Schepelmann, Martin ORCID: https://orcid.org/0000-0002-7017-5426, Ranieri, Marianna, Lopez-Fernandez, Irene, Webberley, Thomas S., Brennan, Sarah C. ORCID: https://orcid.org/0000-0002-8719-4367, Yarova, Polina L., Graca, Joao, Hanif, Umar-Khetaab, Müller, Christian, Manhardt, Teresa, Salzmann, Martina, Quasnichka, Helen, Price, Sally A., Ward, Donald T., Gilbert, Thierry, Matchkov, Vladimir V., Fenton, Robert A., Herberger, Amanda, Hwong, Jenna, Santa Maria, Christian, Tu, Chia-Ling, Kallay, Enikö, Valenti, Giovanna, Chang, Wenhan and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163
2022.
Impaired mineral ion metabolism in a mouse model of targeted calcium-sensing receptor (CaSR) deletion from vascular smooth muscle cells.
Journal of the American Society of Nephrology
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, pp. 1323-1340.
10.1681/ASN.2021040585
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Pasqualetto, Gaia, Pileggi, Elisa, Schepelmann, Martin ORCID: https://orcid.org/0000-0002-7017-5426, Varricchio, Carmine ORCID: https://orcid.org/0000-0002-1673-4768, Rozanowska, Malgorzata ORCID: https://orcid.org/0000-0003-2913-8954, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 and Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868
2021.
Ligand-based rational design, synthesis and evaluation of novel potential chemical chaperones for opsin.
European Journal of Medicinal Chemistry
226
, 113841.
10.1016/j.ejmech.2021.113841
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Yarova, Polina L., Huang, Ping, Schepelmann, Martin W. ORCID: https://orcid.org/0000-0002-7017-5426, Bruce, Richard, Ecker, Rupert, Nica, Robert, Telezhkin, Vsevolod S. ORCID: https://orcid.org/0000-0002-5054-8774, Traini, Daniela, Gomes dos Reis, Larissa, Kidd, Emma J. ORCID: https://orcid.org/0000-0001-5507-1170, Ford, William R. ORCID: https://orcid.org/0000-0002-8792-6169, Broadley, Kenneth J., Kariuki, Benson M., Corrigan, Christopher J., Ward, Jeremy P. T., Kemp, Paul J. and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163
2021.
Characterisation of negative allosteric modulators of the calcium-sensing receptor, CaSR, for repurposing as a treatment for asthma.
Journal of Pharmacology and Experimental Therapeutics
376
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, pp. 51-63.
10.1124/jpet.120.000281
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Pasqualetto, Gaia, Schepelmann, Martin ORCID: https://orcid.org/0000-0002-7017-5426, Varricchio, Carmine ORCID: https://orcid.org/0000-0002-1673-4768, Pileggi, Elisa, Khogali, Caroline, Morgan, Siân R., Boostrom, Ian, Rozanowska, Malgorzata ORCID: https://orcid.org/0000-0003-2913-8954, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Ferla, Salvatore ORCID: https://orcid.org/0000-0002-5918-9237 and Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868
2020.
Computational studies towards the identification of novel rhodopsin-binding compounds as chemical chaperones for misfolded opsins.
Molecules
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, 4904.
10.3390/molecules25214904
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Scott Roberts, Mary, Gafni, Rachel I, Brillante, Beth, Guthrie, Lori C, Streit, Jamie, Gash, David, Gelb, Jeff, Krusinska, Eva, Brennan, Sarah C ORCID: https://orcid.org/0000-0002-8719-4367, Schepelmann, Martin ORCID: https://orcid.org/0000-0002-7017-5426, Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163, Ezuan Bin Khayat, Mohd, Ward, Donald T, Nemeth, Edward F, Rosskamp, Ralf and Collins, Michael T
2019.
Treatment of autosomal dominant hypocalcemia Type 1 with the calcilytic NPSP795 (SHP635).
Journal of Bone and Mineral Research
34
(9)
, pp. 1609-1618.
10.1002/jbmr.3747
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Pasqualetto, Gaia, Pileggi, Elisa, Schepelmann, Martin ORCID: https://orcid.org/0000-0002-7017-5426, Heard, Charles ORCID: https://orcid.org/0000-0001-9703-9777, Young, Mark Thomas ORCID: https://orcid.org/0000-0002-9615-9002, Rozanowska, Malgorzata B. ORCID: https://orcid.org/0000-0003-2913-8954, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 and Bassetto, Marcella
2019.
Novel small-molecule chaperones to overcome opsin misfolding, mistrafficking and aggregation in retinal blinding diseases.
Presented at: 2019 ARVO Annual Meeting,
Vancouver, Canada,
28 April - 02 May 2019.
Investigative ophthalmology & visual science.
, vol.60
(9)
ARVO,
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Graca, Joao, Schepelmann, Martin ORCID: https://orcid.org/0000-0002-7017-5426, Brennan, Sarah C., Reens, Jaimini, Chang, Wenhan, Yan, Paul, Toka, Hakan, Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Price, Sally A.
2016.
Comparative expression of the extracellular calcium sensing receptor in rat, mouse and human kidney.
American Journal of Physiology-Renal Physiology
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, F518-F533.
10.1152/ajprenal.00208.2015
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Schepelmann, M. ORCID: https://orcid.org/0000-0002-7017-5426, Yarova, P. L., Lopez-Fernandez, I., Davies, T. S., Brennan, S. C. ORCID: https://orcid.org/0000-0002-8719-4367, Edwards, P. J., Aggarwal, A., Graca, J., Rietdorf, K., Matchkov, V., Fenton, R. A., Chang, W., Krssak, M., Stewart, A., Broadley, K. J. ORCID: https://orcid.org/0000-0002-3339-2050, Ward, D. T., Price, S. A., Edwards, D. H., Kemp, P. J. ORCID: https://orcid.org/0000-0003-2773-973X and Riccardi, D. ORCID: https://orcid.org/0000-0002-7322-3163
2016.
The vascular Ca2+-sensing receptor regulates blood vessel tone and blood pressure.
American Journal of Physiology - Cell Physiology
310
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, C193-C204.
10.1152/ajpcell.00248.2015
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Lopez-Fernandez, Irene, Schepelmann, Martin ORCID: https://orcid.org/0000-0002-7017-5426, Brennan, Sarah C. ORCID: https://orcid.org/0000-0002-8719-4367, Yarova, Polina L. and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163
2015.
The calcium-sensing receptor: one of a kind.
Experimental Physiology
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, pp. 1392-1399.
10.1113/EP085137
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Brennan, Sarah C. ORCID: https://orcid.org/0000-0002-8719-4367, Davies, Thomas S., Schepelmann, Martin ORCID: https://orcid.org/0000-0002-7017-5426 and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163
2014.
Emerging roles of the extracellular calcium-sensing receptor in nutrient sensing: control of taste modulation and intestinal hormone secretion.
British Journal of Nutrition
111
(S1)
, S16-S22.
10.1017/S0007114513002250
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Schepelmann, Martin ORCID: https://orcid.org/0000-0002-7017-5426
2014.
Determining the role of the calcium sensing receptor in vascular smooth muscle cells via targeted gene deletion.
PhD Thesis,
Cardiff University.
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