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Number of items: 45.

Gilbert, Sophie J., Soul, Jamie, Hao, Yao, Lin, Hua, Piróg, Katarzyna A., Coxhead, Jonathan, Patel, Krutik, Barter, Matt J., Young, David A. and Blain, Emma J. ORCID: https://orcid.org/0000-0001-8944-4254 2024. Comparative transcriptomic analysis of articular cartilage of post-traumatic osteoarthritis mouse models. Disease Models & Mechanisms 10.1242/dmm.050583
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Kalsoum, Raneem, Minns Lowe, Catherine J., Gilbert, Sophie, McCaskie, Andrew W., Snow, Martyn, Wright, Karina, Bruce, Geoff, Mason, Deborah J. ORCID: https://orcid.org/0000-0002-8666-6094 and Watt, Fiona E. 2024. A mixed-methods approach exploring acceptability and feasibility of trials designed to test drugs targeting prevention of post-traumatic osteoarthritis after knee injury. Bone & Joint Research 13 (9) , pp. 513-524. 10.1302/2046-3758.139.BJR-2024-0109
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Gilbert, Sophie J., Jones, Ryan, Egan, Ben J., Bonnet, Cleo Selina, Evans, Sam L. ORCID: https://orcid.org/0000-0003-3664-2569 and Mason, Deborah J. ORCID: https://orcid.org/0000-0002-8666-6094 2024. Investigating mechanical and inflammatory pathological mechanisms in osteoarthritis using MSC-derived osteocyte-like cells in 3D. Frontiers in Endocrinology 15 , 1359052. 10.3389/fendo.2024.1359052
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Gilbert, Sophie J., Soul, Jamie, Hao, Yao, Lin, Hua, Piróg, Katarzyna A., Coxhead, Jonathan, Patel, Krutik, Barter, Matt J., Young, David A. and Blain, Emma J. ORCID: https://orcid.org/0000-0001-8944-4254 2024. Comparative transcriptomic analysis of articular cartilage of post-traumatic osteoarthritis mouse models. Disease Models & Mechanisms 10.1242/dmm.050583
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Gilbert, S. J., Blain, E. J. ORCID: https://orcid.org/0000-0001-8944-4254 and Mason, D. J. ORCID: https://orcid.org/0000-0002-8666-6094 2022. Interferon-gamma modulates articular chondrocyte and osteoblast metabolism through protein kinase R-independent and dependent mechanisms. Biochemistry and Biophysics Reports 32 , 101323. 10.1016/j.bbrep.2022.101323
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Gilbert, Sophie Jane, Bonnet, Cleo Selina and Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254 2021. Mechanical cues: bidirectional reciprocity in the extracellular matrix drives mechano-signalling in articular cartilage. International Journal of Molecular Sciences 22 (24) , 13595. 10.3390/ijms222413595
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Tobias, Jonathan H., Duncan, Emma L., Kague, Erika, Hammond, Chrissy L., Gregson, Celia L., Bassett, Duncan, Williams, Graham R., Min, Josine L., Gaunt, Tom R., Karasik, David, Ohlsson, Claes, Rivadeneira, Fernando, Edwards, James R., Hannan, Fadil M., Kemp, John P., Gilbert, Sophie J., Alonso, Nerea, Hassan, Neelam, Compston, Juliet E. and Ralston, Stuart H. 2021. Opportunities and challenges in functional genomics research in osteoporosis: report from a workshop held by the Causes Working Group of the Osteoporosis and Bone Research Academy of the Royal Osteoporosis Society on October 5th 2020. Frontiers in Endocrinology 11 , 630875. 10.3389/fendo.2020.630875
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Stadnik, Paulina S., Gilbert, Sophie J., Tarn, Jessica, Charlton, Sarah, Skelton, Andrew J., Barter, Matthew J., Duance, Victor C. ORCID: https://orcid.org/0000-0002-7555-2016, Young, David A. and Blain, Emma J. ORCID: https://orcid.org/0000-0001-8944-4254 2021. Regulation of microRNA‐221, ‐222, ‐21 and ‐27 in articular cartilage subjected to abnormal compressive forces. Journal of Physiology 599 (1) , pp. 143-155. 10.1113/JP279810
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Bonnet, Cleo S., Gilbert, Sophie J., Blain, Emma J. ORCID: https://orcid.org/0000-0001-8944-4254, Williams, Anwen S. ORCID: https://orcid.org/0000-0001-6118-020X and Mason, Deborah J. ORCID: https://orcid.org/0000-0002-8666-6094 2020. AMPA/kainate glutamate receptor antagonists prevent posttraumatic osteoarthritis. JCI Insight 5 (13) , e134055. 10.1172/jci.insight.134055
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Gilbert, Sophie J., Bonnet, Cleo S., Stadnik, Paulina, Duance, Victor C. ORCID: https://orcid.org/0000-0002-7555-2016, Mason, Deborah J. ORCID: https://orcid.org/0000-0002-8666-6094 and Blain, Emma J. ORCID: https://orcid.org/0000-0001-8944-4254 2018. Inflammatory and degenerative phases resulting from anterior cruciate rupture in a non-invasive murine model of post-traumatic osteoarthritis. Journal of Orthopaedic Research 36 (8) , pp. 2118-2127. 10.1002/jor.23872
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Gilbert, Sophie and Blain, Emma ORCID: https://orcid.org/0000-0001-8944-4254 2018. Cartilage mechanobiology: how chondrocytes respond to mechanical load. Verbruggen, Stefaan, ed. Mechanobiology in Health and Disease, London UK: Elsevier, pp. 99-126.

