Browse by All Cardiff Authors

Griffiths, Lauren, Hawkins, Kristen, Yutuc, Eylan, Angelini, Roberto, Fosuah, Racheal, Pacciarini, Manuela, Dickson, Alison, Robertson, Neil ORCID: https://orcid.org/0000-0002-5409-4909, Childs, Laura, Loveless, Samantha ORCID: https://orcid.org/0000-0002-5124-4115, Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634, Griffiths, William, Wang, Yuqin and Howell, Owain 2025. Sterol imbalances and cholesterol-24-hydroxylase dysregulation is linked to the underlying progression of multiple sclerosis. Brain Pathology 35 (5) , e70001. 10.1111/bpa.70001

Dobson, Ruth, Arun, Tarunya, Varley, James, Chataway, Jeremy, Brownlee, Wallace, Gallagher, Paul, Giovannoni, Gavin, Gray, Orla, Ingram, Gillian, MacDougall, Niall, Muraro, Paolo, Murray, Katy, Paling, David, Petheram, Kate, Rashid, Waqar, Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634, Trip, S. Anand and Coles, Alasdair 2025. Approach to JCV testing with natalizumab biosimilar: a UK consensus statement. Multiple Sclerosis and Related Disorders 100 , 106541. 10.1016/j.msard.2025.106541

Tallantyre, Emma C. ORCID: https://orcid.org/0000-0002-3760-6634, Jacob, Emily, Davies, Laura, Loveless, Samantha ORCID: https://orcid.org/0000-0002-5124-4115, Carne, Emily, Bramhall, Kath, Schulze, Janika, Moat, Stuart J. and Jolles, Stephen 2025. Home-sampling of B cells using quantitative dried blood spots to enable tailored therapeutic re-dosing of anti-CD20 therapies. Multiple Sclerosis Journal 31 (8) , pp. 1007-1010. 10.1177/13524585251330962

Allen, Christopher Martin, Clarke, Margareta A., Pai, Hari V., Cauchi, Marija, Hawken, Jonathan, Htet, Zin M., Allen-Philbey, Kimberley, Mohamed, Bader, Fitzsimmons, Deborah, Das Nair, Roshan, Morgan, Paul, Partlett, Christopher, Dineen, Rob A., Schmierer, Klaus, Tallantyre, Emma Clare ORCID: https://orcid.org/0000-0002-3760-6634 and Evangelou, Nikos 2025. Comparison of the diagnostic performance of the central vein sign and CSF oligoclonal bands supporting the diagnosis of multiple sclerosis. Neurology Open Access 1 (2) , e000021. 10.1212/wn9.0000000000000017

Wood, C., Owen, S., Anand, B., Wardle, M., Hamandi, K., Kreft, K. L., Robertson, N. P. ORCID: https://orcid.org/0000-0002-5409-4909 and Tallantyre, E. ORCID: https://orcid.org/0000-0002-3760-6634 2025. Multiple sclerosis and seizures: clinical, diagnostic and therapeutic correlations. Brain and Behavior 15 (5) , e70511. 10.1002/brb3.70511

Androdias, Géraldine, Lünemann, Jan D, Maillart, Elisabeth, Amato, Maria Pia, Audoin, Bertrand, Bruijstens, Arlette L, Bsteh, Gabriel, Butzkueven, Helmut, Ciccarelli, Olga, Cobo-Calvo, Alvaro, Derfuss, Tobias, Di Pauli, Franziska, Edan, Gilles, Enzinger, Christian, Geraldes, Ruth, Granziera, Cristina, Hacohen, Yael, Hartung, Hans-Peter, Hynes, Sinéad, Inglese, Matilde, Kappos, Ludwig, Kuusisto, Hanna, Langer-Gould, Annette, Magyari, Melinda, Marignier, Romain, Montalban, Xavier, Mycko, Marcin P, Nourbakhsh, Bardia, Oh, Jiwon, Oreja-Guevara, Celia, Piehl, Fredrik, Prosperini, Luca, Sastre-Garriga, Jaume, Sellebjerg, Finn, Selmaj, Krzysztof, Siva, Aksel, Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634, van Pesch, Vincent, Vukusic, Sandra, Weinstock-Guttman, Bianca, Zipp, Frauke, Tintoré, Mar, Iacobaeus, Ellen and Stankoff, Bruno 2025. De-escalating and discontinuing disease-modifying therapies in multiple sclerosis. Brain 148 (5) , pp. 1459-1478. 10.1093/brain/awae409

Davies, Laura, Shehadeh, Rasheed, Watkins, W. John ORCID: https://orcid.org/0000-0003-3262-6588, Jolles, Stephen, Robertson, Neil P. ORCID: https://orcid.org/0000-0002-5409-4909 and Tallantyre, Emma C. ORCID: https://orcid.org/0000-0002-3760-6634 2025. Real-world observational study of infections in people treated with ocrelizumab for multiple sclerosis. Journal of Neurology 272 , 415. 10.1007/s00415-025-13133-w

Arun, Tarunya, Petheram, Kate, Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634, Ford, Helen, Chataway, Jeremy, Dougall, Niall Mac, Doshi-Singh, Anisha, Englezou, Christina, Farrell, Rachel, Hughes, Stella, Donnell, Gavin Mc, Murray, Katy, Rees, Richard, Robertson, Neil, Schmierer, Klaus and Dobson, Ruth 2024. Assessing the landscape and charting paths: UK neurology trainees' opinions on neuroinflammation subspecialty. Multiple Sclerosis and Related Disorders 92 , 106144. 10.1016/j.msard.2024.106144 Item availability restricted.

