Browse by Current Cardiff authors

Morrin, Aisling S., Eastham, Simon, Williams, Anwen S. ORCID: https://orcid.org/0000-0001-6118-020X and Jones, Gareth W. 2023. Tracking cardiovascular comorbidity in models of chronic inflammatory disease. Jenkins, Brendan J., ed. Inflammation and Cancer, Vol. 2691. Methods in Molecular Biology, New York, NY, USA: Springer, pp. 123-137. (10.1007/978-1-0716-3331-1_10)

Gillespie, D. ORCID: https://orcid.org/0000-0002-6934-2928, Couzens, Z., de Bruin, M., Hughes, D. A., Jones, A., Ma, R., Williams, A. ORCID: https://orcid.org/0000-0001-6118-020X, Wood, F. ORCID: https://orcid.org/0000-0001-7397-4074, Blee, K., Bradshaw, H. S., Drayton, R., Knapper, C. and Hood, K. ORCID: https://orcid.org/0000-0002-5268-8631 2022. PrEP use, sexual behaviour, and PrEP adherence among men who have sex with men living in Wales prior to and during the COVID-19 pandemic. AIDS and Behavior 26 , pp. 2746-2757. 10.1007/s10461-022-03618-4

Davies, Ruth, Williams, Jessica, Sime, Katie, Jin, Hyun-Sun, Thompson, Charlotte, Jordan, Lauren, Lang, Derek, Halcox, Julian P, Ellins, Elizabeth ORCID: https://orcid.org/0000-0001-5164-6416, Jones, Gareth, Jones, Simon A. ORCID: https://orcid.org/0000-0001-7297-9711, Rose-John, Stefan, Williams, Anwen ORCID: https://orcid.org/0000-0001-6118-020X and Choy, Ernest ORCID: https://orcid.org/0000-0003-4459-8609 2021. The role of interleukin-6 trans-signalling on cardiovascular dysfunction in inflammatory arthritis. Rheumatology 60 (6) , pp. 2852-2861. 10.1093/rheumatology/keaa725

Bonnet, Cleo S., Gilbert, Sophie J., Blain, Emma J. ORCID: https://orcid.org/0000-0001-8944-4254, Williams, Anwen S. ORCID: https://orcid.org/0000-0001-6118-020X and Mason, Deborah J. ORCID: https://orcid.org/0000-0002-8666-6094 2020. AMPA/kainate glutamate receptor antagonists prevent posttraumatic osteoarthritis. JCI Insight 5 (13) , e134055. 10.1172/jci.insight.134055

Thompson, Charlotte, Davies, Ruth, Williams, Anwen ORCID: https://orcid.org/0000-0001-6118-020X, Jones, Gareth and Choy, Ernest H. S. ORCID: https://orcid.org/0000-0003-4459-8609 2020. CD28− Cells are increased in early rheumatoid arthritis and are linked with cytomegalovirus status. Frontiers in Medicine 7 , 129. 10.3389/fmed.2020.00129

Collins, Fraser L., Stone, Michael D., Turton, Jane, McCabe, Laura R., Wang, Eddie C.Y. ORCID: https://orcid.org/0000-0002-2243-4964 and Williams, Anwen S. ORCID: https://orcid.org/0000-0001-6118-020X 2019. Oestrogen-deficiency induces bone loss by modulating CD14+ monocyte and CD4+ T cell DR3 expression and serum TL1A levels. BMC Musculoskeletal Disorders 20 (1) , 326. 10.1186/s12891-019-2704-z

Williams, Anwen ORCID: https://orcid.org/0000-0001-6118-020X, Jones, Meriel G., Jonsson, Roland, Harris, Robert A. and Mulvany, Michael J. 2019. A comparison of doctoral training in biomedicine and medicine for some UK and Scandinavian graduate programmes: Learning from each other. FEBS Open Bio 9 (5) , pp. 830-839. 10.1002/2211-5463.12629

Williams, Anwen ORCID: https://orcid.org/0000-0001-6118-020X, Powell, Arfon G.M.T ORCID: https://orcid.org/0000-0002-3740-8275, Spernaes, Izabela, Basu, Pallavi, Edwards, Stephen and Edwards, Paul 2019. Mode of presentation rather than the 'weekend effect' is a major determinant of in-hospital mortality. Surgeon 17 (1) , pp. 15-18. 10.1016/j.surge.2018.04.007

Jordan, Lauren A., Erlandsson, Malin C., Fenner, Benjamin F., Davies, Ruth, Harvey, Ann K., Choy, Ernest H. ORCID: https://orcid.org/0000-0003-4459-8609, Errington, Rachel ORCID: https://orcid.org/0000-0002-8016-4376, Bokarewa, Maria I. and Williams, Anwen S. ORCID: https://orcid.org/0000-0001-6118-020X 2018. Inhibition of CCL3 abrogated precursor cell fusion and bone erosions in human osteoclast cultures and murine collagen-induced arthritis. Rheumatology 57 (11) , pp. 2042-2052. 10.1093/rheumatology/key196

Tonks, Amanda J. and Williams, Anwen S. ORCID: https://orcid.org/0000-0001-6118-020X 2018. Identifying unmet training needs for postgraduate research students in the biomedical sciences through audit of examiners' reports. International Journal of Doctoral Studies 13 , pp. 169-191. 10.28945/4003

Jones, Gareth, Hill, David, Sime, Katie and Williams, Anwen ORCID: https://orcid.org/0000-0001-6118-020X 2018. In Vivo models for inflammatory arthritis. Jenkins, B, ed. Inflammation and Cancer. Methods in Molecular Biology, Vol. 1725. Methods in Molecular Biology, New York, NY: Humana Press, pp. 101-118. (10.1007/978-1-4939-7568-6_9)

