCID: https://orcid.org/0000-0002-1323-8830 and Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2010. Regulation of β-Lactamase activity by remote binding of Heme: functional coupling of unrelated proteins through domain insertion. Biochemistry 49 (31) , pp. 6541-6549. 10.1021/bi100793y

Stott, K. M., Yusof, A. M., Perham, R. N. and Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2009. A Surface Loop Directs Conformational Switching of a Lipoyl Domain Between a Folded and a Novel Misfolded Structure. Structure 17 (8) , pp. 1117-1127. 10.1016/j.str.2009.07.001

Baldwin, Amy Joy ORCID: https://orcid.org/0000-0002-2162-3771, Arpino, James Alexander, Edwards, W. R., Tippmann, Eric Michael and Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2009. Expanded chemical diversity sampling through whole protein evolution. Molecular Biosystems 5 (7) , pp. 764-766. 10.1039/B904031E

Baldwin, Amy Joy ORCID: https://orcid.org/0000-0002-2162-3771, Busse, K., Simm, A. M. and Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2008. Expanded molecular diversity generation during directed evolution by trinucleotide exchange (TriNEx). Nucleic Acids Research 36 (13) , e77. 10.1093/nar/gkn358

Meltzer, Michael, Hasenbein, Sonja, Hauske, Patrick, Kucz, Nicolette, Merdanovic, Melisa, Grau, Sandra, Beil, Alexandra, Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995, Krojer, Tobias, Clausen, Tim, Ehrmann, Michael ORCID: https://orcid.org/0000-0002-1927-260X and Kaiser, Markus 2008. Allosteric activation of HtrA protease DegP by stress signals during bacterial protein quality control. Angewandte Chemie - International Edition 47 (7) , pp. 1332-1334. 10.1002/anie.200703273

Edwards, W. R., Busse, K., Allemann, Rudolf Konrad ORCID: https://orcid.org/0000-0002-1323-8830 and Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2008. Linking the functions of unrelated proteins using a novel directed evolution domain insertion method. Nucleic Acids Research 36 (13) 10.1093/nar/gkn363

Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 and Perham, R. N. 2008. The role of loop and β-turn residues as structural and functional determinants for the lipoyl domain from the Escherichia coli 2-oxoglutarate dehydrogenase complex. Biochemical Journal 409 , pp. 357-366. 10.1042/BJ20071119

Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 and Perham, Richard N. 2007. The role of loop and β-turn residues as structural and functional determinants for the lipoyl domain from the Escherichia coli 2-oxoglutarate dehydrogenase complex. Biochemical Journal 409 , pp. 357-366. 10.1042/BJ20071119

Simm, Alan M., Baldwin, Amy Joy ORCID: https://orcid.org/0000-0002-2162-3771, Busse, Kathy and Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2007. Investigating protein structural plasticity by surveying the consequence of an amino acid deletion from TEM-1 β-lactamase. FEBS Letters 581 (21) , pp. 3904-3908. 10.1016/j.febslet.2007.07.018

Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 and Barker, P.D. 2005. Controlling self-assembly by linking protein folding, DNA binding and the redox chemistry of heme. Angewandte Chemie International Edition , pp. 6337-6341. 10.1002/anie.200463035

Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 2005. Triplet nucleotide removal at random positions in a target gene: the tolerance of TEM-1 β-lactamase to an amino acid deletion. Nucleic Acids Research 33 (9) 10.1093/nar/gni077

Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995 and Barker, Paul D. 2004. Design and characterisation of an artificial DNA-binding cytochrome. ChemBioChem 5 (7) , pp. 964-971. 10.1002/cbic.200300569

Perham, Richard N., Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995, Chauhan, Hitesh J. and Howard, Mark J. 2002. Substrate channelling in 2-oxo acid dehydrogenase multienzyme complexes. Biochemical Society Transactions 30 (2) , 47–51. 10.1042/0300-5127:0300047

Jones, Darran Dafydd ORCID: https://orcid.org/0000-0001-7709-3995, Perham, R.N., Reche, P.A. and Stott, K.M. 2001. Recognition of the lipoyl domain is the ultimate determinant of substrate channelling in the pyruvate dehydrogenase multienzyme complex. Journal of Molecular Biology , pp. 49-60. 10.1006/jmbi.2000.4257

Jones, D. Dafydd ORCID: https://orcid.org/0000-0001-7709-3995, Stott, Katherine M., Howard, Mark J. and Perham, Richard N. 2000. Restricted motion of the lipoyl-lysine swinging arm in the pyruvate dehydrogenase complex of Escherichia coli†,‡. Biochemistry 39 (29) , 8448–8459. 10.1021/bi992978i

Jones, D.Dafydd ORCID: https://orcid.org/0000-0001-7709-3995, Horne, H.James, Reche, Pedro A and Perham, Richard N 2000. Structural determinants of post-translational modification and catalytic specificity for the lipoyl domains of the pyruvate dehydrogenase multienzyme complex of Escherichia coli. Journal of Molecular Biology 295 (2) , pp. 289-306. 10.1006/jmbi.1999.3335