Al-Sabah, Ayesha, Stadnik, Paulina, Gilbert, Sophie, Duance, Victor ORCID: https://orcid.org/0000-0002-7555-2016 and Blain, Emma ORCID: https://orcid.org/0000-0001-8944-4254 2016. Importance of reference gene selection for articular cartilage mechanobiology studies. Osteoarthritis and Cartilage 24 (4) , pp. 719-730. 10.1016/j.joca.2015.11.007
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Bonnet, Cleo S., Williams, Anwen S. ORCID: https://orcid.org/0000-0001-6118-020X, Gilbert, Sophie J., Harvey, Ann K., Evans, Bronwen A. ORCID: https://orcid.org/0000-0002-3082-1008 and Mason, Deborah J. ORCID: https://orcid.org/0000-0002-8666-6094 2014. AMPA/kainate glutamate receptors contribute to inflammation, degeneration and pain related behaviour in inflammatory stages of arthritis. Annals of the Rheumatic Diseases 74 , pp. 242-251. 10.1136/annrheumdis-2013-203670
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Gilbert, Sophie J., Meakin, Lee B., Bonnet, Cleo S., Nowell, Mari A., Ladiges, Warren C., Morton, John, Duance, Victor C. ORCID: https://orcid.org/0000-0002-7555-2016 and Mason, Deborah J. ORCID: https://orcid.org/0000-0002-8666-6094 2014. Deletion of P58IPK, the cellular inhibitor of the protein kinases PKR and PERK, causes bone changes and joint degeneration in mice. Frontiers in Endocrinology 5 , 174. 10.3389/fendo.2014.00174
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Bonnet, Cleo, Williams, A. S., Gilbert, Sophie Jane, Harvey, Ann, Evans, Bronwen Alice James ORCID: https://orcid.org/0000-0002-3082-1008 and Mason, Deborah Jane ORCID: https://orcid.org/0000-0002-8666-6094 2014. NBQX, a glutamate receptor antagonist, alleviates inflammation, pathology and gait abnormalities in a rat model of inflammatory arthritis. International Journal of Experimental Pathology 95 (3) , A5-A6. 10.1111/iep.12078

Gilbert, Sophie Jane, Meakin, L. B., Mason, Deborah Jane ORCID: https://orcid.org/0000-0002-8666-6094, Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 and Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254 2014. The use of a non-invasive murine knee joint loading model to identify mechano-regulated genes in vivo. International Journal of Experimental Pathology 95 (3) , A11-A12. 10.1111/iep.12078

Bonnet, Cleo, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Harvey, Ann, Gilbert, Sophie Jane, Moideen, Abdul Nazeer, Nowell, Mari Ann and Mason, Deborah Jane ORCID: https://orcid.org/0000-0002-8666-6094 2012. Intra-articular AMPA/kainate glutamate receptor antagonists alleviate inflammation, pain and pathology in rat antigen induced arthritis [Abstract]. Osteoporosis International 23 , S527-S527.

Gilbert, Sophie Jane, Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254, Al-Sabah, Ayesha, Zhang, Yadan, Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 and Mason, Deborah Jane ORCID: https://orcid.org/0000-0002-8666-6094 2012. Protein kinase R plays a pivotal role in oncostatin M and interleukin-1 signalling in bovine articular cartilage chondrocytes. European Cells and Materials 23 , pp. 41-57.

Parsons, P., Gilbert, Sophie Jane, Vaughan-Thomas, A., Sorrell, D. A., Notman, Rebecca, Bishop, M, Hayes, Anthony Joseph, Mason, Deborah Jane ORCID: https://orcid.org/0000-0002-8666-6094 and Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 2011. Type IX collagen interacts with fibronectin providing an important molecular bridge in articular cartilage. Journal of Biological Chemistry 286 (40) , pp. 34986-34997. 10.1074/jbc.M111.238188

Khan, Ilyas Mahmood, Gonzalez, Lee, Gilbert, Sophie Jane, Singhrao, S. K., Burdon, D., Hollander, A. P., Duance, Victor ORCID: https://orcid.org/0000-0002-7555-2016, Archer, Charles William, Francis, L. and Conlan, R. S. 2011. Interleukin-1β enhances cartilage-to-cartilage integration. European Cells and Materials 22 , pp. 190-201.