Colbeck, Emily J., Jones, Emma, Hindley, James P., Smart, Kathryn, Schulz, Ralph, Browne, Molly, Cutting, Scott, Williams, Anwen ORCID: https://orcid.org/0000-0001-6118-020X, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567, Ware, Carl F., Ager, Ann and Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 2017. Treg depletion licenses T cell-driven HEV neogenesis and promotes tumor destruction. Cancer Immunology Research 5 (11) , pp. 1005-1015. 10.1158/2326-6066.CIR-17-0131

Singh, Ravinder, Perks, William, Twohig, Jason, Kidd, Emma ORCID: https://orcid.org/0000-0001-5507-1170, Broadley, Kenneth ORCID: https://orcid.org/0000-0002-3339-2050, Farrow, S N, Williams, Anwen ORCID: https://orcid.org/0000-0001-6118-020X, Taylor, Philip ORCID: https://orcid.org/0000-0003-0163-1421 and Wang, Edward ORCID: https://orcid.org/0000-0002-2243-4964 2017. Death receptor 3 regulates distinct pathological attributes of acute versus chronic murine allergic lung inflammation. Cellular Immunology 320 , pp. 62-70. 10.1016/j.cellimm.2017.09.005

Sime, Katie, Choy, Ernest ORCID: https://orcid.org/0000-0003-4459-8609 and Williams, Anwen ORCID: https://orcid.org/0000-0001-6118-020X 2017. Alterations to adipose tissue morphology during inflammatory arthritis is indicative of vasculopathology in DBA/1 mice. Adipocyte 6 (2) , pp. 87-101. 10.1080/21623945.2017.1295174

Collins, Fraser L., Williams, Jessica O. ORCID: https://orcid.org/0000-0001-6118-020X, Bloom, Anja C., Singh, Ravinder K., Jordan, Lauren, Stone, Michael D., McCabe, Laura R., Wang, Eddie C. Y. ORCID: https://orcid.org/0000-0002-2243-4964 and Williams, Anwen S. ORCID: https://orcid.org/0000-0001-6118-020X 2017. CCL3 and MMP-9 are induced by TL1A during death receptor 3 (TNFRSF25)-dependent osteoclast function and systemic bone loss. Bone 97 , pp. 94-104. 10.1016/j.bone.2017.01.002

Williams, Anwen ORCID: https://orcid.org/0000-0001-6118-020X, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Thurner, Lorenz and Liu, Chuan-ju 2016. Novel insights into TNF receptor, DR3 and progranulin pathways in arthritis and bone remodeling. Arthritis & Rheumatology 68 (12) , pp. 2845-2856. 10.1002/art.39816

Perks, William V., Singh, Ravinder K., Jones, Gareth W., Twohig, Jason P., Williams, Anwen S. ORCID: https://orcid.org/0000-0001-6118-020X, Humphreys, Ian R. ORCID: https://orcid.org/0000-0002-9512-5337, Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421, Jones, Simon A. and Wang, Eddie C. Y. ORCID: https://orcid.org/0000-0002-2243-4964 2016. Death Receptor 3 promotes chemokine directed leukocyte recruitment in acute resolving inflammation and is essential for pathological development of mesothelial fibrosis in chronic disease. American Journal of Pathology 186 (11) , pp. 2813-2823. 10.1016/j.ajpath.2016.07.021

Williams, Jessica, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Lang, Derek and Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X 2016. Characterisation of Death Receptor 3 dependent aortic changes during inflammatory arthritis. Pharmacology Research & Perspectives 4 (4) , e0024. 10.1002/prp2.240

Knight, James C., Paisey, Stephen James ORCID: https://orcid.org/0000-0002-2274-3708, Dabkowski, Adam M., Marculescu, Cristina, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Marshall, Christopher and Cornelissen, Bart 2016. Scaling-down antibody radiolabeling reactions with zirconium-89. Dalton Transactions 45 (15) , pp. 6343-6347. 10.1039/C5DT04774A

Davies, Ruth, Iacono, Daniela, Jordan, Lauren, Williams, Jessica O., Sime, Katie, Rawlings, Charlotte, Lang, Derek, Jones, Simon ORCID: https://orcid.org/0000-0001-7297-9711, Williams, Anwen ORCID: https://orcid.org/0000-0001-6118-020X and Choy, Ernest ORCID: https://orcid.org/0000-0003-4459-8609 2016. Serum Vascular Cell Adhesion Molecule 1 levels are associated with vascular Dysfunction and increased cardiovascular risk in an animal model and patients with Rheumatoid Arthritis. Rheumatology 55 (Supp 1) , p. 54. 10.1093/rheumatology/kew102.004

Harvey, Ann K, Lelos, Mariah Jillian ORCID: https://orcid.org/0000-0001-7102-055X, Greenhill, Claire J., Jones, Ashley, Clinch, Susanne, Newton, Michael, Dunnett, Stephen Bruce ORCID: https://orcid.org/0000-0003-1826-1578, Wyatt, Sean Lee ORCID: https://orcid.org/0000-0002-0572-234X, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2016. Novel application of behavioral assays allows dissociation of joint pathology from systemic extra-articular alterations induced by inflammatory arthritis. Journal of Rheumatic Diseases and Treatment 2 (2) , 033. 10.23937/2469-5726/1510033

