Browse by Current Cardiff authors

Woods, Emma L., Grigorieva, Irina V., Midgley, Adam C., Brown, Charlotte V.M., Lu, Yueh-an, Phillips, Aled O. ORCID: https://orcid.org/0000-0001-9744-7113, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978 and Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 2021. CD147 mediates the CD44s-dependent differentiation of myofibroblasts driven by transforming growth factor-β1. Journal of Biological Chemistry 297 (3) , 100987. 10.1016/j.jbc.2021.100987

Holmes, Jennifer, Donovan, Kieron, Geen, John, Williams, John and Phillips, Aled O. ORCID: https://orcid.org/0000-0001-9744-7113 2021. Acute kidney injury demographics and outcomes: changes following introduction of electronic acute kidney injury alerts—an analysis of a national dataset. Nephrology Dialysis Transplantation 36 (8) , pp. 1433-1439. 10.1093/ndt/gfaa071

Khalid, Sami A., Musa, Abdelrahman, Saeed, Amal, Elkhair Ali Ali, Nour, Abugroun, Elsir A., Mohamed, Ghalib, Elnima, Elamin I., Alkarib, Suaad Y., Gbir Agib, Elsadig, Phillips, Glyn O. ORCID: https://orcid.org/0000-0001-9744-7113 and Phillips, Aled O. ORCID: https://orcid.org/0000-0001-9744-7113 2021. Gum Arabic in renal disease (GARDS Study): Clinical evidence of dietary supplementation impact on progression of renal dysfunction. Journal of Functional Foods 82 , 104515. 10.1016/j.jff.2021.104515

Jones, Aled, Holmes, Jennifer, Stephens, Michael, Geen, John, Williams, John, Donovan, Kieron and Phillips, Aled O. ORCID: https://orcid.org/0000-0001-9744-7113 2021. Using electronic AKI alerts to define the epidemiology of acute kidney injury in renal transplants. Journal of Nephrology 34 , pp. 829-838. 10.1007/s40620-020-00869-z

Holmes, Jennifer, Geen, John, Williams, John D and Phillips, Aled O ORCID: https://orcid.org/0000-0001-9744-7113 2020. Recurrent acute kidney injury: predictors and impact in a large population-based cohort. Nephrology Dialysis Transplantation 35 (8) , pp. 1361-1369. 10.1093/ndt/gfz155

Midgley, Adam C., Woods, Emma, Jenkins, Robert ORCID: https://orcid.org/0000-0001-8500-9044, Brown, Charlotte, Khalid, Usman, Chavez, Rafael, Hascall, Vincent, Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496, Phillips, Aled O. ORCID: https://orcid.org/0000-0001-9744-7113 and Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978 2020. Hyaluronidase-2 regulates RhoA signalling, myofibroblast contractility and other key pro-fibrotic myofibroblast functions. American Journal of Pathology 190 (6) , pp. 1236-1255. 10.1016/j.ajpath.2020.02.012

Foxwell, David A, Pradhan, Sara, Zouwail, Soha, Rainer, Timothy H ORCID: https://orcid.org/0000-0003-3355-3237 and Phillips, Aled O ORCID: https://orcid.org/0000-0001-9744-7113 2020. Epidemiology of emergency department acute kidney injury. Nephrology 25 (6) , pp. 457-466. 10.1111/nep.13672

Gubb, Samuel, Holmes, Jennifer, Smith, Graham, Geen, John, Williams, John, Donovan, Kieron and Phillips, Aled O. ORCID: https://orcid.org/0000-0001-9744-7113 2020. Acute kidney injury in children based on electronic alerts. Journal of Pediatrics 220 , 4-6.e1. 10.1016/j.jpeds.2019.11.019

Allen, Lowri A, Pyart, Rhodri D, Holmes, Jennifer, Donovan, Kieron L, Anderson, Richard A and Phillips, Aled O ORCID: https://orcid.org/0000-0001-9744-7113 2019. Cardiovascular and renal outcomes following percutaneous coronary intervention in a population with renal disease: a case-control study. QJM: An International Journal of Medicine 112 (9) , pp. 669-674. 10.1093/qjmed/hcz130

Phillips, Dafydd ORCID: https://orcid.org/0000-0001-9744-7113, Holmes, Jennifer, Davies, Richard, Geen, John, Williams, John D and Phillips, Aled O ORCID: https://orcid.org/0000-0001-9744-7113 2018. The influence of socioeconomic status on presentation and outcome of acute kidney injury. QJM: An International Journal of Medicine 111 (12) , pp. 849-857. 10.1093/qjmed/hcy180