Parsons, Philippa, Gilbert, Sophie Jane, Vaughan-Thomas, Anne, Sorrell, David A., Notman, Rebecca, Bishop, Mark, Mason, Deborah Jane ORCID: https://orcid.org/0000-0002-8666-6094 and Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 2011. Identification of a type IX collagen interaction with fibronectin: a molecular bridge in articular cartilage? The Journal of Biological Chemistry 286 (40) , pp. 34986-34997. 10.1074/jbc.M111.238188

Gilbert, Sophie Jane, Patel, M., Toumi, H., Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 and Mason, Deborah Jane ORCID: https://orcid.org/0000-0002-8666-6094 2010. Knockout of P58(IPK), a known inhibitor of PKR, in mice results in a degenerative phenotype in the knee joint. International Journal of Experimental Pathology 91 (2) , A34-A34. 10.1111/j.1365-2613.2009.00690.x

Singhrao, S.K., Müller, Carsten Theodor ORCID: https://orcid.org/0000-0003-0455-7132, Gilbert, Sophie Jane, Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 and Archer, Charles William 2009. An immunofluorescence method for postembedded tissue in the acrylic resin Technovit 9100 New(R) using fluorescein isothiocyanate secondary detection. Microscopy Research and Technique 72 (7) , pp. 501-506. 10.1002/jemt.20705

Gilbert, Sophie Jane, Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 and Mason, Deborah Jane ORCID: https://orcid.org/0000-0002-8666-6094 2009. A pivotal role for protein kinase R in the oncostatin m and interleukin-1 induced catabolic phenotype in bovine articular cartilage chondrocytes. International Journal of Experimental Pathology 90 (2) , A112-A112. 10.1111/j.1365-2613.2008.00644.x

Singhrao, S. K., Müller, Carsten Theodor ORCID: https://orcid.org/0000-0003-0455-7132, Gilbert, Sophie Jane, Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 and Archer, Charles William 2009. An immunofluorescence method for post-embedded tissue in acrylic resin Technovit 9100 New(R) using fluorescein isothiocyanate secondary detection marker [Abstract]. International Journal of Experimental Pathology 90 (2) , A129.

Gilbert, Sophie Jane, Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 and Mason, Deborah Jane ORCID: https://orcid.org/0000-0002-8666-6094 2009. A pivotal role for protein kinase R in the oncastatin m and interleukin-1 induced catabolic phenotype in bovine articular cartilage chondrocytes. International Journal of Experimental Pathology 90 (2) , A112-A112.

Gilbert, Sophie Jane, Singhrao, S. K., Khan, IIyas Mahmood, Gonzalez, Lee, Thomson, B. M., Burdon, D., Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 and Archer, Charles William 2009. Enhanced Tissue Integration During Cartilage Repair In Vitro Can Be Achieved by Inhibiting Chondrocyte Death at the Wound Edge. Tissue Engineering :Part A 15 (7) , pp. 1739-1749. 10.1089/ten.tea.2008.0361

Khan, Ilyas Mahmmod, Bishop, J. C., Gilbert, Sophie Jane and Archer, Charles William 2009. Clonal chondroprogenitors maintain telomerase activity and Sox9 expression during extended monolayer culture and retain chondrogenic potential. Osteoarthritis and Cartilage 17 (4) , pp. 518-528. 10.1016/j.joca.2008.08.002

Gilbert, Sophie Jane, Singhrao, S. K., Khan, I., Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 and Archer, Charles 2008. Inhibition of chondrocyte death at the wound edge enhances integrative cartilage repair. European Cells and Materials 16 , pp. 26-39.

Khan, Ilyas Mahmood, Gilbert, Sophie Jane, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Sandell, L. and Archer, Charles William 2008. Oxidative stress induces expression of osteoarthritis markers procollagen IIA and 3B3(-) in adult bovine articular cartilage. Osteoarthritis and Cartilage 16 (6) , pp. 698-707. 10.1016/j.joca.2007.10.004

Gilbert, Sophie Jane, Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254, Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 and Mason, Deborah Jane ORCID: https://orcid.org/0000-0002-8666-6094 2008. Sphingomyelinase decreases type II collagen expression in bovine articular chondrocytes via the ERK signalling pathway. Arthritis and Rheumatism 58 (1) , pp. 209-220. 10.1002/art.23172

Gilbert, Sophie Jane, Singhrao, S. K., Khan, I. M., Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 and Archer, Charles William 2008. Inhibiting chondrocyte death at the wound edge results in successful integrative cartilage repair in vitro. European Cells and Materials 16 (Supp 3) , p. 55.