Bloom, Anja C., Collins, Fraser L., van't Hof, Rob J., Ryan, Elizabeth S., Jones, Emma, Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Erlandsson, Malin, Bokarewa, Maria, Aeschlimann, Daniel ORCID: https://orcid.org/0000-0003-0930-7706, Evans, Bronwen A. J. ORCID: https://orcid.org/0000-0002-3082-1008 and Williams, Anwen S. ORCID: https://orcid.org/0000-0001-6118-020X 2016. Deletion of the membrane complement inhibitor CD59a drives age and gender-dependent alterations to bone phenotype in mice. Bone 84 , pp. 253-261. 10.1016/j.bone.2015.12.014

Jones, Gareth W., Bombardieri, Michele, Greenhill, Claire J., McLeod, Louise, Nerviani, Alessandra, Rocher-Ros, Vidalba, Cardus, Anna, Williams, Anwen S. ORCID: https://orcid.org/0000-0001-6118-020X, Pitzalis, Costantino, Jenkins, Brendan J. and Jones, Simon A. ORCID: https://orcid.org/0000-0001-7297-9711 2015. Interleukin-27 inhibits ectopic lymphoid-like structure development in early inflammatory arthritis. Journal of Experimental Medicine 212 (11) , pp. 1793-1802. 10.1084/jem.20132307

Bonnet, Cleo S., Williams, Anwen S. ORCID: https://orcid.org/0000-0001-6118-020X, Gilbert, Sophie J., Harvey, Ann K., Evans, Bronwen A. ORCID: https://orcid.org/0000-0002-3082-1008 and Mason, Deborah J. ORCID: https://orcid.org/0000-0002-8666-6094 2014. AMPA/kainate glutamate receptors contribute to inflammation, degeneration and pain related behaviour in inflammatory stages of arthritis. Annals of the Rheumatic Diseases 74 , pp. 242-251. 10.1136/annrheumdis-2013-203670

Wang, Eddie C. Y. ORCID: https://orcid.org/0000-0002-2243-4964, Newton, Zarabeth, Hayward, Olivia A., Clark, Stephen R. ORCID: https://orcid.org/0000-0001-5907-9671, Collins, Fraser, Perks, William V., Singh, Ravinder K., Twohig, Jason P. and Williams, Anwen S. ORCID: https://orcid.org/0000-0001-6118-020X 2014. Regulation of early cartilage destruction in inflammatory arthritis by death receptor 3. Arthritis and Rheumatology 66 (10) , pp. 2762-2772. 10.1002/art.38770

Greenhill, Claire J., Jones, Gareth Wyn, Nowell, Mari Ann, Newton, Zarabeth, Harvey, Ann K., Moideen, Abdul Nazeer, Collins, Fraser L., Bloom, Anja C., Coll, Rebecca C., Robertson, Avril A. B., Cooper, Matthew A., Rosas, Marcela ORCID: https://orcid.org/0000-0002-9442-9638, Taylor, Philip Russel ORCID: https://orcid.org/0000-0003-0163-1421, O'Neill, Luke A., Humphreys, Ian R. ORCID: https://orcid.org/0000-0002-9512-5337, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2014. Interleukin-10 regulates the inflammasome-driven augmentation of inflammatory arthritis and joint destruction. Arthritis Research and Therapy 16 (4) , 419. 10.1186/s13075-014-0419-y

Kehoe, Oksana, Kalia, Neena, King, Sophie, Eustace, Andrew, Boyes, Charlotte, Reizes, Ofer, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Patterson, Angela and Middleton, Jim 2014. Syndecan-3 is selectively pro-inflammatory in the joint and contributes to antigen-induced arthritis in mice. Arthritis Research and Therapy 16 (4) , pp. 1-14. 10.1186/ar4610

Lauder, Sarah Nicol, Jones, Emma, Smart, Kathryn, Bloom, Anja Constanze, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Hindley, James P., Ondondo, Beatrice, Taylor, Philip Russel ORCID: https://orcid.org/0000-0003-0163-1421, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153, Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 2013. Interleukin-6 limits influenza-induced inflammation and protects against fatal lung pathology. European Journal of Immunology 43 (10) , pp. 2613-2625. 10.1002/eji.201243018

Jones, Gareth Wyn, Greenhill, C. J., Williams, J. O., Nowell, Mari Ann, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Jenkins, B. J. and Jones, S. A. 2013. Exacerbated inflammatory arthritis in response to hyperactive gp130 signalling is independent of IL-17A. Annals of the Rheumatic Diseases 72 (10) , pp. 1738-1742. 10.1136/annrheumdis-2013-203771

Greenhill, Claire J., Jones, Gareth Wyn, Nowell, Mari Ann, Harvey, Ann, Moideen, Abdul Nazeer, Collins, Fraser, Bloom, Anja Constanze, Coll, R., Rosas, Marcela ORCID: https://orcid.org/0000-0002-9442-9638, Taylor, Philip Russel ORCID: https://orcid.org/0000-0003-0163-1421, O'Neill, L. A., Humphreys, Ian R. ORCID: https://orcid.org/0000-0002-9512-5337, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2013. Interleukin 10 control of the inflammasome restricts arthritic bone erosion [Abstract]. Cytokine 63 (3) , p. 267. 10.1016/j.cyto.2013.06.105

Moideen, Abdul Nazeer, Evans, Laura, Osgood, Louise Emma, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 and Nowell, Mari Ann 2013. Characterization of enzymes involved in nicotinamide adenine dinucleotide biosynthesis in rheumatoid arthritis synovium and cytokine-stimulated synovial fibroblasts [Abstracts]. Rhuematology 52 (s1) , pp. 138-139.