Coerver, E., Schoof, L., Hogenboom, L., Wessels, M., van Ruyven, P., van Samkar, A., Mostert, J., van Kempen, Z., van Oosten, B.W., Wokke, B.H., Tallantyre, E. ORCID: https://orcid.org/0000-0002-3760-6634, Myhr, KM., Torkildsen, O., Killestein, J., Smets, I. and Strijbis, E. 2024. The recurrence of disease activity after ocrelizumab discontinuation in multiple sclerosis. Multiple Sclerosis and Related Disorders 91 , 105900. 10.1016/j.msard.2024.105900

Nicholas, Richard, Tallantyre, Emma Clare ORCID: https://orcid.org/0000-0002-3760-6634, Witts, James, Marrie, Ruth Ann, Craig, Elaine M., Knowles, Sarah, Pearson, Owen Rhys, Harding, Katherine, Kreft, Karim, Hawken, J., Ingram, Gillian, Morgan, Bethan, Middleton, Rodden M., Robertson, Neil ORCID: https://orcid.org/0000-0002-5409-4909 and Research Group, UKMS Register 2024. Algorithmic approach to finding people with multiple sclerosis using routine healthcare data in Wales. Journal of Neurology, Neurosurgery & Psychiatry 96 (11) , pp. 1032-1035. 10.1136/jnnp-2024-333532

Gelissen, Liza M.Y., Loveless, Sam ORCID: https://orcid.org/0000-0002-5124-4115, Toorop, Alyssa A., Howlett, Jayne, Loeff, Floris C., Rispens, Theo, Killestein, Joep, Tallantyre, Emma C. ORCID: https://orcid.org/0000-0002-3760-6634 and van Kempen, Zoé L.E. 2024. Subcutaneous administration of natalizumab can lead to lower drug concentrations compared to intravenous administration. Multiple Sclerosis and Related Disorders 90 , 105796. 10.1016/j.msard.2024.105796

Roos, Izanne, Sharmin, Sifat, Malpas, Charles, Ozakbas, Serkan, Lechner-Scott, Jeannette, Hodgkinson, Suzanne, Alroughani, Raed, Eichau Madueño, Sara, Boz, Cavit, van der Walt, Anneke, Butzkueven, Helmut, Buzzard, Katherine, Skibina, Olga, Foschi, Matteo, Grand?Maison, Francois, John, Nevin, Grammond, Pierre, Terzi, Murat, Prévost, Julie, Barnett, Michael, Laureys, Guy, Van Hijfte, Liesbeth, Luis Sanchez-Menoyo, Jose, Blanco, Yolanda, Oh, Jiwon, McCombe, Pamela, Ramo Tello, Cristina, Soysal, Aysun, Prat, Alexandre, Duquette, Pierre, Yamout, Bassem I., Khoury, Samia, van Pesch, Vincent, Macdonell, Richard, José Sá, Maria, Slee, Mark, Kuhle, Jens, Maimone, Davide, Spitaleri, Daniele L.A., Willekens, Barbara, Asmi, Abdallah Al, Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634, Robertson, Neil P. ORCID: https://orcid.org/0000-0002-5409-4909, Coles, Alasdair, L Brown, J. William and Kalincik, Tomas 2024. Effectiveness of cladribine compared to fingolimod, natalizumab, ocrelizumab and alemtuzumab in relapsing-remitting multiple sclerosis. Multiple Sclerosis Journal 30 (9) , pp. 1163-1175. 10.1177/13524585241267211

Tallantyre, Emma C. ORCID: https://orcid.org/0000-0002-3760-6634, Dobson, Ruth, Froud, Joseph L. J., St John, Frederika A., Anderson, Valerie M., Arun, Tarunya, Buckley, Lauren, Evangelou, Nikos, Ford, Helen L., Galea, Ian, George, Sumi, Gray, Orla M., Hibbert, Aimee M., Hu, Mo, Hughes, Stella E., Ingram, Gillian, Kalra, Seema, Lim, Chia-Hui, Mathews, Joela T. M., McDonnell, Gavin V., Mescall, Naomi, Norris, Sam, Ramsay, Stephen J., Rice, Claire M., Russell, Melanie J., Shawe-Taylor, Marianne J., Williams, Thomas E., Harding, Katherine E. and Robertson, Neil P. ORCID: https://orcid.org/0000-0002-5409-4909 2024. Real world persistence of multiple sclerosis disease modifying therapies. European Journal of Neurology 31 (7) , e16289. 10.1111/ene.16289

De Dios perez, Blanca, Pritchard, Charlotte, Powers, Katie, das Nair, Roshan, Evangelou, Nikos, Ford, Helen, Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634, Dobson, Ruth and Radford, Kathryn 2024. The Impact of Covid-19 on the employment of people with multiple sclerosis: A multi-methods study. International Journal of MS Care 26 (Q3) , pp. 174-186. 10.7224/1537-2073.2023-049

Uzochukwu, Emeka C., Harding, Katherine E., Hrastelj, James ORCID: https://orcid.org/0000-0002-7991-5259, Kreft, Karim L., Holmans, Peter ORCID: https://orcid.org/0000-0003-0870-9412, Robertson, Neil P. ORCID: https://orcid.org/0000-0002-5409-4909, Tallantyre, Emma C. ORCID: https://orcid.org/0000-0002-3760-6634 and Lawton, Michael 2024. Modelling disease progression of Multiple Sclerosis in a South Wales cohort. Neuroepidemiology 58 (3) , pp. 218-226. 10.1159/000536427

Nasir, Moneed, Hone, Luke, Palace, jacqueline, Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634, Kelly, Patricia, Leite, Maria Isabel, Robertson, Neil ORCID: https://orcid.org/0000-0002-5409-4909, Bestwick, Jonathan, Huda, Saif and Dobson, Ruth 2024. Impact of rituximab treatment regime on time to relapse in aquaporin-4 antibody positive neuromyelitis optica spectrum disorder. Multiple Sclerosis and Related Disorders 85 , 105528. 10.1016/j.msard.2024.105528

Kreft, Karim L., Uzochukwu, Emeka, Loveless, Sam ORCID: https://orcid.org/0000-0002-5124-4115, Willis, Mark ORCID: https://orcid.org/0000-0003-3024-6063, Wynford-Thomas, Ray, Harding, Katharine E., Holmans, Peter ORCID: https://orcid.org/0000-0003-0870-9412, Lawton, Michael, Tallantyre, Emma C. ORCID: https://orcid.org/0000-0002-3760-6634 and Robertson, Neil P. ORCID: https://orcid.org/0000-0002-5409-4909 2024. Relevance of multiple sclerosis severity genotype in predicting disease course: A real-world cohort. Annals of Neurology 95 (3) , pp. 459-470. 10.1002/ana.26831