Wang, Junqiao, Nie, Shaoping, Chen, Shuping, Phillips, Aled O. ORCID: https://orcid.org/0000-0001-9744-7113, Phillips, Glyn O. ORCID: https://orcid.org/0000-0001-9744-7113, Li, Yajing, Xie, Mingyong and Cui, Steve W. 2018. Structural characterization of an α-1, 6-linked galactomannan from natural Cordyceps 2 sinensis. Food Hydrocolloids 78 , pp. 77-91. 10.1016/j.foodhyd.2017.07.024

Huang, Danfei, Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978, Nie, Shao-Ping, Midgley, Adam C., Wang, Junqiao, Cui, Steve W., Xie, Mingyong, Phillips, Glyn O. ORCID: https://orcid.org/0000-0001-9744-7113 and Phillips, Aled O. ORCID: https://orcid.org/0000-0001-9744-7113 2018. Cordyceps Sinensis: anti-fibrotic and inflammatory effects of a cultured polysaccharide extract. Bioactive Carbohydrates and Dietary Fibre 14 , pp. 2-8. 10.1016/j.bcdf.2017.07.012

Midgley, Adam C., Oltean, Sebastian, Hascall, Vincent, Woods, Emma L., Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496, Phillips, Aled O. ORCID: https://orcid.org/0000-0001-9744-7113 and Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978 2017. Nuclear hyaluronidase 2 drives alternative splicing of CD44 pre-mRNA to determine profibrotic or antifibrotic cell phenotype. Science Signaling 10 (506) , eaao1822. 10.1126/scisignal.aao1822

Holmes, Jennifer, Geen, John, Phillips, Bethan, Williams, John and Phillips, Aled ORCID: https://orcid.org/0000-0001-9744-7113 2017. Community acquired acute kidney injury: findings from a large population cohort. QJM: An International Journal of Medicine 110 (11) , pp. 741-746. 10.1093/qjmed/hcx151

Phillips, Dafydd, Young, Oliver, Holmes, Jennifer, Allen, Lowri, Roberts, Gethin, Geen, John, Williams, John and Phillips, Aled ORCID: https://orcid.org/0000-0001-9744-7113 2017. Seasonal pattern of incidence and outcome of acute kidney injury: A national study of Welsh AKI electronic alerts. International Journal of Clinical Practice 71 (9) , e13000. 10.1111/ijcp.13000

Holmes, Jennifer, Allen, Nicholas, Roberts, Gethin, Geen, John, Williams, John D. and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2017. Acute kidney injury: electronic alerts in primary care - findings from a large population cohort. QJM: An International Journal of Medicine 110 (9) , pp. 577-582. 10.1093/qjmed/hcx080

Holmes, Jennifer, Roberts, Gethin, May, Kate, Tyerman, Kay, Geen, John, Williams, John D. and Phillips, Aled O. ORCID: https://orcid.org/0000-0001-9744-7113 2017. The incidence of pediatric acute kidney injury is increased when identified by a change in a creatinine-based electronic alert. Kidney International 92 (2) , pp. 432-439. 10.1016/j.kint.2017.03.009

Wang, Junqiao, Nie, Shaoping, Cui, Steve W., Wang, Zhijun, Phillips, Aled O. ORCID: https://orcid.org/0000-0001-9744-7113, Phillips, Glyn O., Li, Yajing and Xie, Mingyong 2017. Structural characterization and immunostimulatory activity of a glucan from natural Cordyceps sinensis. Food Hydrocolloids 67 , pp. 139-147. 10.1016/j.foodhyd.2017.01.010

Wang, Junqiao, Nie, Shaoping, Kan, Lijiao, Chen, Haihong, Cui, Steve W., Phillips, Aled O. ORCID: https://orcid.org/0000-0001-9744-7113, Phillips, Glyn O. and Xie, Mingyong 2017. Comparison of structural features and antioxidant activity of polysaccharides from natural and cultured Cordyceps sinensis. Food Science and Biotechnology 26 (1) , 55. 10.1007/s10068-017-0008-3

Holmes, J, Rainer, Timothy ORCID: https://orcid.org/0000-0003-3355-3237, Geen, J, Roberts, G, May, K, Wilson, N, Williams, JD and Phillips, Aled ORCID: https://orcid.org/0000-0001-9744-7113 2016. Acute kidney injury in the era of the AKI E-Alert. Clinical Journal of the American Society of Nephrology 11 10.2215/CJN.05170516