Reynolds, Sophie Leanne, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Williams, H., Smale, Shaun, Stephenson, Hayden J., Amos, Nick, George, S. J., O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460 and Lang, Derek 2012. Contractile, but not endothelial, dysfunction in early inflammatory arthritis: a possible role for matrix metalloproteinase-9. British Journal of Pharmacology 167 (3) , pp. 505-514. 10.1111/j.1476-5381.2012.01988.x

Collins, Fraser, Stone, M. D., Goodfellow, Rhian Mair, Choy, Ernest Ho Sing ORCID: https://orcid.org/0000-0003-4459-8609, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 and Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X 2012. TNF-like protein 1A/death receptor 3 pathway regulates osteoclastogenesis and is associated with erosive disease in rheumatoid arthritis. Arthritis and Rheumatism 64 (10) , S768-S768.

Greenhill, Claire J., Jones, Gareth Wyn, Nowell, Mari Ann, Moideen, Abdul Nazeer, Rosas, Marcela ORCID: https://orcid.org/0000-0002-9442-9638, Taylor, Philip Russel ORCID: https://orcid.org/0000-0003-0163-1421, Humphreys, Ian R. ORCID: https://orcid.org/0000-0002-9512-5337, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2012. Cross-talk between IL-10 and the inflammasome regulates bone erosions during rheumatoid arthritis [Abstract]. Immunology 137 , pp. 43-44.

Collins, Fraser, Stone, M., Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 and Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X 2012. Death receptor 3 and tl1a: A regulatory pathway of bone turnover and target for osteoporosis therapy? [Abstract]. Osteoporosis International 23 , S528-S528.

Bonnet, Cleo, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Harvey, Ann, Gilbert, Sophie Jane, Moideen, Abdul Nazeer, Nowell, Mari Ann and Mason, Deborah Jane ORCID: https://orcid.org/0000-0002-8666-6094 2012. Intra-articular AMPA/kainate glutamate receptor antagonists alleviate inflammation, pain and pathology in rat antigen induced arthritis [Abstract]. Osteoporosis International 23 , S527-S527.

Moideen, Abdul Nazeer, Evans, Laura, Osgood, Louise Emma, Williams, Anwen ORCID: https://orcid.org/0000-0001-6118-020X, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 and Nowell, Mari Ann 2012. Nicotinamide adenine dinucleotide (NAD plus) biosynthesis enzymes in rheumatoid arthritis [Abstract]. Rhuematology 51 (s3) , p. 142. 10.1093/rheumatology/kes108

Collins, Fraser, Stone, Michael D., Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 and Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X 2012. Death receptor 3 and Tl1a: A driving force in osteoclast differentiation and potential target for rheumatoid arthritis therapy [Abstract]. Rheumatology 51 (s3) , p. 140. 10.1093/rheumatology/kes108

Greenhill, Claire, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Jones, Gareth Wyn, Nowell, Mari Ann, Moideen, Abdul Nazeer, Rosas, Marcela ORCID: https://orcid.org/0000-0002-9442-9638, Taylor, Philip Russel ORCID: https://orcid.org/0000-0003-0163-1421, Humphreys, Ian R. ORCID: https://orcid.org/0000-0002-9512-5337 and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2012. The regulation of arthritic bone erosions by il-10 [Abstract]. Rhuematology 51 , p. 48. 10.1093/rheumatology/kes117

Jones, Gareth Wyn, Greenhill, Claire J., Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Nowell, Mari Ann, Jenkins, Brian J. and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2012. Interleukin-27 receptor-deficient mice develop exacerbated inflammatory arthritis associated with heightened T- and B-cell responses [Abstract]. Rhuematology 51 (s3) , pp. 43-44. 10.1093/rheumatology/kes117

Nowell, Mari Ann, Evans, Laura Catherine and Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X 2012. PBEF/NAMPT/visfatin: a promising drug target for treating rheumatoid arthritis? Future Medicinal Chemistry 4 (6) , pp. 751-769. 10.4155/fmc.12.34

Jones, Gareth Wyn, Greenhill, C. J., Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Nowell, Mari Ann, Jenkins, B. J. and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2011. Interleukin-27 receptor-deficient mice develop exacerbated inflammatory arthritis associated with heightened T- and B-cell responses [Abstract]. Immunology 135 (S1) , p. 158. 10.1111/j.1365-2567.2011.03534.x

Greenhill, Claire J., Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Jones, Gareth Wyn, Nowell, Mari Ann, Rosas, Marcela ORCID: https://orcid.org/0000-0002-9442-9638, Taylor, Philip Russel ORCID: https://orcid.org/0000-0003-0163-1421, Humphreys, Ian R. ORCID: https://orcid.org/0000-0002-9512-5337 and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2011. The regulation of arthritic bone erosions by IL-10 [Abstract]. Immunology 135 (s1) , p. 158. 10.1111/j.1365-2567.2011.03534.x

Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Newton, Zarabeth, Collins, Fraser, Hayward, Olivia, Perks, William Victor, Singh, Ravinder, Twohig, Jason Peter and Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X 2011. Control of early cartilage destruction in inflammatory arthritis by death receptor 3 [Abstract]. Immunology 135 (s1) , p. 153. 10.1111/j.1365-2567.2011.03534.x

Bonnet, C. S., Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Moideen, A. N., Nowell, Mari Ann and Mason, Deborah Jane 2011. Intra-articular AMPA/kainate glutamate receptor antagonists alleviate inflammation, pain and pathology in rat antigen induced arthritis [Abstract]. International Journal of Experimental Pathology 92 (6) , A14-A14. 10.1111/j.1365-2613.2011.00780.x