Davies, L. C., Blain, Emma ORCID: https://orcid.org/0000-0001-8944-4254, Gilbert, Sophie Jane, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Duance, Victor ORCID: https://orcid.org/0000-0002-7555-2016 2008. The potential of IGF-1 and TGFβ1 for promoting “adult” articular cartilage repair: An in vitro study. Tissue Engineering Part A 14 (7) , pp. 1251-1261. 10.1089/ten.tea.2007.0211

Khan, Ilyas Mahmood, Gilbert, Sophie Jane, Singhrao, S.K, Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 and Archer, Charles William 2008. Cartilage integration: evaluation of the reasons for failure of integration during cartilage repair. (A review). European Cells & Materials 16 , pp. 26-39.

Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254, Gilbert, Sophie Jane, Hayes, Anthony Joseph and Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 2006. Disassembly of the vimentin cytoskeleton disrupts articular cartilage chondrocyte homeostasis. Matrix biology 25 (7) , pp. 398-408. 10.1016/j.matbio.2006.06.002

Gilbert, Sophie Jane, Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254, Jones, Pamela, Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 and Mason, Deborah Jane ORCID: https://orcid.org/0000-0002-8666-6094 2006. Exogenous sphingomyelinase increases collagen and sulphated glycosaminoglycan production by primary articular chondrocytes: an in vitro study. Arthritis research & therapy 8 (4) , R89. 10.1186/ar1961
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Gilbert, Sophie Jane, Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 and Mason, Deborah Jane ORCID: https://orcid.org/0000-0002-8666-6094 2006. Protein kinase R: A novel mediator of articular cartilage degradation in arthritis. Current Rheumatology Reviews 2 (1) , pp. 9-21. 10.2174/157339706775697026

Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254, Gilbert, Sophie Jane and Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 2005. An intact cytoskeleton is essential to maintain articular cartilage chondrocyte metabolism. International Journal of Experimental Pathology 86 (3) , A10-A11. 10.1111/j.0959-9673.2005.00426.x

Gilbert, Sophie Jane, Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 and Mason, Deborah Jane ORCID: https://orcid.org/0000-0002-8666-6094 2003. Does protein kinase R mediate TNF-α- and ceramide-induced increases in expression and activation of matrix metalloproteinases in articular cartilage by a novel mechanism? Arthritis Research & Therapy 6 (1) , R46-R55. 10.1186/ar1024
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Gilbert, Sophie Jane, Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 and Mason, Deborah Jane ORCID: https://orcid.org/0000-0002-8666-6094 2002. Tumour necrosis factor α up-regulates protein kinase R (PKR)-activating protein (PACT) and increases phosphorylation of PKR and eukaryotic initiation factor 2-α in articular chondrocytes. Biochemical Society Transactions 30 (6) , pp. 886-889. 10.1042/BST0300886

Gilbert, Sophie Jane, Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 and Mason, Deborah Jane ORCID: https://orcid.org/0000-0002-8666-6094 2002. Tumour necrosis factor α up-regulates protein kinase R (PKR)-activating protein (PACT) and increases phosphorylation of PKR and eukaryotic initiation factor 2-α in articular chondrocyte. Biochemical Society Transactions 30 , pp. 886-889. 10.1042/bst0300886

Blain, Emma Jane ORCID: https://orcid.org/0000-0001-8944-4254, Gilbert, Sophie Jane, Wardale, Robert John, Capper, S. J., Mason, Deborah Jane ORCID: https://orcid.org/0000-0002-8666-6094 and Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 2001. Up-regulation of matrix metalloproteinase expression and activation following cyclical compressive loading of articular cartilage in vitro. Archives of biochemistry and biophysics 396 (1) , pp. 49-55. 10.1006/abbi.2001.2575

Vaughan-Thomas, A., Gilbert, Sophie Jane and Duance, Victor ORCID: https://orcid.org/0000-0002-7555-2016 2000. Elevated levels of proteolytic enzymes in the aging human vitreous. Investigative Ophthalmology & Visual Science 41 (11) , pp. 3299-32304.

Gilbert, Sophie Jane, Wotton, P. R., Bailey, A. J., Sims, T. J. and Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 2000. Alterations in the organisation, ultrastructure and biochemistry of the myocardial collagen matrix in Doberman pinschers with dilated cardiomyopathy. Research in Veterinary Science 69 (3) , pp. 267-274. 10.1053/rvsc.2000.0423

Gilbert, Sophie Jane, Wotton, P. R., Tarlton, J. F., Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016 and Bailey, A. J. 1997. Increased expression of promatrix metalloproteinase-9 and neutrophil elastase in canine dilated cardiomyopathy. Cardiovascular Research 34 (2) , pp. 377-383. 10.1016/S0008-6363(97)00011-4

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