Kodosaki, Eleftheria, Watkins, W. John ORCID: https://orcid.org/0000-0003-3262-6588, Loveless, Sam ORCID: https://orcid.org/0000-0002-5124-4115, Kreft, Karim L., Richards, Aidan, Anderson, Valerie, Hurler, Lisa, Robertson, Neil P. ORCID: https://orcid.org/0000-0002-5409-4909, Zelek, Wioleta M. and Tallantyre, Emma C. ORCID: https://orcid.org/0000-0002-3760-6634 2024. Combination protein biomarkers predict multiple sclerosis diagnosis and outcomes. Journal of Neuroinflammation 21 (1) , 52. 10.1186/s12974-024-03036-4

Papathanasiou, Athanasios, Hibbert, Aimee, Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634, Harding, Katharine, Panneer Selvam, Adithya, Morgan, Matthew, Quainton, Charlotte, Talaei, Maryam, Arun, Tarunya, Ingram, Gillian, Law, Graham R. and Evangelou, Nikos 2023. Real world annualized relapse rates from contemporary multiple sclerosis clinics in the UK: A retrospective multicentre cohort study. Neurological Sciences 44 , pp. 3629-3635. 10.1007/s10072-023-06838-1

Zaloum, Safiya, Wood, Callum, Tank, Pooja, Upcott, Matthew, Vickaryous, Nicola, Anderson, Valerie, Baker, David, Randy, Chance, Evangelou, Nikos, George, Katila, Giovannoni, Gavin, Harding, Katherine, Hibbert, Aimee, Ingram, Gillian, Jolles, Stephen, Kang, Angray, Loveless, Samantha ORCID: https://orcid.org/0000-0002-5124-4115, Moat, Stuart J., Richards, Aidan, Robertson, Neil P. ORCID: https://orcid.org/0000-0002-5409-4909, Rios, Francesca, Schmierer, Klaus, Willis, Mark, Dobson, Ruth and Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634 2023. Risk of COVID-19 in people with multiple sclerosis who are seronegative following vaccination. Multiple Sclerosis Journal 29 (8) , pp. 979-989. 10.1177/13524585231185247

Htet, Z. M. and Tallantyre, E. ORCID: https://orcid.org/0000-0002-3760-6634 2023. Optic neuritis and MOGAD. Journal of Neurology 270 (6) , 3278–3279. 10.1007/s00415-023-11738-7

Jacobs, Benjamin M., Schalk, Luisa, Dunne, Angie, Scalfari, Antonio, Nandoskar, Ashwini, Gran, Bruno, Mein, Charles A., Sellars, Charlotte, Spilker, Cord, Rog, David, Visentin, Elisa, Bezzina, Elizabeth Lindsey, Uzochukwu, Emeka, Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634, Wozniak, Eva, Sacre, Eve, Hassan-Smith, Ghaniah, Ford, Helen L., Harris, Jade, Bradley, Joan, Breedon, Joshua, Brooke, Judith, Kreft, Karim L., George, Katila, Papachatzaki, Maria, O'Malley, Martin, Peter, Michelle, Mattoscio, Miriam, Rhule, Neisha, Evanelou, Nikos, Vinod, Nimisha, Quinn, Outi, Shamji, Ramya, Kaimal, Rashmi, Boulton, Rebecca, Tanveer, Riffat, Middleton, Rod, Murray, Roxanne, Bellfield, Ruth, Hoque, Sadid, Raj, Sonia, Gumus, Stephanie, Mitchell, Stephanie, Sawcer, Stephen, Arun, Tarunya, Pogreban, Tatiana, Brown, Terri-Louise, Begum, Thamanna, Antoine, Veronica, Rashid, Waqar, Noyce, Alastair J., Silber, Eli, Morris, Huw, Giovannoni, Gavin and Dobson, Ruth 2023. The ADAMS project - a genetic Association study in individuals from Diverse Ancestral backgrounds with Multiple Sclerosis based in the United Kingdom. BMJ Open 13 , e071656. 10.1136/bmjopen-2023-071656

Morgan, Annalisa, Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634 and Ontaneda, Daniel 2023. The benefits and risks of escalation versus early highly effective treatment in patients with multiple sclerosis. Expert Review of Neurotherapeutics 23 (5) , pp. 433-444. 10.1080/14737175.2023.2208347

Harding, Katharine Elizabeth, Ingram, Gillian, Tallantyre, Emma Clare ORCID: https://orcid.org/0000-0002-3760-6634, Joseph, Fady, Wardle, Mark, Pickersgill, Trevor P., Willis, Mark D. ORCID: https://orcid.org/0000-0003-3024-6063, Tomassini, Valentina ORCID: https://orcid.org/0000-0002-7368-6280, Pearson, Owen Rhys and Robertson, Neil P. ORCID: https://orcid.org/0000-0002-5409-4909 2023. Contemporary study of multiple sclerosis disability in South East Wales. Journal of Neurology, Neurosurgery and Psychiatry 94 (4) , pp. 272-279. 10.1136/jnnp-2022-330013

Garjani, Afagh, Jun-Yu Liu, Brandon, Allen, Christopher Martin, Gunzler, Douglas David, Gerry, Stephen William, Planchon, Sarah Marie, das Nair, Roshan, Chataway, Jeremy, Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634, Ontaneda, Daniel and Evangelou, Nikos 2023. Decentralised clinical trials in multiple sclerosis research. Multiple Sclerosis Journal 29 (3) , pp. 317-325. 10.1177/13524585221100401