Jones, Gareth Wyn, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Nowell, Mari Ann, Jenkins, Brian J. and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2011. Interleukin-27 receptor-deficient mice develop exacerbated inflammatory arthritis associated with heightened T- and B- cell responses [Abstract]. Arthritis and Rheumatism 63 (s10) , S978-S978. 10.1002/art.33310

Paringe, Vishal, Bloom, A. C., Choy, Ernest Ho Sing ORCID: https://orcid.org/0000-0003-4459-8609, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X 2011. Compromised expression of the complement membrane inhibitor CD59a propagates age-related joint degeneration in mice [Poster Abstract]. Arthritis and Rheumatism 63 (s10) , S947-S947. 10.1002/art.33310

Smale, Shaun, Carty, Sara Madelaine, Goodfellow, Rhian Mair, Choy, Ernest Ho-Sing ORCID: https://orcid.org/0000-0003-4459-8609, Rose-John, Stefan, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 and Williams, Anwen SIan ORCID: https://orcid.org/0000-0001-6118-020X 2011. Inhibiting IL-6 trans-signalling with soluble gp130Fc potently reduces the incidence and severity of collagen-induced experimental arthritis [Abstract]. Arthritis and Rheumatism 63 (s10) , S446-S447.

Evans, Laura Catherine, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Hayes, Anthony Joseph, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 and Nowell, Mari Ann 2011. Suppression of leukocyte infiltration and cartilage degradation by selective inhibition of pre-B cell colony-enhancing factor/visfatin/nicotinamide phosphoribosyltransferase: Apo866-mediated therapy in human fibroblasts and murine collagen-induced arthritis. Arthritis and Rheumatism 63 (7) , pp. 1866-1877. 10.1002/art.30338

Evans, Alison, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Hayes, Anthony Joseph and Nowell, Mari Ann 2011. Investigating the role of PBEF on cartilage integrity [Abstract]. International Journal of Experimental Pathology 92 (3) , A33-A34. 10.1111/j.1365-2613.2010.00759.x

Bloom, Anja Constanze, Collins, Fraser, Evans, Bronwen Alice James ORCID: https://orcid.org/0000-0002-3082-1008, Aeschlimann, Daniel P. ORCID: https://orcid.org/0000-0003-0930-7706, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X 2011. CD59 an unexpected protective role in bone [Abstract]. Bone 48 , S161-S162.

Jones, Gareth Wyn, Stumhofer, Jason S., Foster, Tom, Twohig, Jason Peter, Hertzog, Paul, Topley, Nicholas, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Hunter, Christopher A., Jenkins, Brendan J., Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2011. Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation. The FASEB Journal 25 (1) , pp. 409-419. 10.1096/fj.10-166843

Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Collins, Fraser, Newton, Zarabeth, Goodfellow, Rhian Mair, Rajak, Rushda, Calder, Claudia Jean and Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 2010. Death Receptor 3 orchestrates erosive pathology in inflammatory arthritis [Poster Abstract]. Immunology 131 (s1) , p. 53. 10.1111/j.1365-2567.2010.03390.x

Jones, Gareth Wyn, Stumhofer, J. S., Foster, T., Twohig, Jason Peter, Hertzog, P., Topley, Nicholas, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Hunter, Catherine, Jenkins, Brian J., Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 and Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 2010. Differential responsiveness of naive and activated T cells to TL1A that affect Th17 generation, maintenance and proliferation [Abstract]. Immunology 131 (s1) , p. 102. 10.1111/j.1365-2567.2010.03390.x

Lissilaa, Rami, Buatois, Vanessa, Magistrelli, Giovanni, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Jones, Gareth Wyn, Herren, Suzanne, Shang, Limin, Malinge, Pauline, Guilhot, Florence, Chatel, Laurence, Hatterer, Eric, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711, Kosco-Vilbois, Marie H. and Ferlin, Walter G. 2010. Although IL-6 trans-signaling is sufficient to drive local immune responses, classical IL-6 signaling is obligate for the induction of T cell-mediated autoimmunity. The Journal of Immunology 185 (9) , pp. 5512-5521. 10.4049/jimmunol.1002015

Jones, Gareth Wyn, McLoughlin, Rachel Mary, Hammond, Victoria Jayne, Parker, Clare Rhian, Williams, John, Malhotra, Raj, Scheller, Jurgen, Williams, Anwen ORCID: https://orcid.org/0000-0001-6118-020X, Rose-John, Stefan, Topley, Nicholas and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2010. Loss of CD4+ T Cell IL-6R expression during inflammation underlines a role for IL-6 trans signaling in the local maintenance of Th17 cells. The Journal of Immunology 184 (4) , pp. 2130-2139. 10.4049/jimmunol.0901528

Jones, Gareth Wyn, McLoughlin, R. M., Hammond, Victoria Jayne, Parker, Clare R., Williams, John D., Malhotra, R., Scheller, J., Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Rose-John, Stefan, Topley, Nicholas and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2010. Loss of CD4(+) T cell IL-6R expression during inflammation underlines a role for IL-6 trans signaling in the local maintenance of Th17 cells. Journal of Immunology 184 (4) , pp. 2130-2139.