Johnson, Faye, Phillips, Dafydd, Talabani, Bnar, Wonnacott, Alexa ORCID: https://orcid.org/0000-0002-0968-4248, Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978 and Phillips, Aled ORCID: https://orcid.org/0000-0001-9744-7113 2016. The impact of acute kidney injury in diabetes mellitus. Journal of Thrombosis and Haemostatis 21 (6) , pp. 506-511. 10.1111/nep.12649

Midgley, Adam C., Morris, Glyn, Phillips, Aled O. ORCID: https://orcid.org/0000-0001-9744-7113 and Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 2016. 17β‐estradiol ameliorates age‐associated loss of fibroblast function by attenuating IFN‐γ/STAT1‐dependent miR‐7 upregulation. Aging Cell 15 (3) , pp. 531-541. 10.1111/acel.12462

Martin, John, Midgley, Adam, Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978, Woods, Emma, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Phillips, Aled O. ORCID: https://orcid.org/0000-0001-9744-7113 and Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 2016. Tumour necrosis factor-stimulated gene (TSG)-6-mediated interactions with the inter-alpha-inhibitor heavy chain 5 facilitate TGF beta1-dependent fibroblast to myofibroblast differentiation. Journal of Biological Chemistry 291 , pp. 13789-13801. 10.1074/jbc.M115.670521

El-hassan, El-hussein E A, Ghalib, Mohamed B, Ibrahim, Azam I S, Phillips, Bethan and Phillips, Aled ORCID: https://orcid.org/0000-0001-9744-7113 2016. Glomerular disease and acute kidney injury in Sudan: Demographics, histological diagnosis and outcome. South African Medical Journal 106 (7) , pp. 704-708. 10.7196/SAMJ.2016.v106i7.10392

Beltrami, Cristina, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Newbury, Lucy, Corish, Peter, Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 2015. Stabilization of urinary microRNAs by association with exosomes and argonaute 2 protein. Non-Coding RNA 1 (2) , pp. 151-166. 10.3390/ncrna1020151

Roberts, Gareth, Phillips, Dafydd, McCarthy, Rowan, Bolusani, Hemanth, Mizen, Paul, Hassan, Mohamed, Hooper, Rachel, Saddler, Kimberly, Hu, Mo, Lodhi, Sonal, Toynton, Ella, Geen, John, Lodhi, Vikas, Grose, Catherine and Phillips, Aled ORCID: https://orcid.org/0000-0001-9744-7113 2015. Acute kidney injury risk assessment at the hospital front door: what is the best measure of risk? Clinical Kidney Journal 8 (6) , pp. 673-680. 10.1093/ckj/sfv080

Midgley, Adam C., Druggal, Lucy, Jenkins, Robert ORCID: https://orcid.org/0000-0001-8500-9044, Hascall, Vincent, Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496, Phillips, Aled O. ORCID: https://orcid.org/0000-0001-9744-7113 and Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978 2015. Hyaluronan regulates bone morphogenetic protein-7-dependent prevention and reversal of myofibroblast phenotype. Journal of Biological Chemistry 290 (18) , pp. 11218-11234. 10.1074/jbc.M114.625939

Wonnacott, Alexa ORCID: https://orcid.org/0000-0002-0968-4248, Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978, Amphlett, Bethan, Talabani, Bnar and Phillips, Aled ORCID: https://orcid.org/0000-0001-9744-7113 2014. Epidemiology and outcomes in community-acquired versus hospital-acquired AKI. Clinical Journal of the American Society of Nephrology 9 (6) , pp. 1007-1014. 10.2215/CJN.07920713

Talabani, Bnar, Zouwail, Soha, Pyart, Rhodri, Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978, Riley, Stephen and Phillips, Aled ORCID: https://orcid.org/0000-0001-9744-7113 2014. Epidemiology and outcome of community-acquired acute kidney injury. Nephrology 19 (5) , pp. 282-287. 10.1111/nep.12221

Jenkins, Robert H. ORCID: https://orcid.org/0000-0001-8500-9044, Davies, Luke C., Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421, Akiyama, Hideo, Cumbes, Bevan ORCID: https://orcid.org/0000-0001-8529-0040, Beltrami, Cristina, Carrington, Christopher P., Phillips, Aled O. ORCID: https://orcid.org/0000-0001-9744-7113, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 and Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342 2014. miR-192 induces G2/M growth arrest in aristolochic acid nephropathy. American Journal of Pathology 184 (4) , pp. 996-1009. 10.1016/j.ajpath.2013.12.028