Beesley, Rebecca, Cauchi, Maria, Davies, L., Upcott, M., Norton, E., Loveless, Sam ORCID: https://orcid.org/0000-0002-5124-4115, Anderson, V., Wynford-Thomas, Rachael, Pickersgill, T. P., Uzochukwu, E., Wardle, M., Robertson, Neil ORCID: https://orcid.org/0000-0002-5409-4909, Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634 and Willis, Mark ORCID: https://orcid.org/0000-0003-3024-6063 2022. Multiple sclerosis and COVID-19: Assessing risk perception, patient behaviours and access to disease-modifying therapies. Multiple Sclerosis and Related Disorders 68 , 104121. 10.1016/j.msard.2022.104121

Cauchi, Marija, Willis, Mark ORCID: https://orcid.org/0000-0003-3024-6063, Andrews, Angela, Backx, Matthijs, Brownlee, Wallace, Ford, Helen, Gran, Bruno, Jolles, Stephen, Price, Sian, Rashid, Waqar, Schmeirer, Klaus and Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634 2022. Multiple Sclerosis and the risk of infection: Association of British Neurologists consensus guideline. Practical Neurology 22 (5) , pp. 344-357. 10.1136/practneurol-2022-003370

Tallantyre, Emma C. ORCID: https://orcid.org/0000-0002-3760-6634, Scurr, Martin J. ORCID: https://orcid.org/0000-0002-4120-0688, Vickaryous, Nicola, Richards, Aidan, Anderson, Valerie, Baker, David, Chance, Randy, Evangelou, Nikos, George, Katila, Giovannoni, Gavin, Harding, Katharine E., Hibbert, Aimee, Ingram, Gillian, Jolles, Stephen, Jones, Meleri, Kang, Angray S., Loveless, Samantha, Moat, Stuart J., Robertson, Neil P. ORCID: https://orcid.org/0000-0002-5409-4909, Rios, Francesca, Schmierer, Klaus, Willis, Mark ORCID: https://orcid.org/0000-0003-3024-6063, Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567 and Dobson, Ruth 2022. Response to COVID-19 booster vaccinations in seronegative people with multiple sclerosis. Multiple Sclerosis and Related Disorders 64 , 103937. 10.1016/j.msard.2022.103937

Tallantyre, Emma C. ORCID: https://orcid.org/0000-0002-3760-6634 2022. Long-term treatment with anti-CD20 monoclonal antibodies is untenable because of risk ? No. Multiple Sclerosis Journal 28 (8) , pp. 1175-1177. 10.1177/13524585221091404

Garjani, Afagh, Hunter, Rachael, Law, Graham R., Middleton, Rodden M., Tuite-Dalton, Katherine A., Dobson, Ruth, Ford, David V., Hughes, Stella, Pearson, Owen R., Rog, David, Tallantyre, Emma C. ORCID: https://orcid.org/0000-0002-3760-6634, Nicholas, Richard, Morriss, Richard, Evangelou, Nikos and das Nair, Roshan 2022. Mental health of people with multiple sclerosis during the COVID-19 outbreak: a prospective cohort and cross-sectional case-control study of the UK MS Register. Multiple Sclerosis Journal 28 (7) , pp. 1060-1071. 10.1177/13524585211020435

Topcu, Gogem, Smith, Laura, Mhizha-Murira, Jacqueline, Goulden, Nia, Hoare, Zoe, Drummond, Avril, Fitzsimmons, Deborah, Evangelou, Nikos, Schmierer, Klaus, Tallantyre, Emma C ORCID: https://orcid.org/0000-0002-3760-6634, Leighton, Paul, Allen-Philbey, Kimberley, Stennett, Andrea, Bradley, Paul, Bale, Clare, Turton, James and das Nair, Roshan 2022. Neuropsychological evaluation and rehabilitation in multiple sclerosis (NEuRoMS): Protocol for a mixed-methods, multi-centre feasibility randomised controlled trial. Pilot and Feasibility Studies 8 , 123. 10.1186/s40814-022-01073-5

Allman, M., Tallantyre, E. ORCID: https://orcid.org/0000-0002-3760-6634 and Robertson, N. P. ORCID: https://orcid.org/0000-0002-5409-4909 2022. Response to SARS-CoV-2 vaccination in multiple sclerosis patients on disease modifying therapies. Journal of Neurology 269 (4) , pp. 2259-2261. 10.1007/s00415-022-11053-7

Wood, Callum H., Robertson, Neil ORCID: https://orcid.org/0000-0002-5409-4909, Min Htet, Zin and Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634 2022. Incidence of persistent lymphopenia in people with multiple sclerosis on dimethyl fumarate. Multiple Sclerosis and Related Disorders 58 , 103492. 10.1016/j.msard.2022.103492

Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634, Vickaryous, Nicola, Anderson, Valerie, Asardag, Aliye Nazli, Baker, David, Bestwick, Jonathan, Bramhall, Kath, Chance, Randy, Evangelou, Nikos, George, Katila, Giovannoni, Gavin, Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567, Grant, Leanne, Harding, Katherine E, Hibbert, Aimee, Ingram, Gillian, Jones, Meleri, Kang, Angray S, Loveless, Samantha ORCID: https://orcid.org/0000-0002-5124-4115, Moat, Stuart J, Robertson, Neil ORCID: https://orcid.org/0000-0002-5409-4909, Schmierer, Klaus, Scurr, Martin ORCID: https://orcid.org/0000-0002-4120-0688, Shah, Sita Navin, Simmons, Jessica, Upcott, Matthew, Willis, Mark ORCID: https://orcid.org/0000-0003-3024-6063, Jolles, Stephen and Dobson, Ruth 2022. COVID-19 vaccine response in people with multiple sclerosis. Annals of Neurology 91 (1) , pp. 89-100. 10.1002/ana.26251