Page, Charlotte E., Smale, Shaun, Carty, Sara Madelaine, Amos, Nick, Lauder, Sarah Nicol, Goodfellow, Rhian Mair, Richards, Peter James, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711, Topley, Nicholas and Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X 2010. Interferon-γ inhibits interleukin-1β-induced matrix metalloproteinase production by synovial fibroblasts and protects articular cartilage in early arthritis. Arthritis Research & Therapy 12 (2) , R49. 10.1186/ar2960

Richards, Hannah Catharine, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Jones, Emma, Hindley, James Phillip, Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567, Simon, Anna Katharina and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 2010. Novel role of regulatory T cells in limiting early neutrophil responses in skin. Immunology 131 (4) , pp. 583-592. 10.1111/j.1365-2567.2010.03333.x

Page, Charlotte E., Smale, Shaun, Carty, Sara Madelaine, Amos, Nick, Lauder, Sarah Nicol, Goodfellow, Rhian Mair, Richards, Peter J., Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711, Topley, Nicholas and Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X 2010. Interferon-gamma inhibits interleukin-1 beta-induced matrix metalloproteinase production by synovial fibroblasts and protects articular cartilage in early arthritis. Arthritis Research and Therapy 12 (2) , R49.

Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Bull, Melanie, Newton, Zarabeth, Calder, Claudia Jane, Twohig, Jason Peter, Elford, Carole, Evans, Bronwen Alice James ORCID: https://orcid.org/0000-0002-3082-1008, Al-Shamkhani, A. and Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 2009. A functional role for death receptor-3 in arthritis [Abstract]. Cytokine 48 (1-2) , p. 134. 10.1016/j.cyto.2009.07.568

Newton, Zarabeth, Bull, Melanie, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 and Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X 2009. The role of dr3/tl1a in cartilage depletion caused by inflammatory arthritis [Abstract]. Rhuematology 48 (s1) , I30-I30. 10.1093/rheumatology/kep713

Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Bull, Melanie, Newton, Zarabeth, Calder, Claudia Jane, Twohig, Jason Peter, Elford, Carole, Evans, Bronwen Alice James ORCID: https://orcid.org/0000-0002-3082-1008, Al-Shamkhani, A. and Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 2009. Functional role of dr3 in inflammatory arthritis: A novel target for therapy? [Abstract]. Rheumatology 48 (s1) , I8-I8. 10.1093/rheumatology/kep704

Nowell, Mari Ann, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Carty, Sara Madelaine, Scheller, Jurgen, Hayes, Anthony Joseph, Jones, Gareth Wyn, Richards, Peter James, Slinn, Simon James, Ernst, Matthias, Jenkins, Brendan J., Topley, Nicholas, Rose-John, Stephen and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2009. Therapeutic targeting of IL-6 trans signaling counteracts STAT3 control of experimental inflammatory arthritis. Journal of Immunology 182 (1) , pp. 613-622.

Jones, Gareth Wyn, Stumhofer, J. S., Newton, Zarabeth, Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004, Ernst, M., Topley, Nicholas, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Hunter, Catherine, Jenkins, Brian J., Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2008. TL1A/TNFSF15 promotes a STAT1-mediated suppression of IL-17-secreting T-helper cells [Abstract]. Immunology 125 (s1) , p. 62. 10.1111/j.1365-2567.2008.02974.x

Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Bull, Melanie, Newton, Zarabeth, Calder, Claudia Jane, Twohig, Jason Peter, Elford, Carole, Evans, Bronwen Alice James ORCID: https://orcid.org/0000-0002-3082-1008, Rowley, T. F., Slebioda, T. J., Taraban, V. Y., Al-Shamkhani, A. and Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 2008. The role of death receptor 3 in inflammatory arthritis [Abstract]. Immunology 125 , p. 34. 10.1111/j.1365-2567.2008.02974.x

Bull, Melanie Jane, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Newton, Zarabeth, Calder, Claudia, Twohig, Jason Peter, Elford, Carole, Evans, Bronwen Alice James ORCID: https://orcid.org/0000-0002-3082-1008, Rowley, T. F., Slebioda, T. J., Taraban, V. Y., Al-Shamkhani, A. and Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 2008. The Death Receptor 3-TNF-like protein 1A pathway drives adverse bone pathology in inflammatory arthritis. Journal of Experimental Medicine 205 (11) , pp. 2457-2464. 10.1084/jem.20072378

Rabe, B., Chalaris, A., Adams, N., Paliga, K., Lange, H., Laskay, T., Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153, Waetzig, G. H., Seegert, D., Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711, Sina, C., Rose-John, Stefan and Schelle, J. 2008. The role of IL6-transsignaling in acute and chronic inflammation [Abstract]. Cytokine 43 (3) , p. 244. 10.1016/j.cyto.2008.07.073

Hams, Emily ORCID: https://orcid.org/0000-0002-9745-3246, Colmont, Chantal Sophie, Dioszeghy, Vincent, Hammond, Victoria Jayne, Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Tanaka, Minoru, Miyajima, Atsushi, Taylor, Philip Russel ORCID: https://orcid.org/0000-0003-0163-1421, Topley, Nicholas and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2008. Oncostatin M receptor-β signaling limits monocytic cell recruitment in acute inflammation. Journal of Immunology 181 (3) , pp. 2174-2180.

Hams, Emily, Colmont, Chantal S., Dioszeghy, Vincent, Hammond, Victoria Jayne, Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Tanaka, Minoru, Miyajima, Atsushi, Taylor, Philip Russel ORCID: https://orcid.org/0000-0003-0163-1421, Topley, Nicholas and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2008. Oncostatin M receptor-beta signaling limits monocytic cell recruitment in acute inflammation. Journal of Immunology 181 (3) , pp. 2174-2180.