Midgley, Adam C., Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Phillips, Aled O. ORCID: https://orcid.org/0000-0001-9744-7113 and Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 2014. MicroRNA-7 inhibition rescues age-associated loss of epidermal growth factor receptor and hyaluronan-dependent differentiation in fibroblasts. Aging Cell 13 (2) , pp. 235-244. 10.1111/acel.12167

Yao, Xiaolin, Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978, Fang, Yapeng, Martin, John, Midgley, Adam, Pan, Ming-Ming, Liu, Bi-Cheng, Cui, Steve W., Phillips, Glyn O. and Phillips, Aled ORCID: https://orcid.org/0000-0001-9744-7113 2014. Cordyceps sinensis: in vitro anti-fibrotic bioactivity of natural and cultured preparations. Food Hydrocolloids 35 , pp. 444-452. 10.1016/j.foodhyd.2013.06.023

Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978, Wonnacott, Alexa ORCID: https://orcid.org/0000-0002-0968-4248, Amphlett, Bethan and Phillips, Aled ORCID: https://orcid.org/0000-0001-9744-7113 2014. How good are we at managing acute kidney injury in hospital? Clinical Kidney Journal 7 (2) , pp. 144-150. 10.1093/ckj/sfu010

Phillips, B M., Milner, S, Zouwail, S, Roberts, G, Cowan, M, Riley, Stephen and Phillips, Aled ORCID: https://orcid.org/0000-0001-9744-7113 2014. Severe hyperkalaemia: demographics and outcome. Clinical Kidney Journal 7 (2) , pp. 127-133. 10.1093/ckj/sft158

Phillips, L.A., Phillips, Bethan, Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978, Russell, J., Zouwail, S., Riley, Stephen and Phillips, Aled ORCID: https://orcid.org/0000-0001-9744-7113 2014. The long-term impact of eGFR reporting on referral patterns. European Journal of Internal Medicine 25 (1) , pp. 97-101. 10.1016/j.ejim.2013.08.001

Jones, Nia J., Chess, James Anthony, Cawley, Scott, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 and Riley, Stephen George 2013. Prevalence of risk factors for foot ulceration in a general haemodialysis population. International Wound Journal 10 (6) , pp. 683-688. 10.1111/j.1742-481X.2012.01044.x

Jones, Ruth K., Hampton, D., O'Sullivan, D. J. and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2013. Diabetes and renal disease: who does what? Clinical Medicine 13 (5) , pp. 460-464. 10.7861/clinmedicine.13-5-460

Pan, M., Zhang, M., Ni, H., Chen, J., Xu, M., Phillips, Aled Owen ORCID: https://orcid.org/0000-0001-9744-7113 and Liu, B. 2013. Inhibition of TGF-β1/Smad signal pathway is involved in the effect of Cordyceps sinensis against renal fibrosis in 5/6 nephrectomy rats. Food and Chemical Toxicology 58 , pp. 487-494. 10.1016/j.fct.2013.04.037

Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978, Martin, John, Luo, Dong Dong, Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2013. Interleukin-1β induces hyaluronan and CD44-dependent cell protrusions that facilitate fibroblast-monocyte binding. American Journal of Pathology 182 (6) , pp. 2223-2240. 10.1016/j.ajpath.2013.02.038

Midgley, Adam Christopher, Rogers, Mathew James, Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 and Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 2013. Transforming growth factor-β1 (TGF-β1)-stimulated fibroblast to myofibroblast differentiation Is mediated by hyaluronan (HA)-facilitated epidermal growth factor receptor (EGFR) and CD44 co-localization in lipid rafts. Journal of Biological Chemistry 288 (21) , pp. 14824-14838. 10.1074/jbc.M113.451336

Phillips, Lowri Angharad, Allen, Nicholas, Phillips, Bethan, Abera, Ammanuel, Diro, Ermias, Riley, Stephen George, Tadesse, Yewondwossen, Williams, John David and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2013. Acute kidney injury risk factor recognition in three teaching hospitals in Ethiopia. South African Medical Journal 103 (6) , pp. 413-418. 10.7196/samj.6424