Busse, Monica ORCID: https://orcid.org/0000-0002-5331-5909, Playle, Rebecca ORCID: https://orcid.org/0000-0002-2989-1092, Latchem-Hastings, Julie ORCID: https://orcid.org/0000-0001-6738-916X, Button, Kate ORCID: https://orcid.org/0000-0003-1073-9901, Lowe, Rachel, Barlow, Christy ORCID: https://orcid.org/0000-0001-5759-0310, Lloyd, Barry ORCID: https://orcid.org/0000-0003-4763-1726, Dean-Young, Andrew, Poile, Vincent, Dawes, Helen, Davies, Freya ORCID: https://orcid.org/0000-0002-6956-1100, O'Halloran, Rhian, Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634, Edwards, Adrian ORCID: https://orcid.org/0000-0002-6228-4446, Wood, Fiona ORCID: https://orcid.org/0000-0001-7397-4074 and Jones, Fiona 2022. A web-based life-style, exercise and activity intervention for people with progressive multiple sclerosis results of a single-arm feasibility study. Multiple Sclerosis and Related Disorders 57 , 103388. 10.1016/j.msard.2021.103388

Middleton, R. M., Craig, E. M., Rodgers, W .J., Tuite-Dalton, K., Garjani, A., Evangelou, N., das Nair, R., Hunter, R., Tallantyre, E. C. ORCID: https://orcid.org/0000-0002-3760-6634, Cauchi, M., Cairn, C., Paling, D., Fuller, S., McDonnell, G., Petherham, K., Liu, B., Nock, U., Ingram, G., Brownlee, W., Taylor, J. and Nicholas, R. 2021. COVID-19 in Multiple Sclerosis: clinically reported outcomes from the UK Multiple Sclerosis Register. Multiple Sclerosis and Related Disorders 56 , 103317. 10.1016/j.msard.2021.103317

Fernandes, Linford, Allen, Christopher Martin, Williams, Thomas, Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634, Evangelou, Nikos, Chataway, Jeremy and Ford, Helen L. 2021. The contemporary role of MRI in the monitoring and management of people with multiple sclerosis in the UK. Multiple Sclerosis and Related Disorders 55 , 103190. 10.1016/j.msard.2021.103190

Chamberland, Maxime ORCID: https://orcid.org/0000-0001-7064-0984, Winter, Mia, Brice, Thomas A. W., Jones, Derek K. ORCID: https://orcid.org/0000-0003-4409-8049 and Tallantyre, Emma C. ORCID: https://orcid.org/0000-0002-3760-6634 2021. Beyond lesion-load: tractometry-based metrics for characterizing white matter lesions within fibre pathways. Presented at: MICCAI 2020 International Workshop on Computational Diffusion MRI (CDMRI 2020), Virtual, 8 October 2020. Published in: Gyori, Noemi, Hutter, Jana, Nath, Vishwesh, Palombo, Marco, Pizzolato, Marco and Zhang, Fan eds. Computational Diffusion MRI: International MICCAI Workshop, Lima, Peru, October 2020. Mathematics and Visualization pp. 227-237. 10.1007/978-3-030-73018-5_18

Winter, Mia, Tallantyre, Emma C. ORCID: https://orcid.org/0000-0002-3760-6634, Brice, Thomas A. W., Robertson, Neil P. ORCID: https://orcid.org/0000-0002-5409-4909, Jones, Derek K. ORCID: https://orcid.org/0000-0003-4409-8049 and Chamberland, Maxime ORCID: https://orcid.org/0000-0001-7064-0984 2021. Tract-specific MRI measures explain learning and recall differences in multiple sclerosis. Brain Communications 3 (2) , fcab065. 10.1093/braincomms/fcab065

Garjani, Afagh, Middleton, Rodden, Tuite-Dalton, Katherine, Coles, Alasdair, Dobson, Ruth, Duddy, Martin, Hughes, Stella, Pearson, Owen, Rog, David, Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634, das Nair, Roshan, Nicholas, Richard and Evangelou, Nikos 2021. COVID-19 is associated with new symptoms of multiple sclerosis that are prevented by disease modifying therapies. Multiple Sclerosis and Related Disorders 52 , 102939. 10.1016/j.msard.2021.102939

Hares, Kelly, Kemp, K., Loveless, S. ORCID: https://orcid.org/0000-0002-5124-4115, Rice, C. M., Scolding, N., Tallantyre, E. ORCID: https://orcid.org/0000-0002-3760-6634, Robertson, N. ORCID: https://orcid.org/0000-0002-5409-4909 and Wilkins, A. 2021. KIF5A and the contribution of susceptibility genotypes as a predictive biomarker for multiple sclerosis. Journal of Neurology 268 , pp. 2175-2184. 10.1007/s00415-020-10373-w

MacIver, Claire Louise, Ebden, Sian and Tallantyre, Emma C ORCID: https://orcid.org/0000-0002-3760-6634 2021. MRI: how to understand it. Practical Neurology 21 (3) , pp. 216-224. 10.1136/practneurol-2020-002905

Lipp, Ilona, Foster, Catherine ORCID: https://orcid.org/0000-0003-1609-9458, Stickland, Rachael ORCID: https://orcid.org/0000-0003-3398-4272, Sgarlata, Eleonora, Tallantyre, Emma C. ORCID: https://orcid.org/0000-0002-3760-6634, Davidson, Alison E., Robertson, Neil P. ORCID: https://orcid.org/0000-0002-5409-4909, Jones, Derek K. ORCID: https://orcid.org/0000-0003-4409-8049, Wise, Richard G. ORCID: https://orcid.org/0000-0003-1700-2144 and Tomassini, Valentina ORCID: https://orcid.org/0000-0002-7368-6280 2021. Predictors of training-related improvement in visuomotor performance in patients with multiple sclerosis: a behavioural and MRI study. Multiple Sclerosis 7 (7) , pp. 1088-1101. 10.1177/1352458520943788

Latchem-Hastings, Julie ORCID: https://orcid.org/0000-0001-6738-916X, Randell, Elizabeth ORCID: https://orcid.org/0000-0002-1606-3175, Button, Kate ORCID: https://orcid.org/0000-0003-1073-9901, Jones, Fiona, Lowe, Rachel, Davies, Helen ORCID: https://orcid.org/0000-0002-6956-1100, Wood, Fiona ORCID: https://orcid.org/0000-0001-7397-4074, Davies, Freya ORCID: https://orcid.org/0000-0002-6956-1100, Poile, Vincent, O'Halloran, Rhian, Stensland, Barbara, Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634, Playle, Rebecca ORCID: https://orcid.org/0000-0002-2989-1092, Edwards, Adrian ORCID: https://orcid.org/0000-0002-6228-4446 and Busse, Monica ORCID: https://orcid.org/0000-0002-5331-5909 2021. Lifestyle, exercise and activity package for people living with progressive multiple sclerosis (LEAP-MS): protocol for a single-arm feasibility study. Pilot and Feasibility Studies 7 , 111. 10.1186/s40814-021-00852-w

Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634, Evans, Nia, Parry-Jones, Jack, Morgan, Matt, Jones, Ceri and Ingram, Wendy 2021. Neurological updates: neurological complications of CAR-T therapy. Journal of Neurology 268 , pp. 1544-1554. 10.1007/s00415-020-10237-3

Busse, Monica ORCID: https://orcid.org/0000-0002-5331-5909, Latchem-Hastings, Julie ORCID: https://orcid.org/0000-0001-6738-916X, Button, Kate ORCID: https://orcid.org/0000-0003-1073-9901, Poile, Vince, Davies, Freya ORCID: https://orcid.org/0000-0002-6956-1100, O'Halloran, Rhian, Stensland, Barbara, Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634, Lowe, Rachel, Wood, Fiona ORCID: https://orcid.org/0000-0001-7397-4074, Dawes, Helen, Edwards, Adrian ORCID: https://orcid.org/0000-0002-6228-4446 and Jones, Fiona 2021. A web-based physical activity intervention for people with progressive Multiple Sclerosis: application of consensus-based intervention development guidance. BMJ Open 11 (3) , e045378. 10.1136/bmjopen-2020-045378

Evangelou, Nikos, Garjani, Afagh, dasNair, Roshan, Hunter, Rachael, Tuite-Dalton, Katherine A, Craig, Elaine M, Rodgers, William J, Coles, Alasdair, Dobson, Ruth, Duddy, Martin, Ford, David Vincent, Hughes, Stella, Pearson, Owen, Middleton, Linda A, Rog, David, Tallantyre, Emma Clare ORCID: https://orcid.org/0000-0002-3760-6634, Friede, Tim, Middleton, Rodden M and Nicholas, Richard 2021. Self-diagnosed COVID-19 in people with multiple sclerosis: a community-based cohort of the UK MS Register. Journal of Neurology, Neurosurgery and Psychiatry 92 , pp. 107-109. 10.1136/jnnp-2020-324449

Allen-Philbey, K., De Trane, S., Mao, Z., Álvarez-González, C., Mathews, J., MacDougall, A., Stennett, A., Zhou, X., Yildiz, O., Adams, A., Bianchi, L., Blain, C., Chapman, C., Chung, K., Constantinescu, C. S., Dalton, C., Farrell, R. A., Fisniku, L., Ford, H., Gran, B., Hobart, J., Khaleeli, Z., Mattoscio, M., Pavitt, S., Pearson, O., Peruzzotti-Jametti, L., Scalfari, A., Sharrack, B., Silber, E., Tallantyre, E. ORCID: https://orcid.org/0000-0002-3760-6634, Webb, S., Turner, B. P., Marta, M., Gnanapavan, S., Juliusson, G., Giovannoni, G., Baker, D. and Schmierer, K. 2021. Subcutaneous cladribine to treat multiple sclerosis: Experience in 208 patients. Therapeutic Advances in Neurological Disorders 14 , pp. 1-16. 10.1177/17562864211057661

Zelek, Wioleta Milena, Fathalla, Dina, Morgan, Angharad ORCID: https://orcid.org/0000-0003-4075-7676, Touchard, Samuel, Loveless, Samantha ORCID: https://orcid.org/0000-0002-5124-4115, Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634, Robertson, Neil P. ORCID: https://orcid.org/0000-0002-5409-4909 and Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 2020. Cerebrospinal fluid complement system biomarkers in demyelinating disease. Multiple Sclerosis 26 (14) , pp. 1929-1937. 10.1177/1352458519887905

Anderson, Valerie, Bentley, Emily, Loveless, Sam ORCID: https://orcid.org/0000-0002-5124-4115, Bianchi, Lucia, Harding, Katharine E., Wynford-Thomas, Ray A., Joseph, Fady, Giovannoni, Gavin, Gnanapavan, Sharmilee, Robertson, Neil P. ORCID: https://orcid.org/0000-0002-5409-4909, Marta, Monica and Tallantyre, Emma C. ORCID: https://orcid.org/0000-0002-3760-6634 2020. Serum neurofilament-light concentration and real-world outcome in MS. Journal of the Neurological Sciences 417 , 117079. 10.1016/j.jns.2020.117079

Ontaneda, Daniel, Tallantyre, Emma C. ORCID: https://orcid.org/0000-0002-3760-6634, Raza, Praneeta C., Planchon, Sarah M., Nakamura, Kunio, Miller, Deborah, Hersh, Carrie, Craner, Mathew, Bale, Clare, Chaudhry, Burhan, Gunzler, Douglas D., Love, Thomas E., Gerry, Stephen, Coles, Alasdair, Cohen, Jeffrey A. and Evangelou, Nikos 2020. Determining the effectiveness of early intensive versus escalation approaches for the treatment of relapsing-remitting multiple sclerosis: The DELIVER-MS study protocol. Contemporary Clinical Trials 95 10.1016/j.cct.2020.106009

Saxena, Gauri, Moore, James, Jones, Meleri, Pryce, Gareth, Ali, Liaqat, Leisegang, Georgia, Vijay, Vivek, Loveless, Samantha ORCID: https://orcid.org/0000-0002-5124-4115, Robertson, Neil ORCID: https://orcid.org/0000-0002-5409-4909, Schmierer, Klaus, Giovannoni, Gavin, Gnananpavan, Sharmilee, Baker, David, Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634 and Kang, Angray 2020. Detecting and predicting neutralization of alemtuzumab responses in multiple sclerosis. Neurology, Neuroimmunology and Neuroinflammation 7 (4) , e767. 10.1212/NXI.0000000000000767

Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634, Castle, Daniel, Karamura, Paul, Brice, Thomas, Joseph, Fady, Harding, Katharine and Robertson, Neil ORCID: https://orcid.org/0000-0002-5409-4909 2020. Eligibility and implementation of disease-modifying therapy for primary progressive multiple sclerosis in a UK cohort. Multiple Sclerosis and Related Disorders 42 , 102056. 10.1016/j.msard.2020.102056

Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634, DPhil, Nikos, Chaudhry, Burham, Gray, Emma, LaRocca, Nicolas, Pavitt, Sue, Millar, Deborah, Planchon, Sarah, Ontaneda, Daniel and Manzano, Ana 2020. Achieving effective patient and public involvement in international clinical trials in neurology. Neurology 10 (3) , pp. 265-272. 10.1212/CPJ.0000000000000739

Lipp, Ilona, Parker, Greg D., Tallantyre, Emma C. ORCID: https://orcid.org/0000-0002-3760-6634, Goodall, Alex, Grama, Steluta, Patitucci, Eleonora, Heveron, Phoebe, Tomassini, Valentina ORCID: https://orcid.org/0000-0002-7368-6280 and Jones, Derek K. ORCID: https://orcid.org/0000-0003-4409-8049 2020. Tractography in the presence of multiple sclerosis lesions. NeuroImage 209 , 116471. 10.1016/j.neuroimage.2019.116471

Allen, Christopher M., Feng, Jenny J., Willis, Mark D. ORCID: https://orcid.org/0000-0003-3024-6063, McGinley, Marisa, Ontaneda, Daniel, Tallantyre, Emma C. ORCID: https://orcid.org/0000-0002-3760-6634 and Evangelou, Nikos 2020. Clinical observation during alemtuzumab administration. Multiple Sclerosis and Related Disorders 37 , 101412. 10.1016/j.msard.2019.101412

Davda, Nikunj, Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634 and Robertson, Neil P. ORCID: https://orcid.org/0000-0002-5409-4909 2019. Early MRI predictors of prognosis in multiple sclerosis. Journal of Neurology 266 (12) , pp. 3171-3173. 10.1007/s00415-019-09589-2

Ontaneda, Daniel, Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634, Kalincik, Tomas, Planchon, Sarah M and Evangelou, Nikos 2019. Early highly effective versus escalation treatment approaches in relapsing multiple sclerosis. Lancet Neurology 18 (10) , pp. 973-980. 10.1016/S1474-4422(19)30151-6

Abdullah, Ali Adel Ne'ma and Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634 2019. HSV-2 radiculitis: An unusual presentation mere days after genital infection. Clinical Neurology and Neurosurgery 185 , 105429. 10.1016/j.clineuro.2019.105429

Castle, Daniel, Wynford-Thomas, Ray, Loveless, Sam ORCID: https://orcid.org/0000-0002-5124-4115, Bentley, Emily, Howell, Owain W and Tallantyre, Emma C ORCID: https://orcid.org/0000-0002-3760-6634 2019. Using biomarkers to predict clinical outcomes in multiple sclerosis. Practical Neurology 19 (4) , pp. 342-349. 10.1136/practneurol-2018-002000

Lipp, Ilona, Jones, Derek K. ORCID: https://orcid.org/0000-0003-4409-8049, Bells, Sonya ORCID: https://orcid.org/0000-0001-8688-1571, Sgarlata, Eleonora, Foster, Catherine, Stickland, Rachael ORCID: https://orcid.org/0000-0003-3398-4272, Davidson, Alison E., Tallantyre, Emma C. ORCID: https://orcid.org/0000-0002-3760-6634, Robertson, Neil P. ORCID: https://orcid.org/0000-0002-5409-4909, Wise, Richard C. ORCID: https://orcid.org/0000-0003-1700-2144 and Tomassini, Valentina ORCID: https://orcid.org/0000-0002-7368-6280 2019. Comparing MRI metrics to quantify white matter microstructural damage in multiple sclerosis. Human Brain Mapping 40 (10) , pp. 2917-2932. 10.1002/hbm.24568

Harding, Katharine, Williams, Owain, Willis, Mark ORCID: https://orcid.org/0000-0003-3024-6063, Hrastelj, James ORCID: https://orcid.org/0000-0002-7991-5259, Rimmer, Anthony, Joseph, Fady, Tomassini, Valentina ORCID: https://orcid.org/0000-0002-7368-6280, Wardle, Mark, Pickersgill, Trevor, Robertson, Neil ORCID: https://orcid.org/0000-0002-5409-4909 and Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634 2019. Clinical outcomes of escalation vs early intensive disease-modifying therapy in patients with multiple sclerosis. JAMA Neurology 76 (5) , pp. 536-541. 10.1001/jamaneurol.2018.4905

Whittam, Daniel H, Tallantyre, Emma C ORCID: https://orcid.org/0000-0002-3760-6634, Jolles, Stephen, Huda, Saif, Moots, Robert J, Kim, Ho Jin, Robertson, Neil P ORCID: https://orcid.org/0000-0002-5409-4909, Cree, Bruce A C and Jacob, Anu 2019. Rituximab in neurological disease: principles, evidence and practice. Practical Neurology 19 (1) , pp. 5-10. 10.1136/practneurol-2018-001899

Robertson, JA and Tallantyre, EC ORCID: https://orcid.org/0000-0002-3760-6634 2018. Nerve sheath tumours. Journal of Neurology 265 (12) , pp. 3034-3035. 10.1007/s00415-018-9098-y

Tallantyre, Emma C. ORCID: https://orcid.org/0000-0002-3760-6634, Robertson, Neil P. ORCID: https://orcid.org/0000-0002-5409-4909 and Jolles, Stephen 2018. Secondary antibody deficiency in neurology. Current Opinion in Allergy and Clinical Immunology 18 (6) , pp. 481-488. 10.1097/ACI.0000000000000485