Jones, Gareth Wyn, Newton, Zarabeth, Nowell, Mari Ann, Jenkins, B. J., Ernst, M., Topley, Nicholas, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2008. TL1A negatively regulates development of T helper 17 cells [Abstract]. Rheumatology 47 (S2) , II20-II20. 10.1093/rheumatology/kem509

Page, Charlotte E., Smale, Shaun, Lauder, Sarah Nicol, Carty, Sara Madelaine, Goodfellow, Rhian Mair, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711, Topley, Nicholas and Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X 2008. Ifn gamma protects articular cartilage against IL-1 induced tissue injury in arthritis. C Page, S Smale, S Lauder, S Carty, R Goodfellow, S Jones, N Topley & A Williams. School of medicine, Cardiff University, Cardiff, CF14 4XN [Poster Abstract]. Rhuematology 47 (s2) , II177-II177. 10.1093/rheumatology/kem534

Nowell, Mari Ann and Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X 2008. Selective inhibition of PBEF activity with a small molecule inhibitor, APO866 ameliorates collagen-induced arthritis [Abstract]. Rheumatology 47 , II58-II59.

Smale, Shaun, Amos, Nick, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 and Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X 2008. Local activation of STAT3 but not STAT1 during collagen induced arthritis. Correlation with local and systemic cytokine activity [Poster Abstract]. Rheumatology 47 (s2) , II53-II53. 10.1093/rheumatology/kem514

Rabe, Bjorn, Chalaris, Athena, May, Ulrike, Waetzig, Georg H., Seegert, Dirk, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711, Rose-John, Stefan and Scheller, Jurgen 2008. Transgenic blockade of interleukin 6 transsignaling abrogates inflammation. Blood 111 (3) , pp. 1021-1028. 10.1182/blood-2007-07-102137

Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711, Jones, Gareth Wyn, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X and Nowell, Mari Ann 2008. Appreciating the balance between classical interleukin (IL)-6 receptor signaling and IL-6 trans-signaling: implications for arthritis progression. Immunology Endocrine & Metabolic Agents in Medicinal Chemistry 8 (3) , pp. 235-246.

Hepburn, Natalie Jayne, Chamberlain-Banoub, Jayne L., Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Harris, Claire Louise 2008. Prevention of experimental autoimmune myasthenia gravis by rat Crry-Ig: a model agent for long-term complement inhibition in vivo. Molecular Immunology 45 (2) , pp. 395-405. 10.1016/j.molimm.2007.06.144

Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X and Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X 2008. Stopping the traffic: A route to arthritis therapy. European Journal of Immunology 38 (10) , pp. 2650-2653. 10.1002/eji.200838786

Rabe, B., Chalaris, Athena, May, Ulrike, Paliga, Krzysztof, Lange, Hans, Laskay, Tamas, Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153, Waetzig, Georg H., Seegert, Dirk, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711, Rose-John, Stefan and Scheller, J. 2007. IL6/sIL6R-transsignaling controls innate and aquired immunity [Abstract]. Cytokine 39 (1) , p. 34. 10.1016/j.cyto.2007.07.129

Jones, Gareth Wyn, Newton, Zarabeth, Jenkins, B. J., Ernst, M., Topley, Nicholas, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2007. TL1A counteracts the IL-6 control of the STAT3-mediated development of T helper 17 cells [Abstract]. Cytokine 39 (1) , pp. 18-19.

Hams, Emily, Dioszechy, Vincent, Colmont, Chantal Sophie, Hammond, Victoria Jayne, Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Tanaka, Minoru, Miyajima, Atsushi, Taylor, Philip Russel ORCID: https://orcid.org/0000-0003-0163-1421, Topley, Nicholas and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2007. Oncostatin M receptor signalling regulates monocytic cell trafficking during acute inflammation [Abstract]. Cytokine 39 (1) , p. 14. 10.1016/j.cyto.2007.07.053

Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Richards, Peter James, Thomas, Eleri, Carty, Sara Madelaine, Nowell, Mari Ann, Goodfellow, Rhian Mair, Dent, Colin Michael, Williams, Bryan Davies, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 and Topley, Nicholas 2007. Interferon-γ protects against the development of structural damage in experimental arthritis by regulating polymorphonuclear neutrophil influx into diseased joints. Arthritis & Rheumatism 56 (7) , pp. 2244-2254. 10.1002/art.22732

Page, Charlotte E., Smale, Shaun, Lauder, Sarah Nicol, Carty, Sara Madelaine and Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X 2007. Interferon gamma decreases interleukin 1 beta-mediated cartilage loss in rheumatoid arthritis [Abstract]. Rheumatology 46 , I45-I46.

Carty, Sara Madelaine, Nowell, Mari Ann, Lauder, Sarah Nicol, Goodfellow, Rhian Mair, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711, Williams, B. D. and Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X 2007. Combination therapy with etanercept and sgp130 for rheumatoid arthritis is more effective than monotherapy [Abstract]. Rheumatology 46 (s1) , I18-I18. 10.1093/rheumatology/kem1007

Hepburn, Natalie Jayne, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Harris, Claire Louise 2007. In Vivo Characterization and Therapeutic Efficacy of a C5-specific Inhibitor from the Soft Tick Ornithodoros moubata. J Biol Chem 282 , pp. 8292-8299. 10.1074/jbc.M609858200

Hepburn, Natalie J., Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Chamberlain, Jayne C., Hamer, Joseph, Nunn, M. A., Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Harris, Claire Louise 2007. In vivo characterisation and therapeutic efficacy of a C5-specific inhibitor [Abstract]. Molecular Immunology 44 (1-3) , p. 183. 10.1016/j.molimm.2006.07.087

Carty, Sara Madelaine, Nowell, Mari Ann, Goodfellow, Rhian Mair, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711, Williams, B. D. and Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X 2006. TINFa and IL-6/slL-6R interactions regulate the magnitude and the phenotype of synovial Leucocyte infiltration in rheumatoid arthritis [Abstract]. Arthritis and Rheumatism 54 (9) , S597-S597.