Nie, Shaoping, Cui, Steve W., Xie, Mingyong, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 and Phillips, Glyn O. 2013. Bioactive polysaccharides from Cordyceps sinensis: Isolation, structure features and bioactivities [Review]. Bioactive Carbohydrates and Dietary Fibre 1 (1) , pp. 38-52. 10.1016/j.bcdf.2012.12.002

Riley, Stephen George, Diro, E., Batchelor, P., Abebe, A., Amsalu, A., Tadesse, T., Williams, John David and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2013. Renal impairment amongst acute hospital admissions in a rural Ethiopian hospital. Nephrology 18 (2) , pp. 92-96. 10.1111/nep.12002

Wonnacott, Alexa ORCID: https://orcid.org/0000-0002-0968-4248, Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978, Roberts, Gareth Wyn, Donovan, Kieron, Riley, Stephen George and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2012. Applying estimated glomerular filtration rate to an ageing population: are we in danger of becoming ageist? European Journal of Internal Medicine 23 (8) , pp. 705-710. 10.1016/j.ejim.2012.08.012

Zhang, Xiao Liang, Bi-Cheng, Liu, Al-Assaf, Saphwan, Phillips, Glyn O. and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2012. Cordyceps sinensis decreases TGF-β1 dependent epithelial to mesenchymal transdifferentiation and attenuates renal fibrosis. Food Hydrocolloids 28 (1) , pp. 200-212. 10.1016/j.foodhyd.2011.12.016

Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044, Martin, John, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 and Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 2012. Transforming growth factor β1 represses proximal tubular cell microRNA-192 expression through decreased hepatocyte nuclear factor DNA binding. Biochemical Journal 443 (2) , pp. 407-416. 10.1042/BJ20111861

Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044, Martin, John, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 and Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 2012. Pleiotropy of microRNA-192 in the kidney. Biochemical Society Transactions 40 (4) , pp. 762-767. 10.1042/BST20120085

Beltrami, Cristina, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 2012. Analysis of urinary microRNAs in chronic kidney disease. Biochemical Society Transactions 40 (4) , pp. 875-879. 10.1042/BST20120090

Zheng, Min, Lv, Lin-Li, Cao, Yu-Han, Zhang, Jian-Dong, Wu, Min, Ma, Kun-Ling, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 and Liu, Bi-Cheng 2012. Urinary mRNA markers of epithelial-mesenchymal transition correlate with progression of diabetic nephropathy. Clinical Endocrinology 76 (5) , pp. 657-664. 10.1111/j.1365-2265.2011.04192.x

Bommayya, Girish, Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978, Krupa, Aleksandra, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 and Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 2011. Tumour necrosis factor-stimulated gene (TSG)-6 controls epithelial–mesenchymal transition of proximal tubular epithelial cells. International Journal of Biochemistry & Cell Biology 43 (12) , pp. 1739-1746. 10.1016/j.biocel.2011.08.009

Michael, Daryn Robert, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113, Krupa, Aleksandra, Martin, John, Redman, James Edward ORCID: https://orcid.org/0000-0001-5492-2869, Altaher, Abdalsamed, Neville, Rachel Dawn, Webber, Jason P. ORCID: https://orcid.org/0000-0003-4772-3014, Kim, Min-Young and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 2011. The human hyaluronan synthase 2 (HAS2) gene and its natural antisense RNA exhibit coordinated expression in the renal proximal tubular epithelial cell. Journal of Biological Chemistry 286 (22) , pp. 19523-19532. 10.1074/jbc.M111.233916

Li, Qing, Liu, Bi-Cheng, Lv, Lin-Li, Ma, Kun-Ling, Zhang, Xiao-Liang and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2011. Monocytes induce proximal tubular epithelial-mesenchymal transition through NF-kappa B dependent upregulation of ICAM-1. Journal of Cellular Biochemistry 112 (6) , pp. 1585-1592. 10.1002/jcb.23074

Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978, Luo, Dong Dong, Simpson, Russell M. L., Martin, John, Wells, Alan, Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2011. Hyaluronan facilitates transforming growth factor-β1-dependent proliferation via CD44 and epidermal growth factor receptor interaction. Journal of Biological Chemistry 286 (20) , pp. 17618-17630. 10.1074/jbc.M111.226563

Martin, John, Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044, Bennagi, Rasha, Krupa, Aleksandra, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 and Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 2011. Post-transcriptional regulation of transforming growth factor beta-1 by microrna-744. PLoS ONE 6 (10) , e25044. 10.1371/journal.pone.0025044