Beesley, Rebecca, Anderson, Valerie, Harding, Katharine E, Joseph, Fady, Tomassini, Valentina ORCID: https://orcid.org/0000-0002-7368-6280, Pickersgill, Trevor P, Robertson, Neil P ORCID: https://orcid.org/0000-0002-5409-4909 and Tallantyre, Emma C ORCID: https://orcid.org/0000-0002-3760-6634 2018. Impact of the 2017 revisions to McDonald criteria on the diagnosis of Multiple Sclerosis. Multiple Sclerosis 24 (13) , pp. 1786-1787. 10.1177/1352458518778007

Harding, Katharine, Anderson, Valerie, Williams, Owain, Willis, Mark ORCID: https://orcid.org/0000-0003-3024-6063, Butterworth, Sara, Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634, Joseph, Fady, Wardle, Mark, Pickersgill, Trevor and Robertson, Neil ORCID: https://orcid.org/0000-0002-5409-4909 2018. A contemporary study of mortality in the multiple sclerosis population of south east Wales. Multiple Sclerosis and Related Disorders 25 , pp. 186-191. 10.1016/j.msard.2018.08.001

Tallantyre, Emma Clare ORCID: https://orcid.org/0000-0002-3760-6634, Major, Paula C., Atherton, Michael J., Davies, W. Adam, Joseph, Fady, Tomassini, Valentina ORCID: https://orcid.org/0000-0002-7368-6280, Pickersgill, Trevor P., Harding, Katharine E., Willis, Mark Douglas ORCID: https://orcid.org/0000-0003-3024-6063, Winter, Mia and Robertson, Neil P. ORCID: https://orcid.org/0000-0002-5409-4909 2018. How common is truly benign MS in a UK population? Journal of Neurology, Neurosurgery and Psychiatry 90 , pp. 522-528. 10.1136/jnnp-2018-318802

Alsaeed, Meshari, Harding, Katharine, Williams, O. H., Willis, Mark ORCID: https://orcid.org/0000-0003-3024-6063, Hrastelj, James ORCID: https://orcid.org/0000-0002-7991-5259, Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634, Joseph, Fady, Wardle, Mark, Pickersgill, T. P. and Robertson, Neil ORCID: https://orcid.org/0000-0002-5409-4909 2018. Multiple sclerosis: long-term outcomes in ethnic minorities. analysis of a UK population-based registry. European Journal of Neurology 25 (4) , pp. 701-704. 10.1111/ene.13571

Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634, Whittam, D. H., Jolles, Stephen, Paling, D., Constantinescu, C., Robertson, Neil ORCID: https://orcid.org/0000-0002-5409-4909 and Jacob, A. 2018. Secondary antibody deficiency: a complication of anti-CD20 therapy for neuroinflammation. Journal of Neurology 265 (5) , pp. 1115-1122. 10.1007/s00415-018-8812-0

Willis, Mark ORCID: https://orcid.org/0000-0003-3024-6063, Pearson, Owen, Illes, Zsolt, Sejbaek, Tobias, Nielson, Christian, Duddy, Martin, Petheram, Kate, van Munster, Casper, Killestein, Joep, Malmestrom, Clas, Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634 and Robertson, Neil ORCID: https://orcid.org/0000-0002-5409-4909 2017. An observational study of alemtuzumab following fingolimod for multiple sclerosis. Neuroimmunology and Neuroinflammation 4 (2) , E320. 10.1212/NXI.0000000000000320

Tallantyre, Emma C. ORCID: https://orcid.org/0000-0002-3760-6634 and Robertson, Neil Patrick ORCID: https://orcid.org/0000-0002-5409-4909 2016. Continuous evolution of magnetic resonance imaging in multiple sclerosis. Journal of Neurology 263 (4) , pp. 835-837. 10.1007/s00415-016-8099-y

Tallantyre, Emma C. ORCID: https://orcid.org/0000-0002-3760-6634, Wardle, Mark and Robertson, Neil ORCID: https://orcid.org/0000-0002-5409-4909 2016. How to run a multiple sclerosis relapse clinic. Practical Neurology 16 (1) , pp. 62-69. 10.1136/practneurol-2015-001214

Thomas, Rhys Huw ORCID: https://orcid.org/0000-0003-2062-8623, Devine, Helen, Donnelly, Ann, Foulkes, Alexander, Galtrey, Clare, Khaleeli, Zhaleh, Lawrence, Joanne, Novak, Marianne, Redgrave, Jessica and Tallantyre, Emma C. ORCID: https://orcid.org/0000-0002-3760-6634 2015. Why neurology? The career choices of current UK neurology trainees [Conference Abstract]. Journal of Neurology, Neurosurgery & Psychiatry 86 (11) , e4. 10.1136/jnnp-2015-312379.42

Williams, Owain, Tallantyre, Emma C. ORCID: https://orcid.org/0000-0002-3760-6634 and Robertson, Neil ORCID: https://orcid.org/0000-0002-5409-4909 2015. Traumatic brain injury: pathophysiology, clinical outcome and treatment. Journal of Neurology 262 (5) , pp. 1394-1396. 10.1007/s00415-015-7741-4

Tallantyre, Emma ORCID: https://orcid.org/0000-0002-3760-6634, Causon, E. G., Harding, Katharine, Pickersgill, T. P. and Robertson, Neil ORCID: https://orcid.org/0000-0002-5409-4909 2015. The aetiology of acute neurological decline in multiple sclerosis: Experience from an open-access clinic. Multiple Sclerosis Journal 21 (1) , pp. 67-75. 10.1177/1352458514538333

Tallantyre, Emma C. ORCID: https://orcid.org/0000-0002-3760-6634 and Robertson, Neil ORCID: https://orcid.org/0000-0002-5409-4909 2015. Acute stroke management. Journal of Neurology 262 (1) , pp. 239-242. 10.1007/s00415-014-7607-1

Tallantyre, Emma C. ORCID: https://orcid.org/0000-0002-3760-6634 and Robertson, Neil ORCID: https://orcid.org/0000-0002-5409-4909 2013. Autism and intellectual disability. Journal of Neurology 260 (3) , pp. 936-939. 10.1007/s00415-013-6861-y