Nowell, Mari Ann, Richards, Peter James, Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153, Ognjanovic, Simona, Topley, Nicholas, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Bryant-Greenwood, Gillian and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2006. Regulation of pre-B cell colony-enhancing factor by STAT-3-dependent interleukin-6 trans-signaling: implications in the pathogenesis of rheumatoid arthritis. Arthritis & Rheumatism 54 (7) , pp. 2084-2095. 10.1002/art.21942

Richards, Peter James, Nowell, Mari Ann, Horiuchi, Sankichi, McLoughlin, Rachel Mary, Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153, Grau, Sandra, Yamamoto, Naoki, Ehrmann, Michael ORCID: https://orcid.org/0000-0002-1927-260X, Rose-John, Stefan, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Topley, Nicholas and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2006. Functional characterization of a soluble gp130 isoform and its therapeutic capacity in an experimental model of inflammatory arthritis. Arthritis & Rheumatism 54 (5) , pp. 1662-1672. 10.1002/art.21818

Grau, Sandra, Richards, Peter J., Kerr, Briedgeen, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Junker, Uwe, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711, Clausen, Tim and Ehrmann, Michael ORCID: https://orcid.org/0000-0002-1927-260X 2006. The role of human HtrA1 in arthritic disease. The Journal of Biological Chemistry 281 (10) , pp. 6124-6129. 10.1074/jbc.M500361200

Flood, S. J., Parri, R., Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Duance, Victor Colin and Mason, Deborah Jane 2006. Ionotropic glutamate receptors are functional in human fibroblast-like synoviocytes and modulate IL-6 and MMP-2 expression [Abstract]. Bone 38 (3) , S36-S36.

Richards, H. E., Simon, A. K., Jones, E., Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Screaton, G. R. and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004 2005. Inhibition of innate immune responses to tumours by CD4+CD25+ regulatory T cells [Abstract]. Immunology 116 (s1) , p. 36. 10.1111/j.1365-2567.2005.02287.x

McLoughlin, Rachel Mary, Jenkins, Brendan J., Grail, Dianne, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153, Parker, Clare R., Ernst, Matthias, Topley, Nicholas and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2005. IL-6 trans-signaling via STAT3 directs T cell infiltration in acute inflammation. Proceedings of the National Academy of Sciences of the United States of America (PNAS) ISSN 1091-6490 102 (27) , pp. 9589-9594. 10.1073/pnas.0501794102

Redman, S., Haughton, Laura, Dowthwaite, G., Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X and Archer, Charles William 2005. The effect of Notch signal inhibition on osteoarthritic micromass cultures [Abstract]. International Journal of Experimental Pathology 86 (3) , A48-A48.

Carty, S. M., Nowell, Mari Ann, Goodfellow, Rhian Mair, Topley, Nicholas, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711, Williams, B. D. and Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X 2005. Interleukin 6 (IL-6) signalling in rheumatoid arthritis. Rheumatology 44 , I38-I38.

Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Mizuno, Masashi, Richards, Peter James, Holt, Dewi Stanley and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2004. Deletion of the gene encoding CD59a in mice increases disease severity in a murine model of rheumatoid arthritis. Arthritis & Rheumatism 50 (9) , pp. 3035-3044. 10.1002/art.20478

Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Fraser, D. A., Harris, Claire Louise and Mizuno, Masashi 2003. Generation of a recombinant, membrane-targeted form of the complement regulator CD59: activity in vitro and in vivo. The Journal of Biological Chemistry 278 (49) , pp. 48921-48927. 10.1074/jbc.M302598200

Harris, Claire Louise, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Goodfellow, Ian, Evans, David J., Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2003. Generation of anti-complement 'prodrugs': cleavable reagents for specific delivery of complement regulators to disease sites. The Journal of Biological Chemistry 278 (38) , pp. 36068-36076. 10.1074/jbc.M306351200

Nowell, Mari Ann, Richards, Peter James, Horiuchi, Sankichi, Yamamoto, Naoki, Rose-John, Stefan, Topley, Nicholas, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X and Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 2003. Soluble IL-6 receptor governs IL-6 activity in experimental arthritis: blockade of arthritis severity by soluble glycoprotein 130. The Journal of Immunology 171 (6) , pp. 3202-3209.

McLoughlin, Rachel Mary, Witowski, Janusz, Robson, Rachel L., Wilkinson, Thomas S., Hurst, Suzanne Maria, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Williams, John David, Rose-John, Stefan, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 and Topley, Nicholas 2003. Interplay between IFN-gamma and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation. The Journal of Clinical Investigation 112 (4) , pp. 598-607. 10.1172/JCI200317129

Davies, Janet R., Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Akhtar, Saeed and Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 2001. Appearance of a proteoglycan layer on the articular surface in murine antigen induced arthritis - Is this an accumulation of superficial zone proteoglycan (SZP)? [Poster Abstract]. International Journal of Experimental Pathology 82 (6) , A5. 10.1046/j.1365-2613.2001.82_6am.x

Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Jones, S. G., Goodfellow, Rhian Mair, Amos, Nick and Williams, B. D. 1999. Interleukin-1β (IL-1β) inhibition: a possible mechanism for the anti-inflammatory potency of liposomally conjugated methotrexate formulations in arthritis. British Journal of Pharmacology 128 (1) , pp. 234-240. 10.1038/sj.bjp.0702776