Nie, Shao-Ping, Cui, Steve W., Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113, Xie, Ming-Yong, Phillips, Glyn O., Al-Assaf, Saphwan and Zhang, Xiao-Liang 2011. Elucidation of the structure of a bioactive hydrophilic polysaccharide from Cordyceps sinensis by methylation analysis and NMR spectroscopy. Carbohydrate Polymers 84 (3) , pp. 894-899. 10.1016/j.carbpol.2010.12.033

Asderakis, Argiris, Chaudhry, Aisha, Ilham, Mohamed Adel, Stephens, Michael and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2011. RO-101 Nitric oxide post-perfusion levels differ in DCD and DBD donor transplants [Abstract]. Transplant International 24 (s2) , p. 157. 10.1111/j.1432-2277.2011.01350.x

Tian, Ya-Chung, Hung, Cheng-Chieh, Li, Yi-Jung, Chen, Yung-Chang, Chang, Ming-Yang, Yen, Tzung-Hai, Hsu, Hsiang-Hao, Wu, Mai-Szu, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 and Yang, Chih-Wei 2011. Leptospira santorosai serovar shermani detergent extract induces an increase in fibronectin production through a toll-like receptor 2-mediated pathway. Infection and Immunity 79 (3) , pp. 1134-1142. 10.1128/IAI.01287-09

Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 and Phillips, Glyn O. 2011. Biofunctional behaviour and health benefits of a specific gum arabic. Food Hydrocolloids 25 (2) , pp. 165-169. 10.1016/j.foodhyd.2010.03.012

Khammas, Hassan, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Williams, John David, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113, Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 and Martin, John 2011. Characterisation of the human ADAM15 promoter. Nephron Experimental Nephrology 118 (2) , e27-e38. 10.1159/000320698

Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044, Bennagi, Rasha, Martin, John, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113, Redman, James Edward ORCID: https://orcid.org/0000-0001-5492-2869 and Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 2010. A conserved stem loop motif in the 5'Untranslated Region regulates transforming growth factor-β1 translation. PLoS One 5 (8) , e12283. 10.1371/journal.pone.0012283

Simpson, Russell M. L., Wells, Alan, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820, Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2010. Aging fibroblasts resist phenotypic maturation because of impaired hyaluronan-dependent CD44/epidermal growth factor receptor signaling. American Journal of Pathology 176 (3) , pp. 1215-1228. 10.2353/ajpath.2010.090802

Krupa, Aleksandra, Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044, Luo, Dong Dong, Lewis, Aled G., Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 and Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 2010. Loss of microRNA-192 promotes fibrogenesis in diabetic nephropathy. Journal of the American Society of Nephrology 21 (3) , pp. 438-447. 10.1681/ASN.2009050530

Luo, Dong Dong, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 and Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 2010. Bone morphogenetic protein-7 inhibits proximal tubular epithelial cell smad3 signaling via increased SnoN expression. American Journal of Pathology 176 (3) , pp. 1139-1147. 10.2353/ajpath.2010.090459

Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978, Don, K, Shah, Nilesh, Donovan, Kieron, Riley, Stephen George and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2010. Impact of chronic kidney disease management in primary care. QJM 104 (1) , pp. 27-34. 10.1093/qjmed/hcq151

Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 and Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 2010. BMP-7 stops TGF-β in peritoneal fibrosis. Nephrology Dialysis Transplantation 25 (4) , pp. 1036-1038. 10.1093/ndt/gfq032

Simpson, Russell M. L., Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820, Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2009. Age-related changes in pericellular hyaluronan organization leads to impaired dermal fibroblast to myofibroblast differentiation. American Journal of Pathology 175 (5) , pp. 1915-1928. 10.2353/ajpath.2009.090045

Webber, Jason P. ORCID: https://orcid.org/0000-0003-4772-3014, Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044, Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 and Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 2009. Modulation of TGFβ1-dependent myofibroblast differentiation by hyaluronan. American Journal of Pathology 175 (1) , pp. 148-160. 10.2353/ajpath.2009.080837

Webber, Jason P. ORCID: https://orcid.org/0000-0003-4772-3014, Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978, Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2009. Hyaluronan orchestrates transforming growth factor-β1-dependent maintenance of myofibroblast phenotype. Journal of Biological Chemistry 284 (14) , pp. 9083-9092. 10.1074/jbc.M806989200

Simpson, Russell M.L., Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Thomas, David ORCID: https://orcid.org/0000-0001-7319-5820, Webber, J. P., Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978, Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2009. Age related changes in pericellular hyaluronan leads to impaired dermal fibroblast to myofibroblast differentiation. International Journal of Experimental Pathology 90 (2) , A128-A129.

Luo, Dong Dong, Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 and Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 2009. Interleukin-1 beta regulates proximal tubular cell transforming growth factor beta-1 signalling. Nephrology Dialysis Transplantation 24 (9) , pp. 2655-2665. 10.1093/ndt/gfp208

Glover, David A., Ushida, Kazunari, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 and Riley, Stephen George 2009. Acacia(sen) SUPERGUM™ (gum arabic): an evaluation of potential health benefits in human subjects. Food Hydrocolloids 23 (8) , pp. 2410-2415. 10.1016/j.foodhyd.2009.06.020

Phillips, L. A., Donovan, Kieron and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2009. Renal quality outcomes framework and eGFR: impact on secondary care. QJM 102 (6) , pp. 415-423. 10.1093/qjmed/hcp030

Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820, Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Enoch, Stuart, Martin, John, Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2008. Hyaluronan facilitates transforming growth factor-β1-mediated fibroblast proliferation. Journal of Biological Chemistry 283 (10) , pp. 6530-6545. 10.1074/jbc.M704819200

Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342, Phillips, Aled Owen ORCID: https://orcid.org/0000-0001-9744-7113, Zhang, Xiao Liang, van Roeyen, C. R., Muehlenberg, P., En-Nia, A. and Mertens, P. R. 2008. Y-box protein-1 controls transforming growth factor-β1 translation in proximal tubular cells. Kidney International 73 (6) , pp. 724-732. 10.1038/sj.ki.5002719

Lewis, Aled G., Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496, Manley, Paul, Craig, Kathrine Jane, de la Motte, Carol, Hascall, Vincent and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2008. Diabetic nephropathy, inflammation, hyaluronan and interstitial fibrosis. Histology and Histopathology 23 (6) , pp. 731-739.

Liu, B. C., Li, M. X., Zhang, J. D., Liu, X. C., Zhang, X. L. and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2008. Inhibition of integrin-linked kinase via a siRNA expression plasmid attenuates connective tissue growth factor-induced human proximal tubular epithelial cells to mesenchymal transition. American Journal of Nephrology 28 (1) , pp. 143-151. 10.1159/000110019

Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978, Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 and Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996 2008. Hyaluronan facilitates TGF beta 1 mediated myofibroblastic differentiation [Abstract]. Wound Repair and Regeneration 16 (2) , A12. 10.1111/j.1524-475X.2008.00371.x

Chang, Chiz-Tzung, Hung, Cheng-Chieh, Chen, Yung-Chang, Yen, Tzung-Hai, Wu, Mai-Szu, Yang, Chih-Wei, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 and Tian, Ya-Chung 2008. Transforming growth factor-β1 decreases epithelial sodium channel functionality in renal collecting duct cells via a Smad4-dependent pathway. Nephrology Dialysis Transplantation 23 (4) , pp. 1126-1134. 10.1093/ndt/gfm786

Nair, S., Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113, Norton, Nadine ORCID: https://orcid.org/0000-0002-3848-4288, Spurlock, Gillian, Williams, Hywel John ORCID: https://orcid.org/0000-0001-7758-0312, Craig, Kathrine Jane, Williams, John David, Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931 and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 2008. Further evidence for the association of MMP9 with nephropathy in type 2 diabetes and application of DNA pooling technology to candidate gene screening. Journal of Nephology 21 (3) , pp. 400-405.

Zhang, M., Lee, C., Luo, D. D., Krupa, A., Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2007. Polarity of response to transforming growth factor-beta1 in proximal tubular epithelial cells is regulated by beta-catenin. Journal of Biological Chemistry 282 (39) , pp. 28639-28647. 10.1074/jbc.m700594200

Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820, Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Martin, John, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 and Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 2007. Involvement of hyaluronan in regulation of fibroblast phenotype. The Journal of Biological Chemistry 282 (35) , pp. 25687-25697. 10.1074/jbc.M700773200

Rashid Selbi, Wisam, de la Motte, C. A., Hascall, V. C., Day, A. J., Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2006. Characterization of hyaluronan cable structure and function in renal proximal tubular epithelial cells. Kidney International 70 (7) , pp. 1287-1295. 10.1038/sj.ki.5001760

Zhang, M., Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2006. ERK, p38, and Smad signaling pathways differentially regulate transforming growth factor-beta1 autoinduction in proximal tubular epithelial cells. American Journal of Pathology 169 (4) , pp. 1282-1293. 10.2353/ajpath.2006.050921

Khera, Tarnjit, Martin, John, Riley, Stephen George, Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2006. Glucose enhances mesangial cell apoptosis. Laboratory Investigation 86 (6) , pp. 566-577. 10.1038/labinvest.3700418

Matsumoto, N., Riley, Stephen George, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342, Al-Assaf, S., Ishimura, E., Wolever, T., Phillips, G. O. and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2006. Butyrate modulates TGF-beta1 generation and function: potential renal benefit for Acacia(sen) SUPERGUM (gum arabic)? Kidney International 69 (2) , pp. 257-65. 10.1038/sj.ki.5000028

Craig, Kathrine Jane, Williams, John David, Riley, Stephen George, Smith, Hilary, Owens, David Raymond, Worthing, Debbie, Cavill, Ivor and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2005. Anemia and diabetes in the absence of nephropathy. Diabetes Care 28 (5) , pp. 1118-1123. 10.2337/diacare.28.5.1118

Zhang, Xiao Liang, Topley, Nicholas, Ito, Takafumi and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2005. Interleukin-6 regulation of transforming growth factor (TGF)-beta receptor compartmentalization and turnover enhances TGF-beta1 signaling. The Journal of Biological Chemistry 280 (13) , pp. 12239-12245. 10.1074/jbc.M413284200

Zhang, Xiao Liang, Rashid Selbi, Wisam Dhafir, Motte, Carol de la, Hascall, Vincent and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2005. Bone morphogenic protein-7 inhibits monocyte-stimulated TGF-beta1 generation in renal proximal tubular epithelial cells. Journal of the American Society of Nephrology 16 (1) , pp. 79-89. 10.1681/ASN.2004050395

Craig, K. L., Riley, Stephen George, Thomas, B., Penney, M., Donovan, Kieron and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2005. The impact of an out-reach clinic on referral of patients with renal impairment. Nephron Clinical Practice 101 (4) , c168-c173. 10.1159/000087392

Zhang, Xiao Liang, Rashid Selbi, Wisam Dhafir, Motte, Carol de la, Hascall, Vincent and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2004. Renal proximal tubular epithelial cell transforming growth factor-beta1 generation and monocyte binding. American Journal of Pathology 165 (3) , pp. 763-773.

Ito, Takafumi, Williams, John David, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2004. Hyaluronan regulates transforming growth factor-beta1 receptor compartmentalization. The Journal of Biological Chemistry 279 (24) , pp. 25326-25332. 10.1074/jbc.M403135200

Ito, T., Williams, J. D., Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342 and Phillips, Aled Owen ORCID: https://orcid.org/0000-0001-9744-7113 2004. Hyaluronan attenuates transforming growth factor-beta1-mediated signaling in renal proximal tubular epithelial cells. American Journal of Pathology 164 (6) , pp. 1979-1988. 10.1016/s0002-9440(10)63758-3

Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342, Brunskill, Nigel, Ito, Takafumi and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2003. Long-term exposure of proximal tubular epithelial cells to glucose induces transforming growth factor-beta 1 synthesis via an autocrine PDGF loop. American Journal of Pathology 163 (6) , pp. 2565-2574.

Tian, Ya-Chung, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342, Attisano, Liliana and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2003. TGF-beta1-mediated alterations of renal proximal tubular epithelial cell phenotype. American Journal of Physiology - Renal Physiology 285 (1) , F130-142. 10.1152/ajprenal.00408.2002

Craig, Kathrine Jane, Donovan, Kieron, Munnery, Margaret, Owens, David Raymond, Williams, John David and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2003. Identification and management of diabetic nephropathy in the diabetes clinic. Diabetes Care 26 (6) , pp. 1806-1811. 10.2337/diacare.26.6.1806

Wong, Teresa Y. H., Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113, Witowski, Janusz and Topley, Nicholas 2003. Glucose-mediated induction of TGF-beta 1 and MCP-1 in mesothelial cells in vitro is osmolality and polyol pathway dependent. Kidney International 63 (4) , pp. 1404-1416. 10.1046/j.1523-1755.2003.00883.x

Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 and Wakefield, Lalage 2002. Independent regulation of transforming growth factor-beta1 transcription and translation by glucose and platelet-derived growth factor. American Journal of Pathology 161 (3) , pp. 1039-1049.